1----- <~time\trenadju.top> Time-Domain Trend Adjustment 2 3Time-Domain Trend Adjustment 4 5Discussion <~time\trenaddi.top> 6 7Check for trends 8 Run sequence plot <xemf: ~plot\runsplot.men> 9 Autocorrelation plot matrix <xemf: ~time\autocpma.men> 10 11Estimate and remove trend 12 Compute first difference <xemf: ~time\differ.men> 13 Lowess fit <xemf: ~time\lowess.men> 14 Linear fit over time <xemf: ~time\linearfi.men> 15 Quadratic fit over time <xemf: ~time\quadfit.men> 16 17