1Entrezgene ::= { 2 track-info { 3 geneid 1 , 4 status live , 5 create-date 6 std { 7 year 2003 , 8 month 8 , 9 day 28 , 10 hour 20 , 11 minute 30 , 12 second 0 } , 13 update-date 14 std { 15 year 2005 , 16 month 4 , 17 day 14 , 18 hour 13 , 19 minute 15 , 20 second 0 } } , 21 type protein-coding , 22 source { 23 genome genomic , 24 origin natural , 25 org { 26 taxname "Homo sapiens" , 27 common "human" , 28 db { 29 { 30 db "taxon" , 31 tag 32 id 9606 } } , 33 syn { 34 "man" } , 35 orgname { 36 name 37 binomial { 38 genus "Homo" , 39 species "sapiens" } , 40 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 41 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 42 Hominidae; Homo" , 43 gcode 1 , 44 mgcode 2 , 45 div "PRI" } } , 46 subtype { 47 { 48 subtype chromosome , 49 name "19" } } } , 50 gene { 51 locus "A1BG" , 52 desc "alpha-1-B glycoprotein" , 53 maploc "19q13.4" , 54 db { 55 { 56 db "MIM" , 57 tag 58 id 138670 } } , 59 syn { 60 "A1B" , 61 "ABG" , 62 "GAB" , 63 "HYST2477" , 64 "DKFZp686F0970" } , 65 locus-tag "HGNC:5" } , 66 prot { 67 name { 68 "alpha 1B-glycoprotein" , 69 "alpha-1B-glycoprotein" } } , 70 summary "The protein encoded by this gene is a plasma glycoprotein of 71 unknown function. The protein shows sequence similarity to the variable 72 regions of some immunoglobulin supergene family member proteins." , 73 location { 74 { 75 display-str "19q13.4" , 76 method 77 map-type cyto } } , 78 gene-source { 79 src "LocusLink" , 80 src-int 1 , 81 src-str2 "1" , 82 gene-display FALSE , 83 locus-display FALSE , 84 extra-terms FALSE } , 85 locus { 86 { 87 type genomic , 88 heading "Reference" , 89 accession "NC_000019" , 90 version 8 , 91 seqs { 92 int { 93 from 63548355 , 94 to 63556668 , 95 strand minus , 96 id 97 gi 42406306 } } , 98 products { 99 { 100 type mRNA , 101 heading "Reference" , 102 accession "NM_130786" , 103 version 2 , 104 genomic-coords { 105 mix { 106 int { 107 from 63548355 , 108 to 63550206 , 109 strand minus , 110 id 111 gi 42406306 } , 112 int { 113 from 63550530 , 114 to 63550817 , 115 strand minus , 116 id 117 gi 42406306 } , 118 int { 119 from 63553547 , 120 to 63553828 , 121 strand minus , 122 id 123 gi 42406306 } , 124 int { 125 from 63554568 , 126 to 63554864 , 127 strand minus , 128 id 129 gi 42406306 } , 130 int { 131 from 63555460 , 132 to 63555732 , 133 strand minus , 134 id 135 gi 42406306 } , 136 int { 137 from 63556105 , 138 to 63556374 , 139 strand minus , 140 id 141 gi 42406306 } , 142 int { 143 from 63556469 , 144 to 63556504 , 145 strand minus , 146 id 147 gi 42406306 } , 148 int { 149 from 63556581 , 150 to 63556668 , 151 strand minus , 152 id 153 gi 42406306 } } } , 154 seqs { 155 whole 156 gi 21071029 } , 157 products { 158 { 159 type peptide , 160 heading "Reference" , 161 accession "NP_570602" , 162 version 2 , 163 genomic-coords { 164 packed-int { 165 { 166 from 63550199 , 167 to 63550206 , 168 strand minus , 169 id 170 gi 42406306 } , 171 { 172 from 63550530 , 173 to 63550817 , 174 strand minus , 175 id 176 gi 42406306 } , 177 { 178 from 63553547 , 179 to 63553828 , 180 strand minus , 181 id 182 gi 42406306 } , 183 { 184 from 63554568 , 185 to 63554864 , 186 strand minus , 187 id 188 gi 42406306 } , 189 { 190 from 63555460 , 191 to 63555732 , 192 strand minus , 193 id 194 gi 42406306 } , 195 { 196 from 63556105 , 197 to 63556374 , 198 strand minus , 199 id 200 gi 42406306 } , 201 { 202 from 63556469 , 203 to 63556504 , 204 strand minus , 205 id 206 gi 42406306 } , 207 { 208 from 63556581 , 209 to 63556614 , 210 strand minus , 211 id 212 gi 42406306 } } } , 213 seqs { 214 whole 215 gi 21071030 } } } } } } , 216 { 217 type genomic , 218 heading "Reference" , 219 accession "NT_011109" , 220 version 15 , 221 seqs { 222 int { 223 from 31124733 , 224 to 31133046 , 225 strand minus , 226 id 227 gi 29800594 } } , 228 products { 229 { 230 type mRNA , 231 heading "Reference" , 232 accession "NM_130786" , 233 version 2 , 234 genomic-coords { 235 mix { 236 int { 237 from 31124733 , 238 to 31126584 , 239 strand minus , 240 id 241 gi 29800594 } , 242 int { 243 from 31126908 , 244 to 31127195 , 245 strand minus , 246 id 247 gi 29800594 } , 248 int { 249 from 31129925 , 250 to 31130206 , 251 strand minus , 252 id 253 gi 29800594 } , 254 int { 255 from 31130946 , 256 to 31131242 , 257 strand minus , 258 id 259 gi 29800594 } , 260 int { 261 from 31131838 , 262 to 31132110 , 263 strand minus , 264 id 265 gi 29800594 } , 266 int { 267 from 31132483 , 268 to 31132752 , 269 strand minus , 270 id 271 gi 29800594 } , 272 int { 273 from 31132847 , 274 to 31132882 , 275 strand minus , 276 id 277 gi 29800594 } , 278 int { 279 from 31132959 , 280 to 31133046 , 281 strand minus , 282 id 283 gi 29800594 } } } , 284 seqs { 285 whole 286 gi 21071029 } , 287 products { 288 { 289 type peptide , 290 heading "Reference" , 291 accession "NP_570602" , 292 version 2 , 293 genomic-coords { 294 packed-int { 295 { 296 from 31126577 , 297 to 31126584 , 298 strand minus , 299 id 300 gi 29800594 } , 301 { 302 from 31126908 , 303 to 31127195 , 304 strand minus , 305 id 306 gi 29800594 } , 307 { 308 from 31129925 , 309 to 31130206 , 310 strand minus , 311 id 312 gi 29800594 } , 313 { 314 from 31130946 , 315 to 31131242 , 316 strand minus , 317 id 318 gi 29800594 } , 319 { 320 from 31131838 , 321 to 31132110 , 322 strand minus , 323 id 324 gi 29800594 } , 325 { 326 from 31132483 , 327 to 31132752 , 328 strand minus , 329 id 330 gi 29800594 } , 331 { 332 from 31132847 , 333 to 31132882 , 334 strand minus , 335 id 336 gi 29800594 } , 337 { 338 from 31132959 , 339 to 31132992 , 340 strand minus , 341 id 342 gi 29800594 } } } , 343 seqs { 344 whole 345 gi 21071030 } } } } } } , 346 { 347 type genomic , 348 heading "Reference" , 349 accession "NT_086907" , 350 version 1 , 351 seqs { 352 int { 353 from 8163589 , 354 to 8172398 , 355 strand minus , 356 id 357 gi 51475048 } } , 358 products { 359 { 360 type mRNA , 361 heading "Reference" , 362 accession "NM_130786" , 363 version 2 , 364 genomic-coords { 365 mix { 366 int { 367 from 8163589 , 368 to 8165440 , 369 strand minus , 370 id 371 gi 51475048 } , 372 int { 373 from 8165763 , 374 to 8166050 , 375 strand minus , 376 id 377 gi 51475048 } , 378 int { 379 from 8169274 , 380 to 8169555 , 381 strand minus , 382 id 383 gi 51475048 } , 384 int { 385 from 8170297 , 386 to 8170593 , 387 strand minus , 388 id 389 gi 51475048 } , 390 int { 391 from 8171190 , 392 to 8171462 , 393 strand minus , 394 id 395 gi 51475048 } , 396 int { 397 from 8171835 , 398 to 8172104 , 399 strand minus , 400 id 401 gi 51475048 } , 402 int { 403 from 8172199 , 404 to 8172234 , 405 strand minus , 406 id 407 gi 51475048 } , 408 int { 409 from 8172311 , 410 to 8172398 , 411 strand minus , 412 id 413 gi 51475048 } } } , 414 seqs { 415 whole 416 gi 21071029 } , 417 products { 418 { 419 type peptide , 420 heading "Reference" , 421 accession "NP_570602" , 422 version 2 , 423 genomic-coords { 424 packed-int { 425 { 426 from 8165433 , 427 to 8165440 , 428 strand minus , 429 id 430 gi 51475048 } , 431 { 432 from 8165763 , 433 to 8166050 , 434 strand minus , 435 id 436 gi 51475048 } , 437 { 438 from 8169274 , 439 to 8169555 , 440 strand minus , 441 id 442 gi 51475048 } , 443 { 444 from 8170297 , 445 to 8170593 , 446 strand minus , 447 id 448 gi 51475048 } , 449 { 450 from 8171190 , 451 to 8171462 , 452 strand minus , 453 id 454 gi 51475048 } , 455 { 456 from 8171835 , 457 to 8172104 , 458 strand minus , 459 id 460 gi 51475048 } , 461 { 462 from 8172199 , 463 to 8172234 , 464 strand minus , 465 id 466 gi 51475048 } , 467 { 468 from 8172311 , 469 to 8172344 , 470 strand minus , 471 id 472 gi 51475048 } } } , 473 seqs { 474 whole 475 gi 21071030 } } } } } } } , 476 properties { 477 { 478 type comment , 479 label "Nomenclature" , 480 version 0 , 481 source { 482 { 483 anchor "HUGO Gene Nomenclature Committee" } } , 484 properties { 485 { 486 type property , 487 label "Official Symbol" , 488 text "A1BG" , 489 version 0 } , 490 { 491 type property , 492 label "Official Full Name" , 493 text "alpha-1-B glycoprotein" , 494 version 0 } } } , 495 { 496 type comment , 497 heading "GeneOntology" , 498 version 0 , 499 source { 500 { 501 pre-text "Provided by" , 502 anchor "GOA" , 503 url "http://www.ebi.ac.uk/GOA/" } } , 504 comment { 505 { 506 type comment , 507 label "Function" , 508 version 0 , 509 comment { 510 { 511 type comment , 512 version 0 , 513 refs { 514 pmid 3458201 } , 515 source { 516 { 517 src { 518 db "GO" , 519 tag 520 id 5554 } , 521 anchor "molecular_function unknown" , 522 post-text "evidence: ND" } } } } } , 523 { 524 type comment , 525 label "Process" , 526 version 0 , 527 comment { 528 { 529 type comment , 530 version 0 , 531 source { 532 { 533 src { 534 db "GO" , 535 tag 536 id 4 } , 537 anchor "biological_process unknown" , 538 post-text "evidence: ND" } } } } } , 539 { 540 type comment , 541 label "Component" , 542 version 0 , 543 comment { 544 { 545 type comment , 546 version 0 , 547 refs { 548 pmid 3458201 } , 549 source { 550 { 551 src { 552 db "GO" , 553 tag 554 id 5576 } , 555 anchor "extracellular region" , 556 post-text "evidence: IDA" } } } } } } } } , 557 homology { 558 { 559 type comment , 560 heading "Mouse, Rat" , 561 version 0 , 562 source { 563 { 564 src { 565 db "HomoloGene" , 566 tag 567 id 11167 } , 568 anchor "Map Viewer" , 569 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=19& 570MAPS=genes-r-org/rat-chr/human%3A19,genes-r-org/mouse-chr/human%3A19,genes-r-o 571rg/human-chr19&query=e%3A1[id]+AND+gene[obj_type]&QSTR=a1bg&cmd=focus&fill=10" } } } } , 572 comments { 573 { 574 type comment , 575 heading "LocusTagLink" , 576 version 0 , 577 source { 578 { 579 src { 580 db "HGNC" , 581 tag 582 id 5 } } } } , 583 { 584 type comment , 585 heading "RefSeq Status" , 586 label "REVIEWED" , 587 version 0 } , 588 { 589 type comment , 590 version 0 , 591 refs { 592 pmid 15461460 , 593 pmid 15221005 , 594 pmid 14702039 , 595 pmid 12477932 , 596 pmid 8889549 , 597 pmid 3610142 , 598 pmid 3458201 , 599 pmid 2591067 } } , 600 { 601 type comment , 602 heading "Markers (Sequence Tagged Sites/STS)" , 603 version 0 , 604 comment { 605 { 606 type comment , 607 version 0 , 608 source { 609 { 610 src { 611 db "UniSTS" , 612 tag 613 id 89991 } , 614 anchor "SHGC-67307" , 615 post-text "(e-PCR)" } } , 616 comment { 617 { 618 type other , 619 label "Alternate name" , 620 text "RH80032" , 621 version 0 } , 622 { 623 type other , 624 label "Alternate name" , 625 text "RH86145" , 626 version 0 } } } , 627 { 628 type comment , 629 version 0 , 630 source { 631 { 632 src { 633 db "UniSTS" , 634 tag 635 id 152074 } , 636 anchor "D11S2921" , 637 post-text "(e-PCR)" } } , 638 comment { 639 { 640 type other , 641 label "Alternate name" , 642 text "GDB:461809" , 643 version 0 } } } , 644 { 645 type comment , 646 version 0 , 647 source { 648 { 649 src { 650 db "UniSTS" , 651 tag 652 id 155756 } , 653 anchor "D10S16" , 654 post-text "(e-PCR)" } } , 655 comment { 656 { 657 type other , 658 label "Alternate name" , 659 text "D10S23" , 660 version 0 } , 661 { 662 type other , 663 label "Alternate name" , 664 text "GDB:193809" , 665 version 0 } } } } } , 666 { 667 type comment , 668 heading "NCBI Reference Sequences (RefSeq)" , 669 version 0 , 670 products { 671 { 672 type mRNA , 673 heading "mRNA Sequence" , 674 accession "NM_130786" , 675 version 2 , 676 source { 677 { 678 src { 679 db "Nucleotide" , 680 tag 681 id 21071029 } , 682 anchor "NM_130786" } } , 683 seqs { 684 whole 685 gi 21071029 } , 686 products { 687 { 688 type peptide , 689 heading "Product" , 690 accession "NP_570602" , 691 version 2 , 692 source { 693 { 694 src { 695 db "Protein" , 696 tag 697 id 21071030 } , 698 anchor "NP_570602" , 699 post-text "alpha 1B-glycoprotein" } } , 700 seqs { 701 whole 702 gi 21071030 } , 703 comment { 704 { 705 type other , 706 heading "Consensus CDS (CCDS)" , 707 version 0 , 708 source { 709 { 710 src { 711 db "CCDS" , 712 tag 713 str "CCDS12976.1" } , 714 anchor "CCDS12976.1" } } } , 715 { 716 type other , 717 heading "Conserved Domains" , 718 version 0 , 719 source { 720 { 721 src { 722 db "PROT_CDD" , 723 tag 724 id 21071030 } , 725 pre-text "(1)" , 726 anchor "summary" } } , 727 comment { 728 { 729 type other , 730 version 0 , 731 source { 732 { 733 src { 734 db "CDD" , 735 tag 736 id 365 } , 737 anchor "smart00408: IGc2; Immunoglobulin C-2 Type" } } , 738 comment { 739 { 740 type other , 741 text "Location: 223 - 282 Blast Score: 103" , 742 version 0 } } } } } } } } , 743 comment { 744 { 745 type other , 746 heading "Source Sequence" , 747 version 0 , 748 source { 749 { 750 src { 751 db "Nucleotide" , 752 tag 753 str "AF414429,AK055885,AK056201" } , 754 anchor "AF414429,AK055885,AK056201" } } , 755 comment { 756 { 757 type other , 758 version 0 } } } } } } } , 759 { 760 type comment , 761 heading "Related Sequences" , 762 version 0 , 763 products { 764 { 765 type genomic , 766 heading "Genomic" , 767 accession "AC010642" , 768 version 5 , 769 source { 770 { 771 src { 772 db "Nucleotide" , 773 tag 774 id 9929687 } , 775 anchor "AC010642" } } , 776 seqs { 777 int { 778 from 41119 , 779 to 43581 , 780 strand plus , 781 id 782 gi 9929687 } } , 783 products { 784 { 785 type peptide , 786 text "None" , 787 version 0 } } } , 788 { 789 type mRNA , 790 heading "mRNA" , 791 accession "AB073611" , 792 version 1 , 793 source { 794 { 795 src { 796 db "Nucleotide" , 797 tag 798 id 51555784 } , 799 anchor "AB073611" } } , 800 seqs { 801 whole 802 gi 51555784 } , 803 products { 804 { 805 type peptide , 806 accession "BAD38648" , 807 version 1 , 808 source { 809 { 810 src { 811 db "Protein" , 812 tag 813 id 51555785 } , 814 anchor "BAD38648" } } , 815 seqs { 816 whole 817 gi 51555785 } } } } , 818 { 819 type mRNA , 820 heading "mRNA" , 821 accession "AF414429" , 822 version 1 , 823 source { 824 { 825 src { 826 db "Nucleotide" , 827 tag 828 id 15778555 } , 829 anchor "AF414429" } } , 830 seqs { 831 whole 832 gi 15778555 } , 833 products { 834 { 835 type peptide , 836 accession "AAL07469" , 837 version 1 , 838 source { 839 { 840 src { 841 db "Protein" , 842 tag 843 id 15778556 } , 844 anchor "AAL07469" } } , 845 seqs { 846 whole 847 gi 15778556 } } } } , 848 { 849 type mRNA , 850 heading "mRNA" , 851 accession "AK055885" , 852 version 1 , 853 source { 854 { 855 src { 856 db "Nucleotide" , 857 tag 858 id 16550723 } , 859 anchor "AK055885" } } , 860 seqs { 861 whole 862 gi 16550723 } , 863 products { 864 { 865 type peptide , 866 text "None" , 867 version 0 } } } , 868 { 869 type mRNA , 870 heading "mRNA" , 871 accession "AK056201" , 872 version 1 , 873 source { 874 { 875 src { 876 db "Nucleotide" , 877 tag 878 id 16551539 } , 879 anchor "AK056201" } } , 880 seqs { 881 whole 882 gi 16551539 } , 883 products { 884 { 885 type peptide , 886 text "None" , 887 version 0 } } } , 888 { 889 type mRNA , 890 heading "mRNA" , 891 accession "BC035719" , 892 version 1 , 893 source { 894 { 895 src { 896 db "Nucleotide" , 897 tag 898 id 23273475 } , 899 anchor "BC035719" } } , 900 seqs { 901 whole 902 gi 23273475 } , 903 products { 904 { 905 type peptide , 906 accession "AAH35719" , 907 version 1 , 908 source { 909 { 910 src { 911 db "Protein" , 912 tag 913 id 23273476 } , 914 anchor "AAH35719" } } , 915 seqs { 916 whole 917 gi 23273476 } } } } , 918 { 919 type mRNA , 920 heading "mRNA" , 921 accession "BX537419" , 922 version 1 , 923 source { 924 { 925 src { 926 db "Nucleotide" , 927 tag 928 id 31873339 } , 929 anchor "BX537419" } } , 930 seqs { 931 whole 932 gi 31873339 } , 933 products { 934 { 935 type peptide , 936 accession "CAD97661" , 937 version 1 , 938 source { 939 { 940 src { 941 db "Protein" , 942 tag 943 id 31873340 } , 944 anchor "CAD97661" } } , 945 seqs { 946 whole 947 gi 31873340 } } } } , 948 { 949 type other , 950 text "None" , 951 version 0 , 952 products { 953 { 954 type peptide , 955 accession "P04217" , 956 version 0 , 957 source { 958 { 959 src { 960 db "Protein" , 961 tag 962 id 46577680 } , 963 anchor "P04217" } } , 964 seqs { 965 whole 966 gi 46577680 } } } } } } , 967 { 968 type comment , 969 heading "Additional Links" , 970 version 0 , 971 comment { 972 { 973 type comment , 974 version 0 , 975 source { 976 { 977 src { 978 db "Evidence Viewer" , 979 tag 980 str "1" } , 981 anchor "Evidence Viewer" , 982 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 983g=NT_011109.15&gene=A1BG&lid=1&from=31124734&to=31133047" } } } , 984 { 985 type comment , 986 version 0 , 987 source { 988 { 989 src { 990 db "ModelMaker" , 991 tag 992 str "1" } , 993 anchor "ModelMaker" , 994 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 99506&contig=NT_011109.15&gene=A1BG&lid=1" } } } , 996 { 997 type comment , 998 text "UniGene" , 999 version 0 , 1000 xtra-properties { 1001 { 1002 tag "UNIGENE" , 1003 value "Hs.529161" } } , 1004 source { 1005 { 1006 src { 1007 db "UniGene" , 1008 tag 1009 str "Hs.529161" } , 1010 anchor "Hs.529161" , 1011 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=52 10129161" } } } , 1013 { 1014 type comment , 1015 text "MIM" , 1016 version 0 , 1017 source { 1018 { 1019 src { 1020 db "MIM" , 1021 tag 1022 str "138670" } , 1023 anchor "138670" } } } , 1024 { 1025 type comment , 1026 version 0 , 1027 source { 1028 { 1029 src { 1030 db "HomoloGene" , 1031 tag 1032 str "1" } , 1033 anchor "HomoloGene" , 1034 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 10351[loc]&TAXID=9606" } } } , 1036 { 1037 type comment , 1038 version 0 , 1039 source { 1040 { 1041 src { 1042 db "AceView" , 1043 tag 1044 id 1 } , 1045 anchor "AceView" , 1046 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 1047ocusid&org=9606&l=1" } } } , 1048 { 1049 type comment , 1050 version 0 , 1051 source { 1052 { 1053 src { 1054 db "GDB" , 1055 tag 1056 str "GDB:119638" } } } } , 1057 { 1058 type comment , 1059 version 0 , 1060 source { 1061 { 1062 src { 1063 db "Ensembl" , 1064 tag 1065 str "" } , 1066 url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=AK055 1067885" } } } , 1068 { 1069 type comment , 1070 version 0 , 1071 source { 1072 { 1073 src { 1074 db "UCSC" , 1075 tag 1076 str "" } , 1077 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position= 1078AK055885" } } } , 1079 { 1080 type comment , 1081 version 0 , 1082 source { 1083 { 1084 src { 1085 db "MGC" , 1086 tag 1087 str "BC035719" } , 1088 anchor "MGC" , 1089 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC035719" } } } } } , 1090 { 1091 type generif , 1092 text "A1BG-cysteine-rich secretory protein 3 complex displays a similar 1093 function in protecting the circulation from a potentially harmful effect of 1094 free CRISP-3" , 1095 version 0 , 1096 refs { 1097 pmid 15461460 } , 1098 create-date 1099 str "Nov 6 2004 10:01AM" , 1100 update-date 1101 str "Nov 6 2004 3:27PM" } } , 1102 unique-keys { 1103 { 1104 db "LocusID" , 1105 tag 1106 id 1 } , 1107 { 1108 db "MIM" , 1109 tag 1110 id 138670 } } , 1111 xtra-index-terms { 1112 "LOC1" } } 1113Entrezgene ::= { 1114 track-info { 1115 geneid 2 , 1116 status live , 1117 create-date 1118 std { 1119 year 2003 , 1120 month 8 , 1121 day 28 , 1122 hour 20 , 1123 minute 30 , 1124 second 0 } , 1125 update-date 1126 std { 1127 year 2005 , 1128 month 4 , 1129 day 14 , 1130 hour 13 , 1131 minute 15 , 1132 second 0 } } , 1133 type protein-coding , 1134 source { 1135 genome genomic , 1136 origin natural , 1137 org { 1138 taxname "Homo sapiens" , 1139 common "human" , 1140 db { 1141 { 1142 db "taxon" , 1143 tag 1144 id 9606 } } , 1145 syn { 1146 "man" } , 1147 orgname { 1148 name 1149 binomial { 1150 genus "Homo" , 1151 species "sapiens" } , 1152 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 1153 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 1154 Hominidae; Homo" , 1155 gcode 1 , 1156 mgcode 2 , 1157 div "PRI" } } , 1158 subtype { 1159 { 1160 subtype chromosome , 1161 name "12" } } } , 1162 gene { 1163 locus "A2M" , 1164 desc "alpha-2-macroglobulin" , 1165 maploc "12p13.3-p12.3" , 1166 db { 1167 { 1168 db "MIM" , 1169 tag 1170 id 103950 } } , 1171 syn { 1172 "FWP007" , 1173 "S863-7" , 1174 "DKFZp779B086" } , 1175 locus-tag "HGNC:7" } , 1176 prot { 1177 name { 1178 "alpha-2-macroglobulin" } } , 1179 summary "Alpha-2-macroglobulin is a protease inhibitor and cytokine 1180 transporter. It inhibits many proteases, including trypsin, thrombin and 1181 collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability 1182 to mediate the clearance and degradation of A-beta, the major component of 1183 beta-amyloid deposits." , 1184 location { 1185 { 1186 display-str "12p13.3-p12.3" , 1187 method 1188 map-type cyto } } , 1189 gene-source { 1190 src "LocusLink" , 1191 src-int 2 , 1192 src-str2 "2" , 1193 gene-display FALSE , 1194 locus-display FALSE , 1195 extra-terms FALSE } , 1196 locus { 1197 { 1198 type genomic , 1199 heading "Reference" , 1200 accession "NC_000012" , 1201 version 9 , 1202 seqs { 1203 int { 1204 from 9111576 , 1205 to 9159755 , 1206 strand minus , 1207 id 1208 gi 51511728 } } , 1209 products { 1210 { 1211 type mRNA , 1212 heading "Reference" , 1213 accession "NM_000014" , 1214 version 3 , 1215 genomic-coords { 1216 mix { 1217 int { 1218 from 9111576 , 1219 to 9111701 , 1220 strand minus , 1221 id 1222 gi 51511728 } , 1223 int { 1224 from 9112045 , 1225 to 9112086 , 1226 strand minus , 1227 id 1228 gi 51511728 } , 1229 int { 1230 from 9112602 , 1231 to 9112704 , 1232 strand minus , 1233 id 1234 gi 51511728 } , 1235 int { 1236 from 9113607 , 1237 to 9113675 , 1238 strand minus , 1239 id 1240 gi 51511728 } , 1241 int { 1242 from 9114350 , 1243 to 9114440 , 1244 strand minus , 1245 id 1246 gi 51511728 } , 1247 int { 1248 from 9116221 , 1249 to 9116348 , 1250 strand minus , 1251 id 1252 gi 51511728 } , 1253 int { 1254 from 9116515 , 1255 to 9116733 , 1256 strand minus , 1257 id 1258 gi 51511728 } , 1259 int { 1260 from 9118422 , 1261 to 9118645 , 1262 strand minus , 1263 id 1264 gi 51511728 } , 1265 int { 1266 from 9120618 , 1267 to 9120798 , 1268 strand minus , 1269 id 1270 gi 51511728 } , 1271 int { 1272 from 9121208 , 1273 to 9121282 , 1274 strand minus , 1275 id 1276 gi 51511728 } , 1277 int { 1278 from 9121563 , 1279 to 9121719 , 1280 strand minus , 1281 id 1282 gi 51511728 } , 1283 int { 1284 from 9123106 , 1285 to 9123193 , 1286 strand minus , 1287 id 1288 gi 51511728 } , 1289 int { 1290 from 9123501 , 1291 to 9123677 , 1292 strand minus , 1293 id 1294 gi 51511728 } , 1295 int { 1296 from 9123956 , 1297 to 9124039 , 1298 strand minus , 1299 id 1300 gi 51511728 } , 1301 int { 1302 from 9133062 , 1303 to 9133113 , 1304 strand minus , 1305 id 1306 gi 51511728 } , 1307 int { 1308 from 9133764 , 1309 to 9133885 , 1310 strand minus , 1311 id 1312 gi 51511728 } , 1313 int { 1314 from 9134218 , 1315 to 9134344 , 1316 strand minus , 1317 id 1318 gi 51511728 } , 1319 int { 1320 from 9135063 , 1321 to 9135291 , 1322 strand minus , 1323 id 1324 gi 51511728 } , 1325 int { 1326 from 9137327 , 1327 to 9137441 , 1328 strand minus , 1329 id 1330 gi 51511728 } , 1331 int { 1332 from 9138835 , 1333 to 9138946 , 1334 strand minus , 1335 id 1336 gi 51511728 } , 1337 int { 1338 from 9139401 , 1339 to 9139562 , 1340 strand minus , 1341 id 1342 gi 51511728 } , 1343 int { 1344 from 9142469 , 1345 to 9142618 , 1346 strand minus , 1347 id 1348 gi 51511728 } , 1349 int { 1350 from 9143243 , 1351 to 9143385 , 1352 strand minus , 1353 id 1354 gi 51511728 } , 1355 int { 1356 from 9145006 , 1357 to 9145069 , 1358 strand minus , 1359 id 1360 gi 51511728 } , 1361 int { 1362 from 9145309 , 1363 to 9145536 , 1364 strand minus , 1365 id 1366 gi 51511728 } , 1367 int { 1368 from 9148101 , 1369 to 9148262 , 1370 strand minus , 1371 id 1372 gi 51511728 } , 1373 int { 1374 from 9150098 , 1375 to 9150207 , 1376 strand minus , 1377 id 1378 gi 51511728 } , 1379 int { 1380 from 9150353 , 1381 to 9150467 , 1382 strand minus , 1383 id 1384 gi 51511728 } , 1385 int { 1386 from 9151386 , 1387 to 9151506 , 1388 strand minus , 1389 id 1390 gi 51511728 } , 1391 int { 1392 from 9153183 , 1393 to 9153267 , 1394 strand minus , 1395 id 1396 gi 51511728 } , 1397 int { 1398 from 9153729 , 1399 to 9153897 , 1400 strand minus , 1401 id 1402 gi 51511728 } , 1403 int { 1404 from 9154176 , 1405 to 9154196 , 1406 strand minus , 1407 id 1408 gi 51511728 } , 1409 int { 1410 from 9156021 , 1411 to 9156073 , 1412 strand minus , 1413 id 1414 gi 51511728 } , 1415 int { 1416 from 9156239 , 1417 to 9156398 , 1418 strand minus , 1419 id 1420 gi 51511728 } , 1421 int { 1422 from 9157222 , 1423 to 9157405 , 1424 strand minus , 1425 id 1426 gi 51511728 } , 1427 int { 1428 from 9159626 , 1429 to 9159755 , 1430 strand minus , 1431 id 1432 gi 51511728 } } } , 1433 seqs { 1434 whole 1435 gi 6226959 } , 1436 products { 1437 { 1438 type peptide , 1439 heading "Reference" , 1440 label "precursor" , 1441 accession "NP_000005" , 1442 version 1 , 1443 genomic-coords { 1444 packed-int { 1445 { 1446 from 9111685 , 1447 to 9111701 , 1448 strand minus , 1449 id 1450 gi 51511728 } , 1451 { 1452 from 9112045 , 1453 to 9112086 , 1454 strand minus , 1455 id 1456 gi 51511728 } , 1457 { 1458 from 9112602 , 1459 to 9112704 , 1460 strand minus , 1461 id 1462 gi 51511728 } , 1463 { 1464 from 9113607 , 1465 to 9113675 , 1466 strand minus , 1467 id 1468 gi 51511728 } , 1469 { 1470 from 9114350 , 1471 to 9114440 , 1472 strand minus , 1473 id 1474 gi 51511728 } , 1475 { 1476 from 9116221 , 1477 to 9116348 , 1478 strand minus , 1479 id 1480 gi 51511728 } , 1481 { 1482 from 9116515 , 1483 to 9116733 , 1484 strand minus , 1485 id 1486 gi 51511728 } , 1487 { 1488 from 9118422 , 1489 to 9118645 , 1490 strand minus , 1491 id 1492 gi 51511728 } , 1493 { 1494 from 9120618 , 1495 to 9120798 , 1496 strand minus , 1497 id 1498 gi 51511728 } , 1499 { 1500 from 9121208 , 1501 to 9121282 , 1502 strand minus , 1503 id 1504 gi 51511728 } , 1505 { 1506 from 9121563 , 1507 to 9121719 , 1508 strand minus , 1509 id 1510 gi 51511728 } , 1511 { 1512 from 9123106 , 1513 to 9123193 , 1514 strand minus , 1515 id 1516 gi 51511728 } , 1517 { 1518 from 9123501 , 1519 to 9123677 , 1520 strand minus , 1521 id 1522 gi 51511728 } , 1523 { 1524 from 9123956 , 1525 to 9124039 , 1526 strand minus , 1527 id 1528 gi 51511728 } , 1529 { 1530 from 9133062 , 1531 to 9133113 , 1532 strand minus , 1533 id 1534 gi 51511728 } , 1535 { 1536 from 9133764 , 1537 to 9133885 , 1538 strand minus , 1539 id 1540 gi 51511728 } , 1541 { 1542 from 9134218 , 1543 to 9134344 , 1544 strand minus , 1545 id 1546 gi 51511728 } , 1547 { 1548 from 9135063 , 1549 to 9135291 , 1550 strand minus , 1551 id 1552 gi 51511728 } , 1553 { 1554 from 9137327 , 1555 to 9137441 , 1556 strand minus , 1557 id 1558 gi 51511728 } , 1559 { 1560 from 9138835 , 1561 to 9138946 , 1562 strand minus , 1563 id 1564 gi 51511728 } , 1565 { 1566 from 9139401 , 1567 to 9139562 , 1568 strand minus , 1569 id 1570 gi 51511728 } , 1571 { 1572 from 9142469 , 1573 to 9142618 , 1574 strand minus , 1575 id 1576 gi 51511728 } , 1577 { 1578 from 9143243 , 1579 to 9143385 , 1580 strand minus , 1581 id 1582 gi 51511728 } , 1583 { 1584 from 9145006 , 1585 to 9145069 , 1586 strand minus , 1587 id 1588 gi 51511728 } , 1589 { 1590 from 9145309 , 1591 to 9145536 , 1592 strand minus , 1593 id 1594 gi 51511728 } , 1595 { 1596 from 9148101 , 1597 to 9148262 , 1598 strand minus , 1599 id 1600 gi 51511728 } , 1601 { 1602 from 9150098 , 1603 to 9150207 , 1604 strand minus , 1605 id 1606 gi 51511728 } , 1607 { 1608 from 9150353 , 1609 to 9150467 , 1610 strand minus , 1611 id 1612 gi 51511728 } , 1613 { 1614 from 9151386 , 1615 to 9151506 , 1616 strand minus , 1617 id 1618 gi 51511728 } , 1619 { 1620 from 9153183 , 1621 to 9153267 , 1622 strand minus , 1623 id 1624 gi 51511728 } , 1625 { 1626 from 9153729 , 1627 to 9153897 , 1628 strand minus , 1629 id 1630 gi 51511728 } , 1631 { 1632 from 9154176 , 1633 to 9154196 , 1634 strand minus , 1635 id 1636 gi 51511728 } , 1637 { 1638 from 9156021 , 1639 to 9156073 , 1640 strand minus , 1641 id 1642 gi 51511728 } , 1643 { 1644 from 9156239 , 1645 to 9156398 , 1646 strand minus , 1647 id 1648 gi 51511728 } , 1649 { 1650 from 9157222 , 1651 to 9157405 , 1652 strand minus , 1653 id 1654 gi 51511728 } , 1655 { 1656 from 9159626 , 1657 to 9159711 , 1658 strand minus , 1659 id 1660 gi 51511728 } } } , 1661 seqs { 1662 whole 1663 gi 4557225 } } } } } } , 1664 { 1665 type genomic , 1666 heading "Reference" , 1667 accession "NT_009714" , 1668 version 16 , 1669 seqs { 1670 int { 1671 from 1979283 , 1672 to 2027462 , 1673 strand minus , 1674 id 1675 gi 37543832 } } , 1676 products { 1677 { 1678 type mRNA , 1679 heading "Reference" , 1680 accession "NM_000014" , 1681 version 3 , 1682 genomic-coords { 1683 mix { 1684 int { 1685 from 1979283 , 1686 to 1979408 , 1687 strand minus , 1688 id 1689 gi 37543832 } , 1690 int { 1691 from 1979752 , 1692 to 1979793 , 1693 strand minus , 1694 id 1695 gi 37543832 } , 1696 int { 1697 from 1980309 , 1698 to 1980411 , 1699 strand minus , 1700 id 1701 gi 37543832 } , 1702 int { 1703 from 1981314 , 1704 to 1981382 , 1705 strand minus , 1706 id 1707 gi 37543832 } , 1708 int { 1709 from 1982057 , 1710 to 1982147 , 1711 strand minus , 1712 id 1713 gi 37543832 } , 1714 int { 1715 from 1983928 , 1716 to 1984055 , 1717 strand minus , 1718 id 1719 gi 37543832 } , 1720 int { 1721 from 1984222 , 1722 to 1984440 , 1723 strand minus , 1724 id 1725 gi 37543832 } , 1726 int { 1727 from 1986129 , 1728 to 1986352 , 1729 strand minus , 1730 id 1731 gi 37543832 } , 1732 int { 1733 from 1988325 , 1734 to 1988505 , 1735 strand minus , 1736 id 1737 gi 37543832 } , 1738 int { 1739 from 1988915 , 1740 to 1988989 , 1741 strand minus , 1742 id 1743 gi 37543832 } , 1744 int { 1745 from 1989270 , 1746 to 1989426 , 1747 strand minus , 1748 id 1749 gi 37543832 } , 1750 int { 1751 from 1990813 , 1752 to 1990900 , 1753 strand minus , 1754 id 1755 gi 37543832 } , 1756 int { 1757 from 1991208 , 1758 to 1991384 , 1759 strand minus , 1760 id 1761 gi 37543832 } , 1762 int { 1763 from 1991663 , 1764 to 1991746 , 1765 strand minus , 1766 id 1767 gi 37543832 } , 1768 int { 1769 from 2000769 , 1770 to 2000820 , 1771 strand minus , 1772 id 1773 gi 37543832 } , 1774 int { 1775 from 2001471 , 1776 to 2001592 , 1777 strand minus , 1778 id 1779 gi 37543832 } , 1780 int { 1781 from 2001925 , 1782 to 2002051 , 1783 strand minus , 1784 id 1785 gi 37543832 } , 1786 int { 1787 from 2002770 , 1788 to 2002998 , 1789 strand minus , 1790 id 1791 gi 37543832 } , 1792 int { 1793 from 2005034 , 1794 to 2005148 , 1795 strand minus , 1796 id 1797 gi 37543832 } , 1798 int { 1799 from 2006542 , 1800 to 2006653 , 1801 strand minus , 1802 id 1803 gi 37543832 } , 1804 int { 1805 from 2007108 , 1806 to 2007269 , 1807 strand minus , 1808 id 1809 gi 37543832 } , 1810 int { 1811 from 2010176 , 1812 to 2010325 , 1813 strand minus , 1814 id 1815 gi 37543832 } , 1816 int { 1817 from 2010950 , 1818 to 2011092 , 1819 strand minus , 1820 id 1821 gi 37543832 } , 1822 int { 1823 from 2012713 , 1824 to 2012776 , 1825 strand minus , 1826 id 1827 gi 37543832 } , 1828 int { 1829 from 2013016 , 1830 to 2013243 , 1831 strand minus , 1832 id 1833 gi 37543832 } , 1834 int { 1835 from 2015808 , 1836 to 2015969 , 1837 strand minus , 1838 id 1839 gi 37543832 } , 1840 int { 1841 from 2017805 , 1842 to 2017914 , 1843 strand minus , 1844 id 1845 gi 37543832 } , 1846 int { 1847 from 2018060 , 1848 to 2018174 , 1849 strand minus , 1850 id 1851 gi 37543832 } , 1852 int { 1853 from 2019093 , 1854 to 2019213 , 1855 strand minus , 1856 id 1857 gi 37543832 } , 1858 int { 1859 from 2020890 , 1860 to 2020974 , 1861 strand minus , 1862 id 1863 gi 37543832 } , 1864 int { 1865 from 2021436 , 1866 to 2021604 , 1867 strand minus , 1868 id 1869 gi 37543832 } , 1870 int { 1871 from 2021883 , 1872 to 2021903 , 1873 strand minus , 1874 id 1875 gi 37543832 } , 1876 int { 1877 from 2023728 , 1878 to 2023780 , 1879 strand minus , 1880 id 1881 gi 37543832 } , 1882 int { 1883 from 2023946 , 1884 to 2024105 , 1885 strand minus , 1886 id 1887 gi 37543832 } , 1888 int { 1889 from 2024929 , 1890 to 2025112 , 1891 strand minus , 1892 id 1893 gi 37543832 } , 1894 int { 1895 from 2027333 , 1896 to 2027462 , 1897 strand minus , 1898 id 1899 gi 37543832 } } } , 1900 seqs { 1901 whole 1902 gi 6226959 } , 1903 products { 1904 { 1905 type peptide , 1906 heading "Reference" , 1907 label "precursor" , 1908 accession "NP_000005" , 1909 version 1 , 1910 genomic-coords { 1911 packed-int { 1912 { 1913 from 1979392 , 1914 to 1979408 , 1915 strand minus , 1916 id 1917 gi 37543832 } , 1918 { 1919 from 1979752 , 1920 to 1979793 , 1921 strand minus , 1922 id 1923 gi 37543832 } , 1924 { 1925 from 1980309 , 1926 to 1980411 , 1927 strand minus , 1928 id 1929 gi 37543832 } , 1930 { 1931 from 1981314 , 1932 to 1981382 , 1933 strand minus , 1934 id 1935 gi 37543832 } , 1936 { 1937 from 1982057 , 1938 to 1982147 , 1939 strand minus , 1940 id 1941 gi 37543832 } , 1942 { 1943 from 1983928 , 1944 to 1984055 , 1945 strand minus , 1946 id 1947 gi 37543832 } , 1948 { 1949 from 1984222 , 1950 to 1984440 , 1951 strand minus , 1952 id 1953 gi 37543832 } , 1954 { 1955 from 1986129 , 1956 to 1986352 , 1957 strand minus , 1958 id 1959 gi 37543832 } , 1960 { 1961 from 1988325 , 1962 to 1988505 , 1963 strand minus , 1964 id 1965 gi 37543832 } , 1966 { 1967 from 1988915 , 1968 to 1988989 , 1969 strand minus , 1970 id 1971 gi 37543832 } , 1972 { 1973 from 1989270 , 1974 to 1989426 , 1975 strand minus , 1976 id 1977 gi 37543832 } , 1978 { 1979 from 1990813 , 1980 to 1990900 , 1981 strand minus , 1982 id 1983 gi 37543832 } , 1984 { 1985 from 1991208 , 1986 to 1991384 , 1987 strand minus , 1988 id 1989 gi 37543832 } , 1990 { 1991 from 1991663 , 1992 to 1991746 , 1993 strand minus , 1994 id 1995 gi 37543832 } , 1996 { 1997 from 2000769 , 1998 to 2000820 , 1999 strand minus , 2000 id 2001 gi 37543832 } , 2002 { 2003 from 2001471 , 2004 to 2001592 , 2005 strand minus , 2006 id 2007 gi 37543832 } , 2008 { 2009 from 2001925 , 2010 to 2002051 , 2011 strand minus , 2012 id 2013 gi 37543832 } , 2014 { 2015 from 2002770 , 2016 to 2002998 , 2017 strand minus , 2018 id 2019 gi 37543832 } , 2020 { 2021 from 2005034 , 2022 to 2005148 , 2023 strand minus , 2024 id 2025 gi 37543832 } , 2026 { 2027 from 2006542 , 2028 to 2006653 , 2029 strand minus , 2030 id 2031 gi 37543832 } , 2032 { 2033 from 2007108 , 2034 to 2007269 , 2035 strand minus , 2036 id 2037 gi 37543832 } , 2038 { 2039 from 2010176 , 2040 to 2010325 , 2041 strand minus , 2042 id 2043 gi 37543832 } , 2044 { 2045 from 2010950 , 2046 to 2011092 , 2047 strand minus , 2048 id 2049 gi 37543832 } , 2050 { 2051 from 2012713 , 2052 to 2012776 , 2053 strand minus , 2054 id 2055 gi 37543832 } , 2056 { 2057 from 2013016 , 2058 to 2013243 , 2059 strand minus , 2060 id 2061 gi 37543832 } , 2062 { 2063 from 2015808 , 2064 to 2015969 , 2065 strand minus , 2066 id 2067 gi 37543832 } , 2068 { 2069 from 2017805 , 2070 to 2017914 , 2071 strand minus , 2072 id 2073 gi 37543832 } , 2074 { 2075 from 2018060 , 2076 to 2018174 , 2077 strand minus , 2078 id 2079 gi 37543832 } , 2080 { 2081 from 2019093 , 2082 to 2019213 , 2083 strand minus , 2084 id 2085 gi 37543832 } , 2086 { 2087 from 2020890 , 2088 to 2020974 , 2089 strand minus , 2090 id 2091 gi 37543832 } , 2092 { 2093 from 2021436 , 2094 to 2021604 , 2095 strand minus , 2096 id 2097 gi 37543832 } , 2098 { 2099 from 2021883 , 2100 to 2021903 , 2101 strand minus , 2102 id 2103 gi 37543832 } , 2104 { 2105 from 2023728 , 2106 to 2023780 , 2107 strand minus , 2108 id 2109 gi 37543832 } , 2110 { 2111 from 2023946 , 2112 to 2024105 , 2113 strand minus , 2114 id 2115 gi 37543832 } , 2116 { 2117 from 2024929 , 2118 to 2025112 , 2119 strand minus , 2120 id 2121 gi 37543832 } , 2122 { 2123 from 2027333 , 2124 to 2027418 , 2125 strand minus , 2126 id 2127 gi 37543832 } } } , 2128 seqs { 2129 whole 2130 gi 4557225 } } } } } } , 2131 { 2132 type genomic , 2133 heading "Reference" , 2134 accession "NT_086792" , 2135 version 1 , 2136 seqs { 2137 int { 2138 from 4173171 , 2139 to 4221277 , 2140 strand minus , 2141 id 2142 gi 51471135 } } , 2143 products { 2144 { 2145 type mRNA , 2146 heading "Reference" , 2147 accession "NM_000014" , 2148 version 3 , 2149 genomic-coords { 2150 mix { 2151 int { 2152 from 4173171 , 2153 to 4173296 , 2154 strand minus , 2155 id 2156 gi 51471135 } , 2157 int { 2158 from 4173640 , 2159 to 4173681 , 2160 strand minus , 2161 id 2162 gi 51471135 } , 2163 int { 2164 from 4174197 , 2165 to 4174299 , 2166 strand minus , 2167 id 2168 gi 51471135 } , 2169 int { 2170 from 4175201 , 2171 to 4175269 , 2172 strand minus , 2173 id 2174 gi 51471135 } , 2175 int { 2176 from 4175944 , 2177 to 4176034 , 2178 strand minus , 2179 id 2180 gi 51471135 } , 2181 int { 2182 from 4177816 , 2183 to 4177943 , 2184 strand minus , 2185 id 2186 gi 51471135 } , 2187 int { 2188 from 4178110 , 2189 to 4178328 , 2190 strand minus , 2191 id 2192 gi 51471135 } , 2193 int { 2194 from 4180017 , 2195 to 4180240 , 2196 strand minus , 2197 id 2198 gi 51471135 } , 2199 int { 2200 from 4182213 , 2201 to 4182393 , 2202 strand minus , 2203 id 2204 gi 51471135 } , 2205 int { 2206 from 4182803 , 2207 to 4182877 , 2208 strand minus , 2209 id 2210 gi 51471135 } , 2211 int { 2212 from 4183158 , 2213 to 4183314 , 2214 strand minus , 2215 id 2216 gi 51471135 } , 2217 int { 2218 from 4184702 , 2219 to 4184789 , 2220 strand minus , 2221 id 2222 gi 51471135 } , 2223 int { 2224 from 4185097 , 2225 to 4185273 , 2226 strand minus , 2227 id 2228 gi 51471135 } , 2229 int { 2230 from 4185552 , 2231 to 4185635 , 2232 strand minus , 2233 id 2234 gi 51471135 } , 2235 int { 2236 from 4194661 , 2237 to 4194712 , 2238 strand minus , 2239 id 2240 gi 51471135 } , 2241 int { 2242 from 4195363 , 2243 to 4195484 , 2244 strand minus , 2245 id 2246 gi 51471135 } , 2247 int { 2248 from 4195817 , 2249 to 4195943 , 2250 strand minus , 2251 id 2252 gi 51471135 } , 2253 int { 2254 from 4196662 , 2255 to 4196890 , 2256 strand minus , 2257 id 2258 gi 51471135 } , 2259 int { 2260 from 4198926 , 2261 to 4199040 , 2262 strand minus , 2263 id 2264 gi 51471135 } , 2265 int { 2266 from 4200364 , 2267 to 4200475 , 2268 strand minus , 2269 id 2270 gi 51471135 } , 2271 int { 2272 from 4200930 , 2273 to 4201091 , 2274 strand minus , 2275 id 2276 gi 51471135 } , 2277 int { 2278 from 4203997 , 2279 to 4204146 , 2280 strand minus , 2281 id 2282 gi 51471135 } , 2283 int { 2284 from 4204771 , 2285 to 4204913 , 2286 strand minus , 2287 id 2288 gi 51471135 } , 2289 int { 2290 from 4206534 , 2291 to 4206597 , 2292 strand minus , 2293 id 2294 gi 51471135 } , 2295 int { 2296 from 4206837 , 2297 to 4207064 , 2298 strand minus , 2299 id 2300 gi 51471135 } , 2301 int { 2302 from 4209629 , 2303 to 4209790 , 2304 strand minus , 2305 id 2306 gi 51471135 } , 2307 int { 2308 from 4211627 , 2309 to 4211736 , 2310 strand minus , 2311 id 2312 gi 51471135 } , 2313 int { 2314 from 4211882 , 2315 to 4211996 , 2316 strand minus , 2317 id 2318 gi 51471135 } , 2319 int { 2320 from 4212916 , 2321 to 4213036 , 2322 strand minus , 2323 id 2324 gi 51471135 } , 2325 int { 2326 from 4214705 , 2327 to 4214789 , 2328 strand minus , 2329 id 2330 gi 51471135 } , 2331 int { 2332 from 4215251 , 2333 to 4215419 , 2334 strand minus , 2335 id 2336 gi 51471135 } , 2337 int { 2338 from 4215698 , 2339 to 4215718 , 2340 strand minus , 2341 id 2342 gi 51471135 } , 2343 int { 2344 from 4217543 , 2345 to 4217595 , 2346 strand minus , 2347 id 2348 gi 51471135 } , 2349 int { 2350 from 4217761 , 2351 to 4217920 , 2352 strand minus , 2353 id 2354 gi 51471135 } , 2355 int { 2356 from 4218744 , 2357 to 4218927 , 2358 strand minus , 2359 id 2360 gi 51471135 } , 2361 int { 2362 from 4221148 , 2363 to 4221277 , 2364 strand minus , 2365 id 2366 gi 51471135 } } } , 2367 seqs { 2368 whole 2369 gi 6226959 } , 2370 products { 2371 { 2372 type peptide , 2373 heading "Reference" , 2374 label "precursor" , 2375 accession "NP_000005" , 2376 version 1 , 2377 genomic-coords { 2378 packed-int { 2379 { 2380 from 4173280 , 2381 to 4173296 , 2382 strand minus , 2383 id 2384 gi 51471135 } , 2385 { 2386 from 4173640 , 2387 to 4173681 , 2388 strand minus , 2389 id 2390 gi 51471135 } , 2391 { 2392 from 4174197 , 2393 to 4174299 , 2394 strand minus , 2395 id 2396 gi 51471135 } , 2397 { 2398 from 4175201 , 2399 to 4175269 , 2400 strand minus , 2401 id 2402 gi 51471135 } , 2403 { 2404 from 4175944 , 2405 to 4176034 , 2406 strand minus , 2407 id 2408 gi 51471135 } , 2409 { 2410 from 4177816 , 2411 to 4177943 , 2412 strand minus , 2413 id 2414 gi 51471135 } , 2415 { 2416 from 4178110 , 2417 to 4178328 , 2418 strand minus , 2419 id 2420 gi 51471135 } , 2421 { 2422 from 4180017 , 2423 to 4180240 , 2424 strand minus , 2425 id 2426 gi 51471135 } , 2427 { 2428 from 4182213 , 2429 to 4182393 , 2430 strand minus , 2431 id 2432 gi 51471135 } , 2433 { 2434 from 4182803 , 2435 to 4182877 , 2436 strand minus , 2437 id 2438 gi 51471135 } , 2439 { 2440 from 4183158 , 2441 to 4183314 , 2442 strand minus , 2443 id 2444 gi 51471135 } , 2445 { 2446 from 4184702 , 2447 to 4184789 , 2448 strand minus , 2449 id 2450 gi 51471135 } , 2451 { 2452 from 4185097 , 2453 to 4185273 , 2454 strand minus , 2455 id 2456 gi 51471135 } , 2457 { 2458 from 4185552 , 2459 to 4185635 , 2460 strand minus , 2461 id 2462 gi 51471135 } , 2463 { 2464 from 4194661 , 2465 to 4194712 , 2466 strand minus , 2467 id 2468 gi 51471135 } , 2469 { 2470 from 4195363 , 2471 to 4195484 , 2472 strand minus , 2473 id 2474 gi 51471135 } , 2475 { 2476 from 4195817 , 2477 to 4195943 , 2478 strand minus , 2479 id 2480 gi 51471135 } , 2481 { 2482 from 4196662 , 2483 to 4196890 , 2484 strand minus , 2485 id 2486 gi 51471135 } , 2487 { 2488 from 4198926 , 2489 to 4199040 , 2490 strand minus , 2491 id 2492 gi 51471135 } , 2493 { 2494 from 4200364 , 2495 to 4200475 , 2496 strand minus , 2497 id 2498 gi 51471135 } , 2499 { 2500 from 4200930 , 2501 to 4201091 , 2502 strand minus , 2503 id 2504 gi 51471135 } , 2505 { 2506 from 4203997 , 2507 to 4204146 , 2508 strand minus , 2509 id 2510 gi 51471135 } , 2511 { 2512 from 4204771 , 2513 to 4204913 , 2514 strand minus , 2515 id 2516 gi 51471135 } , 2517 { 2518 from 4206534 , 2519 to 4206597 , 2520 strand minus , 2521 id 2522 gi 51471135 } , 2523 { 2524 from 4206837 , 2525 to 4207064 , 2526 strand minus , 2527 id 2528 gi 51471135 } , 2529 { 2530 from 4209629 , 2531 to 4209790 , 2532 strand minus , 2533 id 2534 gi 51471135 } , 2535 { 2536 from 4211627 , 2537 to 4211736 , 2538 strand minus , 2539 id 2540 gi 51471135 } , 2541 { 2542 from 4211882 , 2543 to 4211996 , 2544 strand minus , 2545 id 2546 gi 51471135 } , 2547 { 2548 from 4212916 , 2549 to 4213036 , 2550 strand minus , 2551 id 2552 gi 51471135 } , 2553 { 2554 from 4214705 , 2555 to 4214789 , 2556 strand minus , 2557 id 2558 gi 51471135 } , 2559 { 2560 from 4215251 , 2561 to 4215419 , 2562 strand minus , 2563 id 2564 gi 51471135 } , 2565 { 2566 from 4215698 , 2567 to 4215718 , 2568 strand minus , 2569 id 2570 gi 51471135 } , 2571 { 2572 from 4217543 , 2573 to 4217595 , 2574 strand minus , 2575 id 2576 gi 51471135 } , 2577 { 2578 from 4217761 , 2579 to 4217920 , 2580 strand minus , 2581 id 2582 gi 51471135 } , 2583 { 2584 from 4218744 , 2585 to 4218927 , 2586 strand minus , 2587 id 2588 gi 51471135 } , 2589 { 2590 from 4221148 , 2591 to 4221233 , 2592 strand minus , 2593 id 2594 gi 51471135 } } } , 2595 seqs { 2596 whole 2597 gi 4557225 } } } } } } } , 2598 properties { 2599 { 2600 type comment , 2601 label "Nomenclature" , 2602 version 0 , 2603 source { 2604 { 2605 anchor "HUGO Gene Nomenclature Committee" } } , 2606 properties { 2607 { 2608 type property , 2609 label "Official Symbol" , 2610 text "A2M" , 2611 version 0 } , 2612 { 2613 type property , 2614 label "Official Full Name" , 2615 text "alpha-2-macroglobulin" , 2616 version 0 } } } , 2617 { 2618 type comment , 2619 heading "GeneOntology" , 2620 version 0 , 2621 source { 2622 { 2623 pre-text "Provided by" , 2624 anchor "GOA" , 2625 url "http://www.ebi.ac.uk/GOA/" } } , 2626 comment { 2627 { 2628 type comment , 2629 label "Function" , 2630 version 0 , 2631 comment { 2632 { 2633 type comment , 2634 version 0 , 2635 refs { 2636 pmid 11435418 } , 2637 source { 2638 { 2639 src { 2640 db "GO" , 2641 tag 2642 id 19899 } , 2643 anchor "enzyme binding" , 2644 post-text "evidence: IPI" } } } , 2645 { 2646 type comment , 2647 version 0 , 2648 refs { 2649 pmid 9714181 } , 2650 source { 2651 { 2652 src { 2653 db "GO" , 2654 tag 2655 id 19966 } , 2656 anchor "interleukin-1 binding" , 2657 post-text "evidence: IDA" } } } , 2658 { 2659 type comment , 2660 version 0 , 2661 refs { 2662 pmid 10880251 } , 2663 source { 2664 { 2665 src { 2666 db "GO" , 2667 tag 2668 id 19959 } , 2669 anchor "interleukin-8 binding" , 2670 post-text "evidence: IPI" } } } , 2671 { 2672 type comment , 2673 version 0 , 2674 source { 2675 { 2676 src { 2677 db "GO" , 2678 tag 2679 id 8320 } , 2680 anchor "protein carrier activity" , 2681 post-text "evidence: NR" } } } , 2682 { 2683 type comment , 2684 version 0 , 2685 source { 2686 { 2687 src { 2688 db "GO" , 2689 tag 2690 id 4867 } , 2691 anchor "serine-type endopeptidase inhibitor activity" , 2692 post-text "evidence: IEA" } } } , 2693 { 2694 type comment , 2695 version 0 , 2696 refs { 2697 pmid 9714181 } , 2698 source { 2699 { 2700 src { 2701 db "GO" , 2702 tag 2703 id 43120 } , 2704 anchor "tumor necrosis factor binding" , 2705 post-text "evidence: IDA" } } } , 2706 { 2707 type comment , 2708 version 0 , 2709 source { 2710 { 2711 src { 2712 db "GO" , 2713 tag 2714 id 17114 } , 2715 anchor "wide-spectrum protease inhibitor activity" , 2716 post-text "evidence: IEA" } } } } } , 2717 { 2718 type comment , 2719 label "Process" , 2720 version 0 , 2721 comment { 2722 { 2723 type comment , 2724 version 0 , 2725 source { 2726 { 2727 src { 2728 db "GO" , 2729 tag 2730 id 6886 } , 2731 anchor "intracellular protein transport" , 2732 post-text "evidence: NR" } } } , 2733 { 2734 type comment , 2735 version 0 , 2736 source { 2737 { 2738 src { 2739 db "GO" , 2740 tag 2741 id 51260 } , 2742 anchor "protein homooligomerization" , 2743 post-text "evidence: NAS" } } } } } , 2744 { 2745 type comment , 2746 label "Component" , 2747 version 0 , 2748 comment { 2749 { 2750 type comment , 2751 version 0 , 2752 refs { 2753 pmid 14718574 } , 2754 source { 2755 { 2756 src { 2757 db "GO" , 2758 tag 2759 id 5576 } , 2760 anchor "extracellular region" , 2761 post-text "evidence: NAS" } } } } } } } } , 2762 homology { 2763 { 2764 type comment , 2765 heading "Mouse, Rat" , 2766 version 0 , 2767 source { 2768 { 2769 src { 2770 db "HomoloGene" , 2771 tag 2772 id 37248 } , 2773 anchor "Map Viewer" , 2774 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=12& 2775MAPS=genes-r-org/rat-chr/human%3A12,genes-r-org/mouse-chr/human%3A12,genes-r-o 2776rg/human-chr12&query=e%3A2[id]+AND+gene[obj_type]&QSTR=a2m&cmd=focus&fill=10" } } } } , 2777 comments { 2778 { 2779 type comment , 2780 heading "LocusTagLink" , 2781 version 0 , 2782 source { 2783 { 2784 src { 2785 db "HGNC" , 2786 tag 2787 id 7 } } } } , 2788 { 2789 type comment , 2790 heading "RefSeq Status" , 2791 label "REVIEWED" , 2792 version 0 } , 2793 { 2794 type comment , 2795 version 0 , 2796 refs { 2797 pmid 15511627 , 2798 pmid 15023809 , 2799 pmid 14760718 , 2800 pmid 14718574 , 2801 pmid 14715656 , 2802 pmid 14678766 , 2803 pmid 14675603 , 2804 pmid 14637088 , 2805 pmid 14506912 , 2806 pmid 12966032 , 2807 pmid 12755687 , 2808 pmid 12755614 , 2809 pmid 12631277 , 2810 pmid 12477932 , 2811 pmid 12221172 , 2812 pmid 12194978 , 2813 pmid 12175343 , 2814 pmid 12062545 , 2815 pmid 12042276 , 2816 pmid 12015318 , 2817 pmid 11916201 , 2818 pmid 11910179 , 2819 pmid 11901360 , 2820 pmid 11823454 , 2821 pmid 11811950 , 2822 pmid 11435418 , 2823 pmid 11162584 , 2824 pmid 11100124 , 2825 pmid 11023837 , 2826 pmid 10880251 , 2827 pmid 10731476 , 2828 pmid 10714547 , 2829 pmid 10652313 , 2830 pmid 10373500 , 2831 pmid 9831625 , 2832 pmid 9724081 , 2833 pmid 9714181 , 2834 pmid 8583572 , 2835 pmid 7680268 , 2836 pmid 7533769 , 2837 pmid 7533162 , 2838 pmid 7519849 , 2839 pmid 6191979 , 2840 pmid 6153632 , 2841 pmid 3289986 , 2842 pmid 2581245 , 2843 pmid 2476070 , 2844 pmid 2460294 , 2845 pmid 2459995 , 2846 pmid 2408344 , 2847 pmid 1707161 , 2848 pmid 1697852 , 2849 pmid 1370808 , 2850 pmid 1281457 , 2851 pmid 89758 } } , 2852 { 2853 type comment , 2854 heading "Phenotypes" , 2855 version 0 , 2856 comment { 2857 { 2858 type phenotype , 2859 text "Alzheimer disease, susceptibility to" , 2860 version 0 , 2861 source { 2862 { 2863 src { 2864 db "MIM" , 2865 tag 2866 id 103950 } , 2867 anchor "MIM: 103950" } } } , 2868 { 2869 type phenotype , 2870 text "Emphysema due to alpha-2-macroglobulin deficiency" , 2871 version 0 , 2872 source { 2873 { 2874 src { 2875 db "MIM" , 2876 tag 2877 id 103950 } , 2878 anchor "MIM: 103950" } } } } } , 2879 { 2880 type comment , 2881 heading "Markers (Sequence Tagged Sites/STS)" , 2882 version 0 , 2883 comment { 2884 { 2885 type comment , 2886 version 0 , 2887 source { 2888 { 2889 src { 2890 db "UniSTS" , 2891 tag 2892 id 25036 } , 2893 anchor "RH1601" , 2894 post-text "(e-PCR)" } } , 2895 comment { 2896 { 2897 type other , 2898 label "Alternate name" , 2899 text "RH44109" , 2900 version 0 } , 2901 { 2902 type other , 2903 label "Alternate name" , 2904 text "stSG1293" , 2905 version 0 } } } , 2906 { 2907 type comment , 2908 version 0 , 2909 source { 2910 { 2911 src { 2912 db "UniSTS" , 2913 tag 2914 id 40245 } , 2915 anchor "SGC31674" , 2916 post-text "(e-PCR)" } } , 2917 comment { 2918 { 2919 type other , 2920 label "Alternate name" , 2921 text "EST130345" , 2922 version 0 } , 2923 { 2924 type other , 2925 label "Alternate name" , 2926 text "RH52474" , 2927 version 0 } , 2928 { 2929 type other , 2930 label "Alternate name" , 2931 text "WI-219" , 2932 version 0 } } } , 2933 { 2934 type comment , 2935 version 0 , 2936 source { 2937 { 2938 src { 2939 db "UniSTS" , 2940 tag 2941 id 46849 } , 2942 anchor "RH11157" , 2943 post-text "(e-PCR)" } } , 2944 comment { 2945 { 2946 type other , 2947 label "Alternate name" , 2948 text "RH44108" , 2949 version 0 } , 2950 { 2951 type other , 2952 label "Alternate name" , 2953 text "stSG1290R" , 2954 version 0 } } } , 2955 { 2956 type comment , 2957 version 0 , 2958 source { 2959 { 2960 src { 2961 db "UniSTS" , 2962 tag 2963 id 95143 } , 2964 anchor "G44356" , 2965 post-text "(e-PCR)" } } , 2966 comment { 2967 { 2968 type other , 2969 label "Alternate name" , 2970 text "WIAF-1430-STS" , 2971 version 0 } } } , 2972 { 2973 type comment , 2974 version 0 , 2975 source { 2976 { 2977 src { 2978 db "UniSTS" , 2979 tag 2980 id 147540 } , 2981 anchor "NoName" , 2982 post-text "(e-PCR)" } } } , 2983 { 2984 type comment , 2985 version 0 , 2986 source { 2987 { 2988 src { 2989 db "UniSTS" , 2990 tag 2991 id 151442 } , 2992 anchor "NoName" , 2993 post-text "(e-PCR)" } } } } } , 2994 { 2995 type comment , 2996 heading "NCBI Reference Sequences (RefSeq)" , 2997 version 0 , 2998 products { 2999 { 3000 type mRNA , 3001 heading "mRNA Sequence" , 3002 accession "NM_000014" , 3003 version 3 , 3004 source { 3005 { 3006 src { 3007 db "Nucleotide" , 3008 tag 3009 id 6226959 } , 3010 anchor "NM_000014" } } , 3011 seqs { 3012 whole 3013 gi 6226959 } , 3014 products { 3015 { 3016 type peptide , 3017 heading "Product" , 3018 accession "NP_000005" , 3019 version 1 , 3020 source { 3021 { 3022 src { 3023 db "Protein" , 3024 tag 3025 id 4557225 } , 3026 anchor "NP_000005" , 3027 post-text "alpha-2-macroglobulin precursor" } } , 3028 seqs { 3029 whole 3030 gi 4557225 } , 3031 comment { 3032 { 3033 type other , 3034 heading "Conserved Domains" , 3035 version 0 , 3036 source { 3037 { 3038 src { 3039 db "PROT_CDD" , 3040 tag 3041 id 4557225 } , 3042 pre-text "(2)" , 3043 anchor "summary" } } , 3044 comment { 3045 { 3046 type other , 3047 version 0 , 3048 source { 3049 { 3050 src { 3051 db "CDD" , 3052 tag 3053 id 5952 } , 3054 anchor "pfam00207: A2M; Alpha-2-macroglobulin family" } } , 3055 comment { 3056 { 3057 type other , 3058 text "Location: 725 - 1463 Blast Score: 2322" , 3059 version 0 } } } , 3060 { 3061 type other , 3062 version 0 , 3063 source { 3064 { 3065 src { 3066 db "CDD" , 3067 tag 3068 id 25832 } , 3069 anchor "pfam01835: A2M_N; Alpha-2-macroglobulin 3070 family N-terminal region" } } , 3071 comment { 3072 { 3073 type other , 3074 text "Location: 21 - 628 Blast Score: 1948" , 3075 version 0 } } } } } } } } , 3076 comment { 3077 { 3078 type other , 3079 heading "Source Sequence" , 3080 version 0 , 3081 source { 3082 { 3083 src { 3084 db "Nucleotide" , 3085 tag 3086 str "M11313" } , 3087 anchor "M11313" } } , 3088 comment { 3089 { 3090 type other , 3091 version 0 } } } } } } } , 3092 { 3093 type comment , 3094 heading "Related Sequences" , 3095 version 0 , 3096 products { 3097 { 3098 type genomic , 3099 heading "Genomic" , 3100 accession "AF349032" , 3101 version 1 , 3102 source { 3103 { 3104 src { 3105 db "Nucleotide" , 3106 tag 3107 id 13661813 } , 3108 anchor "AF349032" } } , 3109 seqs { 3110 whole 3111 gi 13661813 } , 3112 products { 3113 { 3114 type peptide , 3115 accession "AAK38109" , 3116 version 1 , 3117 source { 3118 { 3119 src { 3120 db "Protein" , 3121 tag 3122 id 13661814 } , 3123 anchor "AAK38109" } } , 3124 seqs { 3125 whole 3126 gi 13661814 } } } } , 3127 { 3128 type genomic , 3129 heading "Genomic" , 3130 accession "AF349033" , 3131 version 1 , 3132 source { 3133 { 3134 src { 3135 db "Nucleotide" , 3136 tag 3137 id 13661815 } , 3138 anchor "AF349033" } } , 3139 seqs { 3140 whole 3141 gi 13661815 } , 3142 products { 3143 { 3144 type peptide , 3145 accession "AAK38110" , 3146 version 1 , 3147 source { 3148 { 3149 src { 3150 db "Protein" , 3151 tag 3152 id 13661816 } , 3153 anchor "AAK38110" } } , 3154 seqs { 3155 whole 3156 gi 13661816 } } } } , 3157 { 3158 type genomic , 3159 heading "Genomic" , 3160 accession "X68728" , 3161 version 1 , 3162 source { 3163 { 3164 src { 3165 db "Nucleotide" , 3166 tag 3167 id 450521 } , 3168 anchor "X68728" } } , 3169 seqs { 3170 whole 3171 gi 450521 } , 3172 products { 3173 { 3174 type peptide , 3175 accession "CAA48670" , 3176 version 1 , 3177 source { 3178 { 3179 src { 3180 db "Protein" , 3181 tag 3182 id 825615 } , 3183 anchor "CAA48670" } } , 3184 seqs { 3185 whole 3186 gi 825615 } } } } , 3187 { 3188 type genomic , 3189 heading "Genomic" , 3190 accession "Z11711" , 3191 version 1 , 3192 source { 3193 { 3194 src { 3195 db "Nucleotide" , 3196 tag 3197 id 24760 } , 3198 anchor "Z11711" } } , 3199 seqs { 3200 whole 3201 gi 24760 } , 3202 products { 3203 { 3204 type peptide , 3205 accession "CAA77774" , 3206 version 1 , 3207 source { 3208 { 3209 src { 3210 db "Protein" , 3211 tag 3212 id 24761 } , 3213 anchor "CAA77774" } } , 3214 seqs { 3215 whole 3216 gi 24761 } } } } , 3217 { 3218 type mRNA , 3219 heading "mRNA" , 3220 accession "AB209614" , 3221 version 1 , 3222 source { 3223 { 3224 src { 3225 db "Nucleotide" , 3226 tag 3227 id 62088807 } , 3228 anchor "AB209614" } } , 3229 seqs { 3230 whole 3231 gi 62088807 } , 3232 products { 3233 { 3234 type peptide , 3235 accession "BAD92851" , 3236 version 1 , 3237 source { 3238 { 3239 src { 3240 db "Protein" , 3241 tag 3242 id 62088808 } , 3243 anchor "BAD92851" } } , 3244 seqs { 3245 whole 3246 gi 62088808 } } } } , 3247 { 3248 type mRNA , 3249 heading "mRNA" , 3250 accession "AF109189" , 3251 version 1 , 3252 source { 3253 { 3254 src { 3255 db "Nucleotide" , 3256 tag 3257 id 33337723 } , 3258 anchor "AF109189" } } , 3259 seqs { 3260 whole 3261 gi 33337723 } , 3262 products { 3263 { 3264 type peptide , 3265 accession "AAQ13498" , 3266 version 1 , 3267 source { 3268 { 3269 src { 3270 db "Protein" , 3271 tag 3272 id 33337724 } , 3273 anchor "AAQ13498" } } , 3274 seqs { 3275 whole 3276 gi 33337724 } } } } , 3277 { 3278 type mRNA , 3279 heading "mRNA" , 3280 accession "AY591530" , 3281 version 1 , 3282 source { 3283 { 3284 src { 3285 db "Nucleotide" , 3286 tag 3287 id 46812314 } , 3288 anchor "AY591530" } } , 3289 seqs { 3290 whole 3291 gi 46812314 } , 3292 products { 3293 { 3294 type peptide , 3295 accession "AAT02228" , 3296 version 1 , 3297 source { 3298 { 3299 src { 3300 db "Protein" , 3301 tag 3302 id 46812315 } , 3303 anchor "AAT02228" } } , 3304 seqs { 3305 whole 3306 gi 46812315 } } } } , 3307 { 3308 type mRNA , 3309 heading "mRNA" , 3310 accession "BC026246" , 3311 version 1 , 3312 source { 3313 { 3314 src { 3315 db "Nucleotide" , 3316 tag 3317 id 45708660 } , 3318 anchor "BC026246" } } , 3319 seqs { 3320 whole 3321 gi 45708660 } , 3322 products { 3323 { 3324 type peptide , 3325 accession "AAH26246" , 3326 version 1 , 3327 source { 3328 { 3329 src { 3330 db "Protein" , 3331 tag 3332 id 45708661 } , 3333 anchor "AAH26246" } } , 3334 seqs { 3335 whole 3336 gi 45708661 } } } } , 3337 { 3338 type mRNA , 3339 heading "mRNA" , 3340 accession "BC040071" , 3341 version 1 , 3342 source { 3343 { 3344 src { 3345 db "Nucleotide" , 3346 tag 3347 id 25303945 } , 3348 anchor "BC040071" } } , 3349 seqs { 3350 whole 3351 gi 25303945 } , 3352 products { 3353 { 3354 type peptide , 3355 accession "AAH40071" , 3356 version 1 , 3357 source { 3358 { 3359 src { 3360 db "Protein" , 3361 tag 3362 id 25303946 } , 3363 anchor "AAH40071" } } , 3364 seqs { 3365 whole 3366 gi 25303946 } } } } , 3367 { 3368 type mRNA , 3369 heading "mRNA" , 3370 accession "BX647329" , 3371 version 1 , 3372 source { 3373 { 3374 src { 3375 db "Nucleotide" , 3376 tag 3377 id 34366357 } , 3378 anchor "BX647329" } } , 3379 seqs { 3380 whole 3381 gi 34366357 } , 3382 products { 3383 { 3384 type peptide , 3385 text "None" , 3386 version 0 } } } , 3387 { 3388 type mRNA , 3389 heading "mRNA" , 3390 accession "CR749334" , 3391 version 1 , 3392 source { 3393 { 3394 src { 3395 db "Nucleotide" , 3396 tag 3397 id 51476395 } , 3398 anchor "CR749334" } } , 3399 seqs { 3400 whole 3401 gi 51476395 } , 3402 products { 3403 { 3404 type peptide , 3405 accession "CAH18188" , 3406 version 1 , 3407 source { 3408 { 3409 src { 3410 db "Protein" , 3411 tag 3412 id 51476396 } , 3413 anchor "CAH18188" } } , 3414 seqs { 3415 whole 3416 gi 51476396 } } } } , 3417 { 3418 type mRNA , 3419 heading "mRNA" , 3420 accession "M11313" , 3421 version 1 , 3422 source { 3423 { 3424 src { 3425 db "Nucleotide" , 3426 tag 3427 id 177869 } , 3428 anchor "M11313" } } , 3429 seqs { 3430 whole 3431 gi 177869 } , 3432 products { 3433 { 3434 type peptide , 3435 accession "AAA51551" , 3436 version 1 , 3437 source { 3438 { 3439 src { 3440 db "Protein" , 3441 tag 3442 id 177870 } , 3443 anchor "AAA51551" } } , 3444 seqs { 3445 whole 3446 gi 177870 } } } } , 3447 { 3448 type mRNA , 3449 heading "mRNA" , 3450 accession "M36501" , 3451 version 1 , 3452 source { 3453 { 3454 src { 3455 db "Nucleotide" , 3456 tag 3457 id 177871 } , 3458 anchor "M36501" } } , 3459 seqs { 3460 whole 3461 gi 177871 } , 3462 products { 3463 { 3464 type peptide , 3465 accession "AAA51552" , 3466 version 1 , 3467 source { 3468 { 3469 src { 3470 db "Protein" , 3471 tag 3472 id 177872 } , 3473 anchor "AAA51552" } } , 3474 seqs { 3475 whole 3476 gi 177872 } } } } , 3477 { 3478 type other , 3479 text "None" , 3480 version 0 , 3481 products { 3482 { 3483 type peptide , 3484 accession "P01023" , 3485 version 0 , 3486 source { 3487 { 3488 src { 3489 db "Protein" , 3490 tag 3491 id 112911 } , 3492 anchor "P01023" } } , 3493 seqs { 3494 whole 3495 gi 112911 } } } } } } , 3496 { 3497 type comment , 3498 heading "Additional Links" , 3499 version 0 , 3500 comment { 3501 { 3502 type comment , 3503 version 0 , 3504 source { 3505 { 3506 src { 3507 db "Evidence Viewer" , 3508 tag 3509 str "2" } , 3510 anchor "Evidence Viewer" , 3511 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 3512g=NT_009714.16&gene=A2M&lid=2&from=1979284&to=2027463" } } } , 3513 { 3514 type comment , 3515 version 0 , 3516 source { 3517 { 3518 src { 3519 db "ModelMaker" , 3520 tag 3521 str "2" } , 3522 anchor "ModelMaker" , 3523 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 352406&contig=NT_009714.16&gene=A2M&lid=2" } } } , 3525 { 3526 type comment , 3527 text "UniGene" , 3528 version 0 , 3529 xtra-properties { 3530 { 3531 tag "UNIGENE" , 3532 value "Hs.212838" } } , 3533 source { 3534 { 3535 src { 3536 db "UniGene" , 3537 tag 3538 str "Hs.212838" } , 3539 anchor "Hs.212838" , 3540 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=21 35412838" } } } , 3542 { 3543 type comment , 3544 text "MIM" , 3545 version 0 , 3546 source { 3547 { 3548 src { 3549 db "MIM" , 3550 tag 3551 str "103950" } , 3552 anchor "103950" } } } , 3553 { 3554 type comment , 3555 version 0 , 3556 source { 3557 { 3558 src { 3559 db "HomoloGene" , 3560 tag 3561 str "2" } , 3562 anchor "HomoloGene" , 3563 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 35642[loc]&TAXID=9606" } } } , 3565 { 3566 type comment , 3567 version 0 , 3568 source { 3569 { 3570 src { 3571 db "AceView" , 3572 tag 3573 id 2 } , 3574 anchor "AceView" , 3575 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 3576ocusid&org=9606&l=2" } } } , 3577 { 3578 type comment , 3579 version 0 , 3580 source { 3581 { 3582 src { 3583 db "GDB" , 3584 tag 3585 str "GDB:119639" } } } } , 3586 { 3587 type comment , 3588 version 0 , 3589 source { 3590 { 3591 src { 3592 db "HGMD" , 3593 tag 3594 str "" } , 3595 url "http://www.uwcm.ac.uk/uwcm/mg/search/119639.html" } } } , 3596 { 3597 type comment , 3598 version 0 , 3599 source { 3600 { 3601 src { 3602 db "Ensembl" , 3603 tag 3604 str "" } , 3605 url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=CR749 3606334" } } } , 3607 { 3608 type comment , 3609 version 0 , 3610 source { 3611 { 3612 src { 3613 db "UCSC" , 3614 tag 3615 str "" } , 3616 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position= 3617CR749334" } } } , 3618 { 3619 type comment , 3620 version 0 , 3621 source { 3622 { 3623 src { 3624 db "KEGG" , 3625 tag 3626 str "" } , 3627 url "http://www.genome.ad.jp/dbget-bin/www_bget?hsa:2" } } } , 3628 { 3629 type comment , 3630 text "PharmGKB" , 3631 version 0 , 3632 source { 3633 { 3634 src { 3635 db "PharmGKB" , 3636 tag 3637 str "PA24357" } , 3638 anchor "PA24357" } } } , 3639 { 3640 type comment , 3641 version 0 , 3642 source { 3643 { 3644 src { 3645 db "MGC" , 3646 tag 3647 str "BC040071" } , 3648 anchor "MGC" , 3649 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC040071" } } } } } , 3650 { 3651 type comment , 3652 heading "Pathways" , 3653 version 0 , 3654 comment { 3655 { 3656 type comment , 3657 text "KEGG pathway: Alzheimer's disease" , 3658 version 0 , 3659 source { 3660 { 3661 src { 3662 db "05010" , 3663 tag 3664 str "05010" } , 3665 anchor "05010" , 3666 url "http://www.genome.jp/dbget-bin/show_pathway?hsa05010+2" } } } , 3667 { 3668 type comment , 3669 text "KEGG pathway: Coagulation cascade" , 3670 version 0 , 3671 source { 3672 { 3673 src { 3674 db "04610" , 3675 tag 3676 str "04610" } , 3677 anchor "04610" , 3678 url "http://www.genome.jp/dbget-bin/show_pathway?hsa04610+2" } } } , 3679 { 3680 type comment , 3681 text "KEGG pathway: Complement and coagulation cascades" , 3682 version 0 , 3683 source { 3684 { 3685 src { 3686 db "04610" , 3687 tag 3688 str "04610" } , 3689 anchor "04610" , 3690 url "http://www.genome.jp/dbget-bin/show_pathway?hsa04610+2" } } } , 3691 { 3692 type comment , 3693 text "Reactome: Hemostasis" , 3694 version 0 , 3695 source { 3696 { 3697 anchor "49292" , 3698 url "http://www.reactome.org/cgi-bin/link?SOURCE=UniProt&ID=P010 369923" } } } } } , 3700 { 3701 type generif , 3702 text "an important involvement of alpha2M in regulation of increased 3703 proteolytic activity occurring in multiple sclerosis disease" , 3704 version 0 , 3705 refs { 3706 pmid 15511627 } , 3707 create-date 3708 str "Dec 18 2004 10:01AM" , 3709 update-date 3710 str "Dec 18 2004 1:19PM" } , 3711 { 3712 type generif , 3713 text "alpha2-macroglobulin inhibits human pepsin and gastricsin" , 3714 version 0 , 3715 refs { 3716 pmid 14506912 } , 3717 create-date 3718 str "Oct 7 2003 12:00AM" , 3719 update-date 3720 str "Jul 7 2004 1:36PM" } , 3721 { 3722 type generif , 3723 text "There is a significant genetic association of the 5 bp deletion 3724 and two novel polymorphisms in alpha-2-macroglobulin alpha-2-macroglobulin 3725 precursor with AD" , 3726 version 0 , 3727 refs { 3728 pmid 12966032 } , 3729 create-date 3730 str "Jun 27 2004 5:41PM" , 3731 update-date 3732 str "Jun 27 2004 6:18PM" } , 3733 { 3734 type generif , 3735 text "Alpha2-macroglobulin is a substrate and an endogenous inhibitor 3736 for ADAMTS-4 and ADAMTS-5" , 3737 version 0 , 3738 refs { 3739 pmid 14715656 } , 3740 create-date 3741 str "Jun 14 2004 4:41PM" , 3742 update-date 3743 str "Jun 14 2004 5:44PM" } , 3744 { 3745 type generif , 3746 text "A2M-D allele played a weak Alzheimer disease protective role, and 3747 APOE-E4 and A2M-G alleles might act synergistically in Alzheimer disease risk 3748 for mainland Han Chinese." , 3749 version 0 , 3750 refs { 3751 pmid 14675603 } , 3752 create-date 3753 str "Feb 17 2004 12:00AM" , 3754 update-date 3755 str "Apr 13 2004 1:35PM" } , 3756 { 3757 type generif , 3758 text "Plasma from patients homozygous for the intronic deletion (DD) 3759 showed normal alpha(2)M subunit size, conformation, and proteinase inhibitory 3760 activity. Plasma alpha(2)M from two DD patients showed markedly increased 3761 TGF-beta1 binding." , 3762 version 0 , 3763 refs { 3764 pmid 14678766 } , 3765 create-date 3766 str "Jan 20 2004 12:00AM" , 3767 update-date 3768 str "Mar 7 2004 7:01AM" } , 3769 { 3770 type generif , 3771 text "The presence of MPO-G/G and A2M-Val/Val genotypes synergistically 3772 increased the risk of AD (OR, 25.5; 95% CI, 4.65-139.75)." , 3773 version 0 , 3774 refs { 3775 pmid 15023809 } , 3776 create-date 3777 str "Mar 25 2004 12:00AM" , 3778 update-date 3779 str "Apr 18 2004 7:02AM" } , 3780 { 3781 type generif , 3782 text "alpha2-M deletion polymorphism is probably not associated with 3783 functional deficiencies important in Alzheimer's disease pathology" , 3784 version 0 , 3785 refs { 3786 pmid 14637088 } , 3787 create-date 3788 str "Dec 31 2003 12:00AM" , 3789 update-date 3790 str "Jan 11 2004 7:02AM" } , 3791 { 3792 type generif , 3793 text "FGF-2 and this protein interact at specific binding sites, 3794 involving different FGF-2 sequences." , 3795 version 0 , 3796 refs { 3797 pmid 12755687 } , 3798 create-date 3799 str "Sep 7 2003 12:00AM" , 3800 update-date 3801 str "Sep 28 2003 7:01AM" } , 3802 { 3803 type generif , 3804 text "alpha(2)M-derived peptides target the receptor-binding sequence in 3805 TGF-beta" , 3806 version 0 , 3807 refs { 3808 pmid 12755614 } , 3809 create-date 3810 str "Jun 25 2003 12:00AM" , 3811 update-date 3812 str "Jul 6 2003 7:01AM" } , 3813 { 3814 type generif , 3815 text "These results suggest the possible involvement of cathepsin E in 3816 disruption of the structural and functional integrity of alpha 3817 2-macroglobulin in the endolysosome system." , 3818 version 0 , 3819 refs { 3820 pmid 12631277 } , 3821 create-date 3822 str "May 8 2003 12:00AM" , 3823 update-date 3824 str "May 11 2003 7:01AM" } , 3825 { 3826 type generif , 3827 text "Alpha 2-macroglobulin enhances prothrombin activation and thrombin 3828 potential by inhibiting the anticoagulant protein C/protein S system in cord 3829 and adult plasma." , 3830 version 0 , 3831 refs { 3832 pmid 12062545 } , 3833 create-date 3834 str "Feb 6 2003 12:00AM" , 3835 update-date 3836 str "Aug 17 2003 7:01AM" } , 3837 { 3838 type generif , 3839 text "relationship between serum VEGF levels, alpha(2)M levels and the 3840 development of OHSS in hyperstimulated subjects undergoing IVF" , 3841 version 0 , 3842 refs { 3843 pmid 12042276 } , 3844 create-date 3845 str "Dec 16 2002 12:00AM" , 3846 update-date 3847 str "Feb 2 2003 7:00AM" } , 3848 { 3849 type generif , 3850 text "Genetic association of alpha2-macroglobulin polymorphisms with 3851 Alzheimer's disease" , 3852 version 0 , 3853 refs { 3854 pmid 12221172 } , 3855 create-date 3856 str "Sep 27 2002 12:00AM" , 3857 update-date 3858 str "Oct 7 2002 8:10AM" } , 3859 { 3860 type generif , 3861 text "Genetic association of argyrophilic grain disease with 3862 polymorphisms in alpha-2 macroglobulin." , 3863 version 0 , 3864 refs { 3865 pmid 12175343 } , 3866 create-date 3867 str "Sep 24 2002 12:00AM" , 3868 update-date 3869 str "Oct 7 2002 8:10AM" } , 3870 { 3871 type generif , 3872 text "The three-dimensional structure of the dimer reveals its 3873 structural organization in the tetrameric native and chymotrypsin alpha 3874 2-macroglobulin complexes." , 3875 version 0 , 3876 refs { 3877 pmid 12015318 } , 3878 create-date 3879 str "Sep 5 2002 12:00AM" , 3880 update-date 3881 str "Sep 23 2002 6:27AM" } , 3882 { 3883 type generif , 3884 text "has an important role in the AD-specific neurodegenerative process 3885 but its exon 24 Val-1000-Ile polymorphism is not likely to be associated with 3886 late-onset sporadic AD in the Hungarian population" , 3887 version 0 , 3888 refs { 3889 pmid 11901360 } , 3890 create-date 3891 str "Aug 6 2002 12:00AM" , 3892 update-date 3893 str "Aug 28 2002 6:15PM" } , 3894 { 3895 type generif , 3896 text "REVIEW: binds and neutralizes alfimeprase, which has direct 3897 proteolytic activity against the fibrinogen Aalpha chain" , 3898 version 0 , 3899 refs { 3900 pmid 11910179 } , 3901 create-date 3902 str "Jun 12 2002 12:00AM" , 3903 update-date 3904 str "Sep 7 2003 7:01AM" } , 3905 { 3906 type generif , 3907 text "distinct binding sites mediate interaction with beta-amyloid 3908 peptide and growth factors" , 3909 version 0 , 3910 refs { 3911 pmid 11823454 } , 3912 create-date 3913 str "May 4 2002 12:00AM" , 3914 update-date 3915 str "May 18 2002 6:08AM" } , 3916 { 3917 type generif , 3918 text "Differential binding to ldl receptor related protein" , 3919 version 0 , 3920 refs { 3921 pmid 11811950 } , 3922 create-date 3923 str "Feb 14 2002 12:00AM" , 3924 update-date 3925 str "Mar 4 2002 7:46AM" } , 3926 { 3927 type generif , 3928 heading "HIV-1 protein interactions" , 3929 version 0 , 3930 comment { 3931 { 3932 type generif , 3933 text "Binding of HIV-1 Tat to LRP inhibits neuronal binding, uptake 3934 and degradation of physiological ligands for LRP, including 3935 alpha2-macroglobulin, apolipoprotein E4, amyloid precursor and amyloid 3936 beta-protein" , 3937 version 0 , 3938 refs { 3939 pmid 11100124 } , 3940 comment { 3941 { 3942 type comment , 3943 label "Tat" , 3944 accession "NP_057853" , 3945 version 1 , 3946 source { 3947 { 3948 src { 3949 db "GeneID" , 3950 tag 3951 id 155871 } } } } , 3952 { 3953 type comment , 3954 accession "NP_000005" , 3955 version 1 } } , 3956 create-date 3957 str "May 11 2004 12:48PM" , 3958 update-date 3959 str "May 11 2004 1:10PM" } } } } , 3960 unique-keys { 3961 { 3962 db "LocusID" , 3963 tag 3964 id 2 } , 3965 { 3966 db "MIM" , 3967 tag 3968 id 103950 } } , 3969 xtra-index-terms { 3970 "LOC2" } , 3971 xtra-properties { 3972 { 3973 tag "PROP" , 3974 value "phenotype" } } } 3975Entrezgene ::= { 3976 track-info { 3977 geneid 3 , 3978 status live , 3979 create-date 3980 std { 3981 year 2003 , 3982 month 8 , 3983 day 28 , 3984 hour 20 , 3985 minute 30 , 3986 second 0 } , 3987 update-date 3988 std { 3989 year 2005 , 3990 month 2 , 3991 day 17 , 3992 hour 12 , 3993 minute 9 , 3994 second 0 } } , 3995 type pseudo , 3996 source { 3997 genome genomic , 3998 origin natural , 3999 org { 4000 taxname "Homo sapiens" , 4001 common "human" , 4002 db { 4003 { 4004 db "taxon" , 4005 tag 4006 id 9606 } } , 4007 syn { 4008 "man" } , 4009 orgname { 4010 name 4011 binomial { 4012 genus "Homo" , 4013 species "sapiens" } , 4014 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 4015 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 4016 Hominidae; Homo" , 4017 gcode 1 , 4018 mgcode 2 , 4019 div "PRI" } } , 4020 subtype { 4021 { 4022 subtype chromosome , 4023 name "12" } } } , 4024 gene { 4025 locus "A2MP" , 4026 desc "alpha-2-macroglobulin pseudogene" , 4027 maploc "12p13.3-p12.3" , 4028 locus-tag "HGNC:8" } , 4029 location { 4030 { 4031 display-str "12p13.3-p12.3" , 4032 method 4033 map-type cyto } } , 4034 gene-source { 4035 src "LocusLink" , 4036 src-int 3 , 4037 src-str2 "3" , 4038 gene-display FALSE , 4039 locus-display FALSE , 4040 extra-terms FALSE } , 4041 locus { 4042 { 4043 type genomic , 4044 heading "Reference" , 4045 accession "NC_000012" , 4046 version 9 , 4047 seqs { 4048 int { 4049 from 9275468 , 4050 to 9278174 , 4051 strand minus , 4052 id 4053 gi 51511728 , 4054 fuzz-from 4055 lim lt , 4056 fuzz-to 4057 lim gt } } } , 4058 { 4059 type genomic , 4060 heading "Reference" , 4061 accession "NT_009714" , 4062 version 16 , 4063 seqs { 4064 int { 4065 from 2143175 , 4066 to 2145881 , 4067 strand minus , 4068 id 4069 gi 37543832 , 4070 fuzz-from 4071 lim lt , 4072 fuzz-to 4073 lim gt } } } , 4074 { 4075 type genomic , 4076 heading "Reference" , 4077 accession "NT_086792" , 4078 version 1 , 4079 seqs { 4080 int { 4081 from 4337316 , 4082 to 4340022 , 4083 strand minus , 4084 id 4085 gi 51471135 , 4086 fuzz-from 4087 lim lt , 4088 fuzz-to 4089 lim gt } } } , 4090 { 4091 type genomic , 4092 heading "Reference" , 4093 accession "NG_001067" , 4094 version 1 , 4095 seqs { 4096 int { 4097 from 176 , 4098 to 2880 , 4099 strand plus , 4100 id 4101 gi 20270626 , 4102 fuzz-from 4103 lim lt , 4104 fuzz-to 4105 lim gt } } } } , 4106 properties { 4107 { 4108 type comment , 4109 label "Nomenclature" , 4110 version 0 , 4111 source { 4112 { 4113 anchor "HUGO Gene Nomenclature Committee" } } , 4114 properties { 4115 { 4116 type property , 4117 label "Official Symbol" , 4118 text "A2MP" , 4119 version 0 } , 4120 { 4121 type property , 4122 label "Official Full Name" , 4123 text "alpha-2-macroglobulin pseudogene" , 4124 version 0 } } } } , 4125 comments { 4126 { 4127 type comment , 4128 heading "LocusTagLink" , 4129 version 0 , 4130 source { 4131 { 4132 src { 4133 db "HGNC" , 4134 tag 4135 id 8 } } } } , 4136 { 4137 type comment , 4138 heading "RefSeq Status" , 4139 label "PROVISIONAL" , 4140 version 0 } , 4141 { 4142 type comment , 4143 version 0 , 4144 refs { 4145 pmid 2478422 } } , 4146 { 4147 type comment , 4148 heading "NCBI Reference Sequences (RefSeq)" , 4149 version 0 , 4150 comment { 4151 { 4152 type genomic , 4153 heading "Reference" , 4154 accession "NG_001067" , 4155 version 1 , 4156 source { 4157 { 4158 src { 4159 db "Nucleotide" , 4160 tag 4161 id 20270626 } , 4162 anchor "NG_001067" } } , 4163 seqs { 4164 int { 4165 from 1 , 4166 to 3003 , 4167 strand plus , 4168 id 4169 gi 20270626 } } } } } , 4170 { 4171 type comment , 4172 heading "Related Sequences" , 4173 version 0 , 4174 products { 4175 { 4176 type genomic , 4177 heading "Genomic" , 4178 accession "M24415" , 4179 version 1 , 4180 source { 4181 { 4182 src { 4183 db "Nucleotide" , 4184 tag 4185 id 187575 } , 4186 anchor "M24415" } } , 4187 seqs { 4188 int { 4189 from 177 , 4190 to 2881 , 4191 strand plus , 4192 id 4193 gi 187575 } } , 4194 products { 4195 { 4196 type peptide , 4197 text "None" , 4198 version 0 } } } } } , 4199 { 4200 type comment , 4201 heading "Additional Links" , 4202 version 0 , 4203 comment { 4204 { 4205 type comment , 4206 version 0 , 4207 source { 4208 { 4209 src { 4210 db "Evidence Viewer" , 4211 tag 4212 str "3" } , 4213 anchor "Evidence Viewer" , 4214 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 4215g=NT_009714.16&gene=A2MP&lid=3&from=2143176&to=2145882" } } } , 4216 { 4217 type comment , 4218 version 0 , 4219 source { 4220 { 4221 src { 4222 db "ModelMaker" , 4223 tag 4224 str "3" } , 4225 anchor "ModelMaker" , 4226 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 422706&contig=NT_009714.16&gene=A2MP&lid=3" } } } , 4228 { 4229 type comment , 4230 version 0 , 4231 source { 4232 { 4233 src { 4234 db "AceView" , 4235 tag 4236 id 3 } , 4237 anchor "AceView" , 4238 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 4239ocusid&org=9606&l=3" } } } , 4240 { 4241 type comment , 4242 version 0 , 4243 source { 4244 { 4245 src { 4246 db "GDB" , 4247 tag 4248 str "GDB:128103" } } } } } } } , 4249 unique-keys { 4250 { 4251 db "LocusID" , 4252 tag 4253 id 3 } } , 4254 xtra-index-terms { 4255 "LOC3" } } 4256Entrezgene ::= { 4257 track-info { 4258 geneid 4 , 4259 status discontinued , 4260 create-date 4261 std { 4262 year 2003 , 4263 month 8 , 4264 day 28 , 4265 hour 20 , 4266 minute 30 , 4267 second 0 } , 4268 update-date 4269 std { 4270 year 2005 , 4271 month 2 , 4272 day 17 , 4273 hour 12 , 4274 minute 9 , 4275 second 0 } } , 4276 type protein-coding , 4277 source { 4278 genome genomic , 4279 origin natural , 4280 org { 4281 taxname "Homo sapiens" , 4282 common "human" , 4283 db { 4284 { 4285 db "taxon" , 4286 tag 4287 id 9606 } } , 4288 syn { 4289 "man" } , 4290 orgname { 4291 name 4292 binomial { 4293 genus "Homo" , 4294 species "sapiens" } , 4295 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 4296 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 4297 Hominidae; Homo" , 4298 gcode 1 , 4299 mgcode 2 , 4300 div "PRI" } } , 4301 subtype { 4302 { 4303 subtype chromosome , 4304 name "1" } } } , 4305 gene { 4306 desc "adenovirus-12 chromosome modification site 1C" , 4307 maploc "1q42-q43" , 4308 syn { 4309 "A12M1" } } , 4310 prot { 4311 name { 4312 "adenovirus-12 chromosome modification site 1C" , 4313 "Adenovirus-12 chromosome modification site-1q1" } } , 4314 location { 4315 { 4316 display-str "1q42-q43" , 4317 method 4318 map-type cyto } } , 4319 gene-source { 4320 src "LocusLink" , 4321 src-int 4 , 4322 src-str2 "4" , 4323 gene-display FALSE , 4324 locus-display FALSE , 4325 extra-terms FALSE } , 4326 locus { 4327 { 4328 type genomic , 4329 version 0 } } , 4330 comments { 4331 { 4332 type comment , 4333 heading "RefSeq Status" , 4334 label "WITHDRAWN" , 4335 version 0 } , 4336 { 4337 type comment , 4338 heading "Additional Links" , 4339 version 0 , 4340 comment { 4341 { 4342 type comment , 4343 version 0 , 4344 source { 4345 { 4346 src { 4347 db "GDB" , 4348 tag 4349 str "GDB:118950" } } } } } } } , 4350 unique-keys { 4351 { 4352 db "LocusID" , 4353 tag 4354 id 4 } } , 4355 xtra-index-terms { 4356 "LOC4" } } 4357Entrezgene ::= { 4358 track-info { 4359 geneid 5 , 4360 status discontinued , 4361 create-date 4362 std { 4363 year 2003 , 4364 month 8 , 4365 day 28 , 4366 hour 20 , 4367 minute 30 , 4368 second 0 } , 4369 update-date 4370 std { 4371 year 2005 , 4372 month 2 , 4373 day 17 , 4374 hour 12 , 4375 minute 9 , 4376 second 0 } } , 4377 type protein-coding , 4378 source { 4379 genome genomic , 4380 origin natural , 4381 org { 4382 taxname "Homo sapiens" , 4383 common "human" , 4384 db { 4385 { 4386 db "taxon" , 4387 tag 4388 id 9606 } } , 4389 syn { 4390 "man" } , 4391 orgname { 4392 name 4393 binomial { 4394 genus "Homo" , 4395 species "sapiens" } , 4396 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 4397 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 4398 Hominidae; Homo" , 4399 gcode 1 , 4400 mgcode 2 , 4401 div "PRI" } } , 4402 subtype { 4403 { 4404 subtype chromosome , 4405 name "1" } } } , 4406 gene { 4407 desc "adenovirus-12 chromosome modification site 1A" , 4408 maploc "1p36" , 4409 syn { 4410 "A12M2" } } , 4411 prot { 4412 name { 4413 "adenovirus-12 chromosome modification site 1A" , 4414 "Adenovirus-12 chromosome modification site-1p" } } , 4415 location { 4416 { 4417 display-str "1p36" , 4418 method 4419 map-type cyto } } , 4420 gene-source { 4421 src "LocusLink" , 4422 src-int 5 , 4423 src-str2 "5" , 4424 gene-display FALSE , 4425 locus-display FALSE , 4426 extra-terms FALSE } , 4427 locus { 4428 { 4429 type genomic , 4430 version 0 } } , 4431 comments { 4432 { 4433 type comment , 4434 heading "RefSeq Status" , 4435 label "WITHDRAWN" , 4436 version 0 } , 4437 { 4438 type comment , 4439 heading "Additional Links" , 4440 version 0 , 4441 comment { 4442 { 4443 type comment , 4444 version 0 , 4445 source { 4446 { 4447 src { 4448 db "GDB" , 4449 tag 4450 str "GDB:118951" } } } } } } } , 4451 unique-keys { 4452 { 4453 db "LocusID" , 4454 tag 4455 id 5 } } , 4456 xtra-index-terms { 4457 "LOC5" } } 4458Entrezgene ::= { 4459 track-info { 4460 geneid 6 , 4461 status discontinued , 4462 create-date 4463 std { 4464 year 2003 , 4465 month 8 , 4466 day 28 , 4467 hour 20 , 4468 minute 30 , 4469 second 0 } , 4470 update-date 4471 std { 4472 year 2005 , 4473 month 2 , 4474 day 17 , 4475 hour 12 , 4476 minute 9 , 4477 second 0 } } , 4478 type protein-coding , 4479 source { 4480 genome genomic , 4481 origin natural , 4482 org { 4483 taxname "Homo sapiens" , 4484 common "human" , 4485 db { 4486 { 4487 db "taxon" , 4488 tag 4489 id 9606 } } , 4490 syn { 4491 "man" } , 4492 orgname { 4493 name 4494 binomial { 4495 genus "Homo" , 4496 species "sapiens" } , 4497 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 4498 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 4499 Hominidae; Homo" , 4500 gcode 1 , 4501 mgcode 2 , 4502 div "PRI" } } , 4503 subtype { 4504 { 4505 subtype chromosome , 4506 name "1" } } } , 4507 gene { 4508 desc "adenovirus-12 chromosome modification site 1B" , 4509 maploc "1q21" , 4510 syn { 4511 "A12M3" } } , 4512 prot { 4513 name { 4514 "adenovirus-12 chromosome modification site 1B" , 4515 "Adenovirus-12 chromosome modification site-1q2" } } , 4516 location { 4517 { 4518 display-str "1q21" , 4519 method 4520 map-type cyto } } , 4521 gene-source { 4522 src "LocusLink" , 4523 src-int 6 , 4524 src-str2 "6" , 4525 gene-display FALSE , 4526 locus-display FALSE , 4527 extra-terms FALSE } , 4528 locus { 4529 { 4530 type genomic , 4531 version 0 } } , 4532 comments { 4533 { 4534 type comment , 4535 heading "RefSeq Status" , 4536 label "WITHDRAWN" , 4537 version 0 } , 4538 { 4539 type comment , 4540 heading "Additional Links" , 4541 version 0 , 4542 comment { 4543 { 4544 type comment , 4545 version 0 , 4546 source { 4547 { 4548 src { 4549 db "GDB" , 4550 tag 4551 str "GDB:118952" } } } } } } } , 4552 unique-keys { 4553 { 4554 db "LocusID" , 4555 tag 4556 id 6 } } , 4557 xtra-index-terms { 4558 "LOC6" } } 4559Entrezgene ::= { 4560 track-info { 4561 geneid 7 , 4562 status discontinued , 4563 create-date 4564 std { 4565 year 2003 , 4566 month 8 , 4567 day 28 , 4568 hour 20 , 4569 minute 30 , 4570 second 0 } , 4571 update-date 4572 std { 4573 year 2005 , 4574 month 2 , 4575 day 17 , 4576 hour 12 , 4577 minute 9 , 4578 second 0 } } , 4579 type protein-coding , 4580 source { 4581 genome genomic , 4582 origin natural , 4583 org { 4584 taxname "Homo sapiens" , 4585 common "human" , 4586 db { 4587 { 4588 db "taxon" , 4589 tag 4590 id 9606 } } , 4591 syn { 4592 "man" } , 4593 orgname { 4594 name 4595 binomial { 4596 genus "Homo" , 4597 species "sapiens" } , 4598 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 4599 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 4600 Hominidae; Homo" , 4601 gcode 1 , 4602 mgcode 2 , 4603 div "PRI" } } , 4604 subtype { 4605 { 4606 subtype chromosome , 4607 name "17" } } } , 4608 gene { 4609 desc "adenovirus-12 chromosome modification site 17" , 4610 maploc "17q21-q22" , 4611 syn { 4612 "A12M4" } } , 4613 prot { 4614 name { 4615 "adenovirus-12 chromosome modification site 17" } } , 4616 location { 4617 { 4618 display-str "17q21-q22" , 4619 method 4620 map-type cyto } } , 4621 gene-source { 4622 src "LocusLink" , 4623 src-int 7 , 4624 src-str2 "7" , 4625 gene-display FALSE , 4626 locus-display FALSE , 4627 extra-terms FALSE } , 4628 locus { 4629 { 4630 type genomic , 4631 version 0 } } , 4632 comments { 4633 { 4634 type comment , 4635 heading "RefSeq Status" , 4636 label "WITHDRAWN" , 4637 version 0 } , 4638 { 4639 type comment , 4640 heading "Additional Links" , 4641 version 0 , 4642 comment { 4643 { 4644 type comment , 4645 version 0 , 4646 source { 4647 { 4648 src { 4649 db "GDB" , 4650 tag 4651 str "GDB:118953" } } } } } } } , 4652 unique-keys { 4653 { 4654 db "LocusID" , 4655 tag 4656 id 7 } } , 4657 xtra-index-terms { 4658 "LOC7" } } 4659Entrezgene ::= { 4660 track-info { 4661 geneid 8 , 4662 status live , 4663 create-date 4664 std { 4665 year 2003 , 4666 month 8 , 4667 day 28 , 4668 hour 20 , 4669 minute 30 , 4670 second 0 } , 4671 update-date 4672 std { 4673 year 2005 , 4674 month 3 , 4675 day 16 , 4676 hour 16 , 4677 minute 24 , 4678 second 0 } } , 4679 type unknown , 4680 source { 4681 genome genomic , 4682 origin natural , 4683 org { 4684 taxname "Homo sapiens" , 4685 common "human" , 4686 db { 4687 { 4688 db "taxon" , 4689 tag 4690 id 9606 } } , 4691 syn { 4692 "man" } , 4693 orgname { 4694 name 4695 binomial { 4696 genus "Homo" , 4697 species "sapiens" } , 4698 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 4699 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 4700 Hominidae; Homo" , 4701 gcode 1 , 4702 mgcode 2 , 4703 div "PRI" } } , 4704 subtype { 4705 { 4706 subtype chromosome , 4707 name "11" } } } , 4708 gene { 4709 locus "AA" , 4710 desc "atrophia areata, peripapillary chorioretinal degeneration" , 4711 maploc "11p15" , 4712 db { 4713 { 4714 db "MIM" , 4715 tag 4716 id 108985 } } , 4717 locus-tag "HGNC:11" } , 4718 location { 4719 { 4720 display-str "11p15" , 4721 method 4722 map-type cyto } } , 4723 gene-source { 4724 src "LocusLink" , 4725 src-int 8 , 4726 src-str2 "8" , 4727 gene-display FALSE , 4728 locus-display FALSE , 4729 extra-terms FALSE } , 4730 locus { 4731 { 4732 type genomic , 4733 version 0 } } , 4734 properties { 4735 { 4736 type comment , 4737 label "Nomenclature" , 4738 version 0 , 4739 source { 4740 { 4741 anchor "HUGO Gene Nomenclature Committee" } } , 4742 properties { 4743 { 4744 type property , 4745 label "Official Symbol" , 4746 text "AA" , 4747 version 0 } , 4748 { 4749 type property , 4750 label "Official Full Name" , 4751 text "atrophia areata, peripapillary chorioretinal degeneration" , 4752 version 0 } } } , 4753 { 4754 type property , 4755 label "Property" , 4756 text "phenotype only" , 4757 version 0 } } , 4758 comments { 4759 { 4760 type comment , 4761 heading "LocusTagLink" , 4762 version 0 , 4763 source { 4764 { 4765 src { 4766 db "HGNC" , 4767 tag 4768 id 11 } } } } , 4769 { 4770 type comment , 4771 version 0 , 4772 refs { 4773 pmid 7795606 } } , 4774 { 4775 type comment , 4776 heading "Phenotypes" , 4777 version 0 , 4778 comment { 4779 { 4780 type phenotype , 4781 text "Atrophia areata" , 4782 version 0 , 4783 source { 4784 { 4785 src { 4786 db "MIM" , 4787 tag 4788 id 108985 } , 4789 anchor "MIM: 108985" } } } , 4790 { 4791 type phenotype , 4792 label "AA" , 4793 text "atrophia areata, peripapillary chorioretinal degeneration" , 4794 version 0 , 4795 source { 4796 { 4797 src { 4798 db "HGNC" , 4799 tag 4800 id 11 } , 4801 anchor "HGNC:11" } } } } } , 4802 { 4803 type comment , 4804 heading "Markers (Sequence Tagged Sites/STS)" , 4805 version 0 , 4806 comment { 4807 { 4808 type comment , 4809 version 0 , 4810 source { 4811 { 4812 src { 4813 db "UniSTS" , 4814 tag 4815 id 31863 } , 4816 anchor "D11S902" , 4817 post-text "(e-PCR)" } } , 4818 comment { 4819 { 4820 type other , 4821 label "Alternate name" , 4822 text "072YD3" , 4823 version 0 } , 4824 { 4825 type other , 4826 label "Alternate name" , 4827 text "AFM072yd3" , 4828 version 0 } , 4829 { 4830 type other , 4831 label "Alternate name" , 4832 text "GDB:187919" , 4833 version 0 } , 4834 { 4835 type other , 4836 label "Alternate name" , 4837 text "HS072YD3" , 4838 version 0 } , 4839 { 4840 type other , 4841 label "Alternate name" , 4842 text "RH15041" , 4843 version 0 } , 4844 { 4845 type other , 4846 label "Alternate name" , 4847 text "RH3044" , 4848 version 0 } , 4849 { 4850 type other , 4851 label "Alternate name" , 4852 text "RH51860" , 4853 version 0 } } } , 4854 { 4855 type comment , 4856 version 0 , 4857 source { 4858 { 4859 src { 4860 db "UniSTS" , 4861 tag 4862 id 31863 } , 4863 anchor "D11S902 (flanking)" } } , 4864 comment { 4865 { 4866 type other , 4867 label "Alternate name" , 4868 text "072YD3" , 4869 version 0 } , 4870 { 4871 type other , 4872 label "Alternate name" , 4873 text "AFM072yd3" , 4874 version 0 } , 4875 { 4876 type other , 4877 label "Alternate name" , 4878 text "GDB:187919" , 4879 version 0 } , 4880 { 4881 type other , 4882 label "Alternate name" , 4883 text "HS072YD3" , 4884 version 0 } , 4885 { 4886 type other , 4887 label "Alternate name" , 4888 text "RH15041" , 4889 version 0 } , 4890 { 4891 type other , 4892 label "Alternate name" , 4893 text "RH3044" , 4894 version 0 } , 4895 { 4896 type other , 4897 label "Alternate name" , 4898 text "RH51860" , 4899 version 0 } } } , 4900 { 4901 type comment , 4902 version 0 , 4903 source { 4904 { 4905 src { 4906 db "UniSTS" , 4907 tag 4908 id 67612 } , 4909 anchor "D11S1323" , 4910 post-text "(e-PCR)" } } , 4911 comment { 4912 { 4913 type other , 4914 label "Alternate name" , 4915 text "AFM248xf9" , 4916 version 0 } , 4917 { 4918 type other , 4919 label "Alternate name" , 4920 text "RH31202" , 4921 version 0 } , 4922 { 4923 type other , 4924 label "Alternate name" , 4925 text "RH73986" , 4926 version 0 } , 4927 { 4928 type other , 4929 label "Alternate name" , 4930 text "SHGC-2070" , 4931 version 0 } } } , 4932 { 4933 type comment , 4934 version 0 , 4935 source { 4936 { 4937 src { 4938 db "UniSTS" , 4939 tag 4940 id 67612 } , 4941 anchor "D11S1323 (flanking)" } } , 4942 comment { 4943 { 4944 type other , 4945 label "Alternate name" , 4946 text "AFM248xf9" , 4947 version 0 } , 4948 { 4949 type other , 4950 label "Alternate name" , 4951 text "RH31202" , 4952 version 0 } , 4953 { 4954 type other , 4955 label "Alternate name" , 4956 text "RH73986" , 4957 version 0 } , 4958 { 4959 type other , 4960 label "Alternate name" , 4961 text "SHGC-2070" , 4962 version 0 } } } } } , 4963 { 4964 type comment , 4965 heading "Additional Links" , 4966 version 0 , 4967 comment { 4968 { 4969 type comment , 4970 text "MIM" , 4971 version 0 , 4972 source { 4973 { 4974 src { 4975 db "MIM" , 4976 tag 4977 str "108985" } , 4978 anchor "108985" } } } , 4979 { 4980 type comment , 4981 version 0 , 4982 source { 4983 { 4984 src { 4985 db "GDB" , 4986 tag 4987 str "GDB:568984" } } } } } } } , 4988 unique-keys { 4989 { 4990 db "LocusID" , 4991 tag 4992 id 8 } , 4993 { 4994 db "MIM" , 4995 tag 4996 id 108985 } } , 4997 xtra-index-terms { 4998 "LOC8" } , 4999 xtra-properties { 5000 { 5001 tag "PROP" , 5002 value "phenotype" } , 5003 { 5004 tag "PROP" , 5005 value "phenotype only" } } } 5006Entrezgene ::= { 5007 track-info { 5008 geneid 9 , 5009 status live , 5010 create-date 5011 std { 5012 year 2003 , 5013 month 8 , 5014 day 28 , 5015 hour 20 , 5016 minute 30 , 5017 second 0 } , 5018 update-date 5019 std { 5020 year 2005 , 5021 month 4 , 5022 day 15 , 5023 hour 9 , 5024 minute 40 , 5025 second 0 } } , 5026 type protein-coding , 5027 source { 5028 genome genomic , 5029 origin natural , 5030 org { 5031 taxname "Homo sapiens" , 5032 common "human" , 5033 db { 5034 { 5035 db "taxon" , 5036 tag 5037 id 9606 } } , 5038 syn { 5039 "man" } , 5040 orgname { 5041 name 5042 binomial { 5043 genus "Homo" , 5044 species "sapiens" } , 5045 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 5046 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 5047 Hominidae; Homo" , 5048 gcode 1 , 5049 mgcode 2 , 5050 div "PRI" } } , 5051 subtype { 5052 { 5053 subtype chromosome , 5054 name "8" } } } , 5055 gene { 5056 locus "NAT1" , 5057 desc "N-acetyltransferase 1 (arylamine N-acetyltransferase)" , 5058 maploc "8p23.1-p21.3" , 5059 db { 5060 { 5061 db "MIM" , 5062 tag 5063 id 108345 } } , 5064 syn { 5065 "AAC1" } , 5066 locus-tag "HGNC:7645" } , 5067 prot { 5068 name { 5069 "N-acetyltransferase 1" , 5070 "arylamine N-acetyltransferase 1" , 5071 "arylamide acetylase 1 (N-acetyltransferase 1)" } } , 5072 location { 5073 { 5074 display-str "8p23.1-p21.3" , 5075 method 5076 map-type cyto } } , 5077 gene-source { 5078 src "LocusLink" , 5079 src-int 9 , 5080 src-str2 "9" , 5081 gene-display FALSE , 5082 locus-display FALSE , 5083 extra-terms FALSE } , 5084 locus { 5085 { 5086 type genomic , 5087 heading "Reference" , 5088 accession "NC_000008" , 5089 version 9 , 5090 seqs { 5091 int { 5092 from 18111894 , 5093 to 18125099 , 5094 strand plus , 5095 id 5096 gi 51511724 } } , 5097 products { 5098 { 5099 type mRNA , 5100 heading "Reference" , 5101 accession "NM_000662" , 5102 version 4 , 5103 genomic-coords { 5104 mix { 5105 int { 5106 from 18111894 , 5107 to 18111968 , 5108 strand plus , 5109 id 5110 gi 51511724 } , 5111 int { 5112 from 18121199 , 5113 to 18121277 , 5114 strand plus , 5115 id 5116 gi 51511724 } , 5117 int { 5118 from 18123830 , 5119 to 18125099 , 5120 strand plus , 5121 id 5122 gi 51511724 } } } , 5123 seqs { 5124 whole 5125 gi 42741670 } , 5126 products { 5127 { 5128 type peptide , 5129 heading "Reference" , 5130 accession "NP_000653" , 5131 version 3 , 5132 genomic-coords { 5133 int { 5134 from 18123836 , 5135 to 18124708 , 5136 strand plus , 5137 id 5138 gi 51511724 } } , 5139 seqs { 5140 whole 5141 gi 42741671 } , 5142 comment { 5143 { 5144 type property , 5145 label "EC" , 5146 text "2.3.1.5" , 5147 version 0 , 5148 xtra-properties { 5149 { 5150 tag "EC" , 5151 value "2.3.1.5" } } } } } } } } } , 5152 { 5153 type genomic , 5154 heading "Reference" , 5155 accession "NT_030737" , 5156 version 9 , 5157 seqs { 5158 int { 5159 from 5912542 , 5160 to 5925747 , 5161 strand plus , 5162 id 5163 gi 51466871 } } , 5164 products { 5165 { 5166 type mRNA , 5167 heading "Reference" , 5168 accession "NM_000662" , 5169 version 4 , 5170 genomic-coords { 5171 mix { 5172 int { 5173 from 5912542 , 5174 to 5912616 , 5175 strand plus , 5176 id 5177 gi 51466871 } , 5178 int { 5179 from 5921847 , 5180 to 5921925 , 5181 strand plus , 5182 id 5183 gi 51466871 } , 5184 int { 5185 from 5924478 , 5186 to 5925747 , 5187 strand plus , 5188 id 5189 gi 51466871 } } } , 5190 seqs { 5191 whole 5192 gi 42741670 } , 5193 products { 5194 { 5195 type peptide , 5196 heading "Reference" , 5197 accession "NP_000653" , 5198 version 3 , 5199 genomic-coords { 5200 int { 5201 from 5924484 , 5202 to 5925356 , 5203 strand plus , 5204 id 5205 gi 51466871 } } , 5206 seqs { 5207 whole 5208 gi 42741671 } , 5209 comment { 5210 { 5211 type property , 5212 label "EC" , 5213 text "2.3.1.5" , 5214 version 0 , 5215 xtra-properties { 5216 { 5217 tag "EC" , 5218 value "2.3.1.5" } } } } } } } } } , 5219 { 5220 type genomic , 5221 heading "Reference" , 5222 accession "NT_086740" , 5223 version 1 , 5224 seqs { 5225 int { 5226 from 5593338 , 5227 to 5606579 , 5228 strand plus , 5229 id 5230 gi 51467159 } } , 5231 products { 5232 { 5233 type mRNA , 5234 heading "Reference" , 5235 accession "NM_000662" , 5236 version 4 , 5237 genomic-coords { 5238 mix { 5239 int { 5240 from 5593338 , 5241 to 5593412 , 5242 strand plus , 5243 id 5244 gi 51467159 } , 5245 int { 5246 from 5602680 , 5247 to 5602758 , 5248 strand plus , 5249 id 5250 gi 51467159 } , 5251 int { 5252 from 5605310 , 5253 to 5606579 , 5254 strand plus , 5255 id 5256 gi 51467159 } } } , 5257 seqs { 5258 whole 5259 gi 42741670 } , 5260 products { 5261 { 5262 type peptide , 5263 heading "Reference" , 5264 accession "NP_000653" , 5265 version 3 , 5266 genomic-coords { 5267 int { 5268 from 5605316 , 5269 to 5606188 , 5270 strand plus , 5271 id 5272 gi 51467159 } } , 5273 seqs { 5274 whole 5275 gi 42741671 } , 5276 comment { 5277 { 5278 type property , 5279 label "EC" , 5280 text "2.3.1.5" , 5281 version 0 , 5282 xtra-properties { 5283 { 5284 tag "EC" , 5285 value "2.3.1.5" } } } } } } } } } } , 5286 properties { 5287 { 5288 type comment , 5289 label "Nomenclature" , 5290 version 0 , 5291 source { 5292 { 5293 anchor "HUGO Gene Nomenclature Committee" } } , 5294 properties { 5295 { 5296 type property , 5297 label "Official Symbol" , 5298 text "NAT1" , 5299 version 0 } , 5300 { 5301 type property , 5302 label "Official Full Name" , 5303 text "N-acetyltransferase 1 (arylamine N-acetyltransferase)" , 5304 version 0 } } } , 5305 { 5306 type comment , 5307 heading "GeneOntology" , 5308 version 0 , 5309 source { 5310 { 5311 pre-text "Provided by" , 5312 anchor "GOA" , 5313 url "http://www.ebi.ac.uk/GOA/" } } , 5314 comment { 5315 { 5316 type comment , 5317 label "Function" , 5318 version 0 , 5319 comment { 5320 { 5321 type comment , 5322 version 0 , 5323 source { 5324 { 5325 src { 5326 db "GO" , 5327 tag 5328 id 16407 } , 5329 anchor "acetyltransferase activity" , 5330 post-text "evidence: IEA" } } } , 5331 { 5332 type comment , 5333 version 0 , 5334 refs { 5335 pmid 10908296 } , 5336 source { 5337 { 5338 src { 5339 db "GO" , 5340 tag 5341 id 4060 } , 5342 anchor "arylamine N-acetyltransferase activity" , 5343 post-text "evidence: TAS" } } } , 5344 { 5345 type comment , 5346 version 0 , 5347 source { 5348 { 5349 src { 5350 db "GO" , 5351 tag 5352 id 16740 } , 5353 anchor "transferase activity" , 5354 post-text "evidence: IEA" } } } } } , 5355 { 5356 type comment , 5357 label "Process" , 5358 version 0 , 5359 comment { 5360 { 5361 type comment , 5362 version 0 , 5363 source { 5364 { 5365 src { 5366 db "GO" , 5367 tag 5368 id 8152 } , 5369 anchor "metabolism" , 5370 post-text "evidence: IEA" } } } } } } } } , 5371 homology { 5372 { 5373 type comment , 5374 heading "Mouse, Rat" , 5375 version 0 , 5376 source { 5377 { 5378 src { 5379 db "HomoloGene" , 5380 tag 5381 id 37329 } , 5382 anchor "Map Viewer" , 5383 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=8&M 5384APS=genes-r-org/rat-chr/human%3A8,genes-r-org/mouse-chr/human%3A8,genes-r-org/ 5385human-chr8&query=e%3A9[id]+AND+gene[obj_type]&QSTR=nat1&cmd=focus&fill=10" } } } } , 5386 comments { 5387 { 5388 type comment , 5389 heading "LocusTagLink" , 5390 version 0 , 5391 source { 5392 { 5393 src { 5394 db "HGNC" , 5395 tag 5396 id 7645 } } } } , 5397 { 5398 type comment , 5399 heading "RefSeq Status" , 5400 label "VALIDATED" , 5401 version 0 } , 5402 { 5403 type comment , 5404 version 0 , 5405 refs { 5406 pmid 15487985 , 5407 pmid 15320760 , 5408 pmid 15226672 , 5409 pmid 15039438 , 5410 pmid 14705222 , 5411 pmid 14672957 , 5412 pmid 14608357 , 5413 pmid 14517345 , 5414 pmid 12946272 , 5415 pmid 12902152 , 5416 pmid 12888564 , 5417 pmid 12860276 , 5418 pmid 12832400 , 5419 pmid 12692115 , 5420 pmid 12682333 , 5421 pmid 12485520 , 5422 pmid 12477932 , 5423 pmid 12355549 , 5424 pmid 12052143 , 5425 pmid 12037388 , 5426 pmid 11955677 , 5427 pmid 11955676 , 5428 pmid 11927838 , 5429 pmid 11470991 , 5430 pmid 10908296 , 5431 pmid 10862520 , 5432 pmid 10767335 , 5433 pmid 9168895 , 5434 pmid 8110178 , 5435 pmid 7773298 , 5436 pmid 2340091 , 5437 pmid 1968463 } } , 5438 { 5439 type comment , 5440 heading "Markers (Sequence Tagged Sites/STS)" , 5441 version 0 , 5442 comment { 5443 { 5444 type comment , 5445 version 0 , 5446 source { 5447 { 5448 src { 5449 db "UniSTS" , 5450 tag 5451 id 24445 } , 5452 anchor "STS-R79401" , 5453 post-text "(e-PCR)" } } , 5454 comment { 5455 { 5456 type other , 5457 label "Alternate name" , 5458 text "RH40594" , 5459 version 0 } , 5460 { 5461 type other , 5462 label "Alternate name" , 5463 text "sts-R79401" , 5464 version 0 } } } , 5465 { 5466 type comment , 5467 version 0 , 5468 source { 5469 { 5470 src { 5471 db "UniSTS" , 5472 tag 5473 id 57372 } , 5474 anchor "STS-D90041" , 5475 post-text "(e-PCR)" } } , 5476 comment { 5477 { 5478 type other , 5479 label "Alternate name" , 5480 text "RH75822" , 5481 version 0 } , 5482 { 5483 type other , 5484 label "Alternate name" , 5485 text "sts-D90041" , 5486 version 0 } } } , 5487 { 5488 type comment , 5489 version 0 , 5490 source { 5491 { 5492 src { 5493 db "UniSTS" , 5494 tag 5495 id 63787 } , 5496 anchor "RH70671" , 5497 post-text "(e-PCR)" } } , 5498 comment { 5499 { 5500 type other , 5501 label "Alternate name" , 5502 text "U52007" , 5503 version 0 } } } , 5504 { 5505 type comment , 5506 version 0 , 5507 source { 5508 { 5509 src { 5510 db "UniSTS" , 5511 tag 5512 id 271536 } , 5513 anchor "PMC165273P2" , 5514 post-text "(e-PCR)" } } } } } , 5515 { 5516 type comment , 5517 heading "NCBI Reference Sequences (RefSeq)" , 5518 version 0 , 5519 products { 5520 { 5521 type mRNA , 5522 heading "mRNA Sequence" , 5523 accession "NM_000662" , 5524 version 4 , 5525 source { 5526 { 5527 src { 5528 db "Nucleotide" , 5529 tag 5530 id 42741670 } , 5531 anchor "NM_000662" } } , 5532 seqs { 5533 whole 5534 gi 42741670 } , 5535 products { 5536 { 5537 type peptide , 5538 heading "Product" , 5539 accession "NP_000653" , 5540 version 3 , 5541 source { 5542 { 5543 src { 5544 db "Protein" , 5545 tag 5546 id 42741671 } , 5547 anchor "NP_000653" , 5548 post-text "N-acetyltransferase 1" } } , 5549 seqs { 5550 whole 5551 gi 42741671 } , 5552 comment { 5553 { 5554 type other , 5555 heading "Consensus CDS (CCDS)" , 5556 version 0 , 5557 source { 5558 { 5559 src { 5560 db "CCDS" , 5561 tag 5562 str "CCDS6007.1" } , 5563 anchor "CCDS6007.1" } } } , 5564 { 5565 type other , 5566 heading "Conserved Domains" , 5567 version 0 , 5568 source { 5569 { 5570 src { 5571 db "PROT_CDD" , 5572 tag 5573 id 42741671 } , 5574 pre-text "(1)" , 5575 anchor "summary" } } , 5576 comment { 5577 { 5578 type other , 5579 version 0 , 5580 source { 5581 { 5582 src { 5583 db "CDD" , 5584 tag 5585 id 1353 } , 5586 anchor "pfam00797: Acetyltransf_2; 5587 N-acetyltransferase" } } , 5588 comment { 5589 { 5590 type other , 5591 text "Location: 20 - 280 Blast Score: 1195" , 5592 version 0 } } } } } } } } , 5593 comment { 5594 { 5595 type other , 5596 heading "Source Sequence" , 5597 version 0 , 5598 source { 5599 { 5600 src { 5601 db "Nucleotide" , 5602 tag 5603 str "AV754344,BC047666,BQ024509" } , 5604 anchor "AV754344,BC047666,BQ024509" } } , 5605 comment { 5606 { 5607 type other , 5608 version 0 } } } } } } } , 5609 { 5610 type comment , 5611 heading "Related Sequences" , 5612 version 0 , 5613 products { 5614 { 5615 type genomic , 5616 heading "Genomic" , 5617 accession "AF008204" , 5618 version 1 , 5619 source { 5620 { 5621 src { 5622 db "Nucleotide" , 5623 tag 5624 id 2618821 } , 5625 anchor "AF008204" } } , 5626 seqs { 5627 whole 5628 gi 2618821 } , 5629 products { 5630 { 5631 type peptide , 5632 accession "AAB84384" , 5633 version 1 , 5634 source { 5635 { 5636 src { 5637 db "Protein" , 5638 tag 5639 id 2258431 } , 5640 anchor "AAB84384" } } , 5641 seqs { 5642 whole 5643 gi 2258431 } } } } , 5644 { 5645 type genomic , 5646 heading "Genomic" , 5647 accession "AF032677" , 5648 version 1 , 5649 source { 5650 { 5651 src { 5652 db "Nucleotide" , 5653 tag 5654 id 2641552 } , 5655 anchor "AF032677" } } , 5656 seqs { 5657 whole 5658 gi 2641552 } , 5659 products { 5660 { 5661 type peptide , 5662 accession "AAB86878" , 5663 version 1 , 5664 source { 5665 { 5666 src { 5667 db "Protein" , 5668 tag 5669 id 2641553 } , 5670 anchor "AAB86878" } } , 5671 seqs { 5672 whole 5673 gi 2641553 } } } } , 5674 { 5675 type genomic , 5676 heading "Genomic" , 5677 accession "AF032678" , 5678 version 1 , 5679 source { 5680 { 5681 src { 5682 db "Nucleotide" , 5683 tag 5684 id 2641554 } , 5685 anchor "AF032678" } } , 5686 seqs { 5687 whole 5688 gi 2641554 } , 5689 products { 5690 { 5691 type peptide , 5692 accession "AAB86879" , 5693 version 1 , 5694 source { 5695 { 5696 src { 5697 db "Protein" , 5698 tag 5699 id 2641555 } , 5700 anchor "AAB86879" } } , 5701 seqs { 5702 whole 5703 gi 2641555 } } } } , 5704 { 5705 type genomic , 5706 heading "Genomic" , 5707 accession "AF067408" , 5708 version 1 , 5709 source { 5710 { 5711 src { 5712 db "Nucleotide" , 5713 tag 5714 id 3265061 } , 5715 anchor "AF067408" } } , 5716 seqs { 5717 whole 5718 gi 3265061 } , 5719 products { 5720 { 5721 type peptide , 5722 accession "AAC24707" , 5723 version 1 , 5724 source { 5725 { 5726 src { 5727 db "Protein" , 5728 tag 5729 id 3265062 } , 5730 anchor "AAC24707" } } , 5731 seqs { 5732 whole 5733 gi 3265062 } } } } , 5734 { 5735 type genomic , 5736 heading "Genomic" , 5737 accession "AF071552" , 5738 version 1 , 5739 source { 5740 { 5741 src { 5742 db "Nucleotide" , 5743 tag 5744 id 3265151 } , 5745 anchor "AF071552" } } , 5746 seqs { 5747 whole 5748 gi 3265151 } , 5749 products { 5750 { 5751 type peptide , 5752 accession "AAC24712" , 5753 version 1 , 5754 source { 5755 { 5756 src { 5757 db "Protein" , 5758 tag 5759 id 3265152 } , 5760 anchor "AAC24712" } } , 5761 seqs { 5762 whole 5763 gi 3265152 } } } } , 5764 { 5765 type genomic , 5766 heading "Genomic" , 5767 accession "AF082903" , 5768 version 1 , 5769 source { 5770 { 5771 src { 5772 db "Nucleotide" , 5773 tag 5774 id 3435297 } , 5775 anchor "AF082903" } } , 5776 seqs { 5777 whole 5778 gi 3435297 } , 5779 products { 5780 { 5781 type peptide , 5782 accession "AAD13343" , 5783 version 1 , 5784 source { 5785 { 5786 src { 5787 db "Protein" , 5788 tag 5789 id 3435298 } , 5790 anchor "AAD13343" } } , 5791 seqs { 5792 whole 5793 gi 3435298 } } } } , 5794 { 5795 type genomic , 5796 heading "Genomic" , 5797 accession "AF082904" , 5798 version 1 , 5799 source { 5800 { 5801 src { 5802 db "Nucleotide" , 5803 tag 5804 id 3435299 } , 5805 anchor "AF082904" } } , 5806 seqs { 5807 whole 5808 gi 3435299 } , 5809 products { 5810 { 5811 type peptide , 5812 accession "AAC32388" , 5813 version 1 , 5814 source { 5815 { 5816 src { 5817 db "Protein" , 5818 tag 5819 id 3435300 } , 5820 anchor "AAC32388" } } , 5821 seqs { 5822 whole 5823 gi 3435300 } } } } , 5824 { 5825 type genomic , 5826 heading "Genomic" , 5827 accession "AF308866" , 5828 version 1 , 5829 source { 5830 { 5831 src { 5832 db "Nucleotide" , 5833 tag 5834 id 10834832 } , 5835 anchor "AF308866" } } , 5836 seqs { 5837 whole 5838 gi 10834832 } , 5839 products { 5840 { 5841 type peptide , 5842 accession "AAG23842" , 5843 version 1 , 5844 source { 5845 { 5846 src { 5847 db "Protein" , 5848 tag 5849 id 10834833 } , 5850 anchor "AAG23842" } } , 5851 seqs { 5852 whole 5853 gi 10834833 } } } } , 5854 { 5855 type genomic , 5856 heading "Genomic" , 5857 accession "AJ278017" , 5858 version 1 , 5859 source { 5860 { 5861 src { 5862 db "Nucleotide" , 5863 tag 5864 id 9663144 } , 5865 anchor "AJ278017" } } , 5866 seqs { 5867 whole 5868 gi 9663144 } , 5869 products { 5870 { 5871 type peptide , 5872 accession "CAC01128" , 5873 version 1 , 5874 source { 5875 { 5876 src { 5877 db "Protein" , 5878 tag 5879 id 9663145 } , 5880 anchor "CAC01128" } } , 5881 seqs { 5882 whole 5883 gi 9663145 } } } } , 5884 { 5885 type genomic , 5886 heading "Genomic" , 5887 accession "AJ307007" , 5888 version 1 , 5889 source { 5890 { 5891 src { 5892 db "Nucleotide" , 5893 tag 5894 id 14018355 } , 5895 anchor "AJ307007" } } , 5896 seqs { 5897 whole 5898 gi 14018355 } , 5899 products { 5900 { 5901 type peptide , 5902 accession "CAC38345" , 5903 version 1 , 5904 source { 5905 { 5906 src { 5907 db "Protein" , 5908 tag 5909 id 14018356 } , 5910 anchor "CAC38345" } } , 5911 seqs { 5912 whole 5913 gi 14018356 } } } } , 5914 { 5915 type genomic , 5916 heading "Genomic" , 5917 accession "AY338489" , 5918 version 1 , 5919 source { 5920 { 5921 src { 5922 db "Nucleotide" , 5923 tag 5924 id 32815075 } , 5925 anchor "AY338489" } } , 5926 seqs { 5927 whole 5928 gi 32815075 } , 5929 products { 5930 { 5931 type peptide , 5932 accession "AAP88036" , 5933 version 1 , 5934 source { 5935 { 5936 src { 5937 db "Protein" , 5938 tag 5939 id 32815076 } , 5940 anchor "AAP88036" } } , 5941 seqs { 5942 whole 5943 gi 32815076 } } } } , 5944 { 5945 type genomic , 5946 heading "Genomic" , 5947 accession "AY376850" , 5948 version 1 , 5949 source { 5950 { 5951 src { 5952 db "Nucleotide" , 5953 tag 5954 id 34555772 } , 5955 anchor "AY376850" } } , 5956 seqs { 5957 whole 5958 gi 34555772 } , 5959 products { 5960 { 5961 type peptide , 5962 accession "AAQ74989" , 5963 version 1 , 5964 source { 5965 { 5966 src { 5967 db "Protein" , 5968 tag 5969 id 34555773 } , 5970 anchor "AAQ74989" } } , 5971 seqs { 5972 whole 5973 gi 34555773 } } } } , 5974 { 5975 type genomic , 5976 heading "Genomic" , 5977 accession "U80835" , 5978 version 1 , 5979 source { 5980 { 5981 src { 5982 db "Nucleotide" , 5983 tag 5984 id 2245375 } , 5985 anchor "U80835" } } , 5986 seqs { 5987 whole 5988 gi 2245375 } , 5989 products { 5990 { 5991 type peptide , 5992 accession "AAB62398" , 5993 version 1 , 5994 source { 5995 { 5996 src { 5997 db "Protein" , 5998 tag 5999 id 2245376 } , 6000 anchor "AAB62398" } } , 6001 seqs { 6002 whole 6003 gi 2245376 } } } } , 6004 { 6005 type genomic , 6006 heading "Genomic" , 6007 accession "X17059" , 6008 version 1 , 6009 source { 6010 { 6011 src { 6012 db "Nucleotide" , 6013 tag 6014 id 34993 } , 6015 anchor "X17059" } } , 6016 seqs { 6017 whole 6018 gi 34993 } , 6019 products { 6020 { 6021 type peptide , 6022 accession "CAA34905" , 6023 version 1 , 6024 source { 6025 { 6026 src { 6027 db "Protein" , 6028 tag 6029 id 34994 } , 6030 anchor "CAA34905" } } , 6031 seqs { 6032 whole 6033 gi 34994 } } } } , 6034 { 6035 type mRNA , 6036 heading "mRNA" , 6037 accession "AV754344" , 6038 version 1 , 6039 source { 6040 { 6041 src { 6042 db "Nucleotide" , 6043 tag 6044 id 10912192 } , 6045 anchor "AV754344" } } , 6046 seqs { 6047 whole 6048 gi 10912192 } , 6049 products { 6050 { 6051 type peptide , 6052 text "None" , 6053 version 0 } } } , 6054 { 6055 type mRNA , 6056 heading "mRNA" , 6057 accession "BC013732" , 6058 version 1 , 6059 source { 6060 { 6061 src { 6062 db "Nucleotide" , 6063 tag 6064 id 16975545 } , 6065 anchor "BC013732" } } , 6066 seqs { 6067 whole 6068 gi 16975545 } , 6069 products { 6070 { 6071 type peptide , 6072 text "None" , 6073 version 0 } } } , 6074 { 6075 type mRNA , 6076 heading "mRNA" , 6077 accession "BC047666" , 6078 version 1 , 6079 source { 6080 { 6081 src { 6082 db "Nucleotide" , 6083 tag 6084 id 28838335 } , 6085 anchor "BC047666" } } , 6086 seqs { 6087 whole 6088 gi 28838335 } , 6089 products { 6090 { 6091 type peptide , 6092 accession "AAH47666" , 6093 version 1 , 6094 source { 6095 { 6096 src { 6097 db "Protein" , 6098 tag 6099 id 28838336 } , 6100 anchor "AAH47666" } } , 6101 seqs { 6102 whole 6103 gi 28838336 } } } } , 6104 { 6105 type mRNA , 6106 heading "mRNA" , 6107 accession "BQ024509" , 6108 version 1 , 6109 source { 6110 { 6111 src { 6112 db "Nucleotide" , 6113 tag 6114 id 19759788 } , 6115 anchor "BQ024509" } } , 6116 seqs { 6117 whole 6118 gi 19759788 } , 6119 products { 6120 { 6121 type peptide , 6122 text "None" , 6123 version 0 } } } , 6124 { 6125 type mRNA , 6126 heading "mRNA" , 6127 accession "BX647521" , 6128 version 1 , 6129 source { 6130 { 6131 src { 6132 db "Nucleotide" , 6133 tag 6134 id 34366678 } , 6135 anchor "BX647521" } } , 6136 seqs { 6137 whole 6138 gi 34366678 } , 6139 products { 6140 { 6141 type peptide , 6142 text "None" , 6143 version 0 } } } , 6144 { 6145 type mRNA , 6146 heading "mRNA" , 6147 accession "D90041" , 6148 version 1 , 6149 source { 6150 { 6151 src { 6152 db "Nucleotide" , 6153 tag 6154 id 219413 } , 6155 anchor "D90041" } } , 6156 seqs { 6157 whole 6158 gi 219413 } , 6159 products { 6160 { 6161 type peptide , 6162 accession "BAA14095" , 6163 version 1 , 6164 source { 6165 { 6166 src { 6167 db "Protein" , 6168 tag 6169 id 219414 } , 6170 anchor "BAA14095" } } , 6171 seqs { 6172 whole 6173 gi 219414 } } } } , 6174 { 6175 type other , 6176 text "None" , 6177 version 0 , 6178 products { 6179 { 6180 type peptide , 6181 accession "P18440" , 6182 version 0 , 6183 source { 6184 { 6185 src { 6186 db "Protein" , 6187 tag 6188 id 114234 } , 6189 anchor "P18440" } } , 6190 seqs { 6191 whole 6192 gi 114234 } } } } } } , 6193 { 6194 type comment , 6195 heading "Additional Links" , 6196 version 0 , 6197 comment { 6198 { 6199 type comment , 6200 version 0 , 6201 source { 6202 { 6203 src { 6204 db "Evidence Viewer" , 6205 tag 6206 str "9" } , 6207 anchor "Evidence Viewer" , 6208 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 6209g=NT_030737.9&gene=NAT1&lid=9&from=5912543&to=5925748" } } } , 6210 { 6211 type comment , 6212 version 0 , 6213 source { 6214 { 6215 src { 6216 db "ModelMaker" , 6217 tag 6218 str "9" } , 6219 anchor "ModelMaker" , 6220 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 622106&contig=NT_030737.9&gene=NAT1&lid=9" } } } , 6222 { 6223 type comment , 6224 text "UniGene" , 6225 version 0 , 6226 xtra-properties { 6227 { 6228 tag "UNIGENE" , 6229 value "Hs.155956" } } , 6230 source { 6231 { 6232 src { 6233 db "UniGene" , 6234 tag 6235 str "Hs.155956" } , 6236 anchor "Hs.155956" , 6237 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=15 62385956" } } } , 6239 { 6240 type comment , 6241 text "MIM" , 6242 version 0 , 6243 source { 6244 { 6245 src { 6246 db "MIM" , 6247 tag 6248 str "108345" } , 6249 anchor "108345" } } } , 6250 { 6251 type comment , 6252 version 0 , 6253 source { 6254 { 6255 src { 6256 db "HomoloGene" , 6257 tag 6258 str "9" } , 6259 anchor "HomoloGene" , 6260 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 62619[loc]&TAXID=9606" } } } , 6262 { 6263 type comment , 6264 version 0 , 6265 source { 6266 { 6267 src { 6268 db "AceView" , 6269 tag 6270 id 9 } , 6271 anchor "AceView" , 6272 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 6273ocusid&org=9606&l=9" } } } , 6274 { 6275 type comment , 6276 version 0 , 6277 source { 6278 { 6279 src { 6280 db "GDB" , 6281 tag 6282 str "GDB:125364" } } } } , 6283 { 6284 type comment , 6285 version 0 , 6286 source { 6287 { 6288 src { 6289 db "Ensembl" , 6290 tag 6291 str "" } , 6292 url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=BC013 6293732" } } } , 6294 { 6295 type comment , 6296 version 0 , 6297 source { 6298 { 6299 src { 6300 db "UCSC" , 6301 tag 6302 str "" } , 6303 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position= 6304BC013732" } } } , 6305 { 6306 type comment , 6307 text "PharmGKB" , 6308 version 0 , 6309 source { 6310 { 6311 src { 6312 db "PharmGKB" , 6313 tag 6314 str "PA17" } , 6315 anchor "PA17" } } } , 6316 { 6317 type comment , 6318 text "Arylamine N-Acetyltransferase Nomenclature" , 6319 version 0 , 6320 source { 6321 { 6322 src { 6323 db "Arylamine N-Acetyltransferase Nomenclature" , 6324 tag 6325 str "Arylamine N-Acetyltransferase Nomenclature" } , 6326 anchor "Arylamine N-Acetyltransferase Nomenclature" , 6327 url "http://www.louisville.edu/medschool/pharmacology/NAT.html" } } } , 6328 { 6329 type comment , 6330 version 0 , 6331 source { 6332 { 6333 src { 6334 db "MGC" , 6335 tag 6336 str "BC047666" } , 6337 anchor "MGC" , 6338 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC047666" } } } } } , 6339 { 6340 type generif , 6341 text "In breast, NAT1 mRNA is transcribed from a strong promoter located 6342 11.8 kb upstream of the translated exon, and the mature spliced mRNA includes 6343 at least one additional non-coding exon." , 6344 version 0 , 6345 refs { 6346 pmid 15226672 } , 6347 create-date 6348 str "Mar 26 2005 10:01AM" , 6349 update-date 6350 str "Mar 26 2005 1:53PM" } , 6351 { 6352 type generif , 6353 text "Polymorphism at the NAT1 locus has been associated with the 6354 existence of at least 26 allelic variants, generating phenotypic variations 6355 in terms NAT-1 catalytic activity. This genetic variation affects the 6356 acetylator status of individuals." , 6357 version 0 , 6358 refs { 6359 pmid 15320760 } , 6360 create-date 6361 str "Dec 18 2004 10:01AM" , 6362 update-date 6363 str "Mar 17 2005 6:52AM" } , 6364 { 6365 type generif , 6366 text "NAT1 exists in the cell in either a stable acetylated state or an 6367 unstable non-acetylated state and mutations in the NAT1 gene that prevent 6368 protein acetylation produce a slow acetylator phenotype" , 6369 version 0 , 6370 refs { 6371 pmid 15039438 } , 6372 create-date 6373 str "Jul 6 2004 11:50AM" , 6374 update-date 6375 str "Jul 6 2004 12:11PM" } , 6376 { 6377 type generif , 6378 text "Analysis of the effect of active NAT-1 overexpression in a normal 6379 luminal epithelial-derived cell line demonstrated enhanced growth properties 6380 and etoposide resistance relative to control cells." , 6381 version 0 , 6382 refs { 6383 pmid 14517345 } , 6384 create-date 6385 str "Jun 23 2004 4:43PM" , 6386 update-date 6387 str "Jun 23 2004 5:16PM" } , 6388 { 6389 type generif , 6390 text "cellular generation of peroxynitrite may contribute to 6391 carcinogenesis and tumor progression by weakening key cellular defense 6392 enzymes such as arylamine N-acetyltransferase 1 (NAT1)" , 6393 version 0 , 6394 refs { 6395 pmid 14672957 } , 6396 create-date 6397 str "Mar 24 2004 12:00AM" , 6398 update-date 6399 str "May 9 2004 7:01AM" } , 6400 { 6401 type generif , 6402 text "although there is little overall association between NAT genotypes 6403 and risk of developing systemic lupus erythematosus, the interaction between 6404 NAT1 and NAT2 and specific exposures such as hair dyes may be important." , 6405 version 0 , 6406 refs { 6407 pmid 14705222 } , 6408 create-date 6409 str "Apr 16 2004 12:00AM" , 6410 update-date 6411 str "May 2 2004 7:01AM" } , 6412 { 6413 type generif , 6414 text "A putative RUNX1 binding site variant of NAT9 is associated with 6415 susceptibility to psoriasis" , 6416 version 0 , 6417 refs { 6418 pmid 14608357 } , 6419 create-date 6420 str "Dec 18 2003 12:00AM" , 6421 update-date 6422 str "Jan 11 2004 7:03AM" } , 6423 { 6424 type generif , 6425 text "Identification of minimal promoter sequences for transcription 6426 factor binding sites in the human N-acetyltransferase Type I gene. that binds" , 6427 version 0 , 6428 refs { 6429 pmid 12946272 } , 6430 create-date 6431 str "Nov 24 2003 12:00AM" , 6432 update-date 6433 str "Dec 7 2003 7:02AM" } , 6434 { 6435 type generif , 6436 text "Oxidative stress and cellular redox status may regulate NAT1 6437 activity and have important consequences with regard to drug 6438 biotransformation and cancer risk." , 6439 version 0 , 6440 refs { 6441 pmid 12832400 } , 6442 create-date 6443 str "Oct 7 2003 12:00AM" , 6444 update-date 6445 str "Nov 16 2003 7:02AM" } , 6446 { 6447 type generif , 6448 text "Variation in capacity for acetylation of 4ABP and PABA resulting 6449 from human NAT1 transgene is insufficient to affect 4ABP genotoxicity in 6450 mouse liver." , 6451 version 0 , 6452 refs { 6453 pmid 12902152 } , 6454 create-date 6455 str "Sep 6 2003 12:00AM" , 6456 update-date 6457 str "Sep 14 2003 7:01AM" } , 6458 { 6459 type generif , 6460 text "It is unlikely that the NAT1*10 or NAT2 rapid/intermediate 6461 genotypes are related to stomach cancer risk." , 6462 version 0 , 6463 refs { 6464 pmid 12692115 } , 6465 create-date 6466 str "Sep 4 2003 12:00AM" , 6467 update-date 6468 str "Sep 28 2003 7:01AM" } , 6469 { 6470 type generif , 6471 text "genetic polymorphisms of NAT1 and NAT2 have no independent effect 6472 on breast cancer risk, but they modulate breast cancer risk in the presence 6473 of GSTM1 and GSTT1 null genotypes." , 6474 version 0 , 6475 refs { 6476 pmid 12860276 } , 6477 create-date 6478 str "Aug 18 2003 12:00AM" , 6479 update-date 6480 str "Aug 24 2003 7:01AM" } , 6481 { 6482 type generif , 6483 text "NAT1 * 10 has increased risk of sporadic colorectal adenocarcinoma 6484 and significantly related to the later stage tumors, is not significantly 6485 related to the tumor location" , 6486 version 0 , 6487 refs { 6488 pmid 12485520 } , 6489 create-date 6490 str "Jun 25 2003 12:00AM" , 6491 update-date 6492 str "Jul 13 2003 7:01AM" } , 6493 { 6494 type generif , 6495 text "Single nucleotide polymorphisms of NAT1 and NAT2, and acetylation 6496 haplotype were not associated with increased risk for Parkinson disease" , 6497 version 0 , 6498 refs { 6499 pmid 12682333 } , 6500 create-date 6501 str "Apr 11 2003 12:00AM" , 6502 update-date 6503 str "Apr 27 2003 7:01AM" } , 6504 { 6505 type generif , 6506 text "NAT1 polymorphism (NAT1*10) indicates increased susceptibility to 6507 prostate cancer" , 6508 version 0 , 6509 refs { 6510 pmid 12355549 } , 6511 create-date 6512 str "Oct 31 2002 12:00AM" , 6513 update-date 6514 str "Feb 2 2003 7:01AM" } , 6515 { 6516 type generif , 6517 text "susceptibility gene for multifactorial adverse effects and 6518 xenobiotic-related diseases (review)" , 6519 version 0 , 6520 refs { 6521 pmid 12052143 } , 6522 create-date 6523 str "Sep 12 2002 12:00AM" , 6524 update-date 6525 str "Sep 16 2002 5:48AM" } , 6526 { 6527 type generif , 6528 text "NAT1 genotype acts as a modifier of diisothionate 6529 exposure-associated asthma risk" , 6530 version 0 , 6531 refs { 6532 pmid 11927838 } , 6533 create-date 6534 str "Aug 30 2002 12:00AM" , 6535 update-date 6536 str "Sep 16 2002 5:48AM" } , 6537 { 6538 type generif , 6539 text "NAT1 polymorphisms may be correlated with an increased risk of 6540 larynx cancer" , 6541 version 0 , 6542 refs { 6543 pmid 12037388 } , 6544 create-date 6545 str "Aug 19 2002 12:00AM" , 6546 update-date 6547 str "Aug 28 2002 6:15PM" } , 6548 { 6549 type generif , 6550 text "paclitaxel affected human leukemia HL-60 cells arylamine 6551 N-acetyltransferase (NAT) activity and DNA-2-aminofluorene adduct formation." , 6552 version 0 , 6553 refs { 6554 pmid 11955677 } , 6555 create-date 6556 str "Jun 19 2002 12:00AM" , 6557 update-date 6558 str "Jun 24 2002 6:31AM" } , 6559 { 6560 type generif , 6561 text "paclitaxel is an uncompetitive inhibitor to arylamine 6562 N-acetyltransferase (NAT) enzyme" , 6563 version 0 , 6564 refs { 6565 pmid 11955676 } , 6566 create-date 6567 str "Jun 19 2002 12:00AM" , 6568 update-date 6569 str "Jun 24 2002 6:31AM" } } , 6570 unique-keys { 6571 { 6572 db "LocusID" , 6573 tag 6574 id 9 } , 6575 { 6576 db "MIM" , 6577 tag 6578 id 108345 } } , 6579 xtra-index-terms { 6580 "LOC9" } } 6581Entrezgene ::= { 6582 track-info { 6583 geneid 10 , 6584 status live , 6585 create-date 6586 std { 6587 year 2003 , 6588 month 8 , 6589 day 28 , 6590 hour 20 , 6591 minute 30 , 6592 second 0 } , 6593 update-date 6594 std { 6595 year 2005 , 6596 month 4 , 6597 day 17 , 6598 hour 11 , 6599 minute 9 , 6600 second 0 } } , 6601 type protein-coding , 6602 source { 6603 genome genomic , 6604 origin natural , 6605 org { 6606 taxname "Homo sapiens" , 6607 common "human" , 6608 db { 6609 { 6610 db "taxon" , 6611 tag 6612 id 9606 } } , 6613 syn { 6614 "man" } , 6615 orgname { 6616 name 6617 binomial { 6618 genus "Homo" , 6619 species "sapiens" } , 6620 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 6621 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 6622 Hominidae; Homo" , 6623 gcode 1 , 6624 mgcode 2 , 6625 div "PRI" } } , 6626 subtype { 6627 { 6628 subtype chromosome , 6629 name "8" } } } , 6630 gene { 6631 locus "NAT2" , 6632 desc "N-acetyltransferase 2 (arylamine N-acetyltransferase)" , 6633 maploc "8p22" , 6634 db { 6635 { 6636 db "MIM" , 6637 tag 6638 id 243400 } } , 6639 syn { 6640 "AAC2" } , 6641 locus-tag "HGNC:7646" } , 6642 prot { 6643 name { 6644 "arylamide acetylase 2" , 6645 "Arylamine N-acetyltransferase-2" , 6646 "arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation)" } } , 6647 summary "The intronless NAT2 gene encodes N-acetyltransferase 2 (arylamine 6648 N-acetyltransferase 2). This enzyme functions to both activate and deactivate 6649 arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are 6650 reponsible for the N-acetylation polymorphism in which human populations 6651 segregate into rapid,intermediate, and slow acetylator phenotypes. 6652 Polymorphisms in NAT2 are also associated with higher incidences of cancer 6653 and drug toxicity.A second arylamine N-acetyltransferase gene (NAT1) is 6654 located near NAT2." , 6655 location { 6656 { 6657 display-str "8p22" , 6658 method 6659 map-type cyto } } , 6660 gene-source { 6661 src "LocusLink" , 6662 src-int 10 , 6663 src-str2 "10" , 6664 gene-display FALSE , 6665 locus-display FALSE , 6666 extra-terms FALSE } , 6667 locus { 6668 { 6669 type genomic , 6670 heading "Reference" , 6671 accession "NC_000008" , 6672 version 9 , 6673 seqs { 6674 int { 6675 from 18293034 , 6676 to 18302961 , 6677 strand plus , 6678 id 6679 gi 51511724 } } , 6680 products { 6681 { 6682 type mRNA , 6683 heading "Reference" , 6684 accession "NM_000015" , 6685 version 1 , 6686 genomic-coords { 6687 mix { 6688 int { 6689 from 18293034 , 6690 to 18293134 , 6691 strand plus , 6692 id 6693 gi 51511724 } , 6694 int { 6695 from 18301787 , 6696 to 18302961 , 6697 strand plus , 6698 id 6699 gi 51511724 } } } , 6700 seqs { 6701 whole 6702 gi 4557782 } , 6703 products { 6704 { 6705 type peptide , 6706 heading "Reference" , 6707 accession "NP_000006" , 6708 version 1 , 6709 genomic-coords { 6710 int { 6711 from 18301793 , 6712 to 18302665 , 6713 strand plus , 6714 id 6715 gi 51511724 } } , 6716 seqs { 6717 whole 6718 gi 4557783 } , 6719 comment { 6720 { 6721 type property , 6722 label "EC" , 6723 text "2.3.1.5" , 6724 version 0 , 6725 xtra-properties { 6726 { 6727 tag "EC" , 6728 value "2.3.1.5" } } } } } } } } } , 6729 { 6730 type genomic , 6731 heading "Reference" , 6732 accession "NT_030737" , 6733 version 9 , 6734 seqs { 6735 int { 6736 from 6093682 , 6737 to 6103609 , 6738 strand plus , 6739 id 6740 gi 51466871 } } , 6741 products { 6742 { 6743 type mRNA , 6744 heading "Reference" , 6745 accession "NM_000015" , 6746 version 1 , 6747 genomic-coords { 6748 mix { 6749 int { 6750 from 6093682 , 6751 to 6093782 , 6752 strand plus , 6753 id 6754 gi 51466871 } , 6755 int { 6756 from 6102435 , 6757 to 6103609 , 6758 strand plus , 6759 id 6760 gi 51466871 } } } , 6761 seqs { 6762 whole 6763 gi 4557782 } , 6764 products { 6765 { 6766 type peptide , 6767 heading "Reference" , 6768 accession "NP_000006" , 6769 version 1 , 6770 genomic-coords { 6771 int { 6772 from 6102441 , 6773 to 6103313 , 6774 strand plus , 6775 id 6776 gi 51466871 } } , 6777 seqs { 6778 whole 6779 gi 4557783 } , 6780 comment { 6781 { 6782 type property , 6783 label "EC" , 6784 text "2.3.1.5" , 6785 version 0 , 6786 xtra-properties { 6787 { 6788 tag "EC" , 6789 value "2.3.1.5" } } } } } } } } } , 6790 { 6791 type genomic , 6792 heading "Reference" , 6793 accession "NT_086740" , 6794 version 1 , 6795 seqs { 6796 int { 6797 from 5773920 , 6798 to 5783845 , 6799 strand plus , 6800 id 6801 gi 51467159 } } , 6802 products { 6803 { 6804 type mRNA , 6805 heading "Reference" , 6806 accession "NM_000015" , 6807 version 1 , 6808 genomic-coords { 6809 mix { 6810 int { 6811 from 5773920 , 6812 to 5774020 , 6813 strand plus , 6814 id 6815 gi 51467159 } , 6816 int { 6817 from 5782671 , 6818 to 5783845 , 6819 strand plus , 6820 id 6821 gi 51467159 } } } , 6822 seqs { 6823 whole 6824 gi 4557782 } , 6825 products { 6826 { 6827 type peptide , 6828 heading "Reference" , 6829 accession "NP_000006" , 6830 version 1 , 6831 genomic-coords { 6832 int { 6833 from 5782677 , 6834 to 5783549 , 6835 strand plus , 6836 id 6837 gi 51467159 } } , 6838 seqs { 6839 whole 6840 gi 4557783 } , 6841 comment { 6842 { 6843 type property , 6844 label "EC" , 6845 text "2.3.1.5" , 6846 version 0 , 6847 xtra-properties { 6848 { 6849 tag "EC" , 6850 value "2.3.1.5" } } } } } } } } } } , 6851 properties { 6852 { 6853 type comment , 6854 label "Nomenclature" , 6855 version 0 , 6856 source { 6857 { 6858 anchor "HUGO Gene Nomenclature Committee" } } , 6859 properties { 6860 { 6861 type property , 6862 label "Official Symbol" , 6863 text "NAT2" , 6864 version 0 } , 6865 { 6866 type property , 6867 label "Official Full Name" , 6868 text "N-acetyltransferase 2 (arylamine N-acetyltransferase)" , 6869 version 0 } } } , 6870 { 6871 type comment , 6872 heading "GeneOntology" , 6873 version 0 , 6874 source { 6875 { 6876 pre-text "Provided by" , 6877 anchor "GOA" , 6878 url "http://www.ebi.ac.uk/GOA/" } } , 6879 comment { 6880 { 6881 type comment , 6882 label "Function" , 6883 version 0 , 6884 comment { 6885 { 6886 type comment , 6887 version 0 , 6888 source { 6889 { 6890 src { 6891 db "GO" , 6892 tag 6893 id 16407 } , 6894 anchor "acetyltransferase activity" , 6895 post-text "evidence: IEA" } } } , 6896 { 6897 type comment , 6898 version 0 , 6899 refs { 6900 pmid 2340091 } , 6901 source { 6902 { 6903 src { 6904 db "GO" , 6905 tag 6906 id 4060 } , 6907 anchor "arylamine N-acetyltransferase activity" , 6908 post-text "evidence: TAS" } } } , 6909 { 6910 type comment , 6911 version 0 , 6912 source { 6913 { 6914 src { 6915 db "GO" , 6916 tag 6917 id 16740 } , 6918 anchor "transferase activity" , 6919 post-text "evidence: IEA" } } } } } , 6920 { 6921 type comment , 6922 label "Process" , 6923 version 0 , 6924 comment { 6925 { 6926 type comment , 6927 version 0 , 6928 source { 6929 { 6930 src { 6931 db "GO" , 6932 tag 6933 id 8152 } , 6934 anchor "metabolism" , 6935 post-text "evidence: IEA" } } } } } } } } , 6936 homology { 6937 { 6938 type comment , 6939 heading "Mouse, Rat" , 6940 version 0 , 6941 source { 6942 { 6943 src { 6944 db "HomoloGene" , 6945 tag 6946 id 32047 } , 6947 anchor "Map Viewer" , 6948 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=8&M 6949APS=genes-r-org/rat-chr/human%3A8,genes-r-org/mouse-chr/human%3A8,genes-r-org/ 6950human-chr8&query=e%3A10[id]+AND+gene[obj_type]&QSTR=nat2&cmd=focus&fill=10" } } } } , 6951 comments { 6952 { 6953 type comment , 6954 heading "LocusTagLink" , 6955 version 0 , 6956 source { 6957 { 6958 src { 6959 db "HGNC" , 6960 tag 6961 id 7646 } } } } , 6962 { 6963 type comment , 6964 heading "RefSeq Status" , 6965 label "REVIEWED" , 6966 version 0 } , 6967 { 6968 type comment , 6969 version 0 , 6970 refs { 6971 pmid 15671210 , 6972 pmid 15637738 , 6973 pmid 15609332 , 6974 pmid 15588473 , 6975 pmid 15225898 , 6976 pmid 15162844 , 6977 pmid 15005011 , 6978 pmid 14747882 , 6979 pmid 14705222 , 6980 pmid 14648207 , 6981 pmid 14618622 , 6982 pmid 14528063 , 6983 pmid 12884528 , 6984 pmid 12877350 , 6985 pmid 12860276 , 6986 pmid 12835615 , 6987 pmid 12773763 , 6988 pmid 12760253 , 6989 pmid 12724621 , 6990 pmid 12692115 , 6991 pmid 12682333 , 6992 pmid 12654968 , 6993 pmid 12622714 , 6994 pmid 12611196 , 6995 pmid 12477932 , 6996 pmid 12474054 , 6997 pmid 12469231 , 6998 pmid 12465141 , 6999 pmid 12430181 , 7000 pmid 12397635 , 7001 pmid 12360107 , 7002 pmid 12355549 , 7003 pmid 12235453 , 7004 pmid 12222688 , 7005 pmid 12163321 , 7006 pmid 12037388 , 7007 pmid 12016157 , 7008 pmid 12015038 , 7009 pmid 11915035 , 7010 pmid 11872636 , 7011 pmid 11846845 , 7012 pmid 11470991 , 7013 pmid 9202751 , 7014 pmid 8460648 , 7015 pmid 8110178 , 7016 pmid 8102597 , 7017 pmid 7915226 , 7018 pmid 7902079 , 7019 pmid 7773298 , 7020 pmid 2734109 , 7021 pmid 2340091 , 7022 pmid 2068113 , 7023 pmid 1996083 , 7024 pmid 1968463 , 7025 pmid 1676262 , 7026 pmid 1441598 , 7027 pmid 1381364 , 7028 pmid 1306121 } } , 7029 { 7030 type comment , 7031 heading "Markers (Sequence Tagged Sites/STS)" , 7032 version 0 , 7033 comment { 7034 { 7035 type comment , 7036 version 0 , 7037 source { 7038 { 7039 src { 7040 db "UniSTS" , 7041 tag 7042 id 17088 } , 7043 anchor "G06461" , 7044 post-text "(e-PCR)" } } , 7045 comment { 7046 { 7047 type other , 7048 label "Alternate name" , 7049 text "WI-7224" , 7050 version 0 } } } , 7051 { 7052 type comment , 7053 version 0 , 7054 source { 7055 { 7056 src { 7057 db "UniSTS" , 7058 tag 7059 id 44576 } , 7060 anchor "WIAF-2120" , 7061 post-text "(e-PCR)" } } , 7062 comment { 7063 { 7064 type other , 7065 label "Alternate name" , 7066 text "RH11442" , 7067 version 0 } , 7068 { 7069 type other , 7070 label "Alternate name" , 7071 text "RH20" , 7072 version 0 } , 7073 { 7074 type other , 7075 label "Alternate name" , 7076 text "WIAF-2120-STS" , 7077 version 0 } , 7078 { 7079 type other , 7080 label "Alternate name" , 7081 text "gdb:4559542" , 7082 version 0 } , 7083 { 7084 type other , 7085 label "Alternate name" , 7086 text "stSG40" , 7087 version 0 } } } , 7088 { 7089 type comment , 7090 version 0 , 7091 source { 7092 { 7093 src { 7094 db "UniSTS" , 7095 tag 7096 id 137181 } , 7097 anchor "G59899" , 7098 post-text "(e-PCR)" } } , 7099 comment { 7100 { 7101 type other , 7102 label "Alternate name" , 7103 text "SHGC-130680" , 7104 version 0 } } } , 7105 { 7106 type comment , 7107 version 0 , 7108 source { 7109 { 7110 src { 7111 db "UniSTS" , 7112 tag 7113 id 155563 } , 7114 anchor "GDB:187676" , 7115 post-text "(e-PCR)" } } } , 7116 { 7117 type comment , 7118 version 0 , 7119 source { 7120 { 7121 src { 7122 db "UniSTS" , 7123 tag 7124 id 156422 } , 7125 anchor "GDB:310612" , 7126 post-text "(e-PCR)" } } } , 7127 { 7128 type comment , 7129 version 0 , 7130 source { 7131 { 7132 src { 7133 db "UniSTS" , 7134 tag 7135 id 156423 } , 7136 anchor "GDB:310613" , 7137 post-text "(e-PCR)" } } } , 7138 { 7139 type comment , 7140 version 0 , 7141 source { 7142 { 7143 src { 7144 db "UniSTS" , 7145 tag 7146 id 157141 } , 7147 anchor "GDB:386004" , 7148 post-text "(e-PCR)" } } } , 7149 { 7150 type comment , 7151 version 0 , 7152 source { 7153 { 7154 src { 7155 db "UniSTS" , 7156 tag 7157 id 272646 } , 7158 anchor "PMC310725P3" , 7159 post-text "(e-PCR)" } } } } } , 7160 { 7161 type comment , 7162 heading "NCBI Reference Sequences (RefSeq)" , 7163 version 0 , 7164 products { 7165 { 7166 type mRNA , 7167 heading "mRNA Sequence" , 7168 accession "NM_000015" , 7169 version 1 , 7170 source { 7171 { 7172 src { 7173 db "Nucleotide" , 7174 tag 7175 id 4557782 } , 7176 anchor "NM_000015" } } , 7177 seqs { 7178 whole 7179 gi 4557782 } , 7180 products { 7181 { 7182 type peptide , 7183 heading "Product" , 7184 accession "NP_000006" , 7185 version 1 , 7186 source { 7187 { 7188 src { 7189 db "Protein" , 7190 tag 7191 id 4557783 } , 7192 anchor "NP_000006" , 7193 post-text "arylamide acetylase 2" } } , 7194 seqs { 7195 whole 7196 gi 4557783 } , 7197 comment { 7198 { 7199 type other , 7200 heading "Consensus CDS (CCDS)" , 7201 version 0 , 7202 source { 7203 { 7204 src { 7205 db "CCDS" , 7206 tag 7207 str "CCDS6008.1" } , 7208 anchor "CCDS6008.1" } } } , 7209 { 7210 type other , 7211 heading "Conserved Domains" , 7212 version 0 , 7213 source { 7214 { 7215 src { 7216 db "PROT_CDD" , 7217 tag 7218 id 4557783 } , 7219 pre-text "(1)" , 7220 anchor "summary" } } , 7221 comment { 7222 { 7223 type other , 7224 version 0 , 7225 source { 7226 { 7227 src { 7228 db "CDD" , 7229 tag 7230 id 1353 } , 7231 anchor "pfam00797: Acetyltransf_2; 7232 N-acetyltransferase" } } , 7233 comment { 7234 { 7235 type other , 7236 text "Location: 20 - 280 Blast Score: 1005" , 7237 version 0 } } } } } } } } , 7238 comment { 7239 { 7240 type other , 7241 heading "Source Sequence" , 7242 version 0 , 7243 source { 7244 { 7245 src { 7246 db "Nucleotide" , 7247 tag 7248 str "D90042" } , 7249 anchor "D90042" } } , 7250 comment { 7251 { 7252 type other , 7253 version 0 } } } } } } } , 7254 { 7255 type comment , 7256 heading "Related Sequences" , 7257 version 0 , 7258 products { 7259 { 7260 type genomic , 7261 heading "Genomic" , 7262 accession "AF042740" , 7263 version 1 , 7264 source { 7265 { 7266 src { 7267 db "Nucleotide" , 7268 tag 7269 id 2801806 } , 7270 anchor "AF042740" } } , 7271 seqs { 7272 whole 7273 gi 2801806 } , 7274 products { 7275 { 7276 type peptide , 7277 accession "AAC03773" , 7278 version 1 , 7279 source { 7280 { 7281 src { 7282 db "Protein" , 7283 tag 7284 id 2801807 } , 7285 anchor "AAC03773" } } , 7286 seqs { 7287 whole 7288 gi 2801807 } } } } , 7289 { 7290 type genomic , 7291 heading "Genomic" , 7292 accession "AF055874" , 7293 version 1 , 7294 source { 7295 { 7296 src { 7297 db "Nucleotide" , 7298 tag 7299 id 3063613 } , 7300 anchor "AF055874" } } , 7301 seqs { 7302 whole 7303 gi 3063613 } , 7304 products { 7305 { 7306 type peptide , 7307 accession "AAC14117" , 7308 version 1 , 7309 source { 7310 { 7311 src { 7312 db "Protein" , 7313 tag 7314 id 3063614 } , 7315 anchor "AAC14117" } } , 7316 seqs { 7317 whole 7318 gi 3063614 } } } } , 7319 { 7320 type genomic , 7321 heading "Genomic" , 7322 accession "AF055875" , 7323 version 1 , 7324 source { 7325 { 7326 src { 7327 db "Nucleotide" , 7328 tag 7329 id 3063615 } , 7330 anchor "AF055875" } } , 7331 seqs { 7332 whole 7333 gi 3063615 } , 7334 products { 7335 { 7336 type peptide , 7337 accession "AAC14118" , 7338 version 1 , 7339 source { 7340 { 7341 src { 7342 db "Protein" , 7343 tag 7344 id 3063616 } , 7345 anchor "AAC14118" } } , 7346 seqs { 7347 whole 7348 gi 3063616 } } } } , 7349 { 7350 type genomic , 7351 heading "Genomic" , 7352 accession "AF320309" , 7353 version 1 , 7354 source { 7355 { 7356 src { 7357 db "Nucleotide" , 7358 tag 7359 id 11321494 } , 7360 anchor "AF320309" } } , 7361 seqs { 7362 whole 7363 gi 11321494 } , 7364 products { 7365 { 7366 type peptide , 7367 accession "AAG34181" , 7368 version 1 , 7369 source { 7370 { 7371 src { 7372 db "Protein" , 7373 tag 7374 id 11321495 } , 7375 anchor "AAG34181" } } , 7376 seqs { 7377 whole 7378 gi 11321495 } } } } , 7379 { 7380 type genomic , 7381 heading "Genomic" , 7382 accession "AF348074" , 7383 version 1 , 7384 source { 7385 { 7386 src { 7387 db "Nucleotide" , 7388 tag 7389 id 14009675 } , 7390 anchor "AF348074" } } , 7391 seqs { 7392 whole 7393 gi 14009675 } , 7394 products { 7395 { 7396 type peptide , 7397 accession "AAK51710" , 7398 version 1 , 7399 source { 7400 { 7401 src { 7402 db "Protein" , 7403 tag 7404 id 14009676 } , 7405 anchor "AAK51710" } } , 7406 seqs { 7407 whole 7408 gi 14009676 } } } } , 7409 { 7410 type genomic , 7411 heading "Genomic" , 7412 accession "AF348075" , 7413 version 1 , 7414 source { 7415 { 7416 src { 7417 db "Nucleotide" , 7418 tag 7419 id 14009677 } , 7420 anchor "AF348075" } } , 7421 seqs { 7422 whole 7423 gi 14009677 } , 7424 products { 7425 { 7426 type peptide , 7427 accession "AAK51711" , 7428 version 1 , 7429 source { 7430 { 7431 src { 7432 db "Protein" , 7433 tag 7434 id 14009678 } , 7435 anchor "AAK51711" } } , 7436 seqs { 7437 whole 7438 gi 14009678 } } } } , 7439 { 7440 type genomic , 7441 heading "Genomic" , 7442 accession "AY230251" , 7443 version 1 , 7444 source { 7445 { 7446 src { 7447 db "Nucleotide" , 7448 tag 7449 id 29423785 } , 7450 anchor "AY230251" } } , 7451 seqs { 7452 whole 7453 gi 29423785 } , 7454 products { 7455 { 7456 type peptide , 7457 accession "AAO73561" , 7458 version 1 , 7459 source { 7460 { 7461 src { 7462 db "Protein" , 7463 tag 7464 id 29423786 } , 7465 anchor "AAO73561" } } , 7466 seqs { 7467 whole 7468 gi 29423786 } } } } , 7469 { 7470 type genomic , 7471 heading "Genomic" , 7472 accession "AY230252" , 7473 version 1 , 7474 source { 7475 { 7476 src { 7477 db "Nucleotide" , 7478 tag 7479 id 29423789 } , 7480 anchor "AY230252" } } , 7481 seqs { 7482 whole 7483 gi 29423789 } , 7484 products { 7485 { 7486 type peptide , 7487 accession "AAO73562" , 7488 version 1 , 7489 source { 7490 { 7491 src { 7492 db "Protein" , 7493 tag 7494 id 29423790 } , 7495 anchor "AAO73562" } } , 7496 seqs { 7497 whole 7498 gi 29423790 } } } } , 7499 { 7500 type genomic , 7501 heading "Genomic" , 7502 accession "AY331807" , 7503 version 1 , 7504 source { 7505 { 7506 src { 7507 db "Nucleotide" , 7508 tag 7509 id 32402490 } , 7510 anchor "AY331807" } } , 7511 seqs { 7512 whole 7513 gi 32402490 } , 7514 products { 7515 { 7516 type peptide , 7517 accession "AAP81164" , 7518 version 1 , 7519 source { 7520 { 7521 src { 7522 db "Protein" , 7523 tag 7524 id 32402491 } , 7525 anchor "AAP81164" } } , 7526 seqs { 7527 whole 7528 gi 32402491 } } } } , 7529 { 7530 type genomic , 7531 heading "Genomic" , 7532 accession "D10870" , 7533 version 1 , 7534 source { 7535 { 7536 src { 7537 db "Nucleotide" , 7538 tag 7539 id 219871 } , 7540 anchor "D10870" } } , 7541 seqs { 7542 whole 7543 gi 219871 } , 7544 products { 7545 { 7546 type peptide , 7547 accession "BAA01640" , 7548 version 1 , 7549 source { 7550 { 7551 src { 7552 db "Protein" , 7553 tag 7554 id 219872 } , 7555 anchor "BAA01640" } } , 7556 seqs { 7557 whole 7558 gi 219872 } } } } , 7559 { 7560 type genomic , 7561 heading "Genomic" , 7562 accession "D10871" , 7563 version 1 , 7564 source { 7565 { 7566 src { 7567 db "Nucleotide" , 7568 tag 7569 id 219874 } , 7570 anchor "D10871" } } , 7571 seqs { 7572 whole 7573 gi 219874 } , 7574 products { 7575 { 7576 type peptide , 7577 accession "BAA01641" , 7578 version 1 , 7579 source { 7580 { 7581 src { 7582 db "Protein" , 7583 tag 7584 id 219875 } , 7585 anchor "BAA01641" } } , 7586 seqs { 7587 whole 7588 gi 219875 } } } } , 7589 { 7590 type genomic , 7591 heading "Genomic" , 7592 accession "D10872" , 7593 version 1 , 7594 source { 7595 { 7596 src { 7597 db "Nucleotide" , 7598 tag 7599 id 219877 } , 7600 anchor "D10872" } } , 7601 seqs { 7602 whole 7603 gi 219877 } , 7604 products { 7605 { 7606 type peptide , 7607 accession "BAA01642" , 7608 version 1 , 7609 source { 7610 { 7611 src { 7612 db "Protein" , 7613 tag 7614 id 219878 } , 7615 anchor "BAA01642" } } , 7616 seqs { 7617 whole 7618 gi 219878 } } } } , 7619 { 7620 type genomic , 7621 heading "Genomic" , 7622 accession "M75163" , 7623 version 1 , 7624 source { 7625 { 7626 src { 7627 db "Nucleotide" , 7628 tag 7629 id 189075 } , 7630 anchor "M75163" } } , 7631 seqs { 7632 whole 7633 gi 189075 } , 7634 products { 7635 { 7636 type peptide , 7637 accession "AAA59906" , 7638 version 1 , 7639 source { 7640 { 7641 src { 7642 db "Protein" , 7643 tag 7644 id 553602 } , 7645 anchor "AAA59906" } } , 7646 seqs { 7647 whole 7648 gi 553602 } } } } , 7649 { 7650 type genomic , 7651 heading "Genomic" , 7652 accession "M75164" , 7653 version 1 , 7654 source { 7655 { 7656 src { 7657 db "Nucleotide" , 7658 tag 7659 id 189072 } , 7660 anchor "M75164" } } , 7661 seqs { 7662 whole 7663 gi 189072 } , 7664 products { 7665 { 7666 type peptide , 7667 accession "AAA59905" , 7668 version 1 , 7669 source { 7670 { 7671 src { 7672 db "Protein" , 7673 tag 7674 id 553601 } , 7675 anchor "AAA59905" } } , 7676 seqs { 7677 whole 7678 gi 553601 } } } } , 7679 { 7680 type genomic , 7681 heading "Genomic" , 7682 accession "U23052" , 7683 version 1 , 7684 source { 7685 { 7686 src { 7687 db "Nucleotide" , 7688 tag 7689 id 747646 } , 7690 anchor "U23052" } } , 7691 seqs { 7692 whole 7693 gi 747646 } , 7694 products { 7695 { 7696 type peptide , 7697 accession "AAA64584" , 7698 version 1 , 7699 source { 7700 { 7701 src { 7702 db "Protein" , 7703 tag 7704 id 727413 } , 7705 anchor "AAA64584" } } , 7706 seqs { 7707 whole 7708 gi 727413 } } } } , 7709 { 7710 type genomic , 7711 heading "Genomic" , 7712 accession "U23434" , 7713 version 1 , 7714 source { 7715 { 7716 src { 7717 db "Nucleotide" , 7718 tag 7719 id 727456 } , 7720 anchor "U23434" } } , 7721 seqs { 7722 whole 7723 gi 727456 } , 7724 products { 7725 { 7726 type peptide , 7727 accession "AAA64585" , 7728 version 1 , 7729 source { 7730 { 7731 src { 7732 db "Protein" , 7733 tag 7734 id 727457 } , 7735 anchor "AAA64585" } } , 7736 seqs { 7737 whole 7738 gi 727457 } } } } , 7739 { 7740 type genomic , 7741 heading "Genomic" , 7742 accession "U53473" , 7743 version 1 , 7744 source { 7745 { 7746 src { 7747 db "Nucleotide" , 7748 tag 7749 id 1297331 } , 7750 anchor "U53473" } } , 7751 seqs { 7752 whole 7753 gi 1297331 } , 7754 products { 7755 { 7756 type peptide , 7757 accession "AAA98976" , 7758 version 1 , 7759 source { 7760 { 7761 src { 7762 db "Protein" , 7763 tag 7764 id 1297332 } , 7765 anchor "AAA98976" } } , 7766 seqs { 7767 whole 7768 gi 1297332 } } } } , 7769 { 7770 type genomic , 7771 heading "Genomic" , 7772 accession "X14672" , 7773 version 1 , 7774 source { 7775 { 7776 src { 7777 db "Nucleotide" , 7778 tag 7779 id 28227 } , 7780 anchor "X14672" } } , 7781 seqs { 7782 whole 7783 gi 28227 } , 7784 products { 7785 { 7786 type peptide , 7787 accession "CAA32802" , 7788 version 1 , 7789 source { 7790 { 7791 src { 7792 db "Protein" , 7793 tag 7794 id 28228 } , 7795 anchor "CAA32802" } } , 7796 seqs { 7797 whole 7798 gi 28228 } } } } , 7799 { 7800 type mRNA , 7801 heading "mRNA" , 7802 accession "BC015878" , 7803 version 1 , 7804 source { 7805 { 7806 src { 7807 db "Nucleotide" , 7808 tag 7809 id 16198419 } , 7810 anchor "BC015878" } } , 7811 seqs { 7812 whole 7813 gi 16198419 } , 7814 products { 7815 { 7816 type peptide , 7817 accession "AAH15878" , 7818 version 1 , 7819 source { 7820 { 7821 src { 7822 db "Protein" , 7823 tag 7824 id 16198420 } , 7825 anchor "AAH15878" } } , 7826 seqs { 7827 whole 7828 gi 16198420 } } } } , 7829 { 7830 type mRNA , 7831 heading "mRNA" , 7832 accession "BC067218" , 7833 version 1 , 7834 source { 7835 { 7836 src { 7837 db "Nucleotide" , 7838 tag 7839 id 45501306 } , 7840 anchor "BC067218" } } , 7841 seqs { 7842 whole 7843 gi 45501306 } , 7844 products { 7845 { 7846 type peptide , 7847 accession "AAH67218" , 7848 version 1 , 7849 source { 7850 { 7851 src { 7852 db "Protein" , 7853 tag 7854 id 45501307 } , 7855 anchor "AAH67218" } } , 7856 seqs { 7857 whole 7858 gi 45501307 } } } } , 7859 { 7860 type mRNA , 7861 heading "mRNA" , 7862 accession "CR407631" , 7863 version 1 , 7864 source { 7865 { 7866 src { 7867 db "Nucleotide" , 7868 tag 7869 id 47115198 } , 7870 anchor "CR407631" } } , 7871 seqs { 7872 whole 7873 gi 47115198 } , 7874 products { 7875 { 7876 type peptide , 7877 accession "CAG28559" , 7878 version 1 , 7879 source { 7880 { 7881 src { 7882 db "Protein" , 7883 tag 7884 id 47115199 } , 7885 anchor "CAG28559" } } , 7886 seqs { 7887 whole 7888 gi 47115199 } } } } , 7889 { 7890 type mRNA , 7891 heading "mRNA" , 7892 accession "D90040" , 7893 version 1 , 7894 source { 7895 { 7896 src { 7897 db "Nucleotide" , 7898 tag 7899 id 219411 } , 7900 anchor "D90040" } } , 7901 seqs { 7902 whole 7903 gi 219411 } , 7904 products { 7905 { 7906 type peptide , 7907 accession "BAA14094" , 7908 version 1 , 7909 source { 7910 { 7911 src { 7912 db "Protein" , 7913 tag 7914 id 219412 } , 7915 anchor "BAA14094" } } , 7916 seqs { 7917 whole 7918 gi 219412 } } } } , 7919 { 7920 type mRNA , 7921 heading "mRNA" , 7922 accession "D90042" , 7923 version 1 , 7924 source { 7925 { 7926 src { 7927 db "Nucleotide" , 7928 tag 7929 id 219415 } , 7930 anchor "D90042" } } , 7931 seqs { 7932 whole 7933 gi 219415 } , 7934 products { 7935 { 7936 type peptide , 7937 accession "BAA14096" , 7938 version 1 , 7939 source { 7940 { 7941 src { 7942 db "Protein" , 7943 tag 7944 id 219416 } , 7945 anchor "BAA14096" } } , 7946 seqs { 7947 whole 7948 gi 219416 } } } } , 7949 { 7950 type other , 7951 text "None" , 7952 version 0 , 7953 products { 7954 { 7955 type peptide , 7956 accession "P11245" , 7957 version 0 , 7958 source { 7959 { 7960 src { 7961 db "Protein" , 7962 tag 7963 id 114238 } , 7964 anchor "P11245" } } , 7965 seqs { 7966 whole 7967 gi 114238 } } } } } } , 7968 { 7969 type comment , 7970 heading "Additional Links" , 7971 version 0 , 7972 comment { 7973 { 7974 type comment , 7975 version 0 , 7976 source { 7977 { 7978 src { 7979 db "Evidence Viewer" , 7980 tag 7981 str "10" } , 7982 anchor "Evidence Viewer" , 7983 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 7984g=NT_030737.9&gene=NAT2&lid=10&from=6093683&to=6103610" } } } , 7985 { 7986 type comment , 7987 version 0 , 7988 source { 7989 { 7990 src { 7991 db "ModelMaker" , 7992 tag 7993 str "10" } , 7994 anchor "ModelMaker" , 7995 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 799606&contig=NT_030737.9&gene=NAT2&lid=10" } } } , 7997 { 7998 type comment , 7999 text "UniGene" , 8000 version 0 , 8001 xtra-properties { 8002 { 8003 tag "UNIGENE" , 8004 value "Hs.2" } } , 8005 source { 8006 { 8007 src { 8008 db "UniGene" , 8009 tag 8010 str "Hs.2" } , 8011 anchor "Hs.2" , 8012 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=2" } } } , 8013 { 8014 type comment , 8015 text "MIM" , 8016 version 0 , 8017 source { 8018 { 8019 src { 8020 db "MIM" , 8021 tag 8022 str "243400" } , 8023 anchor "243400" } } } , 8024 { 8025 type comment , 8026 version 0 , 8027 source { 8028 { 8029 src { 8030 db "AceView" , 8031 tag 8032 id 10 } , 8033 anchor "AceView" , 8034 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 8035ocusid&org=9606&l=10" } } } , 8036 { 8037 type comment , 8038 version 0 , 8039 source { 8040 { 8041 src { 8042 db "GDB" , 8043 tag 8044 str "GDB:125365" } } } } , 8045 { 8046 type comment , 8047 version 0 , 8048 source { 8049 { 8050 src { 8051 db "Ensembl" , 8052 tag 8053 str "" } , 8054 url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=BC067 8055218" } } } , 8056 { 8057 type comment , 8058 version 0 , 8059 source { 8060 { 8061 src { 8062 db "UCSC" , 8063 tag 8064 str "" } , 8065 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position= 8066BC067218" } } } , 8067 { 8068 type comment , 8069 text "PharmGKB" , 8070 version 0 , 8071 source { 8072 { 8073 src { 8074 db "PharmGKB" , 8075 tag 8076 str "PA18" } , 8077 anchor "PA18" } } } , 8078 { 8079 type comment , 8080 text "Arylamine N-Acetyltransferase Nomenclature" , 8081 version 0 , 8082 source { 8083 { 8084 src { 8085 db "Arylamine N-Acetyltransferase Nomenclature" , 8086 tag 8087 str "Arylamine N-Acetyltransferase Nomenclature" } , 8088 anchor "Arylamine N-Acetyltransferase Nomenclature" , 8089 url "http://www.louisville.edu/medschool/pharmacology/NAT.html" } } } , 8090 { 8091 type comment , 8092 version 0 , 8093 source { 8094 { 8095 src { 8096 db "MGC" , 8097 tag 8098 str "BC015878,BC067218" } , 8099 anchor "MGC" , 8100 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC015878 8101,BC067218" } } } } } , 8102 { 8103 type generif , 8104 text "there is no association between endometriosis and NAT2 in South 8105 Indian women" , 8106 version 0 , 8107 refs { 8108 pmid 15588473 } , 8109 create-date 8110 str "Mar 19 2005 10:01AM" , 8111 update-date 8112 str "Mar 19 2005 11:47AM" } , 8113 { 8114 type generif , 8115 text "Risks for colorectal cancer are significantly associated with the 8116 genetic polymorphisms of GSTT1 deletion, NAT2-rapid acetylator phenotype and 8117 genotye and NAT2-rapid acetylator phenotype." , 8118 version 0 , 8119 refs { 8120 pmid 15637738 } , 8121 create-date 8122 str "Mar 7 2005 7:07PM" , 8123 update-date 8124 str "Mar 8 2005 12:10AM" } , 8125 { 8126 type generif , 8127 text "Cigarette smoking is associated with increased risk of breast 8128 cancer in women with the NAT2 slow acetylator genotype." , 8129 version 0 , 8130 refs { 8131 pmid 15225898 } , 8132 create-date 8133 str "Nov 13 2004 10:01AM" , 8134 update-date 8135 str "Nov 13 2004 10:50AM" } , 8136 { 8137 type generif , 8138 text "N-acetyltransferase 2 polymorphism does not play an important role 8139 in breast cancer risk of Turkish women by altering the capacity in 8140 deactivation of environmental carcinogens" , 8141 version 0 , 8142 refs { 8143 pmid 15162844 } , 8144 create-date 8145 str "Oct 4 2004 10:33AM" , 8146 update-date 8147 str "Oct 4 2004 11:19AM" } , 8148 { 8149 type generif , 8150 text "NAT2 slow acetylator genotypes might modulate the effect of 8151 carcinogenic arylamines contained in tobacco smoke." , 8152 version 0 , 8153 refs { 8154 pmid 14648207 } , 8155 create-date 8156 str "Sep 27 2004 4:34PM" , 8157 update-date 8158 str "Sep 27 2004 5:11PM" } , 8159 { 8160 type generif , 8161 text "Arylamine N-acetyltransferase 2 is a genetically polymorphic phase 8162 II enzyme with a role in the metabolism of many xenobiotics." , 8163 version 0 , 8164 refs { 8165 pmid 14747882 } , 8166 create-date 8167 str "Aug 2 2004 1:09PM" , 8168 update-date 8169 str "Aug 2 2004 1:38PM" } , 8170 { 8171 type generif , 8172 text "although there is little overall association between NAT genotypes 8173 and risk of developing systemic lupus erythematosus, the interaction between 8174 NAT1 and NAT2 and specific exposures such as hair dyes may be important" , 8175 version 0 , 8176 refs { 8177 pmid 14705222 } , 8178 create-date 8179 str "Apr 16 2004 12:00AM" , 8180 update-date 8181 str "May 2 2004 7:01AM" } , 8182 { 8183 type generif , 8184 text "The NAT2 acetylator genotype may modify esophageal cancer risk in 8185 humans from exposure to barbecued/grilled meat." , 8186 version 0 , 8187 refs { 8188 pmid 12773763 } , 8189 create-date 8190 str "Feb 13 2004 12:00AM" , 8191 update-date 8192 str "Feb 22 2004 7:01AM" } , 8193 { 8194 type generif , 8195 text "N-acetyltransferase 2 polymorphism does not differ between 8196 patients suffering from atopic dermatitis and healthy subjects" , 8197 version 0 , 8198 refs { 8199 pmid 14528063 } , 8200 create-date 8201 str "Feb 5 2004 12:00AM" , 8202 update-date 8203 str "Feb 15 2004 6:33PM" } , 8204 { 8205 type generif , 8206 text "Genetic NAT2 polymorphism may play a role in lifestyle 8207 factors-related hepato- carcinogenesis, particulary critical in smoking 8208 related hepatocarcinogenesis." , 8209 version 0 , 8210 refs { 8211 pmid 12877350 } , 8212 create-date 8213 str "Feb 4 2004 12:00AM" , 8214 update-date 8215 str "Feb 15 2004 6:32PM" } , 8216 { 8217 type generif , 8218 text "Slow acetylation activity is associated with age-related cataract 8219 formation." , 8220 version 0 , 8221 refs { 8222 pmid 12724621 } , 8223 create-date 8224 str "Jan 6 2004 12:00AM" , 8225 update-date 8226 str "Feb 22 2004 7:01AM" } , 8227 { 8228 type generif , 8229 text "A significant association between Parkinson disease & the slow 8230 acetylator genotype for N-acetyltransferase 2 in Hong Kong Chinesed provides 8231 evidence for a possible functional relationship between NAT2 slow acetylator 8232 genotype & PD in both racial groups." , 8233 version 0 , 8234 refs { 8235 pmid 12654968 } , 8236 create-date 8237 str "Dec 23 2003 12:00AM" , 8238 update-date 8239 str "Jan 18 2004 7:01AM" } , 8240 { 8241 type generif , 8242 text "RFLP of the gene coding for N-acetyltransferase 2 (NAT2) was typed 8243 in populations of the Volga-Ural region (Bashkirs, Tatars, Chuvashes, 8244 Udmurts, and Russians) and in patients with chronic obstructive pulmonary 8245 disease (COPD) and in healthy individuals" , 8246 version 0 , 8247 refs { 8248 pmid 12884528 } , 8249 create-date 8250 str "Dec 18 2003 12:00AM" , 8251 update-date 8252 str "Jan 25 2004 7:01AM" } , 8253 { 8254 type generif , 8255 text "We conclude that smoking increases risk of colorectal adenomas and 8256 that SULT1A1 and NAT2 only modestly modify this association." , 8257 version 0 , 8258 refs { 8259 pmid 14618622 } , 8260 create-date 8261 str "Dec 11 2003 12:00AM" , 8262 update-date 8263 str "Dec 21 2003 7:01AM" } , 8264 { 8265 type generif , 8266 text "In human, NAT2 polymorphism may be a genetic risk factor for joint 8267 destruction." , 8268 version 0 , 8269 refs { 8270 pmid 15005011 } , 8271 create-date 8272 str "May 7 2004 12:00AM" , 8273 update-date 8274 str "May 16 2004 7:01AM" } , 8275 { 8276 type generif , 8277 text "It is unlikely that the NAT1*10 or NAT2 rapid/intermediate 8278 genotypes are related to stomach cancer risk." , 8279 version 0 , 8280 refs { 8281 pmid 12692115 } , 8282 create-date 8283 str "Sep 4 2003 12:00AM" , 8284 update-date 8285 str "Sep 28 2003 7:01AM" } , 8286 { 8287 type generif , 8288 text "genetic polymorphisms of NAT1 and NAT2 have no independent effect 8289 on breast cancer risk, but they modulate breast cancer risk in the presence 8290 of GSTM1 and GSTT1 null genotypes." , 8291 version 0 , 8292 refs { 8293 pmid 12860276 } , 8294 create-date 8295 str "Aug 18 2003 12:00AM" , 8296 update-date 8297 str "Aug 24 2003 7:01AM" } , 8298 { 8299 type generif , 8300 text "NAT2 slow acetylator genotype plays an important role in 8301 determining the risk of developing prostate cancer in Japanese men and is 8302 also associated with more clinically advanced and pathologically aggressive 8303 disease." , 8304 version 0 , 8305 refs { 8306 pmid 12622714 } , 8307 create-date 8308 str "Aug 9 2003 12:00AM" , 8309 update-date 8310 str "Aug 24 2003 7:01AM" } , 8311 { 8312 type generif , 8313 text "Polymorphism of Nat2 encoding phase 2 xenobiotic detoxication 8314 enzyme was studied." , 8315 version 0 , 8316 refs { 8317 pmid 12760253 } , 8318 create-date 8319 str "Jun 26 2003 12:00AM" , 8320 update-date 8321 str "Aug 10 2003 7:01AM" } , 8322 { 8323 type generif , 8324 text "This enzyme is polymorphic in various ethnic populations of South 8325 India." , 8326 version 0 , 8327 refs { 8328 pmid 12469231 } , 8329 create-date 8330 str "May 24 2003 12:00AM" , 8331 update-date 8332 str "Jul 27 2003 7:01AM" } , 8333 { 8334 type generif , 8335 text "Maternal NAT2 acetylator status seems not to be an important 8336 factor in the etiology of orofacial clefts." , 8337 version 0 , 8338 refs { 8339 pmid 12397635 } , 8340 create-date 8341 str "May 7 2003 12:00AM" , 8342 update-date 8343 str "Jun 1 2003 7:01AM" } , 8344 { 8345 type generif , 8346 text "Genotyping the NAT2 gene and estimating diplotype configuration 8347 before administration of SSZ may reduce the frequency of adverse effects in 8348 Japanese patients with RA." , 8349 version 0 , 8350 refs { 8351 pmid 12465141 } , 8352 create-date 8353 str "May 2 2003 12:00AM" , 8354 update-date 8355 str "May 11 2003 7:01AM" } , 8356 { 8357 type generif , 8358 text "Single nucleotide polymorphisms of NAT1 and NAT2, and acetylation 8359 haplotype were not associated with increased risk for Parkinson disease" , 8360 version 0 , 8361 refs { 8362 pmid 12682333 } , 8363 create-date 8364 str "Apr 11 2003 12:00AM" , 8365 update-date 8366 str "Apr 27 2003 7:01AM" } , 8367 { 8368 type generif , 8369 text "lack of association between polymorphism of this gene and systemic 8370 lupus erythematosus" , 8371 version 0 , 8372 refs { 8373 pmid 12360107 } , 8374 create-date 8375 str "Apr 9 2003 12:00AM" , 8376 update-date 8377 str "Apr 27 2003 7:01AM" } , 8378 { 8379 type generif , 8380 text "Polymorphic N-acetyltransferase (NAT2) is involved in the 8381 metabolism of several compounds relevant in pharmacology or toxicology, with 8382 diverse clinical consequences--review" , 8383 version 0 , 8384 refs { 8385 pmid 12611196 } , 8386 create-date 8387 str "Mar 24 2003 12:00AM" , 8388 update-date 8389 str "Mar 31 2003 6:30AM" } , 8390 { 8391 type generif , 8392 text "N-acetyltransferase 2*19 possessing the C190T (R64W) single 8393 nucleotide polymorphisms encodes a slow acetylator phenotype for both N- and 8394 O-acetylation, due to a reduction in the amount and stability of the NAT2 19 8395 allozyme" , 8396 version 0 , 8397 refs { 8398 pmid 12222688 } , 8399 create-date 8400 str "Mar 10 2003 12:00AM" , 8401 update-date 8402 str "Apr 13 2003 7:01AM" } , 8403 { 8404 type generif , 8405 text "NAT2 slow acetylation and GSTM1 null genotypes may increase 8406 postmenopausal breast cancer risk in long-term smoking women." , 8407 version 0 , 8408 refs { 8409 pmid 12835615 } , 8410 create-date 8411 str "Mar 7 2004 12:00AM" , 8412 update-date 8413 str "Apr 18 2004 7:02AM" } , 8414 { 8415 type generif , 8416 text "A slow acetylator genotype of this enzyme is associated with an 8417 increased risk of advanced cervical cancer." , 8418 version 0 , 8419 refs { 8420 pmid 12474054 } , 8421 create-date 8422 str "Feb 27 2003 12:00AM" , 8423 update-date 8424 str "Apr 13 2003 7:01AM" } , 8425 { 8426 type generif , 8427 text "Women with the GSTT1 null genotype were found to have a 8428 significant 3.15-fold increased risk of breast cancer (95% CI = 1.7-5.8), 8429 while GSTM1 and NAT2 genotypes were not associated with breast cancer risk." , 8430 version 0 , 8431 refs { 8432 pmid 12430181 } , 8433 create-date 8434 str "Nov 25 2002 12:00AM" , 8435 update-date 8436 str "Feb 2 2003 7:01AM" } , 8437 { 8438 type generif , 8439 text "NAT2 slow genotype with NAT1 polymorphism indicates increased 8440 susceptibility to prostate cancer" , 8441 version 0 , 8442 refs { 8443 pmid 12355549 } , 8444 create-date 8445 str "Oct 31 2002 12:00AM" , 8446 update-date 8447 str "Feb 2 2003 7:01AM" } , 8448 { 8449 type generif , 8450 text "NAT2 slow acetylation genotype may be a risk factor of individual 8451 susceptibility to rheumatoid arthritis." , 8452 version 0 , 8453 refs { 8454 pmid 12235453 } , 8455 create-date 8456 str "Oct 7 2002 12:00AM" , 8457 update-date 8458 str "Feb 2 2003 7:01AM" } , 8459 { 8460 type generif , 8461 text "NAT2 acetylator status can influence susceptibility to breast 8462 cancer after exposure to tobacco smoke carcinogens; effect appears to be 8463 differential for active and passive smoke exposure" , 8464 version 0 , 8465 refs { 8466 pmid 12163321 } , 8467 create-date 8468 str "Sep 7 2002 12:00AM" , 8469 update-date 8470 str "Sep 16 2002 5:48AM" } , 8471 { 8472 type generif , 8473 text "NAT2 polymorphisms may be correlated with an increased risk of 8474 larynx cancer" , 8475 version 0 , 8476 refs { 8477 pmid 12037388 } , 8478 create-date 8479 str "Aug 19 2002 12:00AM" , 8480 update-date 8481 str "Aug 28 2002 6:15PM" } , 8482 { 8483 type generif , 8484 text "The combined effect of N-acetyltransferase 2 (NAT2) slow genotype 8485 and exposure to smoking is observed during the development of laryngeal 8486 cancer." , 8487 version 0 , 8488 refs { 8489 pmid 12015038 } , 8490 create-date 8491 str "Aug 9 2002 12:00AM" , 8492 update-date 8493 str "Sep 16 2002 5:48AM" } , 8494 { 8495 type generif , 8496 text "urinary excretion of 8497 N(2)-(beta-1-glucos-iduronyl)-2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]p 8498yridine relationship to activity levels of NAT2" , 8499 version 0 , 8500 refs { 8501 pmid 12016157 } , 8502 create-date 8503 str "Jun 12 2002 12:00AM" , 8504 update-date 8505 str "Jun 24 2002 6:31AM" } , 8506 { 8507 type generif , 8508 text "Polymorphism of the N-acetyltransferase 2 gene as a susceptibility 8509 risk factor for antituberculosis drug-induced hepatitis." , 8510 version 0 , 8511 refs { 8512 pmid 11915035 } , 8513 create-date 8514 str "Apr 15 2002 12:00AM" , 8515 update-date 8516 str "Apr 28 2002 6:17PM" } , 8517 { 8518 type generif , 8519 text "Association between bone loss in periodontal disease and 8520 polymorphism of N-acetyltransferase (NAT2)" , 8521 version 0 , 8522 refs { 8523 pmid 11846845 } , 8524 create-date 8525 str "Apr 9 2002 12:00AM" , 8526 update-date 8527 str "May 14 2002 5:48AM" } , 8528 { 8529 type generif , 8530 text "we investigated the relationship between the levels of aromatic 8531 DNA adducts in breast tissues and polymorphisms of the drug-metabolizing 8532 genes CYP1A1, NAT2, and GSTM1 in 166 women having breast cancer" , 8533 version 0 , 8534 refs { 8535 pmid 11872636 } , 8536 create-date 8537 str "Apr 2 2002 12:00AM" , 8538 update-date 8539 str "Apr 8 2002 3:24PM" } } , 8540 unique-keys { 8541 { 8542 db "LocusID" , 8543 tag 8544 id 10 } , 8545 { 8546 db "MIM" , 8547 tag 8548 id 243400 } } , 8549 xtra-index-terms { 8550 "LOC10" } } 8551Entrezgene ::= { 8552 track-info { 8553 geneid 11 , 8554 status live , 8555 create-date 8556 std { 8557 year 2003 , 8558 month 8 , 8559 day 28 , 8560 hour 20 , 8561 minute 30 , 8562 second 0 } , 8563 update-date 8564 std { 8565 year 2005 , 8566 month 3 , 8567 day 5 , 8568 hour 11 , 8569 minute 30 , 8570 second 0 } } , 8571 type pseudo , 8572 source { 8573 genome genomic , 8574 origin natural , 8575 org { 8576 taxname "Homo sapiens" , 8577 common "human" , 8578 db { 8579 { 8580 db "taxon" , 8581 tag 8582 id 9606 } } , 8583 syn { 8584 "man" } , 8585 orgname { 8586 name 8587 binomial { 8588 genus "Homo" , 8589 species "sapiens" } , 8590 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 8591 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 8592 Hominidae; Homo" , 8593 gcode 1 , 8594 mgcode 2 , 8595 div "PRI" } } , 8596 subtype { 8597 { 8598 subtype chromosome , 8599 name "8" } } } , 8600 gene { 8601 locus "AACP" , 8602 desc "arylamide acetylase pseudogene" , 8603 maploc "8p22" , 8604 syn { 8605 "NATP" } , 8606 locus-tag "HGNC:15" } , 8607 location { 8608 { 8609 display-str "8p22" , 8610 method 8611 map-type cyto } } , 8612 gene-source { 8613 src "LocusLink" , 8614 src-int 11 , 8615 src-str2 "11" , 8616 gene-display FALSE , 8617 locus-display FALSE , 8618 extra-terms FALSE } , 8619 locus { 8620 { 8621 type genomic , 8622 version 0 } } , 8623 properties { 8624 { 8625 type comment , 8626 label "Nomenclature" , 8627 version 0 , 8628 source { 8629 { 8630 anchor "HUGO Gene Nomenclature Committee" } } , 8631 properties { 8632 { 8633 type property , 8634 label "Official Symbol" , 8635 text "AACP" , 8636 version 0 } , 8637 { 8638 type property , 8639 label "Official Full Name" , 8640 text "arylamide acetylase pseudogene" , 8641 version 0 } } } } , 8642 comments { 8643 { 8644 type comment , 8645 heading "LocusTagLink" , 8646 version 0 , 8647 source { 8648 { 8649 src { 8650 db "HGNC" , 8651 tag 8652 id 15 } } } } , 8653 { 8654 type comment , 8655 version 0 , 8656 refs { 8657 pmid 2340091 } } , 8658 { 8659 type comment , 8660 heading "Related Sequences" , 8661 version 0 , 8662 products { 8663 { 8664 type genomic , 8665 heading "Genomic" , 8666 accession "X17060" , 8667 version 1 , 8668 source { 8669 { 8670 src { 8671 db "Nucleotide" , 8672 tag 8673 id 34995 } , 8674 anchor "X17060" } } , 8675 seqs { 8676 whole 8677 gi 34995 } , 8678 products { 8679 { 8680 type peptide , 8681 text "None" , 8682 version 0 } } } } } , 8683 { 8684 type comment , 8685 heading "Additional Links" , 8686 version 0 , 8687 comment { 8688 { 8689 type comment , 8690 version 0 , 8691 source { 8692 { 8693 src { 8694 db "GDB" , 8695 tag 8696 str "GDB:132838" } } } } } } } , 8697 unique-keys { 8698 { 8699 db "LocusID" , 8700 tag 8701 id 11 } } , 8702 xtra-index-terms { 8703 "LOC11" } } 8704Entrezgene ::= { 8705 track-info { 8706 geneid 12 , 8707 status live , 8708 create-date 8709 std { 8710 year 2003 , 8711 month 8 , 8712 day 28 , 8713 hour 20 , 8714 minute 30 , 8715 second 0 } , 8716 update-date 8717 std { 8718 year 2005 , 8719 month 4 , 8720 day 14 , 8721 hour 13 , 8722 minute 15 , 8723 second 0 } } , 8724 type protein-coding , 8725 source { 8726 genome genomic , 8727 origin natural , 8728 org { 8729 taxname "Homo sapiens" , 8730 common "human" , 8731 db { 8732 { 8733 db "taxon" , 8734 tag 8735 id 9606 } } , 8736 syn { 8737 "man" } , 8738 orgname { 8739 name 8740 binomial { 8741 genus "Homo" , 8742 species "sapiens" } , 8743 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 8744 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 8745 Hominidae; Homo" , 8746 gcode 1 , 8747 mgcode 2 , 8748 div "PRI" } } , 8749 subtype { 8750 { 8751 subtype chromosome , 8752 name "14" } } } , 8753 gene { 8754 locus "SERPINA3" , 8755 desc "serine (or cysteine) proteinase inhibitor, clade A (alpha-1 8756 antiproteinase, antitrypsin), member 3" , 8757 maploc "14q32.1" , 8758 db { 8759 { 8760 db "MIM" , 8761 tag 8762 id 107280 } } , 8763 syn { 8764 "ACT" , 8765 "AACT" , 8766 "MGC88254" } , 8767 locus-tag "HGNC:16" } , 8768 prot { 8769 name { 8770 "serine (or cysteine) proteinase inhibitor, clade A, member 3" , 8771 "antichymotrypsin" , 8772 "alpha-1-antichymotrypsin" , 8773 "serine (or cysteine) proteinase inhibitor, clade A, member 3" } } , 8774 summary "The protein encoded by this gene is a plasma protease inhibitor and 8775 member of the serine protease inhibitor class. Polymorphisms in this protein 8776 appear to be tissue specific and influence protease targeting. Variation in 8777 this protein's sequence have been implicated in Alzheimer's disease, and 8778 deficiency of this protein has been associated with liver disease. Mutations 8779 have been identified in patients with Parkinson disease and chronic 8780 obstructive pulmonary disease." , 8781 location { 8782 { 8783 display-str "14q32.1" , 8784 method 8785 map-type cyto } } , 8786 gene-source { 8787 src "LocusLink" , 8788 src-int 12 , 8789 src-str2 "12" , 8790 gene-display FALSE , 8791 locus-display FALSE , 8792 extra-terms FALSE } , 8793 locus { 8794 { 8795 type genomic , 8796 heading "Reference" , 8797 accession "NC_000014" , 8798 version 7 , 8799 seqs { 8800 int { 8801 from 94150523 , 8802 to 94160143 , 8803 strand plus , 8804 id 8805 gi 51511730 } } , 8806 products { 8807 { 8808 type mRNA , 8809 heading "Reference" , 8810 accession "NM_001085" , 8811 version 2 , 8812 genomic-coords { 8813 mix { 8814 int { 8815 from 94150523 , 8816 to 94151173 , 8817 strand plus , 8818 id 8819 gi 51511730 } , 8820 int { 8821 from 94155284 , 8822 to 94155557 , 8823 strand plus , 8824 id 8825 gi 51511730 } , 8826 int { 8827 from 94158430 , 8828 to 94158580 , 8829 strand plus , 8830 id 8831 gi 51511730 } , 8832 int { 8833 from 94159700 , 8834 to 94160143 , 8835 strand plus , 8836 id 8837 gi 51511730 } } } , 8838 seqs { 8839 whole 8840 gi 9665246 } , 8841 products { 8842 { 8843 type peptide , 8844 heading "Reference" , 8845 label "precursor" , 8846 accession "NP_001076" , 8847 version 1 , 8848 genomic-coords { 8849 packed-int { 8850 { 8851 from 94150531 , 8852 to 94151173 , 8853 strand plus , 8854 id 8855 gi 51511730 } , 8856 { 8857 from 94155284 , 8858 to 94155557 , 8859 strand plus , 8860 id 8861 gi 51511730 } , 8862 { 8863 from 94158430 , 8864 to 94158580 , 8865 strand plus , 8866 id 8867 gi 51511730 } , 8868 { 8869 from 94159700 , 8870 to 94159935 , 8871 strand plus , 8872 id 8873 gi 51511730 } } } , 8874 seqs { 8875 whole 8876 gi 4501843 } } } } } } , 8877 { 8878 type genomic , 8879 heading "Reference" , 8880 accession "NT_026437" , 8881 version 11 , 8882 seqs { 8883 int { 8884 from 76080523 , 8885 to 76090143 , 8886 strand plus , 8887 id 8888 gi 51493278 } } , 8889 products { 8890 { 8891 type mRNA , 8892 heading "Reference" , 8893 accession "NM_001085" , 8894 version 2 , 8895 genomic-coords { 8896 mix { 8897 int { 8898 from 76080523 , 8899 to 76081173 , 8900 strand plus , 8901 id 8902 gi 51493278 } , 8903 int { 8904 from 76085284 , 8905 to 76085557 , 8906 strand plus , 8907 id 8908 gi 51493278 } , 8909 int { 8910 from 76088430 , 8911 to 76088580 , 8912 strand plus , 8913 id 8914 gi 51493278 } , 8915 int { 8916 from 76089700 , 8917 to 76090143 , 8918 strand plus , 8919 id 8920 gi 51493278 } } } , 8921 seqs { 8922 whole 8923 gi 9665246 } , 8924 products { 8925 { 8926 type peptide , 8927 heading "Reference" , 8928 label "precursor" , 8929 accession "NP_001076" , 8930 version 1 , 8931 genomic-coords { 8932 packed-int { 8933 { 8934 from 76080531 , 8935 to 76081173 , 8936 strand plus , 8937 id 8938 gi 51493278 } , 8939 { 8940 from 76085284 , 8941 to 76085557 , 8942 strand plus , 8943 id 8944 gi 51493278 } , 8945 { 8946 from 76088430 , 8947 to 76088580 , 8948 strand plus , 8949 id 8950 gi 51493278 } , 8951 { 8952 from 76089700 , 8953 to 76089935 , 8954 strand plus , 8955 id 8956 gi 51493278 } } } , 8957 seqs { 8958 whole 8959 gi 4501843 } } } } } } , 8960 { 8961 type genomic , 8962 heading "Reference" , 8963 accession "NT_086807" , 8964 version 1 , 8965 seqs { 8966 int { 8967 from 23153523 , 8968 to 23163143 , 8969 strand plus , 8970 id 8971 gi 51472322 } } , 8972 products { 8973 { 8974 type mRNA , 8975 heading "Reference" , 8976 accession "NM_001085" , 8977 version 2 , 8978 genomic-coords { 8979 mix { 8980 int { 8981 from 23153523 , 8982 to 23154173 , 8983 strand plus , 8984 id 8985 gi 51472322 } , 8986 int { 8987 from 23158284 , 8988 to 23158557 , 8989 strand plus , 8990 id 8991 gi 51472322 } , 8992 int { 8993 from 23161430 , 8994 to 23161580 , 8995 strand plus , 8996 id 8997 gi 51472322 } , 8998 int { 8999 from 23162700 , 9000 to 23163143 , 9001 strand plus , 9002 id 9003 gi 51472322 } } } , 9004 seqs { 9005 whole 9006 gi 9665246 } , 9007 products { 9008 { 9009 type peptide , 9010 heading "Reference" , 9011 label "precursor" , 9012 accession "NP_001076" , 9013 version 1 , 9014 genomic-coords { 9015 packed-int { 9016 { 9017 from 23153531 , 9018 to 23154173 , 9019 strand plus , 9020 id 9021 gi 51472322 } , 9022 { 9023 from 23158284 , 9024 to 23158557 , 9025 strand plus , 9026 id 9027 gi 51472322 } , 9028 { 9029 from 23161430 , 9030 to 23161580 , 9031 strand plus , 9032 id 9033 gi 51472322 } , 9034 { 9035 from 23162700 , 9036 to 23162935 , 9037 strand plus , 9038 id 9039 gi 51472322 } } } , 9040 seqs { 9041 whole 9042 gi 4501843 } } } } } } } , 9043 properties { 9044 { 9045 type comment , 9046 label "Nomenclature" , 9047 version 0 , 9048 source { 9049 { 9050 anchor "HUGO Gene Nomenclature Committee" } } , 9051 properties { 9052 { 9053 type property , 9054 label "Official Symbol" , 9055 text "SERPINA3" , 9056 version 0 } , 9057 { 9058 type property , 9059 label "Official Full Name" , 9060 text "serine (or cysteine) proteinase inhibitor, clade A (alpha-1 9061 antiproteinase, antitrypsin), member 3" , 9062 version 0 } } } , 9063 { 9064 type comment , 9065 heading "GeneOntology" , 9066 version 0 , 9067 source { 9068 { 9069 pre-text "Provided by" , 9070 anchor "GOA" , 9071 url "http://www.ebi.ac.uk/GOA/" } } , 9072 comment { 9073 { 9074 type comment , 9075 label "Function" , 9076 version 0 , 9077 comment { 9078 { 9079 type comment , 9080 version 0 , 9081 refs { 9082 pmid 9880565 } , 9083 source { 9084 { 9085 src { 9086 db "GO" , 9087 tag 9088 id 3677 } , 9089 anchor "DNA binding" , 9090 post-text "evidence: IC" } } } , 9091 { 9092 type comment , 9093 version 0 , 9094 refs { 9095 pmid 9880565 } , 9096 source { 9097 { 9098 src { 9099 db "GO" , 9100 tag 9101 id 30569 } , 9102 anchor "chymotrypsin inhibitor activity" , 9103 post-text "evidence: NAS" } } } , 9104 { 9105 type comment , 9106 version 0 , 9107 refs { 9108 pmid 12709365 } , 9109 source { 9110 { 9111 src { 9112 db "GO" , 9113 tag 9114 id 5515 } , 9115 anchor "protein binding" , 9116 post-text "evidence: IPI" } } } , 9117 { 9118 type comment , 9119 version 0 , 9120 source { 9121 { 9122 src { 9123 db "GO" , 9124 tag 9125 id 4867 } , 9126 anchor "serine-type endopeptidase inhibitor activity" , 9127 post-text "evidence: IEA" } } } } } , 9128 { 9129 type comment , 9130 label "Process" , 9131 version 0 , 9132 comment { 9133 { 9134 type comment , 9135 version 0 , 9136 source { 9137 { 9138 src { 9139 db "GO" , 9140 tag 9141 id 6953 } , 9142 anchor "acute-phase response" , 9143 post-text "evidence: IEA" } } } , 9144 { 9145 type comment , 9146 version 0 , 9147 refs { 9148 pmid 12475184 } , 9149 source { 9150 { 9151 src { 9152 db "GO" , 9153 tag 9154 id 6954 } , 9155 anchor "inflammatory response" , 9156 post-text "evidence: NAS" } } } , 9157 { 9158 type comment , 9159 version 0 , 9160 refs { 9161 pmid 11835318 } , 9162 source { 9163 { 9164 src { 9165 db "GO" , 9166 tag 9167 id 19216 } , 9168 anchor "regulation of lipid metabolism" , 9169 post-text "evidence: NAS" } } } , 9170 { 9171 type comment , 9172 version 0 , 9173 source { 9174 { 9175 src { 9176 db "GO" , 9177 tag 9178 id 6810 } , 9179 anchor "transport" , 9180 post-text "evidence: IEA" } } } } } , 9181 { 9182 type comment , 9183 label "Component" , 9184 version 0 , 9185 comment { 9186 { 9187 type comment , 9188 version 0 , 9189 refs { 9190 pmid 9880565 , 9191 pmid 14718574 } , 9192 source { 9193 { 9194 src { 9195 db "GO" , 9196 tag 9197 id 5576 } , 9198 anchor "extracellular region" , 9199 post-text "evidence: NAS" } } } , 9200 { 9201 type comment , 9202 version 0 , 9203 refs { 9204 pmid 9880565 } , 9205 source { 9206 { 9207 src { 9208 db "GO" , 9209 tag 9210 id 5622 } , 9211 anchor "intracellular" , 9212 post-text "evidence: NAS" } } } , 9213 { 9214 type comment , 9215 version 0 , 9216 source { 9217 { 9218 src { 9219 db "GO" , 9220 tag 9221 id 5634 } , 9222 anchor "nucleus" , 9223 post-text "evidence: IEA" } } } } } } } } , 9224 homology { 9225 { 9226 type comment , 9227 heading "Mouse, Rat" , 9228 version 0 , 9229 source { 9230 { 9231 src { 9232 db "HomoloGene" , 9233 tag 9234 id 40658 } , 9235 anchor "Map Viewer" , 9236 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=14& 9237MAPS=genes-r-org/rat-chr/human%3A14,genes-r-org/mouse-chr/human%3A14,genes-r-o 9238rg/human-chr14&query=e%3A12[id]+AND+gene[obj_type]&QSTR=serpina3&cmd=focus&fil 9239l=10" } } } } , 9240 comments { 9241 { 9242 type comment , 9243 heading "LocusTagLink" , 9244 version 0 , 9245 source { 9246 { 9247 src { 9248 db "HGNC" , 9249 tag 9250 id 16 } } } } , 9251 { 9252 type comment , 9253 heading "RefSeq Status" , 9254 label "REVIEWED" , 9255 version 0 } , 9256 { 9257 type comment , 9258 version 0 , 9259 refs { 9260 pmid 15546506 , 9261 pmid 15542006 , 9262 pmid 15530656 , 9263 pmid 15014966 , 9264 pmid 14718574 , 9265 pmid 14702039 , 9266 pmid 14668352 , 9267 pmid 12709365 , 9268 pmid 12600202 , 9269 pmid 12477932 , 9270 pmid 12475184 , 9271 pmid 12324297 , 9272 pmid 12023832 , 9273 pmid 11992569 , 9274 pmid 11959399 , 9275 pmid 11936240 , 9276 pmid 11835318 , 9277 pmid 11798857 , 9278 pmid 11735417 , 9279 pmid 11692021 , 9280 pmid 11317942 , 9281 pmid 11289720 , 9282 pmid 11274154 , 9283 pmid 11096092 , 9284 pmid 10829039 , 9285 pmid 10759471 , 9286 pmid 10660528 , 9287 pmid 10512690 , 9288 pmid 10228625 , 9289 pmid 10048303 , 9290 pmid 9880565 , 9291 pmid 9824262 , 9292 pmid 9698370 , 9293 pmid 9635374 , 9294 pmid 9580375 , 9295 pmid 9428387 , 9296 pmid 9261179 , 9297 pmid 9042371 , 9298 pmid 8849841 , 9299 pmid 8739078 , 9300 pmid 8732755 , 9301 pmid 8718849 , 9302 pmid 8376411 , 9303 pmid 8365378 , 9304 pmid 8267879 , 9305 pmid 8244391 , 9306 pmid 8226889 , 9307 pmid 8216224 , 9308 pmid 8011628 , 9309 pmid 7966721 , 9310 pmid 7924407 , 9311 pmid 7873202 , 9312 pmid 7759598 , 9313 pmid 7588564 , 9314 pmid 7528097 , 9315 pmid 6762318 , 9316 pmid 6687683 , 9317 pmid 6606438 , 9318 pmid 6556193 , 9319 pmid 6547997 , 9320 pmid 3637050 , 9321 pmid 3492865 , 9322 pmid 3490907 , 9323 pmid 3485824 , 9324 pmid 3260956 , 9325 pmid 3257719 , 9326 pmid 3028924 , 9327 pmid 2945424 , 9328 pmid 2456771 , 9329 pmid 2435303 , 9330 pmid 2432851 , 9331 pmid 2404007 , 9332 pmid 2190106 , 9333 pmid 1618300 , 9334 pmid 1351206 , 9335 pmid 1311327 } } , 9336 { 9337 type comment , 9338 heading "Phenotypes" , 9339 version 0 , 9340 comment { 9341 { 9342 type phenotype , 9343 text "Alpha-1-antichymotrypsin deficiency" , 9344 version 0 , 9345 source { 9346 { 9347 src { 9348 db "MIM" , 9349 tag 9350 id 107280 } , 9351 anchor "MIM: 107280" } } } , 9352 { 9353 type phenotype , 9354 text "Cerebrovascular disease, occlusive" , 9355 version 0 , 9356 source { 9357 { 9358 src { 9359 db "MIM" , 9360 tag 9361 id 107280 } , 9362 anchor "MIM: 107280" } } } } } , 9363 { 9364 type comment , 9365 heading "Markers (Sequence Tagged Sites/STS)" , 9366 version 0 , 9367 comment { 9368 { 9369 type comment , 9370 version 0 , 9371 source { 9372 { 9373 src { 9374 db "UniSTS" , 9375 tag 9376 id 32177 } , 9377 anchor "RH1625" , 9378 post-text "(e-PCR)" } } , 9379 comment { 9380 { 9381 type other , 9382 label "Alternate name" , 9383 text "RH77711" , 9384 version 0 } , 9385 { 9386 type other , 9387 label "Alternate name" , 9388 text "stSG1393" , 9389 version 0 } } } , 9390 { 9391 type comment , 9392 version 0 , 9393 source { 9394 { 9395 src { 9396 db "UniSTS" , 9397 tag 9398 id 37467 } , 9399 anchor "SHGC-32982" , 9400 post-text "(e-PCR)" } } , 9401 comment { 9402 { 9403 type other , 9404 label "Alternate name" , 9405 text "EST128561" , 9406 version 0 } , 9407 { 9408 type other , 9409 label "Alternate name" , 9410 text "RH32590" , 9411 version 0 } , 9412 { 9413 type other , 9414 label "Alternate name" , 9415 text "RH53830" , 9416 version 0 } , 9417 { 9418 type other , 9419 label "Alternate name" , 9420 text "SGC32982" , 9421 version 0 } } } , 9422 { 9423 type comment , 9424 version 0 , 9425 source { 9426 { 9427 src { 9428 db "UniSTS" , 9429 tag 9430 id 64155 } , 9431 anchor "D14S845" , 9432 post-text "(e-PCR)" } } , 9433 comment { 9434 { 9435 type other , 9436 label "Alternate name" , 9437 text "GDB:588356" , 9438 version 0 } , 9439 { 9440 type other , 9441 label "Alternate name" , 9442 text "RH53900" , 9443 version 0 } , 9444 { 9445 type other , 9446 label "Alternate name" , 9447 text "UTR-04554" , 9448 version 0 } , 9449 { 9450 type other , 9451 label "Alternate name" , 9452 text "WI-7103" , 9453 version 0 } } } , 9454 { 9455 type comment , 9456 version 0 , 9457 source { 9458 { 9459 src { 9460 db "UniSTS" , 9461 tag 9462 id 66238 } , 9463 anchor "G31126" , 9464 post-text "(e-PCR)" } } , 9465 comment { 9466 { 9467 type other , 9468 label "Alternate name" , 9469 text "SHGC-19718" , 9470 version 0 } } } , 9471 { 9472 type comment , 9473 version 0 , 9474 source { 9475 { 9476 src { 9477 db "UniSTS" , 9478 tag 9479 id 74665 } , 9480 anchor "RH78280" , 9481 post-text "(e-PCR)" } } , 9482 comment { 9483 { 9484 type other , 9485 label "Alternate name" , 9486 text "stSG41027" , 9487 version 0 } } } , 9488 { 9489 type comment , 9490 version 0 , 9491 source { 9492 { 9493 src { 9494 db "UniSTS" , 9495 tag 9496 id 86678 } , 9497 anchor "RH91507" , 9498 post-text "(e-PCR)" } } , 9499 comment { 9500 { 9501 type other , 9502 label "Alternate name" , 9503 text "stSG44830" , 9504 version 0 } } } , 9505 { 9506 type comment , 9507 version 0 , 9508 source { 9509 { 9510 src { 9511 db "UniSTS" , 9512 tag 9513 id 272387 } , 9514 anchor "PMC27764P1" , 9515 post-text "(e-PCR)" } } } } } , 9516 { 9517 type comment , 9518 heading "NCBI Reference Sequences (RefSeq)" , 9519 version 0 , 9520 products { 9521 { 9522 type mRNA , 9523 heading "mRNA Sequence" , 9524 accession "NM_001085" , 9525 version 3 , 9526 source { 9527 { 9528 src { 9529 db "Nucleotide" , 9530 tag 9531 id 50659079 } , 9532 anchor "NM_001085" } } , 9533 seqs { 9534 whole 9535 gi 50659079 } , 9536 products { 9537 { 9538 type peptide , 9539 heading "Product" , 9540 accession "NP_001076" , 9541 version 2 , 9542 source { 9543 { 9544 src { 9545 db "Protein" , 9546 tag 9547 id 50659080 } , 9548 anchor "NP_001076" , 9549 post-text "serine (or cysteine) proteinase inhibitor, clade 9550 A, member 3 precursor" } } , 9551 seqs { 9552 whole 9553 gi 50659080 } , 9554 comment { 9555 { 9556 type other , 9557 heading "Conserved Domains" , 9558 version 0 , 9559 source { 9560 { 9561 src { 9562 db "PROT_CDD" , 9563 tag 9564 id 50659080 } , 9565 pre-text "(1)" , 9566 anchor "summary" } } , 9567 comment { 9568 { 9569 type other , 9570 version 0 , 9571 source { 9572 { 9573 src { 9574 db "CDD" , 9575 tag 9576 id 28234 } , 9577 anchor "cd02056: alpha-1-antitrypsin_like; 9578 alpha-1-antitrypsin_like" } } , 9579 comment { 9580 { 9581 type other , 9582 text "Location: 52 - 417 Blast Score: 1367" , 9583 version 0 } } } } } } } } , 9584 comment { 9585 { 9586 type other , 9587 heading "Source Sequence" , 9588 version 0 , 9589 source { 9590 { 9591 src { 9592 db "Nucleotide" , 9593 tag 9594 str "BC003559,BG565041" } , 9595 anchor "BC003559,BG565041" } } , 9596 comment { 9597 { 9598 type other , 9599 version 0 } } } } } } } , 9600 { 9601 type comment , 9602 heading "Related Sequences" , 9603 version 0 , 9604 products { 9605 { 9606 type genomic , 9607 heading "Genomic" , 9608 accession "X00947" , 9609 version 1 , 9610 source { 9611 { 9612 src { 9613 db "Nucleotide" , 9614 tag 9615 id 28331 } , 9616 anchor "X00947" } } , 9617 seqs { 9618 whole 9619 gi 28331 } , 9620 products { 9621 { 9622 type peptide , 9623 accession "CAA25459" , 9624 version 1 , 9625 source { 9626 { 9627 src { 9628 db "Protein" , 9629 tag 9630 id 28332 } , 9631 anchor "CAA25459" } } , 9632 seqs { 9633 whole 9634 gi 28332 } } } } , 9635 { 9636 type genomic , 9637 heading "Genomic" , 9638 accession "X68733" , 9639 version 1 , 9640 source { 9641 { 9642 src { 9643 db "Nucleotide" , 9644 tag 9645 id 439137 } , 9646 anchor "X68733" } } , 9647 seqs { 9648 whole 9649 gi 439137 } , 9650 products { 9651 { 9652 type peptide , 9653 accession "CAA48671" , 9654 version 1 , 9655 source { 9656 { 9657 src { 9658 db "Protein" , 9659 tag 9660 id 1340142 } , 9661 anchor "CAA48671" } } , 9662 seqs { 9663 whole 9664 gi 1340142 } } } } , 9665 { 9666 type mRNA , 9667 heading "mRNA" , 9668 accession "AB209060" , 9669 version 1 , 9670 source { 9671 { 9672 src { 9673 db "Nucleotide" , 9674 tag 9675 id 62087699 } , 9676 anchor "AB209060" } } , 9677 seqs { 9678 whole 9679 gi 62087699 } , 9680 products { 9681 { 9682 type peptide , 9683 accession "BAD92297" , 9684 version 1 , 9685 source { 9686 { 9687 src { 9688 db "Protein" , 9689 tag 9690 id 62087700 } , 9691 anchor "BAD92297" } } , 9692 seqs { 9693 whole 9694 gi 62087700 } } } } , 9695 { 9696 type mRNA , 9697 heading "mRNA" , 9698 accession "AF089747" , 9699 version 1 , 9700 source { 9701 { 9702 src { 9703 db "Nucleotide" , 9704 tag 9705 id 4165889 } , 9706 anchor "AF089747" } } , 9707 seqs { 9708 whole 9709 gi 4165889 } , 9710 products { 9711 { 9712 type peptide , 9713 accession "AAD08810" , 9714 version 1 , 9715 source { 9716 { 9717 src { 9718 db "Protein" , 9719 tag 9720 id 4165890 } , 9721 anchor "AAD08810" } } , 9722 seqs { 9723 whole 9724 gi 4165890 } } } } , 9725 { 9726 type mRNA , 9727 heading "mRNA" , 9728 accession "AK093049" , 9729 version 1 , 9730 source { 9731 { 9732 src { 9733 db "Nucleotide" , 9734 tag 9735 id 21751790 } , 9736 anchor "AK093049" } } , 9737 seqs { 9738 whole 9739 gi 21751790 } , 9740 products { 9741 { 9742 type peptide , 9743 text "None" , 9744 version 0 } } } , 9745 { 9746 type mRNA , 9747 heading "mRNA" , 9748 accession "AK096120" , 9749 version 1 , 9750 source { 9751 { 9752 src { 9753 db "Nucleotide" , 9754 tag 9755 id 21755531 } , 9756 anchor "AK096120" } } , 9757 seqs { 9758 whole 9759 gi 21755531 } , 9760 products { 9761 { 9762 type peptide , 9763 text "None" , 9764 version 0 } } } , 9765 { 9766 type mRNA , 9767 heading "mRNA" , 9768 accession "AK123091" , 9769 version 1 , 9770 source { 9771 { 9772 src { 9773 db "Nucleotide" , 9774 tag 9775 id 34528556 } , 9776 anchor "AK123091" } } , 9777 seqs { 9778 whole 9779 gi 34528556 } , 9780 products { 9781 { 9782 type peptide , 9783 text "None" , 9784 version 0 } } } , 9785 { 9786 type mRNA , 9787 heading "mRNA" , 9788 accession "BC003559" , 9789 version 1 , 9790 source { 9791 { 9792 src { 9793 db "Nucleotide" , 9794 tag 9795 id 13097704 } , 9796 anchor "BC003559" } } , 9797 seqs { 9798 whole 9799 gi 13097704 } , 9800 products { 9801 { 9802 type peptide , 9803 accession "AAH03559" , 9804 version 1 , 9805 source { 9806 { 9807 src { 9808 db "Protein" , 9809 tag 9810 id 13097705 } , 9811 anchor "AAH03559" } } , 9812 seqs { 9813 whole 9814 gi 13097705 } } } } , 9815 { 9816 type mRNA , 9817 heading "mRNA" , 9818 accession "BC010530" , 9819 version 1 , 9820 source { 9821 { 9822 src { 9823 db "Nucleotide" , 9824 tag 9825 id 14714765 } , 9826 anchor "BC010530" } } , 9827 seqs { 9828 whole 9829 gi 14714765 } , 9830 products { 9831 { 9832 type peptide , 9833 accession "AAH10530" , 9834 version 1 , 9835 source { 9836 { 9837 src { 9838 db "Protein" , 9839 tag 9840 id 14714766 } , 9841 anchor "AAH10530" } } , 9842 seqs { 9843 whole 9844 gi 14714766 } } } } , 9845 { 9846 type mRNA , 9847 heading "mRNA" , 9848 accession "BC013189" , 9849 version 1 , 9850 source { 9851 { 9852 src { 9853 db "Nucleotide" , 9854 tag 9855 id 15341984 } , 9856 anchor "BC013189" } } , 9857 seqs { 9858 whole 9859 gi 15341984 } , 9860 products { 9861 { 9862 type peptide , 9863 accession "AAH13189" , 9864 version 1 , 9865 source { 9866 { 9867 src { 9868 db "Protein" , 9869 tag 9870 id 15341985 } , 9871 anchor "AAH13189" } } , 9872 seqs { 9873 whole 9874 gi 15341985 } } } } , 9875 { 9876 type mRNA , 9877 heading "mRNA" , 9878 accession "BC034554" , 9879 version 1 , 9880 source { 9881 { 9882 src { 9883 db "Nucleotide" , 9884 tag 9885 id 21961492 } , 9886 anchor "BC034554" } } , 9887 seqs { 9888 whole 9889 gi 21961492 } , 9890 products { 9891 { 9892 type peptide , 9893 accession "AAH34554" , 9894 version 1 , 9895 source { 9896 { 9897 src { 9898 db "Protein" , 9899 tag 9900 id 21961493 } , 9901 anchor "AAH34554" } } , 9902 seqs { 9903 whole 9904 gi 21961493 } } } } , 9905 { 9906 type mRNA , 9907 heading "mRNA" , 9908 accession "BC070265" , 9909 version 1 , 9910 source { 9911 { 9912 src { 9913 db "Nucleotide" , 9914 tag 9915 id 47124537 } , 9916 anchor "BC070265" } } , 9917 seqs { 9918 whole 9919 gi 47124537 } , 9920 products { 9921 { 9922 type peptide , 9923 accession "AAH70265" , 9924 version 1 , 9925 source { 9926 { 9927 src { 9928 db "Protein" , 9929 tag 9930 id 47124538 } , 9931 anchor "AAH70265" } } , 9932 seqs { 9933 whole 9934 gi 47124538 } } } } , 9935 { 9936 type mRNA , 9937 heading "mRNA" , 9938 accession "BG565041" , 9939 version 1 , 9940 source { 9941 { 9942 src { 9943 db "Nucleotide" , 9944 tag 9945 id 13572694 } , 9946 anchor "BG565041" } } , 9947 seqs { 9948 whole 9949 gi 13572694 } , 9950 products { 9951 { 9952 type peptide , 9953 text "None" , 9954 version 0 } } } , 9955 { 9956 type mRNA , 9957 heading "mRNA" , 9958 accession "J05176" , 9959 version 1 , 9960 source { 9961 { 9962 src { 9963 db "Nucleotide" , 9964 tag 9965 id 177932 } , 9966 anchor "J05176" } } , 9967 seqs { 9968 whole 9969 gi 177932 } , 9970 products { 9971 { 9972 type peptide , 9973 accession "AAA51560" , 9974 version 1 , 9975 source { 9976 { 9977 src { 9978 db "Protein" , 9979 tag 9980 id 177933 } , 9981 anchor "AAA51560" } } , 9982 seqs { 9983 whole 9984 gi 177933 } } } } , 9985 { 9986 type mRNA , 9987 heading "mRNA" , 9988 accession "K01500" , 9989 version 1 , 9990 source { 9991 { 9992 src { 9993 db "Nucleotide" , 9994 tag 9995 id 177808 } , 9996 anchor "K01500" } } , 9997 seqs { 9998 whole 9999 gi 177808 } , 10000 products { 10001 { 10002 type peptide , 10003 accession "AAA51543" , 10004 version 1 , 10005 source { 10006 { 10007 src { 10008 db "Protein" , 10009 tag 10010 id 177809 } , 10011 anchor "AAA51543" } } , 10012 seqs { 10013 whole 10014 gi 177809 } } } } , 10015 { 10016 type mRNA , 10017 heading "mRNA" , 10018 accession "M18906" , 10019 version 1 , 10020 source { 10021 { 10022 src { 10023 db "Nucleotide" , 10024 tag 10025 id 177928 } , 10026 anchor "M18906" } } , 10027 seqs { 10028 whole 10029 gi 177928 } , 10030 products { 10031 { 10032 type peptide , 10033 accession "AAA51559" , 10034 version 1 , 10035 source { 10036 { 10037 src { 10038 db "Protein" , 10039 tag 10040 id 177931 } , 10041 anchor "AAA51559" } } , 10042 seqs { 10043 whole 10044 gi 177931 } } } } , 10045 { 10046 type other , 10047 text "None" , 10048 version 0 , 10049 products { 10050 { 10051 type peptide , 10052 accession "P01011" , 10053 version 0 , 10054 source { 10055 { 10056 src { 10057 db "Protein" , 10058 tag 10059 id 112874 } , 10060 anchor "P01011" } } , 10061 seqs { 10062 whole 10063 gi 112874 } } } } } } , 10064 { 10065 type comment , 10066 heading "Additional Links" , 10067 version 0 , 10068 comment { 10069 { 10070 type comment , 10071 version 0 , 10072 source { 10073 { 10074 src { 10075 db "Evidence Viewer" , 10076 tag 10077 str "12" } , 10078 anchor "Evidence Viewer" , 10079 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 10080g=NT_026437.11&gene=SERPINA3&lid=12&from=76080524&to=76090144" } } } , 10081 { 10082 type comment , 10083 version 0 , 10084 source { 10085 { 10086 src { 10087 db "ModelMaker" , 10088 tag 10089 str "12" } , 10090 anchor "ModelMaker" , 10091 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 1009206&contig=NT_026437.11&gene=SERPINA3&lid=12" } } } , 10093 { 10094 type comment , 10095 text "UniGene" , 10096 version 0 , 10097 xtra-properties { 10098 { 10099 tag "UNIGENE" , 10100 value "Hs.534293" } } , 10101 source { 10102 { 10103 src { 10104 db "UniGene" , 10105 tag 10106 str "Hs.534293" } , 10107 anchor "Hs.534293" , 10108 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=53 101094293" } } } , 10110 { 10111 type comment , 10112 text "MIM" , 10113 version 0 , 10114 source { 10115 { 10116 src { 10117 db "MIM" , 10118 tag 10119 str "107280" } , 10120 anchor "107280" } } } , 10121 { 10122 type comment , 10123 version 0 , 10124 source { 10125 { 10126 src { 10127 db "HomoloGene" , 10128 tag 10129 str "12" } , 10130 anchor "HomoloGene" , 10131 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 1013212[loc]&TAXID=9606" } } } , 10133 { 10134 type comment , 10135 version 0 , 10136 source { 10137 { 10138 src { 10139 db "AceView" , 10140 tag 10141 id 12 } , 10142 anchor "AceView" , 10143 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 10144ocusid&org=9606&l=12" } } } , 10145 { 10146 type comment , 10147 version 0 , 10148 source { 10149 { 10150 src { 10151 db "GDB" , 10152 tag 10153 str "GDB:118955" } } } } , 10154 { 10155 type comment , 10156 version 0 , 10157 source { 10158 { 10159 src { 10160 db "Ensembl" , 10161 tag 10162 str "" } , 10163 url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=AK093 10164049" } } } , 10165 { 10166 type comment , 10167 version 0 , 10168 source { 10169 { 10170 src { 10171 db "UCSC" , 10172 tag 10173 str "" } , 10174 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position= 10175AK093049" } } } , 10176 { 10177 type comment , 10178 version 0 , 10179 source { 10180 { 10181 src { 10182 db "KEGG" , 10183 tag 10184 str "" } , 10185 url "http://www.genome.ad.jp/dbget-bin/www_bget?hsa:12" } } } , 10186 { 10187 type comment , 10188 version 0 , 10189 source { 10190 { 10191 src { 10192 db "MGC" , 10193 tag 10194 str "BC003559,BC010530,BC034554" } , 10195 anchor "MGC" , 10196 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC003559 10197,BC010530,BC034554" } } } } } , 10198 { 10199 type comment , 10200 heading "Pathways" , 10201 version 0 , 10202 comment { 10203 { 10204 type comment , 10205 text "KEGG pathway: Alzheimer's disease" , 10206 version 0 , 10207 source { 10208 { 10209 src { 10210 db "05010" , 10211 tag 10212 str "05010" } , 10213 anchor "05010" , 10214 url "http://www.genome.jp/dbget-bin/show_pathway?hsa05010+12" } } } } } , 10215 { 10216 type generif , 10217 text "overexpression of ACT by astrocytes could thus contribute to 10218 increased beta-amyloid fibril formation in Alzheimer's disease" , 10219 version 0 , 10220 refs { 10221 pmid 15530656 } , 10222 create-date 10223 str "Jan 29 2005 10:01AM" , 10224 update-date 10225 str "Jan 29 2005 1:54PM" } , 10226 { 10227 type generif , 10228 text "Multivariate analysis showed that ACT mRNA level, but not STC2 10229 mRNA level, in HR-positive patients, was a significant prognostic factor (P = 10230 0.042), which was independent of tumor size and lymph node metastases." , 10231 version 0 , 10232 refs { 10233 pmid 15546506 } , 10234 create-date 10235 str "Jan 15 2005 10:01AM" , 10236 update-date 10237 str "Jan 15 2005 4:35PM" } , 10238 { 10239 type generif , 10240 text "Alpha1-antichymotrypsin-AA may confer a modest protection against 10241 developing early-onset Parkinson disease in women" , 10242 version 0 , 10243 refs { 10244 pmid 15542006 } , 10245 create-date 10246 str "Jan 15 2005 10:01AM" , 10247 update-date 10248 str "Jan 15 2005 1:01PM" } , 10249 { 10250 type generif , 10251 text "Polymeric AACT specifically seeds the polymerization of native 10252 protein by a serpin-dependent process that occurs under physiological 10253 conditions and may be important in the deposition of AACT in plaques in 10254 patients with Alzheimer's disease." , 10255 version 0 , 10256 refs { 10257 pmid 12600202 } , 10258 create-date 10259 str "May 26 2003 12:00AM" , 10260 update-date 10261 str "Jun 1 2003 7:01AM" } , 10262 { 10263 type generif , 10264 text "alpha(1)-antichymotrypsin polymorphism: a risk factor for 10265 hemorrhagic stroke in normotensive subjects." , 10266 version 0 , 10267 refs { 10268 pmid 11692021 } , 10269 create-date 10270 str "Mar 5 2003 12:00AM" , 10271 update-date 10272 str "Mar 23 2003 7:01AM" } , 10273 { 10274 type generif , 10275 text "alpha(1)-antitrypsin and antichymotrypsin are produced by the 10276 mammary gland and are present in milk in relatively high amounts in early 10277 lactation" , 10278 version 0 , 10279 refs { 10280 pmid 12324297 } , 10281 create-date 10282 str "Oct 11 2002 12:00AM" , 10283 update-date 10284 str "Feb 2 2003 7:01AM" } , 10285 { 10286 type generif , 10287 text "Gene regulation of the serine proteinase inhibitors 10288 alpha1-antitrypsin and alpha1-antichymotrypsin." , 10289 version 0 , 10290 refs { 10291 pmid 12023832 } , 10292 create-date 10293 str "Oct 9 2002 12:00AM" , 10294 update-date 10295 str "Feb 2 2003 7:01AM" } , 10296 { 10297 type generif , 10298 text "data suggested that the ApoE epsilon2/epsilon4 genotype might be a 10299 susceptibility variant of moderate effect for sporadic idiopathic Parkinson 10300 disease in our samples, whereas the ACT gene signal peptide polymorphism 10301 might not" , 10302 version 0 , 10303 refs { 10304 pmid 11992569 } , 10305 create-date 10306 str "Sep 26 2002 12:00AM" , 10307 update-date 10308 str "Oct 7 2002 8:10AM" } , 10309 { 10310 type generif , 10311 text "no association seen between alpha 1-antichymotrypsin and time to 10312 psychosis in Alzheimer's disease" , 10313 version 0 , 10314 refs { 10315 pmid 11936240 } , 10316 create-date 10317 str "Aug 28 2002 12:00AM" , 10318 update-date 10319 str "Sep 16 2002 5:48AM" } , 10320 { 10321 type generif , 10322 text "significantly higher in plasma of Alzheimer patients compared to 10323 controls" , 10324 version 0 , 10325 refs { 10326 pmid 11959399 } , 10327 create-date 10328 str "Jul 22 2002 12:00AM" , 10329 update-date 10330 str "Jul 29 2002 6:27PM" } , 10331 { 10332 type generif , 10333 text "A25G and G39A substitutions in the AACT gene are probably one of 10334 the risk factors to Alzheimer's disease (AD) in Han Chinese." , 10335 version 0 , 10336 refs { 10337 pmid 11798857 } , 10338 create-date 10339 str "Apr 7 2002 12:00AM" , 10340 update-date 10341 str "Apr 13 2002 5:25PM" } , 10342 { 10343 type generif , 10344 heading "Interactions" , 10345 version 0 , 10346 comment { 10347 { 10348 type generif , 10349 text "Alpha-1 ACT interacts with and inhibits cathepsin G." , 10350 version 0 , 10351 refs { 10352 pmid 15131125 } , 10353 source { 10354 { 10355 src { 10356 db "BIND" , 10357 tag 10358 id 149291 } , 10359 anchor "BIND" } } , 10360 comment { 10361 { 10362 type comment , 10363 label "SERPINA3" , 10364 accession "NP_001076" , 10365 version 1 } , 10366 { 10367 type comment , 10368 label "CTSG" , 10369 accession "NP_001902" , 10370 version 1 , 10371 source { 10372 { 10373 src { 10374 db "GeneID" , 10375 tag 10376 id 1511 } } } } } , 10377 create-date 10378 str "2005-01-21 20:10 EDT" , 10379 update-date 10380 str "2005-01-21 20:19 EDT" } , 10381 { 10382 type generif , 10383 text "LRP interacts with alpha-1-ACT." , 10384 version 0 , 10385 refs { 10386 pmid 15131125 } , 10387 source { 10388 { 10389 src { 10390 db "BIND" , 10391 tag 10392 id 149296 } , 10393 anchor "BIND" } } , 10394 comment { 10395 { 10396 type comment , 10397 label "SERPINA3" , 10398 accession "NP_001076" , 10399 version 1 } , 10400 { 10401 type comment , 10402 label "LRP1" , 10403 accession "NP_002323" , 10404 version 1 , 10405 source { 10406 { 10407 src { 10408 db "GeneID" , 10409 tag 10410 id 4035 } } } } } , 10411 create-date 10412 str "2005-01-21 20:10 EDT" , 10413 update-date 10414 str "2005-01-21 20:19 EDT" } } } } , 10415 unique-keys { 10416 { 10417 db "LocusID" , 10418 tag 10419 id 12 } , 10420 { 10421 db "MIM" , 10422 tag 10423 id 107280 } } , 10424 xtra-index-terms { 10425 "LOC12" } , 10426 xtra-properties { 10427 { 10428 tag "PROP" , 10429 value "phenotype" } } } 10430Entrezgene ::= { 10431 track-info { 10432 geneid 13 , 10433 status live , 10434 create-date 10435 std { 10436 year 2003 , 10437 month 8 , 10438 day 28 , 10439 hour 20 , 10440 minute 30 , 10441 second 0 } , 10442 update-date 10443 std { 10444 year 2005 , 10445 month 3 , 10446 day 5 , 10447 hour 11 , 10448 minute 30 , 10449 second 0 } } , 10450 type protein-coding , 10451 source { 10452 genome genomic , 10453 origin natural , 10454 org { 10455 taxname "Homo sapiens" , 10456 common "human" , 10457 db { 10458 { 10459 db "taxon" , 10460 tag 10461 id 9606 } } , 10462 syn { 10463 "man" } , 10464 orgname { 10465 name 10466 binomial { 10467 genus "Homo" , 10468 species "sapiens" } , 10469 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 10470 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 10471 Hominidae; Homo" , 10472 gcode 1 , 10473 mgcode 2 , 10474 div "PRI" } } , 10475 subtype { 10476 { 10477 subtype chromosome , 10478 name "3" } } } , 10479 gene { 10480 locus "AADAC" , 10481 desc "arylacetamide deacetylase (esterase)" , 10482 maploc "3q21.3-q25.2" , 10483 db { 10484 { 10485 db "MIM" , 10486 tag 10487 id 600338 } } , 10488 syn { 10489 "DAC" } , 10490 locus-tag "HGNC:17" } , 10491 prot { 10492 name { 10493 "arylacetamide deacetylase" } } , 10494 summary "Microsomal arylacetamide deacetylase competes against the activity 10495 of cytosolic arylamine N-acetyltransferase, which catalyzes one of the 10496 initial biotransformation pathways for arylamine and heterocyclic amine 10497 carcinogens" , 10498 location { 10499 { 10500 display-str "3q21.3-q25.2" , 10501 method 10502 map-type cyto } } , 10503 gene-source { 10504 src "LocusLink" , 10505 src-int 13 , 10506 src-str2 "13" , 10507 gene-display FALSE , 10508 locus-display FALSE , 10509 extra-terms FALSE } , 10510 locus { 10511 { 10512 type genomic , 10513 heading "Reference" , 10514 accession "NC_000003" , 10515 version 9 , 10516 seqs { 10517 int { 10518 from 153014563 , 10519 to 153028971 , 10520 strand plus , 10521 id 10522 gi 51511463 } } , 10523 products { 10524 { 10525 type mRNA , 10526 heading "Reference" , 10527 accession "NM_001086" , 10528 version 1 , 10529 genomic-coords { 10530 mix { 10531 int { 10532 from 153014563 , 10533 to 153014785 , 10534 strand plus , 10535 id 10536 gi 51511463 } , 10537 int { 10538 from 153017851 , 10539 to 153018073 , 10540 strand plus , 10541 id 10542 gi 51511463 } , 10543 int { 10544 from 153020868 , 10545 to 153020937 , 10546 strand plus , 10547 id 10548 gi 51511463 } , 10549 int { 10550 from 153025148 , 10551 to 153025319 , 10552 strand plus , 10553 id 10554 gi 51511463 } , 10555 int { 10556 from 153028061 , 10557 to 153028971 , 10558 strand plus , 10559 id 10560 gi 51511463 } } } , 10561 seqs { 10562 whole 10563 gi 4557226 } , 10564 products { 10565 { 10566 type peptide , 10567 heading "Reference" , 10568 accession "NP_001077" , 10569 version 1 , 10570 genomic-coords { 10571 packed-int { 10572 { 10573 from 153014648 , 10574 to 153014785 , 10575 strand plus , 10576 id 10577 gi 51511463 } , 10578 { 10579 from 153017851 , 10580 to 153018073 , 10581 strand plus , 10582 id 10583 gi 51511463 } , 10584 { 10585 from 153020868 , 10586 to 153020937 , 10587 strand plus , 10588 id 10589 gi 51511463 } , 10590 { 10591 from 153025148 , 10592 to 153025319 , 10593 strand plus , 10594 id 10595 gi 51511463 } , 10596 { 10597 from 153028061 , 10598 to 153028657 , 10599 strand plus , 10600 id 10601 gi 51511463 } } } , 10602 seqs { 10603 whole 10604 gi 4557227 } , 10605 comment { 10606 { 10607 type property , 10608 label "EC" , 10609 text "3.1.1.-" , 10610 version 0 , 10611 xtra-properties { 10612 { 10613 tag "EC" , 10614 value "3.1.1.-" } } } } } } } } } , 10615 { 10616 type genomic , 10617 heading "Reference" , 10618 accession "NT_005612" , 10619 version 14 , 10620 seqs { 10621 int { 10622 from 58027019 , 10623 to 58041427 , 10624 strand plus , 10625 id 10626 gi 37550867 } } , 10627 products { 10628 { 10629 type mRNA , 10630 heading "Reference" , 10631 accession "NM_001086" , 10632 version 1 , 10633 genomic-coords { 10634 mix { 10635 int { 10636 from 58027019 , 10637 to 58027241 , 10638 strand plus , 10639 id 10640 gi 37550867 } , 10641 int { 10642 from 58030307 , 10643 to 58030529 , 10644 strand plus , 10645 id 10646 gi 37550867 } , 10647 int { 10648 from 58033324 , 10649 to 58033393 , 10650 strand plus , 10651 id 10652 gi 37550867 } , 10653 int { 10654 from 58037604 , 10655 to 58037775 , 10656 strand plus , 10657 id 10658 gi 37550867 } , 10659 int { 10660 from 58040517 , 10661 to 58041427 , 10662 strand plus , 10663 id 10664 gi 37550867 } } } , 10665 seqs { 10666 whole 10667 gi 4557226 } , 10668 products { 10669 { 10670 type peptide , 10671 heading "Reference" , 10672 accession "NP_001077" , 10673 version 1 , 10674 genomic-coords { 10675 packed-int { 10676 { 10677 from 58027104 , 10678 to 58027241 , 10679 strand plus , 10680 id 10681 gi 37550867 } , 10682 { 10683 from 58030307 , 10684 to 58030529 , 10685 strand plus , 10686 id 10687 gi 37550867 } , 10688 { 10689 from 58033324 , 10690 to 58033393 , 10691 strand plus , 10692 id 10693 gi 37550867 } , 10694 { 10695 from 58037604 , 10696 to 58037775 , 10697 strand plus , 10698 id 10699 gi 37550867 } , 10700 { 10701 from 58040517 , 10702 to 58041113 , 10703 strand plus , 10704 id 10705 gi 37550867 } } } , 10706 seqs { 10707 whole 10708 gi 4557227 } , 10709 comment { 10710 { 10711 type property , 10712 label "EC" , 10713 text "3.1.1.-" , 10714 version 0 , 10715 xtra-properties { 10716 { 10717 tag "EC" , 10718 value "3.1.1.-" } } } } } } } } } , 10719 { 10720 type genomic , 10721 heading "Reference" , 10722 accession "NT_086641" , 10723 version 1 , 10724 seqs { 10725 int { 10726 from 24339789 , 10727 to 24354221 , 10728 strand plus , 10729 id 10730 gi 51464125 } } , 10731 products { 10732 { 10733 type mRNA , 10734 heading "Reference" , 10735 accession "NM_001086" , 10736 version 1 , 10737 genomic-coords { 10738 mix { 10739 int { 10740 from 24339789 , 10741 to 24340011 , 10742 strand plus , 10743 id 10744 gi 51464125 } , 10745 int { 10746 from 24343078 , 10747 to 24343300 , 10748 strand plus , 10749 id 10750 gi 51464125 } , 10751 int { 10752 from 24346094 , 10753 to 24346163 , 10754 strand plus , 10755 id 10756 gi 51464125 } , 10757 int { 10758 from 24350369 , 10759 to 24350540 , 10760 strand plus , 10761 id 10762 gi 51464125 } , 10763 int { 10764 from 24353311 , 10765 to 24354221 , 10766 strand plus , 10767 id 10768 gi 51464125 } } } , 10769 seqs { 10770 whole 10771 gi 4557226 } , 10772 products { 10773 { 10774 type peptide , 10775 heading "Reference" , 10776 accession "NP_001077" , 10777 version 1 , 10778 genomic-coords { 10779 packed-int { 10780 { 10781 from 24339874 , 10782 to 24340011 , 10783 strand plus , 10784 id 10785 gi 51464125 } , 10786 { 10787 from 24343078 , 10788 to 24343300 , 10789 strand plus , 10790 id 10791 gi 51464125 } , 10792 { 10793 from 24346094 , 10794 to 24346163 , 10795 strand plus , 10796 id 10797 gi 51464125 } , 10798 { 10799 from 24350369 , 10800 to 24350540 , 10801 strand plus , 10802 id 10803 gi 51464125 } , 10804 { 10805 from 24353311 , 10806 to 24353907 , 10807 strand plus , 10808 id 10809 gi 51464125 } } } , 10810 seqs { 10811 whole 10812 gi 4557227 } , 10813 comment { 10814 { 10815 type property , 10816 label "EC" , 10817 text "3.1.1.-" , 10818 version 0 , 10819 xtra-properties { 10820 { 10821 tag "EC" , 10822 value "3.1.1.-" } } } } } } } } } } , 10823 properties { 10824 { 10825 type comment , 10826 label "Nomenclature" , 10827 version 0 , 10828 source { 10829 { 10830 anchor "HUGO Gene Nomenclature Committee" } } , 10831 properties { 10832 { 10833 type property , 10834 label "Official Symbol" , 10835 text "AADAC" , 10836 version 0 } , 10837 { 10838 type property , 10839 label "Official Full Name" , 10840 text "arylacetamide deacetylase (esterase)" , 10841 version 0 } } } , 10842 { 10843 type comment , 10844 heading "GeneOntology" , 10845 version 0 , 10846 source { 10847 { 10848 pre-text "Provided by" , 10849 anchor "GOA" , 10850 url "http://www.ebi.ac.uk/GOA/" } } , 10851 comment { 10852 { 10853 type comment , 10854 label "Function" , 10855 version 0 , 10856 comment { 10857 { 10858 type comment , 10859 version 0 , 10860 refs { 10861 pmid 9665742 } , 10862 source { 10863 { 10864 src { 10865 db "GO" , 10866 tag 10867 id 19213 } , 10868 anchor "deacetylase activity" , 10869 post-text "evidence: IDA" } } } } } , 10870 { 10871 type comment , 10872 label "Process" , 10873 version 0 , 10874 comment { 10875 { 10876 type comment , 10877 version 0 , 10878 source { 10879 { 10880 src { 10881 db "GO" , 10882 tag 10883 id 8152 } , 10884 anchor "metabolism" , 10885 post-text "evidence: IEA" } } } } } , 10886 { 10887 type comment , 10888 label "Component" , 10889 version 0 , 10890 comment { 10891 { 10892 type comment , 10893 version 0 , 10894 refs { 10895 pmid 10318829 , 10896 pmid 15152005 } , 10897 source { 10898 { 10899 src { 10900 db "GO" , 10901 tag 10902 id 5789 } , 10903 anchor "endoplasmic reticulum membrane" , 10904 post-text "evidence: IDA" } } } , 10905 { 10906 type comment , 10907 version 0 , 10908 source { 10909 { 10910 src { 10911 db "GO" , 10912 tag 10913 id 16021 } , 10914 anchor "integral to membrane" , 10915 post-text "evidence: IEA" } } } , 10916 { 10917 type comment , 10918 version 0 , 10919 refs { 10920 pmid 8063807 } , 10921 source { 10922 { 10923 src { 10924 db "GO" , 10925 tag 10926 id 5792 } , 10927 anchor "microsome" , 10928 post-text "evidence: TAS" } } } } } } } } , 10929 homology { 10930 { 10931 type comment , 10932 heading "Mouse, Rat" , 10933 version 0 , 10934 source { 10935 { 10936 src { 10937 db "HomoloGene" , 10938 tag 10939 id 37436 } , 10940 anchor "Map Viewer" , 10941 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=3&M 10942APS=genes-r-org/rat-chr/human%3A3,genes-r-org/mouse-chr/human%3A3,genes-r-org/ 10943human-chr3&query=e%3A13[id]+AND+gene[obj_type]&QSTR=aadac&cmd=focus&fill=10" } } } } , 10944 comments { 10945 { 10946 type comment , 10947 heading "LocusTagLink" , 10948 version 0 , 10949 source { 10950 { 10951 src { 10952 db "HGNC" , 10953 tag 10954 id 17 } } } } , 10955 { 10956 type comment , 10957 heading "RefSeq Status" , 10958 label "REVIEWED" , 10959 version 0 } , 10960 { 10961 type comment , 10962 version 0 , 10963 refs { 10964 pmid 15152005 , 10965 pmid 12721789 , 10966 pmid 12477932 , 10967 pmid 10318829 , 10968 pmid 9665742 , 10969 pmid 9299245 , 10970 pmid 8063807 } } , 10971 { 10972 type comment , 10973 heading "Markers (Sequence Tagged Sites/STS)" , 10974 version 0 , 10975 comment { 10976 { 10977 type comment , 10978 version 0 , 10979 source { 10980 { 10981 src { 10982 db "UniSTS" , 10983 tag 10984 id 13170 } , 10985 anchor "STS-L32179" , 10986 post-text "(e-PCR)" } } , 10987 comment { 10988 { 10989 type other , 10990 label "Alternate name" , 10991 text "RH41545" , 10992 version 0 } , 10993 { 10994 type other , 10995 label "Alternate name" , 10996 text "sts-L32179" , 10997 version 0 } } } , 10998 { 10999 type comment , 11000 version 0 , 11001 source { 11002 { 11003 src { 11004 db "UniSTS" , 11005 tag 11006 id 18863 } , 11007 anchor "D3S4189" , 11008 post-text "(e-PCR)" } } , 11009 comment { 11010 { 11011 type other , 11012 label "Alternate name" , 11013 text "SHGC-9733" , 11014 version 0 } } } , 11015 { 11016 type comment , 11017 version 0 , 11018 source { 11019 { 11020 src { 11021 db "UniSTS" , 11022 tag 11023 id 24707 } , 11024 anchor "RH36344" , 11025 post-text "(e-PCR)" } } , 11026 comment { 11027 { 11028 type other , 11029 label "Alternate name" , 11030 text "stSG13141" , 11031 version 0 } } } , 11032 { 11033 type comment , 11034 version 0 , 11035 source { 11036 { 11037 src { 11038 db "UniSTS" , 11039 tag 11040 id 136046 } , 11041 anchor "RH124029" , 11042 post-text "(e-PCR)" } } , 11043 comment { 11044 { 11045 type other , 11046 label "Alternate name" , 11047 text "SHGC-105511" , 11048 version 0 } } } } } , 11049 { 11050 type comment , 11051 heading "NCBI Reference Sequences (RefSeq)" , 11052 version 0 , 11053 products { 11054 { 11055 type mRNA , 11056 heading "mRNA Sequence" , 11057 accession "NM_001086" , 11058 version 1 , 11059 source { 11060 { 11061 src { 11062 db "Nucleotide" , 11063 tag 11064 id 4557226 } , 11065 anchor "NM_001086" } } , 11066 seqs { 11067 whole 11068 gi 4557226 } , 11069 products { 11070 { 11071 type peptide , 11072 heading "Product" , 11073 accession "NP_001077" , 11074 version 1 , 11075 source { 11076 { 11077 src { 11078 db "Protein" , 11079 tag 11080 id 4557227 } , 11081 anchor "NP_001077" , 11082 post-text "arylacetamide deacetylase" } } , 11083 seqs { 11084 whole 11085 gi 4557227 } , 11086 comment { 11087 { 11088 type other , 11089 heading "Conserved Domains" , 11090 version 0 , 11091 source { 11092 { 11093 src { 11094 db "PROT_CDD" , 11095 tag 11096 id 4557227 } , 11097 pre-text "(2)" , 11098 anchor "summary" } } , 11099 comment { 11100 { 11101 type other , 11102 version 0 , 11103 source { 11104 { 11105 src { 11106 db "CDD" , 11107 tag 11108 id 10527 } , 11109 anchor "COG0657: Aes; Esterase/lipase [Lipid 11110 metabolism]" } } , 11111 comment { 11112 { 11113 type other , 11114 text "Location: 33 - 399 Blast Score: 380" , 11115 version 0 } } } , 11116 { 11117 type other , 11118 version 0 , 11119 source { 11120 { 11121 src { 11122 db "CDD" , 11123 tag 11124 id 16555 } , 11125 anchor "cd00312: Esterase_lipase; Esterases and 11126 lipases (includes fungal lipases, cholinesterases, etc" } } , 11127 comment { 11128 { 11129 type other , 11130 text "Location: 91 - 203 Blast Score: 144" , 11131 version 0 } } } } } } } } , 11132 comment { 11133 { 11134 type other , 11135 heading "Source Sequence" , 11136 version 0 , 11137 source { 11138 { 11139 src { 11140 db "Nucleotide" , 11141 tag 11142 str "L32179" } , 11143 anchor "L32179" } } , 11144 comment { 11145 { 11146 type other , 11147 version 0 } } } } } } } , 11148 { 11149 type comment , 11150 heading "Related Sequences" , 11151 version 0 , 11152 products { 11153 { 11154 type mRNA , 11155 heading "mRNA" , 11156 accession "BC020706" , 11157 version 1 , 11158 source { 11159 { 11160 src { 11161 db "Nucleotide" , 11162 tag 11163 id 18088402 } , 11164 anchor "BC020706" } } , 11165 seqs { 11166 whole 11167 gi 18088402 } , 11168 products { 11169 { 11170 type peptide , 11171 text "None" , 11172 version 0 } } } , 11173 { 11174 type mRNA , 11175 heading "mRNA" , 11176 accession "BC032309" , 11177 version 1 , 11178 source { 11179 { 11180 src { 11181 db "Nucleotide" , 11182 tag 11183 id 21595550 } , 11184 anchor "BC032309" } } , 11185 seqs { 11186 whole 11187 gi 21595550 } , 11188 products { 11189 { 11190 type peptide , 11191 accession "AAH32309" , 11192 version 1 , 11193 source { 11194 { 11195 src { 11196 db "Protein" , 11197 tag 11198 id 21595551 } , 11199 anchor "AAH32309" } } , 11200 seqs { 11201 whole 11202 gi 21595551 } } } } , 11203 { 11204 type mRNA , 11205 heading "mRNA" , 11206 accession "L32179" , 11207 version 1 , 11208 source { 11209 { 11210 src { 11211 db "Nucleotide" , 11212 tag 11213 id 537513 } , 11214 anchor "L32179" } } , 11215 seqs { 11216 whole 11217 gi 537513 } , 11218 products { 11219 { 11220 type peptide , 11221 accession "AAA35551" , 11222 version 1 , 11223 source { 11224 { 11225 src { 11226 db "Protein" , 11227 tag 11228 id 537514 } , 11229 anchor "AAA35551" } } , 11230 seqs { 11231 whole 11232 gi 537514 } } } } , 11233 { 11234 type other , 11235 text "None" , 11236 version 0 , 11237 products { 11238 { 11239 type peptide , 11240 accession "P22760" , 11241 version 0 , 11242 source { 11243 { 11244 src { 11245 db "Protein" , 11246 tag 11247 id 57015294 } , 11248 anchor "P22760" } } , 11249 seqs { 11250 whole 11251 gi 57015294 } } } } } } , 11252 { 11253 type comment , 11254 heading "Additional Links" , 11255 version 0 , 11256 comment { 11257 { 11258 type comment , 11259 version 0 , 11260 source { 11261 { 11262 src { 11263 db "Evidence Viewer" , 11264 tag 11265 str "13" } , 11266 anchor "Evidence Viewer" , 11267 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 11268g=NT_005612.14&gene=AADAC&lid=13&from=58027020&to=58041428" } } } , 11269 { 11270 type comment , 11271 version 0 , 11272 source { 11273 { 11274 src { 11275 db "ModelMaker" , 11276 tag 11277 str "13" } , 11278 anchor "ModelMaker" , 11279 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 1128006&contig=NT_005612.14&gene=AADAC&lid=13" } } } , 11281 { 11282 type comment , 11283 text "UniGene" , 11284 version 0 , 11285 xtra-properties { 11286 { 11287 tag "UNIGENE" , 11288 value "Hs.506908" } } , 11289 source { 11290 { 11291 src { 11292 db "UniGene" , 11293 tag 11294 str "Hs.506908" } , 11295 anchor "Hs.506908" , 11296 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=50 112976908" } } } , 11298 { 11299 type comment , 11300 text "MIM" , 11301 version 0 , 11302 source { 11303 { 11304 src { 11305 db "MIM" , 11306 tag 11307 str "600338" } , 11308 anchor "600338" } } } , 11309 { 11310 type comment , 11311 version 0 , 11312 source { 11313 { 11314 src { 11315 db "HomoloGene" , 11316 tag 11317 str "13" } , 11318 anchor "HomoloGene" , 11319 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 1132013[loc]&TAXID=9606" } } } , 11321 { 11322 type comment , 11323 version 0 , 11324 source { 11325 { 11326 src { 11327 db "AceView" , 11328 tag 11329 id 13 } , 11330 anchor "AceView" , 11331 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 11332ocusid&org=9606&l=13" } } } , 11333 { 11334 type comment , 11335 version 0 , 11336 source { 11337 { 11338 src { 11339 db "GDB" , 11340 tag 11341 str "GDB:392587" } } } } , 11342 { 11343 type comment , 11344 version 0 , 11345 source { 11346 { 11347 src { 11348 db "Ensembl" , 11349 tag 11350 str "" } , 11351 url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=BC032 11352309" } } } , 11353 { 11354 type comment , 11355 version 0 , 11356 source { 11357 { 11358 src { 11359 db "UCSC" , 11360 tag 11361 str "" } , 11362 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position= 11363BC032309" } } } , 11364 { 11365 type comment , 11366 version 0 , 11367 source { 11368 { 11369 src { 11370 db "KEGG" , 11371 tag 11372 str "" } , 11373 url "http://www.genome.ad.jp/dbget-bin/www_bget?hsa:13" } } } , 11374 { 11375 type comment , 11376 version 0 , 11377 source { 11378 { 11379 src { 11380 db "MGC" , 11381 tag 11382 str "BC032309" } , 11383 anchor "MGC" , 11384 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC032309" } } } } } , 11385 { 11386 type comment , 11387 heading "Pathways" , 11388 version 0 , 11389 comment { 11390 { 11391 type comment , 11392 text "KEGG pathway: Butanoate metabolism" , 11393 version 0 , 11394 source { 11395 { 11396 src { 11397 db "00650" , 11398 tag 11399 str "00650" } , 11400 anchor "00650" , 11401 url "http://www.genome.jp/dbget-bin/show_pathway?hsa00650+13" } } } , 11402 { 11403 type comment , 11404 text "KEGG pathway: Alkaloid biosynthesis II" , 11405 version 0 , 11406 source { 11407 { 11408 src { 11409 db "00960" , 11410 tag 11411 str "00960" } , 11412 anchor "00960" , 11413 url "http://www.genome.jp/dbget-bin/show_pathway?hsa00960+13" } } } , 11414 { 11415 type comment , 11416 text "KEGG pathway: 2,4-Dichlorobenzoate degradation" , 11417 version 0 , 11418 source { 11419 { 11420 src { 11421 db "00623" , 11422 tag 11423 str "00623" } , 11424 anchor "00623" , 11425 url "http://www.genome.jp/dbget-bin/show_pathway?hsa00623+13" } } } , 11426 { 11427 type comment , 11428 text "KEGG pathway: Pentose and glucuronate interconversions" , 11429 version 0 , 11430 source { 11431 { 11432 src { 11433 db "00040" , 11434 tag 11435 str "00040" } , 11436 anchor "00040" , 11437 url "http://www.genome.jp/dbget-bin/show_pathway?hsa00040+13" } } } , 11438 { 11439 type comment , 11440 text "KEGG pathway: Glycosylphosphatidylinositol(GPI)-anchor 11441 biosynthesis" , 11442 version 0 , 11443 source { 11444 { 11445 src { 11446 db "00563" , 11447 tag 11448 str "00563" } , 11449 anchor "00563" , 11450 url "http://www.genome.jp/dbget-bin/show_pathway?hsa00563+13" } } } } } } , 11451 unique-keys { 11452 { 11453 db "LocusID" , 11454 tag 11455 id 13 } , 11456 { 11457 db "MIM" , 11458 tag 11459 id 600338 } } , 11460 xtra-index-terms { 11461 "LOC13" } } 11462Entrezgene ::= { 11463 track-info { 11464 geneid 14 , 11465 status live , 11466 create-date 11467 std { 11468 year 2003 , 11469 month 8 , 11470 day 28 , 11471 hour 20 , 11472 minute 30 , 11473 second 0 } , 11474 update-date 11475 std { 11476 year 2005 , 11477 month 4 , 11478 day 14 , 11479 hour 13 , 11480 minute 15 , 11481 second 0 } } , 11482 type protein-coding , 11483 source { 11484 genome genomic , 11485 origin natural , 11486 org { 11487 taxname "Homo sapiens" , 11488 common "human" , 11489 db { 11490 { 11491 db "taxon" , 11492 tag 11493 id 9606 } } , 11494 syn { 11495 "man" } , 11496 orgname { 11497 name 11498 binomial { 11499 genus "Homo" , 11500 species "sapiens" } , 11501 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 11502 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 11503 Hominidae; Homo" , 11504 gcode 1 , 11505 mgcode 2 , 11506 div "PRI" } } , 11507 subtype { 11508 { 11509 subtype chromosome , 11510 name "2" } } } , 11511 gene { 11512 locus "AAMP" , 11513 desc "angio-associated, migratory cell protein" , 11514 maploc "2q35" , 11515 db { 11516 { 11517 db "MIM" , 11518 tag 11519 id 603488 } } , 11520 locus-tag "HGNC:18" } , 11521 prot { 11522 name { 11523 "angio-associated, migratory cell protein" } } , 11524 summary "The gene product is an immunoglobulin-type protein. It is found to 11525 be expressed strongly in endothelial cells, cytotrophoblasts, and poorly 11526 differentiated colon adenocarcinoma cells found in lymphatics. The protein 11527 contains a heparin-binding domain and mediates heparin-sensitive cell 11528 adhesion." , 11529 location { 11530 { 11531 display-str "2q35" , 11532 method 11533 map-type cyto } } , 11534 gene-source { 11535 src "LocusLink" , 11536 src-int 14 , 11537 src-str2 "14" , 11538 gene-display FALSE , 11539 locus-display FALSE , 11540 extra-terms FALSE } , 11541 locus { 11542 { 11543 type genomic , 11544 heading "Reference" , 11545 accession "NC_000002" , 11546 version 9 , 11547 seqs { 11548 int { 11549 from 218954357 , 11550 to 218960364 , 11551 strand minus , 11552 id 11553 gi 51511462 } } , 11554 products { 11555 { 11556 type mRNA , 11557 heading "Reference" , 11558 accession "NM_001087" , 11559 version 1 , 11560 genomic-coords { 11561 mix { 11562 int { 11563 from 218954357 , 11564 to 218954835 , 11565 strand minus , 11566 id 11567 gi 51511462 } , 11568 int { 11569 from 218955247 , 11570 to 218955401 , 11571 strand minus , 11572 id 11573 gi 51511462 } , 11574 int { 11575 from 218955598 , 11576 to 218955688 , 11577 strand minus , 11578 id 11579 gi 51511462 } , 11580 int { 11581 from 218955806 , 11582 to 218955909 , 11583 strand minus , 11584 id 11585 gi 51511462 } , 11586 int { 11587 from 218956058 , 11588 to 218956173 , 11589 strand minus , 11590 id 11591 gi 51511462 } , 11592 int { 11593 from 218956291 , 11594 to 218956374 , 11595 strand minus , 11596 id 11597 gi 51511462 } , 11598 int { 11599 from 218956670 , 11600 to 218956814 , 11601 strand minus , 11602 id 11603 gi 51511462 } , 11604 int { 11605 from 218957074 , 11606 to 218957213 , 11607 strand minus , 11608 id 11609 gi 51511462 } , 11610 int { 11611 from 218957721 , 11612 to 218957840 , 11613 strand minus , 11614 id 11615 gi 51511462 } , 11616 int { 11617 from 218959609 , 11618 to 218959761 , 11619 strand minus , 11620 id 11621 gi 51511462 } , 11622 int { 11623 from 218960193 , 11624 to 218960364 , 11625 strand minus , 11626 id 11627 gi 51511462 } } } , 11628 seqs { 11629 whole 11630 gi 4557228 } , 11631 products { 11632 { 11633 type peptide , 11634 heading "Reference" , 11635 accession "NP_001078" , 11636 version 1 , 11637 genomic-coords { 11638 packed-int { 11639 { 11640 from 218954760 , 11641 to 218954835 , 11642 strand minus , 11643 id 11644 gi 51511462 } , 11645 { 11646 from 218955247 , 11647 to 218955401 , 11648 strand minus , 11649 id 11650 gi 51511462 } , 11651 { 11652 from 218955598 , 11653 to 218955688 , 11654 strand minus , 11655 id 11656 gi 51511462 } , 11657 { 11658 from 218955806 , 11659 to 218955909 , 11660 strand minus , 11661 id 11662 gi 51511462 } , 11663 { 11664 from 218956058 , 11665 to 218956173 , 11666 strand minus , 11667 id 11668 gi 51511462 } , 11669 { 11670 from 218956291 , 11671 to 218956374 , 11672 strand minus , 11673 id 11674 gi 51511462 } , 11675 { 11676 from 218956670 , 11677 to 218956814 , 11678 strand minus , 11679 id 11680 gi 51511462 } , 11681 { 11682 from 218957074 , 11683 to 218957213 , 11684 strand minus , 11685 id 11686 gi 51511462 } , 11687 { 11688 from 218957721 , 11689 to 218957840 , 11690 strand minus , 11691 id 11692 gi 51511462 } , 11693 { 11694 from 218959609 , 11695 to 218959761 , 11696 strand minus , 11697 id 11698 gi 51511462 } , 11699 { 11700 from 218960193 , 11701 to 218960364 , 11702 strand minus , 11703 id 11704 gi 51511462 } } } , 11705 seqs { 11706 whole 11707 gi 4557229 } } } } } } , 11708 { 11709 type genomic , 11710 heading "Reference" , 11711 accession "NT_005403" , 11712 version 15 , 11713 seqs { 11714 int { 11715 from 69338267 , 11716 to 69344274 , 11717 strand minus , 11718 id 11719 gi 51461028 } } , 11720 products { 11721 { 11722 type mRNA , 11723 heading "Reference" , 11724 accession "NM_001087" , 11725 version 1 , 11726 genomic-coords { 11727 mix { 11728 int { 11729 from 69338267 , 11730 to 69338745 , 11731 strand minus , 11732 id 11733 gi 51461028 } , 11734 int { 11735 from 69339157 , 11736 to 69339311 , 11737 strand minus , 11738 id 11739 gi 51461028 } , 11740 int { 11741 from 69339508 , 11742 to 69339598 , 11743 strand minus , 11744 id 11745 gi 51461028 } , 11746 int { 11747 from 69339716 , 11748 to 69339819 , 11749 strand minus , 11750 id 11751 gi 51461028 } , 11752 int { 11753 from 69339968 , 11754 to 69340083 , 11755 strand minus , 11756 id 11757 gi 51461028 } , 11758 int { 11759 from 69340201 , 11760 to 69340284 , 11761 strand minus , 11762 id 11763 gi 51461028 } , 11764 int { 11765 from 69340580 , 11766 to 69340724 , 11767 strand minus , 11768 id 11769 gi 51461028 } , 11770 int { 11771 from 69340984 , 11772 to 69341123 , 11773 strand minus , 11774 id 11775 gi 51461028 } , 11776 int { 11777 from 69341631 , 11778 to 69341750 , 11779 strand minus , 11780 id 11781 gi 51461028 } , 11782 int { 11783 from 69343519 , 11784 to 69343671 , 11785 strand minus , 11786 id 11787 gi 51461028 } , 11788 int { 11789 from 69344103 , 11790 to 69344274 , 11791 strand minus , 11792 id 11793 gi 51461028 } } } , 11794 seqs { 11795 whole 11796 gi 4557228 } , 11797 products { 11798 { 11799 type peptide , 11800 heading "Reference" , 11801 accession "NP_001078" , 11802 version 1 , 11803 genomic-coords { 11804 packed-int { 11805 { 11806 from 69338670 , 11807 to 69338745 , 11808 strand minus , 11809 id 11810 gi 51461028 } , 11811 { 11812 from 69339157 , 11813 to 69339311 , 11814 strand minus , 11815 id 11816 gi 51461028 } , 11817 { 11818 from 69339508 , 11819 to 69339598 , 11820 strand minus , 11821 id 11822 gi 51461028 } , 11823 { 11824 from 69339716 , 11825 to 69339819 , 11826 strand minus , 11827 id 11828 gi 51461028 } , 11829 { 11830 from 69339968 , 11831 to 69340083 , 11832 strand minus , 11833 id 11834 gi 51461028 } , 11835 { 11836 from 69340201 , 11837 to 69340284 , 11838 strand minus , 11839 id 11840 gi 51461028 } , 11841 { 11842 from 69340580 , 11843 to 69340724 , 11844 strand minus , 11845 id 11846 gi 51461028 } , 11847 { 11848 from 69340984 , 11849 to 69341123 , 11850 strand minus , 11851 id 11852 gi 51461028 } , 11853 { 11854 from 69341631 , 11855 to 69341750 , 11856 strand minus , 11857 id 11858 gi 51461028 } , 11859 { 11860 from 69343519 , 11861 to 69343671 , 11862 strand minus , 11863 id 11864 gi 51461028 } , 11865 { 11866 from 69344103 , 11867 to 69344274 , 11868 strand minus , 11869 id 11870 gi 51461028 } } } , 11871 seqs { 11872 whole 11873 gi 4557229 } } } } } } , 11874 { 11875 type genomic , 11876 heading "Reference" , 11877 accession "NT_086634" , 11878 version 1 , 11879 seqs { 11880 int { 11881 from 23772483 , 11882 to 23778490 , 11883 strand minus , 11884 id 11885 gi 51463854 } } , 11886 products { 11887 { 11888 type mRNA , 11889 heading "Reference" , 11890 accession "NM_001087" , 11891 version 1 , 11892 genomic-coords { 11893 mix { 11894 int { 11895 from 23772483 , 11896 to 23772961 , 11897 strand minus , 11898 id 11899 gi 51463854 } , 11900 int { 11901 from 23773373 , 11902 to 23773527 , 11903 strand minus , 11904 id 11905 gi 51463854 } , 11906 int { 11907 from 23773724 , 11908 to 23773814 , 11909 strand minus , 11910 id 11911 gi 51463854 } , 11912 int { 11913 from 23773932 , 11914 to 23774035 , 11915 strand minus , 11916 id 11917 gi 51463854 } , 11918 int { 11919 from 23774184 , 11920 to 23774299 , 11921 strand minus , 11922 id 11923 gi 51463854 } , 11924 int { 11925 from 23774417 , 11926 to 23774500 , 11927 strand minus , 11928 id 11929 gi 51463854 } , 11930 int { 11931 from 23774796 , 11932 to 23774940 , 11933 strand minus , 11934 id 11935 gi 51463854 } , 11936 int { 11937 from 23775200 , 11938 to 23775339 , 11939 strand minus , 11940 id 11941 gi 51463854 } , 11942 int { 11943 from 23775847 , 11944 to 23775966 , 11945 strand minus , 11946 id 11947 gi 51463854 } , 11948 int { 11949 from 23777735 , 11950 to 23777887 , 11951 strand minus , 11952 id 11953 gi 51463854 } , 11954 int { 11955 from 23778319 , 11956 to 23778490 , 11957 strand minus , 11958 id 11959 gi 51463854 } } } , 11960 seqs { 11961 whole 11962 gi 4557228 } , 11963 products { 11964 { 11965 type peptide , 11966 heading "Reference" , 11967 accession "NP_001078" , 11968 version 1 , 11969 genomic-coords { 11970 packed-int { 11971 { 11972 from 23772886 , 11973 to 23772961 , 11974 strand minus , 11975 id 11976 gi 51463854 } , 11977 { 11978 from 23773373 , 11979 to 23773527 , 11980 strand minus , 11981 id 11982 gi 51463854 } , 11983 { 11984 from 23773724 , 11985 to 23773814 , 11986 strand minus , 11987 id 11988 gi 51463854 } , 11989 { 11990 from 23773932 , 11991 to 23774035 , 11992 strand minus , 11993 id 11994 gi 51463854 } , 11995 { 11996 from 23774184 , 11997 to 23774299 , 11998 strand minus , 11999 id 12000 gi 51463854 } , 12001 { 12002 from 23774417 , 12003 to 23774500 , 12004 strand minus , 12005 id 12006 gi 51463854 } , 12007 { 12008 from 23774796 , 12009 to 23774940 , 12010 strand minus , 12011 id 12012 gi 51463854 } , 12013 { 12014 from 23775200 , 12015 to 23775339 , 12016 strand minus , 12017 id 12018 gi 51463854 } , 12019 { 12020 from 23775847 , 12021 to 23775966 , 12022 strand minus , 12023 id 12024 gi 51463854 } , 12025 { 12026 from 23777735 , 12027 to 23777887 , 12028 strand minus , 12029 id 12030 gi 51463854 } , 12031 { 12032 from 23778319 , 12033 to 23778490 , 12034 strand minus , 12035 id 12036 gi 51463854 } } } , 12037 seqs { 12038 whole 12039 gi 4557229 } } } } } } } , 12040 properties { 12041 { 12042 type comment , 12043 label "Nomenclature" , 12044 version 0 , 12045 source { 12046 { 12047 anchor "HUGO Gene Nomenclature Committee" } } , 12048 properties { 12049 { 12050 type property , 12051 label "Official Symbol" , 12052 text "AAMP" , 12053 version 0 } , 12054 { 12055 type property , 12056 label "Official Full Name" , 12057 text "angio-associated, migratory cell protein" , 12058 version 0 } } } , 12059 { 12060 type comment , 12061 heading "GeneOntology" , 12062 version 0 , 12063 source { 12064 { 12065 pre-text "Provided by" , 12066 anchor "GOA" , 12067 url "http://www.ebi.ac.uk/GOA/" } } , 12068 comment { 12069 { 12070 type comment , 12071 label "Function" , 12072 version 0 , 12073 comment { 12074 { 12075 type comment , 12076 version 0 , 12077 refs { 12078 pmid 7743515 } , 12079 source { 12080 { 12081 src { 12082 db "GO" , 12083 tag 12084 id 8201 } , 12085 anchor "heparin binding" , 12086 post-text "evidence: TAS" } } } } } , 12087 { 12088 type comment , 12089 label "Process" , 12090 version 0 , 12091 comment { 12092 { 12093 type comment , 12094 version 0 , 12095 source { 12096 { 12097 src { 12098 db "GO" , 12099 tag 12100 id 6928 } , 12101 anchor "cell motility" , 12102 post-text "evidence: NR" } } } } } } } } , 12103 homology { 12104 { 12105 type comment , 12106 heading "Mouse, Rat" , 12107 version 0 , 12108 source { 12109 { 12110 src { 12111 db "HomoloGene" , 12112 tag 12113 id 846 } , 12114 anchor "Map Viewer" , 12115 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=2&M 12116APS=genes-r-org/rat-chr/human%3A2,genes-r-org/mouse-chr/human%3A2,genes-r-org/ 12117human-chr2&query=e%3A14[id]+AND+gene[obj_type]&QSTR=aamp&cmd=focus&fill=10" } } } } , 12118 comments { 12119 { 12120 type comment , 12121 heading "LocusTagLink" , 12122 version 0 , 12123 source { 12124 { 12125 src { 12126 db "HGNC" , 12127 tag 12128 id 18 } } } } , 12129 { 12130 type comment , 12131 heading "RefSeq Status" , 12132 label "REVIEWED" , 12133 version 0 } , 12134 { 12135 type comment , 12136 version 0 , 12137 refs { 12138 pmid 12477932 , 12139 pmid 11969303 , 12140 pmid 10329261 , 12141 pmid 8660919 , 12142 pmid 7743515 } } , 12143 { 12144 type comment , 12145 heading "Markers (Sequence Tagged Sites/STS)" , 12146 version 0 , 12147 comment { 12148 { 12149 type comment , 12150 version 0 , 12151 source { 12152 { 12153 src { 12154 db "UniSTS" , 12155 tag 12156 id 52581 } , 12157 anchor "SGC31591" , 12158 post-text "(e-PCR)" } } , 12159 comment { 12160 { 12161 type other , 12162 label "Alternate name" , 12163 text "CM4.18" , 12164 version 0 } , 12165 { 12166 type other , 12167 label "Alternate name" , 12168 text "GC" , 12169 version 0 } , 12170 { 12171 type other , 12172 label "Alternate name" , 12173 text "RH23156" , 12174 version 0 } , 12175 { 12176 type other , 12177 label "Alternate name" , 12178 text "STS4-18" , 12179 version 0 } } } } } , 12180 { 12181 type comment , 12182 heading "NCBI Reference Sequences (RefSeq)" , 12183 version 0 , 12184 products { 12185 { 12186 type mRNA , 12187 heading "mRNA Sequence" , 12188 accession "NM_001087" , 12189 version 2 , 12190 source { 12191 { 12192 src { 12193 db "Nucleotide" , 12194 tag 12195 id 55743074 } , 12196 anchor "NM_001087" } } , 12197 seqs { 12198 whole 12199 gi 55743074 } , 12200 products { 12201 { 12202 type peptide , 12203 heading "Product" , 12204 accession "NP_001078" , 12205 version 2 , 12206 source { 12207 { 12208 src { 12209 db "Protein" , 12210 tag 12211 id 55743075 } , 12212 anchor "NP_001078" , 12213 post-text "angio-associated, migratory cell protein" } } , 12214 seqs { 12215 whole 12216 gi 55743075 } , 12217 comment { 12218 { 12219 type other , 12220 heading "Conserved Domains" , 12221 version 0 , 12222 source { 12223 { 12224 src { 12225 db "PROT_CDD" , 12226 tag 12227 id 55743075 } , 12228 pre-text "(2)" , 12229 anchor "summary" } } , 12230 comment { 12231 { 12232 type other , 12233 version 0 , 12234 source { 12235 { 12236 src { 12237 db "CDD" , 12238 tag 12239 id 5398 } , 12240 anchor "cd00200: WD40; WD40 domain, found in a 12241 number of eukaryotic proteins that cover a wide variety of functions 12242 including adaptor/regulatory modules in signal transduction, pre-mRNA 12243 processing and cytoskeleton assembly" } } , 12244 comment { 12245 { 12246 type other , 12247 text "Location: 86 - 386 Blast Score: 457" , 12248 version 0 } , 12249 { 12250 type other , 12251 text "Location: 325 - 430 Blast Score: 176" , 12252 version 0 } } } } } } } } , 12253 comment { 12254 { 12255 type other , 12256 heading "Source Sequence" , 12257 version 0 , 12258 source { 12259 { 12260 src { 12261 db "Nucleotide" , 12262 tag 12263 str "BG534787,CN277005,M95627" } , 12264 anchor "BG534787,CN277005,M95627" } } , 12265 comment { 12266 { 12267 type other , 12268 version 0 } } } } } } } , 12269 { 12270 type comment , 12271 heading "Related Sequences" , 12272 version 0 , 12273 products { 12274 { 12275 type mRNA , 12276 heading "mRNA" , 12277 accession "AB209790" , 12278 version 1 , 12279 source { 12280 { 12281 src { 12282 db "Nucleotide" , 12283 tag 12284 id 62089165 } , 12285 anchor "AB209790" } } , 12286 seqs { 12287 whole 12288 gi 62089165 } , 12289 products { 12290 { 12291 type peptide , 12292 accession "BAD93027" , 12293 version 1 , 12294 source { 12295 { 12296 src { 12297 db "Protein" , 12298 tag 12299 id 62089166 } , 12300 anchor "BAD93027" } } , 12301 seqs { 12302 whole 12303 gi 62089166 } } } } , 12304 { 12305 type mRNA , 12306 heading "mRNA" , 12307 accession "AK131047" , 12308 version 1 , 12309 source { 12310 { 12311 src { 12312 db "Nucleotide" , 12313 tag 12314 id 34528300 } , 12315 anchor "AK131047" } } , 12316 seqs { 12317 whole 12318 gi 34528300 } , 12319 products { 12320 { 12321 type peptide , 12322 text "None" , 12323 version 0 } } } , 12324 { 12325 type mRNA , 12326 heading "mRNA" , 12327 accession "BC008809" , 12328 version 2 , 12329 source { 12330 { 12331 src { 12332 db "Nucleotide" , 12333 tag 12334 id 39644831 } , 12335 anchor "BC008809" } } , 12336 seqs { 12337 whole 12338 gi 39644831 } , 12339 products { 12340 { 12341 type peptide , 12342 accession "AAH08809" , 12343 version 2 , 12344 source { 12345 { 12346 src { 12347 db "Protein" , 12348 tag 12349 id 39644832 } , 12350 anchor "AAH08809" } } , 12351 seqs { 12352 whole 12353 gi 39644832 } } } } , 12354 { 12355 type mRNA , 12356 heading "mRNA" , 12357 accession "BC014122" , 12358 version 2 , 12359 source { 12360 { 12361 src { 12362 db "Nucleotide" , 12363 tag 12364 id 33874729 } , 12365 anchor "BC014122" } } , 12366 seqs { 12367 whole 12368 gi 33874729 } , 12369 products { 12370 { 12371 type peptide , 12372 accession "AAH14122" , 12373 version 1 , 12374 source { 12375 { 12376 src { 12377 db "Protein" , 12378 tag 12379 id 33874730 } , 12380 anchor "AAH14122" } } , 12381 seqs { 12382 whole 12383 gi 33874730 } } } } , 12384 { 12385 type mRNA , 12386 heading "mRNA" , 12387 accession "BC020244" , 12388 version 1 , 12389 source { 12390 { 12391 src { 12392 db "Nucleotide" , 12393 tag 12394 id 18044383 } , 12395 anchor "BC020244" } } , 12396 seqs { 12397 whole 12398 gi 18044383 } , 12399 products { 12400 { 12401 type peptide , 12402 accession "AAH20244" , 12403 version 1 , 12404 source { 12405 { 12406 src { 12407 db "Protein" , 12408 tag 12409 id 18044384 } , 12410 anchor "AAH20244" } } , 12411 seqs { 12412 whole 12413 gi 18044384 } } } } , 12414 { 12415 type mRNA , 12416 heading "mRNA" , 12417 accession "BC039866" , 12418 version 1 , 12419 source { 12420 { 12421 src { 12422 db "Nucleotide" , 12423 tag 12424 id 25123215 } , 12425 anchor "BC039866" } } , 12426 seqs { 12427 whole 12428 gi 25123215 } , 12429 products { 12430 { 12431 type peptide , 12432 accession "AAH39866" , 12433 version 1 , 12434 source { 12435 { 12436 src { 12437 db "Protein" , 12438 tag 12439 id 56200511 } , 12440 anchor "AAH39866" } } , 12441 seqs { 12442 whole 12443 gi 56200511 } } } } , 12444 { 12445 type mRNA , 12446 heading "mRNA" , 12447 accession "CR456755" , 12448 version 1 , 12449 source { 12450 { 12451 src { 12452 db "Nucleotide" , 12453 tag 12454 id 48145626 } , 12455 anchor "CR456755" } } , 12456 seqs { 12457 whole 12458 gi 48145626 } , 12459 products { 12460 { 12461 type peptide , 12462 accession "CAG33036" , 12463 version 1 , 12464 source { 12465 { 12466 src { 12467 db "Protein" , 12468 tag 12469 id 48145627 } , 12470 anchor "CAG33036" } } , 12471 seqs { 12472 whole 12473 gi 48145627 } } } } , 12474 { 12475 type mRNA , 12476 heading "mRNA" , 12477 accession "M95627" , 12478 version 1 , 12479 source { 12480 { 12481 src { 12482 db "Nucleotide" , 12483 tag 12484 id 870802 } , 12485 anchor "M95627" } } , 12486 seqs { 12487 whole 12488 gi 870802 } , 12489 products { 12490 { 12491 type peptide , 12492 accession "AAA68889" , 12493 version 1 , 12494 source { 12495 { 12496 src { 12497 db "Protein" , 12498 tag 12499 id 870803 } , 12500 anchor "AAA68889" } } , 12501 seqs { 12502 whole 12503 gi 870803 } } } } , 12504 { 12505 type other , 12506 text "None" , 12507 version 0 , 12508 products { 12509 { 12510 type peptide , 12511 accession "Q13685" , 12512 version 0 , 12513 source { 12514 { 12515 src { 12516 db "Protein" , 12517 tag 12518 id 3121739 } , 12519 anchor "Q13685" } } , 12520 seqs { 12521 whole 12522 gi 3121739 } } } } } } , 12523 { 12524 type comment , 12525 heading "Additional Links" , 12526 version 0 , 12527 comment { 12528 { 12529 type comment , 12530 version 0 , 12531 source { 12532 { 12533 src { 12534 db "Evidence Viewer" , 12535 tag 12536 str "14" } , 12537 anchor "Evidence Viewer" , 12538 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 12539g=NT_005403.15&gene=AAMP&lid=14&from=69338268&to=69344275" } } } , 12540 { 12541 type comment , 12542 version 0 , 12543 source { 12544 { 12545 src { 12546 db "ModelMaker" , 12547 tag 12548 str "14" } , 12549 anchor "ModelMaker" , 12550 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 1255106&contig=NT_005403.15&gene=AAMP&lid=14" } } } , 12552 { 12553 type comment , 12554 text "UniGene" , 12555 version 0 , 12556 xtra-properties { 12557 { 12558 tag "UNIGENE" , 12559 value "Hs.83347" } } , 12560 source { 12561 { 12562 src { 12563 db "UniGene" , 12564 tag 12565 str "Hs.83347" } , 12566 anchor "Hs.83347" , 12567 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=83 12568347" } } } , 12569 { 12570 type comment , 12571 text "MIM" , 12572 version 0 , 12573 source { 12574 { 12575 src { 12576 db "MIM" , 12577 tag 12578 str "603488" } , 12579 anchor "603488" } } } , 12580 { 12581 type comment , 12582 version 0 , 12583 source { 12584 { 12585 src { 12586 db "HomoloGene" , 12587 tag 12588 str "14" } , 12589 anchor "HomoloGene" , 12590 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 1259114[loc]&TAXID=9606" } } } , 12592 { 12593 type comment , 12594 version 0 , 12595 source { 12596 { 12597 src { 12598 db "AceView" , 12599 tag 12600 id 14 } , 12601 anchor "AceView" , 12602 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 12603ocusid&org=9606&l=14" } } } , 12604 { 12605 type comment , 12606 version 0 , 12607 source { 12608 { 12609 src { 12610 db "GDB" , 12611 tag 12612 str "GDB:4573993" } } } } , 12613 { 12614 type comment , 12615 version 0 , 12616 source { 12617 { 12618 src { 12619 db "Ensembl" , 12620 tag 12621 str "" } , 12622 url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=AB209 12623790" } } } , 12624 { 12625 type comment , 12626 version 0 , 12627 source { 12628 { 12629 src { 12630 db "UCSC" , 12631 tag 12632 str "" } , 12633 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position= 12634AB209790" } } } , 12635 { 12636 type comment , 12637 version 0 , 12638 source { 12639 { 12640 src { 12641 db "MGC" , 12642 tag 12643 str "BC014122" } , 12644 anchor "MGC" , 12645 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC014122" } } } } } } , 12646 unique-keys { 12647 { 12648 db "LocusID" , 12649 tag 12650 id 14 } , 12651 { 12652 db "MIM" , 12653 tag 12654 id 603488 } } , 12655 xtra-index-terms { 12656 "LOC14" } } 12657Entrezgene ::= { 12658 track-info { 12659 geneid 15 , 12660 status live , 12661 create-date 12662 std { 12663 year 2003 , 12664 month 8 , 12665 day 28 , 12666 hour 20 , 12667 minute 30 , 12668 second 0 } , 12669 update-date 12670 std { 12671 year 2005 , 12672 month 4 , 12673 day 14 , 12674 hour 13 , 12675 minute 15 , 12676 second 0 } } , 12677 type protein-coding , 12678 source { 12679 genome genomic , 12680 origin natural , 12681 org { 12682 taxname "Homo sapiens" , 12683 common "human" , 12684 db { 12685 { 12686 db "taxon" , 12687 tag 12688 id 9606 } } , 12689 syn { 12690 "man" } , 12691 orgname { 12692 name 12693 binomial { 12694 genus "Homo" , 12695 species "sapiens" } , 12696 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 12697 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; 12698 Hominidae; Homo" , 12699 gcode 1 , 12700 mgcode 2 , 12701 div "PRI" } } , 12702 subtype { 12703 { 12704 subtype chromosome , 12705 name "17" } } } , 12706 gene { 12707 locus "AANAT" , 12708 desc "arylalkylamine N-acetyltransferase" , 12709 maploc "17q25" , 12710 db { 12711 { 12712 db "MIM" , 12713 tag 12714 id 600950 } } , 12715 syn { 12716 "SNAT" , 12717 "AA-NAT" } , 12718 locus-tag "HGNC:19" } , 12719 prot { 12720 name { 12721 "arylalkylamine N-acetyltransferase" , 12722 "serotonin N-acetyltransferase" } } , 12723 summary "Arylalkylamine N-acetyltransferase belongs to the superfamily of 12724 acetyltransferases. It is the penultimate enzyme in melatonin synthesis and 12725 controls the night/day rhythm in melatonin production in the vertebrate 12726 pineal gland. Melatonin is essential for seasonal reproduction, modulates the 12727 function of the circadian clock in the suprachiasmatic nucleus, and 12728 influences activity and sleep. This enzyme is rapidly inactivated when 12729 animals are exposed to light at night. This protein is 80% identical to sheep 12730 and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a 12731 multifactorial genetic diseases such as altered behavior in sleep/wake cycle." , 12732 location { 12733 { 12734 display-str "17q25" , 12735 method 12736 map-type cyto } } , 12737 gene-source { 12738 src "LocusLink" , 12739 src-int 15 , 12740 src-str2 "15" , 12741 gene-display FALSE , 12742 locus-display FALSE , 12743 extra-terms FALSE } , 12744 locus { 12745 { 12746 type genomic , 12747 heading "Reference" , 12748 accession "NC_000017" , 12749 version 9 , 12750 seqs { 12751 int { 12752 from 71975245 , 12753 to 71977793 , 12754 strand plus , 12755 id 12756 gi 51511734 } } , 12757 products { 12758 { 12759 type mRNA , 12760 heading "Reference" , 12761 accession "NM_001088" , 12762 version 1 , 12763 genomic-coords { 12764 mix { 12765 int { 12766 from 71975245 , 12767 to 71975403 , 12768 strand plus , 12769 id 12770 gi 51511734 } , 12771 int { 12772 from 71976348 , 12773 to 71976585 , 12774 strand plus , 12775 id 12776 gi 51511734 } , 12777 int { 12778 from 71976849 , 12779 to 71977003 , 12780 strand plus , 12781 id 12782 gi 51511734 } , 12783 int { 12784 from 71977341 , 12785 to 71977793 , 12786 strand plus , 12787 id 12788 gi 51511734 } } } , 12789 seqs { 12790 whole 12791 gi 4501844 } , 12792 products { 12793 { 12794 type peptide , 12795 heading "Reference" , 12796 accession "NP_001079" , 12797 version 1 , 12798 genomic-coords { 12799 packed-int { 12800 { 12801 from 71976423 , 12802 to 71976585 , 12803 strand plus , 12804 id 12805 gi 51511734 } , 12806 { 12807 from 71976849 , 12808 to 71977003 , 12809 strand plus , 12810 id 12811 gi 51511734 } , 12812 { 12813 from 71977341 , 12814 to 71977646 , 12815 strand plus , 12816 id 12817 gi 51511734 } } } , 12818 seqs { 12819 whole 12820 gi 4501845 } , 12821 comment { 12822 { 12823 type property , 12824 label "EC" , 12825 text "2.3.1.87" , 12826 version 0 , 12827 xtra-properties { 12828 { 12829 tag "EC" , 12830 value "2.3.1.87" } } } } } } } } } , 12831 { 12832 type genomic , 12833 heading "Reference" , 12834 accession "NT_010641" , 12835 version 15 , 12836 seqs { 12837 int { 12838 from 8389922 , 12839 to 8392470 , 12840 strand plus , 12841 id 12842 gi 51474120 } } , 12843 products { 12844 { 12845 type mRNA , 12846 heading "Reference" , 12847 accession "NM_001088" , 12848 version 1 , 12849 genomic-coords { 12850 mix { 12851 int { 12852 from 8389922 , 12853 to 8390080 , 12854 strand plus , 12855 id 12856 gi 51474120 } , 12857 int { 12858 from 8391025 , 12859 to 8391262 , 12860 strand plus , 12861 id 12862 gi 51474120 } , 12863 int { 12864 from 8391526 , 12865 to 8391680 , 12866 strand plus , 12867 id 12868 gi 51474120 } , 12869 int { 12870 from 8392018 , 12871 to 8392470 , 12872 strand plus , 12873 id 12874 gi 51474120 } } } , 12875 seqs { 12876 whole 12877 gi 4501844 } , 12878 products { 12879 { 12880 type peptide , 12881 heading "Reference" , 12882 accession "NP_001079" , 12883 version 1 , 12884 genomic-coords { 12885 packed-int { 12886 { 12887 from 8391100 , 12888 to 8391262 , 12889 strand plus , 12890 id 12891 gi 51474120 } , 12892 { 12893 from 8391526 , 12894 to 8391680 , 12895 strand plus , 12896 id 12897 gi 51474120 } , 12898 { 12899 from 8392018 , 12900 to 8392323 , 12901 strand plus , 12902 id 12903 gi 51474120 } } } , 12904 seqs { 12905 whole 12906 gi 4501845 } , 12907 comment { 12908 { 12909 type property , 12910 label "EC" , 12911 text "2.3.1.87" , 12912 version 0 , 12913 xtra-properties { 12914 { 12915 tag "EC" , 12916 value "2.3.1.87" } } } } } } } } } , 12917 { 12918 type genomic , 12919 heading "Reference" , 12920 accession "NT_086886" , 12921 version 1 , 12922 seqs { 12923 int { 12924 from 11539555 , 12925 to 11542103 , 12926 strand plus , 12927 id 12928 gi 51474508 } } , 12929 products { 12930 { 12931 type mRNA , 12932 heading "Reference" , 12933 accession "NM_001088" , 12934 version 1 , 12935 genomic-coords { 12936 mix { 12937 int { 12938 from 11539555 , 12939 to 11539713 , 12940 strand plus , 12941 id 12942 gi 51474508 } , 12943 int { 12944 from 11540658 , 12945 to 11540895 , 12946 strand plus , 12947 id 12948 gi 51474508 } , 12949 int { 12950 from 11541159 , 12951 to 11541313 , 12952 strand plus , 12953 id 12954 gi 51474508 } , 12955 int { 12956 from 11541651 , 12957 to 11542103 , 12958 strand plus , 12959 id 12960 gi 51474508 } } } , 12961 seqs { 12962 whole 12963 gi 4501844 } , 12964 products { 12965 { 12966 type peptide , 12967 heading "Reference" , 12968 accession "NP_001079" , 12969 version 1 , 12970 genomic-coords { 12971 packed-int { 12972 { 12973 from 11540733 , 12974 to 11540895 , 12975 strand plus , 12976 id 12977 gi 51474508 } , 12978 { 12979 from 11541159 , 12980 to 11541313 , 12981 strand plus , 12982 id 12983 gi 51474508 } , 12984 { 12985 from 11541651 , 12986 to 11541956 , 12987 strand plus , 12988 id 12989 gi 51474508 } } } , 12990 seqs { 12991 whole 12992 gi 4501845 } , 12993 comment { 12994 { 12995 type property , 12996 label "EC" , 12997 text "2.3.1.87" , 12998 version 0 , 12999 xtra-properties { 13000 { 13001 tag "EC" , 13002 value "2.3.1.87" } } } } } } } } } } , 13003 properties { 13004 { 13005 type comment , 13006 label "Nomenclature" , 13007 version 0 , 13008 source { 13009 { 13010 anchor "HUGO Gene Nomenclature Committee" } } , 13011 properties { 13012 { 13013 type property , 13014 label "Official Symbol" , 13015 text "AANAT" , 13016 version 0 } , 13017 { 13018 type property , 13019 label "Official Full Name" , 13020 text "arylalkylamine N-acetyltransferase" , 13021 version 0 } } } , 13022 { 13023 type comment , 13024 heading "GeneOntology" , 13025 version 0 , 13026 source { 13027 { 13028 pre-text "Provided by" , 13029 anchor "GOA" , 13030 url "http://www.ebi.ac.uk/GOA/" } } , 13031 comment { 13032 { 13033 type comment , 13034 label "Function" , 13035 version 0 , 13036 comment { 13037 { 13038 type comment , 13039 version 0 , 13040 source { 13041 { 13042 src { 13043 db "GO" , 13044 tag 13045 id 8415 } , 13046 anchor "acyltransferase activity" , 13047 post-text "evidence: IEA" } } } , 13048 { 13049 type comment , 13050 version 0 , 13051 refs { 13052 pmid 8661026 } , 13053 source { 13054 { 13055 src { 13056 db "GO" , 13057 tag 13058 id 4059 } , 13059 anchor "aralkylamine N-acetyltransferase activity" , 13060 post-text "evidence: TAS" } } } , 13061 { 13062 type comment , 13063 version 0 , 13064 source { 13065 { 13066 src { 13067 db "GO" , 13068 tag 13069 id 16740 } , 13070 anchor "transferase activity" , 13071 post-text "evidence: IEA" } } } } } , 13072 { 13073 type comment , 13074 label "Process" , 13075 version 0 , 13076 comment { 13077 { 13078 type comment , 13079 version 0 , 13080 refs { 13081 pmid 8661026 } , 13082 source { 13083 { 13084 src { 13085 db "GO" , 13086 tag 13087 id 7623 } , 13088 anchor "circadian rhythm" , 13089 post-text "evidence: TAS" } } } } } } } } , 13090 homology { 13091 { 13092 type comment , 13093 heading "Mouse, Rat" , 13094 version 0 , 13095 source { 13096 { 13097 src { 13098 db "HomoloGene" , 13099 tag 13100 id 31013 } , 13101 anchor "Map Viewer" , 13102 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=17& 13103MAPS=genes-r-org/rat-chr/human%3A17,genes-r-org/mouse-chr/human%3A17,genes-r-o 13104rg/human-chr17&query=e%3A15[id]+AND+gene[obj_type]&QSTR=aanat&cmd=focus&fill=1 131050" } } } } , 13106 comments { 13107 { 13108 type comment , 13109 heading "LocusTagLink" , 13110 version 0 , 13111 source { 13112 { 13113 src { 13114 db "HGNC" , 13115 tag 13116 id 19 } } } } , 13117 { 13118 type comment , 13119 heading "RefSeq Status" , 13120 label "REVIEWED" , 13121 version 0 } , 13122 { 13123 type comment , 13124 version 0 , 13125 refs { 13126 pmid 15332344 , 13127 pmid 12736803 , 13128 pmid 12552951 , 13129 pmid 12477932 , 13130 pmid 12039872 , 13131 pmid 11934439 , 13132 pmid 11427721 , 13133 pmid 11336675 , 13134 pmid 11313340 , 13135 pmid 9238858 , 13136 pmid 8661026 , 13137 pmid 7502081 , 13138 pmid 2181999 } } , 13139 { 13140 type comment , 13141 heading "NCBI Reference Sequences (RefSeq)" , 13142 version 0 , 13143 products { 13144 { 13145 type mRNA , 13146 heading "mRNA Sequence" , 13147 accession "NM_001088" , 13148 version 1 , 13149 source { 13150 { 13151 src { 13152 db "Nucleotide" , 13153 tag 13154 id 4501844 } , 13155 anchor "NM_001088" } } , 13156 seqs { 13157 whole 13158 gi 4501844 } , 13159 products { 13160 { 13161 type peptide , 13162 heading "Product" , 13163 accession "NP_001079" , 13164 version 1 , 13165 source { 13166 { 13167 src { 13168 db "Protein" , 13169 tag 13170 id 4501845 } , 13171 anchor "NP_001079" , 13172 post-text "arylalkylamine N-acetyltransferase" } } , 13173 seqs { 13174 whole 13175 gi 4501845 } , 13176 comment { 13177 { 13178 type other , 13179 heading "Consensus CDS (CCDS)" , 13180 version 0 , 13181 source { 13182 { 13183 src { 13184 db "CCDS" , 13185 tag 13186 str "CCDS11745.1" } , 13187 anchor "CCDS11745.1" } } } , 13188 { 13189 type other , 13190 heading "Conserved Domains" , 13191 version 0 , 13192 source { 13193 { 13194 src { 13195 db "PROT_CDD" , 13196 tag 13197 id 4501845 } , 13198 pre-text "(1)" , 13199 anchor "summary" } } , 13200 comment { 13201 { 13202 type other , 13203 version 0 , 13204 source { 13205 { 13206 src { 13207 db "CDD" , 13208 tag 13209 id 25558 } , 13210 anchor "pfam00583: Acetyltransf_1; Acetyltransferase 13211 (GNAT) family" } } , 13212 comment { 13213 { 13214 type other , 13215 text "Location: 82 - 174 Blast Score: 94" , 13216 version 0 } } } } } } } } , 13217 comment { 13218 { 13219 type other , 13220 heading "Source Sequence" , 13221 version 0 , 13222 source { 13223 { 13224 src { 13225 db "Nucleotide" , 13226 tag 13227 str "U40347" } , 13228 anchor "U40347" } } , 13229 comment { 13230 { 13231 type other , 13232 version 0 } } } } } } } , 13233 { 13234 type comment , 13235 heading "Related Sequences" , 13236 version 0 , 13237 products { 13238 { 13239 type genomic , 13240 heading "Genomic" , 13241 accession "AB023793" , 13242 version 1 , 13243 source { 13244 { 13245 src { 13246 db "Nucleotide" , 13247 tag 13248 id 12248880 } , 13249 anchor "AB023793" } } , 13250 seqs { 13251 whole 13252 gi 12248880 } , 13253 products { 13254 { 13255 type peptide , 13256 accession "BAB20312" , 13257 version 1 , 13258 source { 13259 { 13260 src { 13261 db "Protein" , 13262 tag 13263 id 12248881 } , 13264 anchor "BAB20312" } } , 13265 seqs { 13266 whole 13267 gi 12248881 } } } } , 13268 { 13269 type genomic , 13270 heading "Genomic" , 13271 accession "AB023794" , 13272 version 1 , 13273 source { 13274 { 13275 src { 13276 db "Nucleotide" , 13277 tag 13278 id 12248882 } , 13279 anchor "AB023794" } } , 13280 seqs { 13281 whole 13282 gi 12248882 } , 13283 products { 13284 { 13285 type peptide , 13286 accession "BAB20313" , 13287 version 1 , 13288 source { 13289 { 13290 src { 13291 db "Protein" , 13292 tag 13293 id 12248883 } , 13294 anchor "BAB20313" } } , 13295 seqs { 13296 whole 13297 gi 12248883 } } } } , 13298 { 13299 type genomic , 13300 heading "Genomic" , 13301 accession "AB023795" , 13302 version 1 , 13303 source { 13304 { 13305 src { 13306 db "Nucleotide" , 13307 tag 13308 id 12248884 } , 13309 anchor "AB023795" } } , 13310 seqs { 13311 whole 13312 gi 12248884 } , 13313 products { 13314 { 13315 type peptide , 13316 accession "BAB20314" , 13317 version 1 , 13318 source { 13319 { 13320 src { 13321 db "Protein" , 13322 tag 13323 id 12248885 } , 13324 anchor "BAB20314" } } , 13325 seqs { 13326 whole 13327 gi 12248885 } } } } , 13328 { 13329 type genomic , 13330 heading "Genomic" , 13331 accession "AB023796" , 13332 version 1 , 13333 source { 13334 { 13335 src { 13336 db "Nucleotide" , 13337 tag 13338 id 12248886 } , 13339 anchor "AB023796" } } , 13340 seqs { 13341 whole 13342 gi 12248886 } , 13343 products { 13344 { 13345 type peptide , 13346 accession "BAB20315" , 13347 version 1 , 13348 source { 13349 { 13350 src { 13351 db "Protein" , 13352 tag 13353 id 12248887 } , 13354 anchor "BAB20315" } } , 13355 seqs { 13356 whole 13357 gi 12248887 } } } } , 13358 { 13359 type genomic , 13360 heading "Genomic" , 13361 accession "AB023797" , 13362 version 1 , 13363 source { 13364 { 13365 src { 13366 db "Nucleotide" , 13367 tag 13368 id 12248888 } , 13369 anchor "AB023797" } } , 13370 seqs { 13371 whole 13372 gi 12248888 } , 13373 products { 13374 { 13375 type peptide , 13376 accession "BAB20316" , 13377 version 1 , 13378 source { 13379 { 13380 src { 13381 db "Protein" , 13382 tag 13383 id 12248889 } , 13384 anchor "BAB20316" } } , 13385 seqs { 13386 whole 13387 gi 12248889 } } } } , 13388 { 13389 type genomic , 13390 heading "Genomic" , 13391 accession "AF360979" , 13392 version 1 , 13393 source { 13394 { 13395 src { 13396 db "Nucleotide" , 13397 tag 13398 id 13936890 } , 13399 anchor "AF360979" } } , 13400 seqs { 13401 whole 13402 gi 13936890 } , 13403 products { 13404 { 13405 type peptide , 13406 accession "AAK49981" , 13407 version 1 , 13408 source { 13409 { 13410 src { 13411 db "Protein" , 13412 tag 13413 id 13936891 } , 13414 anchor "AAK49981" } } , 13415 seqs { 13416 whole 13417 gi 13936891 } } } } , 13418 { 13419 type genomic , 13420 heading "Genomic" , 13421 accession "U40391" , 13422 version 1 , 13423 source { 13424 { 13425 src { 13426 db "Nucleotide" , 13427 tag 13428 id 1389593 } , 13429 anchor "U40391" } } , 13430 seqs { 13431 whole 13432 gi 1389593 } , 13433 products { 13434 { 13435 type peptide , 13436 accession "AAC50555" , 13437 version 1 , 13438 source { 13439 { 13440 src { 13441 db "Protein" , 13442 tag 13443 id 1389594 } , 13444 anchor "AAC50555" } } , 13445 seqs { 13446 whole 13447 gi 1389594 } } } } , 13448 { 13449 type mRNA , 13450 heading "mRNA" , 13451 accession "BC069434" , 13452 version 1 , 13453 source { 13454 { 13455 src { 13456 db "Nucleotide" , 13457 tag 13458 id 46854803 } , 13459 anchor "BC069434" } } , 13460 seqs { 13461 whole 13462 gi 46854803 } , 13463 products { 13464 { 13465 type peptide , 13466 accession "AAH69434" , 13467 version 1 , 13468 source { 13469 { 13470 src { 13471 db "Protein" , 13472 tag 13473 id 46854804 } , 13474 anchor "AAH69434" } } , 13475 seqs { 13476 whole 13477 gi 46854804 } } } } , 13478 { 13479 type mRNA , 13480 heading "mRNA" , 13481 accession "U40347" , 13482 version 1 , 13483 source { 13484 { 13485 src { 13486 db "Nucleotide" , 13487 tag 13488 id 1389591 } , 13489 anchor "U40347" } } , 13490 seqs { 13491 whole 13492 gi 1389591 } , 13493 products { 13494 { 13495 type peptide , 13496 accession "AAC50554" , 13497 version 1 , 13498 source { 13499 { 13500 src { 13501 db "Protein" , 13502 tag 13503 id 1389592 } , 13504 anchor "AAC50554" } } , 13505 seqs { 13506 whole 13507 gi 1389592 } } } } , 13508 { 13509 type other , 13510 text "None" , 13511 version 0 , 13512 products { 13513 { 13514 type peptide , 13515 accession "Q16613" , 13516 version 0 , 13517 source { 13518 { 13519 src { 13520 db "Protein" , 13521 tag 13522 id 11387096 } , 13523 anchor "Q16613" } } , 13524 seqs { 13525 whole 13526 gi 11387096 } } } } } } , 13527 { 13528 type comment , 13529 heading "Additional Links" , 13530 version 0 , 13531 comment { 13532 { 13533 type comment , 13534 version 0 , 13535 source { 13536 { 13537 src { 13538 db "Evidence Viewer" , 13539 tag 13540 str "15" } , 13541 anchor "Evidence Viewer" , 13542 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti 13543g=NT_010641.15&gene=AANAT&lid=15&from=8389923&to=8392471" } } } , 13544 { 13545 type comment , 13546 version 0 , 13547 source { 13548 { 13549 src { 13550 db "ModelMaker" , 13551 tag 13552 str "15" } , 13553 anchor "ModelMaker" , 13554 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96 1355506&contig=NT_010641.15&gene=AANAT&lid=15" } } } , 13556 { 13557 type comment , 13558 text "UniGene" , 13559 version 0 , 13560 xtra-properties { 13561 { 13562 tag "UNIGENE" , 13563 value "Hs.431417" } } , 13564 source { 13565 { 13566 src { 13567 db "UniGene" , 13568 tag 13569 str "Hs.431417" } , 13570 anchor "Hs.431417" , 13571 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=43 135721417" } } } , 13573 { 13574 type comment , 13575 text "MIM" , 13576 version 0 , 13577 source { 13578 { 13579 src { 13580 db "MIM" , 13581 tag 13582 str "600950" } , 13583 anchor "600950" } } } , 13584 { 13585 type comment , 13586 version 0 , 13587 source { 13588 { 13589 src { 13590 db "HomoloGene" , 13591 tag 13592 str "15" } , 13593 anchor "HomoloGene" , 13594 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 1359515[loc]&TAXID=9606" } } } , 13596 { 13597 type comment , 13598 version 0 , 13599 source { 13600 { 13601 src { 13602 db "AceView" , 13603 tag 13604 id 15 } , 13605 anchor "AceView" , 13606 url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l 13607ocusid&org=9606&l=15" } } } , 13608 { 13609 type comment , 13610 version 0 , 13611 source { 13612 { 13613 src { 13614 db "GDB" , 13615 tag 13616 str "GDB:700076" } } } } , 13617 { 13618 type comment , 13619 version 0 , 13620 source { 13621 { 13622 src { 13623 db "Ensembl" , 13624 tag 13625 str "" } , 13626 url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=U4034 136277" } } } , 13628 { 13629 type comment , 13630 version 0 , 13631 source { 13632 { 13633 src { 13634 db "UCSC" , 13635 tag 13636 str "" } , 13637 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position= 13638U40347" } } } , 13639 { 13640 type comment , 13641 version 0 , 13642 source { 13643 { 13644 src { 13645 db "KEGG" , 13646 tag 13647 str "" } , 13648 url "http://www.genome.ad.jp/dbget-bin/www_bget?hsa:15" } } } , 13649 { 13650 type comment , 13651 text "PharmGKB" , 13652 version 0 , 13653 source { 13654 { 13655 src { 13656 db "PharmGKB" , 13657 tag 13658 str "PA24366" } , 13659 anchor "PA24366" } } } , 13660 { 13661 type comment , 13662 version 0 , 13663 source { 13664 { 13665 src { 13666 db "MGC" , 13667 tag 13668 str "BC069434" } , 13669 anchor "MGC" , 13670 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC069434" } } } } } , 13671 { 13672 type comment , 13673 heading "Pathways" , 13674 version 0 , 13675 comment { 13676 { 13677 type comment , 13678 text "KEGG pathway: Tryptophan metabolism" , 13679 version 0 , 13680 source { 13681 { 13682 src { 13683 db "00380" , 13684 tag 13685 str "00380" } , 13686 anchor "00380" , 13687 url "http://www.genome.jp/dbget-bin/show_pathway?hsa00380+15" } } } } } , 13688 { 13689 type generif , 13690 text "Data suggest that the -263G/C single nucleotide polymorphism of 13691 arylalkylamine-N-acetyl-transferase (AA-NAT) may be an important determinant 13692 of the late/short sleep pattern." , 13693 version 0 , 13694 refs { 13695 pmid 15332344 } , 13696 create-date 13697 str "Sep 27 2004 4:34PM" , 13698 update-date 13699 str "Sep 27 2004 7:00PM" } , 13700 { 13701 type generif , 13702 text "There is a significant increase in AANAT allele positivity at the 13703 single nucleotide polymorphism (alanine 129--> threonine) at between patients 13704 with DSPS & controls. AA-NAT could be a susceptibility gene for DSPS." , 13705 version 0 , 13706 refs { 13707 pmid 12736803 } , 13708 create-date 13709 str "Jul 10 2003 12:00AM" , 13710 update-date 13711 str "May 30 2004 7:11AM" } } , 13712 unique-keys { 13713 { 13714 db "LocusID" , 13715 tag 13716 id 15 } , 13717 { 13718 db "MIM" , 13719 tag 13720 id 600950 } } , 13721 xtra-index-terms { 13722 "LOC15" } } 13723Entrezgene ::= { 13724 track-info { 13725 geneid 9996 , 13726 status secondary , 13727 current-id { 13728 { 13729 db "LocusID" , 13730 tag 13731 id 320632 } , 13732 { 13733 db "GeneID" , 13734 tag 13735 id 320632 } } , 13736 create-date 13737 std { 13738 year 2003 , 13739 month 8 , 13740 day 28 , 13741 hour 21 , 13742 minute 39 , 13743 second 0 } , 13744 update-date 13745 std { 13746 year 2005 , 13747 month 2 , 13748 day 17 , 13749 hour 12 , 13750 minute 54 , 13751 second 0 } } , 13752 type protein-coding , 13753 source { 13754 genome genomic , 13755 origin natural , 13756 org { 13757 taxname "Mus musculus" , 13758 common "house mouse" , 13759 db { 13760 { 13761 db "taxon" , 13762 tag 13763 id 10090 } } , 13764 syn { 13765 "mouse" } , 13766 orgname { 13767 name 13768 binomial { 13769 genus "Mus" , 13770 species "musculus" } , 13771 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 13772 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 13773 Sciurognathi; Muridae; Murinae; Mus" , 13774 gcode 1 , 13775 mgcode 2 , 13776 div "ROD" } } } , 13777 gene { 13778 } , 13779 gene-source { 13780 src "LocusLink" , 13781 src-int 9996 , 13782 src-str2 "9996" , 13783 gene-display FALSE , 13784 locus-display FALSE , 13785 extra-terms FALSE } , 13786 locus { 13787 { 13788 type genomic , 13789 version 0 } } , 13790 unique-keys { 13791 { 13792 db "LocusID" , 13793 tag 13794 id 9996 } } , 13795 xtra-index-terms { 13796 "LOC320632" } } 13797Entrezgene ::= { 13798 track-info { 13799 geneid 11286 , 13800 status secondary , 13801 current-id { 13802 { 13803 db "LocusID" , 13804 tag 13805 id 50518 } , 13806 { 13807 db "GeneID" , 13808 tag 13809 id 50518 } } , 13810 create-date 13811 std { 13812 year 2003 , 13813 month 8 , 13814 day 28 , 13815 hour 21 , 13816 minute 39 , 13817 second 0 } , 13818 update-date 13819 std { 13820 year 2005 , 13821 month 2 , 13822 day 17 , 13823 hour 12 , 13824 minute 54 , 13825 second 0 } } , 13826 type unknown , 13827 source { 13828 genome genomic , 13829 origin natural , 13830 org { 13831 taxname "Mus musculus" , 13832 common "house mouse" , 13833 db { 13834 { 13835 db "taxon" , 13836 tag 13837 id 10090 } } , 13838 syn { 13839 "mouse" } , 13840 orgname { 13841 name 13842 binomial { 13843 genus "Mus" , 13844 species "musculus" } , 13845 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 13846 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 13847 Sciurognathi; Muridae; Murinae; Mus" , 13848 gcode 1 , 13849 mgcode 2 , 13850 div "ROD" } } } , 13851 gene { 13852 } , 13853 gene-source { 13854 src "LocusLink" , 13855 src-int 11286 , 13856 src-str2 "11286" , 13857 gene-display FALSE , 13858 locus-display FALSE , 13859 extra-terms FALSE } , 13860 locus { 13861 { 13862 type genomic , 13863 version 0 } } , 13864 properties { 13865 { 13866 type property , 13867 label "Property" , 13868 text "phenotype only" , 13869 version 0 } } , 13870 unique-keys { 13871 { 13872 db "LocusID" , 13873 tag 13874 id 11286 } } , 13875 xtra-index-terms { 13876 "LOC50518" } , 13877 xtra-properties { 13878 { 13879 tag "PROP" , 13880 value "phenotype only" } } } 13881Entrezgene ::= { 13882 track-info { 13883 geneid 11287 , 13884 status live , 13885 create-date 13886 std { 13887 year 2003 , 13888 month 8 , 13889 day 28 , 13890 hour 21 , 13891 minute 39 , 13892 second 0 } , 13893 update-date 13894 std { 13895 year 2005 , 13896 month 4 , 13897 day 19 , 13898 hour 12 , 13899 minute 12 , 13900 second 0 } } , 13901 type protein-coding , 13902 source { 13903 genome genomic , 13904 origin natural , 13905 org { 13906 taxname "Mus musculus" , 13907 common "house mouse" , 13908 db { 13909 { 13910 db "taxon" , 13911 tag 13912 id 10090 } } , 13913 syn { 13914 "mouse" } , 13915 orgname { 13916 name 13917 binomial { 13918 genus "Mus" , 13919 species "musculus" } , 13920 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 13921 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 13922 Sciurognathi; Muridae; Murinae; Mus" , 13923 gcode 1 , 13924 mgcode 2 , 13925 div "ROD" } } , 13926 subtype { 13927 { 13928 subtype chromosome , 13929 name "6" } } } , 13930 gene { 13931 locus "Pzp" , 13932 desc "pregnancy zone protein" , 13933 maploc "6 62.0 cM" , 13934 syn { 13935 "A1m" , 13936 "A2m" , 13937 "MAM" } , 13938 locus-tag "MGI:87854" } , 13939 prot { 13940 name { 13941 "pregnancy zone protein" , 13942 "alpha 1 macroglobulin" } } , 13943 location { 13944 { 13945 display-str "6 F1-G3" , 13946 method 13947 map-type cyto } , 13948 { 13949 display-str "6 62.0 cM" , 13950 method 13951 map-type cM } } , 13952 gene-source { 13953 src "LocusLink" , 13954 src-int 11287 , 13955 src-str2 "11287" , 13956 gene-display FALSE , 13957 locus-display FALSE , 13958 extra-terms FALSE } , 13959 locus { 13960 { 13961 type genomic , 13962 heading "Reference" , 13963 accession "NC_000072" , 13964 version 1 , 13965 seqs { 13966 int { 13967 from 129138521 , 13968 to 129181660 , 13969 strand minus , 13970 id 13971 gi 51863714 } } , 13972 products { 13973 { 13974 type mRNA , 13975 heading "Reference" , 13976 accession "NM_007376" , 13977 version 1 , 13978 genomic-coords { 13979 mix { 13980 int { 13981 from 129138521 , 13982 to 129138673 , 13983 strand minus , 13984 id 13985 gi 51863714 } , 13986 int { 13987 from 129139811 , 13988 to 129139852 , 13989 strand minus , 13990 id 13991 gi 51863714 } , 13992 int { 13993 from 129140505 , 13994 to 129140607 , 13995 strand minus , 13996 id 13997 gi 51863714 } , 13998 int { 13999 from 129141065 , 14000 to 129141133 , 14001 strand minus , 14002 id 14003 gi 51863714 } , 14004 int { 14005 from 129141840 , 14006 to 129141930 , 14007 strand minus , 14008 id 14009 gi 51863714 } , 14010 int { 14011 from 129142350 , 14012 to 129142480 , 14013 strand minus , 14014 id 14015 gi 51863714 } , 14016 int { 14017 from 129142828 , 14018 to 129143046 , 14019 strand minus , 14020 id 14021 gi 51863714 } , 14022 int { 14023 from 129143853 , 14024 to 129144094 , 14025 strand minus , 14026 id 14027 gi 51863714 } , 14028 int { 14029 from 129144629 , 14030 to 129144806 , 14031 strand minus , 14032 id 14033 gi 51863714 } , 14034 int { 14035 from 129144966 , 14036 to 129145040 , 14037 strand minus , 14038 id 14039 gi 51863714 } , 14040 int { 14041 from 129145470 , 14042 to 129145626 , 14043 strand minus , 14044 id 14045 gi 51863714 } , 14046 int { 14047 from 129146112 , 14048 to 129146202 , 14049 strand minus , 14050 id 14051 gi 51863714 } , 14052 int { 14053 from 129146443 , 14054 to 129146619 , 14055 strand minus , 14056 id 14057 gi 51863714 } , 14058 int { 14059 from 129147104 , 14060 to 129147187 , 14061 strand minus , 14062 id 14063 gi 51863714 } , 14064 int { 14065 from 129149375 , 14066 to 129149426 , 14067 strand minus , 14068 id 14069 gi 51863714 } , 14070 int { 14071 from 129149655 , 14072 to 129149776 , 14073 strand minus , 14074 id 14075 gi 51863714 } , 14076 int { 14077 from 129150140 , 14078 to 129150266 , 14079 strand minus , 14080 id 14081 gi 51863714 } , 14082 int { 14083 from 129150847 , 14084 to 129151075 , 14085 strand minus , 14086 id 14087 gi 51863714 } , 14088 int { 14089 from 129151526 , 14090 to 129151700 , 14091 strand minus , 14092 id 14093 gi 51863714 } , 14094 int { 14095 from 129153906 , 14096 to 129153993 , 14097 strand minus , 14098 id 14099 gi 51863714 } , 14100 int { 14101 from 129157123 , 14102 to 129157287 , 14103 strand minus , 14104 id 14105 gi 51863714 } , 14106 int { 14107 from 129158420 , 14108 to 129158569 , 14109 strand minus , 14110 id 14111 gi 51863714 } , 14112 int { 14113 from 129161683 , 14114 to 129161825 , 14115 strand minus , 14116 id 14117 gi 51863714 } , 14118 int { 14119 from 129165292 , 14120 to 129165355 , 14121 strand minus , 14122 id 14123 gi 51863714 } , 14124 int { 14125 from 129167103 , 14126 to 129167330 , 14127 strand minus , 14128 id 14129 gi 51863714 } , 14130 int { 14131 from 129168683 , 14132 to 129168844 , 14133 strand minus , 14134 id 14135 gi 51863714 } , 14136 int { 14137 from 129171020 , 14138 to 129171129 , 14139 strand minus , 14140 id 14141 gi 51863714 } , 14142 int { 14143 from 129171763 , 14144 to 129171877 , 14145 strand minus , 14146 id 14147 gi 51863714 } , 14148 int { 14149 from 129174339 , 14150 to 129174462 , 14151 strand minus , 14152 id 14153 gi 51863714 } , 14154 int { 14155 from 129176048 , 14156 to 129176132 , 14157 strand minus , 14158 id 14159 gi 51863714 } , 14160 int { 14161 from 129176963 , 14162 to 129177131 , 14163 strand minus , 14164 id 14165 gi 51863714 } , 14166 int { 14167 from 129177687 , 14168 to 129177707 , 14169 strand minus , 14170 id 14171 gi 51863714 } , 14172 int { 14173 from 129178724 , 14174 to 129178776 , 14175 strand minus , 14176 id 14177 gi 51863714 } , 14178 int { 14179 from 129178917 , 14180 to 129179070 , 14181 strand minus , 14182 id 14183 gi 51863714 } , 14184 int { 14185 from 129180062 , 14186 to 129180245 , 14187 strand minus , 14188 id 14189 gi 51863714 } , 14190 int { 14191 from 129181526 , 14192 to 129181660 , 14193 strand minus , 14194 id 14195 gi 51863714 } } } , 14196 seqs { 14197 whole 14198 gi 6680607 } , 14199 products { 14200 { 14201 type peptide , 14202 heading "Reference" , 14203 accession "NP_031402" , 14204 version 1 , 14205 genomic-coords { 14206 packed-int { 14207 { 14208 from 129138651 , 14209 to 129138673 , 14210 strand minus , 14211 id 14212 gi 51863714 } , 14213 { 14214 from 129139811 , 14215 to 129139852 , 14216 strand minus , 14217 id 14218 gi 51863714 } , 14219 { 14220 from 129140505 , 14221 to 129140607 , 14222 strand minus , 14223 id 14224 gi 51863714 } , 14225 { 14226 from 129141065 , 14227 to 129141133 , 14228 strand minus , 14229 id 14230 gi 51863714 } , 14231 { 14232 from 129141840 , 14233 to 129141930 , 14234 strand minus , 14235 id 14236 gi 51863714 } , 14237 { 14238 from 129142350 , 14239 to 129142480 , 14240 strand minus , 14241 id 14242 gi 51863714 } , 14243 { 14244 from 129142828 , 14245 to 129143046 , 14246 strand minus , 14247 id 14248 gi 51863714 } , 14249 { 14250 from 129143853 , 14251 to 129144094 , 14252 strand minus , 14253 id 14254 gi 51863714 } , 14255 { 14256 from 129144629 , 14257 to 129144806 , 14258 strand minus , 14259 id 14260 gi 51863714 } , 14261 { 14262 from 129144966 , 14263 to 129145040 , 14264 strand minus , 14265 id 14266 gi 51863714 } , 14267 { 14268 from 129145470 , 14269 to 129145626 , 14270 strand minus , 14271 id 14272 gi 51863714 } , 14273 { 14274 from 129146112 , 14275 to 129146202 , 14276 strand minus , 14277 id 14278 gi 51863714 } , 14279 { 14280 from 129146443 , 14281 to 129146619 , 14282 strand minus , 14283 id 14284 gi 51863714 } , 14285 { 14286 from 129147104 , 14287 to 129147187 , 14288 strand minus , 14289 id 14290 gi 51863714 } , 14291 { 14292 from 129149375 , 14293 to 129149426 , 14294 strand minus , 14295 id 14296 gi 51863714 } , 14297 { 14298 from 129149655 , 14299 to 129149776 , 14300 strand minus , 14301 id 14302 gi 51863714 } , 14303 { 14304 from 129150140 , 14305 to 129150266 , 14306 strand minus , 14307 id 14308 gi 51863714 } , 14309 { 14310 from 129150847 , 14311 to 129151075 , 14312 strand minus , 14313 id 14314 gi 51863714 } , 14315 { 14316 from 129151526 , 14317 to 129151700 , 14318 strand minus , 14319 id 14320 gi 51863714 } , 14321 { 14322 from 129153906 , 14323 to 129153993 , 14324 strand minus , 14325 id 14326 gi 51863714 } , 14327 { 14328 from 129157123 , 14329 to 129157287 , 14330 strand minus , 14331 id 14332 gi 51863714 } , 14333 { 14334 from 129158420 , 14335 to 129158569 , 14336 strand minus , 14337 id 14338 gi 51863714 } , 14339 { 14340 from 129161683 , 14341 to 129161825 , 14342 strand minus , 14343 id 14344 gi 51863714 } , 14345 { 14346 from 129165292 , 14347 to 129165355 , 14348 strand minus , 14349 id 14350 gi 51863714 } , 14351 { 14352 from 129167103 , 14353 to 129167330 , 14354 strand minus , 14355 id 14356 gi 51863714 } , 14357 { 14358 from 129168683 , 14359 to 129168844 , 14360 strand minus , 14361 id 14362 gi 51863714 } , 14363 { 14364 from 129171020 , 14365 to 129171129 , 14366 strand minus , 14367 id 14368 gi 51863714 } , 14369 { 14370 from 129171763 , 14371 to 129171877 , 14372 strand minus , 14373 id 14374 gi 51863714 } , 14375 { 14376 from 129174339 , 14377 to 129174462 , 14378 strand minus , 14379 id 14380 gi 51863714 } , 14381 { 14382 from 129176048 , 14383 to 129176132 , 14384 strand minus , 14385 id 14386 gi 51863714 } , 14387 { 14388 from 129176963 , 14389 to 129177131 , 14390 strand minus , 14391 id 14392 gi 51863714 } , 14393 { 14394 from 129177687 , 14395 to 129177707 , 14396 strand minus , 14397 id 14398 gi 51863714 } , 14399 { 14400 from 129178724 , 14401 to 129178776 , 14402 strand minus , 14403 id 14404 gi 51863714 } , 14405 { 14406 from 129178917 , 14407 to 129179070 , 14408 strand minus , 14409 id 14410 gi 51863714 } , 14411 { 14412 from 129180062 , 14413 to 129180245 , 14414 strand minus , 14415 id 14416 gi 51863714 } , 14417 { 14418 from 129181526 , 14419 to 129181611 , 14420 strand minus , 14421 id 14422 gi 51863714 } } } , 14423 seqs { 14424 whole 14425 gi 6680608 } } } } } } , 14426 { 14427 type genomic , 14428 heading "Reference" , 14429 accession "NT_039356" , 14430 version 3 , 14431 seqs { 14432 int { 14433 from 3999237 , 14434 to 4042376 , 14435 strand minus , 14436 id 14437 gi 51712708 } } , 14438 products { 14439 { 14440 type mRNA , 14441 heading "Reference" , 14442 accession "NM_007376" , 14443 version 1 , 14444 genomic-coords { 14445 mix { 14446 int { 14447 from 3999237 , 14448 to 3999389 , 14449 strand minus , 14450 id 14451 gi 51712708 } , 14452 int { 14453 from 4000527 , 14454 to 4000568 , 14455 strand minus , 14456 id 14457 gi 51712708 } , 14458 int { 14459 from 4001221 , 14460 to 4001323 , 14461 strand minus , 14462 id 14463 gi 51712708 } , 14464 int { 14465 from 4001781 , 14466 to 4001849 , 14467 strand minus , 14468 id 14469 gi 51712708 } , 14470 int { 14471 from 4002556 , 14472 to 4002646 , 14473 strand minus , 14474 id 14475 gi 51712708 } , 14476 int { 14477 from 4003066 , 14478 to 4003196 , 14479 strand minus , 14480 id 14481 gi 51712708 } , 14482 int { 14483 from 4003544 , 14484 to 4003762 , 14485 strand minus , 14486 id 14487 gi 51712708 } , 14488 int { 14489 from 4004569 , 14490 to 4004810 , 14491 strand minus , 14492 id 14493 gi 51712708 } , 14494 int { 14495 from 4005345 , 14496 to 4005522 , 14497 strand minus , 14498 id 14499 gi 51712708 } , 14500 int { 14501 from 4005682 , 14502 to 4005756 , 14503 strand minus , 14504 id 14505 gi 51712708 } , 14506 int { 14507 from 4006186 , 14508 to 4006342 , 14509 strand minus , 14510 id 14511 gi 51712708 } , 14512 int { 14513 from 4006828 , 14514 to 4006918 , 14515 strand minus , 14516 id 14517 gi 51712708 } , 14518 int { 14519 from 4007159 , 14520 to 4007335 , 14521 strand minus , 14522 id 14523 gi 51712708 } , 14524 int { 14525 from 4007820 , 14526 to 4007903 , 14527 strand minus , 14528 id 14529 gi 51712708 } , 14530 int { 14531 from 4010091 , 14532 to 4010142 , 14533 strand minus , 14534 id 14535 gi 51712708 } , 14536 int { 14537 from 4010371 , 14538 to 4010492 , 14539 strand minus , 14540 id 14541 gi 51712708 } , 14542 int { 14543 from 4010856 , 14544 to 4010982 , 14545 strand minus , 14546 id 14547 gi 51712708 } , 14548 int { 14549 from 4011563 , 14550 to 4011791 , 14551 strand minus , 14552 id 14553 gi 51712708 } , 14554 int { 14555 from 4012242 , 14556 to 4012416 , 14557 strand minus , 14558 id 14559 gi 51712708 } , 14560 int { 14561 from 4014622 , 14562 to 4014709 , 14563 strand minus , 14564 id 14565 gi 51712708 } , 14566 int { 14567 from 4017839 , 14568 to 4018003 , 14569 strand minus , 14570 id 14571 gi 51712708 } , 14572 int { 14573 from 4019136 , 14574 to 4019285 , 14575 strand minus , 14576 id 14577 gi 51712708 } , 14578 int { 14579 from 4022399 , 14580 to 4022541 , 14581 strand minus , 14582 id 14583 gi 51712708 } , 14584 int { 14585 from 4026008 , 14586 to 4026071 , 14587 strand minus , 14588 id 14589 gi 51712708 } , 14590 int { 14591 from 4027819 , 14592 to 4028046 , 14593 strand minus , 14594 id 14595 gi 51712708 } , 14596 int { 14597 from 4029399 , 14598 to 4029560 , 14599 strand minus , 14600 id 14601 gi 51712708 } , 14602 int { 14603 from 4031736 , 14604 to 4031845 , 14605 strand minus , 14606 id 14607 gi 51712708 } , 14608 int { 14609 from 4032479 , 14610 to 4032593 , 14611 strand minus , 14612 id 14613 gi 51712708 } , 14614 int { 14615 from 4035055 , 14616 to 4035178 , 14617 strand minus , 14618 id 14619 gi 51712708 } , 14620 int { 14621 from 4036764 , 14622 to 4036848 , 14623 strand minus , 14624 id 14625 gi 51712708 } , 14626 int { 14627 from 4037679 , 14628 to 4037847 , 14629 strand minus , 14630 id 14631 gi 51712708 } , 14632 int { 14633 from 4038403 , 14634 to 4038423 , 14635 strand minus , 14636 id 14637 gi 51712708 } , 14638 int { 14639 from 4039440 , 14640 to 4039492 , 14641 strand minus , 14642 id 14643 gi 51712708 } , 14644 int { 14645 from 4039633 , 14646 to 4039786 , 14647 strand minus , 14648 id 14649 gi 51712708 } , 14650 int { 14651 from 4040778 , 14652 to 4040961 , 14653 strand minus , 14654 id 14655 gi 51712708 } , 14656 int { 14657 from 4042242 , 14658 to 4042376 , 14659 strand minus , 14660 id 14661 gi 51712708 } } } , 14662 seqs { 14663 whole 14664 gi 6680607 } , 14665 products { 14666 { 14667 type peptide , 14668 heading "Reference" , 14669 accession "NP_031402" , 14670 version 1 , 14671 genomic-coords { 14672 packed-int { 14673 { 14674 from 3999367 , 14675 to 3999389 , 14676 strand minus , 14677 id 14678 gi 51712708 } , 14679 { 14680 from 4000527 , 14681 to 4000568 , 14682 strand minus , 14683 id 14684 gi 51712708 } , 14685 { 14686 from 4001221 , 14687 to 4001323 , 14688 strand minus , 14689 id 14690 gi 51712708 } , 14691 { 14692 from 4001781 , 14693 to 4001849 , 14694 strand minus , 14695 id 14696 gi 51712708 } , 14697 { 14698 from 4002556 , 14699 to 4002646 , 14700 strand minus , 14701 id 14702 gi 51712708 } , 14703 { 14704 from 4003066 , 14705 to 4003196 , 14706 strand minus , 14707 id 14708 gi 51712708 } , 14709 { 14710 from 4003544 , 14711 to 4003762 , 14712 strand minus , 14713 id 14714 gi 51712708 } , 14715 { 14716 from 4004569 , 14717 to 4004810 , 14718 strand minus , 14719 id 14720 gi 51712708 } , 14721 { 14722 from 4005345 , 14723 to 4005522 , 14724 strand minus , 14725 id 14726 gi 51712708 } , 14727 { 14728 from 4005682 , 14729 to 4005756 , 14730 strand minus , 14731 id 14732 gi 51712708 } , 14733 { 14734 from 4006186 , 14735 to 4006342 , 14736 strand minus , 14737 id 14738 gi 51712708 } , 14739 { 14740 from 4006828 , 14741 to 4006918 , 14742 strand minus , 14743 id 14744 gi 51712708 } , 14745 { 14746 from 4007159 , 14747 to 4007335 , 14748 strand minus , 14749 id 14750 gi 51712708 } , 14751 { 14752 from 4007820 , 14753 to 4007903 , 14754 strand minus , 14755 id 14756 gi 51712708 } , 14757 { 14758 from 4010091 , 14759 to 4010142 , 14760 strand minus , 14761 id 14762 gi 51712708 } , 14763 { 14764 from 4010371 , 14765 to 4010492 , 14766 strand minus , 14767 id 14768 gi 51712708 } , 14769 { 14770 from 4010856 , 14771 to 4010982 , 14772 strand minus , 14773 id 14774 gi 51712708 } , 14775 { 14776 from 4011563 , 14777 to 4011791 , 14778 strand minus , 14779 id 14780 gi 51712708 } , 14781 { 14782 from 4012242 , 14783 to 4012416 , 14784 strand minus , 14785 id 14786 gi 51712708 } , 14787 { 14788 from 4014622 , 14789 to 4014709 , 14790 strand minus , 14791 id 14792 gi 51712708 } , 14793 { 14794 from 4017839 , 14795 to 4018003 , 14796 strand minus , 14797 id 14798 gi 51712708 } , 14799 { 14800 from 4019136 , 14801 to 4019285 , 14802 strand minus , 14803 id 14804 gi 51712708 } , 14805 { 14806 from 4022399 , 14807 to 4022541 , 14808 strand minus , 14809 id 14810 gi 51712708 } , 14811 { 14812 from 4026008 , 14813 to 4026071 , 14814 strand minus , 14815 id 14816 gi 51712708 } , 14817 { 14818 from 4027819 , 14819 to 4028046 , 14820 strand minus , 14821 id 14822 gi 51712708 } , 14823 { 14824 from 4029399 , 14825 to 4029560 , 14826 strand minus , 14827 id 14828 gi 51712708 } , 14829 { 14830 from 4031736 , 14831 to 4031845 , 14832 strand minus , 14833 id 14834 gi 51712708 } , 14835 { 14836 from 4032479 , 14837 to 4032593 , 14838 strand minus , 14839 id 14840 gi 51712708 } , 14841 { 14842 from 4035055 , 14843 to 4035178 , 14844 strand minus , 14845 id 14846 gi 51712708 } , 14847 { 14848 from 4036764 , 14849 to 4036848 , 14850 strand minus , 14851 id 14852 gi 51712708 } , 14853 { 14854 from 4037679 , 14855 to 4037847 , 14856 strand minus , 14857 id 14858 gi 51712708 } , 14859 { 14860 from 4038403 , 14861 to 4038423 , 14862 strand minus , 14863 id 14864 gi 51712708 } , 14865 { 14866 from 4039440 , 14867 to 4039492 , 14868 strand minus , 14869 id 14870 gi 51712708 } , 14871 { 14872 from 4039633 , 14873 to 4039786 , 14874 strand minus , 14875 id 14876 gi 51712708 } , 14877 { 14878 from 4040778 , 14879 to 4040961 , 14880 strand minus , 14881 id 14882 gi 51712708 } , 14883 { 14884 from 4042242 , 14885 to 4042327 , 14886 strand minus , 14887 id 14888 gi 51712708 } } } , 14889 seqs { 14890 whole 14891 gi 6680608 } } } } } } } , 14892 properties { 14893 { 14894 type comment , 14895 label "Nomenclature" , 14896 version 0 , 14897 source { 14898 { 14899 anchor "Mouse Genome Informatics" } } , 14900 properties { 14901 { 14902 type property , 14903 label "Official Symbol" , 14904 text "Pzp" , 14905 version 0 } , 14906 { 14907 type property , 14908 label "Official Full Name" , 14909 text "pregnancy zone protein" , 14910 version 0 } } } , 14911 { 14912 type comment , 14913 heading "GeneOntology" , 14914 version 0 , 14915 source { 14916 { 14917 pre-text "Provided by" , 14918 anchor "MGI" , 14919 url "http://www.informatics.jax.org/" } } , 14920 comment { 14921 { 14922 type comment , 14923 label "Function" , 14924 version 0 , 14925 comment { 14926 { 14927 type comment , 14928 version 0 , 14929 refs { 14930 pmid 5559967 } , 14931 source { 14932 { 14933 src { 14934 db "GO" , 14935 tag 14936 id 4866 } , 14937 anchor "endopeptidase inhibitor activity" , 14938 post-text "evidence: IDA" } } } , 14939 { 14940 type comment , 14941 version 0 , 14942 source { 14943 { 14944 src { 14945 db "GO" , 14946 tag 14947 id 4867 } , 14948 anchor "serine-type endopeptidase inhibitor activity" , 14949 post-text "evidence: IEA" } } } , 14950 { 14951 type comment , 14952 version 0 , 14953 source { 14954 { 14955 src { 14956 db "GO" , 14957 tag 14958 id 17114 } , 14959 anchor "wide-spectrum protease inhibitor activity" , 14960 post-text "evidence: IEA" } } } } } , 14961 { 14962 type comment , 14963 label "Component" , 14964 version 0 , 14965 comment { 14966 { 14967 type comment , 14968 version 0 , 14969 refs { 14970 pmid 5559967 } , 14971 source { 14972 { 14973 src { 14974 db "GO" , 14975 tag 14976 id 5576 } , 14977 anchor "extracellular region" , 14978 post-text "evidence: TAS" } } } , 14979 { 14980 type comment , 14981 version 0 , 14982 refs { 14983 pmid 12466851 } , 14984 source { 14985 { 14986 src { 14987 db "GO" , 14988 tag 14989 id 5615 } , 14990 anchor "extracellular space" , 14991 post-text "evidence: TAS" } } } } } } } } , 14992 homology { 14993 { 14994 type comment , 14995 heading "Rat" , 14996 version 0 , 14997 source { 14998 { 14999 src { 15000 db "HomoloGene" , 15001 tag 15002 id 56378 } , 15003 anchor "Map Viewer" , 15004 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=6& 15005MAPS=genes-r-org/rat-chr/mouse%3A6,genes-r-org/mouse-chr6&query=e%3A11287[id]+ 15006AND+gene[obj_type]&QSTR=pzp&cmd=focus&fill=10" } } } } , 15007 comments { 15008 { 15009 type comment , 15010 heading "LocusTagLink" , 15011 version 0 , 15012 source { 15013 { 15014 src { 15015 db "MGI" , 15016 tag 15017 id 87854 } } } } , 15018 { 15019 type comment , 15020 heading "RefSeq Status" , 15021 label "PROVISIONAL" , 15022 version 0 } , 15023 { 15024 type comment , 15025 version 0 , 15026 refs { 15027 pmid 12477932 , 15028 pmid 12466851 , 15029 pmid 7528166 , 15030 pmid 5559967 , 15031 pmid 1280217 } } , 15032 { 15033 type comment , 15034 heading "Markers (Sequence Tagged Sites/STS)" , 15035 version 0 , 15036 comment { 15037 { 15038 type comment , 15039 version 0 , 15040 source { 15041 { 15042 src { 15043 db "UniSTS" , 15044 tag 15045 id 140992 } , 15046 anchor "A2m" , 15047 post-text "(e-PCR)" } } , 15048 comment { 15049 { 15050 type other , 15051 label "Alternate name" , 15052 text "D6Uwa7" , 15053 version 0 } , 15054 { 15055 type other , 15056 label "Alternate name" , 15057 text "MGI:893149" , 15058 version 0 } , 15059 { 15060 type other , 15061 label "Alternate name" , 15062 text "Pzp" , 15063 version 0 } } } , 15064 { 15065 type comment , 15066 version 0 , 15067 source { 15068 { 15069 src { 15070 db "UniSTS" , 15071 tag 15072 id 179416 } , 15073 anchor "AI838740" , 15074 post-text "(e-PCR)" } } , 15075 comment { 15076 { 15077 type other , 15078 label "Alternate name" , 15079 text "659717" , 15080 version 0 } } } , 15081 { 15082 type comment , 15083 version 0 , 15084 source { 15085 { 15086 src { 15087 db "UniSTS" , 15088 tag 15089 id 179477 } , 15090 anchor "AI893533" , 15091 post-text "(e-PCR)" } } , 15092 comment { 15093 { 15094 type other , 15095 label "Alternate name" , 15096 text "681710" , 15097 version 0 } } } } } , 15098 { 15099 type comment , 15100 heading "NCBI Reference Sequences (RefSeq)" , 15101 version 0 , 15102 products { 15103 { 15104 type mRNA , 15105 heading "mRNA Sequence" , 15106 accession "NM_007376" , 15107 version 1 , 15108 source { 15109 { 15110 src { 15111 db "Nucleotide" , 15112 tag 15113 id 6680607 } , 15114 anchor "NM_007376" } } , 15115 seqs { 15116 whole 15117 gi 6680607 } , 15118 products { 15119 { 15120 type peptide , 15121 heading "Product" , 15122 accession "NP_031402" , 15123 version 1 , 15124 source { 15125 { 15126 src { 15127 db "Protein" , 15128 tag 15129 id 6680608 } , 15130 anchor "NP_031402" , 15131 post-text "pregnancy zone protein" } } , 15132 seqs { 15133 whole 15134 gi 6680608 } , 15135 comment { 15136 { 15137 type other , 15138 heading "Conserved Domains" , 15139 version 0 , 15140 source { 15141 { 15142 src { 15143 db "PROT_CDD" , 15144 tag 15145 id 6680608 } , 15146 pre-text "(2)" , 15147 anchor "summary" } } , 15148 comment { 15149 { 15150 type other , 15151 version 0 , 15152 source { 15153 { 15154 src { 15155 db "CDD" , 15156 tag 15157 id 5952 } , 15158 anchor "pfam00207: A2M; Alpha-2-macroglobulin family" } } , 15159 comment { 15160 { 15161 type other , 15162 text "Location: 738 - 1482 Blast Score: 1820" , 15163 version 0 } } } , 15164 { 15165 type other , 15166 version 0 , 15167 source { 15168 { 15169 src { 15170 db "CDD" , 15171 tag 15172 id 25832 } , 15173 anchor "pfam01835: A2M_N; Alpha-2-macroglobulin 15174 family N-terminal region" } } , 15175 comment { 15176 { 15177 type other , 15178 text "Location: 22 - 622 Blast Score: 1231" , 15179 version 0 } } } } } } } } , 15180 comment { 15181 { 15182 type other , 15183 heading "Source Sequence" , 15184 version 0 , 15185 source { 15186 { 15187 src { 15188 db "Nucleotide" , 15189 tag 15190 str "M93264" } , 15191 anchor "M93264" } } , 15192 comment { 15193 { 15194 type other , 15195 version 0 } } } } } } } , 15196 { 15197 type comment , 15198 heading "Related Sequences" , 15199 version 0 , 15200 products { 15201 { 15202 type genomic , 15203 heading "Genomic" , 15204 accession "U06977" , 15205 version 1 , 15206 source { 15207 { 15208 src { 15209 db "Nucleotide" , 15210 tag 15211 id 463883 } , 15212 anchor "U06977" } } , 15213 seqs { 15214 whole 15215 gi 463883 } , 15216 products { 15217 { 15218 type peptide , 15219 accession "AAA87890" , 15220 version 1 , 15221 source { 15222 { 15223 src { 15224 db "Protein" , 15225 tag 15226 id 463884 } , 15227 anchor "AAA87890" } } , 15228 seqs { 15229 whole 15230 gi 463884 } } } } , 15231 { 15232 type mRNA , 15233 heading "mRNA" , 15234 accession "BC057983" , 15235 version 1 , 15236 source { 15237 { 15238 src { 15239 db "Nucleotide" , 15240 tag 15241 id 34785995 } , 15242 anchor "BC057983" } } , 15243 seqs { 15244 whole 15245 gi 34785995 } , 15246 products { 15247 { 15248 type peptide , 15249 accession "AAH57983" , 15250 version 1 , 15251 source { 15252 { 15253 src { 15254 db "Protein" , 15255 tag 15256 id 34785996 } , 15257 anchor "AAH57983" } } , 15258 seqs { 15259 whole 15260 gi 34785996 } } } , 15261 comment { 15262 { 15263 type other , 15264 label "Strain" , 15265 text "FVB/N" , 15266 version 0 } } } , 15267 { 15268 type mRNA , 15269 heading "mRNA" , 15270 accession "M93264" , 15271 version 1 , 15272 source { 15273 { 15274 src { 15275 db "Nucleotide" , 15276 tag 15277 id 199085 } , 15278 anchor "M93264" } } , 15279 seqs { 15280 whole 15281 gi 199085 } , 15282 products { 15283 { 15284 type peptide , 15285 accession "AAA39508" , 15286 version 1 , 15287 source { 15288 { 15289 src { 15290 db "Protein" , 15291 tag 15292 id 199086 } , 15293 anchor "AAA39508" } } , 15294 seqs { 15295 whole 15296 gi 199086 } } } } , 15297 { 15298 type other , 15299 text "None" , 15300 version 0 , 15301 products { 15302 { 15303 type peptide , 15304 accession "Q61838" , 15305 version 0 , 15306 source { 15307 { 15308 src { 15309 db "Protein" , 15310 tag 15311 id 2492496 } , 15312 anchor "Q61838" } } , 15313 seqs { 15314 whole 15315 gi 2492496 } } } } } } , 15316 { 15317 type comment , 15318 heading "Additional Links" , 15319 version 0 , 15320 comment { 15321 { 15322 type comment , 15323 version 0 , 15324 source { 15325 { 15326 src { 15327 db "Evidence Viewer" , 15328 tag 15329 str "11287" } , 15330 anchor "Evidence Viewer" , 15331 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont 15332ig=NT_039356.3&gene=Pzp&lid=11287&from=3999238&to=4042377" } } } , 15333 { 15334 type comment , 15335 version 0 , 15336 source { 15337 { 15338 src { 15339 db "ModelMaker" , 15340 tag 15341 str "11287" } , 15342 anchor "ModelMaker" , 15343 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10 15344090&contig=NT_039356.3&gene=Pzp&lid=11287" } } } , 15345 { 15346 type comment , 15347 text "UniGene" , 15348 version 0 , 15349 xtra-properties { 15350 { 15351 tag "UNIGENE" , 15352 value "Mm.260144" } } , 15353 source { 15354 { 15355 src { 15356 db "UniGene" , 15357 tag 15358 str "Mm.260144" } , 15359 anchor "Mm.260144" , 15360 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=26 153610144" } } } , 15362 { 15363 type comment , 15364 version 0 , 15365 source { 15366 { 15367 src { 15368 db "HomoloGene" , 15369 tag 15370 str "11287" } , 15371 anchor "HomoloGene" , 15372 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 1537311287[loc]&TAXID=10090" } } } , 15374 { 15375 type comment , 15376 version 0 , 15377 source { 15378 { 15379 src { 15380 db "MGI" , 15381 tag 15382 id 87854 } , 15383 anchor "MGI" , 15384 url "http://www.informatics.jax.org/searches/accession_report.cg 15385i?id=MGI:87854" } } } , 15386 { 15387 type comment , 15388 version 0 , 15389 source { 15390 { 15391 src { 15392 db "Ensembl" , 15393 tag 15394 str "" } , 15395 url "http://www.ensembl.org/Mus_musculus/contigview?geneid=BC057 15396983" } } } , 15397 { 15398 type comment , 15399 version 0 , 15400 source { 15401 { 15402 src { 15403 db "UCSC" , 15404 tag 15405 str "" } , 15406 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position= 15407BC057983" } } } , 15408 { 15409 type comment , 15410 text "Gene Expression Database (GXD) at MGI" , 15411 version 0 , 15412 source { 15413 { 15414 src { 15415 db "Gene Expression Database (GXD) at MGI" , 15416 tag 15417 str "MGI:87854" } , 15418 anchor "MGI:87854" , 15419 url "http://www.informatics.jax.org/searches/expression_report.c 15420gi?id=MGI:87854" } } } , 15421 { 15422 type comment , 15423 version 0 , 15424 source { 15425 { 15426 src { 15427 db "MGC" , 15428 tag 15429 str "BC057983" } , 15430 anchor "MGC" , 15431 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Mm&LIST=BC057983" } } } } } , 15432 { 15433 type comment , 15434 heading "Alleles" , 15435 version 0 , 15436 comment { 15437 { 15438 type comment , 15439 text "The following allele types are documented at Mouse Genome 15440 Informatics" , 15441 version 0 , 15442 source { 15443 { 15444 anchor "(MGI)" , 15445 url "http://www.informatics.jax.org/searches/allele_report.cgi?m 15446arkerID=MGI:87854" } } } , 15447 { 15448 type comment , 15449 heading "Targeted (knock-out) (1)" , 15450 version 0 , 15451 refs { 15452 pmid 7544347 } } } } } , 15453 unique-keys { 15454 { 15455 db "LocusID" , 15456 tag 15457 id 11287 } , 15458 { 15459 db "MGI" , 15460 tag 15461 id 87854 } } , 15462 xtra-index-terms { 15463 "LOC11287" } } 15464Entrezgene ::= { 15465 track-info { 15466 geneid 11288 , 15467 status secondary , 15468 current-id { 15469 { 15470 db "LocusID" , 15471 tag 15472 id 112131 } , 15473 { 15474 db "GeneID" , 15475 tag 15476 id 112131 } } , 15477 create-date 15478 std { 15479 year 2003 , 15480 month 8 , 15481 day 28 , 15482 hour 21 , 15483 minute 39 , 15484 second 0 } , 15485 update-date 15486 std { 15487 year 2005 , 15488 month 2 , 15489 day 17 , 15490 hour 12 , 15491 minute 54 , 15492 second 0 } } , 15493 type unknown , 15494 source { 15495 genome genomic , 15496 origin natural , 15497 org { 15498 taxname "Mus musculus" , 15499 common "house mouse" , 15500 db { 15501 { 15502 db "taxon" , 15503 tag 15504 id 10090 } } , 15505 syn { 15506 "mouse" } , 15507 orgname { 15508 name 15509 binomial { 15510 genus "Mus" , 15511 species "musculus" } , 15512 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 15513 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 15514 Sciurognathi; Muridae; Murinae; Mus" , 15515 gcode 1 , 15516 mgcode 2 , 15517 div "ROD" } } } , 15518 gene { 15519 } , 15520 gene-source { 15521 src "LocusLink" , 15522 src-int 11288 , 15523 src-str2 "11288" , 15524 gene-display FALSE , 15525 locus-display FALSE , 15526 extra-terms FALSE } , 15527 locus { 15528 { 15529 type genomic , 15530 version 0 } } , 15531 properties { 15532 { 15533 type property , 15534 label "Property" , 15535 text "phenotype only" , 15536 version 0 } } , 15537 unique-keys { 15538 { 15539 db "LocusID" , 15540 tag 15541 id 11288 } } , 15542 xtra-index-terms { 15543 "LOC112131" } , 15544 xtra-properties { 15545 { 15546 tag "PROP" , 15547 value "phenotype only" } } } 15548Entrezgene ::= { 15549 track-info { 15550 geneid 11289 , 15551 status secondary , 15552 current-id { 15553 { 15554 db "LocusID" , 15555 tag 15556 id 107417 } , 15557 { 15558 db "GeneID" , 15559 tag 15560 id 107417 } } , 15561 create-date 15562 std { 15563 year 2003 , 15564 month 8 , 15565 day 28 , 15566 hour 21 , 15567 minute 39 , 15568 second 0 } , 15569 update-date 15570 std { 15571 year 2005 , 15572 month 2 , 15573 day 17 , 15574 hour 12 , 15575 minute 54 , 15576 second 0 } } , 15577 type protein-coding , 15578 source { 15579 genome genomic , 15580 origin natural , 15581 org { 15582 taxname "Mus musculus" , 15583 common "house mouse" , 15584 db { 15585 { 15586 db "taxon" , 15587 tag 15588 id 10090 } } , 15589 syn { 15590 "mouse" } , 15591 orgname { 15592 name 15593 binomial { 15594 genus "Mus" , 15595 species "musculus" } , 15596 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 15597 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 15598 Sciurognathi; Muridae; Murinae; Mus" , 15599 gcode 1 , 15600 mgcode 2 , 15601 div "ROD" } } } , 15602 gene { 15603 } , 15604 gene-source { 15605 src "LocusLink" , 15606 src-int 11289 , 15607 src-str2 "11289" , 15608 gene-display FALSE , 15609 locus-display FALSE , 15610 extra-terms FALSE } , 15611 locus { 15612 { 15613 type genomic , 15614 version 0 } } , 15615 unique-keys { 15616 { 15617 db "LocusID" , 15618 tag 15619 id 11289 } } , 15620 xtra-index-terms { 15621 "LOC107417" } } 15622Entrezgene ::= { 15623 track-info { 15624 geneid 11293 , 15625 status secondary , 15626 current-id { 15627 { 15628 db "LocusID" , 15629 tag 15630 id 112132 } , 15631 { 15632 db "GeneID" , 15633 tag 15634 id 112132 } } , 15635 create-date 15636 std { 15637 year 2003 , 15638 month 8 , 15639 day 28 , 15640 hour 21 , 15641 minute 39 , 15642 second 0 } , 15643 update-date 15644 std { 15645 year 2005 , 15646 month 2 , 15647 day 17 , 15648 hour 12 , 15649 minute 54 , 15650 second 0 } } , 15651 type unknown , 15652 source { 15653 genome genomic , 15654 origin natural , 15655 org { 15656 taxname "Mus musculus" , 15657 common "house mouse" , 15658 db { 15659 { 15660 db "taxon" , 15661 tag 15662 id 10090 } } , 15663 syn { 15664 "mouse" } , 15665 orgname { 15666 name 15667 binomial { 15668 genus "Mus" , 15669 species "musculus" } , 15670 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 15671 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 15672 Sciurognathi; Muridae; Murinae; Mus" , 15673 gcode 1 , 15674 mgcode 2 , 15675 div "ROD" } } } , 15676 gene { 15677 } , 15678 gene-source { 15679 src "LocusLink" , 15680 src-int 11293 , 15681 src-str2 "11293" , 15682 gene-display FALSE , 15683 locus-display FALSE , 15684 extra-terms FALSE } , 15685 locus { 15686 { 15687 type genomic , 15688 version 0 } } , 15689 properties { 15690 { 15691 type property , 15692 label "Property" , 15693 text "phenotype only" , 15694 version 0 } } , 15695 unique-keys { 15696 { 15697 db "LocusID" , 15698 tag 15699 id 11293 } } , 15700 xtra-index-terms { 15701 "LOC112132" } , 15702 xtra-properties { 15703 { 15704 tag "PROP" , 15705 value "phenotype only" } } } 15706Entrezgene ::= { 15707 track-info { 15708 geneid 11294 , 15709 status secondary , 15710 current-id { 15711 { 15712 db "LocusID" , 15713 tag 15714 id 109413 } , 15715 { 15716 db "GeneID" , 15717 tag 15718 id 109413 } } , 15719 create-date 15720 std { 15721 year 2003 , 15722 month 8 , 15723 day 28 , 15724 hour 21 , 15725 minute 39 , 15726 second 0 } , 15727 update-date 15728 std { 15729 year 2005 , 15730 month 2 , 15731 day 17 , 15732 hour 12 , 15733 minute 54 , 15734 second 0 } } , 15735 type unknown , 15736 source { 15737 genome genomic , 15738 origin natural , 15739 org { 15740 taxname "Mus musculus" , 15741 common "house mouse" , 15742 db { 15743 { 15744 db "taxon" , 15745 tag 15746 id 10090 } } , 15747 syn { 15748 "mouse" } , 15749 orgname { 15750 name 15751 binomial { 15752 genus "Mus" , 15753 species "musculus" } , 15754 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 15755 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 15756 Sciurognathi; Muridae; Murinae; Mus" , 15757 gcode 1 , 15758 mgcode 2 , 15759 div "ROD" } } } , 15760 gene { 15761 } , 15762 gene-source { 15763 src "LocusLink" , 15764 src-int 11294 , 15765 src-str2 "11294" , 15766 gene-display FALSE , 15767 locus-display FALSE , 15768 extra-terms FALSE } , 15769 locus { 15770 { 15771 type genomic , 15772 version 0 } } , 15773 properties { 15774 { 15775 type property , 15776 label "Property" , 15777 text "phenotype only" , 15778 version 0 } } , 15779 unique-keys { 15780 { 15781 db "LocusID" , 15782 tag 15783 id 11294 } } , 15784 xtra-index-terms { 15785 "LOC109413" } , 15786 xtra-properties { 15787 { 15788 tag "PROP" , 15789 value "phenotype only" } } } 15790Entrezgene ::= { 15791 track-info { 15792 geneid 11295 , 15793 status secondary , 15794 current-id { 15795 { 15796 db "LocusID" , 15797 tag 15798 id 109414 } , 15799 { 15800 db "GeneID" , 15801 tag 15802 id 109414 } } , 15803 create-date 15804 std { 15805 year 2003 , 15806 month 8 , 15807 day 28 , 15808 hour 21 , 15809 minute 39 , 15810 second 0 } , 15811 update-date 15812 std { 15813 year 2005 , 15814 month 2 , 15815 day 17 , 15816 hour 12 , 15817 minute 54 , 15818 second 0 } } , 15819 type unknown , 15820 source { 15821 genome genomic , 15822 origin natural , 15823 org { 15824 taxname "Mus musculus" , 15825 common "house mouse" , 15826 db { 15827 { 15828 db "taxon" , 15829 tag 15830 id 10090 } } , 15831 syn { 15832 "mouse" } , 15833 orgname { 15834 name 15835 binomial { 15836 genus "Mus" , 15837 species "musculus" } , 15838 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 15839 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 15840 Sciurognathi; Muridae; Murinae; Mus" , 15841 gcode 1 , 15842 mgcode 2 , 15843 div "ROD" } } } , 15844 gene { 15845 } , 15846 gene-source { 15847 src "LocusLink" , 15848 src-int 11295 , 15849 src-str2 "11295" , 15850 gene-display FALSE , 15851 locus-display FALSE , 15852 extra-terms FALSE } , 15853 locus { 15854 { 15855 type genomic , 15856 version 0 } } , 15857 properties { 15858 { 15859 type property , 15860 label "Property" , 15861 text "phenotype only" , 15862 version 0 } } , 15863 unique-keys { 15864 { 15865 db "LocusID" , 15866 tag 15867 id 11295 } } , 15868 xtra-index-terms { 15869 "LOC109414" } , 15870 xtra-properties { 15871 { 15872 tag "PROP" , 15873 value "phenotype only" } } } 15874Entrezgene ::= { 15875 track-info { 15876 geneid 11296 , 15877 status secondary , 15878 current-id { 15879 { 15880 db "LocusID" , 15881 tag 15882 id 104236 } , 15883 { 15884 db "GeneID" , 15885 tag 15886 id 104236 } } , 15887 create-date 15888 std { 15889 year 2003 , 15890 month 8 , 15891 day 28 , 15892 hour 21 , 15893 minute 39 , 15894 second 0 } , 15895 update-date 15896 std { 15897 year 2005 , 15898 month 2 , 15899 day 17 , 15900 hour 12 , 15901 minute 54 , 15902 second 0 } } , 15903 type protein-coding , 15904 source { 15905 genome genomic , 15906 origin natural , 15907 org { 15908 taxname "Mus musculus" , 15909 common "house mouse" , 15910 db { 15911 { 15912 db "taxon" , 15913 tag 15914 id 10090 } } , 15915 syn { 15916 "mouse" } , 15917 orgname { 15918 name 15919 binomial { 15920 genus "Mus" , 15921 species "musculus" } , 15922 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 15923 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 15924 Sciurognathi; Muridae; Murinae; Mus" , 15925 gcode 1 , 15926 mgcode 2 , 15927 div "ROD" } } } , 15928 gene { 15929 } , 15930 gene-source { 15931 src "LocusLink" , 15932 src-int 11296 , 15933 src-str2 "11296" , 15934 gene-display FALSE , 15935 locus-display FALSE , 15936 extra-terms FALSE } , 15937 locus { 15938 { 15939 type genomic , 15940 version 0 } } , 15941 unique-keys { 15942 { 15943 db "LocusID" , 15944 tag 15945 id 11296 } } , 15946 xtra-index-terms { 15947 "LOC104236" } } 15948Entrezgene ::= { 15949 track-info { 15950 geneid 11297 , 15951 status secondary , 15952 current-id { 15953 { 15954 db "LocusID" , 15955 tag 15956 id 227290 } , 15957 { 15958 db "GeneID" , 15959 tag 15960 id 227290 } } , 15961 create-date 15962 std { 15963 year 2003 , 15964 month 8 , 15965 day 28 , 15966 hour 21 , 15967 minute 39 , 15968 second 0 } , 15969 update-date 15970 std { 15971 year 2005 , 15972 month 2 , 15973 day 17 , 15974 hour 12 , 15975 minute 54 , 15976 second 0 } } , 15977 type protein-coding , 15978 source { 15979 genome genomic , 15980 origin natural , 15981 org { 15982 taxname "Mus musculus" , 15983 common "house mouse" , 15984 db { 15985 { 15986 db "taxon" , 15987 tag 15988 id 10090 } } , 15989 syn { 15990 "mouse" } , 15991 orgname { 15992 name 15993 binomial { 15994 genus "Mus" , 15995 species "musculus" } , 15996 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 15997 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 15998 Sciurognathi; Muridae; Murinae; Mus" , 15999 gcode 1 , 16000 mgcode 2 , 16001 div "ROD" } } } , 16002 gene { 16003 } , 16004 gene-source { 16005 src "LocusLink" , 16006 src-int 11297 , 16007 src-str2 "11297" , 16008 gene-display FALSE , 16009 locus-display FALSE , 16010 extra-terms FALSE } , 16011 locus { 16012 { 16013 type genomic , 16014 version 0 } } , 16015 unique-keys { 16016 { 16017 db "LocusID" , 16018 tag 16019 id 11297 } } , 16020 xtra-index-terms { 16021 "LOC227290" } } 16022Entrezgene ::= { 16023 track-info { 16024 geneid 11298 , 16025 status live , 16026 create-date 16027 std { 16028 year 2003 , 16029 month 8 , 16030 day 28 , 16031 hour 21 , 16032 minute 39 , 16033 second 0 } , 16034 update-date 16035 std { 16036 year 2005 , 16037 month 3 , 16038 day 16 , 16039 hour 16 , 16040 minute 48 , 16041 second 0 } } , 16042 type protein-coding , 16043 source { 16044 genome genomic , 16045 origin natural , 16046 org { 16047 taxname "Mus musculus" , 16048 common "house mouse" , 16049 db { 16050 { 16051 db "taxon" , 16052 tag 16053 id 10090 } } , 16054 syn { 16055 "mouse" } , 16056 orgname { 16057 name 16058 binomial { 16059 genus "Mus" , 16060 species "musculus" } , 16061 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 16062 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 16063 Sciurognathi; Muridae; Murinae; Mus" , 16064 gcode 1 , 16065 mgcode 2 , 16066 div "ROD" } } , 16067 subtype { 16068 { 16069 subtype chromosome , 16070 name "11" } } } , 16071 gene { 16072 locus "Aanat" , 16073 desc "arylalkylamine N-acetyltransferase" , 16074 maploc "11 70.0 cM" , 16075 syn { 16076 "Nat4" , 16077 "SNAT" , 16078 "Nat-2" } , 16079 locus-tag "MGI:1328365" } , 16080 prot { 16081 name { 16082 "arylalkylamine N-acetyltransferase" } } , 16083 location { 16084 { 16085 display-str "11 E2" , 16086 method 16087 map-type cyto } , 16088 { 16089 display-str "11 70.0 cM" , 16090 method 16091 map-type cM } } , 16092 gene-source { 16093 src "LocusLink" , 16094 src-int 11298 , 16095 src-str2 "11298" , 16096 gene-display FALSE , 16097 locus-display FALSE , 16098 extra-terms FALSE } , 16099 locus { 16100 { 16101 type genomic , 16102 heading "Reference" , 16103 accession "NC_000077" , 16104 version 1 , 16105 seqs { 16106 int { 16107 from 116264815 , 16108 to 116268672 , 16109 strand plus , 16110 id 16111 gi 51868608 } } , 16112 products { 16113 { 16114 type mRNA , 16115 heading "Reference" , 16116 accession "NM_009591" , 16117 version 1 , 16118 genomic-coords { 16119 mix { 16120 int { 16121 from 116264815 , 16122 to 116264902 , 16123 strand plus , 16124 id 16125 gi 51868608 } , 16126 int { 16127 from 116266704 , 16128 to 116266921 , 16129 strand plus , 16130 id 16131 gi 51868608 } , 16132 int { 16133 from 116267254 , 16134 to 116267408 , 16135 strand plus , 16136 id 16137 gi 51868608 } , 16138 int { 16139 from 116267917 , 16140 to 116268672 , 16141 strand plus , 16142 id 16143 gi 51868608 } } } , 16144 seqs { 16145 whole 16146 gi 6752937 } , 16147 products { 16148 { 16149 type peptide , 16150 heading "Reference" , 16151 accession "NP_033721" , 16152 version 1 , 16153 genomic-coords { 16154 packed-int { 16155 { 16156 from 116266765 , 16157 to 116266921 , 16158 strand plus , 16159 id 16160 gi 51868608 } , 16161 { 16162 from 116267254 , 16163 to 116267408 , 16164 strand plus , 16165 id 16166 gi 51868608 } , 16167 { 16168 from 116267917 , 16169 to 116268222 , 16170 strand plus , 16171 id 16172 gi 51868608 } } } , 16173 seqs { 16174 whole 16175 gi 6752938 } } } } } } , 16176 { 16177 type genomic , 16178 heading "Reference" , 16179 accession "NT_039521" , 16180 version 3 , 16181 seqs { 16182 int { 16183 from 27994169 , 16184 to 27998026 , 16185 strand plus , 16186 id 16187 gi 51766637 } } , 16188 products { 16189 { 16190 type mRNA , 16191 heading "Reference" , 16192 accession "NM_009591" , 16193 version 1 , 16194 genomic-coords { 16195 mix { 16196 int { 16197 from 27994169 , 16198 to 27994256 , 16199 strand plus , 16200 id 16201 gi 51766637 } , 16202 int { 16203 from 27996058 , 16204 to 27996275 , 16205 strand plus , 16206 id 16207 gi 51766637 } , 16208 int { 16209 from 27996608 , 16210 to 27996762 , 16211 strand plus , 16212 id 16213 gi 51766637 } , 16214 int { 16215 from 27997271 , 16216 to 27998026 , 16217 strand plus , 16218 id 16219 gi 51766637 } } } , 16220 seqs { 16221 whole 16222 gi 6752937 } , 16223 products { 16224 { 16225 type peptide , 16226 heading "Reference" , 16227 accession "NP_033721" , 16228 version 1 , 16229 genomic-coords { 16230 packed-int { 16231 { 16232 from 27996119 , 16233 to 27996275 , 16234 strand plus , 16235 id 16236 gi 51766637 } , 16237 { 16238 from 27996608 , 16239 to 27996762 , 16240 strand plus , 16241 id 16242 gi 51766637 } , 16243 { 16244 from 27997271 , 16245 to 27997576 , 16246 strand plus , 16247 id 16248 gi 51766637 } } } , 16249 seqs { 16250 whole 16251 gi 6752938 } } } } } } } , 16252 properties { 16253 { 16254 type comment , 16255 label "Nomenclature" , 16256 version 0 , 16257 source { 16258 { 16259 anchor "Mouse Genome Informatics" } } , 16260 properties { 16261 { 16262 type property , 16263 label "Official Symbol" , 16264 text "Aanat" , 16265 version 0 } , 16266 { 16267 type property , 16268 label "Official Full Name" , 16269 text "arylalkylamine N-acetyltransferase" , 16270 version 0 } } } , 16271 { 16272 type comment , 16273 heading "GeneOntology" , 16274 version 0 , 16275 source { 16276 { 16277 pre-text "Provided by" , 16278 anchor "MGI" , 16279 url "http://www.informatics.jax.org/" } } , 16280 comment { 16281 { 16282 type comment , 16283 label "Function" , 16284 version 0 , 16285 comment { 16286 { 16287 type comment , 16288 version 0 , 16289 source { 16290 { 16291 src { 16292 db "GO" , 16293 tag 16294 id 8080 } , 16295 anchor "N-acetyltransferase activity" , 16296 post-text "evidence: IEA" } } } , 16297 { 16298 type comment , 16299 version 0 , 16300 source { 16301 { 16302 src { 16303 db "GO" , 16304 tag 16305 id 8415 } , 16306 anchor "acyltransferase activity" , 16307 post-text "evidence: IEA" } } } , 16308 { 16309 type comment , 16310 version 0 , 16311 source { 16312 { 16313 src { 16314 db "GO" , 16315 tag 16316 id 4060 } , 16317 anchor "arylamine N-acetyltransferase activity" , 16318 post-text "evidence: IEA" } } } , 16319 { 16320 type comment , 16321 version 0 , 16322 source { 16323 { 16324 src { 16325 db "GO" , 16326 tag 16327 id 16740 } , 16328 anchor "transferase activity" , 16329 post-text "evidence: IEA" } } } } } } } } , 16330 homology { 16331 { 16332 type comment , 16333 heading "Human, Rat" , 16334 version 0 , 16335 source { 16336 { 16337 src { 16338 db "HomoloGene" , 16339 tag 16340 id 31013 } , 16341 anchor "Map Viewer" , 16342 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=11 16343&MAPS=genes-r-org/human-chr/mouse%3A11,genes-r-org/rat-chr/mouse%3A11,genes-r- 16344org/mouse-chr11&query=e%3A11298[id]+AND+gene[obj_type]&QSTR=aanat&cmd=focus&fi 16345ll=10" } } } } , 16346 comments { 16347 { 16348 type comment , 16349 heading "LocusTagLink" , 16350 version 0 , 16351 source { 16352 { 16353 src { 16354 db "MGI" , 16355 tag 16356 id 1328365 } } } } , 16357 { 16358 type comment , 16359 heading "RefSeq Status" , 16360 label "PROVISIONAL" , 16361 version 0 } , 16362 { 16363 type comment , 16364 version 0 , 16365 refs { 16366 pmid 12138020 , 16367 pmid 9838107 , 16368 pmid 9708862 } } , 16369 { 16370 type comment , 16371 heading "Markers (Sequence Tagged Sites/STS)" , 16372 version 0 , 16373 comment { 16374 { 16375 type comment , 16376 version 0 , 16377 source { 16378 { 16379 src { 16380 db "UniSTS" , 16381 tag 16382 id 126289 } , 16383 anchor "D11Mit102" , 16384 post-text "(e-PCR)" } } , 16385 comment { 16386 { 16387 type other , 16388 label "Alternate name" , 16389 text "MGI:707739" , 16390 version 0 } , 16391 { 16392 type other , 16393 label "Alternate name" , 16394 text "MPC786" , 16395 version 0 } } } } } , 16396 { 16397 type comment , 16398 heading "NCBI Reference Sequences (RefSeq)" , 16399 version 0 , 16400 products { 16401 { 16402 type mRNA , 16403 heading "mRNA Sequence" , 16404 accession "NM_009591" , 16405 version 1 , 16406 source { 16407 { 16408 src { 16409 db "Nucleotide" , 16410 tag 16411 id 6752937 } , 16412 anchor "NM_009591" } } , 16413 seqs { 16414 whole 16415 gi 6752937 } , 16416 products { 16417 { 16418 type peptide , 16419 heading "Product" , 16420 accession "NP_033721" , 16421 version 1 , 16422 source { 16423 { 16424 src { 16425 db "Protein" , 16426 tag 16427 id 6752938 } , 16428 anchor "NP_033721" , 16429 post-text "arylalkylamine N-acetyltransferase" } } , 16430 seqs { 16431 whole 16432 gi 6752938 } , 16433 comment { 16434 { 16435 type other , 16436 heading "Conserved Domains" , 16437 version 0 , 16438 source { 16439 { 16440 src { 16441 db "PROT_CDD" , 16442 tag 16443 id 6752938 } , 16444 pre-text "(1)" , 16445 anchor "summary" } } , 16446 comment { 16447 { 16448 type other , 16449 version 0 , 16450 source { 16451 { 16452 src { 16453 db "CDD" , 16454 tag 16455 id 25558 } , 16456 anchor "pfam00583: Acetyltransf_1; Acetyltransferase 16457 (GNAT) family" } } , 16458 comment { 16459 { 16460 type other , 16461 text "Location: 80 - 172 Blast Score: 118" , 16462 version 0 } } } } } } } } , 16463 comment { 16464 { 16465 type other , 16466 heading "Source Sequence" , 16467 version 0 , 16468 source { 16469 { 16470 src { 16471 db "Nucleotide" , 16472 tag 16473 str "AF004108" } , 16474 anchor "AF004108" } } , 16475 comment { 16476 { 16477 type other , 16478 version 0 } } } } } } } , 16479 { 16480 type comment , 16481 heading "Related Sequences" , 16482 version 0 , 16483 products { 16484 { 16485 type genomic , 16486 heading "Genomic" , 16487 accession "U83462" , 16488 version 1 , 16489 source { 16490 { 16491 src { 16492 db "Nucleotide" , 16493 tag 16494 id 4159794 } , 16495 anchor "U83462" } } , 16496 seqs { 16497 whole 16498 gi 4159794 } , 16499 products { 16500 { 16501 type peptide , 16502 accession "AAD08637" , 16503 version 1 , 16504 source { 16505 { 16506 src { 16507 db "Protein" , 16508 tag 16509 id 4099097 } , 16510 anchor "AAD08637" } } , 16511 seqs { 16512 whole 16513 gi 4099097 } } } , 16514 comment { 16515 { 16516 type other , 16517 label "Strain" , 16518 text "129/Sv" , 16519 version 0 } } } , 16520 { 16521 type mRNA , 16522 heading "mRNA" , 16523 accession "AB013358" , 16524 version 1 , 16525 source { 16526 { 16527 src { 16528 db "Nucleotide" , 16529 tag 16530 id 3298499 } , 16531 anchor "AB013358" } } , 16532 seqs { 16533 whole 16534 gi 3298499 } , 16535 products { 16536 { 16537 type peptide , 16538 accession "BAA31526" , 16539 version 1 , 16540 source { 16541 { 16542 src { 16543 db "Protein" , 16544 tag 16545 id 3298500 } , 16546 anchor "BAA31526" } } , 16547 seqs { 16548 whole 16549 gi 3298500 } } } , 16550 comment { 16551 { 16552 type other , 16553 label "Strain" , 16554 text "BALB/c" , 16555 version 0 } } } , 16556 { 16557 type mRNA , 16558 heading "mRNA" , 16559 accession "AF004108" , 16560 version 1 , 16561 source { 16562 { 16563 src { 16564 db "Nucleotide" , 16565 tag 16566 id 4159890 } , 16567 anchor "AF004108" } } , 16568 seqs { 16569 whole 16570 gi 4159890 } , 16571 products { 16572 { 16573 type peptide , 16574 accession "AAD09408" , 16575 version 1 , 16576 source { 16577 { 16578 src { 16579 db "Protein" , 16580 tag 16581 id 4159891 } , 16582 anchor "AAD09408" } } , 16583 seqs { 16584 whole 16585 gi 4159891 } } } , 16586 comment { 16587 { 16588 type other , 16589 label "Strain" , 16590 text "C3H/He" , 16591 version 0 } } } , 16592 { 16593 type mRNA , 16594 heading "mRNA" , 16595 accession "AF004109" , 16596 version 1 , 16597 source { 16598 { 16599 src { 16600 db "Nucleotide" , 16601 tag 16602 id 4159892 } , 16603 anchor "AF004109" } } , 16604 seqs { 16605 whole 16606 gi 4159892 } , 16607 products { 16608 { 16609 type peptide , 16610 accession "AAD09409" , 16611 version 1 , 16612 source { 16613 { 16614 src { 16615 db "Protein" , 16616 tag 16617 id 4159893 } , 16618 anchor "AAD09409" } } , 16619 seqs { 16620 whole 16621 gi 4159893 } } } , 16622 comment { 16623 { 16624 type other , 16625 label "Strain" , 16626 text "C3H/He" , 16627 version 0 } } } , 16628 { 16629 type mRNA , 16630 heading "mRNA" , 16631 accession "AF004110" , 16632 version 1 , 16633 source { 16634 { 16635 src { 16636 db "Nucleotide" , 16637 tag 16638 id 4159894 } , 16639 anchor "AF004110" } } , 16640 seqs { 16641 whole 16642 gi 4159894 } , 16643 products { 16644 { 16645 type peptide , 16646 accession "AAD09410" , 16647 version 1 , 16648 source { 16649 { 16650 src { 16651 db "Protein" , 16652 tag 16653 id 4159895 } , 16654 anchor "AAD09410" } } , 16655 seqs { 16656 whole 16657 gi 4159895 } } } , 16658 comment { 16659 { 16660 type other , 16661 label "Strain" , 16662 text "C57BL/6" , 16663 version 0 } } } , 16664 { 16665 type mRNA , 16666 heading "mRNA" , 16667 accession "AF004111" , 16668 version 1 , 16669 source { 16670 { 16671 src { 16672 db "Nucleotide" , 16673 tag 16674 id 4159896 } , 16675 anchor "AF004111" } } , 16676 seqs { 16677 whole 16678 gi 4159896 } , 16679 products { 16680 { 16681 type peptide , 16682 accession "AAD09411" , 16683 version 1 , 16684 source { 16685 { 16686 src { 16687 db "Protein" , 16688 tag 16689 id 4159897 } , 16690 anchor "AAD09411" } } , 16691 seqs { 16692 whole 16693 gi 4159897 } } } , 16694 comment { 16695 { 16696 type other , 16697 label "Strain" , 16698 text "C57BL/6" , 16699 version 0 } } } , 16700 { 16701 type other , 16702 text "None" , 16703 version 0 , 16704 products { 16705 { 16706 type peptide , 16707 accession "O88816" , 16708 version 0 , 16709 source { 16710 { 16711 src { 16712 db "Protein" , 16713 tag 16714 id 11387071 } , 16715 anchor "O88816" } } , 16716 seqs { 16717 whole 16718 gi 11387071 } } } } } } , 16719 { 16720 type comment , 16721 heading "Additional Links" , 16722 version 0 , 16723 comment { 16724 { 16725 type comment , 16726 version 0 , 16727 source { 16728 { 16729 src { 16730 db "Evidence Viewer" , 16731 tag 16732 str "11298" } , 16733 anchor "Evidence Viewer" , 16734 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont 16735ig=NT_039521.3&gene=Aanat&lid=11298&from=27994170&to=27998027" } } } , 16736 { 16737 type comment , 16738 version 0 , 16739 source { 16740 { 16741 src { 16742 db "ModelMaker" , 16743 tag 16744 str "11298" } , 16745 anchor "ModelMaker" , 16746 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10 16747090&contig=NT_039521.3&gene=Aanat&lid=11298" } } } , 16748 { 16749 type comment , 16750 text "UniGene" , 16751 version 0 , 16752 xtra-properties { 16753 { 16754 tag "UNIGENE" , 16755 value "Mm.42233" } } , 16756 source { 16757 { 16758 src { 16759 db "UniGene" , 16760 tag 16761 str "Mm.42233" } , 16762 anchor "Mm.42233" , 16763 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=42 16764233" } } } , 16765 { 16766 type comment , 16767 version 0 , 16768 source { 16769 { 16770 src { 16771 db "HomoloGene" , 16772 tag 16773 str "11298" } , 16774 anchor "HomoloGene" , 16775 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 1677611298[loc]&TAXID=10090" } } } , 16777 { 16778 type comment , 16779 version 0 , 16780 source { 16781 { 16782 src { 16783 db "MGI" , 16784 tag 16785 id 1328365 } , 16786 anchor "MGI" , 16787 url "http://www.informatics.jax.org/searches/accession_report.cg 16788i?id=MGI:1328365" } } } , 16789 { 16790 type comment , 16791 version 0 , 16792 source { 16793 { 16794 src { 16795 db "Ensembl" , 16796 tag 16797 str "" } , 16798 url "http://www.ensembl.org/Mus_musculus/contigview?geneid=AF004 16799110" } } } , 16800 { 16801 type comment , 16802 version 0 , 16803 source { 16804 { 16805 src { 16806 db "UCSC" , 16807 tag 16808 str "" } , 16809 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position= 16810AF004110" } } } } } , 16811 { 16812 type generif , 16813 text "AANAT expression and synthesis of N-acetylserotonin/melatonin 16814 could play a role in addictive properties of cocaine" , 16815 version 0 , 16816 refs { 16817 pmid 12138020 } , 16818 create-date 16819 str "Aug 19 2002 12:00AM" , 16820 update-date 16821 str "Aug 28 2002 6:19PM" } } , 16822 unique-keys { 16823 { 16824 db "LocusID" , 16825 tag 16826 id 11298 } , 16827 { 16828 db "MGI" , 16829 tag 16830 id 1328365 } } , 16831 xtra-index-terms { 16832 "LOC11298" } } 16833Entrezgene ::= { 16834 track-info { 16835 geneid 11299 , 16836 status secondary , 16837 current-id { 16838 { 16839 db "LocusID" , 16840 tag 16841 id 20249 } , 16842 { 16843 db "GeneID" , 16844 tag 16845 id 20249 } } , 16846 create-date 16847 std { 16848 year 2003 , 16849 month 8 , 16850 day 28 , 16851 hour 21 , 16852 minute 39 , 16853 second 0 } , 16854 update-date 16855 std { 16856 year 2005 , 16857 month 2 , 16858 day 17 , 16859 hour 12 , 16860 minute 54 , 16861 second 0 } } , 16862 type unknown , 16863 source { 16864 genome genomic , 16865 origin natural , 16866 org { 16867 taxname "Mus musculus" , 16868 common "house mouse" , 16869 db { 16870 { 16871 db "taxon" , 16872 tag 16873 id 10090 } } , 16874 syn { 16875 "mouse" } , 16876 orgname { 16877 name 16878 binomial { 16879 genus "Mus" , 16880 species "musculus" } , 16881 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 16882 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 16883 Sciurognathi; Muridae; Murinae; Mus" , 16884 gcode 1 , 16885 mgcode 2 , 16886 div "ROD" } } } , 16887 gene { 16888 } , 16889 gene-source { 16890 src "LocusLink" , 16891 src-int 11299 , 16892 src-str2 "11299" , 16893 gene-display FALSE , 16894 locus-display FALSE , 16895 extra-terms FALSE } , 16896 locus { 16897 { 16898 type genomic , 16899 version 0 } } , 16900 properties { 16901 { 16902 type property , 16903 label "Property" , 16904 text "phenotype only" , 16905 version 0 } } , 16906 unique-keys { 16907 { 16908 db "LocusID" , 16909 tag 16910 id 11299 } } , 16911 xtra-index-terms { 16912 "LOC20249" } , 16913 xtra-properties { 16914 { 16915 tag "PROP" , 16916 value "phenotype only" } } } 16917Entrezgene ::= { 16918 track-info { 16919 geneid 11300 , 16920 status secondary , 16921 current-id { 16922 { 16923 db "LocusID" , 16924 tag 16925 id 112133 } , 16926 { 16927 db "GeneID" , 16928 tag 16929 id 112133 } } , 16930 create-date 16931 std { 16932 year 2003 , 16933 month 8 , 16934 day 28 , 16935 hour 21 , 16936 minute 39 , 16937 second 0 } , 16938 update-date 16939 std { 16940 year 2005 , 16941 month 2 , 16942 day 17 , 16943 hour 12 , 16944 minute 54 , 16945 second 0 } } , 16946 type unknown , 16947 source { 16948 genome genomic , 16949 origin natural , 16950 org { 16951 taxname "Mus musculus" , 16952 common "house mouse" , 16953 db { 16954 { 16955 db "taxon" , 16956 tag 16957 id 10090 } } , 16958 syn { 16959 "mouse" } , 16960 orgname { 16961 name 16962 binomial { 16963 genus "Mus" , 16964 species "musculus" } , 16965 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 16966 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 16967 Sciurognathi; Muridae; Murinae; Mus" , 16968 gcode 1 , 16969 mgcode 2 , 16970 div "ROD" } } } , 16971 gene { 16972 } , 16973 gene-source { 16974 src "LocusLink" , 16975 src-int 11300 , 16976 src-str2 "11300" , 16977 gene-display FALSE , 16978 locus-display FALSE , 16979 extra-terms FALSE } , 16980 locus { 16981 { 16982 type genomic , 16983 version 0 } } , 16984 properties { 16985 { 16986 type property , 16987 label "Property" , 16988 text "phenotype only" , 16989 version 0 } } , 16990 unique-keys { 16991 { 16992 db "LocusID" , 16993 tag 16994 id 11300 } } , 16995 xtra-index-terms { 16996 "LOC112133" } , 16997 xtra-properties { 16998 { 16999 tag "PROP" , 17000 value "phenotype only" } } } 17001Entrezgene ::= { 17002 track-info { 17003 geneid 11301 , 17004 status secondary , 17005 current-id { 17006 { 17007 db "LocusID" , 17008 tag 17009 id 20700 } , 17010 { 17011 db "GeneID" , 17012 tag 17013 id 20700 } } , 17014 create-date 17015 std { 17016 year 2003 , 17017 month 8 , 17018 day 28 , 17019 hour 21 , 17020 minute 39 , 17021 second 0 } , 17022 update-date 17023 std { 17024 year 2005 , 17025 month 3 , 17026 day 9 , 17027 hour 17 , 17028 minute 35 , 17029 second 0 } } , 17030 type protein-coding , 17031 source { 17032 genome genomic , 17033 origin natural , 17034 org { 17035 taxname "Mus musculus" , 17036 common "house mouse" , 17037 db { 17038 { 17039 db "taxon" , 17040 tag 17041 id 10090 } } , 17042 syn { 17043 "mouse" } , 17044 orgname { 17045 name 17046 binomial { 17047 genus "Mus" , 17048 species "musculus" } , 17049 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 17050 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 17051 Sciurognathi; Muridae; Murinae; Mus" , 17052 gcode 1 , 17053 mgcode 2 , 17054 div "ROD" } } } , 17055 gene { 17056 } , 17057 gene-source { 17058 src "LocusLink" , 17059 src-int 11301 , 17060 src-str2 "11301" , 17061 gene-display FALSE , 17062 locus-display FALSE , 17063 extra-terms FALSE } , 17064 locus { 17065 { 17066 type genomic , 17067 version 0 } } , 17068 unique-keys { 17069 { 17070 db "LocusID" , 17071 tag 17072 id 11301 } } , 17073 xtra-index-terms { 17074 "LOC20700" } } 17075Entrezgene ::= { 17076 track-info { 17077 geneid 11302 , 17078 status live , 17079 create-date 17080 std { 17081 year 2003 , 17082 month 8 , 17083 day 28 , 17084 hour 21 , 17085 minute 39 , 17086 second 0 } , 17087 update-date 17088 std { 17089 year 2005 , 17090 month 3 , 17091 day 26 , 17092 hour 10 , 17093 minute 32 , 17094 second 0 } } , 17095 type protein-coding , 17096 source { 17097 genome genomic , 17098 origin natural , 17099 org { 17100 taxname "Mus musculus" , 17101 common "house mouse" , 17102 db { 17103 { 17104 db "taxon" , 17105 tag 17106 id 10090 } } , 17107 syn { 17108 "mouse" } , 17109 orgname { 17110 name 17111 binomial { 17112 genus "Mus" , 17113 species "musculus" } , 17114 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 17115 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 17116 Sciurognathi; Muridae; Murinae; Mus" , 17117 gcode 1 , 17118 mgcode 2 , 17119 div "ROD" } } , 17120 subtype { 17121 { 17122 subtype chromosome , 17123 name "11" } } } , 17124 gene { 17125 locus "Aatk" , 17126 desc "apoptosis-associated tyrosine kinase" , 17127 maploc "11 E2" , 17128 syn { 17129 "AATYK" , 17130 "mKIAA0641" } , 17131 locus-tag "MGI:1197518" } , 17132 prot { 17133 name { 17134 "apoptosis-associated tyrosine kinase" } } , 17135 location { 17136 { 17137 display-str "11 E2" , 17138 method 17139 map-type cyto } } , 17140 gene-source { 17141 src "LocusLink" , 17142 src-int 11302 , 17143 src-str2 "11302" , 17144 gene-display FALSE , 17145 locus-display FALSE , 17146 extra-terms FALSE } , 17147 locus { 17148 { 17149 type genomic , 17150 heading "Reference" , 17151 accession "NC_000077" , 17152 version 1 , 17153 seqs { 17154 int { 17155 from 119678449 , 17156 to 119692677 , 17157 strand minus , 17158 id 17159 gi 51868608 } } , 17160 products { 17161 { 17162 type mRNA , 17163 heading "Reference" , 17164 accession "NM_007377" , 17165 version 1 , 17166 genomic-coords { 17167 mix { 17168 int { 17169 from 119678449 , 17170 to 119679572 , 17171 strand minus , 17172 id 17173 gi 51868608 } , 17174 int { 17175 from 119680403 , 17176 to 119680603 , 17177 strand minus , 17178 id 17179 gi 51868608 } , 17180 int { 17181 from 119680735 , 17182 to 119680882 , 17183 strand minus , 17184 id 17185 gi 51868608 } , 17186 int { 17187 from 119680962 , 17188 to 119683554 , 17189 strand minus , 17190 id 17191 gi 51868608 } , 17192 int { 17193 from 119683851 , 17194 to 119684000 , 17195 strand minus , 17196 id 17197 gi 51868608 } , 17198 int { 17199 from 119684576 , 17200 to 119684697 , 17201 strand minus , 17202 id 17203 gi 51868608 } , 17204 int { 17205 from 119684778 , 17206 to 119684862 , 17207 strand minus , 17208 id 17209 gi 51868608 } , 17210 int { 17211 from 119686587 , 17212 to 119686720 , 17213 strand minus , 17214 id 17215 gi 51868608 } , 17216 int { 17217 from 119687234 , 17218 to 119687321 , 17219 strand minus , 17220 id 17221 gi 51868608 } , 17222 int { 17223 from 119687441 , 17224 to 119687559 , 17225 strand minus , 17226 id 17227 gi 51868608 } , 17228 int { 17229 from 119687856 , 17230 to 119687935 , 17231 strand minus , 17232 id 17233 gi 51868608 } , 17234 int { 17235 from 119689873 , 17236 to 119690020 , 17237 strand minus , 17238 id 17239 gi 51868608 } , 17240 int { 17241 from 119692530 , 17242 to 119692677 , 17243 strand minus , 17244 id 17245 gi 51868608 } } } , 17246 seqs { 17247 whole 17248 gi 6680609 } , 17249 products { 17250 { 17251 type peptide , 17252 heading "Reference" , 17253 accession "NP_031403" , 17254 version 1 , 17255 genomic-coords { 17256 packed-int { 17257 { 17258 from 119679532 , 17259 to 119679572 , 17260 strand minus , 17261 id 17262 gi 51868608 } , 17263 { 17264 from 119680403 , 17265 to 119680603 , 17266 strand minus , 17267 id 17268 gi 51868608 } , 17269 { 17270 from 119680735 , 17271 to 119680882 , 17272 strand minus , 17273 id 17274 gi 51868608 } , 17275 { 17276 from 119680962 , 17277 to 119683554 , 17278 strand minus , 17279 id 17280 gi 51868608 } , 17281 { 17282 from 119683851 , 17283 to 119684000 , 17284 strand minus , 17285 id 17286 gi 51868608 } , 17287 { 17288 from 119684576 , 17289 to 119684697 , 17290 strand minus , 17291 id 17292 gi 51868608 } , 17293 { 17294 from 119684778 , 17295 to 119684862 , 17296 strand minus , 17297 id 17298 gi 51868608 } , 17299 { 17300 from 119686587 , 17301 to 119686720 , 17302 strand minus , 17303 id 17304 gi 51868608 } , 17305 { 17306 from 119687234 , 17307 to 119687321 , 17308 strand minus , 17309 id 17310 gi 51868608 } , 17311 { 17312 from 119687441 , 17313 to 119687559 , 17314 strand minus , 17315 id 17316 gi 51868608 } , 17317 { 17318 from 119687856 , 17319 to 119687935 , 17320 strand minus , 17321 id 17322 gi 51868608 } , 17323 { 17324 from 119689873 , 17325 to 119690020 , 17326 strand minus , 17327 id 17328 gi 51868608 } , 17329 { 17330 from 119692530 , 17331 to 119692574 , 17332 strand minus , 17333 id 17334 gi 51868608 } } } , 17335 seqs { 17336 whole 17337 gi 6680610 } } } } } } , 17338 { 17339 type genomic , 17340 heading "Reference" , 17341 accession "NT_039521" , 17342 version 3 , 17343 seqs { 17344 int { 17345 from 31407803 , 17346 to 31422031 , 17347 strand minus , 17348 id 17349 gi 51766637 } } , 17350 products { 17351 { 17352 type mRNA , 17353 heading "Reference" , 17354 accession "NM_007377" , 17355 version 1 , 17356 genomic-coords { 17357 mix { 17358 int { 17359 from 31407803 , 17360 to 31408926 , 17361 strand minus , 17362 id 17363 gi 51766637 } , 17364 int { 17365 from 31409757 , 17366 to 31409957 , 17367 strand minus , 17368 id 17369 gi 51766637 } , 17370 int { 17371 from 31410089 , 17372 to 31410236 , 17373 strand minus , 17374 id 17375 gi 51766637 } , 17376 int { 17377 from 31410316 , 17378 to 31412908 , 17379 strand minus , 17380 id 17381 gi 51766637 } , 17382 int { 17383 from 31413205 , 17384 to 31413354 , 17385 strand minus , 17386 id 17387 gi 51766637 } , 17388 int { 17389 from 31413930 , 17390 to 31414051 , 17391 strand minus , 17392 id 17393 gi 51766637 } , 17394 int { 17395 from 31414132 , 17396 to 31414216 , 17397 strand minus , 17398 id 17399 gi 51766637 } , 17400 int { 17401 from 31415941 , 17402 to 31416074 , 17403 strand minus , 17404 id 17405 gi 51766637 } , 17406 int { 17407 from 31416588 , 17408 to 31416675 , 17409 strand minus , 17410 id 17411 gi 51766637 } , 17412 int { 17413 from 31416795 , 17414 to 31416913 , 17415 strand minus , 17416 id 17417 gi 51766637 } , 17418 int { 17419 from 31417210 , 17420 to 31417289 , 17421 strand minus , 17422 id 17423 gi 51766637 } , 17424 int { 17425 from 31419227 , 17426 to 31419374 , 17427 strand minus , 17428 id 17429 gi 51766637 } , 17430 int { 17431 from 31421884 , 17432 to 31422031 , 17433 strand minus , 17434 id 17435 gi 51766637 } } } , 17436 seqs { 17437 whole 17438 gi 6680609 } , 17439 products { 17440 { 17441 type peptide , 17442 heading "Reference" , 17443 accession "NP_031403" , 17444 version 1 , 17445 genomic-coords { 17446 packed-int { 17447 { 17448 from 31408886 , 17449 to 31408926 , 17450 strand minus , 17451 id 17452 gi 51766637 } , 17453 { 17454 from 31409757 , 17455 to 31409957 , 17456 strand minus , 17457 id 17458 gi 51766637 } , 17459 { 17460 from 31410089 , 17461 to 31410236 , 17462 strand minus , 17463 id 17464 gi 51766637 } , 17465 { 17466 from 31410316 , 17467 to 31412908 , 17468 strand minus , 17469 id 17470 gi 51766637 } , 17471 { 17472 from 31413205 , 17473 to 31413354 , 17474 strand minus , 17475 id 17476 gi 51766637 } , 17477 { 17478 from 31413930 , 17479 to 31414051 , 17480 strand minus , 17481 id 17482 gi 51766637 } , 17483 { 17484 from 31414132 , 17485 to 31414216 , 17486 strand minus , 17487 id 17488 gi 51766637 } , 17489 { 17490 from 31415941 , 17491 to 31416074 , 17492 strand minus , 17493 id 17494 gi 51766637 } , 17495 { 17496 from 31416588 , 17497 to 31416675 , 17498 strand minus , 17499 id 17500 gi 51766637 } , 17501 { 17502 from 31416795 , 17503 to 31416913 , 17504 strand minus , 17505 id 17506 gi 51766637 } , 17507 { 17508 from 31417210 , 17509 to 31417289 , 17510 strand minus , 17511 id 17512 gi 51766637 } , 17513 { 17514 from 31419227 , 17515 to 31419374 , 17516 strand minus , 17517 id 17518 gi 51766637 } , 17519 { 17520 from 31421884 , 17521 to 31421928 , 17522 strand minus , 17523 id 17524 gi 51766637 } } } , 17525 seqs { 17526 whole 17527 gi 6680610 } } } } } } } , 17528 properties { 17529 { 17530 type comment , 17531 label "Nomenclature" , 17532 version 0 , 17533 source { 17534 { 17535 anchor "Mouse Genome Informatics" } } , 17536 properties { 17537 { 17538 type property , 17539 label "Official Symbol" , 17540 text "Aatk" , 17541 version 0 } , 17542 { 17543 type property , 17544 label "Official Full Name" , 17545 text "apoptosis-associated tyrosine kinase" , 17546 version 0 } } } , 17547 { 17548 type comment , 17549 heading "GeneOntology" , 17550 version 0 , 17551 source { 17552 { 17553 pre-text "Provided by" , 17554 anchor "MGI" , 17555 url "http://www.informatics.jax.org/" } } , 17556 comment { 17557 { 17558 type comment , 17559 label "Function" , 17560 version 0 , 17561 comment { 17562 { 17563 type comment , 17564 version 0 , 17565 source { 17566 { 17567 src { 17568 db "GO" , 17569 tag 17570 id 5524 } , 17571 anchor "ATP binding" , 17572 post-text "evidence: IEA" } } } , 17573 { 17574 type comment , 17575 version 0 , 17576 source { 17577 { 17578 src { 17579 db "GO" , 17580 tag 17581 id 16301 } , 17582 anchor "kinase activity" , 17583 post-text "evidence: IEA" } } } , 17584 { 17585 type comment , 17586 version 0 , 17587 refs { 17588 pmid 12466851 } , 17589 source { 17590 { 17591 src { 17592 db "GO" , 17593 tag 17594 id 4672 } , 17595 anchor "protein kinase activity" , 17596 post-text "evidence: ISS" } } } , 17597 { 17598 type comment , 17599 version 0 , 17600 refs { 17601 pmid 12466851 } , 17602 source { 17603 { 17604 src { 17605 db "GO" , 17606 tag 17607 id 4674 } , 17608 anchor "protein serine/threonine kinase activity" , 17609 post-text "evidence: ISS" } } } , 17610 { 17611 type comment , 17612 version 0 , 17613 refs { 17614 pmid 9444961 } , 17615 source { 17616 { 17617 src { 17618 db "GO" , 17619 tag 17620 id 4713 } , 17621 anchor "protein-tyrosine kinase activity" , 17622 post-text "evidence: ISS" } } } , 17623 { 17624 type comment , 17625 version 0 , 17626 source { 17627 { 17628 src { 17629 db "GO" , 17630 tag 17631 id 16740 } , 17632 anchor "transferase activity" , 17633 post-text "evidence: IEA" } } } } } , 17634 { 17635 type comment , 17636 label "Process" , 17637 version 0 , 17638 comment { 17639 { 17640 type comment , 17641 version 0 , 17642 refs { 17643 pmid 9444961 } , 17644 source { 17645 { 17646 src { 17647 db "GO" , 17648 tag 17649 id 6915 } , 17650 anchor "apoptosis" , 17651 post-text "evidence: IDA" } } } , 17652 { 17653 type comment , 17654 version 0 , 17655 refs { 17656 pmid 12466851 } , 17657 source { 17658 { 17659 src { 17660 db "GO" , 17661 tag 17662 id 6468 } , 17663 anchor "protein amino acid phosphorylation" , 17664 post-text "evidence: ISS" } } } } } } } } , 17665 homology { 17666 { 17667 type comment , 17668 heading "Rat" , 17669 version 0 , 17670 source { 17671 { 17672 src { 17673 db "HomoloGene" , 17674 tag 17675 id 7223 } , 17676 anchor "Map Viewer" , 17677 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=11 17678&MAPS=genes-r-org/rat-chr/mouse%3A11,genes-r-org/mouse-chr11&query=e%3A11302[i 17679d]+AND+gene[obj_type]&QSTR=aatk&cmd=focus&fill=10" } } } } , 17680 comments { 17681 { 17682 type comment , 17683 heading "LocusTagLink" , 17684 version 0 , 17685 source { 17686 { 17687 src { 17688 db "MGI" , 17689 tag 17690 id 1197518 } } } } , 17691 { 17692 type comment , 17693 heading "RefSeq Status" , 17694 label "PROVISIONAL" , 17695 version 0 } , 17696 { 17697 type comment , 17698 version 0 , 17699 refs { 17700 pmid 12670708 , 17701 pmid 12477932 , 17702 pmid 12466851 , 17703 pmid 11314039 , 17704 pmid 11217851 , 17705 pmid 11076861 , 17706 pmid 11042159 , 17707 pmid 10349636 , 17708 pmid 9444961 } } , 17709 { 17710 type comment , 17711 heading "NCBI Reference Sequences (RefSeq)" , 17712 version 0 , 17713 products { 17714 { 17715 type mRNA , 17716 heading "mRNA Sequence" , 17717 accession "NM_007377" , 17718 version 2 , 17719 source { 17720 { 17721 src { 17722 db "Nucleotide" , 17723 tag 17724 id 52345410 } , 17725 anchor "NM_007377" } } , 17726 seqs { 17727 whole 17728 gi 52345410 } , 17729 products { 17730 { 17731 type peptide , 17732 heading "Product" , 17733 accession "NP_031403" , 17734 version 2 , 17735 source { 17736 { 17737 src { 17738 db "Protein" , 17739 tag 17740 id 52345411 } , 17741 anchor "NP_031403" , 17742 post-text "apoptosis-associated tyrosine kinase" } } , 17743 seqs { 17744 whole 17745 gi 52345411 } , 17746 comment { 17747 { 17748 type other , 17749 heading "Conserved Domains" , 17750 version 0 , 17751 source { 17752 { 17753 src { 17754 db "PROT_CDD" , 17755 tag 17756 id 52345411 } , 17757 pre-text "(1)" , 17758 anchor "summary" } } , 17759 comment { 17760 { 17761 type other , 17762 version 0 , 17763 source { 17764 { 17765 src { 17766 db "CDD" , 17767 tag 17768 id 5392 } , 17769 anchor "cd00192: TyrKc; Tyrosine kinase, catalytic 17770 domain" } } , 17771 comment { 17772 { 17773 type other , 17774 text "Location: 75 - 348 Blast Score: 588" , 17775 version 0 } } } } } } } } , 17776 comment { 17777 { 17778 type other , 17779 heading "Source Sequence" , 17780 version 0 , 17781 source { 17782 { 17783 src { 17784 db "Nucleotide" , 17785 tag 17786 str "BC080846" } , 17787 anchor "BC080846" } } , 17788 comment { 17789 { 17790 type other , 17791 version 0 } } } } } } } , 17792 { 17793 type comment , 17794 heading "Related Sequences" , 17795 version 0 , 17796 products { 17797 { 17798 type mRNA , 17799 heading "mRNA" , 17800 accession "AB093253" , 17801 version 2 , 17802 source { 17803 { 17804 src { 17805 db "Nucleotide" , 17806 tag 17807 id 39104554 } , 17808 anchor "AB093253" } } , 17809 seqs { 17810 whole 17811 gi 39104554 } , 17812 products { 17813 { 17814 type peptide , 17815 accession "BAC41437" , 17816 version 2 , 17817 source { 17818 { 17819 src { 17820 db "Protein" , 17821 tag 17822 id 39104555 } , 17823 anchor "BAC41437" } } , 17824 seqs { 17825 whole 17826 gi 39104555 } } } } , 17827 { 17828 type mRNA , 17829 heading "mRNA" , 17830 accession "AF011908" , 17831 version 1 , 17832 source { 17833 { 17834 src { 17835 db "Nucleotide" , 17836 tag 17837 id 2459992 } , 17838 anchor "AF011908" } } , 17839 seqs { 17840 whole 17841 gi 2459992 } , 17842 products { 17843 { 17844 type peptide , 17845 accession "AAB71837" , 17846 version 1 , 17847 source { 17848 { 17849 src { 17850 db "Protein" , 17851 tag 17852 id 2459993 } , 17853 anchor "AAB71837" } } , 17854 seqs { 17855 whole 17856 gi 2459993 } } } } , 17857 { 17858 type mRNA , 17859 heading "mRNA" , 17860 accession "AK036705" , 17861 version 1 , 17862 source { 17863 { 17864 src { 17865 db "Nucleotide" , 17866 tag 17867 id 26331621 } , 17868 anchor "AK036705" } } , 17869 seqs { 17870 whole 17871 gi 26331621 } , 17872 products { 17873 { 17874 type peptide , 17875 accession "BAC29541" , 17876 version 1 , 17877 source { 17878 { 17879 src { 17880 db "Protein" , 17881 tag 17882 id 26331622 } , 17883 anchor "BAC29541" } } , 17884 seqs { 17885 whole 17886 gi 26331622 } } } , 17887 comment { 17888 { 17889 type other , 17890 label "Strain" , 17891 text "C57BL/6J" , 17892 version 0 } } } , 17893 { 17894 type mRNA , 17895 heading "mRNA" , 17896 accession "AK076214" , 17897 version 1 , 17898 source { 17899 { 17900 src { 17901 db "Nucleotide" , 17902 tag 17903 id 26096668 } , 17904 anchor "AK076214" } } , 17905 seqs { 17906 whole 17907 gi 26096668 } , 17908 products { 17909 { 17910 type peptide , 17911 text "None" , 17912 version 0 } } , 17913 comment { 17914 { 17915 type other , 17916 label "Strain" , 17917 text "C57BL/6J" , 17918 version 0 } } } , 17919 { 17920 type mRNA , 17921 heading "mRNA" , 17922 accession "AY236858" , 17923 version 1 , 17924 source { 17925 { 17926 src { 17927 db "Nucleotide" , 17928 tag 17929 id 29824955 } , 17930 anchor "AY236858" } } , 17931 seqs { 17932 whole 17933 gi 29824955 } , 17934 products { 17935 { 17936 type peptide , 17937 accession "AAO92350" , 17938 version 1 , 17939 source { 17940 { 17941 src { 17942 db "Protein" , 17943 tag 17944 id 29824956 } , 17945 anchor "AAO92350" } } , 17946 seqs { 17947 whole 17948 gi 29824956 } } } } , 17949 { 17950 type mRNA , 17951 heading "mRNA" , 17952 accession "AY236859" , 17953 version 1 , 17954 source { 17955 { 17956 src { 17957 db "Nucleotide" , 17958 tag 17959 id 29824957 } , 17960 anchor "AY236859" } } , 17961 seqs { 17962 whole 17963 gi 29824957 } , 17964 products { 17965 { 17966 type peptide , 17967 accession "AAO92351" , 17968 version 1 , 17969 source { 17970 { 17971 src { 17972 db "Protein" , 17973 tag 17974 id 29824958 } , 17975 anchor "AAO92351" } } , 17976 seqs { 17977 whole 17978 gi 29824958 } } } , 17979 comment { 17980 { 17981 type other , 17982 label "Strain" , 17983 text "129/SvJ" , 17984 version 0 } } } , 17985 { 17986 type mRNA , 17987 heading "mRNA" , 17988 accession "BC042837" , 17989 version 1 , 17990 source { 17991 { 17992 src { 17993 db "Nucleotide" , 17994 tag 17995 id 27769340 } , 17996 anchor "BC042837" } } , 17997 seqs { 17998 whole 17999 gi 27769340 } , 18000 products { 18001 { 18002 type peptide , 18003 text "None" , 18004 version 0 } } } , 18005 { 18006 type mRNA , 18007 heading "mRNA" , 18008 accession "BC052323" , 18009 version 1 , 18010 source { 18011 { 18012 src { 18013 db "Nucleotide" , 18014 tag 18015 id 30410866 } , 18016 anchor "BC052323" } } , 18017 seqs { 18018 whole 18019 gi 30410866 } , 18020 products { 18021 { 18022 type peptide , 18023 text "None" , 18024 version 0 } } } , 18025 { 18026 type mRNA , 18027 heading "mRNA" , 18028 accession "BC080846" , 18029 version 1 , 18030 source { 18031 { 18032 src { 18033 db "Nucleotide" , 18034 tag 18035 id 51593713 } , 18036 anchor "BC080846" } } , 18037 seqs { 18038 whole 18039 gi 51593713 } , 18040 products { 18041 { 18042 type peptide , 18043 accession "AAH80846" , 18044 version 1 , 18045 source { 18046 { 18047 src { 18048 db "Protein" , 18049 tag 18050 id 51593714 } , 18051 anchor "AAH80846" } } , 18052 seqs { 18053 whole 18054 gi 51593714 } } } , 18055 comment { 18056 { 18057 type other , 18058 label "Strain" , 18059 text "C57BL/6" , 18060 version 0 } } } } } , 18061 { 18062 type comment , 18063 heading "Additional Links" , 18064 version 0 , 18065 comment { 18066 { 18067 type comment , 18068 version 0 , 18069 source { 18070 { 18071 src { 18072 db "Evidence Viewer" , 18073 tag 18074 str "11302" } , 18075 anchor "Evidence Viewer" , 18076 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont 18077ig=NT_039521.3&gene=Aatk&lid=11302&from=31407804&to=31422032" } } } , 18078 { 18079 type comment , 18080 version 0 , 18081 source { 18082 { 18083 src { 18084 db "ModelMaker" , 18085 tag 18086 str "11302" } , 18087 anchor "ModelMaker" , 18088 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10 18089090&contig=NT_039521.3&gene=Aatk&lid=11302" } } } , 18090 { 18091 type comment , 18092 text "UniGene" , 18093 version 0 , 18094 xtra-properties { 18095 { 18096 tag "UNIGENE" , 18097 value "Mm.6826" } } , 18098 source { 18099 { 18100 src { 18101 db "UniGene" , 18102 tag 18103 str "Mm.6826" } , 18104 anchor "Mm.6826" , 18105 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=68 1810626" } } } , 18107 { 18108 type comment , 18109 version 0 , 18110 source { 18111 { 18112 src { 18113 db "HomoloGene" , 18114 tag 18115 str "11302" } , 18116 anchor "HomoloGene" , 18117 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 1811811302[loc]&TAXID=10090" } } } , 18119 { 18120 type comment , 18121 version 0 , 18122 source { 18123 { 18124 src { 18125 db "MGI" , 18126 tag 18127 id 1197518 } , 18128 anchor "MGI" , 18129 url "http://www.informatics.jax.org/searches/accession_report.cg 18130i?id=MGI:1197518" } } } , 18131 { 18132 type comment , 18133 version 0 , 18134 source { 18135 { 18136 src { 18137 db "Ensembl" , 18138 tag 18139 str "" } , 18140 url "http://www.ensembl.org/Mus_musculus/contigview?geneid=BC052 18141323" } } } , 18142 { 18143 type comment , 18144 version 0 , 18145 source { 18146 { 18147 src { 18148 db "UCSC" , 18149 tag 18150 str "" } , 18151 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position= 18152BC052323" } } } , 18153 { 18154 type comment , 18155 version 0 , 18156 source { 18157 { 18158 src { 18159 db "MGC" , 18160 tag 18161 str "BC080846" } , 18162 anchor "MGC" , 18163 url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Mm&LIST=BC080846" } } } } } , 18164 { 18165 type generif , 18166 text "Expression of AATYK mRNA and protein increased during postnatal 18167 brain development. In immature granule cells, overexpression of AATYK 18168 promoted neurite outgrowth; a tyrosine kinase-defective mutant significantly 18169 inhibited it." , 18170 version 0 , 18171 refs { 18172 pmid 12670708 } , 18173 create-date 18174 str "Jun 17 2003 12:00AM" , 18175 update-date 18176 str "Aug 3 2003 7:06AM" } } , 18177 unique-keys { 18178 { 18179 db "LocusID" , 18180 tag 18181 id 11302 } , 18182 { 18183 db "MGI" , 18184 tag 18185 id 1197518 } } , 18186 xtra-index-terms { 18187 "LOC11302" } } 18188Entrezgene ::= { 18189 track-info { 18190 geneid 11303 , 18191 status live , 18192 create-date 18193 std { 18194 year 2003 , 18195 month 8 , 18196 day 28 , 18197 hour 21 , 18198 minute 39 , 18199 second 0 } , 18200 update-date 18201 std { 18202 year 2005 , 18203 month 4 , 18204 day 19 , 18205 hour 12 , 18206 minute 12 , 18207 second 0 } } , 18208 type protein-coding , 18209 source { 18210 genome genomic , 18211 origin natural , 18212 org { 18213 taxname "Mus musculus" , 18214 common "house mouse" , 18215 db { 18216 { 18217 db "taxon" , 18218 tag 18219 id 10090 } } , 18220 syn { 18221 "mouse" } , 18222 orgname { 18223 name 18224 binomial { 18225 genus "Mus" , 18226 species "musculus" } , 18227 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 18228 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 18229 Sciurognathi; Muridae; Murinae; Mus" , 18230 gcode 1 , 18231 mgcode 2 , 18232 div "ROD" } } , 18233 subtype { 18234 { 18235 subtype chromosome , 18236 name "4" } } } , 18237 gene { 18238 locus "Abca1" , 18239 desc "ATP-binding cassette, sub-family A (ABC1), member 1" , 18240 maploc "4 23.1 cM" , 18241 syn { 18242 "Abc1" } , 18243 locus-tag "MGI:99607" } , 18244 prot { 18245 name { 18246 "ATP-binding cassette 1, sub-family A, member 1" , 18247 "ATP-binding cassette 1" } } , 18248 summary "The membrane-associated protein encoded by this gene is a member of 18249 the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins 18250 transport various molecules across extra- and intracellular membranes. ABC 18251 genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, 18252 OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members 18253 of the ABC1 subfamily comprise the only major ABC subfamily found exclusively 18254 in multicellular eukaryotes. In humans, this protein functions as a 18255 cholesterol efflux pump in the cellular lipid removal pathway. Mutations in 18256 the human gene have been associated with Tangier's disease and familial 18257 high-density lipoprotein deficiency." , 18258 location { 18259 { 18260 display-str "4 A5-B3" , 18261 method 18262 map-type cyto } , 18263 { 18264 display-str "4 23.1 cM" , 18265 method 18266 map-type cM } } , 18267 gene-source { 18268 src "LocusLink" , 18269 src-int 11303 , 18270 src-str2 "11303" , 18271 gene-display FALSE , 18272 locus-display FALSE , 18273 extra-terms FALSE } , 18274 locus { 18275 { 18276 type genomic , 18277 heading "Reference" , 18278 accession "NC_000070" , 18279 version 1 , 18280 seqs { 18281 int { 18282 from 52275832 , 18283 to 52404936 , 18284 strand minus , 18285 id 18286 gi 51860768 } } , 18287 products { 18288 { 18289 type mRNA , 18290 heading "Reference" , 18291 accession "NM_013454" , 18292 version 2 , 18293 genomic-coords { 18294 mix { 18295 int { 18296 from 52275832 , 18297 to 52279127 , 18298 strand minus , 18299 id 18300 gi 51860768 } , 18301 int { 18302 from 52280381 , 18303 to 52280624 , 18304 strand minus , 18305 id 18306 gi 51860768 } , 18307 int { 18308 from 52281306 , 18309 to 52281398 , 18310 strand minus , 18311 id 18312 gi 51860768 } , 18313 int { 18314 from 52281917 , 18315 to 52282020 , 18316 strand minus , 18317 id 18318 gi 51860768 } , 18319 int { 18320 from 52283201 , 18321 to 52283335 , 18322 strand minus , 18323 id 18324 gi 51860768 } , 18325 int { 18326 from 52283663 , 18327 to 52283804 , 18328 strand minus , 18329 id 18330 gi 51860768 } , 18331 int { 18332 from 52285763 , 18333 to 52285869 , 18334 strand minus , 18335 id 18336 gi 51860768 } , 18337 int { 18338 from 52286583 , 18339 to 52286645 , 18340 strand minus , 18341 id 18342 gi 51860768 } , 18343 int { 18344 from 52287358 , 18345 to 52287478 , 18346 strand minus , 18347 id 18348 gi 51860768 } , 18349 int { 18350 from 52287708 , 18351 to 52287837 , 18352 strand minus , 18353 id 18354 gi 51860768 } , 18355 int { 18356 from 52289159 , 18357 to 52289282 , 18358 strand minus , 18359 id 18360 gi 51860768 } , 18361 int { 18362 from 52290819 , 18363 to 52290963 , 18364 strand minus , 18365 id 18366 gi 51860768 } , 18367 int { 18368 from 52291074 , 18369 to 52291189 , 18370 strand minus , 18371 id 18372 gi 51860768 } , 18373 int { 18374 from 52294000 , 18375 to 52294177 , 18376 strand minus , 18377 id 18378 gi 51860768 } , 18379 int { 18380 from 52295333 , 18381 to 52295502 , 18382 strand minus , 18383 id 18384 gi 51860768 } , 18385 int { 18386 from 52295979 , 18387 to 52296053 , 18388 strand minus , 18389 id 18390 gi 51860768 } , 18391 int { 18392 from 52304301 , 18393 to 52304406 , 18394 strand minus , 18395 id 18396 gi 51860768 } , 18397 int { 18398 from 52305377 , 18399 to 52305409 , 18400 strand minus , 18401 id 18402 gi 51860768 } , 18403 int { 18404 from 52306531 , 18405 to 52306625 , 18406 strand minus , 18407 id 18408 gi 51860768 } , 18409 int { 18410 from 52307434 , 18411 to 52307623 , 18412 strand minus , 18413 id 18414 gi 51860768 } , 18415 int { 18416 from 52310945 , 18417 to 52311043 , 18418 strand minus , 18419 id 18420 gi 51860768 } , 18421 int { 18422 from 52312075 , 18423 to 52312199 , 18424 strand minus , 18425 id 18426 gi 51860768 } , 18427 int { 18428 from 52313731 , 18429 to 52313879 , 18430 strand minus , 18431 id 18432 gi 51860768 } , 18433 int { 18434 from 52314836 , 18435 to 52314949 , 18436 strand minus , 18437 id 18438 gi 51860768 } , 18439 int { 18440 from 52315120 , 18441 to 52315168 , 18442 strand minus , 18443 id 18444 gi 51860768 } , 18445 int { 18446 from 52316867 , 18447 to 52317069 , 18448 strand minus , 18449 id 18450 gi 51860768 } , 18451 int { 18452 from 52317942 , 18453 to 52318014 , 18454 strand minus , 18455 id 18456 gi 51860768 } , 18457 int { 18458 from 52319264 , 18459 to 52319484 , 18460 strand minus , 18461 id 18462 gi 51860768 } , 18463 int { 18464 from 52320175 , 18465 to 52320312 , 18466 strand minus , 18467 id 18468 gi 51860768 } , 18469 int { 18470 from 52320491 , 18471 to 52320633 , 18472 strand minus , 18473 id 18474 gi 51860768 } , 18475 int { 18476 from 52321935 , 18477 to 52322066 , 18478 strand minus , 18479 id 18480 gi 51860768 } , 18481 int { 18482 from 52322987 , 18483 to 52323158 , 18484 strand minus , 18485 id 18486 gi 51860768 } , 18487 int { 18488 from 52324615 , 18489 to 52324728 , 18490 strand minus , 18491 id 18492 gi 51860768 } , 18493 int { 18494 from 52325810 , 18495 to 52326014 , 18496 strand minus , 18497 id 18498 gi 51860768 } , 18499 int { 18500 from 52326966 , 18501 to 52327187 , 18502 strand minus , 18503 id 18504 gi 51860768 } , 18505 int { 18506 from 52328761 , 18507 to 52328983 , 18508 strand minus , 18509 id 18510 gi 51860768 } , 18511 int { 18512 from 52329428 , 18513 to 52329604 , 18514 strand minus , 18515 id 18516 gi 51860768 } , 18517 int { 18518 from 52330140 , 18519 to 52330345 , 18520 strand minus , 18521 id 18522 gi 51860768 } , 18523 int { 18524 from 52331037 , 18525 to 52331234 , 18526 strand minus , 18527 id 18528 gi 51860768 } , 18529 int { 18530 from 52334843 , 18531 to 52334959 , 18532 strand minus , 18533 id 18534 gi 51860768 } , 18535 int { 18536 from 52335298 , 18537 to 52335437 , 18538 strand minus , 18539 id 18540 gi 51860768 } , 18541 int { 18542 from 52337773 , 18543 to 52338013 , 18544 strand minus , 18545 id 18546 gi 51860768 } , 18547 int { 18548 from 52340629 , 18549 to 52340721 , 18550 strand minus , 18551 id 18552 gi 51860768 } , 18553 int { 18554 from 52352050 , 18555 to 52352226 , 18556 strand minus , 18557 id 18558 gi 51860768 } , 18559 int { 18560 from 52354208 , 18561 to 52354329 , 18562 strand minus , 18563 id 18564 gi 51860768 } , 18565 int { 18566 from 52372641 , 18567 to 52372759 , 18568 strand minus , 18569 id 18570 gi 51860768 } , 18571 int { 18572 from 52373765 , 18573 to 52373906 , 18574 strand minus , 18575 id 18576 gi 51860768 } , 18577 int { 18578 from 52377966 , 18579 to 52378059 , 18580 strand minus , 18581 id 18582 gi 51860768 } , 18583 int { 18584 from 52388974 , 18585 to 52389139 , 18586 strand minus , 18587 id 18588 gi 51860768 } , 18589 int { 18590 from 52404720 , 18591 to 52404936 , 18592 strand minus , 18593 id 18594 gi 51860768 } } } , 18595 seqs { 18596 whole 18597 gi 34577068 } , 18598 products { 18599 { 18600 type peptide , 18601 heading "Reference" , 18602 accession "NP_038482" , 18603 version 2 , 18604 genomic-coords { 18605 packed-int { 18606 { 18607 from 52278987 , 18608 to 52279127 , 18609 strand minus , 18610 id 18611 gi 51860768 } , 18612 { 18613 from 52280381 , 18614 to 52280624 , 18615 strand minus , 18616 id 18617 gi 51860768 } , 18618 { 18619 from 52281306 , 18620 to 52281398 , 18621 strand minus , 18622 id 18623 gi 51860768 } , 18624 { 18625 from 52281917 , 18626 to 52282020 , 18627 strand minus , 18628 id 18629 gi 51860768 } , 18630 { 18631 from 52283201 , 18632 to 52283335 , 18633 strand minus , 18634 id 18635 gi 51860768 } , 18636 { 18637 from 52283663 , 18638 to 52283804 , 18639 strand minus , 18640 id 18641 gi 51860768 } , 18642 { 18643 from 52285763 , 18644 to 52285869 , 18645 strand minus , 18646 id 18647 gi 51860768 } , 18648 { 18649 from 52286583 , 18650 to 52286645 , 18651 strand minus , 18652 id 18653 gi 51860768 } , 18654 { 18655 from 52287358 , 18656 to 52287478 , 18657 strand minus , 18658 id 18659 gi 51860768 } , 18660 { 18661 from 52287708 , 18662 to 52287837 , 18663 strand minus , 18664 id 18665 gi 51860768 } , 18666 { 18667 from 52289159 , 18668 to 52289282 , 18669 strand minus , 18670 id 18671 gi 51860768 } , 18672 { 18673 from 52290819 , 18674 to 52290963 , 18675 strand minus , 18676 id 18677 gi 51860768 } , 18678 { 18679 from 52291074 , 18680 to 52291189 , 18681 strand minus , 18682 id 18683 gi 51860768 } , 18684 { 18685 from 52294000 , 18686 to 52294177 , 18687 strand minus , 18688 id 18689 gi 51860768 } , 18690 { 18691 from 52295333 , 18692 to 52295502 , 18693 strand minus , 18694 id 18695 gi 51860768 } , 18696 { 18697 from 52295979 , 18698 to 52296053 , 18699 strand minus , 18700 id 18701 gi 51860768 } , 18702 { 18703 from 52304301 , 18704 to 52304406 , 18705 strand minus , 18706 id 18707 gi 51860768 } , 18708 { 18709 from 52305377 , 18710 to 52305409 , 18711 strand minus , 18712 id 18713 gi 51860768 } , 18714 { 18715 from 52306531 , 18716 to 52306625 , 18717 strand minus , 18718 id 18719 gi 51860768 } , 18720 { 18721 from 52307434 , 18722 to 52307623 , 18723 strand minus , 18724 id 18725 gi 51860768 } , 18726 { 18727 from 52310945 , 18728 to 52311043 , 18729 strand minus , 18730 id 18731 gi 51860768 } , 18732 { 18733 from 52312075 , 18734 to 52312199 , 18735 strand minus , 18736 id 18737 gi 51860768 } , 18738 { 18739 from 52313731 , 18740 to 52313879 , 18741 strand minus , 18742 id 18743 gi 51860768 } , 18744 { 18745 from 52314836 , 18746 to 52314949 , 18747 strand minus , 18748 id 18749 gi 51860768 } , 18750 { 18751 from 52315120 , 18752 to 52315168 , 18753 strand minus , 18754 id 18755 gi 51860768 } , 18756 { 18757 from 52316867 , 18758 to 52317069 , 18759 strand minus , 18760 id 18761 gi 51860768 } , 18762 { 18763 from 52317942 , 18764 to 52318014 , 18765 strand minus , 18766 id 18767 gi 51860768 } , 18768 { 18769 from 52319264 , 18770 to 52319484 , 18771 strand minus , 18772 id 18773 gi 51860768 } , 18774 { 18775 from 52320175 , 18776 to 52320312 , 18777 strand minus , 18778 id 18779 gi 51860768 } , 18780 { 18781 from 52320491 , 18782 to 52320633 , 18783 strand minus , 18784 id 18785 gi 51860768 } , 18786 { 18787 from 52321935 , 18788 to 52322066 , 18789 strand minus , 18790 id 18791 gi 51860768 } , 18792 { 18793 from 52322987 , 18794 to 52323158 , 18795 strand minus , 18796 id 18797 gi 51860768 } , 18798 { 18799 from 52324615 , 18800 to 52324728 , 18801 strand minus , 18802 id 18803 gi 51860768 } , 18804 { 18805 from 52325810 , 18806 to 52326014 , 18807 strand minus , 18808 id 18809 gi 51860768 } , 18810 { 18811 from 52326966 , 18812 to 52327187 , 18813 strand minus , 18814 id 18815 gi 51860768 } , 18816 { 18817 from 52328761 , 18818 to 52328983 , 18819 strand minus , 18820 id 18821 gi 51860768 } , 18822 { 18823 from 52329428 , 18824 to 52329604 , 18825 strand minus , 18826 id 18827 gi 51860768 } , 18828 { 18829 from 52330140 , 18830 to 52330345 , 18831 strand minus , 18832 id 18833 gi 51860768 } , 18834 { 18835 from 52331037 , 18836 to 52331234 , 18837 strand minus , 18838 id 18839 gi 51860768 } , 18840 { 18841 from 52334843 , 18842 to 52334959 , 18843 strand minus , 18844 id 18845 gi 51860768 } , 18846 { 18847 from 52335298 , 18848 to 52335437 , 18849 strand minus , 18850 id 18851 gi 51860768 } , 18852 { 18853 from 52337773 , 18854 to 52338013 , 18855 strand minus , 18856 id 18857 gi 51860768 } , 18858 { 18859 from 52340629 , 18860 to 52340721 , 18861 strand minus , 18862 id 18863 gi 51860768 } , 18864 { 18865 from 52352050 , 18866 to 52352226 , 18867 strand minus , 18868 id 18869 gi 51860768 } , 18870 { 18871 from 52354208 , 18872 to 52354329 , 18873 strand minus , 18874 id 18875 gi 51860768 } , 18876 { 18877 from 52372641 , 18878 to 52372759 , 18879 strand minus , 18880 id 18881 gi 51860768 } , 18882 { 18883 from 52373765 , 18884 to 52373906 , 18885 strand minus , 18886 id 18887 gi 51860768 } , 18888 { 18889 from 52377966 , 18890 to 52378059 , 18891 strand minus , 18892 id 18893 gi 51860768 } , 18894 { 18895 from 52388974 , 18896 to 52389039 , 18897 strand minus , 18898 id 18899 gi 51860768 } } } , 18900 seqs { 18901 whole 18902 gi 34577069 } } } } } } , 18903 { 18904 type genomic , 18905 heading "Reference" , 18906 accession "NT_039260" , 18907 version 3 , 18908 seqs { 18909 int { 18910 from 26554540 , 18911 to 26683644 , 18912 strand minus , 18913 id 18914 gi 51709342 } } , 18915 products { 18916 { 18917 type mRNA , 18918 heading "Reference" , 18919 accession "NM_013454" , 18920 version 2 , 18921 genomic-coords { 18922 mix { 18923 int { 18924 from 26554540 , 18925 to 26557835 , 18926 strand minus , 18927 id 18928 gi 51709342 } , 18929 int { 18930 from 26559089 , 18931 to 26559332 , 18932 strand minus , 18933 id 18934 gi 51709342 } , 18935 int { 18936 from 26560014 , 18937 to 26560106 , 18938 strand minus , 18939 id 18940 gi 51709342 } , 18941 int { 18942 from 26560625 , 18943 to 26560728 , 18944 strand minus , 18945 id 18946 gi 51709342 } , 18947 int { 18948 from 26561909 , 18949 to 26562043 , 18950 strand minus , 18951 id 18952 gi 51709342 } , 18953 int { 18954 from 26562371 , 18955 to 26562512 , 18956 strand minus , 18957 id 18958 gi 51709342 } , 18959 int { 18960 from 26564471 , 18961 to 26564577 , 18962 strand minus , 18963 id 18964 gi 51709342 } , 18965 int { 18966 from 26565291 , 18967 to 26565353 , 18968 strand minus , 18969 id 18970 gi 51709342 } , 18971 int { 18972 from 26566066 , 18973 to 26566186 , 18974 strand minus , 18975 id 18976 gi 51709342 } , 18977 int { 18978 from 26566416 , 18979 to 26566545 , 18980 strand minus , 18981 id 18982 gi 51709342 } , 18983 int { 18984 from 26567867 , 18985 to 26567990 , 18986 strand minus , 18987 id 18988 gi 51709342 } , 18989 int { 18990 from 26569527 , 18991 to 26569671 , 18992 strand minus , 18993 id 18994 gi 51709342 } , 18995 int { 18996 from 26569782 , 18997 to 26569897 , 18998 strand minus , 18999 id 19000 gi 51709342 } , 19001 int { 19002 from 26572708 , 19003 to 26572885 , 19004 strand minus , 19005 id 19006 gi 51709342 } , 19007 int { 19008 from 26574041 , 19009 to 26574210 , 19010 strand minus , 19011 id 19012 gi 51709342 } , 19013 int { 19014 from 26574687 , 19015 to 26574761 , 19016 strand minus , 19017 id 19018 gi 51709342 } , 19019 int { 19020 from 26583009 , 19021 to 26583114 , 19022 strand minus , 19023 id 19024 gi 51709342 } , 19025 int { 19026 from 26584085 , 19027 to 26584117 , 19028 strand minus , 19029 id 19030 gi 51709342 } , 19031 int { 19032 from 26585239 , 19033 to 26585333 , 19034 strand minus , 19035 id 19036 gi 51709342 } , 19037 int { 19038 from 26586142 , 19039 to 26586331 , 19040 strand minus , 19041 id 19042 gi 51709342 } , 19043 int { 19044 from 26589653 , 19045 to 26589751 , 19046 strand minus , 19047 id 19048 gi 51709342 } , 19049 int { 19050 from 26590783 , 19051 to 26590907 , 19052 strand minus , 19053 id 19054 gi 51709342 } , 19055 int { 19056 from 26592439 , 19057 to 26592587 , 19058 strand minus , 19059 id 19060 gi 51709342 } , 19061 int { 19062 from 26593544 , 19063 to 26593657 , 19064 strand minus , 19065 id 19066 gi 51709342 } , 19067 int { 19068 from 26593828 , 19069 to 26593876 , 19070 strand minus , 19071 id 19072 gi 51709342 } , 19073 int { 19074 from 26595575 , 19075 to 26595777 , 19076 strand minus , 19077 id 19078 gi 51709342 } , 19079 int { 19080 from 26596650 , 19081 to 26596722 , 19082 strand minus , 19083 id 19084 gi 51709342 } , 19085 int { 19086 from 26597972 , 19087 to 26598192 , 19088 strand minus , 19089 id 19090 gi 51709342 } , 19091 int { 19092 from 26598883 , 19093 to 26599020 , 19094 strand minus , 19095 id 19096 gi 51709342 } , 19097 int { 19098 from 26599199 , 19099 to 26599341 , 19100 strand minus , 19101 id 19102 gi 51709342 } , 19103 int { 19104 from 26600643 , 19105 to 26600774 , 19106 strand minus , 19107 id 19108 gi 51709342 } , 19109 int { 19110 from 26601695 , 19111 to 26601866 , 19112 strand minus , 19113 id 19114 gi 51709342 } , 19115 int { 19116 from 26603323 , 19117 to 26603436 , 19118 strand minus , 19119 id 19120 gi 51709342 } , 19121 int { 19122 from 26604518 , 19123 to 26604722 , 19124 strand minus , 19125 id 19126 gi 51709342 } , 19127 int { 19128 from 26605674 , 19129 to 26605895 , 19130 strand minus , 19131 id 19132 gi 51709342 } , 19133 int { 19134 from 26607469 , 19135 to 26607691 , 19136 strand minus , 19137 id 19138 gi 51709342 } , 19139 int { 19140 from 26608136 , 19141 to 26608312 , 19142 strand minus , 19143 id 19144 gi 51709342 } , 19145 int { 19146 from 26608848 , 19147 to 26609053 , 19148 strand minus , 19149 id 19150 gi 51709342 } , 19151 int { 19152 from 26609745 , 19153 to 26609942 , 19154 strand minus , 19155 id 19156 gi 51709342 } , 19157 int { 19158 from 26613551 , 19159 to 26613667 , 19160 strand minus , 19161 id 19162 gi 51709342 } , 19163 int { 19164 from 26614006 , 19165 to 26614145 , 19166 strand minus , 19167 id 19168 gi 51709342 } , 19169 int { 19170 from 26616481 , 19171 to 26616721 , 19172 strand minus , 19173 id 19174 gi 51709342 } , 19175 int { 19176 from 26619337 , 19177 to 26619429 , 19178 strand minus , 19179 id 19180 gi 51709342 } , 19181 int { 19182 from 26630758 , 19183 to 26630934 , 19184 strand minus , 19185 id 19186 gi 51709342 } , 19187 int { 19188 from 26632916 , 19189 to 26633037 , 19190 strand minus , 19191 id 19192 gi 51709342 } , 19193 int { 19194 from 26651349 , 19195 to 26651467 , 19196 strand minus , 19197 id 19198 gi 51709342 } , 19199 int { 19200 from 26652473 , 19201 to 26652614 , 19202 strand minus , 19203 id 19204 gi 51709342 } , 19205 int { 19206 from 26656674 , 19207 to 26656767 , 19208 strand minus , 19209 id 19210 gi 51709342 } , 19211 int { 19212 from 26667682 , 19213 to 26667847 , 19214 strand minus , 19215 id 19216 gi 51709342 } , 19217 int { 19218 from 26683428 , 19219 to 26683644 , 19220 strand minus , 19221 id 19222 gi 51709342 } } } , 19223 seqs { 19224 whole 19225 gi 34577068 } , 19226 products { 19227 { 19228 type peptide , 19229 heading "Reference" , 19230 accession "NP_038482" , 19231 version 2 , 19232 genomic-coords { 19233 packed-int { 19234 { 19235 from 26557695 , 19236 to 26557835 , 19237 strand minus , 19238 id 19239 gi 51709342 } , 19240 { 19241 from 26559089 , 19242 to 26559332 , 19243 strand minus , 19244 id 19245 gi 51709342 } , 19246 { 19247 from 26560014 , 19248 to 26560106 , 19249 strand minus , 19250 id 19251 gi 51709342 } , 19252 { 19253 from 26560625 , 19254 to 26560728 , 19255 strand minus , 19256 id 19257 gi 51709342 } , 19258 { 19259 from 26561909 , 19260 to 26562043 , 19261 strand minus , 19262 id 19263 gi 51709342 } , 19264 { 19265 from 26562371 , 19266 to 26562512 , 19267 strand minus , 19268 id 19269 gi 51709342 } , 19270 { 19271 from 26564471 , 19272 to 26564577 , 19273 strand minus , 19274 id 19275 gi 51709342 } , 19276 { 19277 from 26565291 , 19278 to 26565353 , 19279 strand minus , 19280 id 19281 gi 51709342 } , 19282 { 19283 from 26566066 , 19284 to 26566186 , 19285 strand minus , 19286 id 19287 gi 51709342 } , 19288 { 19289 from 26566416 , 19290 to 26566545 , 19291 strand minus , 19292 id 19293 gi 51709342 } , 19294 { 19295 from 26567867 , 19296 to 26567990 , 19297 strand minus , 19298 id 19299 gi 51709342 } , 19300 { 19301 from 26569527 , 19302 to 26569671 , 19303 strand minus , 19304 id 19305 gi 51709342 } , 19306 { 19307 from 26569782 , 19308 to 26569897 , 19309 strand minus , 19310 id 19311 gi 51709342 } , 19312 { 19313 from 26572708 , 19314 to 26572885 , 19315 strand minus , 19316 id 19317 gi 51709342 } , 19318 { 19319 from 26574041 , 19320 to 26574210 , 19321 strand minus , 19322 id 19323 gi 51709342 } , 19324 { 19325 from 26574687 , 19326 to 26574761 , 19327 strand minus , 19328 id 19329 gi 51709342 } , 19330 { 19331 from 26583009 , 19332 to 26583114 , 19333 strand minus , 19334 id 19335 gi 51709342 } , 19336 { 19337 from 26584085 , 19338 to 26584117 , 19339 strand minus , 19340 id 19341 gi 51709342 } , 19342 { 19343 from 26585239 , 19344 to 26585333 , 19345 strand minus , 19346 id 19347 gi 51709342 } , 19348 { 19349 from 26586142 , 19350 to 26586331 , 19351 strand minus , 19352 id 19353 gi 51709342 } , 19354 { 19355 from 26589653 , 19356 to 26589751 , 19357 strand minus , 19358 id 19359 gi 51709342 } , 19360 { 19361 from 26590783 , 19362 to 26590907 , 19363 strand minus , 19364 id 19365 gi 51709342 } , 19366 { 19367 from 26592439 , 19368 to 26592587 , 19369 strand minus , 19370 id 19371 gi 51709342 } , 19372 { 19373 from 26593544 , 19374 to 26593657 , 19375 strand minus , 19376 id 19377 gi 51709342 } , 19378 { 19379 from 26593828 , 19380 to 26593876 , 19381 strand minus , 19382 id 19383 gi 51709342 } , 19384 { 19385 from 26595575 , 19386 to 26595777 , 19387 strand minus , 19388 id 19389 gi 51709342 } , 19390 { 19391 from 26596650 , 19392 to 26596722 , 19393 strand minus , 19394 id 19395 gi 51709342 } , 19396 { 19397 from 26597972 , 19398 to 26598192 , 19399 strand minus , 19400 id 19401 gi 51709342 } , 19402 { 19403 from 26598883 , 19404 to 26599020 , 19405 strand minus , 19406 id 19407 gi 51709342 } , 19408 { 19409 from 26599199 , 19410 to 26599341 , 19411 strand minus , 19412 id 19413 gi 51709342 } , 19414 { 19415 from 26600643 , 19416 to 26600774 , 19417 strand minus , 19418 id 19419 gi 51709342 } , 19420 { 19421 from 26601695 , 19422 to 26601866 , 19423 strand minus , 19424 id 19425 gi 51709342 } , 19426 { 19427 from 26603323 , 19428 to 26603436 , 19429 strand minus , 19430 id 19431 gi 51709342 } , 19432 { 19433 from 26604518 , 19434 to 26604722 , 19435 strand minus , 19436 id 19437 gi 51709342 } , 19438 { 19439 from 26605674 , 19440 to 26605895 , 19441 strand minus , 19442 id 19443 gi 51709342 } , 19444 { 19445 from 26607469 , 19446 to 26607691 , 19447 strand minus , 19448 id 19449 gi 51709342 } , 19450 { 19451 from 26608136 , 19452 to 26608312 , 19453 strand minus , 19454 id 19455 gi 51709342 } , 19456 { 19457 from 26608848 , 19458 to 26609053 , 19459 strand minus , 19460 id 19461 gi 51709342 } , 19462 { 19463 from 26609745 , 19464 to 26609942 , 19465 strand minus , 19466 id 19467 gi 51709342 } , 19468 { 19469 from 26613551 , 19470 to 26613667 , 19471 strand minus , 19472 id 19473 gi 51709342 } , 19474 { 19475 from 26614006 , 19476 to 26614145 , 19477 strand minus , 19478 id 19479 gi 51709342 } , 19480 { 19481 from 26616481 , 19482 to 26616721 , 19483 strand minus , 19484 id 19485 gi 51709342 } , 19486 { 19487 from 26619337 , 19488 to 26619429 , 19489 strand minus , 19490 id 19491 gi 51709342 } , 19492 { 19493 from 26630758 , 19494 to 26630934 , 19495 strand minus , 19496 id 19497 gi 51709342 } , 19498 { 19499 from 26632916 , 19500 to 26633037 , 19501 strand minus , 19502 id 19503 gi 51709342 } , 19504 { 19505 from 26651349 , 19506 to 26651467 , 19507 strand minus , 19508 id 19509 gi 51709342 } , 19510 { 19511 from 26652473 , 19512 to 26652614 , 19513 strand minus , 19514 id 19515 gi 51709342 } , 19516 { 19517 from 26656674 , 19518 to 26656767 , 19519 strand minus , 19520 id 19521 gi 51709342 } , 19522 { 19523 from 26667682 , 19524 to 26667747 , 19525 strand minus , 19526 id 19527 gi 51709342 } } } , 19528 seqs { 19529 whole 19530 gi 34577069 } } } } } } } , 19531 properties { 19532 { 19533 type comment , 19534 label "Nomenclature" , 19535 version 0 , 19536 source { 19537 { 19538 anchor "Mouse Genome Informatics" } } , 19539 properties { 19540 { 19541 type property , 19542 label "Official Symbol" , 19543 text "Abca1" , 19544 version 0 } , 19545 { 19546 type property , 19547 label "Official Full Name" , 19548 text "ATP-binding cassette, sub-family A (ABC1), member 1" , 19549 version 0 } } } , 19550 { 19551 type comment , 19552 heading "GeneOntology" , 19553 version 0 , 19554 source { 19555 { 19556 pre-text "Provided by" , 19557 anchor "MGI" , 19558 url "http://www.informatics.jax.org/" } } , 19559 comment { 19560 { 19561 type comment , 19562 label "Function" , 19563 version 0 , 19564 comment { 19565 { 19566 type comment , 19567 version 0 , 19568 source { 19569 { 19570 src { 19571 db "GO" , 19572 tag 19573 id 5524 } , 19574 anchor "ATP binding" , 19575 post-text "evidence: IEA" } } } , 19576 { 19577 type comment , 19578 version 0 , 19579 source { 19580 { 19581 src { 19582 db "GO" , 19583 tag 19584 id 16887 } , 19585 anchor "ATPase activity" , 19586 post-text "evidence: IEA" } } } } } , 19587 { 19588 type comment , 19589 label "Process" , 19590 version 0 , 19591 comment { 19592 { 19593 type comment , 19594 version 0 , 19595 refs { 19596 pmid 11559713 } , 19597 source { 19598 { 19599 src { 19600 db "GO" , 19601 tag 19602 id 8203 } , 19603 anchor "cholesterol metabolism" , 19604 post-text "evidence: IDA" } } } , 19605 { 19606 type comment , 19607 version 0 , 19608 refs { 19609 pmid 11559713 } , 19610 source { 19611 { 19612 src { 19613 db "GO" , 19614 tag 19615 id 30301 } , 19616 anchor "cholesterol transport" , 19617 post-text "evidence: IDA" } } } , 19618 { 19619 type comment , 19620 version 0 , 19621 refs { 19622 pmid 12859204 } , 19623 source { 19624 { 19625 src { 19626 db "GO" , 19627 tag 19628 id 42158 } , 19629 anchor "lipoprotein biosynthesis" , 19630 post-text "evidence: IMP" } } } , 19631 { 19632 type comment , 19633 version 0 , 19634 refs { 19635 pmid 10878804 } , 19636 source { 19637 { 19638 src { 19639 db "GO" , 19640 tag 19641 id 6911 } , 19642 anchor "phagocytosis, engulfment" , 19643 post-text "evidence: IMP" } } } , 19644 { 19645 type comment , 19646 version 0 , 19647 refs { 19648 pmid 10878804 } , 19649 source { 19650 { 19651 src { 19652 db "GO" , 19653 tag 19654 id 45332 } , 19655 anchor "phospholipid translocation" , 19656 post-text "evidence: IMP" } } } , 19657 { 19658 type comment , 19659 version 0 , 19660 source { 19661 { 19662 src { 19663 db "GO" , 19664 tag 19665 id 6810 } , 19666 anchor "transport" , 19667 post-text "evidence: IEA" } } } } } , 19668 { 19669 type comment , 19670 label "Component" , 19671 version 0 , 19672 comment { 19673 { 19674 type comment , 19675 version 0 , 19676 refs { 19677 pmid 10878804 } , 19678 source { 19679 { 19680 src { 19681 db "GO" , 19682 tag 19683 id 5794 } , 19684 anchor "Golgi apparatus" , 19685 post-text "evidence: IDA" } } } , 19686 { 19687 type comment , 19688 version 0 , 19689 refs { 19690 pmid 12466851 } , 19691 source { 19692 { 19693 src { 19694 db "GO" , 19695 tag 19696 id 16021 } , 19697 anchor "integral to membrane" , 19698 post-text "evidence: TAS" } } } , 19699 { 19700 type comment , 19701 version 0 , 19702 refs { 19703 pmid 10878804 } , 19704 source { 19705 { 19706 src { 19707 db "GO" , 19708 tag 19709 id 5887 } , 19710 anchor "integral to plasma membrane" , 19711 post-text "evidence: IDA" } } } , 19712 { 19713 type comment , 19714 version 0 , 19715 refs { 19716 pmid 10878804 } , 19717 source { 19718 { 19719 src { 19720 db "GO" , 19721 tag 19722 id 43231 } , 19723 anchor "intracellular membrane-bound organelle" , 19724 post-text "evidence: IDA" } } } } } } } } , 19725 homology { 19726 { 19727 type comment , 19728 heading "Human, Rat" , 19729 version 0 , 19730 source { 19731 { 19732 src { 19733 db "HomoloGene" , 19734 tag 19735 id 21130 } , 19736 anchor "Map Viewer" , 19737 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=4& 19738MAPS=genes-r-org/human-chr/mouse%3A4,genes-r-org/rat-chr/mouse%3A4,genes-r-org 19739/mouse-chr4&query=e%3A11303[id]+AND+gene[obj_type]&QSTR=abca1&cmd=focus&fill=1 197400" } } } } , 19741 comments { 19742 { 19743 type comment , 19744 heading "LocusTagLink" , 19745 version 0 , 19746 source { 19747 { 19748 src { 19749 db "MGI" , 19750 tag 19751 id 99607 } } } } , 19752 { 19753 type comment , 19754 heading "RefSeq Status" , 19755 label "REVIEWED" , 19756 version 0 } , 19757 { 19758 type comment , 19759 version 0 , 19760 refs { 19761 pmid 15632021 , 19762 pmid 15269218 , 19763 pmid 15269217 , 19764 pmid 15163665 , 19765 pmid 15051721 , 19766 pmid 15033469 , 19767 pmid 15026428 , 19768 pmid 14993246 , 19769 pmid 14729855 , 19770 pmid 14726413 , 19771 pmid 14722086 , 19772 pmid 14703508 , 19773 pmid 14560020 , 19774 pmid 14559902 , 19775 pmid 12928428 , 19776 pmid 12897186 , 19777 pmid 12897148 , 19778 pmid 12859204 , 19779 pmid 12777468 , 19780 pmid 12754274 , 19781 pmid 12615679 , 19782 pmid 12586783 , 19783 pmid 12576511 , 19784 pmid 12551894 , 19785 pmid 12547832 , 19786 pmid 12511593 , 19787 pmid 12488454 , 19788 pmid 12487373 , 19789 pmid 12466851 , 19790 pmid 12384498 , 19791 pmid 12215451 , 19792 pmid 12196520 , 19793 pmid 12151852 , 19794 pmid 12105210 , 19795 pmid 12050168 , 19796 pmid 11972062 , 19797 pmid 11909955 , 19798 pmid 11896206 , 19799 pmid 11893753 , 19800 pmid 11752403 , 19801 pmid 11741998 , 19802 pmid 11559713 , 19803 pmid 11352567 , 19804 pmid 11217851 , 19805 pmid 11076861 , 19806 pmid 11042159 , 19807 pmid 10878804 , 19808 pmid 10760292 , 19809 pmid 10655069 , 19810 pmid 10581369 , 19811 pmid 10349636 , 19812 pmid 8889548 , 19813 pmid 8088782 , 19814 pmid 7774911 } } , 19815 { 19816 type comment , 19817 heading "Markers (Sequence Tagged Sites/STS)" , 19818 version 0 , 19819 comment { 19820 { 19821 type comment , 19822 version 0 , 19823 source { 19824 { 19825 src { 19826 db "UniSTS" , 19827 tag 19828 id 179001 } , 19829 anchor "X75926" , 19830 post-text "(e-PCR)" } } , 19831 comment { 19832 { 19833 type other , 19834 label "Alternate name" , 19835 text "3512" , 19836 version 0 } , 19837 { 19838 type other , 19839 label "Alternate name" , 19840 text "ND" , 19841 version 0 } } } , 19842 { 19843 type comment , 19844 version 0 , 19845 source { 19846 { 19847 src { 19848 db "UniSTS" , 19849 tag 19850 id 271599 } , 19851 anchor "PMC16657P1" , 19852 post-text "(e-PCR)" } } } , 19853 { 19854 type comment , 19855 version 0 , 19856 source { 19857 { 19858 src { 19859 db "UniSTS" , 19860 tag 19861 id 271951 } , 19862 anchor "PMC207565P1" , 19863 post-text "(e-PCR)" } } } } } , 19864 { 19865 type comment , 19866 heading "NCBI Reference Sequences (RefSeq)" , 19867 version 0 , 19868 products { 19869 { 19870 type mRNA , 19871 heading "mRNA Sequence" , 19872 accession "NM_013454" , 19873 version 2 , 19874 source { 19875 { 19876 src { 19877 db "Nucleotide" , 19878 tag 19879 id 34577068 } , 19880 anchor "NM_013454" } } , 19881 seqs { 19882 whole 19883 gi 34577068 } , 19884 products { 19885 { 19886 type peptide , 19887 heading "Product" , 19888 accession "NP_038482" , 19889 version 2 , 19890 source { 19891 { 19892 src { 19893 db "Protein" , 19894 tag 19895 id 34577069 } , 19896 anchor "NP_038482" , 19897 post-text "ATP-binding cassette 1, sub-family A, member 1" } } , 19898 seqs { 19899 whole 19900 gi 34577069 } , 19901 comment { 19902 { 19903 type other , 19904 heading "Conserved Domains" , 19905 version 0 , 19906 source { 19907 { 19908 src { 19909 db "PROT_CDD" , 19910 tag 19911 id 34577069 } , 19912 pre-text "(3)" , 19913 anchor "summary" } } , 19914 comment { 19915 { 19916 type other , 19917 version 0 , 19918 source { 19919 { 19920 src { 19921 db "CDD" , 19922 tag 19923 id 5341 } , 19924 anchor "cd00267: ABC_ATPase; ABC (ATP-binding 19925 cassette) transporter nucleotide-binding domain" } } , 19926 comment { 19927 { 19928 type other , 19929 text "Location: 899 - 1114 Blast Score: 462" , 19930 version 0 } , 19931 { 19932 type other , 19933 text "Location: 1912 - 2121 Blast Score: 356" , 19934 version 0 } } } , 19935 { 19936 type other , 19937 version 0 , 19938 source { 19939 { 19940 src { 19941 db "CDD" , 19942 tag 19943 id 13428 } , 19944 anchor "COG4152: COG4152; ABC-type uncharacterized 19945 transport system, ATPase component [General function prediction only]" } } , 19946 comment { 19947 { 19948 type other , 19949 text "Location: 1912 - 2218 Blast Score: 360" , 19950 version 0 } } } } } } } } , 19951 comment { 19952 { 19953 type other , 19954 heading "Source Sequence" , 19955 version 0 , 19956 source { 19957 { 19958 src { 19959 db "Nucleotide" , 19960 tag 19961 str "AK045442,BB657864,CA885568,X75926" } , 19962 anchor "AK045442,BB657864,CA885568,X75926" } } , 19963 comment { 19964 { 19965 type other , 19966 version 0 } } } } } } } , 19967 { 19968 type comment , 19969 heading "Related Sequences" , 19970 version 0 , 19971 products { 19972 { 19973 type genomic , 19974 heading "Genomic" , 19975 accession "AF287263" , 19976 version 1 , 19977 source { 19978 { 19979 src { 19980 db "Nucleotide" , 19981 tag 19982 id 11611824 } , 19983 anchor "AF287263" } } , 19984 seqs { 19985 whole 19986 gi 11611824 } , 19987 products { 19988 { 19989 type peptide , 19990 accession "AAG39073" , 19991 version 1 , 19992 source { 19993 { 19994 src { 19995 db "Protein" , 19996 tag 19997 id 11611825 } , 19998 anchor "AAG39073" } } , 19999 seqs { 20000 whole 20001 gi 11611825 } } } , 20002 comment { 20003 { 20004 type other , 20005 label "Strain" , 20006 text "C57BL/6J" , 20007 version 0 } } } , 20008 { 20009 type mRNA , 20010 heading "mRNA" , 20011 accession "AK019548" , 20012 version 1 , 20013 source { 20014 { 20015 src { 20016 db "Nucleotide" , 20017 tag 20018 id 12859824 } , 20019 anchor "AK019548" } } , 20020 seqs { 20021 whole 20022 gi 12859824 } , 20023 products { 20024 { 20025 type peptide , 20026 text "None" , 20027 version 0 } } , 20028 comment { 20029 { 20030 type other , 20031 label "Strain" , 20032 text "C57BL/6J" , 20033 version 0 } } } , 20034 { 20035 type mRNA , 20036 heading "mRNA" , 20037 accession "AK045442" , 20038 version 1 , 20039 source { 20040 { 20041 src { 20042 db "Nucleotide" , 20043 tag 20044 id 26090897 } , 20045 anchor "AK045442" } } , 20046 seqs { 20047 whole 20048 gi 26090897 } , 20049 products { 20050 { 20051 type peptide , 20052 text "None" , 20053 version 0 } } , 20054 comment { 20055 { 20056 type other , 20057 label "Strain" , 20058 text "C57BL/6J" , 20059 version 0 } } } , 20060 { 20061 type mRNA , 20062 heading "mRNA" , 20063 accession "AK051920" , 20064 version 1 , 20065 source { 20066 { 20067 src { 20068 db "Nucleotide" , 20069 tag 20070 id 26342297 } , 20071 anchor "AK051920" } } , 20072 seqs { 20073 whole 20074 gi 26342297 } , 20075 products { 20076 { 20077 type peptide , 20078 accession "BAC34811" , 20079 version 1 , 20080 source { 20081 { 20082 src { 20083 db "Protein" , 20084 tag 20085 id 26342298 } , 20086 anchor "BAC34811" } } , 20087 seqs { 20088 whole 20089 gi 26342298 } } } , 20090 comment { 20091 { 20092 type other , 20093 label "Strain" , 20094 text "C57BL/6J" , 20095 version 0 } } } , 20096 { 20097 type mRNA , 20098 heading "mRNA" , 20099 accession "BB657864" , 20100 version 1 , 20101 source { 20102 { 20103 src { 20104 db "Nucleotide" , 20105 tag 20106 id 16491690 } , 20107 anchor "BB657864" } } , 20108 seqs { 20109 whole 20110 gi 16491690 } , 20111 products { 20112 { 20113 type peptide , 20114 text "None" , 20115 version 0 } } } , 20116 { 20117 type mRNA , 20118 heading "mRNA" , 20119 accession "CA885568" , 20120 version 1 , 20121 source { 20122 { 20123 src { 20124 db "Nucleotide" , 20125 tag 20126 id 27337117 } , 20127 anchor "CA885568" } } , 20128 seqs { 20129 whole 20130 gi 27337117 } , 20131 products { 20132 { 20133 type peptide , 20134 text "None" , 20135 version 0 } } , 20136 comment { 20137 { 20138 type other , 20139 label "Strain" , 20140 text "CD-1" , 20141 version 0 } } } , 20142 { 20143 type mRNA , 20144 heading "mRNA" , 20145 accession "X75926" , 20146 version 1 , 20147 source { 20148 { 20149 src { 20150 db "Nucleotide" , 20151 tag 20152 id 495256 } , 20153 anchor "X75926" } } , 20154 seqs { 20155 whole 20156 gi 495256 } , 20157 products { 20158 { 20159 type peptide , 20160 accession "CAA53530" , 20161 version 1 , 20162 source { 20163 { 20164 src { 20165 db "Protein" , 20166 tag 20167 id 495257 } , 20168 anchor "CAA53530" } } , 20169 seqs { 20170 whole 20171 gi 495257 } } } , 20172 comment { 20173 { 20174 type other , 20175 label "Strain" , 20176 text "DBA/2" , 20177 version 0 } } } , 20178 { 20179 type other , 20180 text "None" , 20181 version 0 , 20182 products { 20183 { 20184 type peptide , 20185 accession "P41233" , 20186 version 0 , 20187 source { 20188 { 20189 src { 20190 db "Protein" , 20191 tag 20192 id 51338775 } , 20193 anchor "P41233" } } , 20194 seqs { 20195 whole 20196 gi 51338775 } } } } } } , 20197 { 20198 type comment , 20199 heading "Additional Links" , 20200 version 0 , 20201 comment { 20202 { 20203 type comment , 20204 version 0 , 20205 source { 20206 { 20207 src { 20208 db "Evidence Viewer" , 20209 tag 20210 str "11303" } , 20211 anchor "Evidence Viewer" , 20212 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont 20213ig=NT_039260.3&gene=Abca1&lid=11303&from=26554541&to=26683645" } } } , 20214 { 20215 type comment , 20216 version 0 , 20217 source { 20218 { 20219 src { 20220 db "ModelMaker" , 20221 tag 20222 str "11303" } , 20223 anchor "ModelMaker" , 20224 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10 20225090&contig=NT_039260.3&gene=Abca1&lid=11303" } } } , 20226 { 20227 type comment , 20228 text "UniGene" , 20229 version 0 , 20230 xtra-properties { 20231 { 20232 tag "UNIGENE" , 20233 value "Mm.277376" } } , 20234 source { 20235 { 20236 src { 20237 db "UniGene" , 20238 tag 20239 str "Mm.277376" } , 20240 anchor "Mm.277376" , 20241 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=27 202427376" } } } , 20243 { 20244 type comment , 20245 version 0 , 20246 source { 20247 { 20248 src { 20249 db "HomoloGene" , 20250 tag 20251 str "11303" } , 20252 anchor "HomoloGene" , 20253 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 2025411303[loc]&TAXID=10090" } } } , 20255 { 20256 type comment , 20257 version 0 , 20258 source { 20259 { 20260 src { 20261 db "MGI" , 20262 tag 20263 id 99607 } , 20264 anchor "MGI" , 20265 url "http://www.informatics.jax.org/searches/accession_report.cg 20266i?id=MGI:99607" } } } , 20267 { 20268 type comment , 20269 version 0 , 20270 source { 20271 { 20272 src { 20273 db "Ensembl" , 20274 tag 20275 str "" } , 20276 url "http://www.ensembl.org/Mus_musculus/contigview?geneid=X7592 202776" } } } , 20278 { 20279 type comment , 20280 version 0 , 20281 source { 20282 { 20283 src { 20284 db "UCSC" , 20285 tag 20286 str "" } , 20287 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position= 20288X75926" } } } , 20289 { 20290 type comment , 20291 text "Gene Expression Database (GXD) at MGI" , 20292 version 0 , 20293 source { 20294 { 20295 src { 20296 db "Gene Expression Database (GXD) at MGI" , 20297 tag 20298 str "MGI:99607" } , 20299 anchor "MGI:99607" , 20300 url "http://www.informatics.jax.org/searches/expression_report.c 20301gi?id=MGI:99607" } } } , 20302 { 20303 type comment , 20304 text "Human ABC-Transporter Proteins" , 20305 version 0 , 20306 source { 20307 { 20308 src { 20309 db "Human ABC-Transporter Proteins" , 20310 tag 20311 str "Human ABC-Transporter Proteins" } , 20312 anchor "Human ABC-Transporter Proteins" , 20313 url "http://nutrigene.4t.com/humanabc.htm" } } } } } , 20314 { 20315 type generif , 20316 text "Gene deletion protects aginst cerebral malaria from Plasmodium 20317 berghei." , 20318 version 0 , 20319 refs { 20320 pmid 15632021 } , 20321 create-date 20322 str "Mar 7 2005 7:07PM" , 20323 update-date 20324 str "Mar 8 2005 3:26AM" } , 20325 { 20326 type generif , 20327 text "ABCA1-dependent cholesterol mobilization to apoA-I increased new 20328 cholesterol synthesis, indicating depletion of the regulatory pool of 20329 hepatocyte cholesterol during HDL formation" , 20330 version 0 , 20331 refs { 20332 pmid 14993246 } , 20333 create-date 20334 str "Mar 7 2005 7:07PM" , 20335 update-date 20336 str "Mar 8 2005 12:40AM" } , 20337 { 20338 type generif , 20339 text "a 21% decrease (P = 0.01) in fertility was observed between 20340 ABCA1(-/-) males compared with WT controls across their reproductive 20341 lifespans" , 20342 version 0 , 20343 refs { 20344 pmid 15026428 } , 20345 create-date 20346 str "Mar 7 2005 7:07PM" , 20347 update-date 20348 str "Mar 7 2005 9:28PM" } , 20349 { 20350 type generif , 20351 text "Verapamil increases ABCA1 expression through LXR-independent 20352 mechanism and thereby increases apoA-I-mediated cellular lipid release and 20353 production of HDL." , 20354 version 0 , 20355 refs { 20356 pmid 14726413 } , 20357 create-date 20358 str "Jan 8 2005 10:01AM" , 20359 update-date 20360 str "Jan 8 2005 2:49PM" } , 20361 { 20362 type generif , 20363 text "In murine macrophage cell line RAW264 cells, cAMP induced 20364 expression of ABCA1, release of cellular phospholipid and cholesterol by 20365 apoA-I, and reversible binding of apoA-I to the cell." , 20366 version 0 , 20367 refs { 20368 pmid 14729855 } , 20369 create-date 20370 str "Dec 4 2004 10:01AM" , 20371 update-date 20372 str "Dec 4 2004 2:26PM" } , 20373 { 20374 type generif , 20375 text "The time course and temperature dependence of ABCA1-mediated lipid 20376 efflux to apoA-I support a role for endocytosis in this process" , 20377 version 0 , 20378 refs { 20379 pmid 14703508 } , 20380 create-date 20381 str "Dec 4 2004 10:01AM" , 20382 update-date 20383 str "Dec 4 2004 11:09AM" } , 20384 { 20385 type generif , 20386 text "conclude that intact ATP binding cassette transporter A1 (ABCA1) 20387 function is necessary for proper maturation of dense bodies in platelets" , 20388 version 0 , 20389 refs { 20390 pmid 15163665 } , 20391 create-date 20392 str "Oct 30 2004 10:01AM" , 20393 update-date 20394 str "Oct 30 2004 10:58AM" } , 20395 { 20396 type generif , 20397 text "glial ABCA1 has a key role in apoE metabolism in the brain" , 20398 version 0 , 20399 refs { 20400 pmid 15269218 } , 20401 create-date 20402 str "Oct 30 2004 10:01AM" , 20403 update-date 20404 str "Oct 30 2004 10:43AM" } , 20405 { 20406 type generif , 20407 text "ABCA1 plays a critical role in central nervous system apoE 20408 metabolism" , 20409 version 0 , 20410 refs { 20411 pmid 15269217 } , 20412 create-date 20413 str "Oct 30 2004 10:01AM" , 20414 update-date 20415 str "Oct 30 2004 10:43AM" } , 20416 { 20417 type generif , 20418 text "PPAR alpha influences cholesterol absorption through modulating 20419 the ATP binding cassette transporter A1 activity in the intestine by a 20420 mechanism involving liver X receptor alpha" , 20421 version 0 , 20422 refs { 20423 pmid 12897186 } , 20424 create-date 20425 str "Aug 9 2004 1:01PM" , 20426 update-date 20427 str "Aug 9 2004 1:41PM" } , 20428 { 20429 type generif , 20430 text "When endotoxin or cytokines (tumor necrosis factor and 20431 interleukin-1) were incubated with J774 murine macrophages, the mRNA levels 20432 of ABCA1 were decreased." , 20433 version 0 , 20434 refs { 20435 pmid 12777468 } , 20436 create-date 20437 str "Jul 12 2004 11:39AM" , 20438 update-date 20439 str "Jul 12 2004 12:16PM" } , 20440 { 20441 type generif , 20442 text "ABCA1 is stabilized by a specific structural element possessing a 20443 linear array of acidic residues spanning two apoA-I amphipathic alpha-helices" , 20444 version 0 , 20445 refs { 20446 pmid 15051721 } , 20447 create-date 20448 str "Jul 12 2004 11:39AM" , 20449 update-date 20450 str "Jul 12 2004 11:52AM" } , 20451 { 20452 type generif , 20453 text "despite large induction of ABCA1 mRNA during differentiation, 20454 cholesterol efflux through the ABCA1 pathway remains limited in adipocytes 20455 and requires prolonged lipolysis" , 20456 version 0 , 20457 refs { 20458 pmid 12754274 } , 20459 create-date 20460 str "Jun 23 2004 4:43PM" , 20461 update-date 20462 str "Jun 23 2004 5:25PM" } , 20463 { 20464 type generif , 20465 text "ABCA1 turnover is modulated by alpha1-syntrophin" , 20466 version 0 , 20467 refs { 20468 pmid 14722086 } , 20469 create-date 20470 str "Jun 14 2004 4:41PM" , 20471 update-date 20472 str "Jun 14 2004 5:46PM" } , 20473 { 20474 type generif , 20475 text "Review. ABCA1-deficient mice are used to demonstrate the relation 20476 between ABCA1 expression, cellular lipid efflux, & HDL metabolism. The 20477 ABCA1-deficient mouse phenotype parallels that of human Tangier disease." , 20478 version 0 , 20479 refs { 20480 pmid 12615679 } , 20481 create-date 20482 str "Jan 25 2004 12:00AM" , 20483 update-date 20484 str "Feb 29 2004 7:03AM" } , 20485 { 20486 type generif , 20487 text "cellular ATP-binding cassette transporter A1 has a role in 20488 transporting cholesterol and phospholipids from cells to lipoprotein 20489 particles by a process involving PLTP interactions" , 20490 version 0 , 20491 refs { 20492 pmid 14559902 } , 20493 create-date 20494 str "Jan 20 2004 12:00AM" , 20495 update-date 20496 str "Feb 15 2004 6:35PM" } , 20497 { 20498 type generif , 20499 text "Results demonstrate that ABCA1 plays a key role in hepatic 20500 cholesterol efflux, inducing pathways that modulate cholesterol homeostasis 20501 in the liver, and establish the liver as a major source of plasma HDL-C." , 20502 version 0 , 20503 refs { 20504 pmid 12576511 } , 20505 create-date 20506 str "Jan 5 2004 12:00AM" , 20507 update-date 20508 str "Feb 29 2004 7:03AM" } , 20509 { 20510 type generif , 20511 text "ABCA1-mediated vesicle release involves lipid raft plasma membrane 20512 domains" , 20513 version 0 , 20514 refs { 20515 pmid 12928428 } , 20516 create-date 20517 str "Nov 30 2003 12:00AM" , 20518 update-date 20519 str "Jan 4 2004 7:03AM" } , 20520 { 20521 type generif , 20522 text "These studies indicate a direct role of retinoic acid receptor 20523 gamma/retinoid x receptor in induction of macrophage ABCA1." , 20524 version 0 , 20525 refs { 20526 pmid 14560020 } , 20527 create-date 20528 str "Nov 17 2003 12:00AM" , 20529 update-date 20530 str "Dec 7 2003 7:05AM" } , 20531 { 20532 type generif , 20533 text "As observed in knockout mice, ABCA1 is necessary for the adequate 20534 lipidation of apoAI, which enables the interaction with LCAT and subsequent 20535 maturation." , 20536 version 0 , 20537 refs { 20538 pmid 12859204 } , 20539 create-date 20540 str "Sep 30 2003 12:00AM" , 20541 update-date 20542 str "Oct 12 2003 7:03AM" } , 20543 { 20544 type generif , 20545 text "ABCA1 and SREBP1 are regulated by liver X receptor/corepressor 20546 complexes" , 20547 version 0 , 20548 refs { 20549 pmid 12897148 } , 20550 create-date 20551 str "Aug 25 2003 12:00AM" , 20552 update-date 20553 str "Aug 31 2003 7:04AM" } , 20554 { 20555 type generif , 20556 text "Estrogen's antiatherogenic effects may occur via ABCA1-mediated 20557 pathway, and circulating HDL levels may influence expression of ABCA1" , 20558 version 0 , 20559 refs { 20560 pmid 12487373 } , 20561 create-date 20562 str "Jun 3 2003 12:00AM" , 20563 update-date 20564 str "Jun 8 2003 7:28AM" } , 20565 { 20566 type generif , 20567 text "Hepatocyte expression of ABCA1 is central to the lipidation of 20568 newly synthesized apoA-I but also contributes to the lipidation of exogenous 20569 apoA-I." , 20570 version 0 , 20571 refs { 20572 pmid 12547832 } , 20573 create-date 20574 str "Apr 2 2003 12:00AM" , 20575 update-date 20576 str "May 11 2003 7:05AM" } , 20577 { 20578 type generif , 20579 text "Golgi is involved in ABCA1-mediated cholesterol efflux." , 20580 version 0 , 20581 refs { 20582 pmid 12551894 } , 20583 create-date 20584 str "Apr 1 2003 12:00AM" , 20585 update-date 20586 str "May 11 2003 7:05AM" } , 20587 { 20588 type generif , 20589 text "ATP-binding cassette transporter A1 (ABCA1)-mediated lipid efflux 20590 is promoted by central helices of ApoA-I; amino acid residues 220-231 of the 20591 wild-type ApoA-I are required for lipid efflux and high density lipoprotein 20592 formation" , 20593 version 0 , 20594 refs { 20595 pmid 12488454 } , 20596 create-date 20597 str "Mar 20 2003 12:00AM" , 20598 update-date 20599 str "Apr 13 2003 7:04AM" } , 20600 { 20601 type generif , 20602 text "annexin I is externalized from pituitary folliculo-stellate cells 20603 by an ABC transporter and the ATP binding cassette transporter A1 is a likely 20604 candidate" , 20605 version 0 , 20606 refs { 20607 pmid 12586783 } , 20608 create-date 20609 str "Mar 19 2003 12:00AM" , 20610 update-date 20611 str "Mar 31 2003 6:34AM" } , 20612 { 20613 type generif , 20614 text "ATP-binding-cassette transporter A1 gene expression in macrophages 20615 is downregulated by statins" , 20616 version 0 , 20617 refs { 20618 pmid 15033469 } , 20619 create-date 20620 str "Apr 26 2004 12:00AM" , 20621 update-date 20622 str "May 23 2004 7:05AM" } , 20623 { 20624 type generif , 20625 text "ABCA1 is regulated by PEST sequence-mediated calpain proteolysis 20626 that appears to be reversed by apolipoprotein-mediated phospholipid efflux" , 20627 version 0 , 20628 refs { 20629 pmid 12511593 } , 20630 create-date 20631 str "Feb 7 2003 12:00AM" , 20632 update-date 20633 str "Mar 9 2003 7:04AM" } , 20634 { 20635 type generif , 20636 text "REVIEW: ATP-binding cassette transporter A1 and cholesterol 20637 trafficking" , 20638 version 0 , 20639 refs { 20640 pmid 12151852 } , 20641 create-date 20642 str "Jan 24 2003 12:00AM" , 20643 update-date 20644 str "Feb 2 2003 7:50AM" } , 20645 { 20646 type generif , 20647 text "mediates cholesterol efflux and is defective in free 20648 cholesterol-loaded macrophages; mechanism involves enhanced degradation and 20649 full npc1 activity." , 20650 version 0 , 20651 refs { 20652 pmid 12215451 } , 20653 create-date 20654 str "Jan 16 2003 12:00AM" , 20655 update-date 20656 str "Feb 9 2003 7:14AM" } , 20657 { 20658 type generif , 20659 text "induction as a result of liver X receptor agonism increases 20660 secreted Abeta levels" , 20661 version 0 , 20662 refs { 20663 pmid 12384498 } , 20664 create-date 20665 str "Jan 9 2003 12:00AM" , 20666 update-date 20667 str "Feb 2 2003 7:50AM" } , 20668 { 20669 type generif , 20670 text "Increased hepatobiliary and fecal cholesterol excretion upon 20671 activation of the liver X receptor is independent of ABCA1." , 20672 version 0 , 20673 refs { 20674 pmid 12105210 } , 20675 create-date 20676 str "Nov 20 2002 12:00AM" , 20677 update-date 20678 str "Feb 2 2003 7:50AM" } , 20679 { 20680 type generif , 20681 text "A novel serine (Ser-2054) on the ABCA1 protein crucial for PKA 20682 phosphorylation and for regulation of ABCA1 transporter activity." , 20683 version 0 , 20684 refs { 20685 pmid 12196520 } , 20686 create-date 20687 str "Nov 16 2002 12:00AM" , 20688 update-date 20689 str "Feb 2 2003 7:50AM" } , 20690 { 20691 type generif , 20692 text "studies establish a novel binding site for apoA-I on the 20693 macrophage extracellular matrix that may function together with ABCA1 in 20694 promoting cholesterol efflux" , 20695 version 0 , 20696 refs { 20697 pmid 12050168 } , 20698 create-date 20699 str "Sep 27 2002 12:00AM" , 20700 update-date 20701 str "Feb 2 2003 7:49AM" } , 20702 { 20703 type generif , 20704 text "Role as a phosphatidylserine translocase" , 20705 version 0 , 20706 refs { 20707 pmid 11893753 } , 20708 create-date 20709 str "Jul 8 2002 12:00AM" , 20710 update-date 20711 str "Jul 22 2002 5:59AM" } , 20712 { 20713 type generif , 20714 text "Leukocyte ABCA1 controls susceptibility to atherosclerosis and 20715 macrophage recruitment into tissues" , 20716 version 0 , 20717 refs { 20718 pmid 11972062 } , 20719 create-date 20720 str "May 31 2002 12:00AM" , 20721 update-date 20722 str "Jun 15 2002 8:10AM" } , 20723 { 20724 type generif , 20725 text "Conditional disruption of the peroxisome proliferator-activated 20726 receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, 20727 and apoE in macrophages and reduced cholesterol efflux." , 20728 version 0 , 20729 refs { 20730 pmid 11909955 } , 20731 create-date 20732 str "Apr 16 2002 12:00AM" , 20733 update-date 20734 str "Apr 28 2002 6:21PM" } , 20735 { 20736 type generif , 20737 text "in the presence of apoE, overexpression of ABCA1 modulates HDL as 20738 well as apoB-containing lipoprotein metabolism and reduces atherosclerosis in 20739 vivo" , 20740 version 0 , 20741 refs { 20742 pmid 11752403 } , 20743 create-date 20744 str "Apr 2 2002 12:00AM" , 20745 update-date 20746 str "Apr 28 2002 6:21PM" } , 20747 { 20748 type generif , 20749 text "ABCA1 is expressed in a pattern consistent with its role in HDL-C 20750 metabolism" , 20751 version 0 , 20752 refs { 20753 pmid 11896206 } , 20754 create-date 20755 str "Mar 27 2002 12:00AM" , 20756 update-date 20757 str "Apr 8 2002 3:24PM" } , 20758 { 20759 type generif , 20760 text "unsaturated fatty acids reduce the macrophage ABCA1 content by 20761 enhancing its degradation rate" , 20762 version 0 , 20763 refs { 20764 pmid 11741998 } , 20765 create-date 20766 str "Mar 5 2002 12:00AM" , 20767 update-date 20768 str "Apr 1 2002 5:34AM" } , 20769 { 20770 type comment , 20771 heading "Alleles" , 20772 version 0 , 20773 comment { 20774 { 20775 type comment , 20776 text "The following allele types are documented at Mouse Genome 20777 Informatics" , 20778 version 0 , 20779 source { 20780 { 20781 anchor "(MGI)" , 20782 url "http://www.informatics.jax.org/searches/allele_report.cgi?m 20783arkerID=MGI:99607" } } } , 20784 { 20785 type comment , 20786 heading "Targeted (knock-out) (2)" , 20787 version 0 , 20788 refs { 20789 pmid 10760292 , 20790 pmid 10980140 } } } } } , 20791 unique-keys { 20792 { 20793 db "LocusID" , 20794 tag 20795 id 11303 } , 20796 { 20797 db "MGI" , 20798 tag 20799 id 99607 } } , 20800 xtra-index-terms { 20801 "LOC11303" } } 20802Entrezgene ::= { 20803 track-info { 20804 geneid 11304 , 20805 status live , 20806 create-date 20807 std { 20808 year 2003 , 20809 month 8 , 20810 day 28 , 20811 hour 21 , 20812 minute 39 , 20813 second 0 } , 20814 update-date 20815 std { 20816 year 2005 , 20817 month 4 , 20818 day 15 , 20819 hour 9 , 20820 minute 44 , 20821 second 0 } } , 20822 type protein-coding , 20823 source { 20824 genome genomic , 20825 origin natural , 20826 org { 20827 taxname "Mus musculus" , 20828 common "house mouse" , 20829 db { 20830 { 20831 db "taxon" , 20832 tag 20833 id 10090 } } , 20834 syn { 20835 "mouse" } , 20836 orgname { 20837 name 20838 binomial { 20839 genus "Mus" , 20840 species "musculus" } , 20841 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 20842 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 20843 Sciurognathi; Muridae; Murinae; Mus" , 20844 gcode 1 , 20845 mgcode 2 , 20846 div "ROD" } } , 20847 subtype { 20848 { 20849 subtype chromosome , 20850 name "3" } } } , 20851 gene { 20852 locus "Abca4" , 20853 desc "ATP-binding cassette, sub-family A (ABC1), member 4" , 20854 maploc "3 61.8 cM" , 20855 syn { 20856 "RmP" , 20857 "Abcr" , 20858 "Abc10" , 20859 "D430003I15Rik" } , 20860 locus-tag "MGI:109424" } , 20861 prot { 20862 name { 20863 "ATP-binding cassette, sub-family A, member 4" , 20864 "Rim protein" , 20865 "ATP-binding cassette 10" } } , 20866 summary "The membrane-associated protein encoded by this gene is a member of 20867 the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins 20868 transport various molecules across extra- and intracellular membranes. ABC 20869 genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, 20870 OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members 20871 of the ABC1 subfamily comprise the only major ABC subfamily found exclusively 20872 in multicellular eukaryotes. This protein was the first of the ABC 20873 transporters to be observed in photoreceptors and may play a role in the 20874 photoresponse. Mutations in the human gene are found in patients diagnosed 20875 with Stargardt disease and are associated with retinitis pigmentosa-19 and 20876 macular degeneration age-related 2." , 20877 location { 20878 { 20879 display-str "3 G1" , 20880 method 20881 map-type cyto } , 20882 { 20883 display-str "3 61.8 cM" , 20884 method 20885 map-type cM } } , 20886 gene-source { 20887 src "LocusLink" , 20888 src-int 11304 , 20889 src-str2 "11304" , 20890 gene-display FALSE , 20891 locus-display FALSE , 20892 extra-terms FALSE } , 20893 locus { 20894 { 20895 type genomic , 20896 heading "Reference" , 20897 accession "NC_000069" , 20898 version 1 , 20899 seqs { 20900 int { 20901 from 122426366 , 20902 to 122561663 , 20903 strand plus , 20904 id 20905 gi 51860767 } } , 20906 products { 20907 { 20908 type mRNA , 20909 heading "Reference" , 20910 accession "NM_007378" , 20911 version 1 , 20912 genomic-coords { 20913 mix { 20914 int { 20915 from 122426366 , 20916 to 122426518 , 20917 strand plus , 20918 id 20919 gi 51860767 } , 20920 int { 20921 from 122434867 , 20922 to 122434960 , 20923 strand plus , 20924 id 20925 gi 51860767 } , 20926 int { 20927 from 122436157 , 20928 to 122436298 , 20929 strand plus , 20930 id 20931 gi 51860767 } , 20932 int { 20933 from 122437283 , 20934 to 122437422 , 20935 strand plus , 20936 id 20937 gi 51860767 } , 20938 int { 20939 from 122444741 , 20940 to 122444868 , 20941 strand plus , 20942 id 20943 gi 51860767 } , 20944 int { 20945 from 122451134 , 20946 to 122451331 , 20947 strand plus , 20948 id 20949 gi 51860767 } , 20950 int { 20951 from 122462504 , 20952 to 122462593 , 20953 strand plus , 20954 id 20955 gi 51860767 } , 20956 int { 20957 from 122465447 , 20958 to 122465687 , 20959 strand plus , 20960 id 20961 gi 51860767 } , 20962 int { 20963 from 122467129 , 20964 to 122467268 , 20965 strand plus , 20966 id 20967 gi 51860767 } , 20968 int { 20969 from 122468154 , 20970 to 122468270 , 20971 strand plus , 20972 id 20973 gi 51860767 } , 20974 int { 20975 from 122468889 , 20976 to 122469086 , 20977 strand plus , 20978 id 20979 gi 51860767 } , 20980 int { 20981 from 122484278 , 20982 to 122484483 , 20983 strand plus , 20984 id 20985 gi 51860767 } , 20986 int { 20987 from 122485037 , 20988 to 122485213 , 20989 strand plus , 20990 id 20991 gi 51860767 } , 20992 int { 20993 from 122486910 , 20994 to 122487132 , 20995 strand plus , 20996 id 20997 gi 51860767 } , 20998 int { 20999 from 122492064 , 21000 to 122492285 , 21001 strand plus , 21002 id 21003 gi 51860767 } , 21004 int { 21005 from 122493968 , 21006 to 122494172 , 21007 strand plus , 21008 id 21009 gi 51860767 } , 21010 int { 21011 from 122498257 , 21012 to 122498322 , 21013 strand plus , 21014 id 21015 gi 51860767 } , 21016 int { 21017 from 122501632 , 21018 to 122501721 , 21019 strand plus , 21020 id 21021 gi 51860767 } , 21022 int { 21023 from 122503233 , 21024 to 122503407 , 21025 strand plus , 21026 id 21027 gi 51860767 } , 21028 int { 21029 from 122505161 , 21030 to 122505292 , 21031 strand plus , 21032 id 21033 gi 51860767 } , 21034 int { 21035 from 122507723 , 21036 to 122507862 , 21037 strand plus , 21038 id 21039 gi 51860767 } , 21040 int { 21041 from 122508424 , 21042 to 122508561 , 21043 strand plus , 21044 id 21045 gi 51860767 } , 21046 int { 21047 from 122509727 , 21048 to 122509920 , 21049 strand plus , 21050 id 21051 gi 51860767 } , 21052 int { 21053 from 122510918 , 21054 to 122511002 , 21055 strand plus , 21056 id 21057 gi 51860767 } , 21058 int { 21059 from 122514126 , 21060 to 122514331 , 21061 strand plus , 21062 id 21063 gi 51860767 } , 21064 int { 21065 from 122514655 , 21066 to 122514703 , 21067 strand plus , 21068 id 21069 gi 51860767 } , 21070 int { 21071 from 122516604 , 21072 to 122516866 , 21073 strand plus , 21074 id 21075 gi 51860767 } , 21076 int { 21077 from 122518583 , 21078 to 122518707 , 21079 strand plus , 21080 id 21081 gi 51860767 } , 21082 int { 21083 from 122519172 , 21084 to 122519270 , 21085 strand plus , 21086 id 21087 gi 51860767 } , 21088 int { 21089 from 122520026 , 21090 to 122520212 , 21091 strand plus , 21092 id 21093 gi 51860767 } , 21094 int { 21095 from 122523293 , 21096 to 122523387 , 21097 strand plus , 21098 id 21099 gi 51860767 } , 21100 int { 21101 from 122525002 , 21102 to 122525034 , 21103 strand plus , 21104 id 21105 gi 51860767 } , 21106 int { 21107 from 122528800 , 21108 to 122528905 , 21109 strand plus , 21110 id 21111 gi 51860767 } , 21112 int { 21113 from 122529033 , 21114 to 122529107 , 21115 strand plus , 21116 id 21117 gi 51860767 } , 21118 int { 21119 from 122529332 , 21120 to 122529501 , 21121 strand plus , 21122 id 21123 gi 51860767 } , 21124 int { 21125 from 122530477 , 21126 to 122530654 , 21127 strand plus , 21128 id 21129 gi 51860767 } , 21130 int { 21131 from 122536879 , 21132 to 122536994 , 21133 strand plus , 21134 id 21135 gi 51860767 } , 21136 int { 21137 from 122537940 , 21138 to 122538087 , 21139 strand plus , 21140 id 21141 gi 51860767 } , 21142 int { 21143 from 122539437 , 21144 to 122539560 , 21145 strand plus , 21146 id 21147 gi 51860767 } , 21148 int { 21149 from 122539916 , 21150 to 122540045 , 21151 strand plus , 21152 id 21153 gi 51860767 } , 21154 int { 21155 from 122543903 , 21156 to 122544023 , 21157 strand plus , 21158 id 21159 gi 51860767 } , 21160 int { 21161 from 122544463 , 21162 to 122544525 , 21163 strand plus , 21164 id 21165 gi 51860767 } , 21166 int { 21167 from 122545390 , 21168 to 122545496 , 21169 strand plus , 21170 id 21171 gi 51860767 } , 21172 int { 21173 from 122548250 , 21174 to 122548391 , 21175 strand plus , 21176 id 21177 gi 51860767 } , 21178 int { 21179 from 122551495 , 21180 to 122551629 , 21181 strand plus , 21182 id 21183 gi 51860767 } , 21184 int { 21185 from 122552344 , 21186 to 122552447 , 21187 strand plus , 21188 id 21189 gi 51860767 } , 21190 int { 21191 from 122552531 , 21192 to 122552623 , 21193 strand plus , 21194 id 21195 gi 51860767 } , 21196 int { 21197 from 122555381 , 21198 to 122555630 , 21199 strand plus , 21200 id 21201 gi 51860767 } , 21202 int { 21203 from 122557676 , 21204 to 122557762 , 21205 strand plus , 21206 id 21207 gi 51860767 } , 21208 int { 21209 from 122561316 , 21210 to 122561663 , 21211 strand plus , 21212 id 21213 gi 51860767 } } } , 21214 seqs { 21215 whole 21216 gi 6671494 } , 21217 products { 21218 { 21219 type peptide , 21220 heading "Reference" , 21221 accession "NP_031404" , 21222 version 1 , 21223 genomic-coords { 21224 packed-int { 21225 { 21226 from 122426453 , 21227 to 122426518 , 21228 strand plus , 21229 id 21230 gi 51860767 } , 21231 { 21232 from 122434867 , 21233 to 122434960 , 21234 strand plus , 21235 id 21236 gi 51860767 } , 21237 { 21238 from 122436157 , 21239 to 122436298 , 21240 strand plus , 21241 id 21242 gi 51860767 } , 21243 { 21244 from 122437283 , 21245 to 122437422 , 21246 strand plus , 21247 id 21248 gi 51860767 } , 21249 { 21250 from 122444741 , 21251 to 122444868 , 21252 strand plus , 21253 id 21254 gi 51860767 } , 21255 { 21256 from 122451134 , 21257 to 122451331 , 21258 strand plus , 21259 id 21260 gi 51860767 } , 21261 { 21262 from 122462504 , 21263 to 122462593 , 21264 strand plus , 21265 id 21266 gi 51860767 } , 21267 { 21268 from 122465447 , 21269 to 122465687 , 21270 strand plus , 21271 id 21272 gi 51860767 } , 21273 { 21274 from 122467129 , 21275 to 122467268 , 21276 strand plus , 21277 id 21278 gi 51860767 } , 21279 { 21280 from 122468154 , 21281 to 122468270 , 21282 strand plus , 21283 id 21284 gi 51860767 } , 21285 { 21286 from 122468889 , 21287 to 122469086 , 21288 strand plus , 21289 id 21290 gi 51860767 } , 21291 { 21292 from 122484278 , 21293 to 122484483 , 21294 strand plus , 21295 id 21296 gi 51860767 } , 21297 { 21298 from 122485037 , 21299 to 122485213 , 21300 strand plus , 21301 id 21302 gi 51860767 } , 21303 { 21304 from 122486910 , 21305 to 122487132 , 21306 strand plus , 21307 id 21308 gi 51860767 } , 21309 { 21310 from 122492064 , 21311 to 122492285 , 21312 strand plus , 21313 id 21314 gi 51860767 } , 21315 { 21316 from 122493968 , 21317 to 122494172 , 21318 strand plus , 21319 id 21320 gi 51860767 } , 21321 { 21322 from 122498257 , 21323 to 122498322 , 21324 strand plus , 21325 id 21326 gi 51860767 } , 21327 { 21328 from 122501632 , 21329 to 122501721 , 21330 strand plus , 21331 id 21332 gi 51860767 } , 21333 { 21334 from 122503233 , 21335 to 122503407 , 21336 strand plus , 21337 id 21338 gi 51860767 } , 21339 { 21340 from 122505161 , 21341 to 122505292 , 21342 strand plus , 21343 id 21344 gi 51860767 } , 21345 { 21346 from 122507723 , 21347 to 122507862 , 21348 strand plus , 21349 id 21350 gi 51860767 } , 21351 { 21352 from 122508424 , 21353 to 122508561 , 21354 strand plus , 21355 id 21356 gi 51860767 } , 21357 { 21358 from 122509727 , 21359 to 122509920 , 21360 strand plus , 21361 id 21362 gi 51860767 } , 21363 { 21364 from 122510918 , 21365 to 122511002 , 21366 strand plus , 21367 id 21368 gi 51860767 } , 21369 { 21370 from 122514126 , 21371 to 122514331 , 21372 strand plus , 21373 id 21374 gi 51860767 } , 21375 { 21376 from 122514655 , 21377 to 122514703 , 21378 strand plus , 21379 id 21380 gi 51860767 } , 21381 { 21382 from 122516604 , 21383 to 122516866 , 21384 strand plus , 21385 id 21386 gi 51860767 } , 21387 { 21388 from 122518583 , 21389 to 122518707 , 21390 strand plus , 21391 id 21392 gi 51860767 } , 21393 { 21394 from 122519172 , 21395 to 122519270 , 21396 strand plus , 21397 id 21398 gi 51860767 } , 21399 { 21400 from 122520026 , 21401 to 122520212 , 21402 strand plus , 21403 id 21404 gi 51860767 } , 21405 { 21406 from 122523293 , 21407 to 122523387 , 21408 strand plus , 21409 id 21410 gi 51860767 } , 21411 { 21412 from 122525002 , 21413 to 122525034 , 21414 strand plus , 21415 id 21416 gi 51860767 } , 21417 { 21418 from 122528800 , 21419 to 122528905 , 21420 strand plus , 21421 id 21422 gi 51860767 } , 21423 { 21424 from 122529033 , 21425 to 122529107 , 21426 strand plus , 21427 id 21428 gi 51860767 } , 21429 { 21430 from 122529332 , 21431 to 122529501 , 21432 strand plus , 21433 id 21434 gi 51860767 } , 21435 { 21436 from 122530477 , 21437 to 122530654 , 21438 strand plus , 21439 id 21440 gi 51860767 } , 21441 { 21442 from 122536879 , 21443 to 122536994 , 21444 strand plus , 21445 id 21446 gi 51860767 } , 21447 { 21448 from 122537940 , 21449 to 122538087 , 21450 strand plus , 21451 id 21452 gi 51860767 } , 21453 { 21454 from 122539437 , 21455 to 122539560 , 21456 strand plus , 21457 id 21458 gi 51860767 } , 21459 { 21460 from 122539916 , 21461 to 122540045 , 21462 strand plus , 21463 id 21464 gi 51860767 } , 21465 { 21466 from 122543903 , 21467 to 122544023 , 21468 strand plus , 21469 id 21470 gi 51860767 } , 21471 { 21472 from 122544463 , 21473 to 122544525 , 21474 strand plus , 21475 id 21476 gi 51860767 } , 21477 { 21478 from 122545390 , 21479 to 122545496 , 21480 strand plus , 21481 id 21482 gi 51860767 } , 21483 { 21484 from 122548250 , 21485 to 122548391 , 21486 strand plus , 21487 id 21488 gi 51860767 } , 21489 { 21490 from 122551495 , 21491 to 122551629 , 21492 strand plus , 21493 id 21494 gi 51860767 } , 21495 { 21496 from 122552344 , 21497 to 122552447 , 21498 strand plus , 21499 id 21500 gi 51860767 } , 21501 { 21502 from 122552531 , 21503 to 122552623 , 21504 strand plus , 21505 id 21506 gi 51860767 } , 21507 { 21508 from 122555381 , 21509 to 122555630 , 21510 strand plus , 21511 id 21512 gi 51860767 } , 21513 { 21514 from 122557676 , 21515 to 122557762 , 21516 strand plus , 21517 id 21518 gi 51860767 } , 21519 { 21520 from 122561316 , 21521 to 122561435 , 21522 strand plus , 21523 id 21524 gi 51860767 } } } , 21525 seqs { 21526 whole 21527 gi 6671495 } } } } } } , 21528 { 21529 type genomic , 21530 heading "Reference" , 21531 accession "NT_039240" , 21532 version 3 , 21533 seqs { 21534 int { 21535 from 8569036 , 21536 to 8704333 , 21537 strand plus , 21538 id 21539 gi 51708444 } } , 21540 products { 21541 { 21542 type mRNA , 21543 heading "Reference" , 21544 accession "NM_007378" , 21545 version 1 , 21546 genomic-coords { 21547 mix { 21548 int { 21549 from 8569036 , 21550 to 8569188 , 21551 strand plus , 21552 id 21553 gi 51708444 } , 21554 int { 21555 from 8577537 , 21556 to 8577630 , 21557 strand plus , 21558 id 21559 gi 51708444 } , 21560 int { 21561 from 8578827 , 21562 to 8578968 , 21563 strand plus , 21564 id 21565 gi 51708444 } , 21566 int { 21567 from 8579953 , 21568 to 8580092 , 21569 strand plus , 21570 id 21571 gi 51708444 } , 21572 int { 21573 from 8587411 , 21574 to 8587538 , 21575 strand plus , 21576 id 21577 gi 51708444 } , 21578 int { 21579 from 8593804 , 21580 to 8594001 , 21581 strand plus , 21582 id 21583 gi 51708444 } , 21584 int { 21585 from 8605174 , 21586 to 8605263 , 21587 strand plus , 21588 id 21589 gi 51708444 } , 21590 int { 21591 from 8608117 , 21592 to 8608357 , 21593 strand plus , 21594 id 21595 gi 51708444 } , 21596 int { 21597 from 8609799 , 21598 to 8609938 , 21599 strand plus , 21600 id 21601 gi 51708444 } , 21602 int { 21603 from 8610824 , 21604 to 8610940 , 21605 strand plus , 21606 id 21607 gi 51708444 } , 21608 int { 21609 from 8611559 , 21610 to 8611756 , 21611 strand plus , 21612 id 21613 gi 51708444 } , 21614 int { 21615 from 8626948 , 21616 to 8627153 , 21617 strand plus , 21618 id 21619 gi 51708444 } , 21620 int { 21621 from 8627707 , 21622 to 8627883 , 21623 strand plus , 21624 id 21625 gi 51708444 } , 21626 int { 21627 from 8629580 , 21628 to 8629802 , 21629 strand plus , 21630 id 21631 gi 51708444 } , 21632 int { 21633 from 8634734 , 21634 to 8634955 , 21635 strand plus , 21636 id 21637 gi 51708444 } , 21638 int { 21639 from 8636638 , 21640 to 8636842 , 21641 strand plus , 21642 id 21643 gi 51708444 } , 21644 int { 21645 from 8640927 , 21646 to 8640992 , 21647 strand plus , 21648 id 21649 gi 51708444 } , 21650 int { 21651 from 8644302 , 21652 to 8644391 , 21653 strand plus , 21654 id 21655 gi 51708444 } , 21656 int { 21657 from 8645903 , 21658 to 8646077 , 21659 strand plus , 21660 id 21661 gi 51708444 } , 21662 int { 21663 from 8647831 , 21664 to 8647962 , 21665 strand plus , 21666 id 21667 gi 51708444 } , 21668 int { 21669 from 8650393 , 21670 to 8650532 , 21671 strand plus , 21672 id 21673 gi 51708444 } , 21674 int { 21675 from 8651094 , 21676 to 8651231 , 21677 strand plus , 21678 id 21679 gi 51708444 } , 21680 int { 21681 from 8652397 , 21682 to 8652590 , 21683 strand plus , 21684 id 21685 gi 51708444 } , 21686 int { 21687 from 8653588 , 21688 to 8653672 , 21689 strand plus , 21690 id 21691 gi 51708444 } , 21692 int { 21693 from 8656796 , 21694 to 8657001 , 21695 strand plus , 21696 id 21697 gi 51708444 } , 21698 int { 21699 from 8657325 , 21700 to 8657373 , 21701 strand plus , 21702 id 21703 gi 51708444 } , 21704 int { 21705 from 8659274 , 21706 to 8659536 , 21707 strand plus , 21708 id 21709 gi 51708444 } , 21710 int { 21711 from 8661253 , 21712 to 8661377 , 21713 strand plus , 21714 id 21715 gi 51708444 } , 21716 int { 21717 from 8661842 , 21718 to 8661940 , 21719 strand plus , 21720 id 21721 gi 51708444 } , 21722 int { 21723 from 8662696 , 21724 to 8662882 , 21725 strand plus , 21726 id 21727 gi 51708444 } , 21728 int { 21729 from 8665963 , 21730 to 8666057 , 21731 strand plus , 21732 id 21733 gi 51708444 } , 21734 int { 21735 from 8667672 , 21736 to 8667704 , 21737 strand plus , 21738 id 21739 gi 51708444 } , 21740 int { 21741 from 8671470 , 21742 to 8671575 , 21743 strand plus , 21744 id 21745 gi 51708444 } , 21746 int { 21747 from 8671703 , 21748 to 8671777 , 21749 strand plus , 21750 id 21751 gi 51708444 } , 21752 int { 21753 from 8672002 , 21754 to 8672171 , 21755 strand plus , 21756 id 21757 gi 51708444 } , 21758 int { 21759 from 8673147 , 21760 to 8673324 , 21761 strand plus , 21762 id 21763 gi 51708444 } , 21764 int { 21765 from 8679549 , 21766 to 8679664 , 21767 strand plus , 21768 id 21769 gi 51708444 } , 21770 int { 21771 from 8680610 , 21772 to 8680757 , 21773 strand plus , 21774 id 21775 gi 51708444 } , 21776 int { 21777 from 8682107 , 21778 to 8682230 , 21779 strand plus , 21780 id 21781 gi 51708444 } , 21782 int { 21783 from 8682586 , 21784 to 8682715 , 21785 strand plus , 21786 id 21787 gi 51708444 } , 21788 int { 21789 from 8686573 , 21790 to 8686693 , 21791 strand plus , 21792 id 21793 gi 51708444 } , 21794 int { 21795 from 8687133 , 21796 to 8687195 , 21797 strand plus , 21798 id 21799 gi 51708444 } , 21800 int { 21801 from 8688060 , 21802 to 8688166 , 21803 strand plus , 21804 id 21805 gi 51708444 } , 21806 int { 21807 from 8690920 , 21808 to 8691061 , 21809 strand plus , 21810 id 21811 gi 51708444 } , 21812 int { 21813 from 8694165 , 21814 to 8694299 , 21815 strand plus , 21816 id 21817 gi 51708444 } , 21818 int { 21819 from 8695014 , 21820 to 8695117 , 21821 strand plus , 21822 id 21823 gi 51708444 } , 21824 int { 21825 from 8695201 , 21826 to 8695293 , 21827 strand plus , 21828 id 21829 gi 51708444 } , 21830 int { 21831 from 8698051 , 21832 to 8698300 , 21833 strand plus , 21834 id 21835 gi 51708444 } , 21836 int { 21837 from 8700346 , 21838 to 8700432 , 21839 strand plus , 21840 id 21841 gi 51708444 } , 21842 int { 21843 from 8703986 , 21844 to 8704333 , 21845 strand plus , 21846 id 21847 gi 51708444 } } } , 21848 seqs { 21849 whole 21850 gi 6671494 } , 21851 products { 21852 { 21853 type peptide , 21854 heading "Reference" , 21855 accession "NP_031404" , 21856 version 1 , 21857 genomic-coords { 21858 packed-int { 21859 { 21860 from 8569123 , 21861 to 8569188 , 21862 strand plus , 21863 id 21864 gi 51708444 } , 21865 { 21866 from 8577537 , 21867 to 8577630 , 21868 strand plus , 21869 id 21870 gi 51708444 } , 21871 { 21872 from 8578827 , 21873 to 8578968 , 21874 strand plus , 21875 id 21876 gi 51708444 } , 21877 { 21878 from 8579953 , 21879 to 8580092 , 21880 strand plus , 21881 id 21882 gi 51708444 } , 21883 { 21884 from 8587411 , 21885 to 8587538 , 21886 strand plus , 21887 id 21888 gi 51708444 } , 21889 { 21890 from 8593804 , 21891 to 8594001 , 21892 strand plus , 21893 id 21894 gi 51708444 } , 21895 { 21896 from 8605174 , 21897 to 8605263 , 21898 strand plus , 21899 id 21900 gi 51708444 } , 21901 { 21902 from 8608117 , 21903 to 8608357 , 21904 strand plus , 21905 id 21906 gi 51708444 } , 21907 { 21908 from 8609799 , 21909 to 8609938 , 21910 strand plus , 21911 id 21912 gi 51708444 } , 21913 { 21914 from 8610824 , 21915 to 8610940 , 21916 strand plus , 21917 id 21918 gi 51708444 } , 21919 { 21920 from 8611559 , 21921 to 8611756 , 21922 strand plus , 21923 id 21924 gi 51708444 } , 21925 { 21926 from 8626948 , 21927 to 8627153 , 21928 strand plus , 21929 id 21930 gi 51708444 } , 21931 { 21932 from 8627707 , 21933 to 8627883 , 21934 strand plus , 21935 id 21936 gi 51708444 } , 21937 { 21938 from 8629580 , 21939 to 8629802 , 21940 strand plus , 21941 id 21942 gi 51708444 } , 21943 { 21944 from 8634734 , 21945 to 8634955 , 21946 strand plus , 21947 id 21948 gi 51708444 } , 21949 { 21950 from 8636638 , 21951 to 8636842 , 21952 strand plus , 21953 id 21954 gi 51708444 } , 21955 { 21956 from 8640927 , 21957 to 8640992 , 21958 strand plus , 21959 id 21960 gi 51708444 } , 21961 { 21962 from 8644302 , 21963 to 8644391 , 21964 strand plus , 21965 id 21966 gi 51708444 } , 21967 { 21968 from 8645903 , 21969 to 8646077 , 21970 strand plus , 21971 id 21972 gi 51708444 } , 21973 { 21974 from 8647831 , 21975 to 8647962 , 21976 strand plus , 21977 id 21978 gi 51708444 } , 21979 { 21980 from 8650393 , 21981 to 8650532 , 21982 strand plus , 21983 id 21984 gi 51708444 } , 21985 { 21986 from 8651094 , 21987 to 8651231 , 21988 strand plus , 21989 id 21990 gi 51708444 } , 21991 { 21992 from 8652397 , 21993 to 8652590 , 21994 strand plus , 21995 id 21996 gi 51708444 } , 21997 { 21998 from 8653588 , 21999 to 8653672 , 22000 strand plus , 22001 id 22002 gi 51708444 } , 22003 { 22004 from 8656796 , 22005 to 8657001 , 22006 strand plus , 22007 id 22008 gi 51708444 } , 22009 { 22010 from 8657325 , 22011 to 8657373 , 22012 strand plus , 22013 id 22014 gi 51708444 } , 22015 { 22016 from 8659274 , 22017 to 8659536 , 22018 strand plus , 22019 id 22020 gi 51708444 } , 22021 { 22022 from 8661253 , 22023 to 8661377 , 22024 strand plus , 22025 id 22026 gi 51708444 } , 22027 { 22028 from 8661842 , 22029 to 8661940 , 22030 strand plus , 22031 id 22032 gi 51708444 } , 22033 { 22034 from 8662696 , 22035 to 8662882 , 22036 strand plus , 22037 id 22038 gi 51708444 } , 22039 { 22040 from 8665963 , 22041 to 8666057 , 22042 strand plus , 22043 id 22044 gi 51708444 } , 22045 { 22046 from 8667672 , 22047 to 8667704 , 22048 strand plus , 22049 id 22050 gi 51708444 } , 22051 { 22052 from 8671470 , 22053 to 8671575 , 22054 strand plus , 22055 id 22056 gi 51708444 } , 22057 { 22058 from 8671703 , 22059 to 8671777 , 22060 strand plus , 22061 id 22062 gi 51708444 } , 22063 { 22064 from 8672002 , 22065 to 8672171 , 22066 strand plus , 22067 id 22068 gi 51708444 } , 22069 { 22070 from 8673147 , 22071 to 8673324 , 22072 strand plus , 22073 id 22074 gi 51708444 } , 22075 { 22076 from 8679549 , 22077 to 8679664 , 22078 strand plus , 22079 id 22080 gi 51708444 } , 22081 { 22082 from 8680610 , 22083 to 8680757 , 22084 strand plus , 22085 id 22086 gi 51708444 } , 22087 { 22088 from 8682107 , 22089 to 8682230 , 22090 strand plus , 22091 id 22092 gi 51708444 } , 22093 { 22094 from 8682586 , 22095 to 8682715 , 22096 strand plus , 22097 id 22098 gi 51708444 } , 22099 { 22100 from 8686573 , 22101 to 8686693 , 22102 strand plus , 22103 id 22104 gi 51708444 } , 22105 { 22106 from 8687133 , 22107 to 8687195 , 22108 strand plus , 22109 id 22110 gi 51708444 } , 22111 { 22112 from 8688060 , 22113 to 8688166 , 22114 strand plus , 22115 id 22116 gi 51708444 } , 22117 { 22118 from 8690920 , 22119 to 8691061 , 22120 strand plus , 22121 id 22122 gi 51708444 } , 22123 { 22124 from 8694165 , 22125 to 8694299 , 22126 strand plus , 22127 id 22128 gi 51708444 } , 22129 { 22130 from 8695014 , 22131 to 8695117 , 22132 strand plus , 22133 id 22134 gi 51708444 } , 22135 { 22136 from 8695201 , 22137 to 8695293 , 22138 strand plus , 22139 id 22140 gi 51708444 } , 22141 { 22142 from 8698051 , 22143 to 8698300 , 22144 strand plus , 22145 id 22146 gi 51708444 } , 22147 { 22148 from 8700346 , 22149 to 8700432 , 22150 strand plus , 22151 id 22152 gi 51708444 } , 22153 { 22154 from 8703986 , 22155 to 8704105 , 22156 strand plus , 22157 id 22158 gi 51708444 } } } , 22159 seqs { 22160 whole 22161 gi 6671495 } } } } } } } , 22162 properties { 22163 { 22164 type comment , 22165 label "Nomenclature" , 22166 version 0 , 22167 source { 22168 { 22169 anchor "Mouse Genome Informatics" } } , 22170 properties { 22171 { 22172 type property , 22173 label "Official Symbol" , 22174 text "Abca4" , 22175 version 0 } , 22176 { 22177 type property , 22178 label "Official Full Name" , 22179 text "ATP-binding cassette, sub-family A (ABC1), member 4" , 22180 version 0 } } } , 22181 { 22182 type comment , 22183 heading "GeneOntology" , 22184 version 0 , 22185 source { 22186 { 22187 pre-text "Provided by" , 22188 anchor "MGI" , 22189 url "http://www.informatics.jax.org/" } } , 22190 comment { 22191 { 22192 type comment , 22193 label "Function" , 22194 version 0 , 22195 comment { 22196 { 22197 type comment , 22198 version 0 , 22199 source { 22200 { 22201 src { 22202 db "GO" , 22203 tag 22204 id 5524 } , 22205 anchor "ATP binding" , 22206 post-text "evidence: IEA" } } } , 22207 { 22208 type comment , 22209 version 0 , 22210 source { 22211 { 22212 src { 22213 db "GO" , 22214 tag 22215 id 16887 } , 22216 anchor "ATPase activity" , 22217 post-text "evidence: IEA" } } } , 22218 { 22219 type comment , 22220 version 0 , 22221 refs { 22222 pmid 9202155 } , 22223 source { 22224 { 22225 src { 22226 db "GO" , 22227 tag 22228 id 42626 } , 22229 anchor "ATPase activity, coupled to transmembrane movement 22230 of substances" , 22231 post-text "evidence: TAS" } } } , 22232 { 22233 type comment , 22234 version 0 , 22235 refs { 22236 pmid 10412977 } , 22237 source { 22238 { 22239 src { 22240 db "GO" , 22241 tag 22242 id 5548 } , 22243 anchor "phospholipid transporter activity" , 22244 post-text "evidence: IMP" } } } , 22245 { 22246 type comment , 22247 version 0 , 22248 refs { 22249 pmid 10412977 } , 22250 source { 22251 { 22252 src { 22253 db "GO" , 22254 tag 22255 id 4012 } , 22256 anchor "phospholipid-translocating ATPase activity" , 22257 post-text "evidence: IMP" } } } } } , 22258 { 22259 type comment , 22260 label "Process" , 22261 version 0 , 22262 comment { 22263 { 22264 type comment , 22265 version 0 , 22266 refs { 22267 pmid 10412977 } , 22268 source { 22269 { 22270 src { 22271 db "GO" , 22272 tag 22273 id 6649 } , 22274 anchor "phospholipid transfer to membrane" , 22275 post-text "evidence: IMP" } } } , 22276 { 22277 type comment , 22278 version 0 , 22279 refs { 22280 pmid 11431429 } , 22281 source { 22282 { 22283 src { 22284 db "GO" , 22285 tag 22286 id 45494 } , 22287 anchor "photoreceptor maintenance" , 22288 post-text "evidence: IMP" } } } , 22289 { 22290 type comment , 22291 version 0 , 22292 source { 22293 { 22294 src { 22295 db "GO" , 22296 tag 22297 id 7600 } , 22298 anchor "sensory perception" , 22299 post-text "evidence: IEA" } } } , 22300 { 22301 type comment , 22302 version 0 , 22303 source { 22304 { 22305 src { 22306 db "GO" , 22307 tag 22308 id 6810 } , 22309 anchor "transport" , 22310 post-text "evidence: IEA" } } } , 22311 { 22312 type comment , 22313 version 0 , 22314 refs { 22315 pmid 10412977 } , 22316 source { 22317 { 22318 src { 22319 db "GO" , 22320 tag 22321 id 7601 } , 22322 anchor "visual perception" , 22323 post-text "evidence: IMP" } } } } } , 22324 { 22325 type comment , 22326 label "Component" , 22327 version 0 , 22328 comment { 22329 { 22330 type comment , 22331 version 0 , 22332 source { 22333 { 22334 src { 22335 db "GO" , 22336 tag 22337 id 16021 } , 22338 anchor "integral to membrane" , 22339 post-text "evidence: IEA" } } } , 22340 { 22341 type comment , 22342 version 0 , 22343 refs { 22344 pmid 9202155 } , 22345 source { 22346 { 22347 src { 22348 db "GO" , 22349 tag 22350 id 5887 } , 22351 anchor "integral to plasma membrane" , 22352 post-text "evidence: TAS" } } } } } } } } , 22353 homology { 22354 { 22355 type comment , 22356 heading "Human, Rat" , 22357 version 0 , 22358 source { 22359 { 22360 src { 22361 db "HomoloGene" , 22362 tag 22363 id 298 } , 22364 anchor "Map Viewer" , 22365 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=3& 22366MAPS=genes-r-org/human-chr/mouse%3A3,genes-r-org/rat-chr/mouse%3A3,genes-r-org 22367/mouse-chr3&query=e%3A11304[id]+AND+gene[obj_type]&QSTR=abca4&cmd=focus&fill=1 223680" } } } } , 22369 comments { 22370 { 22371 type comment , 22372 heading "LocusTagLink" , 22373 version 0 , 22374 source { 22375 { 22376 src { 22377 db "MGI" , 22378 tag 22379 id 109424 } } } } , 22380 { 22381 type comment , 22382 heading "RefSeq Status" , 22383 label "REVIEWED" , 22384 version 0 } , 22385 { 22386 type comment , 22387 version 0 , 22388 refs { 22389 pmid 12477932 , 22390 pmid 12466851 , 22391 pmid 11431429 , 22392 pmid 11217851 , 22393 pmid 11076861 , 22394 pmid 11042159 , 22395 pmid 10852960 , 22396 pmid 10412977 , 22397 pmid 10349636 , 22398 pmid 9202155 , 22399 pmid 8889548 } } , 22400 { 22401 type comment , 22402 heading "Markers (Sequence Tagged Sites/STS)" , 22403 version 0 , 22404 comment { 22405 { 22406 type comment , 22407 version 0 , 22408 source { 22409 { 22410 src { 22411 db "UniSTS" , 22412 tag 22413 id 140994 } , 22414 anchor "Abca4" , 22415 post-text "(e-PCR)" } } , 22416 comment { 22417 { 22418 type other , 22419 label "Alternate name" , 22420 text "MGI:8523" , 22421 version 0 } } } , 22422 { 22423 type comment , 22424 version 0 , 22425 source { 22426 { 22427 src { 22428 db "UniSTS" , 22429 tag 22430 id 159184 } , 22431 anchor "AF000149" , 22432 post-text "(e-PCR)" } } , 22433 comment { 22434 { 22435 type other , 22436 label "Alternate name" , 22437 text "192133" , 22438 version 0 } , 22439 { 22440 type other , 22441 label "Alternate name" , 22442 text "693384" , 22443 version 0 } , 22444 { 22445 type other , 22446 label "Alternate name" , 22447 text "ND" , 22448 version 0 } } } } } , 22449 { 22450 type comment , 22451 heading "NCBI Reference Sequences (RefSeq)" , 22452 version 0 , 22453 products { 22454 { 22455 type mRNA , 22456 heading "mRNA Sequence" , 22457 accession "NM_007378" , 22458 version 1 , 22459 source { 22460 { 22461 src { 22462 db "Nucleotide" , 22463 tag 22464 id 6671494 } , 22465 anchor "NM_007378" } } , 22466 seqs { 22467 whole 22468 gi 6671494 } , 22469 products { 22470 { 22471 type peptide , 22472 heading "Product" , 22473 accession "NP_031404" , 22474 version 1 , 22475 source { 22476 { 22477 src { 22478 db "Protein" , 22479 tag 22480 id 6671495 } , 22481 anchor "NP_031404" , 22482 post-text "ATP-binding cassette, sub-family A, member 4" } } , 22483 seqs { 22484 whole 22485 gi 6671495 } , 22486 comment { 22487 { 22488 type other , 22489 heading "Conserved Domains" , 22490 version 0 , 22491 source { 22492 { 22493 src { 22494 db "PROT_CDD" , 22495 tag 22496 id 6671495 } , 22497 pre-text "(3)" , 22498 anchor "summary" } } , 22499 comment { 22500 { 22501 type other , 22502 version 0 , 22503 source { 22504 { 22505 src { 22506 db "CDD" , 22507 tag 22508 id 5341 } , 22509 anchor "cd00267: ABC_ATPase; ABC (ATP-binding 22510 cassette) transporter nucleotide-binding domain" } } , 22511 comment { 22512 { 22513 type other , 22514 text "Location: 931 - 1144 Blast Score: 454" , 22515 version 0 } , 22516 { 22517 type other , 22518 text "Location: 1937 - 2152 Blast Score: 353" , 22519 version 0 } } } , 22520 { 22521 type other , 22522 version 0 , 22523 source { 22524 { 22525 src { 22526 db "CDD" , 22527 tag 22528 id 13428 } , 22529 anchor "COG4152: COG4152; ABC-type uncharacterized 22530 transport system, ATPase component [General function prediction only]" } } , 22531 comment { 22532 { 22533 type other , 22534 text "Location: 1937 - 2253 Blast Score: 387" , 22535 version 0 } } } } } } } } , 22536 comment { 22537 { 22538 type other , 22539 heading "Source Sequence" , 22540 version 0 , 22541 source { 22542 { 22543 src { 22544 db "Nucleotide" , 22545 tag 22546 str "AF000149" } , 22547 anchor "AF000149" } } , 22548 comment { 22549 { 22550 type other , 22551 version 0 } } } } } } } , 22552 { 22553 type comment , 22554 heading "Related Sequences" , 22555 version 0 , 22556 products { 22557 { 22558 type mRNA , 22559 heading "mRNA" , 22560 accession "AF000149" , 22561 version 1 , 22562 source { 22563 { 22564 src { 22565 db "Nucleotide" , 22566 tag 22567 id 3243083 } , 22568 anchor "AF000149" } } , 22569 seqs { 22570 whole 22571 gi 3243083 } , 22572 products { 22573 { 22574 type peptide , 22575 accession "AAC23916" , 22576 version 1 , 22577 source { 22578 { 22579 src { 22580 db "Protein" , 22581 tag 22582 id 2547314 } , 22583 anchor "AAC23916" } } , 22584 seqs { 22585 whole 22586 gi 2547314 } } } , 22587 comment { 22588 { 22589 type other , 22590 label "Strain" , 22591 text "C57BL/6" , 22592 version 0 } } } , 22593 { 22594 type mRNA , 22595 heading "mRNA" , 22596 accession "AK053043" , 22597 version 1 , 22598 source { 22599 { 22600 src { 22601 db "Nucleotide" , 22602 tag 22603 id 26095532 } , 22604 anchor "AK053043" } } , 22605 seqs { 22606 whole 22607 gi 26095532 } , 22608 products { 22609 { 22610 type peptide , 22611 text "None" , 22612 version 0 } } , 22613 comment { 22614 { 22615 type other , 22616 label "Strain" , 22617 text "C57BL/6J" , 22618 version 0 } } } , 22619 { 22620 type mRNA , 22621 heading "mRNA" , 22622 accession "AK084860" , 22623 version 1 , 22624 source { 22625 { 22626 src { 22627 db "Nucleotide" , 22628 tag 22629 id 26102289 } , 22630 anchor "AK084860" } } , 22631 seqs { 22632 whole 22633 gi 26102289 } , 22634 products { 22635 { 22636 type peptide , 22637 text "None" , 22638 version 0 } } , 22639 comment { 22640 { 22641 type other , 22642 label "Strain" , 22643 text "C57BL/6J" , 22644 version 0 } } } , 22645 { 22646 type mRNA , 22647 heading "mRNA" , 22648 accession "BC043937" , 22649 version 1 , 22650 source { 22651 { 22652 src { 22653 db "Nucleotide" , 22654 tag 22655 id 27882179 } , 22656 anchor "BC043937" } } , 22657 seqs { 22658 whole 22659 gi 27882179 } , 22660 products { 22661 { 22662 type peptide , 22663 accession "AAH43937" , 22664 version 1 , 22665 source { 22666 { 22667 src { 22668 db "Protein" , 22669 tag 22670 id 27882180 } , 22671 anchor "AAH43937" } } , 22672 seqs { 22673 whole 22674 gi 27882180 } } } } , 22675 { 22676 type mRNA , 22677 heading "mRNA" , 22678 accession "BC057853" , 22679 version 1 , 22680 source { 22681 { 22682 src { 22683 db "Nucleotide" , 22684 tag 22685 id 34783941 } , 22686 anchor "BC057853" } } , 22687 seqs { 22688 whole 22689 gi 34783941 } , 22690 products { 22691 { 22692 type peptide , 22693 accession "AAH57853" , 22694 version 1 , 22695 source { 22696 { 22697 src { 22698 db "Protein" , 22699 tag 22700 id 34783942 } , 22701 anchor "AAH57853" } } , 22702 seqs { 22703 whole 22704 gi 34783942 } } } } } } , 22705 { 22706 type comment , 22707 heading "Additional Links" , 22708 version 0 , 22709 comment { 22710 { 22711 type comment , 22712 version 0 , 22713 source { 22714 { 22715 src { 22716 db "Evidence Viewer" , 22717 tag 22718 str "11304" } , 22719 anchor "Evidence Viewer" , 22720 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont 22721ig=NT_039240.3&gene=Abca4&lid=11304&from=8569037&to=8704334" } } } , 22722 { 22723 type comment , 22724 version 0 , 22725 source { 22726 { 22727 src { 22728 db "ModelMaker" , 22729 tag 22730 str "11304" } , 22731 anchor "ModelMaker" , 22732 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10 22733090&contig=NT_039240.3&gene=Abca4&lid=11304" } } } , 22734 { 22735 type comment , 22736 text "UniGene" , 22737 version 0 , 22738 xtra-properties { 22739 { 22740 tag "UNIGENE" , 22741 value "Mm.3918" } } , 22742 source { 22743 { 22744 src { 22745 db "UniGene" , 22746 tag 22747 str "Mm.3918" } , 22748 anchor "Mm.3918" , 22749 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=39 2275018" } } } , 22751 { 22752 type comment , 22753 version 0 , 22754 source { 22755 { 22756 src { 22757 db "HomoloGene" , 22758 tag 22759 str "11304" } , 22760 anchor "HomoloGene" , 22761 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 2276211304[loc]&TAXID=10090" } } } , 22763 { 22764 type comment , 22765 version 0 , 22766 source { 22767 { 22768 src { 22769 db "MGI" , 22770 tag 22771 id 109424 } , 22772 anchor "MGI" , 22773 url "http://www.informatics.jax.org/searches/accession_report.cg 22774i?id=MGI:109424" } } } , 22775 { 22776 type comment , 22777 version 0 , 22778 source { 22779 { 22780 src { 22781 db "Ensembl" , 22782 tag 22783 str "" } , 22784 url "http://www.ensembl.org/Mus_musculus/contigview?geneid=BC057 22785853" } } } , 22786 { 22787 type comment , 22788 version 0 , 22789 source { 22790 { 22791 src { 22792 db "UCSC" , 22793 tag 22794 str "" } , 22795 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position= 22796BC057853" } } } , 22797 { 22798 type comment , 22799 text "Human ABC-Transporter Proteins" , 22800 version 0 , 22801 source { 22802 { 22803 src { 22804 db "Human ABC-Transporter Proteins" , 22805 tag 22806 str "Human ABC-Transporter Proteins" } , 22807 anchor "Human ABC-Transporter Proteins" , 22808 url "http://nutrigene.4t.com/humanabc.htm" } } } } } , 22809 { 22810 type comment , 22811 heading "Alleles" , 22812 version 0 , 22813 comment { 22814 { 22815 type comment , 22816 text "The following allele types are documented at Mouse Genome 22817 Informatics" , 22818 version 0 , 22819 source { 22820 { 22821 anchor "(MGI)" , 22822 url "http://www.informatics.jax.org/searches/allele_report.cgi?m 22823arkerID=MGI:109424" } } } , 22824 { 22825 type comment , 22826 heading "Targeted (knock-out) (1)" , 22827 version 0 , 22828 refs { 22829 pmid 10412977 } } } } } , 22830 unique-keys { 22831 { 22832 db "LocusID" , 22833 tag 22834 id 11304 } , 22835 { 22836 db "MGI" , 22837 tag 22838 id 109424 } } , 22839 xtra-index-terms { 22840 "LOC11304" } } 22841Entrezgene ::= { 22842 track-info { 22843 geneid 11305 , 22844 status live , 22845 create-date 22846 std { 22847 year 2003 , 22848 month 8 , 22849 day 28 , 22850 hour 21 , 22851 minute 39 , 22852 second 0 } , 22853 update-date 22854 std { 22855 year 2005 , 22856 month 2 , 22857 day 17 , 22858 hour 12 , 22859 minute 54 , 22860 second 0 } } , 22861 type protein-coding , 22862 source { 22863 genome genomic , 22864 origin natural , 22865 org { 22866 taxname "Mus musculus" , 22867 common "house mouse" , 22868 db { 22869 { 22870 db "taxon" , 22871 tag 22872 id 10090 } } , 22873 syn { 22874 "mouse" } , 22875 orgname { 22876 name 22877 binomial { 22878 genus "Mus" , 22879 species "musculus" } , 22880 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 22881 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 22882 Sciurognathi; Muridae; Murinae; Mus" , 22883 gcode 1 , 22884 mgcode 2 , 22885 div "ROD" } } , 22886 subtype { 22887 { 22888 subtype chromosome , 22889 name "2" } } } , 22890 gene { 22891 locus "Abca2" , 22892 desc "ATP-binding cassette, sub-family A (ABC1), member 2" , 22893 maploc "2 12.6 cM" , 22894 syn { 22895 "Abc2" , 22896 "mKIAA1062" , 22897 "D2H0S1474E" } , 22898 locus-tag "MGI:99606" } , 22899 prot { 22900 name { 22901 "ATP-binding cassette, sub-family A (ABC1), member 2" , 22902 "ATP-binding cassette 2" } } , 22903 location { 22904 { 22905 display-str "2 A2-B" , 22906 method 22907 map-type cyto } , 22908 { 22909 display-str "2 12.6 cM" , 22910 method 22911 map-type cM } } , 22912 gene-source { 22913 src "LocusLink" , 22914 src-int 11305 , 22915 src-str2 "11305" , 22916 gene-display FALSE , 22917 locus-display FALSE , 22918 extra-terms FALSE } , 22919 locus { 22920 { 22921 type genomic , 22922 heading "Reference" , 22923 accession "NC_000068" , 22924 version 1 , 22925 seqs { 22926 int { 22927 from 25388791 , 22928 to 25408220 , 22929 strand plus , 22930 id 22931 gi 51860766 } } , 22932 products { 22933 { 22934 type mRNA , 22935 heading "Reference" , 22936 accession "NM_007379" , 22937 version 1 , 22938 genomic-coords { 22939 mix { 22940 int { 22941 from 25388791 , 22942 to 25388856 , 22943 strand plus , 22944 id 22945 gi 51860766 } , 22946 int { 22947 from 25392017 , 22948 to 25392110 , 22949 strand plus , 22950 id 22951 gi 51860766 } , 22952 int { 22953 from 25393119 , 22954 to 25393230 , 22955 strand plus , 22956 id 22957 gi 51860766 } , 22958 int { 22959 from 25393315 , 22960 to 25393478 , 22961 strand plus , 22962 id 22963 gi 51860766 } , 22964 int { 22965 from 25393703 , 22966 to 25393830 , 22967 strand plus , 22968 id 22969 gi 51860766 } , 22970 int { 22971 from 25393985 , 22972 to 25394095 , 22973 strand plus , 22974 id 22975 gi 51860766 } , 22976 int { 22977 from 25394330 , 22978 to 25394548 , 22979 strand plus , 22980 id 22981 gi 51860766 } , 22982 int { 22983 from 25394911 , 22984 to 25395278 , 22985 strand plus , 22986 id 22987 gi 51860766 } , 22988 int { 22989 from 25395520 , 22990 to 25395679 , 22991 strand plus , 22992 id 22993 gi 51860766 } , 22994 int { 22995 from 25396389 , 22996 to 25396517 , 22997 strand plus , 22998 id 22999 gi 51860766 } , 23000 int { 23001 from 25396610 , 23002 to 25396774 , 23003 strand plus , 23004 id 23005 gi 51860766 } , 23006 int { 23007 from 25396851 , 23008 to 25396947 , 23009 strand plus , 23010 id 23011 gi 51860766 } , 23012 int { 23013 from 25397266 , 23014 to 25397439 , 23015 strand plus , 23016 id 23017 gi 51860766 } , 23018 int { 23019 from 25397509 , 23020 to 25397611 , 23021 strand plus , 23022 id 23023 gi 51860766 } , 23024 int { 23025 from 25397686 , 23026 to 25397800 , 23027 strand plus , 23028 id 23029 gi 51860766 } , 23030 int { 23031 from 25397914 , 23032 to 25398104 , 23033 strand plus , 23034 id 23035 gi 51860766 } , 23036 int { 23037 from 25398252 , 23038 to 25398402 , 23039 strand plus , 23040 id 23041 gi 51860766 } , 23042 int { 23043 from 25398479 , 23044 to 25398683 , 23045 strand plus , 23046 id 23047 gi 51860766 } , 23048 int { 23049 from 25398822 , 23050 to 25398986 , 23051 strand plus , 23052 id 23053 gi 51860766 } , 23054 int { 23055 from 25399088 , 23056 to 25399268 , 23057 strand plus , 23058 id 23059 gi 51860766 } , 23060 int { 23061 from 25399348 , 23062 to 25399560 , 23063 strand plus , 23064 id 23065 gi 51860766 } , 23066 int { 23067 from 25400546 , 23068 to 25400742 , 23069 strand plus , 23070 id 23071 gi 51860766 } , 23072 int { 23073 from 25400831 , 23074 to 25401013 , 23075 strand plus , 23076 id 23077 gi 51860766 } , 23078 int { 23079 from 25401209 , 23080 to 25401393 , 23081 strand plus , 23082 id 23083 gi 51860766 } , 23084 int { 23085 from 25401500 , 23086 to 25401620 , 23087 strand plus , 23088 id 23089 gi 51860766 } , 23090 int { 23091 from 25401896 , 23092 to 25402132 , 23093 strand plus , 23094 id 23095 gi 51860766 } , 23096 int { 23097 from 25402212 , 23098 to 25402418 , 23099 strand plus , 23100 id 23101 gi 51860766 } , 23102 int { 23103 from 25402671 , 23104 to 25402773 , 23105 strand plus , 23106 id 23107 gi 51860766 } , 23108 int { 23109 from 25402856 , 23110 to 25403175 , 23111 strand plus , 23112 id 23113 gi 51860766 } , 23114 int { 23115 from 25403250 , 23116 to 25403463 , 23117 strand plus , 23118 id 23119 gi 51860766 } , 23120 int { 23121 from 25403550 , 23122 to 25403655 , 23123 strand plus , 23124 id 23125 gi 51860766 } , 23126 int { 23127 from 25403747 , 23128 to 25403858 , 23129 strand plus , 23130 id 23131 gi 51860766 } , 23132 int { 23133 from 25403948 , 23134 to 25404008 , 23135 strand plus , 23136 id 23137 gi 51860766 } , 23138 int { 23139 from 25404091 , 23140 to 25404265 , 23141 strand plus , 23142 id 23143 gi 51860766 } , 23144 int { 23145 from 25404346 , 23146 to 25404461 , 23147 strand plus , 23148 id 23149 gi 51860766 } , 23150 int { 23151 from 25404543 , 23152 to 25404690 , 23153 strand plus , 23154 id 23155 gi 51860766 } , 23156 int { 23157 from 25404835 , 23158 to 25404958 , 23159 strand plus , 23160 id 23161 gi 51860766 } , 23162 int { 23163 from 25405093 , 23164 to 25405225 , 23165 strand plus , 23166 id 23167 gi 51860766 } , 23168 int { 23169 from 25405329 , 23170 to 25405446 , 23171 strand plus , 23172 id 23173 gi 51860766 } , 23174 int { 23175 from 25405571 , 23176 to 25405749 , 23177 strand plus , 23178 id 23179 gi 51860766 } , 23180 int { 23181 from 25405991 , 23182 to 25406132 , 23183 strand plus , 23184 id 23185 gi 51860766 } , 23186 int { 23187 from 25406232 , 23188 to 25406366 , 23189 strand plus , 23190 id 23191 gi 51860766 } , 23192 int { 23193 from 25406459 , 23194 to 25406562 , 23195 strand plus , 23196 id 23197 gi 51860766 } , 23198 int { 23199 from 25406636 , 23200 to 25406728 , 23201 strand plus , 23202 id 23203 gi 51860766 } , 23204 int { 23205 from 25406812 , 23206 to 25406914 , 23207 strand plus , 23208 id 23209 gi 51860766 } , 23210 int { 23211 from 25406999 , 23212 to 25407136 , 23213 strand plus , 23214 id 23215 gi 51860766 } , 23216 int { 23217 from 25407221 , 23218 to 25407421 , 23219 strand plus , 23220 id 23221 gi 51860766 } , 23222 int { 23223 from 25407862 , 23224 to 25408220 , 23225 strand plus , 23226 id 23227 gi 51860766 } } } , 23228 seqs { 23229 whole 23230 gi 11993938 } , 23231 products { 23232 { 23233 type peptide , 23234 heading "Reference" , 23235 accession "NP_031405" , 23236 version 1 , 23237 genomic-coords { 23238 packed-int { 23239 { 23240 from 25388791 , 23241 to 25388856 , 23242 strand plus , 23243 id 23244 gi 51860766 } , 23245 { 23246 from 25392017 , 23247 to 25392110 , 23248 strand plus , 23249 id 23250 gi 51860766 } , 23251 { 23252 from 25393119 , 23253 to 25393230 , 23254 strand plus , 23255 id 23256 gi 51860766 } , 23257 { 23258 from 25393315 , 23259 to 25393478 , 23260 strand plus , 23261 id 23262 gi 51860766 } , 23263 { 23264 from 25393703 , 23265 to 25393830 , 23266 strand plus , 23267 id 23268 gi 51860766 } , 23269 { 23270 from 25393985 , 23271 to 25394095 , 23272 strand plus , 23273 id 23274 gi 51860766 } , 23275 { 23276 from 25394330 , 23277 to 25394548 , 23278 strand plus , 23279 id 23280 gi 51860766 } , 23281 { 23282 from 25394911 , 23283 to 25395278 , 23284 strand plus , 23285 id 23286 gi 51860766 } , 23287 { 23288 from 25395520 , 23289 to 25395679 , 23290 strand plus , 23291 id 23292 gi 51860766 } , 23293 { 23294 from 25396389 , 23295 to 25396517 , 23296 strand plus , 23297 id 23298 gi 51860766 } , 23299 { 23300 from 25396610 , 23301 to 25396774 , 23302 strand plus , 23303 id 23304 gi 51860766 } , 23305 { 23306 from 25396851 , 23307 to 25396947 , 23308 strand plus , 23309 id 23310 gi 51860766 } , 23311 { 23312 from 25397266 , 23313 to 25397439 , 23314 strand plus , 23315 id 23316 gi 51860766 } , 23317 { 23318 from 25397509 , 23319 to 25397611 , 23320 strand plus , 23321 id 23322 gi 51860766 } , 23323 { 23324 from 25397686 , 23325 to 25397800 , 23326 strand plus , 23327 id 23328 gi 51860766 } , 23329 { 23330 from 25397914 , 23331 to 25398104 , 23332 strand plus , 23333 id 23334 gi 51860766 } , 23335 { 23336 from 25398252 , 23337 to 25398402 , 23338 strand plus , 23339 id 23340 gi 51860766 } , 23341 { 23342 from 25398479 , 23343 to 25398683 , 23344 strand plus , 23345 id 23346 gi 51860766 } , 23347 { 23348 from 25398822 , 23349 to 25398986 , 23350 strand plus , 23351 id 23352 gi 51860766 } , 23353 { 23354 from 25399088 , 23355 to 25399268 , 23356 strand plus , 23357 id 23358 gi 51860766 } , 23359 { 23360 from 25399348 , 23361 to 25399560 , 23362 strand plus , 23363 id 23364 gi 51860766 } , 23365 { 23366 from 25400546 , 23367 to 25400742 , 23368 strand plus , 23369 id 23370 gi 51860766 } , 23371 { 23372 from 25400831 , 23373 to 25401013 , 23374 strand plus , 23375 id 23376 gi 51860766 } , 23377 { 23378 from 25401209 , 23379 to 25401393 , 23380 strand plus , 23381 id 23382 gi 51860766 } , 23383 { 23384 from 25401500 , 23385 to 25401620 , 23386 strand plus , 23387 id 23388 gi 51860766 } , 23389 { 23390 from 25401896 , 23391 to 25402132 , 23392 strand plus , 23393 id 23394 gi 51860766 } , 23395 { 23396 from 25402212 , 23397 to 25402418 , 23398 strand plus , 23399 id 23400 gi 51860766 } , 23401 { 23402 from 25402671 , 23403 to 25402773 , 23404 strand plus , 23405 id 23406 gi 51860766 } , 23407 { 23408 from 25402856 , 23409 to 25403175 , 23410 strand plus , 23411 id 23412 gi 51860766 } , 23413 { 23414 from 25403250 , 23415 to 25403463 , 23416 strand plus , 23417 id 23418 gi 51860766 } , 23419 { 23420 from 25403550 , 23421 to 25403655 , 23422 strand plus , 23423 id 23424 gi 51860766 } , 23425 { 23426 from 25403747 , 23427 to 25403858 , 23428 strand plus , 23429 id 23430 gi 51860766 } , 23431 { 23432 from 25403948 , 23433 to 25404008 , 23434 strand plus , 23435 id 23436 gi 51860766 } , 23437 { 23438 from 25404091 , 23439 to 25404265 , 23440 strand plus , 23441 id 23442 gi 51860766 } , 23443 { 23444 from 25404346 , 23445 to 25404461 , 23446 strand plus , 23447 id 23448 gi 51860766 } , 23449 { 23450 from 25404543 , 23451 to 25404690 , 23452 strand plus , 23453 id 23454 gi 51860766 } , 23455 { 23456 from 25404835 , 23457 to 25404958 , 23458 strand plus , 23459 id 23460 gi 51860766 } , 23461 { 23462 from 25405093 , 23463 to 25405225 , 23464 strand plus , 23465 id 23466 gi 51860766 } , 23467 { 23468 from 25405329 , 23469 to 25405446 , 23470 strand plus , 23471 id 23472 gi 51860766 } , 23473 { 23474 from 25405571 , 23475 to 25405749 , 23476 strand plus , 23477 id 23478 gi 51860766 } , 23479 { 23480 from 25405991 , 23481 to 25406132 , 23482 strand plus , 23483 id 23484 gi 51860766 } , 23485 { 23486 from 25406232 , 23487 to 25406366 , 23488 strand plus , 23489 id 23490 gi 51860766 } , 23491 { 23492 from 25406459 , 23493 to 25406562 , 23494 strand plus , 23495 id 23496 gi 51860766 } , 23497 { 23498 from 25406636 , 23499 to 25406728 , 23500 strand plus , 23501 id 23502 gi 51860766 } , 23503 { 23504 from 25406812 , 23505 to 25406914 , 23506 strand plus , 23507 id 23508 gi 51860766 } , 23509 { 23510 from 25406999 , 23511 to 25407136 , 23512 strand plus , 23513 id 23514 gi 51860766 } , 23515 { 23516 from 25407221 , 23517 to 25407421 , 23518 strand plus , 23519 id 23520 gi 51860766 } , 23521 { 23522 from 25407862 , 23523 to 25407897 , 23524 strand plus , 23525 id 23526 gi 51860766 } } } , 23527 seqs { 23528 whole 23529 gi 11993939 } } } } } } , 23530 { 23531 type genomic , 23532 heading "Reference" , 23533 accession "NT_039206" , 23534 version 3 , 23535 seqs { 23536 int { 23537 from 2857415 , 23538 to 2876844 , 23539 strand plus , 23540 id 23541 gi 51706164 } } , 23542 products { 23543 { 23544 type mRNA , 23545 heading "Reference" , 23546 accession "NM_007379" , 23547 version 1 , 23548 genomic-coords { 23549 mix { 23550 int { 23551 from 2857415 , 23552 to 2857480 , 23553 strand plus , 23554 id 23555 gi 51706164 } , 23556 int { 23557 from 2860641 , 23558 to 2860734 , 23559 strand plus , 23560 id 23561 gi 51706164 } , 23562 int { 23563 from 2861743 , 23564 to 2861854 , 23565 strand plus , 23566 id 23567 gi 51706164 } , 23568 int { 23569 from 2861939 , 23570 to 2862102 , 23571 strand plus , 23572 id 23573 gi 51706164 } , 23574 int { 23575 from 2862327 , 23576 to 2862454 , 23577 strand plus , 23578 id 23579 gi 51706164 } , 23580 int { 23581 from 2862609 , 23582 to 2862719 , 23583 strand plus , 23584 id 23585 gi 51706164 } , 23586 int { 23587 from 2862954 , 23588 to 2863172 , 23589 strand plus , 23590 id 23591 gi 51706164 } , 23592 int { 23593 from 2863535 , 23594 to 2863902 , 23595 strand plus , 23596 id 23597 gi 51706164 } , 23598 int { 23599 from 2864144 , 23600 to 2864303 , 23601 strand plus , 23602 id 23603 gi 51706164 } , 23604 int { 23605 from 2865013 , 23606 to 2865141 , 23607 strand plus , 23608 id 23609 gi 51706164 } , 23610 int { 23611 from 2865234 , 23612 to 2865398 , 23613 strand plus , 23614 id 23615 gi 51706164 } , 23616 int { 23617 from 2865475 , 23618 to 2865571 , 23619 strand plus , 23620 id 23621 gi 51706164 } , 23622 int { 23623 from 2865890 , 23624 to 2866063 , 23625 strand plus , 23626 id 23627 gi 51706164 } , 23628 int { 23629 from 2866133 , 23630 to 2866235 , 23631 strand plus , 23632 id 23633 gi 51706164 } , 23634 int { 23635 from 2866310 , 23636 to 2866424 , 23637 strand plus , 23638 id 23639 gi 51706164 } , 23640 int { 23641 from 2866538 , 23642 to 2866728 , 23643 strand plus , 23644 id 23645 gi 51706164 } , 23646 int { 23647 from 2866876 , 23648 to 2867026 , 23649 strand plus , 23650 id 23651 gi 51706164 } , 23652 int { 23653 from 2867103 , 23654 to 2867307 , 23655 strand plus , 23656 id 23657 gi 51706164 } , 23658 int { 23659 from 2867446 , 23660 to 2867610 , 23661 strand plus , 23662 id 23663 gi 51706164 } , 23664 int { 23665 from 2867712 , 23666 to 2867892 , 23667 strand plus , 23668 id 23669 gi 51706164 } , 23670 int { 23671 from 2867972 , 23672 to 2868184 , 23673 strand plus , 23674 id 23675 gi 51706164 } , 23676 int { 23677 from 2869170 , 23678 to 2869366 , 23679 strand plus , 23680 id 23681 gi 51706164 } , 23682 int { 23683 from 2869455 , 23684 to 2869637 , 23685 strand plus , 23686 id 23687 gi 51706164 } , 23688 int { 23689 from 2869833 , 23690 to 2870017 , 23691 strand plus , 23692 id 23693 gi 51706164 } , 23694 int { 23695 from 2870124 , 23696 to 2870244 , 23697 strand plus , 23698 id 23699 gi 51706164 } , 23700 int { 23701 from 2870520 , 23702 to 2870756 , 23703 strand plus , 23704 id 23705 gi 51706164 } , 23706 int { 23707 from 2870836 , 23708 to 2871042 , 23709 strand plus , 23710 id 23711 gi 51706164 } , 23712 int { 23713 from 2871295 , 23714 to 2871397 , 23715 strand plus , 23716 id 23717 gi 51706164 } , 23718 int { 23719 from 2871480 , 23720 to 2871799 , 23721 strand plus , 23722 id 23723 gi 51706164 } , 23724 int { 23725 from 2871874 , 23726 to 2872087 , 23727 strand plus , 23728 id 23729 gi 51706164 } , 23730 int { 23731 from 2872174 , 23732 to 2872279 , 23733 strand plus , 23734 id 23735 gi 51706164 } , 23736 int { 23737 from 2872371 , 23738 to 2872482 , 23739 strand plus , 23740 id 23741 gi 51706164 } , 23742 int { 23743 from 2872572 , 23744 to 2872632 , 23745 strand plus , 23746 id 23747 gi 51706164 } , 23748 int { 23749 from 2872715 , 23750 to 2872889 , 23751 strand plus , 23752 id 23753 gi 51706164 } , 23754 int { 23755 from 2872970 , 23756 to 2873085 , 23757 strand plus , 23758 id 23759 gi 51706164 } , 23760 int { 23761 from 2873167 , 23762 to 2873314 , 23763 strand plus , 23764 id 23765 gi 51706164 } , 23766 int { 23767 from 2873459 , 23768 to 2873582 , 23769 strand plus , 23770 id 23771 gi 51706164 } , 23772 int { 23773 from 2873717 , 23774 to 2873849 , 23775 strand plus , 23776 id 23777 gi 51706164 } , 23778 int { 23779 from 2873953 , 23780 to 2874070 , 23781 strand plus , 23782 id 23783 gi 51706164 } , 23784 int { 23785 from 2874195 , 23786 to 2874373 , 23787 strand plus , 23788 id 23789 gi 51706164 } , 23790 int { 23791 from 2874615 , 23792 to 2874756 , 23793 strand plus , 23794 id 23795 gi 51706164 } , 23796 int { 23797 from 2874856 , 23798 to 2874990 , 23799 strand plus , 23800 id 23801 gi 51706164 } , 23802 int { 23803 from 2875083 , 23804 to 2875186 , 23805 strand plus , 23806 id 23807 gi 51706164 } , 23808 int { 23809 from 2875260 , 23810 to 2875352 , 23811 strand plus , 23812 id 23813 gi 51706164 } , 23814 int { 23815 from 2875436 , 23816 to 2875538 , 23817 strand plus , 23818 id 23819 gi 51706164 } , 23820 int { 23821 from 2875623 , 23822 to 2875760 , 23823 strand plus , 23824 id 23825 gi 51706164 } , 23826 int { 23827 from 2875845 , 23828 to 2876045 , 23829 strand plus , 23830 id 23831 gi 51706164 } , 23832 int { 23833 from 2876486 , 23834 to 2876844 , 23835 strand plus , 23836 id 23837 gi 51706164 } } } , 23838 seqs { 23839 whole 23840 gi 11993938 } , 23841 products { 23842 { 23843 type peptide , 23844 heading "Reference" , 23845 accession "NP_031405" , 23846 version 1 , 23847 genomic-coords { 23848 packed-int { 23849 { 23850 from 2857415 , 23851 to 2857480 , 23852 strand plus , 23853 id 23854 gi 51706164 } , 23855 { 23856 from 2860641 , 23857 to 2860734 , 23858 strand plus , 23859 id 23860 gi 51706164 } , 23861 { 23862 from 2861743 , 23863 to 2861854 , 23864 strand plus , 23865 id 23866 gi 51706164 } , 23867 { 23868 from 2861939 , 23869 to 2862102 , 23870 strand plus , 23871 id 23872 gi 51706164 } , 23873 { 23874 from 2862327 , 23875 to 2862454 , 23876 strand plus , 23877 id 23878 gi 51706164 } , 23879 { 23880 from 2862609 , 23881 to 2862719 , 23882 strand plus , 23883 id 23884 gi 51706164 } , 23885 { 23886 from 2862954 , 23887 to 2863172 , 23888 strand plus , 23889 id 23890 gi 51706164 } , 23891 { 23892 from 2863535 , 23893 to 2863902 , 23894 strand plus , 23895 id 23896 gi 51706164 } , 23897 { 23898 from 2864144 , 23899 to 2864303 , 23900 strand plus , 23901 id 23902 gi 51706164 } , 23903 { 23904 from 2865013 , 23905 to 2865141 , 23906 strand plus , 23907 id 23908 gi 51706164 } , 23909 { 23910 from 2865234 , 23911 to 2865398 , 23912 strand plus , 23913 id 23914 gi 51706164 } , 23915 { 23916 from 2865475 , 23917 to 2865571 , 23918 strand plus , 23919 id 23920 gi 51706164 } , 23921 { 23922 from 2865890 , 23923 to 2866063 , 23924 strand plus , 23925 id 23926 gi 51706164 } , 23927 { 23928 from 2866133 , 23929 to 2866235 , 23930 strand plus , 23931 id 23932 gi 51706164 } , 23933 { 23934 from 2866310 , 23935 to 2866424 , 23936 strand plus , 23937 id 23938 gi 51706164 } , 23939 { 23940 from 2866538 , 23941 to 2866728 , 23942 strand plus , 23943 id 23944 gi 51706164 } , 23945 { 23946 from 2866876 , 23947 to 2867026 , 23948 strand plus , 23949 id 23950 gi 51706164 } , 23951 { 23952 from 2867103 , 23953 to 2867307 , 23954 strand plus , 23955 id 23956 gi 51706164 } , 23957 { 23958 from 2867446 , 23959 to 2867610 , 23960 strand plus , 23961 id 23962 gi 51706164 } , 23963 { 23964 from 2867712 , 23965 to 2867892 , 23966 strand plus , 23967 id 23968 gi 51706164 } , 23969 { 23970 from 2867972 , 23971 to 2868184 , 23972 strand plus , 23973 id 23974 gi 51706164 } , 23975 { 23976 from 2869170 , 23977 to 2869366 , 23978 strand plus , 23979 id 23980 gi 51706164 } , 23981 { 23982 from 2869455 , 23983 to 2869637 , 23984 strand plus , 23985 id 23986 gi 51706164 } , 23987 { 23988 from 2869833 , 23989 to 2870017 , 23990 strand plus , 23991 id 23992 gi 51706164 } , 23993 { 23994 from 2870124 , 23995 to 2870244 , 23996 strand plus , 23997 id 23998 gi 51706164 } , 23999 { 24000 from 2870520 , 24001 to 2870756 , 24002 strand plus , 24003 id 24004 gi 51706164 } , 24005 { 24006 from 2870836 , 24007 to 2871042 , 24008 strand plus , 24009 id 24010 gi 51706164 } , 24011 { 24012 from 2871295 , 24013 to 2871397 , 24014 strand plus , 24015 id 24016 gi 51706164 } , 24017 { 24018 from 2871480 , 24019 to 2871799 , 24020 strand plus , 24021 id 24022 gi 51706164 } , 24023 { 24024 from 2871874 , 24025 to 2872087 , 24026 strand plus , 24027 id 24028 gi 51706164 } , 24029 { 24030 from 2872174 , 24031 to 2872279 , 24032 strand plus , 24033 id 24034 gi 51706164 } , 24035 { 24036 from 2872371 , 24037 to 2872482 , 24038 strand plus , 24039 id 24040 gi 51706164 } , 24041 { 24042 from 2872572 , 24043 to 2872632 , 24044 strand plus , 24045 id 24046 gi 51706164 } , 24047 { 24048 from 2872715 , 24049 to 2872889 , 24050 strand plus , 24051 id 24052 gi 51706164 } , 24053 { 24054 from 2872970 , 24055 to 2873085 , 24056 strand plus , 24057 id 24058 gi 51706164 } , 24059 { 24060 from 2873167 , 24061 to 2873314 , 24062 strand plus , 24063 id 24064 gi 51706164 } , 24065 { 24066 from 2873459 , 24067 to 2873582 , 24068 strand plus , 24069 id 24070 gi 51706164 } , 24071 { 24072 from 2873717 , 24073 to 2873849 , 24074 strand plus , 24075 id 24076 gi 51706164 } , 24077 { 24078 from 2873953 , 24079 to 2874070 , 24080 strand plus , 24081 id 24082 gi 51706164 } , 24083 { 24084 from 2874195 , 24085 to 2874373 , 24086 strand plus , 24087 id 24088 gi 51706164 } , 24089 { 24090 from 2874615 , 24091 to 2874756 , 24092 strand plus , 24093 id 24094 gi 51706164 } , 24095 { 24096 from 2874856 , 24097 to 2874990 , 24098 strand plus , 24099 id 24100 gi 51706164 } , 24101 { 24102 from 2875083 , 24103 to 2875186 , 24104 strand plus , 24105 id 24106 gi 51706164 } , 24107 { 24108 from 2875260 , 24109 to 2875352 , 24110 strand plus , 24111 id 24112 gi 51706164 } , 24113 { 24114 from 2875436 , 24115 to 2875538 , 24116 strand plus , 24117 id 24118 gi 51706164 } , 24119 { 24120 from 2875623 , 24121 to 2875760 , 24122 strand plus , 24123 id 24124 gi 51706164 } , 24125 { 24126 from 2875845 , 24127 to 2876045 , 24128 strand plus , 24129 id 24130 gi 51706164 } , 24131 { 24132 from 2876486 , 24133 to 2876521 , 24134 strand plus , 24135 id 24136 gi 51706164 } } } , 24137 seqs { 24138 whole 24139 gi 11993939 } } } } } } } , 24140 properties { 24141 { 24142 type comment , 24143 label "Nomenclature" , 24144 version 0 , 24145 source { 24146 { 24147 anchor "Mouse Genome Informatics" } } , 24148 properties { 24149 { 24150 type property , 24151 label "Official Symbol" , 24152 text "Abca2" , 24153 version 0 } , 24154 { 24155 type property , 24156 label "Official Full Name" , 24157 text "ATP-binding cassette, sub-family A (ABC1), member 2" , 24158 version 0 } } } , 24159 { 24160 type comment , 24161 heading "GeneOntology" , 24162 version 0 , 24163 source { 24164 { 24165 pre-text "Provided by" , 24166 anchor "MGI" , 24167 url "http://www.informatics.jax.org/" } } , 24168 comment { 24169 { 24170 type comment , 24171 label "Function" , 24172 version 0 , 24173 comment { 24174 { 24175 type comment , 24176 version 0 , 24177 source { 24178 { 24179 src { 24180 db "GO" , 24181 tag 24182 id 5524 } , 24183 anchor "ATP binding" , 24184 post-text "evidence: IEA" } } } , 24185 { 24186 type comment , 24187 version 0 , 24188 source { 24189 { 24190 src { 24191 db "GO" , 24192 tag 24193 id 16887 } , 24194 anchor "ATPase activity" , 24195 post-text "evidence: IEA" } } } , 24196 { 24197 type comment , 24198 version 0 , 24199 refs { 24200 pmid 12466851 } , 24201 source { 24202 { 24203 src { 24204 db "GO" , 24205 tag 24206 id 5215 } , 24207 anchor "transporter activity" , 24208 post-text "evidence: ISS" } } } } } , 24209 { 24210 type comment , 24211 label "Process" , 24212 version 0 , 24213 comment { 24214 { 24215 type comment , 24216 version 0 , 24217 source { 24218 { 24219 src { 24220 db "GO" , 24221 tag 24222 id 8203 } , 24223 anchor "cholesterol metabolism" , 24224 post-text "evidence: ISS" } } } , 24225 { 24226 type comment , 24227 version 0 , 24228 source { 24229 { 24230 src { 24231 db "GO" , 24232 tag 24233 id 6810 } , 24234 anchor "transport" , 24235 post-text "evidence: IEA" } } } } } , 24236 { 24237 type comment , 24238 label "Component" , 24239 version 0 , 24240 comment { 24241 { 24242 type comment , 24243 version 0 , 24244 refs { 24245 pmid 12466851 } , 24246 source { 24247 { 24248 src { 24249 db "GO" , 24250 tag 24251 id 16021 } , 24252 anchor "integral to membrane" , 24253 post-text "evidence: TAS" } } } , 24254 { 24255 type comment , 24256 version 0 , 24257 source { 24258 { 24259 src { 24260 db "GO" , 24261 tag 24262 id 5765 } , 24263 anchor "lysosomal membrane" , 24264 post-text "evidence: ISS" } } } } } } } } , 24265 homology { 24266 { 24267 type comment , 24268 heading "Human, Rat" , 24269 version 0 , 24270 source { 24271 { 24272 src { 24273 db "HomoloGene" , 24274 tag 24275 id 55590 } , 24276 anchor "Map Viewer" , 24277 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=2& 24278MAPS=genes-r-org/human-chr/mouse%3A2,genes-r-org/rat-chr/mouse%3A2,genes-r-org 24279/mouse-chr2&query=e%3A11305[id]+AND+gene[obj_type]&QSTR=abca2&cmd=focus&fill=1 242800" } } } } , 24281 comments { 24282 { 24283 type comment , 24284 heading "LocusTagLink" , 24285 version 0 , 24286 source { 24287 { 24288 src { 24289 db "MGI" , 24290 tag 24291 id 99606 } } } } , 24292 { 24293 type comment , 24294 heading "RefSeq Status" , 24295 label "PROVISIONAL" , 24296 version 0 } , 24297 { 24298 type comment , 24299 version 0 , 24300 refs { 24301 pmid 14621295 , 24302 pmid 12466851 , 24303 pmid 8088782 } } , 24304 { 24305 type comment , 24306 heading "Markers (Sequence Tagged Sites/STS)" , 24307 version 0 , 24308 comment { 24309 { 24310 type comment , 24311 version 0 , 24312 source { 24313 { 24314 src { 24315 db "UniSTS" , 24316 tag 24317 id 158928 } , 24318 anchor "AI413825" , 24319 post-text "(e-PCR)" } } , 24320 comment { 24321 { 24322 type other , 24323 label "Alternate name" , 24324 text "421529" , 24325 version 0 } } } } } , 24326 { 24327 type comment , 24328 heading "NCBI Reference Sequences (RefSeq)" , 24329 version 0 , 24330 products { 24331 { 24332 type mRNA , 24333 heading "mRNA Sequence" , 24334 accession "NM_007379" , 24335 version 1 , 24336 source { 24337 { 24338 src { 24339 db "Nucleotide" , 24340 tag 24341 id 11993938 } , 24342 anchor "NM_007379" } } , 24343 seqs { 24344 whole 24345 gi 11993938 } , 24346 products { 24347 { 24348 type peptide , 24349 heading "Product" , 24350 accession "NP_031405" , 24351 version 1 , 24352 source { 24353 { 24354 src { 24355 db "Protein" , 24356 tag 24357 id 11993939 } , 24358 anchor "NP_031405" , 24359 post-text "ATP-binding cassette, sub-family A (ABC1), member 24360 2" } } , 24361 seqs { 24362 whole 24363 gi 11993939 } , 24364 comment { 24365 { 24366 type other , 24367 heading "Conserved Domains" , 24368 version 0 , 24369 source { 24370 { 24371 src { 24372 db "PROT_CDD" , 24373 tag 24374 id 11993939 } , 24375 pre-text "(2)" , 24376 anchor "summary" } } , 24377 comment { 24378 { 24379 type other , 24380 version 0 , 24381 source { 24382 { 24383 src { 24384 db "CDD" , 24385 tag 24386 id 5341 } , 24387 anchor "cd00267: ABC_ATPase; ABC (ATP-binding 24388 cassette) transporter nucleotide-binding domain" } } , 24389 comment { 24390 { 24391 type other , 24392 text "Location: 1018 - 1205 Blast Score: 389" , 24393 version 0 } , 24394 { 24395 type other , 24396 text "Location: 2051 - 2269 Blast Score: 372" , 24397 version 0 } } } } } } } } , 24398 comment { 24399 { 24400 type other , 24401 heading "Source Sequence" , 24402 version 0 , 24403 source { 24404 { 24405 src { 24406 db "Nucleotide" , 24407 tag 24408 str "X75927" } , 24409 anchor "X75927" } } , 24410 comment { 24411 { 24412 type other , 24413 version 0 } } } } } } } , 24414 { 24415 type comment , 24416 heading "Related Sequences" , 24417 version 0 , 24418 products { 24419 { 24420 type mRNA , 24421 heading "mRNA" , 24422 accession "AK129274" , 24423 version 1 , 24424 source { 24425 { 24426 src { 24427 db "Nucleotide" , 24428 tag 24429 id 37360211 } , 24430 anchor "AK129274" } } , 24431 seqs { 24432 whole 24433 gi 37360211 } , 24434 products { 24435 { 24436 type peptide , 24437 accession "BAC98084" , 24438 version 1 , 24439 source { 24440 { 24441 src { 24442 db "Protein" , 24443 tag 24444 id 37360212 } , 24445 anchor "BAC98084" } } , 24446 seqs { 24447 whole 24448 gi 37360212 } } } } , 24449 { 24450 type mRNA , 24451 heading "mRNA" , 24452 accession "X75927" , 24453 version 2 , 24454 source { 24455 { 24456 src { 24457 db "Nucleotide" , 24458 tag 24459 id 11990230 } , 24460 anchor "X75927" } } , 24461 seqs { 24462 whole 24463 gi 11990230 } , 24464 products { 24465 { 24466 type peptide , 24467 accession "CAA53531" , 24468 version 2 , 24469 source { 24470 { 24471 src { 24472 db "Protein" , 24473 tag 24474 id 11990231 } , 24475 anchor "CAA53531" } } , 24476 seqs { 24477 whole 24478 gi 11990231 } } } , 24479 comment { 24480 { 24481 type other , 24482 label "Strain" , 24483 text "DBA/2" , 24484 version 0 } } } , 24485 { 24486 type other , 24487 text "None" , 24488 version 0 , 24489 products { 24490 { 24491 type peptide , 24492 accession "P41234" , 24493 version 0 , 24494 source { 24495 { 24496 src { 24497 db "Protein" , 24498 tag 24499 id 14916951 } , 24500 anchor "P41234" } } , 24501 seqs { 24502 whole 24503 gi 14916951 } } } } } } , 24504 { 24505 type comment , 24506 heading "Additional Links" , 24507 version 0 , 24508 comment { 24509 { 24510 type comment , 24511 version 0 , 24512 source { 24513 { 24514 src { 24515 db "Evidence Viewer" , 24516 tag 24517 str "11305" } , 24518 anchor "Evidence Viewer" , 24519 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont 24520ig=NT_039206.3&gene=Abca2&lid=11305&from=2857416&to=2876845" } } } , 24521 { 24522 type comment , 24523 version 0 , 24524 source { 24525 { 24526 src { 24527 db "ModelMaker" , 24528 tag 24529 str "11305" } , 24530 anchor "ModelMaker" , 24531 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10 24532090&contig=NT_039206.3&gene=Abca2&lid=11305" } } } , 24533 { 24534 type comment , 24535 text "UniGene" , 24536 version 0 , 24537 xtra-properties { 24538 { 24539 tag "UNIGENE" , 24540 value "Mm.2210" } } , 24541 source { 24542 { 24543 src { 24544 db "UniGene" , 24545 tag 24546 str "Mm.2210" } , 24547 anchor "Mm.2210" , 24548 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=22 2454910" } } } , 24550 { 24551 type comment , 24552 version 0 , 24553 source { 24554 { 24555 src { 24556 db "HomoloGene" , 24557 tag 24558 str "11305" } , 24559 anchor "HomoloGene" , 24560 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 2456111305[loc]&TAXID=10090" } } } , 24562 { 24563 type comment , 24564 version 0 , 24565 source { 24566 { 24567 src { 24568 db "MGI" , 24569 tag 24570 id 99606 } , 24571 anchor "MGI" , 24572 url "http://www.informatics.jax.org/searches/accession_report.cg 24573i?id=MGI:99606" } } } , 24574 { 24575 type comment , 24576 version 0 , 24577 source { 24578 { 24579 src { 24580 db "Ensembl" , 24581 tag 24582 str "" } , 24583 url "http://www.ensembl.org/Mus_musculus/contigview?geneid=X7592 245847" } } } , 24585 { 24586 type comment , 24587 version 0 , 24588 source { 24589 { 24590 src { 24591 db "UCSC" , 24592 tag 24593 str "" } , 24594 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position= 24595X75927" } } } , 24596 { 24597 type comment , 24598 text "Human ABC-Transporter Proteins" , 24599 version 0 , 24600 source { 24601 { 24602 src { 24603 db "Human ABC-Transporter Proteins" , 24604 tag 24605 str "Human ABC-Transporter Proteins" } , 24606 anchor "Human ABC-Transporter Proteins" , 24607 url "http://nutrigene.4t.com/humanabc.htm" } } } } } } , 24608 unique-keys { 24609 { 24610 db "LocusID" , 24611 tag 24612 id 11305 } , 24613 { 24614 db "MGI" , 24615 tag 24616 id 99606 } } , 24617 xtra-index-terms { 24618 "LOC11305" } } 24619Entrezgene ::= { 24620 track-info { 24621 geneid 11306 , 24622 status live , 24623 create-date 24624 std { 24625 year 2003 , 24626 month 8 , 24627 day 28 , 24628 hour 21 , 24629 minute 39 , 24630 second 0 } , 24631 update-date 24632 std { 24633 year 2005 , 24634 month 4 , 24635 day 19 , 24636 hour 12 , 24637 minute 12 , 24638 second 0 } } , 24639 type protein-coding , 24640 source { 24641 genome genomic , 24642 origin natural , 24643 org { 24644 taxname "Mus musculus" , 24645 common "house mouse" , 24646 db { 24647 { 24648 db "taxon" , 24649 tag 24650 id 10090 } } , 24651 syn { 24652 "mouse" } , 24653 orgname { 24654 name 24655 binomial { 24656 genus "Mus" , 24657 species "musculus" } , 24658 lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; 24659 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; 24660 Sciurognathi; Muridae; Murinae; Mus" , 24661 gcode 1 , 24662 mgcode 2 , 24663 div "ROD" } } , 24664 subtype { 24665 { 24666 subtype chromosome , 24667 name "X" } } } , 24668 gene { 24669 locus "Abcb7" , 24670 desc "ATP-binding cassette, sub-family B (MDR/TAP), member 7" , 24671 maploc "X 39.0 cM" , 24672 syn { 24673 "Abc7" } , 24674 locus-tag "MGI:109533" } , 24675 prot { 24676 name { 24677 "ATP-binding cassette, sub-family B (MDR/TAP), member 7" , 24678 "ATP-binding cassette 7" } } , 24679 location { 24680 { 24681 display-str "X C-D" , 24682 method 24683 map-type cyto } , 24684 { 24685 display-str "X 39.0 cM" , 24686 method 24687 map-type cM } } , 24688 gene-source { 24689 src "LocusLink" , 24690 src-int 11306 , 24691 src-str2 "11306" , 24692 gene-display FALSE , 24693 locus-display FALSE , 24694 extra-terms FALSE } , 24695 locus { 24696 { 24697 type genomic , 24698 heading "Reference" , 24699 accession "NC_000086" , 24700 version 1 , 24701 seqs { 24702 int { 24703 from 95684235 , 24704 to 95817474 , 24705 strand minus , 24706 id 24707 gi 51869957 } } , 24708 products { 24709 { 24710 type mRNA , 24711 heading "Reference" , 24712 accession "XM_356348" , 24713 version 2 , 24714 genomic-coords { 24715 mix { 24716 int { 24717 from 95684235 , 24718 to 95687836 , 24719 strand minus , 24720 id 24721 gi 51869957 } , 24722 int { 24723 from 95694701 , 24724 to 95694808 , 24725 strand minus , 24726 id 24727 gi 51869957 } , 24728 int { 24729 from 95698046 , 24730 to 95698149 , 24731 strand minus , 24732 id 24733 gi 51869957 } , 24734 int { 24735 from 95699409 , 24736 to 95699580 , 24737 strand minus , 24738 id 24739 gi 51869957 } , 24740 int { 24741 from 95703347 , 24742 to 95703476 , 24743 strand minus , 24744 id 24745 gi 51869957 } , 24746 int { 24747 from 95703628 , 24748 to 95703791 , 24749 strand minus , 24750 id 24751 gi 51869957 } , 24752 int { 24753 from 95704349 , 24754 to 95704506 , 24755 strand minus , 24756 id 24757 gi 51869957 } , 24758 int { 24759 from 95705372 , 24760 to 95705546 , 24761 strand minus , 24762 id 24763 gi 51869957 } , 24764 int { 24765 from 95706530 , 24766 to 95706617 , 24767 strand minus , 24768 id 24769 gi 51869957 } , 24770 int { 24771 from 95706707 , 24772 to 95706795 , 24773 strand minus , 24774 id 24775 gi 51869957 } , 24776 int { 24777 from 95707710 , 24778 to 95707978 , 24779 strand minus , 24780 id 24781 gi 51869957 } , 24782 int { 24783 from 95708848 , 24784 to 95708980 , 24785 strand minus , 24786 id 24787 gi 51869957 } , 24788 int { 24789 from 95726912 , 24790 to 95727031 , 24791 strand minus , 24792 id 24793 gi 51869957 } , 24794 int { 24795 from 95746072 , 24796 to 95746158 , 24797 strand minus , 24798 id 24799 gi 51869957 } , 24800 int { 24801 from 95748503 , 24802 to 95748580 , 24803 strand minus , 24804 id 24805 gi 51869957 } , 24806 int { 24807 from 95817235 , 24808 to 95817474 , 24809 strand minus , 24810 id 24811 gi 51869957 } } } , 24812 seqs { 24813 whole 24814 gi 51772276 } , 24815 products { 24816 { 24817 type peptide , 24818 heading "Reference" , 24819 accession "XP_356348" , 24820 version 1 , 24821 genomic-coords { 24822 packed-int { 24823 { 24824 from 95687621 , 24825 to 95687836 , 24826 strand minus , 24827 id 24828 gi 51869957 } , 24829 { 24830 from 95694701 , 24831 to 95694808 , 24832 strand minus , 24833 id 24834 gi 51869957 } , 24835 { 24836 from 95698046 , 24837 to 95698149 , 24838 strand minus , 24839 id 24840 gi 51869957 } , 24841 { 24842 from 95699409 , 24843 to 95699580 , 24844 strand minus , 24845 id 24846 gi 51869957 } , 24847 { 24848 from 95703347 , 24849 to 95703476 , 24850 strand minus , 24851 id 24852 gi 51869957 } , 24853 { 24854 from 95703628 , 24855 to 95703791 , 24856 strand minus , 24857 id 24858 gi 51869957 } , 24859 { 24860 from 95704349 , 24861 to 95704506 , 24862 strand minus , 24863 id 24864 gi 51869957 } , 24865 { 24866 from 95705372 , 24867 to 95705546 , 24868 strand minus , 24869 id 24870 gi 51869957 } , 24871 { 24872 from 95706530 , 24873 to 95706617 , 24874 strand minus , 24875 id 24876 gi 51869957 } , 24877 { 24878 from 95706707 , 24879 to 95706795 , 24880 strand minus , 24881 id 24882 gi 51869957 } , 24883 { 24884 from 95707710 , 24885 to 95707978 , 24886 strand minus , 24887 id 24888 gi 51869957 } , 24889 { 24890 from 95708848 , 24891 to 95708980 , 24892 strand minus , 24893 id 24894 gi 51869957 } , 24895 { 24896 from 95726912 , 24897 to 95727031 , 24898 strand minus , 24899 id 24900 gi 51869957 } , 24901 { 24902 from 95746072 , 24903 to 95746158 , 24904 strand minus , 24905 id 24906 gi 51869957 } , 24907 { 24908 from 95748503 , 24909 to 95748580 , 24910 strand minus , 24911 id 24912 gi 51869957 } , 24913 { 24914 from 95817235 , 24915 to 95817474 , 24916 strand minus , 24917 id 24918 gi 51869957 } } } , 24919 seqs { 24920 whole 24921 gi 38086485 } } } } } } , 24922 { 24923 type genomic , 24924 heading "Reference" , 24925 accession "NT_039711" , 24926 version 3 , 24927 seqs { 24928 int { 24929 from 9312469 , 24930 to 9445708 , 24931 strand minus , 24932 id 24933 gi 51772331 } } , 24934 products { 24935 { 24936 type mRNA , 24937 heading "Reference" , 24938 accession "XM_356348" , 24939 version 2 , 24940 genomic-coords { 24941 mix { 24942 int { 24943 from 9312469 , 24944 to 9316070 , 24945 strand minus , 24946 id 24947 gi 51772331 } , 24948 int { 24949 from 9322935 , 24950 to 9323042 , 24951 strand minus , 24952 id 24953 gi 51772331 } , 24954 int { 24955 from 9326280 , 24956 to 9326383 , 24957 strand minus , 24958 id 24959 gi 51772331 } , 24960 int { 24961 from 9327643 , 24962 to 9327814 , 24963 strand minus , 24964 id 24965 gi 51772331 } , 24966 int { 24967 from 9331581 , 24968 to 9331710 , 24969 strand minus , 24970 id 24971 gi 51772331 } , 24972 int { 24973 from 9331862 , 24974 to 9332025 , 24975 strand minus , 24976 id 24977 gi 51772331 } , 24978 int { 24979 from 9332583 , 24980 to 9332740 , 24981 strand minus , 24982 id 24983 gi 51772331 } , 24984 int { 24985 from 9333606 , 24986 to 9333780 , 24987 strand minus , 24988 id 24989 gi 51772331 } , 24990 int { 24991 from 9334764 , 24992 to 9334851 , 24993 strand minus , 24994 id 24995 gi 51772331 } , 24996 int { 24997 from 9334941 , 24998 to 9335029 , 24999 strand minus , 25000 id 25001 gi 51772331 } , 25002 int { 25003 from 9335944 , 25004 to 9336212 , 25005 strand minus , 25006 id 25007 gi 51772331 } , 25008 int { 25009 from 9337082 , 25010 to 9337214 , 25011 strand minus , 25012 id 25013 gi 51772331 } , 25014 int { 25015 from 9355146 , 25016 to 9355265 , 25017 strand minus , 25018 id 25019 gi 51772331 } , 25020 int { 25021 from 9374306 , 25022 to 9374392 , 25023 strand minus , 25024 id 25025 gi 51772331 } , 25026 int { 25027 from 9376737 , 25028 to 9376814 , 25029 strand minus , 25030 id 25031 gi 51772331 } , 25032 int { 25033 from 9445469 , 25034 to 9445708 , 25035 strand minus , 25036 id 25037 gi 51772331 } } } , 25038 seqs { 25039 whole 25040 gi 51772276 } , 25041 products { 25042 { 25043 type peptide , 25044 heading "Reference" , 25045 accession "XP_356348" , 25046 version 1 , 25047 genomic-coords { 25048 packed-int { 25049 { 25050 from 9315855 , 25051 to 9316070 , 25052 strand minus , 25053 id 25054 gi 51772331 } , 25055 { 25056 from 9322935 , 25057 to 9323042 , 25058 strand minus , 25059 id 25060 gi 51772331 } , 25061 { 25062 from 9326280 , 25063 to 9326383 , 25064 strand minus , 25065 id 25066 gi 51772331 } , 25067 { 25068 from 9327643 , 25069 to 9327814 , 25070 strand minus , 25071 id 25072 gi 51772331 } , 25073 { 25074 from 9331581 , 25075 to 9331710 , 25076 strand minus , 25077 id 25078 gi 51772331 } , 25079 { 25080 from 9331862 , 25081 to 9332025 , 25082 strand minus , 25083 id 25084 gi 51772331 } , 25085 { 25086 from 9332583 , 25087 to 9332740 , 25088 strand minus , 25089 id 25090 gi 51772331 } , 25091 { 25092 from 9333606 , 25093 to 9333780 , 25094 strand minus , 25095 id 25096 gi 51772331 } , 25097 { 25098 from 9334764 , 25099 to 9334851 , 25100 strand minus , 25101 id 25102 gi 51772331 } , 25103 { 25104 from 9334941 , 25105 to 9335029 , 25106 strand minus , 25107 id 25108 gi 51772331 } , 25109 { 25110 from 9335944 , 25111 to 9336212 , 25112 strand minus , 25113 id 25114 gi 51772331 } , 25115 { 25116 from 9337082 , 25117 to 9337214 , 25118 strand minus , 25119 id 25120 gi 51772331 } , 25121 { 25122 from 9355146 , 25123 to 9355265 , 25124 strand minus , 25125 id 25126 gi 51772331 } , 25127 { 25128 from 9374306 , 25129 to 9374392 , 25130 strand minus , 25131 id 25132 gi 51772331 } , 25133 { 25134 from 9376737 , 25135 to 9376814 , 25136 strand minus , 25137 id 25138 gi 51772331 } , 25139 { 25140 from 9445469 , 25141 to 9445708 , 25142 strand minus , 25143 id 25144 gi 51772331 } } } , 25145 seqs { 25146 whole 25147 gi 38086485 } } } } } } } , 25148 properties { 25149 { 25150 type comment , 25151 label "Nomenclature" , 25152 version 0 , 25153 source { 25154 { 25155 anchor "Mouse Genome Informatics" } } , 25156 properties { 25157 { 25158 type property , 25159 label "Official Symbol" , 25160 text "Abcb7" , 25161 version 0 } , 25162 { 25163 type property , 25164 label "Official Full Name" , 25165 text "ATP-binding cassette, sub-family B (MDR/TAP), member 7" , 25166 version 0 } } } , 25167 { 25168 type comment , 25169 heading "GeneOntology" , 25170 version 0 , 25171 source { 25172 { 25173 pre-text "Provided by" , 25174 anchor "MGI" , 25175 url "http://www.informatics.jax.org/" } } , 25176 comment { 25177 { 25178 type comment , 25179 label "Function" , 25180 version 0 , 25181 comment { 25182 { 25183 type comment , 25184 version 0 , 25185 source { 25186 { 25187 src { 25188 db "GO" , 25189 tag 25190 id 5524 } , 25191 anchor "ATP binding" , 25192 post-text "evidence: IEA" } } } , 25193 { 25194 type comment , 25195 version 0 , 25196 source { 25197 { 25198 src { 25199 db "GO" , 25200 tag 25201 id 16887 } , 25202 anchor "ATPase activity" , 25203 post-text "evidence: IEA" } } } , 25204 { 25205 type comment , 25206 version 0 , 25207 source { 25208 { 25209 src { 25210 db "GO" , 25211 tag 25212 id 42626 } , 25213 anchor "ATPase activity, coupled to transmembrane movement 25214 of substances" , 25215 post-text "evidence: IEA" } } } , 25216 { 25217 type comment , 25218 version 0 , 25219 source { 25220 { 25221 src { 25222 db "GO" , 25223 tag 25224 id 17111 } , 25225 anchor "nucleoside-triphosphatase activity" , 25226 post-text "evidence: IEA" } } } , 25227 { 25228 type comment , 25229 version 0 , 25230 source { 25231 { 25232 src { 25233 db "GO" , 25234 tag 25235 id 166 } , 25236 anchor "nucleotide binding" , 25237 post-text "evidence: IEA" } } } } } , 25238 { 25239 type comment , 25240 label "Process" , 25241 version 0 , 25242 comment { 25243 { 25244 type comment , 25245 version 0 , 25246 source { 25247 { 25248 src { 25249 db "GO" , 25250 tag 25251 id 6810 } , 25252 anchor "transport" , 25253 post-text "evidence: IEA" } } } } } , 25254 { 25255 type comment , 25256 label "Component" , 25257 version 0 , 25258 comment { 25259 { 25260 type comment , 25261 version 0 , 25262 source { 25263 { 25264 src { 25265 db "GO" , 25266 tag 25267 id 19866 } , 25268 anchor "inner membrane" , 25269 post-text "evidence: IEA" } } } , 25270 { 25271 type comment , 25272 version 0 , 25273 source { 25274 { 25275 src { 25276 db "GO" , 25277 tag 25278 id 16021 } , 25279 anchor "integral to membrane" , 25280 post-text "evidence: IEA" } } } , 25281 { 25282 type comment , 25283 version 0 , 25284 source { 25285 { 25286 src { 25287 db "GO" , 25288 tag 25289 id 16020 } , 25290 anchor "membrane" , 25291 post-text "evidence: IEA" } } } , 25292 { 25293 type comment , 25294 version 0 , 25295 source { 25296 { 25297 src { 25298 db "GO" , 25299 tag 25300 id 5739 } , 25301 anchor "mitochondrion" , 25302 post-text "evidence: IEA" } } } } } } } } , 25303 homology { 25304 { 25305 type comment , 25306 heading "Human, Rat" , 25307 version 0 , 25308 source { 25309 { 25310 src { 25311 db "HomoloGene" , 25312 tag 25313 id 3175 } , 25314 anchor "Map Viewer" , 25315 url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=X& 25316MAPS=genes-r-org/human-chr/mouse%3AX,genes-r-org/rat-chr/mouse%3AX,genes-r-org 25317/mouse-chrX&query=e%3A11306[id]+AND+gene[obj_type]&QSTR=abcb7&cmd=focus&fill=1 253180" } } } } , 25319 comments { 25320 { 25321 type comment , 25322 heading "LocusTagLink" , 25323 version 0 , 25324 source { 25325 { 25326 src { 25327 db "MGI" , 25328 tag 25329 id 109533 } } } } , 25330 { 25331 type comment , 25332 heading "RefSeq Status" , 25333 label "MODEL" , 25334 version 0 } , 25335 { 25336 type comment , 25337 version 0 , 25338 refs { 25339 pmid 14651853 , 25340 pmid 12480705 , 25341 pmid 12477932 , 25342 pmid 11217851 , 25343 pmid 11076861 , 25344 pmid 11042159 , 25345 pmid 10922068 , 25346 pmid 10349636 , 25347 pmid 9143506 } } , 25348 { 25349 type comment , 25350 heading "Markers (Sequence Tagged Sites/STS)" , 25351 version 0 , 25352 comment { 25353 { 25354 type comment , 25355 version 0 , 25356 source { 25357 { 25358 src { 25359 db "UniSTS" , 25360 tag 25361 id 161105 } , 25362 anchor "RH124283" , 25363 post-text "(e-PCR)" } } } , 25364 { 25365 type comment , 25366 version 0 , 25367 source { 25368 { 25369 src { 25370 db "UniSTS" , 25371 tag 25372 id 178992 } , 25373 anchor "AW537380" , 25374 post-text "(e-PCR)" } } , 25375 comment { 25376 { 25377 type other , 25378 label "Alternate name" , 25379 text "953972" , 25380 version 0 } } } , 25381 { 25382 type comment , 25383 version 0 , 25384 source { 25385 { 25386 src { 25387 db "UniSTS" , 25388 tag 25389 id 181314 } , 25390 anchor "AU019072" , 25391 post-text "(e-PCR)" } } , 25392 comment { 25393 { 25394 type other , 25395 label "Alternate name" , 25396 text "359130" , 25397 version 0 } } } } } , 25398 { 25399 type comment , 25400 heading "NCBI Reference Sequences (RefSeq)" , 25401 version 0 , 25402 products { 25403 { 25404 type mRNA , 25405 heading "mRNA Sequence" , 25406 accession "XM_356348" , 25407 version 2 , 25408 source { 25409 { 25410 src { 25411 db "Nucleotide" , 25412 tag 25413 id 51772276 } , 25414 anchor "XM_356348" } } , 25415 seqs { 25416 whole 25417 gi 51772276 } , 25418 products { 25419 { 25420 type peptide , 25421 accession "XP_356348" , 25422 version 1 , 25423 source { 25424 { 25425 src { 25426 db "Protein" , 25427 tag 25428 id 38086485 } , 25429 anchor "XP_356348" } } , 25430 seqs { 25431 whole 25432 gi 38086485 } , 25433 comment { 25434 { 25435 type other , 25436 heading "Conserved Domains" , 25437 version 0 , 25438 source { 25439 { 25440 src { 25441 db "PROT_CDD" , 25442 tag 25443 id 38086485 } , 25444 pre-text "(3)" , 25445 anchor "summary" } } , 25446 comment { 25447 { 25448 type other , 25449 version 0 , 25450 source { 25451 { 25452 src { 25453 db "CDD" , 25454 tag 25455 id 5341 } , 25456 anchor "cd00267: ABC_ATPase; ABC (ATP-binding 25457 cassette) transporter nucleotide-binding domain" } } , 25458 comment { 25459 { 25460 type other , 25461 text "Location: 496 - 714 Blast Score: 577" , 25462 version 0 } } } , 25463 { 25464 type other , 25465 version 0 , 25466 source { 25467 { 25468 src { 25469 db "CDD" , 25470 tag 25471 id 14387 } , 25472 anchor "COG5265: ATM1; ABC-type transport system 25473 involved in Fe-S cluster assembly, permease and ATPase components 25474 [Posttranslational modification, protein turnover, chaperones]" } } , 25475 comment { 25476 { 25477 type other , 25478 text "Location: 234 - 729 Blast Score: 1506" , 25479 version 0 } } } , 25480 { 25481 type other , 25482 version 0 , 25483 source { 25484 { 25485 src { 25486 db "CDD" , 25487 tag 25488 id 25581 } , 25489 anchor "pfam00664: ABC_membrane; ABC transporter 25490 transmembrane region" } } , 25491 comment { 25492 { 25493 type other , 25494 text "Location: 164 - 435 Blast Score: 247" , 25495 version 0 } } } } } } } } } } } , 25496 { 25497 type comment , 25498 heading "Related Sequences" , 25499 version 0 , 25500 products { 25501 { 25502 type mRNA , 25503 heading "mRNA" , 25504 accession "AA517758" , 25505 version 1 , 25506 source { 25507 { 25508 src { 25509 db "Nucleotide" , 25510 tag 25511 id 2257282 } , 25512 anchor "AA517758" } } , 25513 seqs { 25514 whole 25515 gi 2257282 } , 25516 products { 25517 { 25518 type peptide , 25519 text "None" , 25520 version 0 } } , 25521 comment { 25522 { 25523 type other , 25524 label "Strain" , 25525 text "C57BL/6J x DBA/2J F1" , 25526 version 0 } } } , 25527 { 25528 type mRNA , 25529 heading "mRNA" , 25530 accession "AK040069" , 25531 version 1 , 25532 source { 25533 { 25534 src { 25535 db "Nucleotide" , 25536 tag 25537 id 26087598 } , 25538 anchor "AK040069" } } , 25539 seqs { 25540 whole 25541 gi 26087598 } , 25542 products { 25543 { 25544 type peptide , 25545 text "None" , 25546 version 0 } } , 25547 comment { 25548 { 25549 type other , 25550 label "Strain" , 25551 text "C57BL/6J" , 25552 version 0 } } } , 25553 { 25554 type mRNA , 25555 heading "mRNA" , 25556 accession "AK084853" , 25557 version 1 , 25558 source { 25559 { 25560 src { 25561 db "Nucleotide" , 25562 tag 25563 id 26102284 } , 25564 anchor "AK084853" } } , 25565 seqs { 25566 whole 25567 gi 26102284 } , 25568 products { 25569 { 25570 type peptide , 25571 text "None" , 25572 version 0 } } , 25573 comment { 25574 { 25575 type other , 25576 label "Strain" , 25577 text "C57BL/6J" , 25578 version 0 } } } , 25579 { 25580 type mRNA , 25581 heading "mRNA" , 25582 accession "AU019072" , 25583 version 1 , 25584 source { 25585 { 25586 src { 25587 db "Nucleotide" , 25588 tag 25589 id 3374656 } , 25590 anchor "AU019072" } } , 25591 seqs { 25592 whole 25593 gi 3374656 } , 25594 products { 25595 { 25596 type peptide , 25597 text "None" , 25598 version 0 } } , 25599 comment { 25600 { 25601 type other , 25602 label "Strain" , 25603 text "C57BL/6J" , 25604 version 0 } } } , 25605 { 25606 type mRNA , 25607 heading "mRNA" , 25608 accession "AW537380" , 25609 version 1 , 25610 source { 25611 { 25612 src { 25613 db "Nucleotide" , 25614 tag 25615 id 7179797 } , 25616 anchor "AW537380" } } , 25617 seqs { 25618 whole 25619 gi 7179797 } , 25620 products { 25621 { 25622 type peptide , 25623 text "None" , 25624 version 0 } } , 25625 comment { 25626 { 25627 type other , 25628 label "Strain" , 25629 text "C57BL/6J" , 25630 version 0 } } } , 25631 { 25632 type mRNA , 25633 heading "mRNA" , 25634 accession "BC035534" , 25635 version 1 , 25636 source { 25637 { 25638 src { 25639 db "Nucleotide" , 25640 tag 25641 id 23243450 } , 25642 anchor "BC035534" } } , 25643 seqs { 25644 whole 25645 gi 23243450 } , 25646 products { 25647 { 25648 type peptide , 25649 text "None" , 25650 version 0 } } } , 25651 { 25652 type mRNA , 25653 heading "mRNA" , 25654 accession "U43892" , 25655 version 1 , 25656 source { 25657 { 25658 src { 25659 db "Nucleotide" , 25660 tag 25661 id 1167981 } , 25662 anchor "U43892" } } , 25663 seqs { 25664 whole 25665 gi 1167981 } , 25666 products { 25667 { 25668 type peptide , 25669 accession "AAC53152" , 25670 version 1 , 25671 source { 25672 { 25673 src { 25674 db "Protein" , 25675 tag 25676 id 1167982 } , 25677 anchor "AAC53152" } } , 25678 seqs { 25679 whole 25680 gi 1167982 } } } , 25681 comment { 25682 { 25683 type other , 25684 label "Strain" , 25685 text "DBA/2" , 25686 version 0 } } } , 25687 { 25688 type other , 25689 text "None" , 25690 version 0 , 25691 products { 25692 { 25693 type peptide , 25694 accession "Q61102" , 25695 version 0 , 25696 source { 25697 { 25698 src { 25699 db "Protein" , 25700 tag 25701 id 5902709 } , 25702 anchor "Q61102" } } , 25703 seqs { 25704 whole 25705 gi 5902709 } } } } } } , 25706 { 25707 type comment , 25708 heading "Additional Links" , 25709 version 0 , 25710 comment { 25711 { 25712 type comment , 25713 version 0 , 25714 source { 25715 { 25716 src { 25717 db "Evidence Viewer" , 25718 tag 25719 str "11306" } , 25720 anchor "Evidence Viewer" , 25721 url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont 25722ig=NT_039711.3&gene=Abcb7&lid=11306&from=9312470&to=9445709" } } } , 25723 { 25724 type comment , 25725 version 0 , 25726 source { 25727 { 25728 src { 25729 db "ModelMaker" , 25730 tag 25731 str "11306" } , 25732 anchor "ModelMaker" , 25733 url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10 25734090&contig=NT_039711.3&gene=Abcb7&lid=11306" } } } , 25735 { 25736 type comment , 25737 text "UniGene" , 25738 version 0 , 25739 xtra-properties { 25740 { 25741 tag "UNIGENE" , 25742 value "Mm.262053" } } , 25743 source { 25744 { 25745 src { 25746 db "UniGene" , 25747 tag 25748 str "Mm.262053" } , 25749 anchor "Mm.262053" , 25750 url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=26 257512053" } } } , 25752 { 25753 type comment , 25754 version 0 , 25755 source { 25756 { 25757 src { 25758 db "HomoloGene" , 25759 tag 25760 str "11306" } , 25761 anchor "HomoloGene" , 25762 url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT= 2576311306[loc]&TAXID=10090" } } } , 25764 { 25765 type comment , 25766 version 0 , 25767 source { 25768 { 25769 src { 25770 db "MGI" , 25771 tag 25772 id 109533 } , 25773 anchor "MGI" , 25774 url "http://www.informatics.jax.org/searches/accession_report.cg 25775i?id=MGI:109533" } } } , 25776 { 25777 type comment , 25778 version 0 , 25779 source { 25780 { 25781 src { 25782 db "Ensembl" , 25783 tag 25784 str "" } , 25785 url "http://www.ensembl.org/Mus_musculus/contigview?geneid=BC035 25786534" } } } , 25787 { 25788 type comment , 25789 version 0 , 25790 source { 25791 { 25792 src { 25793 db "UCSC" , 25794 tag 25795 str "" } , 25796 url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position= 25797BC035534" } } } , 25798 { 25799 type comment , 25800 text "Gene Expression Database (GXD) at MGI" , 25801 version 0 , 25802 source { 25803 { 25804 src { 25805 db "Gene Expression Database (GXD) at MGI" , 25806 tag 25807 str "MGI:109533" } , 25808 anchor "MGI:109533" , 25809 url "http://www.informatics.jax.org/searches/expression_report.c 25810gi?id=MGI:109533" } } } , 25811 { 25812 type comment , 25813 text "Human ABC-Transporter Proteins" , 25814 version 0 , 25815 source { 25816 { 25817 src { 25818 db "Human ABC-Transporter Proteins" , 25819 tag 25820 str "Human ABC-Transporter Proteins" } , 25821 anchor "Human ABC-Transporter Proteins" , 25822 url "http://nutrigene.4t.com/humanabc.htm" } } } } } , 25823 { 25824 type generif , 25825 text "ABC7 positively regulates the expression of extramitochondrial 25826 thioredoxin & that of an intramitochondrial iron-sulfur-containing protein, 25827 ferrochelatase. ABC7 contributes to the production of heme during the 25828 differentiation of erythroid cells." , 25829 version 0 , 25830 refs { 25831 pmid 12480705 } , 25832 create-date 25833 str "May 23 2003 12:00AM" , 25834 update-date 25835 str "Jun 22 2003 7:07AM" } } , 25836 unique-keys { 25837 { 25838 db "LocusID" , 25839 tag 25840 id 11306 } , 25841 { 25842 db "MGI" , 25843 tag 25844 id 109533 } } , 25845 xtra-index-terms { 25846 "LOC11306" } } 25847Entrezgene ::= { 25848 track-info { 25849 geneid 171590 , 25850 status live , 25851 create-date 25852 std { 25853 year 2005 , 25854 month 4 , 25855 day 7 , 25856 hour 13 , 25857 minute 32 , 25858 second 25 } , 25859 update-date 25860 std { 25861 year 2005 , 25862 month 1 , 25863 day 18 , 25864 hour 23 , 25865 minute 7 , 25866 second 0 } } , 25867 type protein-coding , 25868 source { 25869 genome genomic , 25870 origin natural , 25871 org { 25872 taxname "Caenorhabditis elegans" , 25873 db { 25874 { 25875 db "taxon" , 25876 tag 25877 id 6239 } } , 25878 orgname { 25879 name 25880 binomial { 25881 genus "Caenorhabditis" , 25882 species "elegans" } , 25883 lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; 25884 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" , 25885 gcode 1 , 25886 mgcode 5 , 25887 div "INV" } } , 25888 subtype { 25889 { 25890 subtype chromosome , 25891 name "I" } } } , 25892 gene { 25893 locus "1A478" , 25894 maploc "I;-17.75 cM (interpolated genetic position)" , 25895 db { 25896 { 25897 db "AceView/WormGenes" , 25898 tag 25899 str "1A478" } , 25900 { 25901 db "LocusID" , 25902 tag 25903 id 171590 } , 25904 { 25905 db "WormBase" , 25906 tag 25907 str "Y74C9A.3" } } , 25908 syn { 25909 "Y74C9A.3" , 25910 "CELK05052" } , 25911 locus-tag "1A478" } , 25912 prot { 25913 name { 25914 "AD-003 protein (26.6 kD) (1A478)" } } , 25915 rna { 25916 type mRNA } , 25917 location { 25918 { 25919 display-str "I;-17.75 cM (interpolated genetic position)" , 25920 method 25921 map-type cM } } , 25922 gene-source { 25923 src "Entrez Genomes" , 25924 src-int 25167480 , 25925 src-str1 "NC_003279" , 25926 src-str2 "CE:1A478" , 25927 gene-display FALSE , 25928 locus-display FALSE , 25929 extra-terms FALSE } , 25930 locus { 25931 { 25932 type genomic , 25933 label "1A478" , 25934 accession "NC_003279" , 25935 version 2 , 25936 seqs { 25937 int { 25938 from 4220 , 25939 to 10147 , 25940 strand minus , 25941 id 25942 gi 25167480 } } , 25943 products { 25944 { 25945 type mRNA , 25946 accession "NM_058260" , 25947 version 1 , 25948 refs { 25949 pmid 9851916 } , 25950 genomic-coords { 25951 mix { 25952 int { 25953 from 10094 , 25954 to 10147 , 25955 strand minus , 25956 id 25957 gi 25167480 } , 25958 int { 25959 from 9726 , 25960 to 9845 , 25961 strand minus , 25962 id 25963 gi 25167480 } , 25964 int { 25965 from 6036 , 25966 to 6326 , 25967 strand minus , 25968 id 25969 gi 25167480 } , 25970 int { 25971 from 5194 , 25972 to 5295 , 25973 strand minus , 25974 id 25975 gi 25167480 } , 25976 int { 25977 from 4220 , 25978 to 4357 , 25979 strand minus , 25980 id 25981 gi 25167480 } } } , 25982 seqs { 25983 whole 25984 gi 17510630 } , 25985 products { 25986 { 25987 type peptide , 25988 label "AD-003 protein (26.6 kD) (1A478)" , 25989 accession "NP_490660" , 25990 version 1 , 25991 refs { 25992 pmid 9851916 } , 25993 genomic-coords { 25994 mix { 25995 int { 25996 from 10094 , 25997 to 10147 , 25998 strand minus , 25999 id 26000 gi 25167480 } , 26001 int { 26002 from 9726 , 26003 to 9845 , 26004 strand minus , 26005 id 26006 gi 25167480 } , 26007 int { 26008 from 6036 , 26009 to 6326 , 26010 strand minus , 26011 id 26012 gi 25167480 } , 26013 int { 26014 from 5194 , 26015 to 5295 , 26016 strand minus , 26017 id 26018 gi 25167480 } , 26019 int { 26020 from 4220 , 26021 to 4357 , 26022 strand minus , 26023 id 26024 gi 25167480 } } } , 26025 seqs { 26026 whole 26027 gi 17510631 } } } , 26028 comment { 26029 { 26030 type comment , 26031 text "" , 26032 version 0 } } } } , 26033 comment { 26034 { 26035 type comment , 26036 text "Title: Caenorhabditis elegans gene 1A478, AD-003 protein." , 26037 version 0 } } } } , 26038 comments { 26039 { 26040 type comment , 26041 heading "NCBI Reference Sequences (RefSeq)" , 26042 version 0 , 26043 products { 26044 { 26045 type mRNA , 26046 heading "mRNA Sequence" , 26047 accession "NM_058260" , 26048 version 1 , 26049 source { 26050 { 26051 src { 26052 db "Nucleotide" , 26053 tag 26054 id 17510630 } , 26055 anchor "NM_058260" } } , 26056 seqs { 26057 whole 26058 gi 17510630 } , 26059 products { 26060 { 26061 type peptide , 26062 heading "Product" , 26063 accession "NP_490660" , 26064 version 1 , 26065 source { 26066 { 26067 src { 26068 db "Protein" , 26069 tag 26070 id 17510631 } , 26071 anchor "NP_490660" } } , 26072 seqs { 26073 whole 26074 gi 17510631 } , 26075 comment { 26076 { 26077 type other , 26078 heading "Conserved Domains" , 26079 version 0 , 26080 source { 26081 { 26082 src { 26083 db "PROT_CDD" , 26084 tag 26085 id 17510631 } , 26086 pre-text "(1)" , 26087 anchor "summary" } } , 26088 comment { 26089 { 26090 type other , 26091 version 0 , 26092 source { 26093 { 26094 src { 26095 db "CDD" , 26096 tag 26097 id 24115 } , 26098 anchor "pfam05891: DUF858; Eukaryotic protein of 26099 unknown function (DUF858)" } } , 26100 comment { 26101 { 26102 type other , 26103 text "Location: 11 - 225 Blast Score: 824" , 26104 version 0 } } } } } } } } } } } , 26105 { 26106 type comment , 26107 heading "Related Sequences" , 26108 version 0 , 26109 products { 26110 { 26111 type genomic , 26112 heading "Genomic" , 26113 accession "AC024206" , 26114 version 1 , 26115 source { 26116 { 26117 src { 26118 db "Nucleotide" , 26119 tag 26120 id 7105656 } , 26121 anchor "AC024206" } } , 26122 seqs { 26123 whole 26124 gi 7105656 } , 26125 products { 26126 { 26127 type peptide , 26128 accession "AAF36050" , 26129 version 2 , 26130 source { 26131 { 26132 src { 26133 db "Protein" , 26134 tag 26135 id 14550391 } , 26136 anchor "AAF36050" } } , 26137 seqs { 26138 whole 26139 gi 14550391 } } } } } } , 26140 { 26141 type comment , 26142 heading "RefSeq Status" , 26143 label "Reviewed" , 26144 version 0 } } , 26145 unique-keys { 26146 { 26147 db "LocusID" , 26148 tag 26149 id 171590 } } , 26150 xtra-iq { 26151 { 26152 tag "NUCLEOTIDE" , 26153 value "7105656" } , 26154 { 26155 tag "PROTEIN" , 26156 value "14550391" } } , 26157 non-unique-keys { 26158 { 26159 db "ID" , 26160 tag 26161 id 25167480 } } } 26162Entrezgene ::= { 26163 track-info { 26164 geneid 171591 , 26165 status live , 26166 create-date 26167 std { 26168 year 2005 , 26169 month 4 , 26170 day 6 , 26171 hour 18 , 26172 minute 33 , 26173 second 30 } , 26174 update-date 26175 std { 26176 year 2005 , 26177 month 1 , 26178 day 18 , 26179 hour 23 , 26180 minute 7 , 26181 second 0 } } , 26182 type protein-coding , 26183 source { 26184 genome genomic , 26185 origin natural , 26186 org { 26187 taxname "Caenorhabditis elegans" , 26188 db { 26189 { 26190 db "taxon" , 26191 tag 26192 id 6239 } } , 26193 orgname { 26194 name 26195 binomial { 26196 genus "Caenorhabditis" , 26197 species "elegans" } , 26198 lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; 26199 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" , 26200 gcode 1 , 26201 mgcode 5 , 26202 div "INV" } } , 26203 subtype { 26204 { 26205 subtype chromosome , 26206 name "I" } } } , 26207 gene { 26208 locus "1A489" , 26209 maploc "I;-17.80 cM (interpolated genetic position)" , 26210 db { 26211 { 26212 db "AceView/WormGenes" , 26213 tag 26214 str "1A489" } , 26215 { 26216 db "LocusID" , 26217 tag 26218 id 171591 } , 26219 { 26220 db "WormBase" , 26221 tag 26222 str "Y74C9A.2" } } , 26223 syn { 26224 "Y74C9A.2" , 26225 "CELK01753" } , 26226 locus-tag "1A489" } , 26227 prot { 26228 name { 26229 "putative protein, with a coiled coil-4 domain (13.7 kD) (1A489)" } } , 26230 rna { 26231 type mRNA } , 26232 location { 26233 { 26234 display-str "I;-17.80 cM (interpolated genetic position)" , 26235 method 26236 map-type cM } } , 26237 gene-source { 26238 src "Entrez Genomes" , 26239 src-int 25167480 , 26240 src-str1 "NC_003279" , 26241 src-str2 "CE:1A489" , 26242 gene-display FALSE , 26243 locus-display FALSE , 26244 extra-terms FALSE } , 26245 locus { 26246 { 26247 type genomic , 26248 label "1A489" , 26249 accession "NC_003279" , 26250 version 2 , 26251 seqs { 26252 int { 26253 from 11640 , 26254 to 16584 , 26255 strand plus , 26256 id 26257 gi 25167480 } } , 26258 products { 26259 { 26260 type mRNA , 26261 accession "NM_058259" , 26262 version 1 , 26263 refs { 26264 pmid 9851916 } , 26265 genomic-coords { 26266 mix { 26267 int { 26268 from 11640 , 26269 to 11688 , 26270 strand plus , 26271 id 26272 gi 25167480 } , 26273 int { 26274 from 14950 , 26275 to 15159 , 26276 strand plus , 26277 id 26278 gi 25167480 } , 26279 int { 26280 from 16472 , 26281 to 16584 , 26282 strand plus , 26283 id 26284 gi 25167480 } } } , 26285 seqs { 26286 whole 26287 gi 17510628 } , 26288 products { 26289 { 26290 type peptide , 26291 label "putative protein, with a coiled coil-4 domain (13.7 kD) 26292 (1A489)" , 26293 accession "NP_490661" , 26294 version 1 , 26295 refs { 26296 pmid 9851916 , 26297 pmid 11231151 } , 26298 genomic-coords { 26299 mix { 26300 int { 26301 from 11640 , 26302 to 11688 , 26303 strand plus , 26304 id 26305 gi 25167480 } , 26306 int { 26307 from 14950 , 26308 to 15159 , 26309 strand plus , 26310 id 26311 gi 25167480 } , 26312 int { 26313 from 16472 , 26314 to 16584 , 26315 strand plus , 26316 id 26317 gi 25167480 } } } , 26318 seqs { 26319 whole 26320 gi 17510629 } } } , 26321 comment { 26322 { 26323 type comment , 26324 text "" , 26325 version 0 } } } } , 26326 comment { 26327 { 26328 type comment , 26329 text "Title: Caenorhabditis elegans essential expressed gene 1A489." , 26330 version 0 } } } } , 26331 comments { 26332 { 26333 type comment , 26334 heading "NCBI Reference Sequences (RefSeq)" , 26335 version 0 , 26336 products { 26337 { 26338 type mRNA , 26339 heading "mRNA Sequence" , 26340 accession "NM_058259" , 26341 version 1 , 26342 source { 26343 { 26344 src { 26345 db "Nucleotide" , 26346 tag 26347 id 17510628 } , 26348 anchor "NM_058259" } } , 26349 seqs { 26350 whole 26351 gi 17510628 } , 26352 products { 26353 { 26354 type peptide , 26355 heading "Product" , 26356 accession "NP_490661" , 26357 version 1 , 26358 source { 26359 { 26360 src { 26361 db "Protein" , 26362 tag 26363 id 17510629 } , 26364 anchor "NP_490661" } } , 26365 seqs { 26366 whole 26367 gi 17510629 } } } } } } , 26368 { 26369 type comment , 26370 heading "Related Sequences" , 26371 version 0 , 26372 products { 26373 { 26374 type genomic , 26375 heading "Genomic" , 26376 accession "AC024206" , 26377 version 1 , 26378 source { 26379 { 26380 src { 26381 db "Nucleotide" , 26382 tag 26383 id 7105656 } , 26384 anchor "AC024206" } } , 26385 seqs { 26386 whole 26387 gi 7105656 } , 26388 products { 26389 { 26390 type peptide , 26391 accession "AAF36049" , 26392 version 1 , 26393 source { 26394 { 26395 src { 26396 db "Protein" , 26397 tag 26398 id 7105658 } , 26399 anchor "AAF36049" } } , 26400 seqs { 26401 whole 26402 gi 7105658 } } } } } } , 26403 { 26404 type comment , 26405 heading "RefSeq Status" , 26406 label "Reviewed" , 26407 version 0 } } , 26408 unique-keys { 26409 { 26410 db "LocusID" , 26411 tag 26412 id 171591 } } , 26413 xtra-iq { 26414 { 26415 tag "NUCLEOTIDE" , 26416 value "7105656" } , 26417 { 26418 tag "PROTEIN" , 26419 value "7105658" } } , 26420 non-unique-keys { 26421 { 26422 db "ID" , 26423 tag 26424 id 25167480 } } } 26425Entrezgene ::= { 26426 track-info { 26427 geneid 171592 , 26428 status live , 26429 create-date 26430 std { 26431 year 2005 , 26432 month 4 , 26433 day 6 , 26434 hour 18 , 26435 minute 31 , 26436 second 55 } , 26437 update-date 26438 std { 26439 year 2005 , 26440 month 1 , 26441 day 18 , 26442 hour 23 , 26443 minute 7 , 26444 second 0 } } , 26445 type protein-coding , 26446 source { 26447 genome genomic , 26448 origin natural , 26449 org { 26450 taxname "Caenorhabditis elegans" , 26451 db { 26452 { 26453 db "taxon" , 26454 tag 26455 id 6239 } } , 26456 orgname { 26457 name 26458 binomial { 26459 genus "Caenorhabditis" , 26460 species "elegans" } , 26461 lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; 26462 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" , 26463 gcode 1 , 26464 mgcode 5 , 26465 div "INV" } } , 26466 subtype { 26467 { 26468 subtype chromosome , 26469 name "I" } } } , 26470 gene { 26471 locus "1A492" , 26472 maploc "I;-17.86 cM (interpolated genetic position)" , 26473 db { 26474 { 26475 db "AceView/WormGenes" , 26476 tag 26477 str "1A492" } , 26478 { 26479 db "LocusID" , 26480 tag 26481 id 171592 } , 26482 { 26483 db "WormBase" , 26484 tag 26485 str "Y74C9A.4a" } } , 26486 syn { 26487 "Y74C9A.4a" , 26488 "Y74C9A.4b" , 26489 "CELK08126" } , 26490 locus-tag "1A492" } , 26491 prot { 26492 name { 26493 "suppressor of PResenilin defect SPR-1 related; similar to co-repressor 26494 of REST RE1-silencing transcription factor (65.9 kD) (1A492)" , 26495 "suppressor of PResenilin defect SPR-1 related; similar to co-repressor 26496 of REST RE1-silencing transcription factor (65.6 kD) (1A492)" } } , 26497 location { 26498 { 26499 display-str "I;-17.86 cM (interpolated genetic position)" , 26500 method 26501 map-type cM } } , 26502 gene-source { 26503 src "Entrez Genomes" , 26504 src-int 25167480 , 26505 src-str1 "NC_003279" , 26506 src-str2 "CE:1A492" , 26507 gene-display FALSE , 26508 locus-display FALSE , 26509 extra-terms FALSE } , 26510 locus { 26511 { 26512 type genomic , 26513 label "1A492" , 26514 accession "NC_003279" , 26515 version 2 , 26516 seqs { 26517 int { 26518 from 17910 , 26519 to 26777 , 26520 strand minus , 26521 id 26522 gi 25167480 } } , 26523 products { 26524 { 26525 type mRNA , 26526 accession "NM_058261" , 26527 version 1 , 26528 refs { 26529 pmid 9851916 } , 26530 genomic-coords { 26531 mix { 26532 int { 26533 from 26732 , 26534 to 26777 , 26535 strand minus , 26536 id 26537 gi 25167480 } , 26538 int { 26539 from 26589 , 26540 to 26689 , 26541 strand minus , 26542 id 26543 gi 25167480 } , 26544 int { 26545 from 26370 , 26546 to 26523 , 26547 strand minus , 26548 id 26549 gi 25167480 } , 26550 int { 26551 from 25272 , 26552 to 25471 , 26553 strand minus , 26554 id 26555 gi 25167480 } , 26556 int { 26557 from 24928 , 26558 to 25089 , 26559 strand minus , 26560 id 26561 gi 25167480 } , 26562 int { 26563 from 24650 , 26564 to 24844 , 26565 strand minus , 26566 id 26567 gi 25167480 } , 26568 int { 26569 from 21012 , 26570 to 21138 , 26571 strand minus , 26572 id 26573 gi 25167480 } , 26574 int { 26575 from 20847 , 26576 to 20963 , 26577 strand minus , 26578 id 26579 gi 25167480 } , 26580 int { 26581 from 20270 , 26582 to 20477 , 26583 strand minus , 26584 id 26585 gi 25167480 } , 26586 int { 26587 from 19014 , 26588 to 19240 , 26589 strand minus , 26590 id 26591 gi 25167480 } , 26592 int { 26593 from 18005 , 26594 to 18114 , 26595 strand minus , 26596 id 26597 gi 25167480 } , 26598 int { 26599 from 17910 , 26600 to 17957 , 26601 strand minus , 26602 id 26603 gi 25167480 } } } , 26604 seqs { 26605 whole 26606 gi 17510632 } , 26607 products { 26608 { 26609 type peptide , 26610 label "suppressor of PResenilin defect SPR-1 related; similar to 26611 co-repressor of REST RE1-silencing transcription factor (65.9 kD) (1A492)" , 26612 accession "NP_490662" , 26613 version 1 , 26614 refs { 26615 pmid 9851916 } , 26616 genomic-coords { 26617 mix { 26618 int { 26619 from 26732 , 26620 to 26777 , 26621 strand minus , 26622 id 26623 gi 25167480 } , 26624 int { 26625 from 26589 , 26626 to 26689 , 26627 strand minus , 26628 id 26629 gi 25167480 } , 26630 int { 26631 from 26370 , 26632 to 26523 , 26633 strand minus , 26634 id 26635 gi 25167480 } , 26636 int { 26637 from 25272 , 26638 to 25471 , 26639 strand minus , 26640 id 26641 gi 25167480 } , 26642 int { 26643 from 24928 , 26644 to 25089 , 26645 strand minus , 26646 id 26647 gi 25167480 } , 26648 int { 26649 from 24650 , 26650 to 24844 , 26651 strand minus , 26652 id 26653 gi 25167480 } , 26654 int { 26655 from 21012 , 26656 to 21138 , 26657 strand minus , 26658 id 26659 gi 25167480 } , 26660 int { 26661 from 20847 , 26662 to 20963 , 26663 strand minus , 26664 id 26665 gi 25167480 } , 26666 int { 26667 from 20270 , 26668 to 20477 , 26669 strand minus , 26670 id 26671 gi 25167480 } , 26672 int { 26673 from 19014 , 26674 to 19240 , 26675 strand minus , 26676 id 26677 gi 25167480 } , 26678 int { 26679 from 18005 , 26680 to 18114 , 26681 strand minus , 26682 id 26683 gi 25167480 } , 26684 int { 26685 from 17910 , 26686 to 17957 , 26687 strand minus , 26688 id 26689 gi 25167480 } } } , 26690 seqs { 26691 whole 26692 gi 17510633 } } } , 26693 comment { 26694 { 26695 type comment , 26696 text "" , 26697 version 0 } } } , 26698 { 26699 type mRNA , 26700 accession "NM_058262" , 26701 version 1 , 26702 refs { 26703 pmid 9851916 } , 26704 genomic-coords { 26705 mix { 26706 int { 26707 from 26732 , 26708 to 26777 , 26709 strand minus , 26710 id 26711 gi 25167480 } , 26712 int { 26713 from 26589 , 26714 to 26680 , 26715 strand minus , 26716 id 26717 gi 25167480 } , 26718 int { 26719 from 26370 , 26720 to 26523 , 26721 strand minus , 26722 id 26723 gi 25167480 } , 26724 int { 26725 from 25272 , 26726 to 25471 , 26727 strand minus , 26728 id 26729 gi 25167480 } , 26730 int { 26731 from 24928 , 26732 to 25089 , 26733 strand minus , 26734 id 26735 gi 25167480 } , 26736 int { 26737 from 24650 , 26738 to 24844 , 26739 strand minus , 26740 id 26741 gi 25167480 } , 26742 int { 26743 from 21012 , 26744 to 21138 , 26745 strand minus , 26746 id 26747 gi 25167480 } , 26748 int { 26749 from 20847 , 26750 to 20963 , 26751 strand minus , 26752 id 26753 gi 25167480 } , 26754 int { 26755 from 20270 , 26756 to 20477 , 26757 strand minus , 26758 id 26759 gi 25167480 } , 26760 int { 26761 from 19014 , 26762 to 19240 , 26763 strand minus , 26764 id 26765 gi 25167480 } , 26766 int { 26767 from 18005 , 26768 to 18114 , 26769 strand minus , 26770 id 26771 gi 25167480 } , 26772 int { 26773 from 17910 , 26774 to 17957 , 26775 strand minus , 26776 id 26777 gi 25167480 } } } , 26778 seqs { 26779 whole 26780 gi 17510634 } , 26781 products { 26782 { 26783 type peptide , 26784 label "suppressor of PResenilin defect SPR-1 related; similar to 26785 co-repressor of REST RE1-silencing transcription factor (65.6 kD) (1A492)" , 26786 accession "NP_490663" , 26787 version 1 , 26788 refs { 26789 pmid 9851916 } , 26790 genomic-coords { 26791 mix { 26792 int { 26793 from 26732 , 26794 to 26777 , 26795 strand minus , 26796 id 26797 gi 25167480 } , 26798 int { 26799 from 26589 , 26800 to 26680 , 26801 strand minus , 26802 id 26803 gi 25167480 } , 26804 int { 26805 from 26370 , 26806 to 26523 , 26807 strand minus , 26808 id 26809 gi 25167480 } , 26810 int { 26811 from 25272 , 26812 to 25471 , 26813 strand minus , 26814 id 26815 gi 25167480 } , 26816 int { 26817 from 24928 , 26818 to 25089 , 26819 strand minus , 26820 id 26821 gi 25167480 } , 26822 int { 26823 from 24650 , 26824 to 24844 , 26825 strand minus , 26826 id 26827 gi 25167480 } , 26828 int { 26829 from 21012 , 26830 to 21138 , 26831 strand minus , 26832 id 26833 gi 25167480 } , 26834 int { 26835 from 20847 , 26836 to 20963 , 26837 strand minus , 26838 id 26839 gi 25167480 } , 26840 int { 26841 from 20270 , 26842 to 20477 , 26843 strand minus , 26844 id 26845 gi 25167480 } , 26846 int { 26847 from 19014 , 26848 to 19240 , 26849 strand minus , 26850 id 26851 gi 25167480 } , 26852 int { 26853 from 18005 , 26854 to 18114 , 26855 strand minus , 26856 id 26857 gi 25167480 } , 26858 int { 26859 from 17910 , 26860 to 17957 , 26861 strand minus , 26862 id 26863 gi 25167480 } } } , 26864 seqs { 26865 whole 26866 gi 17510635 } } } , 26867 comment { 26868 { 26869 type comment , 26870 text "" , 26871 version 0 } } } } , 26872 comment { 26873 { 26874 type comment , 26875 text "Title: Caenorhabditis elegans gene 1A492, suppressor of 26876 PResenilin defect SPR-1 related; similar to co-repressor of REST 26877 RE1-silencing transcription factor." , 26878 version 0 } } } } , 26879 comments { 26880 { 26881 type comment , 26882 heading "NCBI Reference Sequences (RefSeq)" , 26883 version 0 , 26884 products { 26885 { 26886 type mRNA , 26887 heading "mRNA Sequence" , 26888 accession "NM_058261" , 26889 version 1 , 26890 source { 26891 { 26892 src { 26893 db "Nucleotide" , 26894 tag 26895 id 17510632 } , 26896 anchor "NM_058261" } } , 26897 seqs { 26898 whole 26899 gi 17510632 } , 26900 products { 26901 { 26902 type peptide , 26903 heading "Product" , 26904 accession "NP_490662" , 26905 version 1 , 26906 source { 26907 { 26908 src { 26909 db "Protein" , 26910 tag 26911 id 17510633 } , 26912 anchor "NP_490662" } } , 26913 seqs { 26914 whole 26915 gi 17510633 } } } } , 26916 { 26917 type mRNA , 26918 heading "mRNA Sequence" , 26919 accession "NM_058262" , 26920 version 1 , 26921 source { 26922 { 26923 src { 26924 db "Nucleotide" , 26925 tag 26926 id 17510634 } , 26927 anchor "NM_058262" } } , 26928 seqs { 26929 whole 26930 gi 17510634 } , 26931 products { 26932 { 26933 type peptide , 26934 heading "Product" , 26935 accession "NP_490663" , 26936 version 1 , 26937 source { 26938 { 26939 src { 26940 db "Protein" , 26941 tag 26942 id 17510635 } , 26943 anchor "NP_490663" } } , 26944 seqs { 26945 whole 26946 gi 17510635 } } } } } } , 26947 { 26948 type comment , 26949 heading "Related Sequences" , 26950 version 0 , 26951 products { 26952 { 26953 type genomic , 26954 heading "Genomic" , 26955 accession "AC024206" , 26956 version 1 , 26957 source { 26958 { 26959 src { 26960 db "Nucleotide" , 26961 tag 26962 id 7105656 } , 26963 anchor "AC024206" } } , 26964 seqs { 26965 whole 26966 gi 7105656 } , 26967 products { 26968 { 26969 type peptide , 26970 accession "AAK67240" , 26971 version 1 , 26972 source { 26973 { 26974 src { 26975 db "Protein" , 26976 tag 26977 id 14550392 } , 26978 anchor "AAK67240" } } , 26979 seqs { 26980 whole 26981 gi 14550392 } } } } , 26982 { 26983 type genomic , 26984 heading "Genomic" , 26985 accession "AC024206" , 26986 version 1 , 26987 source { 26988 { 26989 src { 26990 db "Nucleotide" , 26991 tag 26992 id 7105656 } , 26993 anchor "AC024206" } } , 26994 seqs { 26995 whole 26996 gi 7105656 } , 26997 products { 26998 { 26999 type peptide , 27000 accession "AAF36052" , 27001 version 1 , 27002 source { 27003 { 27004 src { 27005 db "Protein" , 27006 tag 27007 id 7105661 } , 27008 anchor "AAF36052" } } , 27009 seqs { 27010 whole 27011 gi 7105661 } } } } } } , 27012 { 27013 type comment , 27014 heading "RefSeq Status" , 27015 label "Reviewed" , 27016 version 0 } } , 27017 unique-keys { 27018 { 27019 db "LocusID" , 27020 tag 27021 id 171592 } } , 27022 xtra-iq { 27023 { 27024 tag "NUCLEOTIDE" , 27025 value "7105656" } , 27026 { 27027 tag "PROTEIN" , 27028 value "14550392" } , 27029 { 27030 tag "PROTEIN" , 27031 value "7105661" } } , 27032 non-unique-keys { 27033 { 27034 db "ID" , 27035 tag 27036 id 25167480 } } } 27037Entrezgene ::= { 27038 track-info { 27039 geneid 171593 , 27040 status live , 27041 create-date 27042 std { 27043 year 2005 , 27044 month 4 , 27045 day 7 , 27046 hour 13 , 27047 minute 31 , 27048 second 41 } , 27049 update-date 27050 std { 27051 year 2005 , 27052 month 1 , 27053 day 18 , 27054 hour 23 , 27055 minute 7 , 27056 second 0 } } , 27057 type protein-coding , 27058 source { 27059 genome genomic , 27060 origin natural , 27061 org { 27062 taxname "Caenorhabditis elegans" , 27063 db { 27064 { 27065 db "taxon" , 27066 tag 27067 id 6239 } } , 27068 orgname { 27069 name 27070 binomial { 27071 genus "Caenorhabditis" , 27072 species "elegans" } , 27073 lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; 27074 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" , 27075 gcode 1 , 27076 mgcode 5 , 27077 div "INV" } } , 27078 subtype { 27079 { 27080 subtype chromosome , 27081 name "I" } } } , 27082 gene { 27083 locus "1A502" , 27084 maploc "I;-17.91 cM (interpolated genetic position)" , 27085 db { 27086 { 27087 db "AceView/WormGenes" , 27088 tag 27089 str "1A502" } , 27090 { 27091 db "LocusID" , 27092 tag 27093 id 171593 } , 27094 { 27095 db "WormBase" , 27096 tag 27097 str "Y74C9A.5" } } , 27098 syn { 27099 "Y74C9A.5" , 27100 "CELK09643" } , 27101 locus-tag "1A502" } , 27102 prot { 27103 name { 27104 "sestrin (1A502)" } } , 27105 rna { 27106 type mRNA } , 27107 location { 27108 { 27109 display-str "I;-17.91 cM (interpolated genetic position)" , 27110 method 27111 map-type cM } } , 27112 gene-source { 27113 src "Entrez Genomes" , 27114 src-int 25167480 , 27115 src-str1 "NC_003279" , 27116 src-str2 "CE:1A502" , 27117 gene-display FALSE , 27118 locus-display FALSE , 27119 extra-terms FALSE } , 27120 locus { 27121 { 27122 type genomic , 27123 label "1A502" , 27124 accession "NC_003279" , 27125 version 2 , 27126 seqs { 27127 int { 27128 from 28279 , 27129 to 34904 , 27130 strand minus , 27131 id 27132 gi 25167480 } } , 27133 products { 27134 { 27135 type mRNA , 27136 accession "NM_058263" , 27137 version 1 , 27138 refs { 27139 pmid 9851916 } , 27140 genomic-coords { 27141 mix { 27142 int { 27143 from 34694 , 27144 to 34904 , 27145 strand minus , 27146 id 27147 gi 25167480 } , 27148 int { 27149 from 32598 , 27150 to 32764 , 27151 strand minus , 27152 id 27153 gi 25167480 } , 27154 int { 27155 from 32411 , 27156 to 32541 , 27157 strand minus , 27158 id 27159 gi 25167480 } , 27160 int { 27161 from 31768 , 27162 to 32071 , 27163 strand minus , 27164 id 27165 gi 25167480 } , 27166 int { 27167 from 29768 , 27168 to 30423 , 27169 strand minus , 27170 id 27171 gi 25167480 } , 27172 int { 27173 from 29099 , 27174 to 29366 , 27175 strand minus , 27176 id 27177 gi 25167480 } , 27178 int { 27179 from 28915 , 27180 to 29025 , 27181 strand minus , 27182 id 27183 gi 25167480 } , 27184 int { 27185 from 28279 , 27186 to 28404 , 27187 strand minus , 27188 id 27189 gi 25167480 } } } , 27190 seqs { 27191 whole 27192 gi 17510636 } , 27193 products { 27194 { 27195 type peptide , 27196 label "sestrin (1A502)" , 27197 accession "NP_490664" , 27198 version 1 , 27199 refs { 27200 pmid 9851916 } , 27201 genomic-coords { 27202 mix { 27203 int { 27204 from 34694 , 27205 to 34904 , 27206 strand minus , 27207 id 27208 gi 25167480 } , 27209 int { 27210 from 32598 , 27211 to 32764 , 27212 strand minus , 27213 id 27214 gi 25167480 } , 27215 int { 27216 from 32411 , 27217 to 32541 , 27218 strand minus , 27219 id 27220 gi 25167480 } , 27221 int { 27222 from 31768 , 27223 to 32071 , 27224 strand minus , 27225 id 27226 gi 25167480 } , 27227 int { 27228 from 29768 , 27229 to 30423 , 27230 strand minus , 27231 id 27232 gi 25167480 } , 27233 int { 27234 from 29099 , 27235 to 29366 , 27236 strand minus , 27237 id 27238 gi 25167480 } , 27239 int { 27240 from 28915 , 27241 to 29025 , 27242 strand minus , 27243 id 27244 gi 25167480 } , 27245 int { 27246 from 28279 , 27247 to 28404 , 27248 strand minus , 27249 id 27250 gi 25167480 } } } , 27251 seqs { 27252 whole 27253 gi 17510637 } } } , 27254 comment { 27255 { 27256 type comment , 27257 text "" , 27258 version 0 } } } } , 27259 comment { 27260 { 27261 type comment , 27262 text "Title: Caenorhabditis elegans gene 1A502, sestrin." , 27263 version 0 } } } } , 27264 comments { 27265 { 27266 type comment , 27267 heading "NCBI Reference Sequences (RefSeq)" , 27268 version 0 , 27269 products { 27270 { 27271 type mRNA , 27272 heading "mRNA Sequence" , 27273 accession "NM_058263" , 27274 version 1 , 27275 source { 27276 { 27277 src { 27278 db "Nucleotide" , 27279 tag 27280 id 17510636 } , 27281 anchor "NM_058263" } } , 27282 seqs { 27283 whole 27284 gi 17510636 } , 27285 products { 27286 { 27287 type peptide , 27288 heading "Product" , 27289 accession "NP_490664" , 27290 version 1 , 27291 source { 27292 { 27293 src { 27294 db "Protein" , 27295 tag 27296 id 17510637 } , 27297 anchor "NP_490664" } } , 27298 seqs { 27299 whole 27300 gi 17510637 } , 27301 comment { 27302 { 27303 type other , 27304 heading "Conserved Domains" , 27305 version 0 , 27306 source { 27307 { 27308 src { 27309 db "PROT_CDD" , 27310 tag 27311 id 17510637 } , 27312 pre-text "(1)" , 27313 anchor "summary" } } , 27314 comment { 27315 { 27316 type other , 27317 version 0 , 27318 source { 27319 { 27320 src { 27321 db "CDD" , 27322 tag 27323 id 15933 } , 27324 anchor "pfam04636: PA26; PA26 p53-induced protein 27325 (sestrin)" } } , 27326 comment { 27327 { 27328 type other , 27329 text "Location: 88 - 644 Blast Score: 1457" , 27330 version 0 } } } } } } } } } } } , 27331 { 27332 type comment , 27333 heading "Related Sequences" , 27334 version 0 , 27335 products { 27336 { 27337 type genomic , 27338 heading "Genomic" , 27339 accession "AC024206" , 27340 version 1 , 27341 source { 27342 { 27343 src { 27344 db "Nucleotide" , 27345 tag 27346 id 7105656 } , 27347 anchor "AC024206" } } , 27348 seqs { 27349 whole 27350 gi 7105656 } , 27351 products { 27352 { 27353 type peptide , 27354 accession "AAF36051" , 27355 version 1 , 27356 source { 27357 { 27358 src { 27359 db "Protein" , 27360 tag 27361 id 7105660 } , 27362 anchor "AAF36051" } } , 27363 seqs { 27364 whole 27365 gi 7105660 } } } } } } , 27366 { 27367 type comment , 27368 heading "RefSeq Status" , 27369 label "Reviewed" , 27370 version 0 } } , 27371 unique-keys { 27372 { 27373 db "LocusID" , 27374 tag 27375 id 171593 } } , 27376 xtra-iq { 27377 { 27378 tag "NUCLEOTIDE" , 27379 value "7105656" } , 27380 { 27381 tag "PROTEIN" , 27382 value "7105660" } } , 27383 non-unique-keys { 27384 { 27385 db "ID" , 27386 tag 27387 id 25167480 } } } 27388Entrezgene ::= { 27389 track-info { 27390 geneid 171594 , 27391 status live , 27392 create-date 27393 std { 27394 year 2005 , 27395 month 4 , 27396 day 7 , 27397 hour 13 , 27398 minute 31 , 27399 second 47 } , 27400 update-date 27401 std { 27402 year 2005 , 27403 month 1 , 27404 day 18 , 27405 hour 23 , 27406 minute 7 , 27407 second 0 } } , 27408 type protein-coding , 27409 source { 27410 genome genomic , 27411 origin natural , 27412 org { 27413 taxname "Caenorhabditis elegans" , 27414 db { 27415 { 27416 db "taxon" , 27417 tag 27418 id 6239 } } , 27419 orgname { 27420 name 27421 binomial { 27422 genus "Caenorhabditis" , 27423 species "elegans" } , 27424 lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; 27425 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" , 27426 gcode 1 , 27427 mgcode 5 , 27428 div "INV" } } , 27429 subtype { 27430 { 27431 subtype chromosome , 27432 name "I" } } } , 27433 gene { 27434 locus "1A527" , 27435 maploc "I;-18.07 cM (interpolated genetic position)" , 27436 db { 27437 { 27438 db "AceView/WormGenes" , 27439 tag 27440 str "1A527" } , 27441 { 27442 db "LocusID" , 27443 tag 27444 id 171594 } , 27445 { 27446 db "WormBase" , 27447 tag 27448 str "Y48G1C.4" } } , 27449 syn { 27450 "Y48G1C.4" , 27451 "CELK05819" } , 27452 locus-tag "1A527" } , 27453 prot { 27454 name { 27455 "putative phosphatidylglycerophosphate synthase, similar to 27456 silencer-associated factor (51.7 kD) (1A527)" } } , 27457 rna { 27458 type mRNA } , 27459 location { 27460 { 27461 display-str "I;-18.07 cM (interpolated genetic position)" , 27462 method 27463 map-type cM } } , 27464 gene-source { 27465 src "Entrez Genomes" , 27466 src-int 25167480 , 27467 src-str1 "NC_003279" , 27468 src-str2 "CE:1A527" , 27469 gene-display FALSE , 27470 locus-display FALSE , 27471 extra-terms FALSE } , 27472 locus { 27473 { 27474 type genomic , 27475 label "1A527" , 27476 accession "NC_003279" , 27477 version 2 , 27478 seqs { 27479 int { 27480 from 49920 , 27481 to 54359 , 27482 strand plus , 27483 id 27484 gi 25167480 } } , 27485 products { 27486 { 27487 type mRNA , 27488 accession "NM_058265" , 27489 version 2 , 27490 refs { 27491 pmid 9851916 } , 27492 genomic-coords { 27493 mix { 27494 int { 27495 from 49920 , 27496 to 50015 , 27497 strand plus , 27498 id 27499 gi 25167480 } , 27500 int { 27501 from 50814 , 27502 to 51029 , 27503 strand plus , 27504 id 27505 gi 25167480 } , 27506 int { 27507 from 52282 , 27508 to 52409 , 27509 strand plus , 27510 id 27511 gi 25167480 } , 27512 int { 27513 from 52465 , 27514 to 52571 , 27515 strand plus , 27516 id 27517 gi 25167480 } , 27518 int { 27519 from 53265 , 27520 to 53336 , 27521 strand plus , 27522 id 27523 gi 25167480 } , 27524 int { 27525 from 53390 , 27526 to 53694 , 27527 strand plus , 27528 id 27529 gi 25167480 } , 27530 int { 27531 from 53943 , 27532 to 54359 , 27533 strand plus , 27534 id 27535 gi 25167480 } } } , 27536 seqs { 27537 whole 27538 gi 25143330 } , 27539 products { 27540 { 27541 type peptide , 27542 label "putative phosphatidylglycerophosphate synthase, similar 27543 to silencer-associated factor (51.7 kD) (1A527)" , 27544 accession "NP_490666" , 27545 version 2 , 27546 refs { 27547 pmid 9851916 , 27548 pmid 11231151 } , 27549 genomic-coords { 27550 mix { 27551 int { 27552 from 49920 , 27553 to 50015 , 27554 strand plus , 27555 id 27556 gi 25167480 } , 27557 int { 27558 from 50814 , 27559 to 51029 , 27560 strand plus , 27561 id 27562 gi 25167480 } , 27563 int { 27564 from 52282 , 27565 to 52409 , 27566 strand plus , 27567 id 27568 gi 25167480 } , 27569 int { 27570 from 52465 , 27571 to 52571 , 27572 strand plus , 27573 id 27574 gi 25167480 } , 27575 int { 27576 from 53265 , 27577 to 53336 , 27578 strand plus , 27579 id 27580 gi 25167480 } , 27581 int { 27582 from 53390 , 27583 to 53694 , 27584 strand plus , 27585 id 27586 gi 25167480 } , 27587 int { 27588 from 53943 , 27589 to 54359 , 27590 strand plus , 27591 id 27592 gi 25167480 } } } , 27593 seqs { 27594 whole 27595 gi 25143331 } } } , 27596 comment { 27597 { 27598 type comment , 27599 text "" , 27600 version 0 } } } } , 27601 comment { 27602 { 27603 type comment , 27604 text "Title: Caenorhabditis elegans essential gene 1A527, putative 27605 phosphatidylglycerophosphate synthase, similar to silencer-associated factor." , 27606 version 0 } } } } , 27607 comments { 27608 { 27609 type comment , 27610 heading "NCBI Reference Sequences (RefSeq)" , 27611 version 0 , 27612 products { 27613 { 27614 type mRNA , 27615 heading "mRNA Sequence" , 27616 accession "NM_058265" , 27617 version 2 , 27618 source { 27619 { 27620 src { 27621 db "Nucleotide" , 27622 tag 27623 id 25143330 } , 27624 anchor "NM_058265" } } , 27625 seqs { 27626 whole 27627 gi 25143330 } , 27628 products { 27629 { 27630 type peptide , 27631 heading "Product" , 27632 accession "NP_490666" , 27633 version 2 , 27634 source { 27635 { 27636 src { 27637 db "Protein" , 27638 tag 27639 id 25143331 } , 27640 anchor "NP_490666" } } , 27641 seqs { 27642 whole 27643 gi 25143331 } , 27644 comment { 27645 { 27646 type other , 27647 heading "Conserved Domains" , 27648 version 0 , 27649 source { 27650 { 27651 src { 27652 db "PROT_CDD" , 27653 tag 27654 id 25143331 } , 27655 pre-text "(1)" , 27656 anchor "summary" } } , 27657 comment { 27658 { 27659 type other , 27660 version 0 , 27661 source { 27662 { 27663 src { 27664 db "CDD" , 27665 tag 27666 id 5372 } , 27667 anchor "cd00138: PLDc; Phospholipase D" } } , 27668 comment { 27669 { 27670 type other , 27671 text "Location: 20 - 172 Blast Score: 135" , 27672 version 0 } } } } } } } } } } } , 27673 { 27674 type comment , 27675 heading "Related Sequences" , 27676 version 0 , 27677 products { 27678 { 27679 type genomic , 27680 heading "Genomic" , 27681 accession "AC024796" , 27682 version 1 , 27683 source { 27684 { 27685 src { 27686 db "Nucleotide" , 27687 tag 27688 id 7140352 } , 27689 anchor "AC024796" } } , 27690 seqs { 27691 whole 27692 gi 7140352 } , 27693 products { 27694 { 27695 type peptide , 27696 accession "AAK29892" , 27697 version 2 , 27698 source { 27699 { 27700 src { 27701 db "Protein" , 27702 tag 27703 id 16950493 } , 27704 anchor "AAK29892" } } , 27705 seqs { 27706 whole 27707 gi 16950493 } } } } } } , 27708 { 27709 type comment , 27710 heading "RefSeq Status" , 27711 label "Reviewed" , 27712 version 0 } } , 27713 unique-keys { 27714 { 27715 db "LocusID" , 27716 tag 27717 id 171594 } } , 27718 xtra-iq { 27719 { 27720 tag "NUCLEOTIDE" , 27721 value "7140352" } , 27722 { 27723 tag "PROTEIN" , 27724 value "16950493" } } , 27725 non-unique-keys { 27726 { 27727 db "ID" , 27728 tag 27729 id 25167480 } } } 27730