xref: /dports/biology/bowtie2/bowtie2-2.4.4/example/reads/longreads.fq

@r1
CCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACACGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCC
+
7%&%E,3@->*/4>0):4)17/4A=H<3!72"$97HDB(*66B(,&$+41&A,8+=,7/216,C=2#B6!>)"?&D44/6+@))30A91BA&=@(%0&-E.1-=959!B,",,#FA94,7.B+-)2@5H;6E**#EA&;"3F920A>1:<:8F-1.<A4.-/HE$02%1>;0HA6.*@(=37<:.E93+;52+8
@r2
AAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACANTGAGGGNAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAAC
+
60./".G76C,0220H8@4B)"+&F2,0>$+%%%.&@><*%.=!!%G&$GB"+!*G)5<!;&!C?<(:7<<2'5?,<(?0.3)<?5%B@+6>G.B&B4D0D>D93B?H9"47!G$G50)AF(/A:005$*@,3>0F0'!3H<<B'/1!;+*3?&D3H%--HG*7,+#CH;.6)F!$4$FH;,?H:/-86!+7>93E,C1@,/.)H+8@C*(7/:4)*E2823.+>&EE/#A2A:*3>7(52@#,9-=@$$4)H,/F"9$!$EG%=0.@B>1@H7*+;682>@$D@/@(*6F2;66#AFBE4-45E*04-6=75
@r3
TGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCANGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAANTGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCTGTTCGCGGTACTGGAGGNGGCGGCGCAACGTCGCCAGCTGTGTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACANCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTNAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGNCTGNAGTGAGTGGGAAGAGAGCGCCACGGACTGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGACAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAANCAGGCAATCGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGG
+
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
@r4
AAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCT
+
F(32>77B22+D/$%<D<BF)<<+HH#CB9+&28:!4C.)83"&5'36::G;4=9CCF.*1.8B
@r5
TTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGANGGAGGATGATGCCCGGCCGGAGGTGCTGCGTNGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCCGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGAC
+
40:D:7'%!,$(/0E#->?AF1F3'&'-:6?,F6D*(F<:<?/4#<?E07B1#,&>:HA#5H.:E6+C#2D.:0'92%-:@A6C?9F'1$=;EF*:(=0*#3/.130)D01=B"&<)4!"!>@#C>"8E40#$$G-D7*=4?A1!6!B2%'+@9<HF!"1.G6)C?5$4,D(B@H?)@(,G.&9>:$'2#%BF82.6D:#F-,.'?/.(1;F#)?5#-8"39A$D7'CE2:%:,68G8'>E&H@:"2';+(>-HB($+CD:3*-9C.2F5FG9H55&-7D-%-5C.#666(&@@6FA=##(&D.-5A-9(@)?38F#;C+#D1&3-A;+=CEE-81.-@!8!FD85CF8??B=8,+$<3=6A,?225.'=)<F#9<;4(E<A92)@5F,9E,C3+>82%/)56,!8E*@F$DE(&5-,!H;1:!>:)=-0><'D3C
@r6
TTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGAGAACGNCTTCCGAAAGAGCTCGGCTATGCGCTGCAGCATCAACTGAGGTTGGTAATAA
+
F5?!>A5%3?G082?G=E%E0806?G&EEF1-98"82CE+C%7#1:";:*4H?>:8=@#+,9"F&<C8.'(;B;5-!*=+7F?4>)D8)<F2>35C,=(&@9C53CE&<D(>+*'F%<D0629"!715:"GC39H!B35)
@r7
AATCTTTTCATCGCCAATAAAAGTGGCTATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCNTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTNATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTANTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATTCATTGGANGCCATCCTTCCATCAT
+
7EB9AF31B0@B;(,F:48D7!AG&6?2<6/0%"1%1=@E:C1;.%$:,?'.4CFH2HBE3?4F%&;A6-$86/.<C8-8%:*/H'!=.@3!<5B?0C!:D%A5*-:62!0%@#"$64!+93/0<<&7#/=+AAA.'/=462(!0,-:4,1G!5#A<1<*>:'14F#%4E1B'=$+F(:@(*@C&(($68))1497!3'E0=:=$@"9!+=1,G5*&9<,D*-9$)CB++/"EG!6&#.&,=5;"=*'C6&*)=<E*B)C6A9,H8)H)B36+2-C>=5"D4E05E;5F%28!6!?!C&<3"45@D:H&,-(BA>#;';7C)*D)7)8:-=*.@6@<B)$H764<BEF/$ECC&11CE3'(E@(02#11,?":(2G0E>D'.
@r8
GAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCA
+
G$G6<+ED.H7GA%%#F4;43$@6>BFB8?)A=,56%,E1-210G?'<-@G-?.D0-3,")$2"-*!6;%32=D=D!(E+*@,A)A#--?<%B=';4G.'.7)).G7#$%+*C?.1C#DF1-FA-)H?4+2DD$0*)%-++"$.%'??4@EC2G,;/.?3"'
@r9
TCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCNCAGGTGAGAACATCCCTGCCTGAACGTGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTNACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACA
+
&HH!)D30>#98#F#>8>B18BA=#A;;,:>D@*'%35H3=%)F$$"?'"'H/7.(,;$)(6=:-G)89C%DG=-B&C9;;$21!<8::.34E""A,+G$$@9,D51%>.F9//7"+*!*4D0*1F/))'3#&?&@+./>:!2*A#@DG?/DF#H<#69%$7:6&1@F68FC!1"!8HH%&6A#FG$#$6E!*;%8$'F$@"!0)HG+/&8-/:7&&5<E;4(CF4:5-)?151-<.<'@'"(H-'3B8ADA&">8..AB#A"/=,;F,0/+">AB"-H*/&@BH/6HG),>&95<D<=0>*;%=,EEF607)E#2#A7(>H-8B0;D4(//<B8'B-G%<:H=@,1&06=(2?;?=E'.'64-?.'D#@6$HEBB!A9
@r10
CNANCNNTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGACGTCTACCGCCCATGACAGGNAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCNCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGA
+
*%*$(""+!&&'$(#"#+%"(('++&&+')*$&$$+%(#*%#+%#(""!%""&$'(#()'%*#+*(&%)$!"&')')()*(+)")&*+)++)#$#(*!""(%&')+('!&)&$*!$*#)*)!)(%)*(!+!#$&&)$#!'&'%'$"#&+!$"&((#"&'#$!&)%'!%(%+++#(('')%!$!(*)%$!&*!##)!)"$!!!&&$(('$$)$*+$*$(**"(&$$((##!"&")(#&+$&'"%%$)'#(")#!)!%
@r11
GNANTCGAAGAATTACAGCGCAANACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATNAAAATTTTCCGGTTTAAGGCGTTTCCGNTCCTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCC
+
(!%&)#+%'$!'&*#&)"(&$"'"(+%$%+!$#!**")+&+*&+"()"$"+!#&&("%'*$!)"$$&'&)')!&*!%*)$!&+!*!+$)$#(!''&$*$$&((!+"%(%'&$&&*)()#"(#%!%)%"$#*'&*%%!('(!"()+%+)($&+!'*"%&#$''&))*#)#'%#"+#(#"""+&"'
@r12
CCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGNGAACACCTGTACCGNNTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTGCTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCNATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTANCGGTCAGCTTTCCG
+
13EG2='(#9%%+>4B3>5;1%..4E5-'C80"4:,D5.632698?4(53)6<#6>$A827;1"H*:'G,HD%3.6"/H@>912B;942$+!BBA'H,3=0(=$FHA5<)>8'>E2E28%$@=F<ADC'($)0D9=9?'$?:54HH0)"%:8(?0/:$%;>'$'A>=-=:#+>4<4"C&!'D5&E7!$">?C'-G7C*#4-1,05&;E<9)":76E5;-$D+/-#C.%/#';<!0#D;72DE7F>65@79;=H#!.1G)3<@$>)&:$5(&,='>:B10-?53":F=C8*!34$':.-DF83?'!+1-@=;=(+5BB8-:@%G3?/H8G"<D454/9E6GEE<A"0$="EDH$EF8C)+2D:*=G7:9;**D"F70:5GB(-0-&9?%?%D31)B&%#!%-%67.@%+#,)E=FA-+0)@/D?-))#B-H?)AB<D"4,9%+">4?@B)D"%$
@r13
GCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAACCGCAGCACGTTCCTGCATACGACGTGTCTNCGGCTCTACCATATCTCCTATGAGCNACGTGTT
+
700!&FAA'3FF(D<?C2/7!-#H?BB8C27!7'G-#*1<B.)6"A9F@245-?@1&!+A.FD%:D:!<("@8>9%:D#*FFE8;?,DH%"(0:31:4%3/@%!?09>#6,36E2C87"H?4@.H1B?E:DF6%4;7C&1F5<,+%(4B:83"'*%52G?7!B83D@GF85!F<F*.+<4!2(!)<#8#H%/:H<E9"&?67*'*DG,D-?0B7&6H&=5F3*$A"4%#D2C5E$;F<7>(,GB@
@r14
TCCCTTCACCACGGNGAAAGTCTATCTCTCACAAATTCCGGGACTNGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGNGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTNAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGNCACTTTCTGCNGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGNCCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCNGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTGATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCNATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATANCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGNTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTTGGGGATCACCCGGAACAGCCNATGTTTTTTNGAGCGTTTATANACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGNTATCGACATTTCTGCACCATTCCGGCGGGTATA
+
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
@r15
GATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCANATCGACGNATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCG
+
)$+$!##(!!'#(#!%(%%)'!$+#!*'$&*&#!())&($&'(+)'#))$$&!+*(("!%)*$#'#('&&+##)%''+$+*'#$&*)(+#!$"*(""'%'$&
@r16
TCAGCGGCACCGCCNTCGGGATTTTCACCACATCAATGGGGTAAC
+
/G(6/G?>6BF?,53#F;673/CC7*D+"$E')A"%)/=+0=E!0
@r17
TCTCGTGCTGAAGTGGCNGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCNGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCT
+
H'5$A0@.1;'FHBD7+91F,<;(%3D5;?E!F7:@$+'*$2?=1&.FD!/.G?EH<2%6<=$@A79:96D-''A.7!@C7-6,!5A/!E>%3%>1;3&0:+3"01:(7,HD:63!1&C"$&!*2?'E.916AD&D;#,7?56%.G=D.%EF/?EH<6?.$@"ED7+A):+9@?>1"$CA'#*G@)8;5.D8?DB*'<404!$=*$A;E'>*A&.60;0
@r18
AATGAAACGCCGATGTTTGTGGCGCAGGNCAACCAGATATTCATGAACGACGTGTTCCNGAAGCGCNTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCGTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGNTNAGTAATGTGACGATAGCTGAAAACTGTNCGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAGAGGCGGCGAGCGCGGGTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTAATGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTC
+
1#;D71@E?</@GD=1/"D!8493F/9>6,DGE'%(G<11A&+69)5$+9&(4@:+G(!5,H#9G'5*G>.>.:)/)<9E-7G*E?74)GD=E(8E5G=-+(C6'00A>A<F<(;)786.07?%'-:=:@*2;:/"15?+=!*F+9.!-#A1"5>&<H./@1-4H3F2B;2*."C&%,7.A%A9F-B@8@>D)1;H/7;2</A*&7%H,&*,G#24+.24,AD9E+%>0G0/>3AD45"C76-+08C*H;#5G$HD1+$#22/3#8B8CC7C$9C>1-9+55)*+>&(1.A%%%(:=8!.4'9-*4A&**"24:-8?"<&$C/=>C<02HB.'1@91C&<=7&B2("A4'F+$'/&@A!0"2+<.=%==3=4G<A%H8;,2F//8!B8>;C"D
@r19
AAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACACAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGNCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCCTTCGGCATACCATTTTATGACGGCGGCAGAGTCNTAAAGCACCNCATTACCC
+
7GD+#!&(#<9%43@@H2&)%9,60,D!'*8#&-"+#@&0//.<(HA-F6A(#)E+1'B"'FB$>423*8E>&E&*1.%9.F&4*)'14&<#+A/F'-*7(118@C3.A74G$,7&-;F:00;6$'(B'%1@.0+3=H.1F,C#!:&?&!@7E966*-B@C@1B2C:2D4,33-04F8&"2-93HA08.#."<;8+9E?9-9(3-G2;>(?'0;#,5&A(&>+2@&3;@7//9C@7>!B+B&9@DG-3FH"0$8$07%:!67"66(0A=?;)/F<&1&B2:,*)+B?;@-:+4E.49'.E)(0*"#A=<<-:HC$+
@r20
GCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGCCATCAATTTTTTCGTAATAGCGCAACTCTTTTACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTNTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATTCGGCTAATCAGTTCGACGCGATA
+
+1!!!0A'G/#(95,&#D#@,D(+*B5)3'G4C(>&$G;"3>09CA7H7''7.1A7<>FE,87;3',AH'#6*>$@9$$>4CG+-,$@<5#''<9&F'-?"1<.F0E<&=@,F-#+G(@3+G3(222,@#E=AC+1/9*(,D.@.-,53>/.E0"146.1%G6:1*B?%"E7@5?3.(DB=#*2@<B$$"-(42;?)*)D?*D@-.E$G1/<(+F%&8=2";F6@2B<4HG54+1,.@*(?</DC&C6@F&D7B6E.!<+,-=%CA#+?+*@C9*6D?/0%2=!H6;E4<F60BA<8;37":,=1D22$4!>@+F'F:>-4F:90B4(G28.0;$?6#F*5?!,$G7*%.%32#33<'0-5HFB5/6'#A((;)6BE20C5B-#D&D6%>1#0G/(%/-$5<&=6
@r21
ACGTCATGTCAGAGCAGAAAAAGACGTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAATCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCANAGAATATGGCGGCGATGCTGACCGGCAG
+
69*-+F%(?2G&C->A876$5DA:?)"E,?A)D)?4/%"@H;6FA1+.DFA*!B-;;E"$8E:-"(2,?B1A;#9=2AF0$.9:;-/=6!9C):$$,'BB*8)3@6.>7<$5/A3C.D>E9(6!B(:9*$:E:-.*F4:7,4GF<EC@G/D"991;169?6#CF><)#;?99(;C,(675-/4A0@;1>8
@r22
AAAATATGTAAAATCGGTAGCACCTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCCGCTCTACCATGTCTCCTATGAGCAACGTGTTAGCANAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACT
+
#,FA5HH:79/>0H!0A>CC=:*=$#'E64:HHA?72.7&A-D2A?37:%><)F="+,&FGE2BD<D?HH>%-42-C@A1(/>F%8,4G,&.*DAAAG$0-+-3&+0)H$!:F9B'(=6--',@AGG#-E%$8'0)+41(?(05/3".@2<:'@2;/-/5@!G'A9A#F080&C9*#HE:@G3A6F@;5?!D%<AB,2*-8B2F!&0-
@r23
GAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAANGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGNCAAAATATGTATCAATNCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAAGGATTCTTATCAGAAACCATATAGTAANTTAGTTACACAGGAAATT
+
(2C:).H/(H)0B$G.7)1!GFE4%).@>=*4DB;3$C,-(.@-1D9EBD%#6==0"@#2(@A/H;)62+*F@#/..07;42F*HCG6>:>5'4,8><'B()=0GA3/'.:.8!%<#?75@H6"-&3>"6-$G@>''3>#HH%145GG3E)D2>E#)D0!.)0=.,BE;FB7=#,F*<1"FH2*GE$"919G1')%(+6,1+$.4$"'5+2>09@'HD@3H@E@>,<7,C7;-(<"1//B%'+.7D%=G$9GA>%AF=&-A3("!&!8;#'@@;/.F&!H!968&H27A,1/'G%BE4!$3-==&;0-*72$A++0?@?!*E35;!;=?4"&>)0"0FA)D23'70=4BC81C:5F<D42<0=@;C/>-2;5/A&E4-*,!.@);7A'653;8!GF;)+9,<8G1D5&G6""H#%@*7&7B")?F@455(F1'%/"EGA<21)B9&5#B94%67DA#))$>1%*
@r24
ACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTT
+
7=85BHB7)8E58*C,&F,,73!?@E<%H$'@A.4-D9)56(8$B36&)7;!=?
@r25
ACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACATGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATNGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAA
+
4CF%,(:+4,F341A$9D:60);1!1,=9$"=88()?=CA'%!'0B3E?215'64(G<(3-)9,%79F26?!853*+48H1EH)0>E3/16#@@8F"):@D71//A74H7'3#:,>"+G1AF5H,",&-";,A<HH<!!./+11H1E3):FG5&:E>#0G;EF;H;);#,!G:B5&86+*7$;=+F1::'B4#&@":54&HC*AD1.A'@=?0"C6,"?5E($8=./:@%@@E.'4-!D8B;6;DA8<E?59!53=('"..303G:2D93H"<//=456,%&1-*C:G0@$,EE3A!!(
@r26
CTGCAGGTTATANTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGANGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGACGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCCCGGAGCCGGNGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCNGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAGCATTGNCCTGGGCAACCATGTTATCCAGTGAGGTGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGANTTCTGGCTTTCGGTGCCAGCATCTGAGCCACACCACCGATCACCATAGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGNGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACNTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCNGACGTCCNGCCCGNCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAA
+
;53%D('"91D,36'#!+@,":%(;%2/CC@694&12<',A58$(=A=6)E;&8,>H537?3#3</23*37266G&C>"%'$1*5%52(9%AD8#?F"201'G8=&6<:',)!DDC-C5.@6%A<;.:395%4G@;2:02E<FF&*'8-?;H!.;;4#,5<.53B(1500,B/H2%"(G80.1'G=;#:'*4'7$G!&;+!&.#+F:.G1D@%H4<6(!F@;0$F&(2&+"A0'G?E5)92">6;-<D?'F?<%0=9HA!G3"2E*F>#A!"+C6$A:37>+6-+:*>'FC$0%/F@;H+2AC%?)8&-0/,F>HFHB2$&>(9/H0<+G8&1-$"<$3$(A#++#-9:F95C8?0)<(#67H@;69?(%?382&?/3?G)F8/F5'=:1"$<3<B!H9G5=HB5F=?;F687,4%71$HA"1,G4#=*!CB@D-*&>>-DG/(F/;-6H(90.2=1@2C#.<>4:&CAHF*D>)B$64*A.BH1CD*9B-C'<3:G9?(B.>22+'*:H$'<*2>,<9&@:H*.(A5B5?<H!:1!?$"D)?!=.4F>G7?+;6*9?-3(B796@685G7)=)1$*%)@30#4F7C#:6HB>+<71$=C*EB0%-D>5+%%#)HG.!/)E!(HF0%%0$7>92<.?DE*7-?)>3B2;)7214,%A#/+?%"C((7/*1+B68BF%8G5/0/9CHB=E-B@$>B'-24B):3<G+)<:*<?<$/$984(G5:3#,1+,-/<.H7'.B-A772$B3:/%.-D6->0>*:6'C!H'(<E6;=$'<A@".9DC-!06F>HD:$:<:256G41!G;&8:=)*&6+%550:$D#8>4,-C$3/$0-(C$5$.52>BF?CA*88'8;!:+C%0(F96BG"H51=,E+0<<!F9#*2*1!/F3&D$#E:='&BC0C4&,.?="!HCB=7,0''5G>'#:<"*=>!$/FG"5;G.+3=40E?(>;7,:G$-AE31.7#,G+1?(&*>02(+60!F,(",)!@&&%(.'3C>(1(>34.!1(#(#/38BE(.BC%'(D;E!$@A9GCF,+A16-&*$?A86G;2/2#F00=+@++',"9,)(;*%*?7.C(="=9473;*58<%8#.<'9%/6;0E0"8'5D1->DD>>2*D7H.8D+,&1:B1(8&5$*G$!31-BCB@/64/0==H.;=9%4!9@&%8B0#?2G35/4&&08AD<1<G<;,@!/@?5(5:'4-'5427%'B*)B.*?62>,D'A7'G+&705<H=%E#;+588)0A+$5(:6BE#HG)(-C>";;@4,++$459)%*%H%--=,2!D-80;61:4/>D2/-#C8#?-:!-69*G:3))*:/)%E=A2<(FGC(*,,$!(:B5<
@r27
TCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCNCCGGATATCCCACAGGTGAGCCGTGNAGTTGAAGGTTTTNACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCANGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGA
+
HH@=-9<0.DBF&>2759%G4=?95(?4''(85H)8GF.,$&,:+*?=03<*;@3B75<<7=+")C5;;."+4AD586D-E#F498&=0E./G$7"'6GCB/"#H"C3-9/95?8<>5%07>:2=F*CD"C!)0?76C-EE;=G6>0A*4B:?F,A1*%'G@9C9@;D?;15787,6"EF;65"%0.27%1&>5E*8G;EA&%$+3#)&.">.;!?)@#,:-.2=HF$5*;566:4@>FA,#1#7=@2A-1*831"<8B;0=B!$7=A+ADC+(5=D2F,-AD5G?4"C9"')@G0C.1(5)D")2C2E289<=D-/CB*9-BFH93C)'D&(H2/H)>&17%4.?.D:#29"DF#)23F",5<8GD7FAG&=FB51H';)2@A7"(0/>A%.4&>+FEDA.0E<9:)HF>#*;<*C5+F/&?G@=7,,!==:$,:BB@.>C+/H450&.<C02@>#/(E.<74B;5-C?F86.'DEG<
@r28
CCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACAATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAACTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACANTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATANACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACNGAATCATGCCTGGTGTTNACATAGTAATAATTCCTTAGGTTATCGTAAGCATTTGCTATCTCCTTTTCCG
+
GH';#'/!#15<C)9&A@F%/!(H',E,3<>,!?>A<5"@@H(@/?5'9AA>-42@3=-?3(#C7?6)%F4D8EF+>@'#C-6#(,@<,%.!7??B+,:6@A9G/<>3(@*.H45B=$CC(.="@7B<'6?$G,H."E%+&''68:'H#*?1?(B33F0/&!/6HE34*:%&"F1;8!*:#7$C6E4)F!;H,#-./</@**0!9%!'*-2"??D,81%:,>1F-):&-E;!9)123B478F'<?>=*G;+=%2)06@%"0(9A0(7/H&&5>&.<5:-'E<0E1>(G''EC-4--8!4680><996*9BHH@:E@=D2E&7!'%,H94"---4/#6).&%8#@=7;3D>G;$'<11BG&'1!!?@#E+)8B6;(G),2C3@/5GG<?@.,(?<DH*5-/@''%+:H,0D'=?'!GDD?#;-0)*.BF0&-:@#>.3&%5H0!,,2H#2873!##/18$H)*+:<5;?,?!H$E'$!9043@H(:G9:!,5)#&15-.(D>HF3C'3%F>66H@%$/,-09E2<2($2+1>$B;80>1E$5A7EC!(%84#2;>%&=C,+E>3/2;)$<8C.1+C1743;$%.5=#7#808:$=B,&E)2B)!8(=?03-(#C/(/(:,.0'5?,=8!&;':4#0."3*,7-&7,#A"A+!8)A"=:!67(,3''H@-=F!61/2:7-!!4*9?F!<23=%+"!-H!+213)+FA%$F%;)353#7!CB(6+/(52*(?($<$-G-/.4+5F.(?$)%&(9ABA?GGE)2.+&B$7!0!7F2..0GA<"3<)</+/A8!:#!1//@AB8.16!#1:A/'02/#+%557!8">5D>D?C@>9.+E<&&-3$3+9>?B?/&*D#DG?&#7A>">-909CA(@6;:8!95>A&>H)$+.,-#/B+:/DCF2+='EE>/:;=D3'*,G5-+857?%G%&H."*::3>&;@#&/-#:0E<#;6;17,!&$F)#-/?4=D@(E
@r29
TATTTTNCGGGTGNNTCNTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATNGTGTGCTCCTTATTTATACATAACGAAAA
+
*)"$)#$'%$)"("('*!*+%)++')($)%***+%'##&!+''!&#'+&"$&%!&'$$("#)"%*&&&%)%)&+!('**#'&+#%'$"!*%'$$*(#%##*$"'$+$#
@r30
AGCGGTCAGGAGGCCNTTGATGCCGGACTGGCTGATGAACTTGTTAACAGCAC
+
0(&DH/-!*D#<GGG%(."@;9$#$9-8A'9??86;B<E@@E1BA5*##51$>
@r31
TNTGCCAGTTCTNCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGNGANGCNCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCTGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTA
+
'#:,6/6<*!F?<"4,B)AEH'F:43;.+@B574#005HG7?+37&BF0+";%&?$D0#G9.3%9225H;:F%-('+'?@-A?=<@>HA12$1(/:@()6;@HA$3&F@=;)-B"C>+C3<>?AF&B5'/(D$'<'>:)8@"3136$D$:F*=1>8$6D?.,%+,%C#,EB)1>G"@D=;<995:2!@1D.7D75,F541D2D8A+*&50E0EHG;GD&,+/):
@r32
CTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTTGCGCACGTTAGAGCTCGCTCGACGNTTTCTTGTTCGTAACTTCGATGTTGGTCAATNACCTTGTT
+
E2=8HF)7)::4"2'9219"%08>%?3<D#!,7,49=B8?1GE1$G!H/H>B%9!?3>;&/-(58<1.D8!!C-G1D1->49=9'':H=C8C.#.?@/$H45,AG,&@/;#
@r33
TGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATNACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGC
+
//7,#C2&;0H%%@*D0%%3:/,?3>C3=A(*#'1D74H%50;B<G$9B(0>+$*#&;3-1'7D27E19,4'-A66.C+<5B)74>&8F8</06*!69.=-2:%.552%<015C=D@;,>:1-=A/(&!&>C<<
@r34
TANGGCATNNTCCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGNCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATTCCTGGTGTTNACNTACTAATAATTCCTTACGTTATCGTANGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATNAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGATTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAANTAAATAGNTACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGNTGATACTGAGCACATCAGCAGGACGCACTAACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAANGCTCTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGNGGGGGGTTTTCGTTCAGGACTACAATTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGNAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTTTTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAAT
+
"*$'%$#%!"'&++#)$+$&)*('(+()&#*$*&"'%&!'%*)("'!##(#$$!)*#(%'!'$")$#)&!+'($)%*&%%*#"#(#%*&#)'!#'$)&#))(%$'("+"(+#&$!&"&#$*#)(&#")"(#$#*!($')*+*++$"*$*&('&"''+!+!)(&%)#$*(+)#+#*#*($++"%&"%+$!+$&+)!(&%$($#'")$'($+""*"((!#"*!"'+$$*#!(&"$(%!%*($+%+("#'#+#"*'$**%%(&+&)***&'#&#+"$'$!")!)+*&$'!!''!"(()%!$('$+''%&$$)*+(+(&#+"(&%""&&"$&*%!!*")#(""&#&'&'($))))%)!))$$&$%#(+#*(%&'""#(&%%)(+)+(*)+%"(+&'#()$#%!%%!%%)$'(%#*!!+###%"*)'((+*!($%$*($!*(**!&'($")$$#""""+)!+()++"+&"##+#+##$*(!)*$!(%'%!"("#!$*%*+&&()%"(*#(%$)#$)$%&%)#)#!&+*!&&+%"("#*$%!)$%&+(&)'"$%$"&*$$*!!%&&&*#%#'+$"'$&'$'%*&*&&+'$+#(()#'!''%'!)(*&$++#*&$*%##"'!#$)"$*'"&'%$*)&)*""%%*)+$'"++'))&$!"$$"(+#!)"$)+%"*#%!+%$!'&%%)('$#'*#("'"$#)"''!()%$)%)'$$'$+%#))&$%'*$'"*&*+$"'%&%%)(($*&#$"$+*!+"%&&(()'+*$%&&#&&$)#()&&+&*&&%%("'%)$%(($*)#&&'!((!#%&&'&++'*'!*$(+++'&"+*+")%&))('+&("&'*$#*#&$"(+#+)&)))&))$"!%'"&%)(&$!$$"+$)$)++%&')'*%%(')'%#"(+'()'&*!+)$*$$'$*&%!$+!()%"(')!))'*)$')!%(!($&#)##*$(!("#"*&"!&*!#*&&*$%&*!"$)%*%&*%$&'%%!!#+()*!##)%''))+*()&$)#)$&(##$!#)++(+++&+"'*%!&%+#"'&#'((+$#"!)!+"""$$!)(+)&"!$$"+"!*+*+&$!%'+$"+)"''$*#(('+$'&(*(&#*#&('!$'*!*&'+()&'*(&"(!$"$#'+')#*)!"%%!&'+%+++'""''
@r35
GNCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGA
+
)+"%!%%+("$(''%%*)$##+('$'')+"+%%)!()+*'#"
@r36
GATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCA
+
-!(!&+7?-B8FG4GH47&%-0AF7-)C%FEF'(C*2/BF3BCH:$(7&0;+:<-5E02G;68H5)5B"/4,?9C4,"6;@:C<61H/;5A$@0D+2<3<6(DG2D5D7&B=H%7D%B;'=HB6,9'934@,?)0<H<4*6:C?>?6D:!:F;)9/HH$#,6.A#D:""#2
@r37
CCAACTCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGCCATCANTTTTTTCGTAATAGCGCATCTCTTTCAATCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACG
+
)+($*#*'!"&%$*%#"'!$)!(#%+#&(#)%$#!&+!)!*)$*"($(+'$)%('"&$&+$'&+#')#+$)+!$(+""*'%!&(&)&*&#))&$"***$%(&+!$!$('(!$&*'(&)(&)#+&&)'"+")#+#'($#"!#!#"$!")&%!")'#&!+)")#$#(&&%'$(#')$$&'!%$*"'"**"$$'*)$"&%()(#'*&'!$#!)$*(&*%$(")$+)%!"(
@r38
AACGACCCGATCGCCTACCGGTTCAGCCATACNGGACTCCTCCTGCGATCCCTTCTGATACTCTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGG
+
6(8<F8,3;B5+5*77D.D8&%(>29F-)-B:0D@"?1/@!2872@%%1'9+9A&B$F)GA&E)CD"6FD?FH(CE!*7""%3';85+=@6E+$(5?'7C#76!;/E&9,3;%##$H.6%0=793-15"H-9:12&
@r39
CCCTAACCTTTNTATNGGAAACAATGGATATNACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAANTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCAT
+
66%!4'@*0.BC7',,/#G!")9>=818,3;?>G&&A8"E(<E8C">")>:?DB%-%>4'(.G:B,!>/4/:''3;B@6-5BDD2D2@/4G,F.;7H&E7:8(2+?B%)50CC/:?)>;?,402F=80HFBDD5!,$(.G!C8G/GG$'H6(H=:+!H$E04,3-?,G:'0G.*5&G09CH)9!)C=18%-#A80(+1-A%D;@;)-F).+"C>0(E$F<=@+*?*>,E#-FA0D"+C8%H1D%:AF)+
@r40
ACNAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCCCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAANAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTNAAACCGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGNTTAACGTGAAGTACCGTTATGAGCTGACGNACAGTGTNGGGGTGATGGCTTCNCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGANAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCAC
+
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
@r41
NNCTNCANCGTCNNTTTCCACCTCCACGCCGGATGCAGAGGAGAAACGC
+
#")*#$#$)("'&!'!%+%%##%&)'()##(*"*$'#")'&'(!$')&*
@r42
GTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGATCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTTAGCCACCTGACAGTGTGACCT
+
+#;'+,B?BE<*0+2/'F:8%D%;@+5*G8.F?;D6%=B'57#E#F1FG*9#:?0.%#=9;/+">:2"B76:!5&.,7?+C0:+2<5*EE&F&$GB)>C2=.+FC2@F!?&A011,-23>5<CC,,;)69EGB
@r43
GNCNGGGTTGTACGCTGTCCAGATGTGAAAGGTCACNCTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCTGCTCCTGCTGGCGGANGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGCCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGAAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATNTGACAGGTGCCTCTCACTTTTGGCGTG
+
(&#%)&*+""+()+'""+&%!(%!&('))*##)*(+*#'*$$&(*"*$%"&(')&*%+*&+"'++%!%#)*&+("%'+!"(%%'**%+")((%%""''!(%)#$(%#*$$$!&&#"$!((&'+)"$##+#&))"'$$&)!'(!)!(#((("'(()*)!#&$%#("%%#%)+))#%"'!&%*!&(%&)#%#*+$%*(#+$!#"*!''&!((&*"')&'$*)'++"!+!"!"$%#&*$#&$$&(*$'"()$'*)(!!&#"#*&"#*"#+($%!'!$+!+!%(%$))+!$**$!(")#$"''("$)%(+'#+**($'+)'#"!+#%!$&*(!(%&+'+**$+%#(*+*)#!$'(''')!'&)'(
@r44
GGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGANGTG
+
-)A.'$?)9?*D5-@.(D7D5*F-!+'F$?G*H.%=B@A$
@r45
GGTCNCGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGGAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGNNAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCNAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGT
+
9-7GGFH$H!3-HD#;DA@E*:5E;),(-6:E15*0B30?%DH9689B5;9@C,3<$#0F%),9%<F<H>5,FF38$#!4?32+9*&B17+/"B!A$&2/55@/?>C3!D5-??#5*)CC:'C"H:-2B=:E26AH'30"#@',6G##<.19,19(+B"%F2922.1%!B"#1A8>="D;6G$39BAFD@22',&ABF>+4&4/>1=<+0@H/)52-(=5!($'#/F'=4$+!BH.?CA.&29HGC$@%>F!,93*C"1##9BC&2=%A'&6%</F.(E8;@--)"6@1GB?$@!4)"
@r46
AATTATTACATGCCTTAGCTACAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATTGTTTTGTGCGCAGCCCTTAATGAA
+
B5&&=/<$,5&.1'*.!<>'F4++BB0#8!)C(-FB3(7?HD?*G'A*G;E.89:>?C>H+/3(A/.DH/!;B"<?%6*@F$".%.91'18>6&/4FG(;&5D1#FH4")>A40.'@D':0?61&%HD.8H6$@9E5C(CCH)6E,=873(<<*9''.H$4EA8)&(83@B#C,:$EF$65)=-7>C"/3
@r47
GCGTNNACNANGNTNCTTNCCTNANTTNCNAATCAGCCCAGCATTTCGCGGGCGATATTTTCNCAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTCCATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCNGCACCTG
+
(('$!!(#"*"!("!)((!(')'!#%'!%#$*%)"&)%)+)'"+)!*&)'$$)((#'$$(#)!)#"(++##*"#"+*+$**'((**''((($(#!%'&(*)$&(!"+$(%##+&%""&*&#&!!'$)'*$!$"!#++'!*&#!(%&()(+))++%!((!$)&&"(%#*&*!*"#)#'+$$#!+&(+&!'#!"'&#(***&"%&''#)$%#$"(#
@r48
TAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGTAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGCAGCCATTTATCGATATGGTAAAGAAGTATGGCACTCCATACGTCGGCGGCCCGTTCTGCNCTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGTGGGAATTACACCACGTGGATTGGCA
+
1AB8A?8G*.10E26"C=G#@>.4A!'">('=A-B-@A)$(+32@9+1GC/><#/1#0!?(<A9F3)24&""$7G+46F19*0,.E*-F?>$#=$!7,3,?3';+!'>"-@,!8"C(0>><$"+D$8<1%61%77>!D6@$B-,C>!$)='+-70H//>!>7BF5$''B7=%?;@-7C:%*9C6<:D2-807,9)C+!7>=2;AFF6*A<%3=<-@*?=6,1=7@>2*?6GC,'.$+2-'/65/0#DB?+3///8?=+"'3*:=2EC$;==/E+-G>#.5A$E'07@"?>3C7B;+4&)6>":/#E7D'1A<!C!+7;#/3/51",0#F2,:6A?-D67>A#?1(.H66$";5A.5--@5
@r49
CGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAATTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCATGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCNCCGGGCGTGTCCATATCGAGCAGAATGCCGTNCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAACGCCCGCGTCCGGCTGANCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAG
+
7&)G;4H2C7!1,E>#+).;:%!2&=4=@5'FAC1%;$<-#H0'0FEA-C:+)(!<80)=.8"(613<5@B#'4%)AD/@?<<F"2%C''*)5)EE<G8?/BB.,BFF508.G?FE"@61>B#4(!%@+4E-#69:CH)!,:H'0@2#6+"6;>F8)&B?.5=3&9"A*#$(>C<7*%;$39>2%A)1/<"6,42.F3*DF&(3E0&?7H;6.CH++&>,2DH+F$=E(D$9!"=?(5$9=;+):;6%H-=6+5;F3$",=1/8EE*D<G/066,$D3?='%74.G&%!+:-3)##9@@(F/""@6'DH4/(1,,+%42/CAG5F52+&":*)G*/&%0+58@.C8D#F+;D=<&#?@+2.92/C12?8:,*FF0(G8*6;94F%;-75.=/+/E(<'5F38@:(8-"/,E-AAC1)'F6%25;3G"$E3"%>G6:C:A>%#<;>0&,AC><$0>6'&C60(5%!.A'@7@175B1F>0*.%B*6;>,)18.3
@r50
AACTTCCCNCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGTCTTTCTGTTTCAGGACTCNAAGAGCTTTTNCTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGANCAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTG
+
)*'$$%)&"+(()!()#&#()(+'&+**"'+&'#"')"''!+$%#++*%$$)&$+&$"""'###%!$!**'"!%$+!)(&+#'&)&*&(!$$((##)'*))))+&#$*+'*$"*'!+&'!&)"#*$$+)'"((($'$&+)#%&()&&(*"%"!(%)(+!%%+*+"%*$""%$&+&*(*&*&+'%#%$*'*%&"$('('"&'&'$$#((*"$%''$"$!%(&""%)(%*"'#+((+$'&)##%
@r51
GCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCANGTCTTTNTCTGCTNTGACATGACGTTATTCAGCGCCNGCGGATGATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCNAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCCGACACCTTNACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGA
+
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
@r52
NNCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAANACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATNTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCANGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGNATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATNTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCNCGATGTCCGTCACGACATGNGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGANTTTTTA
+
"!+$&$!#"'+(%"*'*'*"''($#!'('")##($*')*!()&$&%#!)&)'%'')%''&+#(+*)"''($("*&$%&$'##)#$#!!&$%"+!!!"##+'$"$'&()#++)%#%%'+"+)!*&(*"(#(""%'+%)&%$%%#+'#)&%$&&$"#*'"%#)*)%+$&"%*"+(*+$%&'''*)"!*"**#+)$#%$('#$$+&"+'!!#'&!!(&("!!$$&$$%'!*(&+*((#+'*($!&)*+)("$()+''&!)%$+&!('&'+*(++"+'#%()!$$""+#*(##"('+"&"!!+($&'!!)*'&&%#("#)'!)'*#+%+%)(##"""&%$&&))'*!!&*+%$#%+&%&'$%+!*'%"$!!)"%++)(%(!##%#!(&)$&!$&%&%)$)#&$$%'$%%'%*!*&'(!#$'"(!()%'('*"!*(*##$!)%)$'!'&%"#$*(+'
@r53
CGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGNTGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATC
+
.*.:G:D7B+(C:)DA$!H9'7A)*H1<3)*;E5F$6,<?%G;E6H<-F'@C1<'41$2$5E18@?,H+F.337"1#17*!54<,+C7)@598-2EGF($(BA03.;0%7?"-6&5?%6:0>%&#/2(=A*A@@29<;*8F/D"'D<?3.C'37CCA<)A,@EF<;(GCH=F1?0B11<(8(=%75G*$%/>+29EG=,-()@*7AD.4;(2G>8,B6+$!(.'?EC4#F-$2;,?-AB.9$!;?&$+=*5'6(,!5'5C'"67E+!"0,@E!426H0B$506H?'71;C((72F/5)6<>%&+*.!++?"<)","!-"F-#58&H'=8#5(C31+11DCCC<(/1C&#3,?$BC;F;2"?(@F7@$:?G4<*&7?(29.)G-@(6;,GH/(==)*C?BCB7-"A):5BA$D47158B-FC.2H@@*+++4.+0,%*7,>BHEC:<.A:>>6#(B6=-G."'*>!H.CD#%0?2;:0C==G#-59!9>G#($#,:6&=-
@r54
NNACTNANCNATTCAGCTCANAGNCNGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCGCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTNGAGTACNGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAANATTCACAACCGGGGACGCTGAATGATGTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAA
+
'$*"#!&*&!%('&&*)&!)#)*#(#'+(!%%(%*"&"(##)&!)(!+)&!(#!'("$)""'!++&*"'('+!#!##$&%)%(&$*))$)")&"%!!)*#*)%+"!(#%("+&+*'*%(%%"!!#+)+#&!&$('$*&)!"&+"!%$'(+!*'%!$!&'"'!(!%*)%)(!#)!'")$"'%&)$**%"+%($+%+&*("+#')+&$#&!#$!*"''#$+!"!)!$+'+%)%("'*')"+""&+"#'%')&""!!'+!+'")')+%*%'&"$!*%$&%%!+("$#&(""&!+%$#$'&#&#("%"*)+$+&+*!)*+'*&(!'%#'$#*$*!&!!
@r55
ANACTGCCTGACGGAAATCCCCGCTTTCTNTGCAGCCNGCGCCTGTCGGCTCAGCGACTGTNCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTNTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGAT
+
)$($%)')#(+&#&#&)!%"&&'##$*&"+'")+%"!#+#*(&'&+)$$%)")%)!+%*(#!(!#)"&$)&)"%((&$#+!"+*#("""(*&&'+(''&#""$#"(()"(%(#"()+)+%#($)+#*&*$)'!'#%+$)*+##')*%+%+'$(+"%+)$$+'""'($)&((%*%')
@r56
TATAGATGATTAAACCCAATATTACATAACAATCCTCGCACNCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGT
+
#EFA(,C<0+"'C+049A=9-7B"/G,D2934,5@.)7$#A86058#/9'<8/*-<!E/":2!(:$''D6*<)<E,E3H"
@r57
AGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTAAGCGTCCCGGAGTTCGGATTCNCACTGCCACTGATATCCGCATTTTTAGCGGTCTGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAANACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCANTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGNCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGNCNGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATGCAGGTAACCTTCCGCATCATCGNTCGCCCGACCGACGGNCTCNACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGCCTATCCAGTACAGCGCCGTACCAAGATANCGCGTGCTGGTTTCAGCCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCCGCGTGGCGGTTATCTGAAAA
+
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
@r58
TTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATACGGGCAACTCTATCTGCACTGCTCATNAATATACTTCTGGGTTCCTTCCAGTTGTNTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGNCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTNAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTNCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGNAGATAATCGCGGTGACTNTGCTCATACATCAATCNCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTGATGCTCGTACTAACCATAACCANCGCCAGGCAGTGAAGCCCAGATTTTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATATGCTGCAATGCCACAGCGTCCTGACTTTTNGGAGAGAAGTCTTTCAGGC
+
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
@r59
CATCTTTCTNTTGCAACGCCNCGGNNCGNGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATA
+
'"&&"$*)%"*#*&*"%%*%!((*$!(###)()+&(%'!##!$$#+%)!$'"$&&#"+(&$(#!*!!'%%#''+"%)!&()()'((')*!#'"+"#!!"!&)(#"$))*$()()(#*"*#$##'))'#(**&")(**)(+'&*!(##))*((*
@r60
GNTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCG
+
#").CH>*1GF5&=8B?0),(>FD@%5@,1"B@0*)#1!5C
@r61
TGTATAANNAGNANNNGCNACTTGNATANANAGNAANNNGNCNNNNCGNCNNNANNNTGNTNACATTANANNATTACGAGCTCNNNNNNAACCTGNNANGTNTCGNNCNNACGNNCTCGCNCNCNCGNGANNGCTNNCCCNTCGNCCGCNNNNNANNTNGCANNNNTTNNCAGANNATNNGNGNATANTGGNANTNATTACTGTCGTTANTNCGATNNNNNNATTGGATNGTNCCNANNAGNNANGNGANCAANGNNGNNANNNTNATNNNNTNCTNNNNNNNCNATNNNANNNNNNANCNTANGNNNNCNANNCNATNGNNNANTANTTCNGNTGNNTGNANCANNNTTNNAATNNTCTTTGNTTTTTGGGTNNNTATANNANNTNACNTCANACCNNCNNGCTTNNNNNAGNACCCCNCACAAANTNNTANAGTTTTCNNTTCNNANANTNNNCNNTGNNGNNNNTNNTCGNNACAAATNCTTCGNNNTNNNCNCAGGANTNGGAGNANCATNTTGCTNTTTNNGTGNNTNCNANNNNACNNANAGANNGTCTANNCTCNGNGNTNNNGTATNAATANAANNTNCNNNANTTNN
+
!$!#"######!!$##!"#"$!"$!$$##$$"$!!""$$"!##!!!!"#$!"#"#!!$"$"""#!#!"$!#"$#!$$!"#"#!"!"$!"$#$$$$$#$!$$$$#"$"$""#"!#"$!"#$!#"$#!$!##"!$!!#"$$!!#$#"!"#$"#""!#!$!""###!!"$!""#"#!#"$$#$##$###"#$#$!!"##!#!"$##"!####!$$!$$##"$#$$!"$##$##""!!##$##"$#!#$#!#!"#$#"#"!#"#"!!"!!!$!#"!!$#"##!!##!"$"$"!"$#!$"#!"!!!$$!""#"$#!!!""$#$"$##!$!#"#"#$$"!#!!"#$!""""#$""!!#!$"!$"$##$"!""!"#$$$$""!##$$"""!#$#$#"#$###$$""$"!"#$$!#!""$##!$"!##$""#$###!#"#"$$$!!##!"!$#"!""$!"!!!"$!#!!"#!!"##$$#!$##""#!!"!#"$#!#$!!!!"$!!$$###"!""""#$$$$$$$"$$"!#$"$!!#$!"#$#$$#$!!"""$$!"#!$"##!$$$"!#""##"!#"#!""#!#$!#"#"#!#$!!!#"#!#$!"
@r62
CGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCGGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGNACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCANGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAAC
+
4)16$;#&#09-$"/<+");&>=E$*8B)5<88@+8%B.F#=(!B:-6G>;6;?<<?,-@8,G+497/A=#("/BE4*1#A?#<>%)2>6H/"F3/!.0A?7?<:G'+@&/!1BC>.*(-@%H+-+BFED$/&>.$1$5F=;0-E7D=;>(#H&8$2"+,G9&1<AEH;!&/42EE>EA*@G?9FG:CAH3?.1.-=&,@!3">,H2638,BC1<251(>-&E9"71!GG6D61#11$$"!DG4#?*=#->,F.&@13B#6;=>#>@*%3C/5)>:$4*-&+2F9&$9?+2%4A>'7#?(A'#3)"$&<+.8;<A%-C72,*E$<$=6$%/!#,&9B?;?+GG#;G7,8(>.=&&:)*)(9>!(E9=41>D?C,4A/C?H-=B27);-&CF@+&):C(*)/0A>*!%AE+*;8#?;!,;H>&0EF>>&0%6
@r63
TTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAANCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTC
+
18&0G&@G2EB9-?FA"B6BH&E25,60.*46-G2-$B-G!:=2(BA9;'0#"86;CCCD?,3!"<?,D1-;G!"'?F0'(":;'%9(7C,7&$@@?'47F&:0>#)1?,%#!6&7:,-(+#B+=<@()@C)654"'!+<+074/2F6A23DGC"A
@r64
TATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGGTAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTAATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTTCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGNTGACGTCCTGCCACC
+
1$)B/A<-88!30D@3FF49.G-!;B4D:D*5=.,AGCHD!-5C#4A&6!.!8=4.=%>*"$B%1E$.@6(8"H0'H("?&C/5?4G./%!%(/$>AC.3C9-1#%FB!.CB=G"*!F0+**;;F%>0'#:16/>DH)5>;H<==069F)2>.:!3$!!4@AA,<C;;B0)""!>B+1:H4)DH+(HC+2)EB?<$2=(+F*64@3/F)@:.-/4G)GAH6*?"3-)G1=?BC9/H,-(6C8:C-D1$"C-)H+7,13%78)'B96;8$4604DB:<>7=!<(7-0<'3"A@B&DD$'0714<27$&"(67=:*=$-./8A5F2;D#23?/*H!<2C>=/<<0,
@r65
CATGGATACCCCGTGAGTTACCNGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACACGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCTACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGNCCGGCTGGGAGGCGCAAAAGTACCGCACCTNATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCAAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCT
+
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
@r66
TCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCCGATGCNAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCNATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATANCGTATAACCNTTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTNTATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACANCCTG
+
,#*A$8=5!10D<>B=E</!!/0"1,-/+G#1#D#,4#!B(>G-!-:D3HH(>!(C/65>'$HD-%/)B2H*F?3!##/B87*>?;>%'("C,-;?%06-=!=/6D?!"-8:./G5"#9)0%)+81,4)+CE#E9<5%$,*2&H02H8*@/(D*('&7%2""25%.H9:3A2>)1">0>5"DE%13B8E3;(5*">=G7;:5'8GG.$7$%E"A@D%E?.G=GD95E>:366+&&'&$0F!=:#%C7':0E75@%.*#1F,E:+F,+D:>-96D8=*9'+'-"2.+8H-7;-457*GE=;D=AD"0/!9%'D&)H)C=&997'B;&5)'$&:63!,(6+<9A&1@&A3@B0)95'<B&*2%)@!F1F?$8H-=1DD,"8@1*>)"')50"D2B*6/H0:FE<?=+6CCH"'4/00%9/-034;($-'32)/C;8-85')C%-6!!+.0+B-F"$"B$(.6%747**,/'C,>0.+#4,?CB>#&C4FB@%#1$"1H5E5D0E=0.31;,A',E44+C.65>3A:5,'>94DB
@r67
GAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCNGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAACTTTCCTGACNGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGNCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTANATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATNAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGAT
+
:E73(?F6!B#(;1H:<@:+>&%@1)%5)G4:;<)/B96>H!7&A37%6A+CD4+?,@:$'=@AH&-;*G1;@0'"<3C&1;63;0"'.6@1)!+47$)78:+1%<G$&G'3E9>BB*?0BC4<*G*&2#H9%,.*=C("9'(<>>-1=)4<(2/>@&'C97,>"%/'AG=4*2A-)9+#DED&7E"0,$(';B0'5G1C-*&'.9C#BC1.(74<<((21+*5.F.E6642$,#!3#5)'14*CE3:E@#.;!H)<89'5-H0#.F'G)C/46,799#3-G:-*@+<4+:3G&>>/8?D$-/)<4E="H0H&<33*7)*ACE5D@&F+>C.7=!B&'@$!<D=,6E'C/&4&G!"&/?-.9*-4;8?@#>C06+A*1,0-F"A:-%G8'!&(B!@(+F:!6#45+!!?&)11A8>A%0B-D+$2<32"+=>G(:4/12.-EE3G)%247"=3$):2%'H)@7'67="'+$:'8H?F3ED"G'F(@7;';?2;"D<>&$<AA$G&G9/-,4-H1+9-?@E;B>.@?8*G.E$C>7>$=;2D6(,G@0HF=7BF&!>1F=11">=&5DC".(61DC"D0(1H#")-?)+8#)'0():C606#H5'#D;73E:*7>C'$D%A26&A#<(,=,8HBH"*$!&@('-/%<HEC071H#/&A1++'5CHB29G;H
@r68
NNCNGGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTANCTCATNTACTGCGAAAACTTGACNTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAANATTCAGGATAATGTGCAATANGAAGAAANTGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACGAGCATGTCATCGTAATATNTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTCACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATNACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTGTTTCTGCAAAAAAGTGGGGAAGTGACTAATGAAATTATTTCTAACATATATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAA
+
&"#!)+((*"'*')!(!$!"$)#+&'&$+&*%"***$+)&&'")"%''+&$#)%#)!&#'$&**"+"")#'!+"%(!$"*%&*%+'($"*#"+##"%(+!%"&%*&($%$*+&!!!%%#''#")&(%+#$!$+'%&+&&#("$''+*'(*+($*#%**%#"#)+")"&%*%+('#*$))'''"#%"&'*!"+$**#&"!#!()$+''&'!&+#*#*%!%%*(+***"&!#))'$"!+""$$$**&"$#'()")!'#)!&&"**&&"%(&%&$'!")$&*%*!&("#(+)!*'%("%"*&&))"%#"($+&##!(&&)&(')'#)!(!&'("*'(#&$$&'#&('$$##++"*++(&%)!$)+))"(#%+$)+')'%++"*$!%#")+#$+'(%#+'!#%!#+(+'$!(***#&'"!%"%%(#'&+!'*#%&%('&*"!!)+!#%$+$)''%$"!("!#$*!#*%'$))$%*+''*%#&!%&"!+")($)
@r69
TTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATNATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAA
+
(4:F>8@(>>>/H,#@H0.)(GAE'4H5&83(->4)>1%:!?44;9,,9@>%1<%;5:E>.:2<.7<>+'H#7?%G5(9/B2$?6D$7'2C&;4$/2'&-322>,661&>F?#:3C%43H!!?.&$4(C(>#9:$C<*?;B#/D6A>B6)*C%!AF/*@+((=)2A,>2,()A&73HF!$#AE>664F>B20*?.2*:9HEE>A81F"%(7@:81#5B5#)8&)1)+$&.(DH;38,*6!2*C-.$G>"0?1-$&<,/*F,A272<H.31:5+H+$:0>&.@FG:'$!;5A#E2<5GD:42H,?=>5?,&:))H446E.&)8'G2+)D8>)"-G..
@r70
CTGCAGGCAAGGTNAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGNGGTTGCAGAAATTACCGTCACCGCCAGTTAATNCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTNAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATG
+
;0%E?H(.>B<(2!H)D@688H"B&1(C#F$HFA)GEDC%"0(&+HF/*51!=;A19>H;;<2F"93;?C63B';#'9+!6EG*47%/E>05>*$2'GCB*DH6B8885A4"GE&H:;:"5<?4$41F=.1%(,.BHEA9B=?"(2>=$E2A.?B&1&9&B49%17EB<.<"7B@,6G@1'@:
@r71
CTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGNCAGCCGCACCGCTATAACCGCACTCGTNACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACGGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACNTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCANACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCNCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGANCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCC
+
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
@r72
TGGTTGNCGCCAATCGTATCGCATTTATTGACNCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAAGGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGAGCGCTAAAAATGCGGATATCAGTGGCAGTGTGAAAGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTANAGGCGGCGAGCGCGGCTTTTCCGCGCCAGNGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGNCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACAGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACNATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTNCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTCGTTGTCGGCCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGNGNTGGCCGGACCGGTTTTACAAATCAGTAAGCAG
+
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
@r73
GACGGGATTTACGTGCATCCAGTGCATCACGCTTGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCA
+
D11!"7@$D5<;!7A4?2D?H'=G+!BBGDFD39F)$D?AH/!%7>)5;6F")B#,?;%$7'(GB$%BD4H;7&EG'7&96D3:AC
@r74
TAGATGATAATCATTGTCACTTTACGGGTCCTTTCGGGTGANCCGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGTAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGTCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGNACGTCTTCCGAAAGAGCTGGGCTATGANCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGNACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGCGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGNCGNTTATCTC
+
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
@r75
AGAATATGGCGGCGATGCTGACCGGCAGTGAGNAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGNCCATGATGACAGAAATTCTGCTTAAGCNGGCAATGGTGGGGATTGTCGGGATTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCNTTTTGCAA
+
,754F&>6.2C-,59EF..$0&"10?EC:?'&D)/D8++&:*+@(*GA!7(H=F&5>%<"@5;'5->+$-'!<D$.E;:CB!C0%B=884H=H);/'+"(+2!(6>'6ED()*>*-BH.+&,7)-(/."#F1A&/;5-)E&8G&9(.2:)E,'%$E@)>3@+G@'3D7?(<A<6B0'"0/#-%>D6!&H0.B*#;!!:.1*%0:H=/@*6<.
@r76
ACTAATGACTTTTCGCCAACGACATCGACTAATCTTGTGATAGNAAATAAAACAATTGCATGTCCAGAGCTCATNCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGANTTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCGTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGNGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGC
+
3.=#A)H@*12'@'85B?.!&:$@:8;4;/*71;;F>')7'.D&6G0'AD=.1)36@.3:70F0//7"?D15AD-2.A#%/$66A87=)#$C"<?"G:3,-=<!D.21.G599'6)"+5;@H(663#&D@F-<(2/FC>6CC8@@F;3+1F+$>?!>!6E%B=D0%D1:#4(<7%,F-E6@A$<BG<G+%&6)7>=9H;+;:(2=6?AA@.0<=#E99E,9D,1G0,+@GGH.903B.DH.3A0-*HF*=,<#A-.?@5F0+;-G3<"*45($1"7:=.B76@60)#233$(BF+)FB33>/?66(/+=-,1=3B<#"6$GD&#=-8<7,=9>+DH+,?)=F,;?(=.HF%8(G9<?8,)47-;%.:8@.9H,*.!":"G>;3@!>8'7,*9$@>5;E!?6*@!1E@(;+810G!3+0$0H9
@r77
ATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGNTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAANAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTCTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCG
+
?;E><H55G4=>4"8#=1;3)-98CG#?(4==H=0A'4)(FE(#5%/G,%C/H,AAD""F>$H#+8&C!*/&#D6.#,;HH)-8.#2.E1),2!G1*0H2%6A13>E/'G'7256F)>HA+E98#@,89422?2A8*:&/036)+>>0&&65#79#>#&><?4397C?+%::)8!#D!5>+6A2D&F('.)=9#=2(*/H8!7-G>+9C")A'C3GAD%C48'>!CB""25!9F<.>F+",?+9<H>H",##.=1&,*A(/EF/A=B:F+-BD0A"62.??%+?B)126H18</A=.>H+6'3'"%3;C2<.=/#17.,6D$(18
@r78
CATCNGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTTCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGANGCGGGGATAACT
+
***)$#'&'+*)+&&!&"%##%+'!$+(*$$'($&&*!$&#$"'$+$!#*+$*+#!%(('*'%+%"&%$$$#(+*%!"&#('(*+$*')%$$&'&!%+)$)&')&+"$$*!'!!%&#!*#'()'&)'$!&&('#!+"'&%*$$("))!(!)(&(!!+)'"+
@r79
CTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTTTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTCTGTAGTCTGTTTTTTATGCAAAATCTAATTTAAAATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCA
+
>1H!($+H:18C)+.AB*HC'@=,CD.="+EB)?-=8D:*.6#?'4DA.#&3A0-#C&-C!?:G%,893<,9@85):)"G#H<</)1&2D3(38308"9'GEE'+$C>-61<-++1'9!CG@?1DC02/(<5EF@%;8,7)E$E(<3+03@%;'%2H..3)1#/3&C**3215&/<-&,9@',3H?2AE0EH.9GH?EGA"A+AB/2<<1&3H8&+@#1-/FH@>"1,-=<+7&H+=+6*CH,E-3E?*8>-H(4H.A;?HD;4082==';3&)@>DC!E:>B1?*7+,D2BCC?=!4C096)AH1?85FC(FB43:3,CG2>E>B!F5>@8'*!8B/.!AD.)'/9)$D8B!;8A0@!)457?"*%!:A?3G*
@r80
NCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCTCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCNTAGCGAGTTCAGATAAAATAAATCTCGGCGANTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATNTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTNCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCANGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCACTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAANCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGANGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTGTCCAGTTAGCAATACGCTTACTCCCANCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTNCTGGTTTCTTTCCCGTTNATCCAGCAGTTCCAGCACAATCGATGGTGCTACCAATTCNTGGAAAANGTCTGCGTCAAATCCCCAGTCNTCATGCATTGCCTGCTCNGCCGCTTCACGCAGTGCCTGANAGTTAANTTCGCTCACTNCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTNGCACAAGTCCGACAACCCTGAACGACCTGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTNAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGTATCAGTANTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTNGCGAGCCTGCAGGAAGNGGATGGTGCAGCAANCAACAAGAAAACAC
+
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
@r81
GCCTGAACATGAGAAAAAACAGGGTACTCNTACTCACTTCTAAGTGACGGCNGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAANCTATCACCGCANGGGATAAATNTCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTTATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCTTGCAGGCCGAAAGATTTTTTTAACTATAAACNCTGATGGAAGCNTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACNAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACNGAGAAGACAGCGGAAGCTGT
+
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
@r82
NTTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCNATTCTCCTGTGACTCGGAGGTGCATTTATCANCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAACTAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATNGTTTCCACCGTACTCGTG
+
(1"("#?:89'+$!9-@94,*%<5@:#4+D0G&0@#00>G</:?:180A3)0.8?:67##D(5F=7)=-;2.C$D)B)A3$6B8-)>=?.>A,84>4;&B'E),B*'.86>7,38AA:5#="3>!(F(A5?5A#,B#3D19(=#D@2<!5(,+,H"/,11-"3"DB06"(9+,)2*9@?$,-#-$6"##@8F(DC;$H@#',*C@>%/7)>90C<.35+##HH,/8-8#BB$CH$G"/&07E9@$0),<75(25&50."!01&C(H*!>&2(9!
@r83
GACGCCGGGGGCAAGATGCAGAGATTGCCCTGGTACAGGCCGTGCGGTTGGTNTTGCCAAAACAGAGCNGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCA
+
;?4)69CC&$?@H&"869B@48*.C);4%H?)8:#@20.?@-$-5*;24:)+B"-%1%9!A59#2"39($<:18>+#"2@8)>$92+62#2/;@+6H)+B/4511'B
@r84
GGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTNCACACCCTGCTTGCTGAGGTTTGCACCGGTTTGGCTCCGGAAGTTGACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCNTAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCNGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAANTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAANCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTGCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACNGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAAATCTGAAATCAAAAAAAGCCAGACNGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACG
+
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
@r85
TTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGNTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGA
+
*)<D9936%&279#=A(DEH=B3D'7'1(3>H@'41D+F8F$D1G8@CAH"CH'!:%HH)!2/5=(FG?>C(8,-+'5(@?HC6>5?#8F@(-AE=!*(,!/7E.9=1,#A01(=@7$C="@H&BH30F=9HD,C%)>6H&27'!/A3'7-D*0%D4"5">?G0
@r86
TCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTNCGTGGCNAATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGG
+
=4@3H,53<625?/1G>83E$;0*7)HB,@'A'49$G5A)(#C&;9>59"E#.25)=($"H"8G1/E&=A4.F!/689%F2H@"?-A6*2)E38$'7-F9==2?7@#"':/AC6H(2(-D*D4"@AF:>CH=/(2*0<3%DE*>/0'%%DE2HD)C
@r87
TATTTCTNGTGCGTTTCGTTGNAAGGTATTTGCAGTTTTCNCAGATNATGTC
+
*+(++'&'(%$()&*&!&**'*)$*'%*&"()("$+'($""%+!!!"!)#"(
@r88
TCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGC
+
2-),$.<"D4*7HB2*0473E4+6>;26@!57".(8GF9C<CC-;.G;H"9$AD2B
@r89
CGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGA
+
B(?>#(-9FF&F4)1'%.(>8$DG"+C0<?67#9H:@%&$/,>B94;34EC!:G2DBC:="9/B@D+?$:B)8(>;"D0C7:C@#4>=,)#+C.(B5#GF'6*!.+
@r90
TNTNCANNANTGATGTGGTGAAAATCCCGATGNCGGTGCCGCTGACCACGGCGTTTACACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCA
+
*%)!%"%$""#'+#'&!)$+*((!&(#*'*+%""(&&"#%*!%!!*($$$$&(%#!+%()&%+!!(&*!%%*%"$+*)+'##*$'($%$*&+'(&'%)##'(&%)$)+&%!%*$+*+"(#$$(++$%)!%$$*#%))!'+*()'))"(%$&+&&((+$%'*)#*'#))!'"%#+#+(+$+(*$(&*$#)'!$&+"*%$&!'&!*!)"+
@r91
GGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACNGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCTCGACGA
+
+%)"&&)&'$&&%%$!%$!!#'+&**!&"*"'*)&&(%#)&+*!'"(!)+*$"&)"+&((()&+!&*%%!!+)%("(&!!#+)!$'%&"&$#*$*'%"+(
@r92
NCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGA
+
%B;+211!;D.=&(7."%9$<F-8,2"#<A%;,>DG8C&9D>6')!F9H7;&#?G04@==33+-&,24B;47!>8("$,##53(F479H:#?)-1-6'';9#9,%/:722E-:)2C
@r93
AGNGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGT
+
/$'H?!5&'4CB:3-5G9-:/$7AD)H&1)'F:$7AE:$:>2043!D$>='H$19>9':*"-7/:B?#@813F37F8AG<5G)@,8E><#F6&@)4@G9?&+(*>=7-1-02/9'789/2$
@r94
NNGNNGATGNNNGNGNNCNGNGCANAGGGCNNNNAGCGAAGTGNCNGCTCNGAGNTNANNCANNCGGCNNGANNNNGAANTNNN
+
$"!"#$!#"!!##$##!$$!##$"!$""$$!!!!!##$#$!$#!!!$!"#"$!"""!"!""$#"$$#"#!"###$#$!"$!!#"
@r95
TCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCNAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACGTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCNGTTCGCGACGAGTAGATGCAATTATGGTTTCNCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCNATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTT
+
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
@r96
CNAGAGTNGTNNANAGTCGGCGTGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCAAATACCGGAAGCAGAANCGGATCACCAAATGCGTACGGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCNTCGTGAAAGCGGGNGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACNAATCTGATTACTAAACACAGTAGCCTGG
+
%&'!(&)$)*!$$!)&*)%&'"!#%*+#(&+$)!(&'%'(!'*"$''("$#+!!*$!)$"$*($'"($+%'("#*)&!%&#$'%%&++''!!!&&'&"!&()"%"!*&*%'+!(#$#%#*&%#++&!(!!!"&$%++'(!)"$"**&"+*'#%&+!##&$*"$*$")&+%"')$#&)$)(*&+#*('%&$$""'&!'*)!#*#(%$!*)%(#&$"(%"*%"#"&(""'"&$$)+)("%"*$$%!(%!&)!$+'!!)"*++"(""++!%#$&*#*+$)(#'$&&))"$%&"$(&$&*"$'!(#%+"&((
@r97
TCNTNATCGAGNTTAAAGAANCAGCCACCGCCATTANGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCANTTGCTCATGGTTTCCNCGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCANGCATNCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGNCTTTTTTGTTGTCGAATCCNATCNTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGCCATC
+
&(#%#(($)%%!+'"*"$(%*!$'#)%%))$&")+&&&)+#%(#!)*)+(!$#*"+$&')!(%($!%)"&+%)$%&%**")+*#%!+*'%*%#$!(')$!*'$!*()#'(#"%!&!%%$&"$!+$)%"'!!*+&+%##(*!&"("*!%$)"*%(*($$"*(&'+$!'"&#')#!)!%+#'#("$%$#$*"#%+)!"**#*&!+((&&(+"()'$"!($$#&)'!#!'+#**"')*"))'+(#($*'()(%%'*%'&+*'+%"#"#*"$)+&%$%)((!!%(&#))$(+"%$+%!*)'+
@r98
GTNGACCGTGANCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAAC
+
(DD#HB0*C"?D=2A7@<9G1:.03/$2*>AHF#62H"/'(1ECG(+$@<8F<(,.D,-21#=?89&(@B7''"DB2G%67'B#.*"7H:H/4
@r99
GCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCACCACCATTGCCTGCTTAAG
+
-''./D&+@CE?(2-7DHB+6:$<@D8&;&&D5918<67&B32(H&D$<EC7(B+!%GA(1D.*+9*(7+--33DA52/5FCH2G&/5F81:/C.F-(?DE7'G7'65A%5%&##C.BB6*<F:,0/9%H#"5/,@C:$1.&H>H7?G($(A636;D;7+%*(3?92.6@,8>>2"84!@GC.*"BB>&4D,6:7&>$<)G54A-HC<4:#,4$6H@/BEE@A%0738+,/#51<F/6%-(3?%D/F*-?=<,6F=D#<)7?B4,+<2.=.=.+14,>"01;G=..%5+/)!1',
@r100
ATTTCAACCTATCANAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTGCTTTTATTAACACGGTGTTATCGTTTTCTAACACGANGTGAATATTANCTGTGGCNNGATAGTAAATATAATGTGAGACGTNGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCTCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCNNCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTGTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCANATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCNAGATGAAGAGCAAGCGCATGGAGCGACAAAATNAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAANATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATTTATAGAACATAAGGTGTCTCTNGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGTAGCACGATAATAATAGGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTAAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACACTATCGTCCTGTTAGGAGGGAAGAACGCGGGATGTTCATTCTNCATCACTTTTAATTGATGTATATGCTCTCTTNTCTGACGTTAGTCTNCGACGGCAGGCTTCAATGACCCAGGCCGAGAAATT
+
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
@r101
GACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGNGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTT
+
<A91&H/96$19(5=-A&A39--,)'C3+A>@+<=F;E2$C&F?(&:F!@.2B6+94B:<*2C%1C+B;+>!$!8)8.$;(5E?.G51:E5+78$D5G!6/H.&$F.)*H/5?27@:;95='9B&%G(+H3,@FD*96H<D4D-C)2,*B7&'3;C%-G4<D63#A##E&(!-7+G)C,7..
@r102
GCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTC
+
68526F(4./*E5348$+&D"=<(@&1@GH.C<-"@94;-4
@r103
NTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGNGTCNAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCNAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAA
+
$00DFA(,+5=3F-"16!GF9C>:#@C38H*C-H&$?$%0"<$=7#<>)FD$@+H2H;&14+E&7"D<4D,4;--16273-H#!+-1<-&@@<C-:*1@D5:G,*%D27F#"#5@8.7>B;(B"=,BA==#3H9'*F!1?1AGB*((G!*+@B!FC1D04C'A0!&@=?!3$0:A/80,$%G1$B94)>#!+
@r104
GTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTNAAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGNCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTAGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCNGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAANCAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATNTACTCGTCGCGAACCGNTTTCATCCGGCGCAGAGGTATTTTATGCGCGCACGAAAANCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTNTGCAAGACTCNATGAGAAGCAGATAAGCGATAAGTTTGCTCNACATCTTCTCGGGCATANGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCANATAATGATTNTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATNTC
+
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
@r105
GCCGCCAGCGCATAAACNAAGCAAATGCGCCGCCTGAACCACTAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGANCTTATCAGTAAACAGAGAGGTTCGAAGTGNGCGAAATTAACTCTCAGGCACTNCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCNTGAATTGGTAACACTATCGATTGTGCTGNAACTGCTGGATGAACGGGAAAGAAACCAGCAATTCATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACNGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTNCGAAGGTGTNATCTCGGATGGGAGT
+
5FB$.!86==.,$GA'7>9/0-7<"2/3'C49.D*</B6F230?#2#E(*8-9!-@//-;368>D:5)?D<0C/G531,+'G=HCEB&:EDDH:":A&:28#+"';.=63G6)":B#=-1B&D4CE78>8:6??)<).2,$:B7-7/:?$%>H%&6<$EA@7@>A@151?84H-3E9@)'0'-%=::E1!);3G5?771:,&&A6$0++?H?0**1;FG93$<@+A#"$7)/F!A64-52F<E.(#!9$?;%9/$08F>G:9.C=9&8B3F(*:?F(3':#3?/HDB:./GEA:.CH/*&-))FB*7&%.#0;:%:B%;A#?E"65-A,$!-50@(/36EG!:7*4*B<"E"60E'5<A;.27BE6$>)0EG!%A2/CBDC>92F)7*57E63!D@71@@C,:&->&9@(79:;EB97/GB5=GH9#%,%6?18HA7H-93A@3?E2)(G.$C+D;F46/G
@r106
GGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACACGCTCCTTTTATATTATTCCCNTTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATNACAGCGCAACACAGCAATAAAGCGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTNCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGNAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATCGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATTA
+
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
@r107
ANGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTNATGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACT
+
#$=8!.34',,5E,;'$;EAE2;=/0B@+/#9+9:FCA+7!;%'!D;A+<G8)D/087(18-HFC/F@(+'&!7#/C%"H6,E-24#=<CE+2+8571*94(C'>9@+%7.8412"+("-8&A%-H3ED6@C(8,)#2$6B'8<E5GHE;"<1?C&6;G+C'394E2>>'E@*8:$C*4;
@r108
TACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGNGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGNAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTNAAGACGGAAACCAGTTTCTTNTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAG
+
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
@r109
GNTANNAANGTTTCCNAGTGCAATGTTCTGCCTGTTCTGTACTGGGAA
+
*&'"'&)%%*&*"(%#(*%++)##"!+"&*"*&""!(""!)(+#!'&(
@r110
CAGTTAAGCAGTTAATTTTATCACCTCTAAAATANATCAGCATCTAGCATGCANCCTATCAAAANGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCA
+
1"%"82.@H%16FD!8*44<0;$$DG),)%E'G;"'>E0;4@/0?<?&:@<:="4'#=!1,-G&H>==6,5E#!*-3A>*F;<:@9>""6)4">4;!4*A'')6F*$6A!$/#>*$38(
@r111
CCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAAC
+
->'F/2?&;A1<2:?(C8A()H!';8!5.6)BH,6E%'+>(4C
@r112
NATGACGAATAATCTCTTCTTTNTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCNATCCCCCAATTTGAGGGATGTTTGATCCCTCGTGTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAANCATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTNTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTT
+
!"%++!"("!)$)+)$")&)#$'*&+)')(%'*!&'"+'++#++*"'#%+*$"&#%%(#*#&$**)%(!"#*'"!*(!("""*'$$#*$'&$'&#+*"%%%*+++)%'"&$+&&)!'!#$&!(&*(#!"!%$+%*"(+*"!&+""!)!!&')'&#+%+&!+"$))$%&&")%&#!%(%!#"&()#+$%&&)+#'&+!%$&(%!+("%*$+'("'%)!&")"(%&')))%&"!'!%$!)''%)%&!*'*%%*#"*+'&!(&*!+!#*&$&%+)))+((#*$(&#$&+""'"$+&("#%(%)+%*!'(*$)#%"#!!!)(%*##$&%*"$#&!
@r113
GTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTNTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAG
+
H<>$*&"C>>;1?;$.46%H*CD>(.*4#>7%8622G>&A@5#/.,-=6)1)C$;A4?E!6=<D9#.75FH3:63*CF!G7?4;94>F<C'""<%&B3B<2G+5!?)))F-!9B5-77%GE
@r114
GCAGTCCTGCCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCNGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCNACACTCTGGCTGNTGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTTGCTGGTCTGGTTAAACGTCANCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGNAT
+
%G&--GF/+5&2%-5461$/79#CH)!/$HE@1@'##@8+/FG)+HD@A+GC..%,6F&>2HH$H/E"7D0C""C=@4B*6'D%5)."F$$EH3:.-#:7C?C>730,//B74)78+A54)?13,G+16%B-'2!-9?;;*>2E%7(0+0!!:#&!,+F738-!*GG!2-F#F;E1&F8G#"B9A>4869&$FE8C"9@<412"!,-=<B,%)29<?529!E++>?;?)F)>>.=3("2<*4F=*DD&B,@*)H!>"2,HG-3765@D47G033?43H<@2%38C)6-(2;E:9B=)65&<58H6F+>7@)FAE'+!!<#)D2);'3/*<?5G20"3:E!H2G07$%A27:EAD$@1DD9$GAE7#*?$31?+&:4!G0+=4!:6@"4&>=D77=>HE+0>@3D
@r115
CTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCANACGGGCG
+
54:-#0:G4A/=1C1)E8$F@-.@&'E,H(;?D5;HH%G(F58.%D("D+&+8/=@*%A;@$%-&C,*HH7*=/':$">814E!#2FB1DC='$34%9??9E(3(8&$/<"!;-6?/0-51"=<A7*6<@A&.B(>>@C%1B4(A+3?*C(?3CH>046>2H(0C9GE=/'#
@r116
AAGGAAGATATCCTCGCATGGTGGAAGNAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAA
+
*=,;0E1ED,/'DE6!&?.#?;-771B8;+@<.8@552A&&H:-$%<;='2?9B%0A0:*=@CG87:($55;7@4#&F((3(-F2.("&02F$E!+,3'E<G9-971B5-&/;G%1.,9B-4!';+*6B0C6C-&%3%2!+.=C(<4F?35D?=HF1G?$3;+BD0?,?<FFG67)<5F/?@FG@F!2%%:-60?A,;"%3%2G;$>@D<+!@'54=@5#,D#<<<GH,D9.+E%@;-78!);$
@r117
ACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGNTTTGTGTGCCACCCACTACGACCTGCATAACCANTAAGAAGATAGNAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATCCCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAANTANGGAAAACTACAATACGATGCCCCGTTAAGTTC
+
<9(>/F77:(938"672812F'$'/!3:5B44G52<-=$&&'=<7$E?>6="'17/6..1=0BG0'((&9=C8C3<C<3>;H>>6H4#,$)<9A1EEG98()E+3:6;CAH1-!E8GAH@D$@7+9"F:7+&,AD#5#@$7:2FG&@0-D:.-C=6D:+D93("C<3HG&%(CB3;<-G3F>7-1':D,6.2<)1(C6'3H<<>+@+46E)#H%@)>A>1,!*:%A+H<()GG6%=H=6>5'E-(7BF.B86?14BH:?#H+A"EFF'%/>'C/>%:!BDHF2;50!*5=E"38%*9?FC7D)3+871D&=0+HAAH5G)(3(@/&?;EH"/)+%#-(;0EDFB1!5:>!-">:<-&<$+"!>@)=B4DD%':B.GB5H78<=3&EBAA47C;".FFB%:C16+(;1&,=)6?=B:#:/-4'($%6;'5>$"9HH@=)F4!3=>6C)D7)$<1?);9929?@>B!*'$"$A(&)%C%.1F3:F!.'7E(31(A1)?#E
@r118
ATNCGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCNCTTCAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTG
+
CE+&.)#3G2<508B0C;68768+B=.,7.G:)33:/G89F9?5#C'4>BG#+>E2F+?1.G'39@+8+$>E@>3#4-B2F77!%')&A+E#E*-2(!',HB?3=9DG5C6-D02&<<($6H(42'*7A'@:C6,?=>>B6?89B!.6F%!#'/F&A#-6>+H00/4H9,=*;7B!HF:G4">!65H.=?<A(&<G/2@*!&F?9!-1<!/>(%$@=H+2CG)-4+'G%'+CE8D5:;<"3+A<:9CAF;#1/3@-D1&*F9;839-B,,25$;'@9;8'#78%+=09'H%>'%'=&.32E&F#0)EF584;@-,"%$/*C7BAC&:(!093/!)E0H&3G#)3'./.A79*(H@45%?>>0;,(!67F/95+)7.E=FE
@r119
CGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGANTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTNGTCATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGC
+
,5#"B7C8.*;B'.',,*@$2&0//<%2?3694H131%0&/H1,'"#=&@G773F5G/EBD#EH9(2!')504!@%'$.&<A;")9=-'+(,,&%"!3,:D<);-H4%&%$-H179'D;<2#A")/9.'7E;84G2=$9$;7:*6%3B40?+11(*80%6@D*H(A8/+8)D4@7E$,9#&.G3:1=7.$H2G;/3=!A?*2&H&.G<;+G>.C=2735%<AC?<;00,+:D'55AB>&@4==0H.=EF".*9DH+>=6GABF?:B5#@21%*2C8D+2G&5D,*+$;E?4$&01C=3C(82//">!=@5
@r120
CTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGNCGAAGAAGAACGGAAACGCCCTAAAGCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTNCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTT
+
A2->+&,%5+@",6?#?:"+>@A95D1.!A3@H5D)HG-",B;-8&3/GH9&<F+E;:'G/8C6?$FD/+*(563>D5D4-"20(;)>1F="%8E"2@<BH'7F(C03.)2H-=DA"@EF:(/F$G14"):5G9HG>**/!"48,G=F!9-0":<=.A:)>@AF1,;;$=#18,84&><*1A+,)*B89=#C6)*%::+.$942%>*9,%1D/1$03*<G$+A>+,F$)E9:5>.;+#=%AE,***H>.?4?C9;;'0.#1,+9=
@r121
CGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCC
+
9;:D?8D"6&2(67)630$+G8G6F'A+E&B)B)3@15C,2"!=E-,:4'
@r122
GCGGAAGTTGTCATNTCTGGCTTGGACGGGNCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTG
+
.4F$HF2>8*?(40>;4'*%4>9#)%/@'*;(B(.GB6#+4(%@8F?)'(GH1E-$57&$-+%"E0:"#A!;;H?(2@@*5CF%8>#&@1"D%('*&-D8C87F-10/<$5C)E/+1%FF*2=!!D;691->H4:;6-&*/#$6;2B'6"HBD5=2="-"C<FFB@&)G
@r123
TTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCT
+
%3@H-=A+5"#C''DH56890C!B(+9=6"0;A==)+"5D7"E,#928>+2C7,3,0!5551AB'=.!!054<?%7@%&#@*5ECB2291+D53D7+"-=1=2G@#A,*C8=/)>?#(,?E2?D+=73"F2
@r124
TATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCNTAGAACCTTTACCAAAGGTGATGCGGAGAGA
+
"-3=:2=(")7'-6)G'4C!C9??+?E5%)/D)1+>;%FAF<%H%<9(87??4502F>5("7<1B?A-1!$)B2<(A1A2011%/)A8!>'(>>%F:+F%D;&).HC7(A,;,60H=&%1B>*
@r125
TTAACGGCGCAGTTACAGGANACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTAT
+
320@;6,6%D5D*?&*:0B@,%6DDG8,(5$/F&"H2;7E.*##B;;96@9#2!.FE%.FB%.&31,<'!8<;9)@'''00C.(()&).7H%?B@)GD!A69010%..(:1887*A'7<68H0;/+$;"/598@'D27F?#$52>8H.;H9(.B"D'..>*7(9B;')-E,@0'AA/&3A@@E?G21<"#!8*174+BF2,#181=&FB2DF,'##4#
@r126
GNCNNTCGCGACTGCGNTANTGNNNTNCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCC
+
'!#$"%'&()$#($%%&&)"'%"!#!#+)#&)*$#*#'"'%!$'""#"&)$)#&%'%'++"+"%"#''&#'*"&%'*&+"'&'$%'!%!)#+)
@r127
NACGTGGCCAGGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGAGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGNCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTC
+
(A7*'AG+;D&7&'.97CBG6%$;:-*@A9:/>3?:37"E=5+@<?E%@!"(9GC(E.6F00#D+<)#H68CG5;7H&F'8<+C/:3;;-'H*>6?AF@%)/+0,4#/$'3A-+4B)F*07#)?G%BG!.#EA994BA(6(*>F9H56<*)-4!)7:/&7AH#/7#>>?27")D?9=?BB')&!;E',#?+@)38E.$/*/@210+@*)6'5!-'77*A-*AF.5+8?)*5?2G&9
@r128
TNCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGC
+
//CB#E0>!G>?@G0'-+,''!=1+6F"E(G>,"6%3>-FF6%!E3C6:9F<B==/%44G0@,46'."&2-?83EE4%%
@r129
GTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATG
+
@1=@!85H(!-H>#4@@$-4+D>6)DD*C-&=+?F3:0?.,?8;=?1&<-6!!4&7.C(:)H.442#;%G4(F$,C+;?*96C:&D0H@+;AE@$B&+3#HB)>@*?D0,!;&=0B=1E3421':<(*)4F6"-*3+@*$./H8;#'0&),=+<=B=*@"E#.@C@'#&'@
@r130
CCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCG
+
$?.B*$$%-?1F*3#98A%DF,02-G,D3B38&=5$21+5G8(8C/&*'C&"6'04>:3=8'4"*1-'&/90)=-2#B=9H-"+A4;5<A#"9'<"*(<@%9/H9D92B:DD/40@G&>'?#1F&'!
@r131
CAGTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCACAGAAACTCTTTCGTAACAGTTAT
+
*'"@B)!BD?,96B.3*&49!6D=*/A..@%06HH;?78</4*54?<(')'-72#D5(27H.3*+A6".A?0.=E+%<=F/./9=2=+<F2<59/H-)
@r132
GGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGNGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAG
+
3=?<A//!5B<!/'=>5)8378*F33<&?)#<*-'>?-!*E'?E0=CG)!*8(0?%G<*?*AG<&"69%FAD+D?&:/=4+CE(F*=26'!8#/<'(>*=1++E8&.;&3D)-D(.).,H"41+?!)-.7=CED3"$%$5>F<%-A<1#(/@:F=*,-238>H2A@1>5,:7<<F7;D'/-B>7$.$87#5.*G*%?<34(2C097*93%8*>'AHH!*6!CE?/0=+5A*=;/==6$:/+F+2%8G"?>78,>&@$.
@r133
GCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCANTGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAANTATGAAGAATGNTTTTTATGCGACTTANCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGAC
+
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
@r134
GTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTAT
+
+!("%$$!$!&)!%++#+&()((!$)&#*%$)+)**''(*(%&%%+#)&+)&+'#(&!)!#'#)%)!(""*+!'($&!"*)'$)"'&*"'"+#
@r135
NATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACNGCTGGCGGGTTTCCCCTTGATTGTCCAGCTTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACG
+
"<+;(FE%<-/6$GF%>1;-!=%55;8)?@,)8@5/*,>C0%#+)!<:F39;77=.&6D#!$*2*F!GEA71C#%7&E@-*5E4$"?5;05"%E(*@4)B23HG(4E*#'A*78<!7*09"A>7#0;!%#-AAD!:'"C3'!!>>"$&'B"7>C>4(&</,?F@B,"(5%G7$<),3.>0%/F(*>)1,:/HH9*1'&&4;"0)8'1/73";GFC=7$7@*1/6#CG:.($.3C?-4C(6=%<:?0%"%?EDC7/&05$/#6E!AA451F89:B#>H8G=.$2;,B7+@E1B(BE+F;?*#9>'EF6*.3+A:)72>)@$+-50#<*=<27*/B1GC$E9&$/7,44+7HG"25F@1H(#6%3#C"==-HC!:-373<?6D-HG'=<?D?@:1B.=-7"H79#%GA%).%F!-0$<.*?0F7&27GB),A,(F/?!G.!3-C
@r136
GTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCNGACGCGAAGAAATCAGNCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTAACTGATGCAACTGACTCAGCACGCGTCGCCACCACGTCCGCCGGACAGGCTG
+
@5(74/HE13$-@.2>(43*/-#CD2EC/@633/=0G%"6>4;#C?%!;)F>D3%<:)A2;!!B(30),3*5.C'#;3(=F(%=0)E490#6.9*=C/)B?F?)1D=!<<9FDF81'DF$;G;>8;"*.DE8@/9?#G+4)95A2%EB</,H1!0>@'7)&68%ABG;<BE@7&"#,D)',7F;
@r137
ATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGACTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATNTAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGAT
+
$8#;</7#6=*9)0%0FE>!/<9,?"'6#B4G->@")!GG0&!:?6DF=8@)7+2"%+B!&7&?(.G82A5;</B5.@:H"2CC*87'",*B(%)>GE62$!2-953=5,-:HB*CC$C,0$(,8.=4.FAB5:<H>DE/08(3D#/''8A#%8;:-EB>F6;9@A$8/B.2'2;>46D;E<EC:B.3$?.9**C,(B!0B")4:=.6BH53"'
@r138
ATCCGGCATCACCACATTACTGCGNTTATAGGTCCACGTCTTATNCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACG
+
4FC7>2G&/0&34BA-/38#8?-"&<D8,'D11B2,H);'7**/B;F+1=->00B8?87$9#F(67*;%;&=D?"E70"GD;4/FG2=<1HG)/)3%,441.7+(/=.5%DG@04(@?H2;H=+?6;/:8#-3,A3"
@r139
GTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCNGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGNATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGNAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCC
+
C7.$2HC5.ADG4=5.1A<B-1;E<E$#%&1.0)$2#5)'>#:%=1(=()6EB80)@4'>A+98HE8A@/./$61$4,H'$023873(@EH1*F(5;/?$!@BF.,;E7(.'91&C4,:'-D-G32/*;,+7#4D"-7AE:A%*(EG$?D@@6F7#=8!%A?0'=B"B&B*2,+7/<%@)>7(C-(AG!@@?#&GB-%EE#C1,5AE--&34#'=CC3009#3?DD/=.G*917F9(H:"7$"+(@<CC06!><H"!E-:D?6&;?G>'3-GA.;61C=)H<9)F+9CG$?-6&'9=D1,$8*'!6,4'-"=C33-C#B=GC?BF0+?7-6+$>:?AGH9A.!18?1$:#(@2+(G"%<7DB2;*$5@C0&<8)FG/#*A<'('+'89FD$?F@?73+,997$4*4&5%$D9HBB=.6B(/>F';&0(?6EB-DG0<60,F3%,G5.A@/G(?%9:H2/-7EC1-H:32/8;5CH.E
@r140
TATTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGACTGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGC
+
CG.B"/+D78:CD'6).*>944#!2%GD2:AH*103/1=C7EG1D2:5AH9B//C&HD<.D/7:8E0352/!(8'H72-50)!7/199""/5F:<!:>8;8)7D#H-9'&1;EB<&0'0<-7>!=).F/E.;'>H@/+$!("ACHA':,9F7FE-D?C1:=,@)A"2H@!=06A4./3(FHD9>12&/?#B*9BG$&GF,87C0*=?"+AA-B+8#-016.5-)E62>7..:)C?.F8))C/://-&D:HC"86#%!762,7)#%C1?'>>-->)0-4CH:&,8=7FH,,E$-ED<&7$
@r141
CTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCG
+
/)>#'(>,$4H2A-',8.&!:0:6;8(D!/;&;6==0C@8'4H4@:)!$;"?3>F,GE7-/).H6D%$B:511(7$<>B;?B!:D<2/HA:$"
@r142
ATACTGTCATCAGCANTACGTCATCCTCCGTCATGTCCGCCACATCCGGGCAAGCGGGGATAACATCATTCCCGTCCGGGCCAAACCGGACACCTCCGGCAAGCCCTGCCGTTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCNGAGCACGGNGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATANTNCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCNCTGTCTGTNCAGGGGCAGTATTCACCACAAACTCATACATACCAGACNGCCGGTACACCACGTTTCCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCNATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCANCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGNGAGATGNTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGANTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGNCTGCAGCAACGCCGTTCACGGTGATGGTCATANCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACNCCCNCCGGCTGGAGGGCCACGGTCAGCGTCGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTA
+
+!'"'"''%$%"+#("#&!"#+'#*(*%#+%!!!$+$'%#"&*!$(%)'*)!(!!)&')*#*"%$##(+&&!"'(#'&+!''#"&$$$*$&*'")*'%")('%'&()+%)*"!!"$%"'*%#&)"&)"*+!*$)*%)*"%!(#$&&+"""$)'"""+)+$"!))#%"+&)%!("!*!*!'&!$&'(+'(*#&!"#&!+(("##*+"*'%$!$!!*)"#!&*&(%'!&)!#&$&&*'$!+"$()%#&+$!%$(*&)%&&&"!&"'%)$'!%#&&)*&)#+$*!%#*'&*)%*#%"'&"!####)&"()'+"(&$*!)"+!&!)*"%'%'")%+"'"!%&)*$+!$'+*"*'&"*($")%))!+!#+"&(*!)&"#%('%$&(#&)((*$%$"$!)("'*$(*%&&)%$()$$+&"'&*+!+%"#*+)*""&%++!*#*(+$#%#'*%%++#&&###))('"'%(&)$#$$+!'''#%!)*#+##+$'#$&($"!#"%#"+##+&$(*#'&#)"!($!'"")!%('(%(!!%')#++'+(#&'"#)#)!(($+*$!!$%"#)!!+&$*+&+)$&"!(("$'+%'(*)(&#""')")"(*+*!!%##('&###((%((!('!&''!+(!+#'!&#+$!#!&''"'#"$$'(&$+&'$$$'&+%(*&(')((*)%((!!+)$#)!%)&((!(!%%$'(###"'&'$(+)$!!)*)#*#"#+((&'*&*!%**"'+%*&+'#!))(#))+%&"$#$$*+)#!"($*#!))(&''+&!*&(&)#+)!!%$'()"&##$)#""*"%)))&%'(%*%!%)#)%"'*#$(!)$++&+$+!!#'"*"!'*$'#'#&(!"%&+$)%+"$#)*!*((#++'%!)*&(%''**+%&&""'!!&&))"+))#")!$*+"%#&+$$"*($&#%($*#++'#)"%%"$'+!%&$$'#(!)*'#%$!$%)*)#'(*(!!%$*+'*")+%+$"&*))*!%"*!%&(%"*)*(*(+&)))&$"!!#%"'(($&#&)"%'"&&))!+&+)$'*$$*#")+$*$$'"+$(!(+)#%!*%#'#*)%&%%(
@r143
GCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTCCCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGANGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAA
+
H@0=0FC,B>&G573E1D8'<.532E>F8@"'%8'@-31B#>01"G-7*!HE87-@9:0H5<4))1(D5@1(?80H&F-,107)-!$F41:<<4F3-'%-=:(#"<08D"/<1$('$')$?H/GF/481.+62$+>3?F/:CE5+/G2$-G"@>)8G(),*G%
@r144
CCATTCAGGGGAGCGGTTTTGAACCGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGT
+
'B#)D)25.)>E721+26G$4,;G>1?8GF,)99(C@.7%"E;%HA<*;3-#)**75;&?@$*-A>4%F3GG$$EC.6+;03:,B40HF.?=;A@"?;G(!E?8?7.5,/296873+&,C,3?219=<0'7"0:=(*FC"6E4"/H'HF=D5='<
@r145
TGTNTCNNNGGNTCNANNNTNNCNNNNGTNNCANGNNAGNNTNGGTGGNNNNGNTNNNANNATCNNNTCNACNANTNCNNCNNCNTNNNCNNCCNTTGTNTACCNNNNCGGNGNNNNNNCNGNGATNATGGNTGAGCTNCNGNGTNNGNTNCNCGNNACTCGNNTNNANAATGNGNTTNANGCCNGNTTNCTNNNA
+
#!##$!"!"$"!#$!$!!"$$$$##"#$$#!#!"!""#!#$""""!$$!#!$#"#!"!#"!!$#!!!!!""#!$##$#!!""#""!#!$!"!###$#"#"#""$###!$$#$#$#!!#$$"$"$###"!"#!$##!!##!!#!"#"!$#!!!#$$###!"#"!"$#!""$#$""#!"$!$!$""$"###!$"#"!!
@r146
CCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTNACGTTCNTGCAGGACCGACCG
+
'+!*#)'%#&%*$'%)($(#!()&!)*&!(#'&(#)+'$%)"'+(&!#%$'%*'%(+$+#"!#')%"('!#+)+"&$+*"*+*%+%*(*%'%++!"#(+$'$)'"$+"$
@r147
CTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTNATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTGTCAAATCGATCCCGGTA
+
,C96;F?>7$*7G#'07C.96-.8-)6)1>#3@*=AC,'9,,?(*?A*B#A0F$9B;3D)!&<)0<AB11.>?C+-,57>A36<6$$F=A<9:92;$+FG7#H!2$7.<1H,+8>0H&&006,>,/G;A<'2#>&0>9*$H/8E2#G+%%E@7)'5C1C/E%*:3)22>D(3%(+>B&.6=<7$;1+*+#+1$C!0+-:&64H?6&*26?D9!@$C"6-/D/D7>38$*
@r148
NNGACTACNGNNANCNCNTNNNNGGAGGANNAACANAANNTNNCCNTNNNGTCNCNNTNCAANNNCNNCAANGGGNGNCGNNANAANTNGNNGNNNAGNGGGNGNGANTGCNAAGNCNNNAGNGANNATGATGNCCGNANGTNTCTATCAGNNTNNATTANNNNNNNCGNNNGNCNCTNAAANNGGNGGANANNTNNNNCTCNAANGGANNANACTTNNTNNGGNATCCNAANNCNACNNCANNATATNGGTNANNGNGNG
+
""#"!""#!"$!!"$"$#$#"$"##"$!$#$#"$#"!#!!!"!"#!$"$"$##$"!#!!#!$#"!!$!"$!!$$"!$""#!!""$#!#!!""$$$!"!#$##!#$"##!!#!!"$###!$#""#"$!""!"##$"$$#""!!""##"""!$"$$"#!"$#"!#$"!"#$##!$$!#""""!$!"$####$$$!""!$""$""!!#!""$!""$#"#!!#!$#$$!!$##""#""$##$$"#$"$!"!$##"#"##"$$$#$
@r149
CTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCT
+
G1;#"'G!6&899,:H>@(E'%.'"..D--=%9FEG!>262-E
@r150
GCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTNCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCNCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCNCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTG
+
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
@r151
CGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCANAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGAT
+
9;G6#%.C?)"1"*8"1(377+9'2=DD(E=*C&)90F#'<>%%=$G'D'?00&#0<$+3>?CD':F8:CC;&2G*61C7<+#C.C4";@(@6F<FG%.>DB76;D7E#F@,$>H.57/@D>H9E!BB!(9B#'@HA-B"E-+;16)8,
@r152
NNTGCAGTTCACGTCGNNCNCNCGCGCCCATACCGGTTCTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGACGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTCGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCNGCACGNCGATGCCGTTCATGACCTGATAACTTCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCNAAAATTTCCTGATAGTCGTCACCGCGTTTT
+
&!&*''&#'*&$$'*("$$#"%&+)*&#'$'(+#*&!+#"#&#$"%$$")!"+!)*)'&#)$!&!"&(!$*$+#"#&##&($++($(%*("%!#%&"#&&+'('+%#+!""!**#'$)#&$$%*))("+(*!"&+"!(&"(&!#+%!+'#&+&*"#!$$#+#%($)'*(+&%&#'&$+*!+&$!#"%+(&%+"*%'+$#$')!!+!+$)#+'((!$!+&("+)%+%$!##"()$()*+$%$"&!#&("&+$(%&&(%"&+'&&$#)&"%%&'))'&&!'(*+$*&+)$)')*"!(#$"('&$*#*%(%"$!%'"$"$)(*%"##*"%+*###%#$$'+$%$&$)%()!"&'+"'!"#$')#!'#$#'()&$*%#("!#!$!$&%'($%++!+#+'&*+&$&"")))*&!&*%#()"+*!$!!)#!!%$*&(+&$()*+&'*&(*(")#&+%$(&!"#!&!*'')!'*&##$'&&+#+'"+(%#+"#+%(%#!($&''&%))"**)'#+'!&'!"%'*!&*()%"*'"(%)$(!&&$(()"#)*"'"#()()+(*&#(*#+%'(%!&"*#%$+(*#(('"&*!'%+(*&%$!%$++'&$&"(&)"%*)$$*')*+&#((+++%&#!!%$('*+!#*+*
@r153
CGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGNTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGNTGNACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTNTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTA
+
>%CA$+21==B,H%1E!&223@/?D.>2C:!2A9GD?.$,;-=)&.49A6;-@5;302E>H)5/=72%/:>2*E85?%4.BFA'-4;EC?,<:4+&B6%##H*(1*&>#5AH4.499&3B0$C!%:>+H('H2E=B>5":*E9,%.10&)8D<,;78G;H6;A?2EB2@8AB(E7$=87(D3-@=D,3&A-+=4/$>#"!"6(-96'*)=$F5>>6HE#>$+*DF5:7$/""?8'2(79A8@?$@(?9&>/)#!0=()GF=0D-++9A,!7DG*079"=%"*/G6F6//"?$!C<H(&768C/?-,;4H1B1,:$#8;2>H1-20*@*&=C-+F"6#C#=!=:3*HC:=+E(:.,GD41F.C@#'DA,:E&%4H?0,/$941A3:E3
@r154
TAAACATCCCTNACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCNGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGAACTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGT
+
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
@r155
AACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTNGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGNGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGNACTNGTTAAGGCGGGGG
+
;F)B&($D8(-:!@1:82FF6*F5&")#A""%01:@A00<3H95A+48*!>0%.98/D9GC2.,B-6%>1"''H@+B1B9/$>'>C%53*F@2/2F1(A%1&$:+E6"B!?(D&0#)D@BG(%4"%A+*89?1H0?2$(>&D.7075';*15AHA-B'9'*!(8%%(8@(@-":!251-&=3*7@7C/+2&148*5H&7?D.9;):0B=.?90DD+A(')A!0=F1+BAA+F!8**44.)>*<'';-9BE>7695A4<@."01-)7D6A?.$?H6,7A3-64#=H;9=2)44-7C+079#7*+9D#:)F)&G6E9">F&F#$!;.8$*)C<+&3)@1)'7#=7"839;+BC9C9F809#B)47E=;$:8B:?7%!C+1#<;21F>)+><,.D8".80#EDG8(4,--,1'$A5G,+ED"G(<0B*)=469CB19&<6+)7/&-:7#6=B2?'!.H,/+1)0"389%8A,$
@r156
NTNNCCTGATAGTCGTCANCGCGTTTTGNGCACTCTTTCTCGTAGGTACTCAGTCCGGCTNCTATCAGCATCACCGCTTCCTGAACNTCTTTCAGACCATGGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGAGCGCTTTTGAAGGTAACGTCTCCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTTGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGNACGCCCACGANTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACNCCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGANTAGCCGNTATCCGTATCCTGAGCCGTCTGCAGGTTCAGGGAGTCACCCGGCATCAGGTGCNGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGNCGTAATACGCGGCAATT
+
"'%##+&&'++$$+%'&(()''%)")#+((#(&)(%$#&&!("(")&%)&$%$*'%''+)("$!*%$'#+$%*!+#)"#$"%*#"*)""%)*)%''$$%+*(!&$*%!)'!"'%&*+'(!(&'+&*$$+#*)+(%&!'*#)#%(&$#"!$(%+)&#%&)'*)*+#%#!$"&!$"&+)+')($#**")%$%#&("!%++%*(***$()&)&*))''#%")++!#"'*&''(*(+')'#+$!$**("%#*)'#()'&+#&"'#&)+)+)*%*$%*$(+''*%%'(**$$+#!%#%%!!(")*"+*!)**#*(!)&%&*))%#!(%#*$"$%#$"$##%%"&%&)"&"%$)'(&(%"&($%()#&)#+"#)(#&#&&)$%&'!$%(+"*#!%#$"((%"(*(!'$!("&'+!'+*!*(*($')(!)&+%&##)(&*'$!&*$'*)")"(!%!'#'$'$'$!*+$)&$!!$+)%(''!(*"&+)"+!***$""""%*&+%##)$%)*'$'*+"+$#)#""&#*$+(")+")+
@r157
GGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATCGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGGCTGCTCACNGGATGTAATGGTGGCTGACGTTCCCATGTANCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACANGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCC
+
+""*!"!&)'*+$+'+($+((#(%"$')+(+&!''"$*)'+%&+&%'#%'$!$("''+$&&&*"&&*"(*&)'"#)"%"%%()#%)#!++"!!+$!&*%)#"!$#*'"$'&#!+*!&'*)"+")+)(*%')*!)$&*%$!&'(#!*&*"("!*"'%$*""&"$*)"&((!#+%*)##"(%$#$!*%%)(+"!)%"+)"$*'))+#)!+()#"$+#"(#)+!#!#"'++&'#*!&$%$$#""(+&"#+(+!'")&&()!&!%%+!'"$+!"**$!)(&!%$&"*"$"*'!$!()&'!+)+!$&(!$$*&)')!)$$$#!"#!&)"#))!*!(!)&!'$(""+&(")''+)!$%&!!
@r158
CCAGGTGCAGGTGTTGGCCAGCATAATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAAGCTTACGCCGGACCACCGTTCCGCCGACCAG
+
*D=6*1+A,,B'5F$G5&.C1-;1FA+3>",'616A/7+5?%'D6.G.6;+F<%%>,61%7%<0+:8)7@!95$-3@DD,;#3..$929"89%D$6ED(B)>/'4EB2?;)?A(%0+56'0H@8&#=3?7-G;=>>D"7/88EA<?0):<GD#?B8&B!*@G,.&C)3"'+B&<H#!*!59)<'H.B$1'$8-=91/229<4"<2.%).2E40$&7<@!"3D#9$93"+)H"(=
@r159
AAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCC
+
4GD,CH+%E4@7E2AE4CE!E:7+C><?67"2!+2D>'%5@+:.43-C$%B+09'GE;/$;9'59%E')E32D(H2BGC$=4+.!)?D.!@4!C<0%/:E6=74&13E3="+!
@r160
NNTAGTANNNTGTNGGAGNAATANNTNACGGNGTCCNTNNNTNTNNNNTNNNAGAANCANNNANGCANNNCNNGGGCANNCANNNTNCCTNNGNNCGNGANCNNACNTANNNCGGNCGANTTCANATTANNCAGATNCCTCCNATNGNCNNNACNGCNCNATNNATGNNTNNGNTANNATNNNNNNNTANNCANCCCNGCNGNANGACNNNGAANCNTANANTNNGACNCCCANNNNTAGGCANNTTNNTNAAANNGCTGGNNNANNNGANGCGGCNNNNTTNNNGNCTGNNNNANTNNTCAGTNCCANNNTACNCNNCNNNGNNNNGNATCCNGTACTCGCANCNANNNNNNNTNNNCNNNNAGACCGNNNNNNNGANNGNNNNGNNTGTGANNCAGCGCTAAANNCCNACCNNGTNTNACTNNNNGNCNACNGTNANANNANTCANNNANGTTGNTCNNGGCANNCCTNCNAATATNGNNCANGNNNNAATNCNCCGNNCNTNCNNCNGGNNTNGNANNGGGGNNNGNNNCTNAACANACACANANCGTCNGNNNTNCNCCANNNNCT
+
""!$!!#!$"!$$!#""#$#!"#$"#!!##$##"#!##!#!""$#!"$$!"!#$$#!$"#!!!$$$#!"!!!#!#"#$"$$$"##!!"$!"$!""!#"!#!"$##!""!$""$"$!"$$"#!$$$$#$"!!##$#$#"###"##"!""#!#$"!!$#!$!###$$#!#"$!!""$!""$$!""!!!!$!#""$"$#$#!#"#"#!$$$!"$"$$!""!!$$#"#!$!##"##$"$##!#"#$$$!!#!$$!$$$"!#$"###""#!!"$$!$$!$"$"$#$!!""!!$#!""#""!$!$##"$""#$"!!#""!#$!!$"#!$#"#!"$"!$""#!$$!!$$$!$$"!!!$"#"#"!!#!#!!"$#!$#!$$""!"!"$""!##"#$"$$#""$!$""#"#"#!$$$$#!"$$#!##""#""""!$"$!#$!#!"#!"$#!$!"!#$!$!#"$$"#!"!#!#$$!!###!""##!"!$#"#"$#!"$$!$##!##$!!$$"$"$!$"!##!$!$"!#!!!"!!#"""!!$#"##""!!"!!#!$"$#"""!###$"!$!!$#$$"!#$""
@r161
GATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATT
+
/60)?'G!#=*'#*2?:2;GB@74*EE>;)F<<B$47'GD7?,6.?G*#2<+#$628C(5.>&@0"G"7(CCA<#8+-G5816*=6%#?!GB"8?>"6@&&7A>C9472(/"5<;A",:&#B?6)28F%9%#H,0B64CHED=3C
@r162
GTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCNCTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACNGTCAGAGAGATTGA
+
65,6(C#E&C$+<.@1;A=C6$1F+>8&64E8.!=-!%5%B!8-.+";H*<4B@)!0,/;2G23*0#C*1+'3?'FB76)(C6>>:&5(75&B*%)2/>3H#&#AE+D/AD,<-;;%3&!0E0)(/7G&86/+'%7<-'&:90$,G(/1@=C.3;.E4E3.79;C;A3-%FEB(G>+5A1-:=A+&-4H:60(,77;<26?&
@r163
AGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCCGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATNCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAAGCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCNCGTTGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCNCCTGACGGGATGCGNCGAATTTTCGCCGCCC
+
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
@r164
TATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATA
+
>(8+A>%462<6D@H@,:8F$B@.?061C4.,5<5+%/5>:1):+.0C%%;/4(F=0"H:=@B7===*&%C1#)"-"316#?&B?B?:9-.14$&/(%2:')-$8";H%B:A#$AD2#+'AG%-*E=@&B%@1!!><5!0#;CC<=483$*@4"'*)*(*"6)@?/&2H8:39E,DH$@)#(EC
@r165
GCGNNGTGCNNCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCC
+
&*(#"*%%)#%+$!+#(*!)*$%(%"'+*%*'"""#"(+*)$*(+(#$)$($$)"!""#$&(%())*(!'*'(+*))&('$$(%+#''$##$"*##')+"+"%*%"*"+"!&+*#'&)+!")%'#'&)#)'*%!#'!!!($''!+("(!&"#"'$!$(&)'$+#%'
@r166
NCGGTTTCTGCATCAGCACATCATCTTCAGNCTCCTCGNGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATC
+
"")++$)%&#&+*'*(*#)$+!(***$+!*(#('&*&')(+')*%!%*'"%#')((&"$(&(!)!(!(+((%")!$(%&+#)
@r167
CAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGANGACGTCNGGGAGACACNGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATCAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGTGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCNGCGGTTGCGGCAGAAAANAGCCGCATTATGGNGATCCTCAACT
+
)F'"+@@-/"C,&7#"8%-;E4DA&7!:*9=0:-G??G"".,1%3#:#%>/>#'-FEA#H+4;C>:6G!@F:F#6),33,7')))?1>;.F>DD740:HD8/!%+5=34+3&@+5A;!%<01,?,&C9;/(*6<$2E>+E!G!E@A01!?A(0"#2H0;(GCC4E@'&D7!!=E39!@1#;)@14E(2$)#()%F5"+'=2@?:H.(A(!<8%:?AE>/F#11+85/1.,DHAFE'E59087H7$G&&@C!CF+C3+7HA<F!.D39*1EA0<A&$6G%$*"5(C"33;&C*0%/7;<.=</G:A&HF7%B7(46;.A>;;ACF:C"D>>E,D3068$G*C(+4A.53;8?D6!8DB#F66>D*!C4=:0*>/8?-7!0'H@;!8%5'#9%19:2>B>.=+2+74&!GG+29C#<E9(719&91>167-+"9!2(8,!)8D&11!,?;)#>H9CE
@r168
CGGCNGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGNGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCNGCCGCTTTCTGCATCAGCACATCATCTTCAG
+
%#%"%)&+)#*#!''(%&$"#&()#'"&)"*%$&)%*"#''%!'$"*(#((''%((*&+*(#*))+%&&)'*)**'#+!'+%'$$$(#"'!$%&#&(+$#*!+$!+%))%)""('%!*"*#"'!%$(#%%')#($%)$()$!)"#$!&)#!#+!($%%"%(((+()!&#+#!(*'+*)")+(&*('($#'***+%+*)*%%%(+"*'"+"$)+!%'%&''*'!*(*$'))!)%""#%&#()"'""%)""'+#$"($%)$(*&''$$$'$%+!"#%!('!&&*%++$&!#+*$
@r169
AGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACTTCAAAAGGTATA
+
.C<'G!->H/15109;#4D9EEAH5-70)>B)419@E525+"C=9E1F&-?0<,"9!*#*%&<"*3*4:'6#$<'&.G&7@H&-AB'8':?-#$42"%D01+(&3)72@H<8B/?6*%.84G14<*6$981A&3A!%AH$:#1+8($*#>#192:7-#!$FE<!GDHF:E:6E(6>1&+=,)D655E9#B<C,/%65G"@/>$1*">;@</26278;G+#A147;!F$=6+950&FB95-D:E=)&<=7E!D(E7*/(B*&B"@9:%A'/4F72<7AD%!H;(E(&1.CH/5A:9#0,%&0$E4E'C&D%B?D/*@)..DC84-
@r170
NCNANNAGNTNGGNNNGNGACTANNANTNGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGNTTGAATCGCTATGCATCGATCNTTTGCAACGCCACGGGGNCAGCAAAAAATCCATTACCCGTGCGCTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCNCAACGNTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGCTCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCNAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGNGGACGAAAGAAATTTACGCCTTTCGTGATAAGCAGAATGGCATCGTTC
+
"$%$'($'#&$$(!!#("#$!%$!%()"%+$#(!&&(##+%&"()%$'*"&')!$#%&)&'*!))$%'+$)%'+#%%%)#"!"%*%&%'*(!'"'&*('!#'#$(+))$*'")+'&+($)'##+)'#&+!'#'$#*+#))!*&(")()$+$$'(!(%*!+*%*%$*()!$!#)#'+&'')+#))+)'$*!+%!$+&)#"+*+('+'#'#"%$&)$)+$!#*%&))%**%+#"(+$$'+($'"!&&*"+($*'!"$"!"%'*'!%#+$!)()'$#(&)''+&$()"())!"*"#)""++'+'#"')"(%))+)#+*&#*'()'+)!#()&"#+$+&&!($!+"*")#$%!+%*")$"&&$%#%!+!'()!$%)$(*%*#&+)'%"#""!*&!$()'(+!")#(*($&+&''*'"")+#*'$+!+)'(%'*(%%((!&%)))%&*$'"'+$!#*+"%(%&#%'&"$("%&$&%)#!"*+$+!+*$+(+"')#$(
@r171
GAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATTTNACGCACACGGGCGATTCAGCGC
+
.?%,"<*F41+65H=83;/+4$%>F6(;4&=$E=,+?&%H%H6'#;E5=/C13B;H!&7(5F'A+/2&=@75@+D&%8/&3C,#7%9%3F>-+H&&,+G0:*A(+4H9FH<=%C:'='?H920$:83.%)G4E895<'HF=&.4H=BB<>AH
@r172
NACGGAACTGCTGGAAACGCAGACCGTGGATTTCATCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACTCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAA
+
$(#'+%(&#%!&'%(**$%"'&%!#$)#)#()&!)$(!$#+"!*((%(#$&(*#!('"*'"##()$&)$""$*&(*(!)"'#"$#)"""*(!(&!!%&*)%'"!%($)('***&%#%$%!)+!*$$('()$'#"%%(!(%)%##"!+!*%#'*$"!')*+)')+&**"+*%+'"($&'('('"(#!''')#!!'"+"#($"'#*'$$$&!*"%'!$%%!$'
@r173
TGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCC
+
G1--:?=0=<)@$1$E@+DA<G/3)E82F7C$72:1;B0;A)2'="3=,44.:,H9.3)=3',3,G?5.)81@@:DFF8=BC%9!&?2'<H/%@!C<+=/6,*+E'$H1F?9520&*+3
@r174
GCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAAACACCAACCCAGAAAACAATGAATATT
+
C,"A++:+8A"=H5>29>?%.F,H.<?>!B@,B?273B3%(@/'+3(A"?E?B"<5)4.!,"6F'>:D>E:61$"'9F7&F<@*@>/$
@r175
AGGTCACACTGTAAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGACATNACG
+
1%G+D0('915.+'G1/697#$FH72&@"8A7"9+A0:A54GG/1+52#3(F03('*8!1;2,A
@r176
GACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATNGTTTGTTGTTATAT
+
A+B3.C@:0+#:%FG8*4",(:C%FF'?7!'G&;:&/=*(+.0.EA4?5-:-D*9H6(.'99&29853%8C"E38.>B(+=.;C>=>)/""+@?'"#5?F7*2&;EE>H-?.=.+03BD,611A#B:1"=.$+$2A5B*D(!@:B&'%ED>FB&936)&3+"B?EE*+8/<55C!2&F.,='86A"BCDD
@r177
GCGNNANCTTCGCATGCGGGNAGGCCGAAAGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAANAGTCGAGCTGACGGAGGATAACGCCAGCAGACTG
+
#%%$#)%#)!"&'&*#"%$&&*%&**%($"+'!()#')$&!+)#%"'##&!$+!')+&!"''!!#!%*$!#+%'#()%'&*+*!"#*('')+)+*!+%)'"$%%*"+"$'*$)#*$#)))**&&*!(*'#++!$*(!&+!'"))+'*"&$+$
@r178
CGACAATGAATCCTGTACATGCGGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATNGATGGATGAATGCCGCCCC
+
!+$(%++&!+*%#!$&!$*))"#"$#(*%($&*%#)++*%$&(*+##*!+)$'$($#!)!%!!$+(+)&%!#&*%"%($&&')+)++$
@r179
GNTTTTGACGGTGTTTTCAGCGTTACCCGCAGCGNTAACGGTGATG
+
$!1$2'=,*2FFC7G:6G-C%>DCC>:#G7#$40@9402&EE6E2<
@r180
GACCGGGCAGGGGCAGAAATCTGCCGGAGGTACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGATTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGNACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCAGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGT
+
,2A.A02%3;6"GA/,C8!-'&A<!/3*=3?''C1#3$5-&?-CE&>>)G5>4*>79-!"*3C8(4#;=65=B+@7,F*7?E(5<B$F&#G$.AHFH@DE,"6<@C(<+.:18=:A;6C"B6*B0G$&?C(4DD7G+D'355A9B=4,11(3,83+0)#4C/0."4GH<7:C1G/*0?HFB)%!*7E4";.%/5H.-D5(%G6F5#4.D%#EFF@?6/3,C:G'$D#).6"#D897%3'D5!#2-1!&/9F%)%(?>%"C'<@*$"F?&B9H"?>?#.$&,,0@.D4440;>3))$$=6&(1?>9>*(B%*6@,AB,9)?9!*@$=6<84B"?@-4B>&E5-H/?7=9D68F==52//DFF/%C=786<$6,CF10+,+E5*(&??+!C@",',=HH2'-5,(=F*+=%6)1$G%5D&D2EB::G<4H2C)%!2;D+1C.*>.6=".@"79#0.195.?+B,3+0(=C"<$'2!=-5??F+'4"4?2+*D<%0
@r181
TAACAGGCGCTGGGCATCAGCGTGGTCTNAGTGTGTTACAGAGGTTCGTCCGGGAACNGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGNCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTTGTTGTCGGGCGGAGATACNGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCT
+
!HHGA<G("7==E(/E2)?2,A,!;7##*B$@@<;@0%A&&#8):1,11"CH*.C,F*D+(542F(=**,B=&C=;A,609)$G),":"2>A!3)--,GG6A2&A<9:92/6/<>*1@2#2G*3F#:#G6!2A2EF.B=3;#+1?#=E<>'->+575&3C-!F1B6-0G=B*-56F0!D-<*6!E2$H)$>(>>5CC8#'G@?&C;#730,5=DA+&CB-*")//58B-3!826=HF6!#9/G$#53+1!958:F;H8/;>=H#CB$G5:@>%/9*EA.+6!A).91=;=7B)6=)>,&=+=*(?8<0#)32
@r182
GCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCNCGGAGTTCGCATTCACACTGCCACTNATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGANTATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAGTAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACNGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCT
+
G6=0AA3?!@9>4?%17>2>9$0D;AA#CH2A#"/)E7"$>>.)./ACD1D5;5-#547CF+&)+5*/G6HEG:#+E?$!,B95'$E%;48+%A2'$&!1H"(49)/9DH&.G&"D,:6(A;>>(2@>/A9E<'8:G2>+'FE?/5$7DA("4?#751)5*H0069;-1.B9D+89G&)4!8-$#5!9A"1@?>3G/H16@0D'2=A,,@$B*$B<=+C&)54D@H3'F*DD0"C1.B;./:=3)(A702G$1CF$4#8+(15*.9;?%!+*!D%0#,H2,181$%/4./;?3A<%H9!1!%)=D/30%!"C3G7G.6/:9/>=.)+4542'C+45-&BE1$E+.8+(8&$G):E?/;,@4."2001E<)0B5%?$@!69+)'"-3*+6&>:=7(#&>";?G(8$7C*29$H"*"AH'((>$0EH.#(7,*6:=.-@2(<7-:.H9C)G)%A=99)+;++@&@54+B$!6$'F%79$HD*)#(9&16=8AG
@r183
NNNNAGCGAGGCAAAGGCTACTCTTATTTCATNTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAANCATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGNAAGACGATGGGTCNCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAATATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACNTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCCTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGNCAGCTATGATCCATATAATATTNAGATAAAGACAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTNCACTGCATGTTATGCCGCGTTCGGCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATNTCGNTTTGCNATTCANCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACC
+
")%'(+&#)&$"!""&&+$+('*!'&)$'"+$+)(!+!+$'&)%**'"+'%!&&)&$**"!&)%"&*&*))"+)"!%!#*#($"$&)!)%&!#%!%+!"$+&#&$'(*#("##+'(+*#'*+"+#$'+%($!*%$+"!$(*)#%+()##(!"%*#"#"(&!'"$'()*%+%&*%""#+*!)!%"$*&&!%+*))($+"!)+*(%!#"#)$$#*"%(#&)()'&#!#*"!'&)+'**+$$+&+#("+"&($%"(#*"(%))'$%!+++!%#(&)#&$))!*"$+*#!"$&$$"!$#+#)'+#%&+!$$'$)#"*'"*)(+*($)%%(%&"$'!##%(&!%$%!"!)!%'!"#+!+%&%)$$*&#%#(#(+$!)+"%'!('%*(&*")"&$)(*(#+(%&(#"*(*%&!&)&!"&#)(%#'!+'*+++$*'%*)%('$!##("#*"$)'!$#&%&")#"!"!"*#+)")'"+%!$)#!+'(*%#)!$)!'$$%*#)$+('"$#)''%!("'"&"%)'$(+$*$(+$&(*(%&'++#*((*)$"$%$&&!!!'#(&%#)&"%+)"+(&%")&(%'#*%%!'$*'$*)$&&%#"$*+*&!(#"*+"*('*()**"*'!'')&&(+&($*#&(&"&"($!*)&(&$""#!$*'')**#'(*'#$+%**#''!&%"'!!"**'"!&+'#&*'!''#%*'$)$*+'!$%$$#%(#&!&&)++*%+$*"*%)"!""%!$%!"!&%&*&+)(&#'&#&$&*%!+#&%%+!+)!*$$"&"(%($%"!$(()'$+"(#*#&$*&*!&&$%$('+$%)##!(!)"&#""*%!$*'%'#()&+!#
@r184
GCACATCAGCAGGACGNACTGACCACCATGAAGGTGACGCTC
+
)(+%$#!)%**)+*&'))%(#$+++!!(*$*"(&''(''"$#
@r185
TCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTNCATATTTAGAAATGAGGCTNATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACNACCAATAAATGCTGAAATGAGTTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCNAATATAAAAGTATTGTGTACCTTTTGCNGGGTC
+
D1%&#"=:/.D+'7DFG>3280(;0$(,'#'/F=9D0!!8CEH94;'$9F291>!9529%657;)9H."8?;09:&6!"8A5;%$+.:61&@D1H0!?,74!'*F;)<-=7H1"07/$$>;53'6=A?+'A&/B<*,A24<3'0C)78AF=&F6:(!H#3(>:$#79?9EH!5F-&35$%&2-49H->/-?'6C=60"=!5>')4BA<=F#"94B01!E!2':1GF5:0:(:A@H?=+$&G0D$#>#@6;?#G>C4+"72G4=-D516=:*#/C,'9,<F=<6':+=
@r186
NGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGNAATCNAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATNGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTAACTGATGCAATNTGCN
+
$80>:81B=/<3#99EA@2*ED5*7('7)0-(;GD5A";'&=++/>A:!$5*5'$F0@9D"H49=36/)#@4,D)@4H)-"*+,#AE62'-"E-@)E8-?=1H<@9D3%C3@+#(D+?$B70'FE&";7-;)A<;<8H7'B::7>(79*;<.4+8EA&9;H,:*H6D".6*E@20,;!CH)55#;A"'9E,H?!)%(D)H'18*80;48,?H(9+7*'DG79>F*;<+(9A49&51*2H<5(29D,@6G1&'2'#.-<2)H7,=G73-+86?G=5+CH?>&=15,+$/!'92"DG3A1=-<37DGF#&C),=<4>*+$5;:E-7646+=!/<01=5=.32/:&;"=60"8".=,76=%0!25$#+$<H6H17/(CF+,<6.:*3-FB$B6%>'3@2=,>+*$.'+15DH?8(";,F.G307%G8+=E$C5<)CG4'(5%58C(2.)<2',2;?;-GFAA*2<5"B;(4'HDH(6(:5G=2%.((C;H#;;58!4:,8
@r187
GCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCACAAATCGCTGAGCACATCCCACGCCNTACGCTGTGTGGTCAGGT
+
:F1/%3-23H;H##3=*.EA<6E@3G97/G:+**2A1!B3@*-D#1=$@"F@).A6>#<$+?7EH#5(15B5."DA!5?>+&+/<'E
@r188
GNCGCCNTNGATAAAACATGGGATGACGACTTANTGCCGCTCTGTTNCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACAAAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTT
+
'%**'#!"%*&+#!#(&(("(#&()&!$$%*'*+)$$()+$'#+!%*)++$"#"%%("'&)'(%$'+('&"'#!+$%(+&!$'*'%)+'&$*"**'(#"*$+%%%&'*$"#*(**(""*$)%!##'""$)"'#'%%++!$"+#&+"!&"$#!%)%(+*%*+!(*&&$*%"+((#!!+($'%)$$$("#(+'(#"+')$'*(("'&&*&!&!("$+#'**#&##)!(&"'$)#('!"%''$%($***+)!!+*"#'&&+
@r189
GACGGATGAAGCAACGCGGTTAATGGCCNTTGCGGCGGCACCAGGCACCGCCGTTNTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGNAGGCGGTACGCNCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAANACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACNCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGNCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAAC
+
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
@r190
TNTTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGNAGGTGCGCCGATCCNGNGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTNTGCTTCCTGATATGCGAGGCTGGACAANCCAGGGGAAACCCCCCAGCNGTCGTGCTGTATTNTCTCAGGAACANGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGANTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGGAAACAGCAGTCNGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGATTCAAC
+
'$"%+$%))!!$)('+$')#*+%))&%$$%%##")$)(!(%$#+($!&"$"&&$(($(#("$$$('$)#+*')+$!)&&%%"$*&+#+$'##%("(#$$'&'))(%*%'"%+"*)!&##&%))&("('&+"#")')#"#!#!+%#))"#!"$$+#(*&(%$((($(%($)'%)$$+#("&)'#"$*#+#''("%(++(*#$#"((!!"(&*$$%##)*$")'&"$$#*#+%!*!)($&%""*"#'&&+%+&+++)&&$$'"*%!'!($!**!%'#"#$('&"$+$+('%*!+"(%#&!&&'""!%$'$!+)'$)+)$)(#!!'"#%')&(*&!#!&('&*%''+%$%&''%!+'*#(!"+)+*"#%()$%"(*&$$%#&)&"'"##)#'$%$&*+(&!(+""))&'$%+"!))+%%$%"'''("&#&'+$!")!*')$'"*+*)&(#!$&"'"(!%'"!'#+&$"!#'##%(+'(++%$$"!!(%
@r191
GNGNATACNNAACTATNNGGAGGCTCACGNACGCGAAGAACAGGCANGCG
+
($&$&)"$")*$%%#&%"+)%%%$*"*$'(((+!$&%+)'$"%$&'!'!!
@r192
CACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTAACGCAGCAGAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTNATTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACTGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGNCACCATTGGTTTTGCCAGAACTGTNTTCGGGCCGACCACATCCGNTCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAG
+
'(+#%!())#'!$+#%&!+"+!(!'#++'!('$"''$*(+!(*'"&%(%%+)")(%!&"*+*"##$%(#'"$#%()%#!*#**"%!%%'&###!%%*()(+(#&&#&'#'"#"%(+%((&(*+"$+&("+$$$!')*%*#+")"$(**$*""*"'!*&$&$"#!)"'$#*$)())%%#&&""&!(("*+%+"'(&''($'#!$'('*$+"&&%+!))#("$(*"'(!%'!"$)%&(&'&*'#(%)!$#!+#'#%!&))!$#)"#"&$!$#&"(%)#%")"(("%%##!")'))!"%#+%("+#'"(&")###%&)"'%'%#*'!'!&#%$"(*)+)%%&#+##$(&&#+$+)*!&)!$"+#(!!#&!)&*%"$+(($%$&!$$'()!%'!#+"*$""+(*$+')"'!(+"#)"#%&"&
@r193
TGCGAGTATATTGTAAAGCTGAGTATTGGTTTATGTGGCGATTATTATCTTCNGGAGAATAATGGAAGTTCTNTGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTNAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATA
+
:?7E>:4<A>;,>(5?.5EE%!(D0)=60H?+B28A&;=62(4%FA*E&1?*F#0(3&:H(;;//(/670'1(7=C:62<:!$?E8B(@4!4+8";?"12814,>!%!G2;*@70#D%=@1AFC$<<H'E3=$$>!F>F!4/749?/D5:?.!.A&@?9@#@1B=D:EB40,
@r194
CCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCGCTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTNACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTNATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTTTGTAATCACGATA
+
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
@r195
ACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTNACGACGCCTNCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAATCTGTCGGATCACCGGAAAGGACCCGTAAANTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACG
+
:**(0%/4D<)A75<68/%G*1/9*F-#""0(:H096.)';4@"4BF*4?9<H;G0$#>H09>%*0)5GD0:G%<1&H:2H5FA##)G>7@=(-):>)CCC#GC<&,:=D<0C16>B(<:%H/%<.D%?D;=46<EH6;49?#::3:F!E:+=4F=H>#@C,D,$8",-&G-&1>7"E2DA5"/(:-?+$8H5G9(2D6?41>/C60!@<53H"6*;A750/CD(.A70;(%9->8'("@E0E%"B5'7+F$6)0$G$6
@r196
GGAGCAATGTCGCTCGTAACTAAACAGGAGNCGNCTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGA
+
?CAC$=61E(F,@=!=&,?56AF1"#2=0%F72CC=,(%E9CGGF=*<+<!8(.3D5@&4'DC<?2"711/G5-CG=$",<!C:8H=1&C.&D66?
@r197
CCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACGATGAGTGGNAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTANCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCA
+
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
@r198
ACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACTTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACA
+
C:(3/=#=E0/5H5"%$680GA-F$5B?=&!D1&-(139A=G/'@'?(F/>1>5#,84A4B&A7EH8G;/EF<>3<%&3GD94&H;'24*'E'8=8/%(-@14H4%8</5!0*!C7"91(0H+C;:D$>A!?..829'FCC7G!*(:")#$:"2"))5+)05G-9;/'#7A002<85<B='H)63$G9AD:FH(2CD4@36'*&!.!&)
@r199
CCGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAGCACAGGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGNAGAGGAATCAAGCAGAAG
+
)#&'+!+&""*"!%+*#&$+'%!($!(!&&!+*"+*+'$&$$)++&#)'!&%")!%$"(")'&)$$'!$"&&$$)%#"*&(!%+("!!("+*+*!&%(*#(#"'($'("%(!!!(+*+')+!'"""'+%((*)()")('*+$(!!$#&)"('%$*%'$*))&'*()
@r200
NATGTNACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGC
+
#($'*++&&&(&($#(%(((($&+"'"#*)&#%&!'$'$)"##(##$)'*)"*"("%!#&+"!+%+&('("'")#$#%%"'+$&"&'"&"*$!$(+++'"&&"(!()*%'"
@r201
NTACAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTC
+
&&#+'*"$(!"#()()#%%!+$**##&)#$#)$%(')*##!($)+'+'!"'#)(%%%+*'(%!&++&&%&"$!'$"!!')(*&("+)*%!##*+)'#%%%**)''''()+%)$**''"$'$+#
@r202
AACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGNATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGNGAGTATTACGAAGGTGTTATCTCGGATCGGAGTAAGCGTATTGCTAACTGGAAAGCANCGAAGTCCG
+
F6!F@E4E)E./9!:9D.=!1@7*E7C<@?5;#D!A04C"H7'+<'!>97CA!$@;HC'H/#')139C&)26?<:8H3D)')<$"887502@<9@*1?*0=9#(:83870!"9BC?9;=9276"H;H6#4)B5&A3B&;F7#.FB)CD4>+(=#C>'0,=D,=6F("4)&0,7-H92)?,/6<1.F;4+;,A,",9G"!AA@>8$E22F'4)?4&48&F&8A6@3.)22.2DFB"76.+*4C3*$9.;CBBB"3B,H/3*D+:$H!+!$3*>2*C,&@%*<6;%(,0*<!+-$(64;!%+HB9A9.G8B2&71C528E19-79-H)02+!B5##"56*3F935A
@r203
NATGACATGGCCCGCAAGGGTGCCCGTGATGAAAGTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGNAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCNTGCCGGGCTGAATGCNANCCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTG
+
&&F!AE<4++?!E--%6,E)),>+4(H,F%!A?(*H/4F.@;G8+2$(=D#?!"3??6$6-)51D.:"0D<=%>+:.4<;928)C75()9?!:@E(;33!$-"=91A0B6+%50:E>1201$(F&2(:9CFH<"5)'4'$>D33*0:.!4=23?#;2@G:)!6@"31+911;>&GA+B-+<C=21#%:51,!C%7>0,E!&&F8H4A(A-!HC&;F9-$='D.%$'<5EB8#?<G12
@r204
ATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACNTGGTACAGCAA
+
=$4G:/CG(,<E2EH4!(3$:<"<)6/60()?GFF$0:75#'8&-A?6>07:H=,H6"7+.BE:G.F",&%#3H0/H9(G#(%6$5"H<<CD#9?86$H@7)@$;3%D0$$9*=>E)&%(9.0&;<,8D&061
@r205
TGATATTGCTTATGAAGNCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTNTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCAGTGGGCTTTTTTGTGGGGTGAATATGGNAGTAAAGATTTCAGGAGNCCT
+
?..*5G!.$3*46?'1/,BF6#>+$-81E;B+(8!6'/=C+30+/@;7>++&7@@&)06>%<DH@#$$7.+-+$6@3$-!4@*C,HF5'D$C<6G$,6/'/G-*$,::4F;D7$A8/2D7G6.,#79GF""B(*3:D6%16E1$/EEG)))<"'GB..'H"#8@-,(;E
@r206
GNTTNNCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATNCANCGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTNTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAANTCAACATGTCGGTTTTCCAGTTCCGGAAAACGCTGCTGCACCGACAGCGGGAGCCCGTCGAG
+
($$'!"!)+$&"&#)"*%(*!"#%+)"!)!+$($("+((&**+&&&()&($#**!!#)!$&*##&&)%&'*%')$%!(#(%!#"'&)($%%'!$$##)*#*("+'%+"'**'(#)!'&+**&*!#+#)#!'%()&###(($#$*&!*%!+''+**#(+)%#(+$'$!#())%!+('(+"'++###())(!')&#$&)+)$%"%(!"&&+'&!&&')(%&%#'$!(+!!%"!%+#+*%*#')&+(*&("&*#$''')%"**&"()$'%&((*"!+$!+*&#(+!)'+")()+$$'
@r207
AGTAAAGATTTCAGGAGTCCTGAAAGACGGCNCAGGAAAACCGGTACAGCACTGCACCATTCAGCTGNAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACCGTGGGCTCAGAGAANCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGANTCACAAACGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGNTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCNGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGNGGCGGCCACCAGTGCCGGTGCGGNGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGTCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAANATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCNTCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGACGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAANGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAAC
+
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
@r208
CGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTGGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCANCCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGT
+
C+"762*"-5#)>=?7,HE;.3%&.1485?,H2D>=6'%<EFG<;?=EHE10>?@AA@A-D=1H.D%@<:.%+&C1B9@$5*8F=A5A$!5<C48+=FE/HGC,.27%&?(D,7:G<1B5$21:?F'1E<27C6"&&#8;-(?-<1+%0<439#14;$6231>&2;/B!87%:%H3$2&")!56GGA8*1:+?G@2,!>>#"%A>86<"%72'""*$";$%*:7)+,?013)CE%)&FC.C4DD,0.F**3=1A43"26@<3?-.0:9&>)7-53DE0+GB'A=2@9>52C-67$>;;F4-:BD!,,6/5)GF'<>;&7
@r209
TTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGNCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATNTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGTGCATAAGGCTGACAGCCTGATTGCAANATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGTTATATGAGCANAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATTATCGTCTGCCTG
+
#1)(!:HEG*H?H7%<6/#67/5%+(?E4$,34G@:'7A4.=+7-.,1&AD;HD9D4,=E12G58F&G(F32?H>)6<72;&47>:",G''@63H'7EA01FGB75CH2!:$"@$G8'-0>GD!;&<6)B+CBG%-*-<1<ACC$.?A,22"8(+(,A?<4:9/D*!2A+6?;8/$#295<)0<6/&E/D.-48>F0*&*9*<>?+,DG=.+7,4>#CF,2#'G=($;?>:(.?8DF:!D'7(*0;./-76*2#.+?7((3070D=HF5.8HD<1%)9;#<73+G#+8*7B%,'D+51AB2D$E-4D&,<5:2DBB*1C505
@r210
AAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTANCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGTCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAANAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGG
+
B%G40?0!9;(*./,,?3&$9)*14%C!4:%59*(;='41+C&.C4/<E424@.B@1*E29B9%7%+F'$%'07:*&/<@G4+9$590!3'.EA%G=H3G1-D*0%E!8;AGC337F==(F&(3$03?&6B>+&$/'A1+D%A3>)-+-'2%+)88=@AB@E7.+-F;0&/F)E)=&5:##;-1)*(333363--%%.#6;-@30??>?@?,3")>-#C;+"-.299)#:B3;837((;-#1(,=-!51.?*D,35"D-=(5&7.<&53%E!$D%+A'5#.<=#?+=/HCCF76>BF-<'8>="+.7=7G3B,D)#&5G'<#?0*
@r211
TTTATATCTGCANAACAGGTAAGAGCATTGNGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCNTTCCGTTGNGCTGAATTAAGCGAATACCGGAANCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCAGTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTATACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACNACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATC
+
D+$.#:>;:,;G'*,@0"H#2:3*);9>56F?-)1EE*E(F1&@6C))!FF0!7,?.A'/79F%F7%.A=G%A9@A12"A(4B@?;*G9GH3628#?.B,!8-+)2B-(!6/=A6&GE@70!)260'=>@=7A4$A@%@5FH.3$.&!.H&9BH3D&.0:=C7A"1%(-4?0)@G4"0@0>'>0?7!,&9,@"G""=.C@=1"6.$EH#1>&1D$?/:<$/;0CBGF7+"94"1B9)-A4?;E6GED""%#6H6)&G6CA)3*9HE=:FE@6)7@<"!%/-:8D"G*+08D>*#+F34B%>:?##(F@D'B,:<>'1
@r212
GCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCANCGAGCTGGTTGATATGGTTTACGNGTATTGCCGGAAGCGAGGCCTGTATCCGG
+
7*"F'/(+<-@!/H!+>,>):5E.;@6G7<8($BF3276H;D%"7EC:?#.5<.&082:78,EE32G8-2D1A$9%,%@&6!CE1!$<-<9.F(2-C%80.'64'6<:D7DFH
@r213
TGNANGAGCNNNCNNTTNNCCNNGNNTGGGNNTNCCNGGNCCNNNCTNTCGNNGTCNNNNNGCNGNCNGCNTCNCNNNNCAGNTANANANATTCNAGATANGNGCCTNCNNATGGGANNCGGGNNNGNANNGTTNCTCANTTNNCAGGNANNCNNTNANNTTCNNACACGGCGATGGANNGACGNGGGNGNNNGNGCNTANGNCCANNNNTTCANCCCNTANCNNANTNGNTNGNGNANNNANGNNNATTTNNNNNNNCGNNNNNANTNCTGNNGANTNNGANCNGGNTANNNCNNNNNAACCNCTNATANGNNANNGNNTNTNCNAGGTNAGACNNCAAGNNNTGGTNCNNNNGCGGNNTNCCGGTNNCCNNGANGTNNAGNGGAGGGANNCANNCGCNTTNTTAAGGCANCCNAATNNNTNCAGGNNNCNCTAACGNNANNNNNNGTGACTTCTNCACNCTNNCGNNAGCNNTGGTTGAAANNNNTNCCAGTGNCGNNNNGNNNCTNAANNAAGNNNCNTTTANNNAGNTNNCNNNGNNNNNGNGNNTNGNNANNGGTGANNNGGCANANANNTACNNNNNCGNNNGGNNGNANANCGTNGGNNNNNNNNNNNTNNTNCNCAANNGNGTNNNGANCNCNNNTNCGNCACTNNNGNNGCNANCNNGATNCGCTNGNNCACNNCNGTGNCGANCAGCCCGTANGCANNNNNNGNANNNGTGCNNNGNTCAGTCNCCNTNTNNTNNNNNACNCNCTNNNNGTNNCNTAGCCNNNCGGNNNTNGACTAGTNNNNNNCANCNNNATCCANNANGGCNNNANCCNNNGCTNNNCCGCTCNTAATNGCGTTTNCTNTNCNCNCNCNAGAANCTNCNGNANNNTTNTTTNNCGNNCANCGGGGNAAGNNTNCGTNGCTTATGTNCNANNCGNTNGNNCGNNNGNNNCNNCNNACCNGC
+
!#""!#"$#"$$!"!""#!$$#!""!!#!###"""$##!#""$!#"$"#"#"$"!!"$!!!"#!$!#$#"$"#"$#!$#"""$$###"$!""!$"$$#$"!$###!$!!"#"#$$"!$!"$"$!$#$$$##$!$!!!!!"$#!!##$#!$!!!""#""!"#"#!!#"$#$"#$#!$"$!"$$$"!$$"!$!#"!!"$"$!!##$$$!#$!""##$$$!$$$##""$"!$##$#$"#$"$!"$!$"$###!!""$##""#$#!"!!$"#"$##!$"#"!#!#$!""#!!!#!$#"""#!!###$!!!""""!#!"$#"####"#$#!!##$"$!!#"#!#"#$!!!""$"$!#!""$$$"!!#$#$#$!"""#$$""!$"!##!"!"!###""#$$$!#!"!"!$!$#!#""$$$$""#"$""!$"$"$$!$#$!#!"#!#""!#$!$!$#"$!!$$!"##"$$"$"$"##"!$$"#$!#"$#$!$!##!$##!$$#$!#!!"""$"!$"#$#$#"#""##!!$$!!#"""""#"$#$"$$#!#"$!#!$""##!!$#!"$"#$#$#$$#$#!##"#"#!!#!###$$!$$!!!#$"#""$$$"#"!$!""!"!"!!##!#$#$""!$""$!!#"!"!$"!#!"!#$!"#!###"!#""""!#$#!##$#"$!"#$$#$$"""###!"$#$"!#!$#$"$#"$!!#$"!!#$$!$#!"!$$""!!#"#"!$"!!!"#$#"$""!$!"$!$!!"!$#!#$"$#!!""#$"#!$#"$$$!"#!!#$$#!"$!#"$!!$!!!""#$$$"$"#!"##$$##$#"#$"!!#$!!!!!#!$#"$"!!!#!$$$!#$#!$#!!$""!"$$"$$"$$!$"$#!$""##"$#!$#"$#!#!#"!$"!##!!"!!"$$##$"$"!#"$"#!"!!#$!"""#!"#"""##"#$!!!!$!$$$$#
@r214
CGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTCTNATCGCTTTATTACCATCCTCAGNTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGACGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCGGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGNACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAA
+
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
@r215
NNNCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGA
+
##"%)++')%+%)+&&&#'%$$(!%'()+!(+!$)#&&*"%"+&&)+"#!!'*"*)%##+##+*$&)'*'%#(%#**"+&$*'*%!*%'&)&*&'%&&%&*"&)"*$!'$!%"("
@r216
AGGAACCATGATTGCANTCCTGATTGCTGCCTTGACGTTCCTAANCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATNACATCGGTAGTTATTGTCTATGCCCTTAGTTATGTGGAGCTTGGTGCTTTGTTTTTCTGCGNGTTATTGCTTCGTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATT
+
58%-!<8<6'&?AC)B8'057<<E0)/!?H)E9FC6"7@>)0:30&/65+B39,.H6-+@A'';3>458<C!3>$15?B<(9)F'+*<C0;'""$$-<A,7@=GFF>#H4*<GB/3!1(.-B<4EB=::H&$4?'F".@1%7G%#C<2AG(7+$.21)*2()67,7C-H"#A>1EF#+;/D$D44829C9/;&3;)H0)C(%<)2A4E=A8E;$99)-?B74(4+*;D0F5.
@r217
CTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCANGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCG
+
-F?A+B(;61+F'A7$#'A;1BD/D!?0;61&(4()F//63D+21/91<.-@3(C%5H"9)97&0/0;D<<B1",4HEE-;#=$-&0'08%89=G,@B:F0$@765@?#.!0,*)//17<9F,+73%$!(&/2=95&AE30D76-38H$"#?#"A$./3"6FA<=);',)+H>.EC*F9D5&)(8(GDHE:@+".D=%
@r218
NTCGAGTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTTCTGGCATGCNCAGCGGAACANCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCAGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACCTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTNTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTNACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCG
+
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
@r219
NNCAGNGNCTGACGNCNNNAGCGTATNGNTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCANCCGGANATTAAACGGNCGCGGCGGCAGGTTACCCATCACCACCNAGGCCAGATACTGCGAGGTGGTTTTGCGCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTAGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGNGGTTTCCACCANTCCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTT
+
&(&'*%%##&%%(%"'!%"$()('%&$)+)#)"$""&$$#($#$"&%&+$$!(&($)"%&!#&**&%'&"**!!&#"!+&+"('$$)*(%(*(#$)!!"("%!$($%#'&)'"**#'&((')(*"(('$)'"#+#""%+*)"&$$+*$*!'##''++"'!#'&+&+#!("#)"$'!(**('*")!##(!($+"$#%!')'"&#'(&'#&)'"*&#'%!#*#$!!"!##$(*((!"#!%&!"!))*""##(""$$)*%)%!"!*$&&%"%!$)$(*+')#"*"!#("')*#"+!)#!!%#"()*$$#&#($)%")+)*''&'%!)!+#%&)()%+#
@r220
GGAAGTTGCGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATNCGGTATGGGAACCTAAGGANATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATA
+
*?><GF,9@+(C2&-(64C73483941D%F?5$70FB)8/;+8+DDD*B4B?'+A@==;9?/'D/<@43?91&(*E65*?B!)BH@2&%?=7%;;2$5%E@D$&8..D0+E?$)??C14>F1565C8>:$1@'G1F(8?E:%0E=)%3!6@,!.D/
@r221
CAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGNAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCC
+
2,3*'27$%*"-?48FA,7".>FGD-G%#E@8*!B:/6*/@$#4$'%@>)$E8<H$>6E(E,1!B203G1+4>!0@H0<<(#(.="=1H,(D#B#?41494GE:09$'92#7<:DA<'5B$#<&8)!'FB+2>'0A7"=)0/?H-A0'*@FF
@r222
AGANCGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCNACGGCAGCACCGTCGGTGGTGCCATCCCACGTAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGG
+
.,E/,@(.B"6;>*D$0"4GC-!,86:'F(G:@.*8"82*F#&1G-E?/?$@3=H?C)"7.%H@AC-*9D)D3&953-(E,<:53H7/H1.67$",<+!747A2568<":G#E==<H31)":G#G0797::$"'1='!&D&."G1=A9,8BG'D921G*-5@;?.:CH1-<B3:/%+;103+G02#1-D?"G1
@r223
GTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCNCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGANGCACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTNACGCGTGC
+
?6<7@?0CB6(+;6*(B87-+95E99..24/.8#+$;$:;8G99/3C8F$>;-/<.D0@C8'-F*+(5(8:6#B2*%D0$,;F8G6D%5F(D",>,C+839H9'#0C/3'*(C>&??6=-/2,*&#91!:6E%34>&&E<A<+3&A*';=3B3&B60&0D5+H*2/0B32$B41E#9.3E*&(+&B+>,'FD+!29&<+,(4E;/H.#!E/=$@?/.B*?$+G-8F?(F82=&'A%D)@##G97.;-1'2D*%+8>=HA>=;(/B3A#>4">723B$)@$1F&$C86D;3&%4'+4*@19='"1/&C>(=
@r224
NNANACGCAAGAAAANNGCGNNNTCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATNTTGGTTACGTCTGCATGTGCTATCTGCGCNCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTATTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGNAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGNGAGTGCGAGGATNGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAANCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATNGANACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCANCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTNTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAANCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCNGCAGAAANTCTTCCAGGTCACCAGTNCAGTGCTTGATAATAGGNGTCTTCCCAGGATGGNGAACAACAAGAAACTGGTTTCCGTCTTNACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACANCTTCGTAATACTCACGCTGCTCGTCGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCCCCTGGTCGCGGCTTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCACCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTNACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCATGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGNCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCNGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTTCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACNTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACNTTACCCGTGGCNATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGNCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAANAAGCCCGTGCCTTTT
+
%$%#'!*%#''%&*')""$#"'"+)((%$($()%('"&&'()!%$(*"#!#+*&")*")#"'#&')%))!'#*$(%*"!'*$&!)+"%(%(+('***)(&&)%(+"#($#))+#!!')#")"+)$#(!")&&!$!*)''(+%%"!$#+(%+)##$+)(+)*'##'!*#!*#&!$))+&+'(!"+*'*!#(+*#("%(*(*)%!"*$(#)*)!)*++&#&)(!")"&**#!('+(&'"(("$'++*!))$*"#(""+*$'()"!!&+(&+&$"+(+%#$($+$&%+"*#$+$#()%+(*&"'&)")&"#$&%(!*&%"!)*(")&)$#&()+)**"!"&%((&&!!)"#())%&&+(++('"&&+*+'"+"**((*&)#($%((!*'&)**('%+*$(%"*)+%"&!!&"+$*)(#*)$$($$)+%&!*&%"'%+'#$)('(''+!*(%"&'+**'(%$%$&'#'$&"(#%"+$!(+*'&''!!&&"+$%$*!)#(!(%&%%%*'*(*#+!+'*&&#+#''#)*'#)*++)+(+%$*#$"$)#*"!*(%&$&&!!)'"$!!(+!"$#%&'+&'#+**"()+#+%)((+*'*'#+**'#''("!&+!$+'"&%'*%*+"%$(#)$+*+(+')'#!"(#++!'!&&'+"#+*"""&)("&#*)#++&+#)!%(("&+$(*+#"(&$"%(%%""'$!#**'&+(++'+")'+&$*%+")''*!%"$$*)!$+$($%)'+%!$&'(&&*))('!$*%'"%%'"+!%*+++)+#$$&"#*%(##(*()"&+#*)"#("!'"*(""*&)*(#*$%%#&++((''$#'$'#%$#')%+%!#%)))#!#%$&#%#'++*+!))'(')&#$&+%")($**"#'('#!($$(*&'""++&%&))+%")*)$()$$$('!)'*)')'(%$'&(!+"%%"$#'+#%&!''**)#'()'$*!"*$$$#*$)*))'+%$)##&!#+!%"!)$+#*$%)#))&)+##"*$'$+&(*+)%$&(+!(*"%*($)&%+'(##'&!#)'#""!$!+*!)$"%)"+)*%#)&!"&('"%$&!#'&+&$#&"$(*$%%%*%+*))&%'"#!""+&#")*"'*)*!(#$'")**))("&$+*)'()#*#'*++'&+!)("##()($+&*"$('+#)*&(!'*&($#""+&&#)$*"*''$)(&%(!$%+&%!"()!$!#*!%#"#'"&)(%%#(%(+#+%%$#*!#&&'+%*%&+$*&((#&&%"&'&*("!)(!%#'+!$*"$'"%"&''+#&++'%*%+!)+#')&!#&%*'&)$!'+**&!#$&!##)&$)%%()+$#()")#%#$%$$**'*!(("!"#"%#*"&")+**))+(%!&')''+&''&"(#)'(!+)")(#'$'&%*++*'*!+'#!(#&#%$+$!$$((*'$+'#&($#*#+#"&%(#%)#*(!"!'*$&$%&*)+*%'!!*'("(#+'!"%%%&$(&$"&#!"%()')+#)!+""(&((!*'$+")%!")")$$("*&!!#&'$&$%*+$'("&'+&*(*"$#(+(#')#)+#$*#""#&+&&)#!%'""""#)(%"*'%")#)##%+$(!)*"))"%%&((+$!!*!)'(#"+!"$'&"!($)$&+$'+%$!+"!("()&"%(($+&$)&(!)'('$)+!%+"+$+*"+&%%+#&&**(!"%))#'*%&(*("'('&)%%$#)'#+""%''*+*#("*&)$"+)***%$)(&'(*)&#*%))"'$#*%!+%"*"%!")#(+$+*#%($*'&%&"%(*#$**%+!(%'*'((%&!*+"!#()&(*)$#'$+'*'(&&+("!!%(&(#%("$!&&%)(&(#*'$***$$&#'&$#"(#()(++#"$#+&#"$!!#)+&"')!+**'!"$)"*"&%"#"**)))+*$'"$&(%#*%)!'&%&""&"!!*)))"()+%!'%(!!%!%""%$!(""#'+**$*&'$"$$'&'*++"!&$&)(*$)$)'"'*$'+$&$'++%)#&$*)#%*))!(!)"!*)!*&)*%$$!""&)!&'!!"**+')*"*'&#*'('$((%+)'*&$)+#()"))*%#(!!*'"$(+&!##("!+"+$(#*#+%&++(+#")*"##)&$!("#&%!$!#"&($"("#"!!(#'((&*#((&%
@r225
TCTGNATACGTCTGAACTGGTNACGGTCGTGGCACTGGNGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGCGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTNCGGTGATACGTGGTGTTTTTGAT
+
0F,DC'F,95>.((!&#9$40+29/H<+:1&C%++B<.'7FB564@8C'D?14'%+7#3E$:9-2)-"='>F115B2':<F%.??-3@0=;?C6=,(8=-C<26E5F/&G;HG="H.07-*A'$=-;:,GB@>.29<*H,;',&-#@&=%C<0E'3=&3,>"E">0;)B(:;/%@"3--/&-1''<6&?.+1HGH&&1*8D+-/#E)E"1:7F$/1=(4:=GF-:-:*:7<21+F3&0>:$&8GF$'+"D:-//@GH#F#EADAE3EF5195,$D@D$'B+%.!D/3,8%)B?GC!/&+>6H2(9E$7C0H*/5
@r226
TCTNTGCTTGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCNC
+
?1=%./488!%7%8.84"7-.,#8.?&)&.=A&1/BC-':B*7&+/:C4*D(<!&3H580"
@r227
CCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTGTTACCCCGATGGTCTTCNACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAG
+
1-F"+64(A/9;'1A>@7G@(C=$77)C36+H/@6&D=9HD*;4&-!ED@H.4(/G((?6<!F/$/G*FH;2;C27GE;C*%H95-B-$BH4A%:-(/<.(=C+CF@.CB@+)FB-3)%5H!HC6A?1)/=:#./6.#4*@>8++&'>.09$D=B,6!3B!D05%BB'>/8G'6-:8(1+3<A;4@6&=-7;1+
@r228
GGAATGCNCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCNCTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCNGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAATAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGN
+
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
@r229
GGCGACTCTGGGAACAATATGNATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTNGCTCAGTTTCTGACGAAACGCCGGGAGCTATGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCANAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGNATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCC
+
<E418E2:(1/<547?*1)@&C)2$.CBDE)3C7,?3D7G6;E@&,/G2%=G5"HF+<C7$;4?F5A)27>7&GEA;'$7?%*%G-#4;B6&.."-+!6C#:#6E-$A;HC,(?,?;3D0-5A1%1=$(>,2!469C!81/<12/#'?#,+=41)A"=E-95#$:??HD8?>9:&@-7>";5+F*C@!A$2238%$4<"@F2A@:2%8-&?H%;@BE:%-)E"/2')*>9E5"CE,A2,1).*2,5$02.)D:+CG;3E,23"7GC2!6@2,E77.905#A:<581@"8,D%<)=/=)72'+6<-?:>6*-F151,B<+-=F::@-9=95D+<2E6:G7=$-F2&!?C/;1F@4FF$+"A$-;FF!93E1<;9B#;B#+4"C."=C<=!F5/'/>E'!:AD3!,;)*41#>B*:DE;A@$=)#1EA-0+13E0#>(!%-*!%$/H>
@r230
AACCAANAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTGTNTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCNGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCNAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCT
+
-1'*2#452-0-E7@"AG>>%%$8.H4-9-B',CB$#EGE04G/-00$D+).1BCA'&C2<2)*F*%'<=<0AEH-'0(8+.AG=3=/(G"85D@3%*F271@/04C(A.8...E#3#2F1;(),5B).:8,#?H,2>2*>44-31$.$"/<)/3;F9*G/"+=E5#9ECB,24.?+&8:3,3%&A77E12="2(C:9.:5'!!666<A$'<2,82G)?!1BG9-G=#E8(3+5,5B?@##+9/H$$"6B<=DB*$7>G9DB5"2H7>C@F>=&2G*'=,#:;A(%"1G;)1<35%=
@r231
TGGAANACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATNAACATCCGCAGAAGACGCAGATGNCGTCCATGAATGAAGCCGTTAAACAGATTNAGCAGGAAGTGCTTACCACNTGGCCCACGGAGNCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGANCNGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCNTGCTCAGCCTGTTTTTGAGCGATCCGGATATGCTTCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGCTATCCCCGCTTCCCCGG
+
+!(&#'#$!+$')%&!&("+*(#$"*$*#((+$)&+*&$%(%"$*#+'#)*!()')'"!&')!!"&"#*'*"'&!&!)"(+"')$$+#!*%'+*"&*$!&**)($$"$)*$#$**)'%)""")&#"%$")!&)')++&'''"$!((&!#(*'&"%%$#(&'#%#%*#($*&+&(%#)+!+&&+&!'%'+)$$'*+))"(#(&'((*((+*)!)&'%$(&((+#%%$**&$"&#"+&(##*+!'&$**'"#+!"%%+"'*#'+(#&%'##**!+$*"&!!*)'*&('+#%&%+##)*!%*%'*#%&!!&&("&(%#'##'&!+*$&"**"%$)!+"!+!*+#'!+'%!!+"&&#&'!$$*+(&&!"$"%+**#$!!*))")+#$(&)&(&(*'+%(")&(#+++)$($++)!++!*+*!&$'#&*%*"*&+#'&%&)!'!)!#$%($)"%('$(*$(+)&%!#%*(*!'#$&#+&)&*+!("**++)$((")%$*%"%*(($#++('#(($)%"*&!'()!&#)(#+)")*)%)"+&')')*'+!*(*)*')$)%$#+()+%'!%#%+%!*##+(&#!)#""'')*&&+''!!%$'"'('*"+!)*
@r232
TAACCGGCANNANGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACGGATATGTCATTGNATGTTCACAACCTGTATCCATGAGAACGTAATGCACGTCTTTACCTGCCCCTCGCTTTTGCTCCATTAGCCAGAGCAANTATGCTGACGTCCTGCCACCNGAGAAACTAACGACATTTATCATGCAGCCCTNTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGT
+
(''(*$*&'(&*+*&"!&&)$($+#***)(!)++"#+"(+!*&'""+%''%+"!("#%'')(!"!'(#"!"*'(+$#+)+%*%&*!("#'"&#"(**"#$++)))*%*%$*')+!&%&))!("!(+'**'"")!"&+)!##(&'$)"#$)'&++)"$)#%+"+!!!)&&'*#('(#%()+!(#$##"(#"#!+(%*'')&("&'(+&"')$)%)%"(!&*&+'$&*$+++$'")#
@r233
CACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGCTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCANCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGNAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAANGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATANACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTNCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTNACCAAATGATTGAACAAATTAACNTCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATT
+
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
@r234
CCACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATCTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACNCGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGT
+
!*/#&716A+.>('E)#3#&+5H48/"'".@#%'/H>1.?D1E3/B333&C/'AH>!-!A!D87>$%@%5<$5CD)3HE?%9"#F7$3(F0@H&*F4EA;FE,':%)0'*1#4A)+"$$GD+6!!07'@1A&!B.'!C(3H!?GE$D-5/11*9'@/DEC#E4.G?F?=B,!6+,=,&$.7D-#9G5.@/!E#1%7/C38E5*E,&@5G2DBA2&?:B)<F,+5/<E*614!%<+&'4&5*#5+*>:.-<%:*7:+$?6$6BC)3:/F:/!""E'?B0+3'HD$"C4=9+':F5&D5+15/%/?//6C).2,1:2-0<9#>'F(@'#$(CGG:3AC;/+18=F3(%%?=@2*A7CD3(=7+@,H'6!&/@:+C/)'?EH915,D'@+(5920@D/;A4=,F425'9B-$C6!,,A'6-6?494#&=+G8'#F*.-+1<ACD6:!?*>)#,75B$9G)/H49;2F6(AD*/#*0>G''G2-@C-&9
@r235
CTGNTTGATCTTTGCAATGATTCNTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTNTNATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGGTGGCTGGTGAACTTCCGATNGTGCGGGTGNTGAATGATTTCCGGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCNCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGNAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCG
+
%1G0=5+4H$>%3(0<&C+.A#:??H@FB+F$A;),:>#B/C$D+76G>32$7D692''"+F%B0<72&&H1@>8'D$$(07!+0>/08.*4;3;:4A4/D09H?B1;@;-3"=6H6.09"D%,3%:=;<0,;8#)"<?.*'AE7A5C"2==1:*6?>D0:H%:)DHFF6*3$-;27.+?E+C6&0C>190.#*26/4HF4E3E:;).1'7+)7">>2H9DF4/<H@CB/F.=;B%89?01B$,A<7G37B<,*&.@$@&++85C.1G!6?E!/=4?'EF!3@/@A)D''#%E7#5B<*29.H".-:!8,E'DH89-CB(:0(#>'H!/@50A@.*B3)@#+368?'0=B6264-F!5"#7(+?)-6H!F?(F/8@64A6$);<';-$,4-H,>H'F:-30<"0(6A8GDB.A98D
@r236
ATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGGCGATTTCAATTTCNATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTTACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCAGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGNCAAAAATAAAGGCC
+
7D.4::&*C0"-?/G*,=?ACD/3,F?'6!.)506F;A@F/*7:&*$B@'3'0A<!2G*<'.57A?:+FA./%!0?3A;'%-@9%:(:CB/,%+!-:(B041<23>.H*+5>%93806+?&+F?<+#46A'!0B!2,9.#C;3F?H2??"%"-*513A""9!9@E*%;;F*9E<=0:&*/(6/*G;F"=H<!4GF9*>71061@!:$:;&.<*9A%2<&HD/6-AH3E$8"+#G8A?"7//F7#-323"B#@(H7'6H1@D;)6,#.H0.8F013;A))!))@'*2%&:;1/?'<+/,81.-35<1"",44=C&C'C()&D@4C*9=/E8))86;-=%'/6>#::H
@r237
CCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCACCTGACTGTTCGAGCCCAGAATAAAATCCATCGCTGACTGCGTANCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCAC
+
63,(G;1-B668=A'F$-G/@,+25).%5<B@#.6%54@H-D.23%!1BBB8!(G'BEFG;,!12$':?D?H44679@:0+CEA,9C&636(AG@2/0',!,/2*;7+6B?G#DG=>36'H(?">+BC+31+>=%*4*?=6$/81"(,
@r238
CGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGNANGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCAGGTCTGAAACGCTTGCTGCAACGCCAAAGGCGNTTAAGGTGGTAATGGATGAAATGAACATAAAAGCCCACTGGACAGTCCGGCTCTGACCGGAACGCCAACAGNACCAACCGCGCTCAGGGGAACAAACAATANCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGANTACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACANCCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACNGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTAGGGCAGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCATGGCCATCAGATATCGTTCCGTGTGCCTACGTCCTGATGCAGGGGCAGGCGNTTGACAAANCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGG
+
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
@r239
NCAGNNCTGNCTGAATACNACAAACAGATTGAAANCAACCTGNAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTG
+
(&*%%&((&&)*!+("%%#+)%(%))%'*%""%%!(''"+#)%#&$%'!%&"*"$+%!"*)%")+("(*+*#!("!+"(+'&'&!(!"#$&$!**!!()%+(#$#*+""$%*
@r240
GCANGTGAACTGCNTCCAGGCTTTGGCTTTAGCCACTTCNGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTNCAGAACGCGNCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATTCCGTATAACCATTTGGCTGTCCAAGCTCCGGGGTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACANTCCGATGTGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTATTGCACGTCTTTACCTGCCCGTCGCTTTTC
+
"%#%$""&'*&'!!+*(%%$'+""('&%&'$%&)&#+!!+%#)%#####"(&"*&#)!(&%%)'!'%''*#+'&$)'''$')""+!()((&*(!!($"'%"(#%+(*!!%'**)&%'*(%+)%+*#+$*!!+#+"'$%*!(!%&"%!%)'%+&(+'%)&!))!&%$!'!%(&+)!!")+%((!!&'!)+(('($&"*&'(('+))!*'+*&&!*''$)(+%+%)&#!)%!%%&($%!"##+$&$+%!+!'+'&')*+*%#"#'+++%)))&(*"&)+*+#((**+#!(&(%&&!%"*)!&$"&)*##(&%+#&'!#%!#)'!'*""(($($*"')!++)*"$'!!'&*)+#%+(!+"'+"+)'+*"*#"!$*$#%('%+((#!"'*))#*("+(!'!$"""%+"'%(
@r241
AGANNAAATGNANGTANANAAANGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAANGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGNTACTCGGGNAGGGCTTTACCTCTTCCGNATAAACGCTTCCATCAGCGTNTATAGTTAAAAAAATCTTTCGGCCTGCANGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCNAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAAC
+
#('!&"*))'')#)")(!'!+!'%#*''&"))%)$*)*)(%*%''()$)"'!+&#!%$#%$(!*)!)'(!$(%()&$#!*+%**('!'%"%"(*))%'#)"&)%$*'+'"+#*%#%""*#!*)##!!''%#+#&$"&$*$"))$+"!'%%)#!!*&'#)("++)'+"(%"+(%"'*'(%'$''"("''!$&(+$'&#&&*(&(#%$+"##%+")#+!(+%%()+")*%+"'(#++$'%!*&+%$!'&!!%#")'$!+)("%+%!&'!'(*+$!(!)&"++&'$%%#"!+!+'!*(#"+
@r242
GAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTNTGGGGATCCTCTACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTNTGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGACAACAGTGACCCGGCTCATACCGCAACCGCGCCCNGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGC
+
90(6#@-&!&&*-3+H$3#1?':>:=30'=(461B7H7F49)%C6)5A1+?/A#5C###78;)--!#.!.)**(/>4$0F4C7B81'9=$3",B7550A"(=@;*C>--A,@#"/+("8G,2>@7@2$HH9&-,6'G;'5<)64:>2>?G*&2*C",3#,;CA;2=9D;47(1(C2H6A'=<59:(?C9'$<F";1@G&@52@8#;<CG.G9=GH93$#$3=(7%'.2'&*-&&?)=2!.'9;&)3*5>G?B<%#95EG618B%5@3<4)$1E>BH7><=$2>-$&B>(@4E64:83!)*(5.1BB!H<*F04<A5B2F8AA7!H?D7)(AGA<-F$@4667#=$E&B$F$CF21*.20<<@F=$E"CBA%A?=5G%$C@C-"10-3&.+.AH%2G!+&$:$D25=C!G-H8FC.'%2&,*!+.4#E&-=-1!
@r243
CTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGNAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCCTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATNTAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTNTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTG
+
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
@r244
CGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGNACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGA
+
>8/97678H,1<6;CEBH1#<A-(H-"$*HG,"&:4%>7HA7&F5/=+4%%9!@)++((F"H"0%D39G,:&HC(?.A8A0/#%?&7FH<*&%/E@'$@-B&(8=AA@9@&((B3BF)66%"3H''!'-21G,.+G>'")(':,"E;&D;)+/!69@>-=,;1"?+0G6+!88*98#,/7);,G13-+)0$.-'<5;A<'<F71F
@r245
AAAGGACCCATAAAGTNATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATACTCAATTATGANGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGNACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAANAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGNGAGNATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACT
+
?=4/#)8A;"E;."9..)#(/=C,#1'E$&>6G20#'-57G4/9+1AG.@<7,!7"<:1G&,7)B<:+/G"<D#+$*'3=0H;->0!53)4.<+"3=,*3$/F,/(%":6@D"7,,%A0!$F(>8C/;";3/#<!C:=C>D&F7E0H%.2(1>G:)-D*$=3(=8/#)A2*"'8D9),:"A?5.E2#A(61G!-((!A5(@+9D2-8CEG:).*#";:!E!G%5)<)3.A#7+**$C6@.$A&3@H6F1?0E54CC;C92#C<@&/=5))%<?8*3AD='&%!8C=2=6.D>#;(?E$#4C$=7EC',15!/%@B#-0F")D!)=0>;:9!6DE1-H<3/5=?C"$>'?+)4&*-C(HH<;&=188F98=*"+&AD?$#037,=051;A31?H3B0'4&2A=,,3HD'-(<893%9D(7>
@r246
NNGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGACCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAANGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATANTGAGTGGNCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATNAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTA
+
!%+!")%()#'#$+"##*"'+**#&''""!#&#"$&&($*$&$(&+"#+)()$(!*!''#$'%$+!$$"%$#!&&)&*"+'+*)*)!!%$!*!!$*#$+*($')+'+"&&'+!#)!!'%$)'$'!$')"$'()##!&#$*)($))+!)!)+#'&%'&+'*"$)*%*!&'&*+&%)*'&!%&($'#+$%&&""*#"*'+$&')!*)#)&&%!%+)&%&!'###*'&##(#!&&+$('"%"&$+&#'*("#"+$"#+)*%&!**'#%+&##+%$""&#))&+&*"%%$+*+!(+#(+$!)"(!$!"'""+%!##''("
@r247
ANCTNCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGGCGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGNCACCTTTCACCGGCATCGTAGGATTTGGTNCAGGCATAGCGTCCTCACATTTCATAGGNAATGCCATAAGTNAGATCGGCTGAAC
+
(*D<=+&"-D.&C8>+.H8::0!1!E(A#:G"62$!@:-D9'/G2C-7%A2G8<#26(0%G+@,G#)G++>,2!?FFB<+6D6EAC*/HF'7$AF!96:!'G8>;2=8'5==#:,6G.H'++%'G,%DB20F:;74+%<:471?$02<=18)G1/=00>$#E=.?.3?49>A=&5E$:9*&)<!AE4*,5),BA)H/+%&/<)90CA6G*E?-*F$"A6+()!(*'-;GHA"3=*:GGD3
@r248
CCTGAACAACTGAGCAAACGAGAGAGGTACTCCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCACGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTC
+
=,%$426/!,186.<<G$=A,?#D/-;8<0'9<,-3?G,2%!57G06<0@AAE)$@"A5'>&4:3/!)A9.'&++:>?-/.H0-4:<G<#"&*%G6/-1''BF0$(:#97/>D0:6E$4!'-6B-%/D4=1E$#"
@r249
CTGTGGCATAACCCTCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAGAAGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGAGAATAATGCCCCTGAACAGACAGAGGACGNCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTNCCCTGAAAACGGCGCGTGAGATGGGGCGA
+
D>/!9)E,"!#7A8&;7#%.E-B*+%5)2="%$F?*?/?%E08EG<2&D.:GB#@%>$.B"B6FEC(<,2-B!</$4F)E!;GF<0=%A%28H,(>)C-+-0.A#D@/)$)?>86A;!%)2E9>'!02+)4::-6&D"F3A<$#,5>873,<#8D,:0HE)B:"D*)8+"1/C<#7*,$!8G@.?GD(<@<1FEG:.*%4&$3-0-*!5B$+"<&$0,,F5GDC'4A0*(<D"5F%*#%7.HA)<01!G0&GF7617"4?@F=D*5?8!
@r250
CCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTT
+
FD#7.:"D2',+H?3:H19?@"+'F,%H0756EA3%6:*:"4B6*D=;#?@
@r251
TGTATNCCGGTGCTGAACACTGAGGNGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGNGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATNACGTCTGCAAACACCGACCGTCTGCGCTGTACCTTCGGTGTNCAGGCACTGGTGGAAAGCACCTCNAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGANTG
+
%$*)*#+(#$+#'!""!+)&*'+'#"*+*&%$)#((!+'%&#*(*!$'!%(!*$)#"""&+'"*''#!""+*"&($("&!&!")%*('"+$$"'+)&+''+&"'+#%#"%#%('(%%$%(+'++#$($%!*&*!)%+*(#+&&%%%##'!%#%!'"(++#+!'$++$+)*&'*'"+)*(%$%#()+)(&$"!+%"''#()(##'+((((*)!&(+$#'!*)$!##!"$&#)#*+%%!!%%)!&#&#()$"$"%+&#("(%$)*"+))")!(+!#('!!%"%'+((##$'%'(!'+)
@r252
ACGTTTCCGANATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCNTTCCAACCATCTGCTCGTAGGAANGCCTTATTTTTTTCTACTGCANGAATACCCGCCTCTTTCAATAACACTAAACTNCAACATATAGTAACCCTTAATCTTATTAAAATCACCGCAATTTATTTGGCGGCAACACAGGA
+
)&"+#+(&)#+'#*!*)()*+%*"!"*!'!%&)''"#*"##"!)*")"$&*$$$"&'&*!%%+(()#"#'+")+%"'"*$'"#!&$&'"(&(&!)'*)"&**")%+"++(+!"("%((*#$"("!$#(+"%#$!$*)#*)$""&$*#(*'&$#+("(*"+#**(&'##&)++##!((!$%+#+"!!+('%%***"$!(((')(+'#++!+*$(%)
@r253
CAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCCTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACG
+
!F:F+"GB#46/>&/!?AE+>18!0**561%$;+B"7)<44DCH!57+!!G$4%2E!@.%;C!H@7">BF8A*!0?&;=(!>*#A*<G&@?-!'4:8+0/2($<":4)82/@F
@r254
ATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGA
+
9,8$2."6>9E)H4,/"#H'/="=H146"D44-9%:8'1'*=H@3-B"B$99>'@=>=)#="A$1'&*-5).15"@C9H6C#E@&
@r255
AGCCGCCCAGGCGGGCGGTTNAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGTGCGCTTTTGAAGGTAACGTCACCACGCGGCGGACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGC
+
/<A&@>0$2+(9"".45%1>5&*"CE&+/GD%@FC>D"<$->&$*=G&;<2"EEC8+F-?(1+D),*@'A<*2!$#BH/B(5(+=?+?:/#+49&DE?HD#E$%9=#8:;,4>EG0A0:>)."@DE$;--GB)D3H,1=6<9'!(-"'66'EEE$<.=((0E0#)+9/+7#$2HA8!!:;)/8-1G">5*FAEH>)A,+;<%!4H5.6#)GBD%74H774>.2<&7@E3131("!)+%,,81/@$)$&-5-5A*3D!9*>'.A2-F6.+=%E7$61838H*<(C2+<'!332@5$1D$9+(*F&09C5;#)-1.H067B-4':+;499D0)@:F2,;3A&G1<CB'"2'BC(5F247<1"%8>4=C,*9?-AD<,16;',*B#+095'$?;<0;.
@r256
ANCCCGCTGANGCTGNACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCANTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGANCGNGTTTGCCGGAACGGCAATCAGCAACGTTTAACTTTANNCTTCATCACTAAAGGCCGCNTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGNCCAACTGCTGGCGGCAAATGAGCAGAAATTTNAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACCAATTCCGGGACTGGTAAACNTGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGANGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCTCAGAANCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGANCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCNGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTGCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCNGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGC
+
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
@r257
TCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGAACNCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTNACCAANGGCTCAGGTTGCCATTTTTAAAGAAATNTT
+
AEDF+B-)H:&$H5D5D&484+/3821?5#@'(*A:F4.>99HH<"+C%6#/#<,5+)/;$"G+7A6C"*=384&(H@,76!0D78)E+2253(C/%#>C&-=-7960H9>$6>E>@+1:4%EB26=39(A:204)*($5%+8+7#%"51D=>:?6").61'E+H#@5E?EC5"+12GA3;@@%*B7'H0@2>7/&@;/>D,9"5165?A!.:;?7:@CE.$;-@B-84<(#5.0@:F:4FC&1,G6A.D4!HB$''5<-@49'C?H2:G&:';!B"!/G>:FC/#7H.;)916/0.)71(9B)+/%=<(B&+C(4"0+&'1G#C&!C@32)/A6$-E3#1H-
@r258
CTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCNGCAACCCGAACAATACCNGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCNAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTNCCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGNTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTNGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTNGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACC
+
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
@r259
CCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATNAACGGTACGCTGAGGGCGGAAAAAATTGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCNGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACAGTGACCGATGACCATCCTTTTGNTCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTTTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTAATGATGAACGGTGCGGTGA
+
:*4=B2>8=9=00/D@$7#:E9H!!/<87&=$DF8%(6):.?6C)A/!/=C&,A:!GG20+D#(11?@C8>"!36<EH85*<<*$3(,<A0C@?,:F.1F16)?99A5!1H*H,+.,+.>B%'<4?</711F@3.42.D',:H0-F9F6?@-95E":70A,C>>(7G?A6($H05G=2G74!G1'34<&%86$<079=?H'+4%2G.@?;6!+()0<6&19;DGF@>!D+F.7H1:59!C<4@5:>0%+*H."H-/4F#&24G.5"A*A#E/6?%#",B;H>(9AC?%6@-*4-54(#BA4!4EB5(5/&7$*/;)+%#'+543D788'+1??>=:D'G"C:"*&>7F;>.618C(796#1C#&.C!-.#E/1""B!>5281F4@(F)494E<4*:'
@r260
GCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGAT
+
22&(0H*:!,A<B3$1-,'%;9#&E.E"#EG33#<=92:"F'AE:7*+/E#?@<G*BAC%H#D6,:!,6.6%G9*2:D.4(E0%32$--(B!.:<5D,A="90;@-@=+F-$.B8(
@r261
CCGTCCACCTCCGGAGAACAGNCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGGGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGNCAAACTCACCACGTTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCNGTCNTCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCNCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGTCATACTGTCCGTGGCGCTCTCTTACCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTGTGACATGACGTTATTCAGCGCCAGCGGATTATCGN
+
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
@r262
ATCCCAGCGCCGCACCGCTGTCANTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGGATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCNATGA
+
9222+#*G/A-B1(?H:?@A63=B?@73A"!B"'!0+>6;8F%-477A,B8,.,@B=>:13AB(6$.G#85A.(300+.271"@G3G)FCD".,/+.84'D83(;-E8+@D1C=:7#:<@C5C8EF@!AH'@E<'#0,/C*$#9@85"?0&"5-,<11A!!?1.F";0"#"5*=H=4/4#AC=:642%6*+)*$D,=E+@C=5&2"6H0(HDH)>B7A2H(7"93CA%&>8?B03$9C>,>!#E13<BB:C5.8;EB)>E#%.G?-(<1:8+?/$1A2(%#+(D!!G+G)G-A?3?3D$%3-@G6:CF>*E+@95(2$0G'*90=/#?AEFG-?A35%#:D0$*
@r263
NCNANTGNNTNTNAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGANCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGNGGCAGATAACATATTTNTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGNGCTNTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACANCTCTGAACCANGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATC
+
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
@r264
GGTGGCTTGTTCTTTAATCTNGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATC
+
BECG@!0?1A-0H)626E0C2:$FHEHA2D3;4='!'!>18A<H4!7*.+BC#"?",!A7%,9D,$#$E'D7!8)-B-9E/.776&&HD-6G.5%(=15/?7.:.16?*(=:B1<@")(@96B8-00%7?35.-6"H*'-"/=G&@67'.7<&H33H94>?#)3E"9)F?/:
@r265
NGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGC
+
/'-'A'2%:>'",/CA,+=.610H96E+*'-C(>8?@C4"0*&+E*;4$F98!*1&*>(G7B60C.5;#"?.478'FC(#:GC<5=='D>
@r266
TCACACGTTNGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTCGTGAG
+
7!#:*3/>=$$61+*&H@?#:#G&@+:GG)7.,7H-:5A9DF'7)H)H=+4H%.A/>/$F68FE?25%@6)#>3A48F+1+56(CH+>((B=BA+)):'7H!=-'C)<@4)5+$@DF;".%6
@r267
GGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCC
+
8H:<$))E1;'&#EA5/26*3:(0:5;/<A+//$,4&-G8,%?@84.,>1,B>59::443E42"
@r268
GGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGC
+
9!5*/;D,F-@#2:3#<B7E4H+)9DGH%?.:"39%(>!7;$$;9*/3A@).3)G2>EB-"@5>3;7#E1F!8"H-8B@H>,76<'!*G(.,9"G15GGH=%D13$+
@r269
NNTTATNGGNNTNNGCGANNCCANCNTNCNACNNCATCTTNNTNTNCNNNNNTACNCTTCANTNNNANCNGNNNTGNNCAANNATGAGNNNNTGGATNNGNCNCTNNNCCNNNTNGAACTCGCGGCNACATANTANNCNCANCTNAANTCGCNNCGACTTTNNTNNNNNNTNAANGNNTNNGTNGGTNNNCGTTNNCANTTNGNANNNTNGCTTGGNNTNGNNNTNNCNNAGTANATCNGCANTTCTGGNNNNNTNCNGCCNCGCNNNCNNNTGATTTNCCNNNGNNCNTNTNNCNTGCGNGNGATNCCNGCGANANNCNNANNNCNNNTTCCCNTTTNNATNNANTNNATNGAANACNNNNTNCGATTTCNNNNACCGGNNGTGNNANTGGTNACTNTNTTNACNCNNTACGTNATANGTATNNNANTCANNGNCNNNTGTTGNNTAGANAGCGNGTNGNCNTNNNCNTCTCNGNNTNNGNACANNTNTGCNANNANATNNNNNGANGNNTNGNNNGNCGCNTNANNNTTAANANNNATANAANGCNNATTANCCACAANNANNANNTNATNTAGCNGNTNNTCNGTCANGNNANGAANTCCNANNCCAAACATCCNNNCGGNNACANNATNCNANCTANAAANTNTNNCTGTANCNTNNANGCGCANGANNTTAANCCNTNACCNNGNANNNNNNANNNANNCNNNTNTATGNGCNNGCTCNTAGGNNNNCCTGNAG
+
###"#$$!#!#"!!$#!#$!"$$"#""###!#$"$#$"##$#"!$"!""!$!#$"##$$$!$$!"!#$$#"!""#!#!$!$!"#$##"!#"#"#""!!$#!$$!!"!""#####"!"##"!$##"#""$##"##"$$"#$#!$#"!""#""$$"$$#!#"!"!#!#!#!#$!##!##"$!##"!"!###"$"!!!""##"#"#$#!#$$$#$!!$!"!#!"!!$#!$!!!##"$#"$""$!#"###$$"!#!""$"!""#"#$$#!$!##"""#$!$$#$#$#!$$$#!#!""#!!$#$######$##$!"#!"!$!$$!!$!"#!##!$"#$!###"#""#!""!$!"!###$"$$$$""!$"#""!!#"$""#!#!#$$#$!#"!$""""#!!"##"#"$$#$#!"$#!#"$!$!"###"$#!#!""$"!"!!$"$"#"#$#!!!!$"""##!#$$!$!#!"!#""$!#"#!#$$"$!!!!##"""#$$"!#"""$!!#$!"!!"##"$$!$!!!!!#!$#!"#"!"$!$#!!$$"$##!#$$"$$$$!$#!!$$$"""!###!""!!#"!$$!""!"!##$"!#$$!#!!##!#"!$#!#!$$####$"$###"#"""!$!"$!##!$$##"$"#$#"""#!"!"#"#"$"$!"$!!$$!$##!$!!$#"#$#!##$"!"#"$""#"$#$"!$"#!"!$#"""#!#!$"$#$!##!""#"!"#"""!#"$#!$"!#
@r270
AACCATNATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGNTAGATATTTATCCCTTGCGGTGANAGATTTAACGTATGANCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATC
+
E6B&H0>F3&(*&D85.B-E#5C!"%0?>(<CF2A'B@5.3CA<@&=E*5=E)A0B38CG/-9H<'"@0;#%.>B>1%':D0@0A#(>(G;2(E<==,:@'3B;0F@B-H3FF).45,G@?9$,%2,F-:9<;B134E@H;"G61)#:6&&+?#5#7EE&$=8#G=/0,-/(<BH"5,*9,9705)>
@r271
AAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTAGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACC
+
C86-1:620-"3;FG)052%-'2E..-5F<@;AE,=-";3>6#??G#!,HH.>F":B:):#58,(-;5$@#)/5F7.>7-G%=*%BCCF.'*H%#F'E%>;102(-A22)D-D,*68@="1*4C(EF*./G/85@?3!0*D83H$'"-'7%?046A')E>./A1<!')G=8@1B%'*@D3&B4E:A?,,?!/?5,;99<07@C&%)4'*A'/&;FA.'.*E;/C,$G4%$;8,2752F*608(:9#23:$+G3=::#0/6+>/38388
@r272
TACCCCAACCAACAGGGGATTTGCTGCTTTCCAGTGAGCCTGTTTGTCTGCGCGACGTTCGCG
+
5+B++FHF'="%,!4'C0,2534'7+4,36("+<)5)80C/1$6>;(8+**?E9C72=?45F<
@r273
ATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGNCGTAGCCAGACGGAACGATA
+
DGF4+$;803%&'7FA##5H2;BA:)=57;.GC?8C#B$'/&3%B:"7.H1?E!3;BG&8=<10%;23?1F0?<C9!=8.7):
@r274
TCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTNTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGAGAGCCACTCCGGCC
+
20;2E01:@?3@61%?$G0%FE</<+0.-E558$G7'G,8$1'><>4"6+;.D/:$/''8#2765HB",F;H((64&->9-E02*$:<+A?%$.7;/(&:!G3"/'H%E6?>HG5/5C6'9,2GF7-"G=F7(?H"DH#(C1<;?.B"!+C;6!.79=B"0"H<$.B7-<H2G-@0;</:38,4,#CG67>&064&>DA(%34D6@AB@:13,@7.*<:@#E+
@r275
CGTCAGACATCATATGCAGATACTCACCTGCATNCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCTAGTTAGCNATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCNTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGC
+
B,FE$H"?+,:ED!&&F/7D#$D<#(='>A99)C<"'>=#2$B.FA;*9=6365,0D-1@3+0'C>!F(!?&C#(?<3/8C*45B0E#(%576;71&?'@&4&2=.756$?@<D33BG26!DH4#7G5>,'?$2:!$2:B.D+F<-64>#?4=B<,."98??G4:2+E/D/%11*7'?$4.(3A638/*C*A*:%*,4)>+#=,4?/121:AC*'#2F2#.*=;F6GF=E7%.23:F'$>+*C.B&C1)39ECE=AF41>)411$*."?3642!#$&$HFCH@*2<"+"8.8C,H-7)'5(G5F8*<-0B6F.=<1E)*")50%H!F64"5$=(D+H%8%5/BA3B8D<.")H;;D$B:7F;%&"#"2>+#57=3&)1!9)?G54'6=09E572CG&GE&F>AG:+>'*$H($!="=/2(?F5E-'<D6)B&'5:2'H3+=,@=+%CA5)E>#.G<@?H54+$5B4BH10&(2FGG>('37(77$/6!D%?84;.+
@r276
GCNACTCACAGCACGGGATCGTGAAAGAAATCAAAGGCGCGGANACGTTCCTTTGGTC
+
(*!*'%'"!&!'(+*$*(%)"+!&"')!&$%$+")!)!%((!#(')+)#*&"&!#!++
@r277
NTGAGCAATTATTAAGCATTTCNCTATAACTTNTCGCTGGAACAGGTAG
+
"%$*)#%!!+$$#*(*''*#(###"#!%))("%#&((!*%!&$%($"+%
@r278
AATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTCACTC
+
66D66$EA,'!AA'6D"56(8DB#)!5@#8'.39B=(,"H";$?;00FCG;E4',?=895D@F(2@@"4,F92(%<CF03B>8!<)+!;")@@8@!
@r279
CATTAACATATTCAGGCCAGTTATCTGGGCTTAAAGGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCTAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGATACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCNTTACTACCGCAATCCACTATTTAAGNTNATATATGGAAGAAGAATTTGANGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATNAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAAAGNATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGANGGGAAATATGTCGATAAATGNGCAATACGAAC
+
+$%C2#/#*E!+&8&.5;*00#H%B<G6@="?>+<0259<3D@/H7C/*C)'EEH"H&<<A*B<0B2$<.(/B?%-1(4'(F%$"03A&%B?G#C)05E"',>4%+H"-G0@<B-"$7)+(-9>*;A)$D$19A3(&"H4'/.13/?"D54<!*,%C1&68+'.!G4F&9>4:1?B8:5FB:C%HD'@90#-'3%F;?%&@G319/B+-$..5;#<8)='5:G$655D511"2;=$E"&4&(E5,@2$3+'6@)-2D1#*G):E!:!:.,*1=?CB*?0=3(.D&2"/!,0"!$G3.&#22B:G-(/GCB4&"H)D&+,GF%8BDFD.C:8$<1=/G<A74@6.?H+'(99'>>#*%8,'"A=7+/(=BGH#,>/",%G#3F<>C-%*C5E4D4%#.--#@D#4G'2F&HA02>/$<!<7B.1+.<;2D:<=F,-;)90"*<8@.),440!H3B&-D7C&$8"F.D@246'E'0().#?)?D/1;
@r280
ACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTNCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCNATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCNTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTNCGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGANGTTCATCTGCTNTATGGGCAAGAGCTTTAGCCAGAATT
+
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
@r281
CATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATA
+
G">=1C90F.C":'F-5>)F.A":13*>E(H76+5C;)=G)#AEE37>*)HG901<@@G)/B"'7AA4BH1;A#<@8-11
@r282
ANCGAGATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGNGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCANGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCC
+
7B3?7!2?+*5!9<!7E:<->,5&4G7HA:"A6(,91H>63#$"2>=G'<(GG-;@826-=(6E$%7%-2?8/-4)$(9&&?@,D8+"@.6"?73=',GF&5,*&>F&!:#2G379>;$/$!-;?F@%0<$C,4)FG>B>E"11";;.15!!$F;/1>.7=5&49!,">702*$D%5"-5>?8">1&'5GB<;F=/6@*@:*0#/;"E9E<$5/EFA(.;@*=.D67E:??(!5%>%9(!-;>2)&C-)121AE+G-5:*@BH%F/?;%3-<#61;-"?%$.0A1%74,1D4E*8)*:5572H)BE)G6.+@;30>.05==E
@r283
TNGCNGGTNCAGTACTCATTCNTTTTAGACCTCTGAATCNATATCGNCCTGGTGGTGAGCGATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCNTGANACTCAACATCGNCATCAAACGCACGGGTAATGGATTNTTTGCTGGCCACGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAA
+
%'$&%"(*#++&*'&"(&'%)"+#%#+%+($$&'*&+%#"&"&!)#&"$('#%!(*!'"$%!"!&#%$$&!'")$"*%*''&)#"(!+(%"#"(#%*%$'&%$(+*+("%'"+"#$##'#$$"!$(""&%!*#$$*+**+++$+"!%())%*(*)%"+$%*%##'**"!#("%'!"*%+)(!#)*&&%#+$'+$#+%'$"%()'%!"*!#*#*#*+&$((()")#)"$!"+%&!!)*(+***($))!*%*!!#*%)#)%$)%&"$+*$&+#'#$$&*!+$%$*""*(%"$'%'++*'"+%"!$%')&&*&%%!*!!+(("((*+%(*$%+$)&'"%%
@r284
CGCGGATGGAGTAAAAGAGATGAGCTATTACGAAAAAATTGATGGCAGCA
+
/:1@@D--HGC=(-9#&8!>%!)A8'!*;D6HF@@E2!-2,@-95FD,4"
@r285
GNATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGNCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATANCGAT
+
$#'+#))*&"#*('%%$!)*%!"%#)#**!($)'#""+*(!**$!""+&$*$##&('*)*)('*$"('$#&(%$$'&!&%'&')!()%$%(!&$*('#$+")*"+'&$"(!#"*!!#')()'(')'&#')'+""+('(!&)'#%+$!("*"$&
@r286
TCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGANCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCANTACTACTGGGGAATGAGTNGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGAAAAAAAGCAGAGAGCAAAGGTGNATGCAGATGAACCTCTGGTTCATCGAATNAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATTGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGANTCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATNCAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAG
+
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
@r287
NANTNNNGANGNTTTNCNCANANGGCANNTANCNNCNNANACGNGCGNAGTCNTNNNGANTTNNCCNTNNNNGCGGTNGCGTNGNNNNCNNN
+
!#!#####!"#""#!$"!#!$$!"#!$""!!""###"!$##$##"$!"""!#!#!##""!!!$"#$!!#"!$$##!$!!$#$##!!"##"#"
@r288
NGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTCCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGGCAAGGATGAAGCCGAGCGCATTGTCGAAAAAACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGANACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCCCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCNTGAAACAGAAAGCCGCAGAGCANAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGNACCGGGATCGATGTNAGAGCTGTCNAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGCAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGNGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGNCCTTGAACTGAAATGCCCNTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTNTGCCAACTATGACCCGCGTATGAAGCGTGAAAGCCTNCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACNATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAANCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATNTTCTGTTGAGTTAAGAACGAGTATGGAGATGGCACATAGNCTTGCNCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGATAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCNGGCCAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGAATAAAAACGTCGATGACATTTGCCGTAGCGTACTGNAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCGCACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAANGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGNCTCCTTTTTTATTATTCCCATTCACCCTCAAGCNTATTAACCAACAGTTCAGGGATTAATG
+
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
@r289
CGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCA
+
2G4?0?!>F3.E7*9,(*%-:"-+HCD,3%-5A-,C-D%'70FD=HHA:&"/3?=#:G1D("?F1'D+5HH@8-/-/**74.1!*=0@,00)&(#0G$%(;DC-67472(7&>;+7(*)>9?@A&'70)C,")>!",=+
@r290
TCATTTGCAGCTTTAGCATCAGCTAACTCCTTCATGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGNAGACGA
+
%#*'(&$%$+#+#(!!"'+)**%&%+"&'#!*!$$+#&#"*+))+)%'"%$#%"!)++%"($($+)%#(!%)&%%"(+*($(#"+**+(#)#'++(&('(*)#+$*+#!$**)))&(+#!+*$!#)($!*)#*%*"%!(%+#"$%%)!*(%+*'#%(#!%*)&%%!($%)&"!!"#**&))"&$#("&%+#"!
@r291
ACTAACGTCAGAAAAGAGAGCATTTACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGNTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTNCCTCAATTGCT
+
5:73<<%=A@*/D!B7!C!497,)1?58-/1=C:#)&!91$*4'A%6&!B6$",)F1CDCH4&@-AA27F-A8"32+:H?-!62$,4%@+*E('"41<?C<E1'0:/G'7;$.?)**=5E9%'B#B!@/75B?68+7?*07?G>?FFH0.FB'/6/A,"(,!48'HF.=$!2?+<9C:H2.=G&=>18>*;;@E".%,G-#)<9;4F.?D0BB"+",G?-B"+2G$2?$9/9!>.FB3:9D)G./8B+<;F>4C/278G/$++.H:5%=)AC,D;E*D3?<5"
@r292
TTATCTTACTGTCTTTGATGAGCATGGTGAAAAATNCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGNAATGTTTTTTTACTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAA
+
;4%3D+&GC):-,8=#<'!A)3G1!G3(0AB1&"/:)/8:"":?+-A;3+0@9@1EF;!(5'7?<@@-/D?B=E=?<=#)-.5;&&?>,>,$A&%7>BA$H&2(?#",(%H2;=1&<&2C/>/+>20E&7-(.8$B#;:C#7,"$6E:*(3G8@6:C+,26"B/0)E)51009-2(##D0A*DD5FHC5AH3?941B4<&#630,
@r293
NCGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATCCACCTCACGGATGTAGTCGCTGCCCATCGNATTCATGATGGCCCGCTGAGAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCNGATTCTTTCGGGAGATAG
+
%4?#>3FD*E9*).)0!%31,"B0;C12''&-9CD(&)5C:2,+D7!@;(GA>@D+6>@+."-681F9G<>CF4'"&8@#&,H$,8..-(*1$FF25E86-%E??8E54;%C%FG:4<2/9D!93CA76C!5386A.B@9@73;,3<7)B0BBAG"3F+958.F1/2C9-<,/"'/2)F2"-99B=2+!8'D<?E*>/D+7A9:9"%!-'#E(7/+>$E5.E#!/&C'/+5"3&#'6)?;9)#E>-0)@"C*H0</%42E9A$E#9B&G
@r294
GCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAAC
+
15;'B:.9"G"65@?2?58&%.%D*>D9#=7-<5'A5"4#01$B83162)H:=BH
@r295
ATNGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATANCAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGANAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAA
+
4B.<-F*5B->#'73@!!=4GD$H&@?5%E$58:G3)HB"22:90.<*G::2$.1((9(D0/:&E1@%(F(-)G?07.-6-(<.'2(G2AH@!5+2+>//<(#$?<9F2D,8.'%@HE/(4*46+(8*DEADG08)?.BB+)$4G+<7/)FFC0&98:3/-G0'D9=66A0&9$8:52E9D"&!>/:,A80!%-H#$%6CH<B+%(,=5;&:8C-(>-7F%';GB-/&G)3C:&)%H%*&";<B4"+&8:;D/A
@r296
TGTGATTAATGCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATNGCCAACTACCCAAATATTTCGGAATTGCTGCCATCAATTTTNTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATNATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGNCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCNCTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTC
+
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
@r297
CTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAA
+
3&3);!(+:,/0?5A/4./787)AG&0-+=(83.0&9)(@(5G:7.,
@r298
GAGAGTGAGCTGGATACGCAGTCAGCGATGAATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCNGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAANAGTACCGCACCTGATGCCGGGTGACTCGCTGAACCTGCAGACGNCTCGGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCGCGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTC
+
8"&:C/%CC:9"0+D0?$0$>=E-3$+@3-AA8D,=%2562ABE65/:DG"&)$H$?,,%FB32F->7-C.!@&/B:4!+#(6.#3;08*$1)1HB:$*FG*6/(/D;63)B7;(9>;).5<&=#;58;9:>F94B1/*=2"">9B179".8<+4;==%/6,!:.B,/E&>;80B54G$5G0;#$0H&H+1/#>G+%3E?>A""0);/D7""/H4@)A0E661G.:C8&A,,78",4AAG"A'1.F5.@?3!D<5<*8/(C;/!<8H/.%-"'H489&HH9@#GA-D:G4E1B"A'96BFD873BCHE5G<>@,&B',(2'#(561H8$1A*7*>*./,7?2-#D:<$.;*'H;E<!,2(6"''/5:;*G':>
@r299
AACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCAGCTGCAGGNTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTNAGAAGATAANTCGNTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGAAGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACNCCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGA
+
D-&*<?)G=CB.:##E8G@>F;=()4+&F&;7$@":-3BC7)-<&6HAD=<0+4%#%@?;CC+*"#5<2*4*/8D,E(<8%->%B),1:B>!B0"=,,7F#DF05:/>'8$,9%6HAH&G6?&%5)6@G+,""-;0?=%G>"-'AG(%B=>44HF%H#BGA1'$G26G#7#@$EB-<=G<H,3;82AA>1!!?9$.H;'3F0%H18,E.$>5;7.29.6'!@6'";(!"=G=C$C73"2#&"4H+G8)9,E="E#2H+.%#E,FGB?.$"H'F0>1!FED"%9%,<$=1>8@5"'6CA6B8:5)HG)D,E'1+$(C?$/833!0?2F%F3-3EBD(>"$-0'B-:?'>2>@,.>@)'C?%3=6H4#+87,>.=(B>#*0@8/%+*66!;4?A/:H0'G3(+F%&(G&3DG1@,*2=+=AF#8+%B
@r300
CCGGGGCACGTTTTTNGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTG
+
(G%(*):,#>7DG55(.*7/A)2.??CC63*'"<50AH8GC?6B**/,A:?4@78:CD,<1)"8C3;<2H?(.3=(@39>$>58?EAD";C)&<7-:C8'4<>(%,H6.$4C%F:2CE/*;!F:<:#EA#&15-BBHD>GC08%(D#"%/3%363*><=11,&9F*$9$8,,?5:8+<#E3
@r301
TTATTTTCATNAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGCTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTACTTTCTGCAAAAAAGTGGGGAAGTGAGTAATCAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTGCTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATNATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGGANTTGACACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCNGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGNA
+
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
@r302
TGTGGCTGGCCGTCAGGTACCCGTACTCTCACCGTGACCGATGACCATCCTTTTGATCGCCAGACAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGG
+
*(C3")993HF(?'!6)')>5'0:(H,>;+F$*4<922:/1-E1'8&<7-'#$164C7@DEC"GA6)2(@:C)"7-51F4C$!,4>+/;,5@%5.16E>G%D%$+EF7B,,<H*.5#-D3,<-./G.G)EFG;:>:A;C+G5;@!<;(6*;D8,8)';;.2'+
@r303
CCGGGATCGGCGTTTCGTGTCTCTGCCGNTGTGGCAGCCGAA
+
;FG;E%B2&%B./B,-1H9':>7F.',)!/5+=&"''H#GB@
@r304
ACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCGGCGTGAGTATTACGAAGGTGTTNTCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCG
+
(!H:H90?+<+@,0G00@<F!'F)8"*B$-!/)/,"$,AF36B"H;=!F=38H+3/4)/%!*F9B(7*77:G&%?=&2'D1A0;4$#*=('3/AG2CE'7$76,F8-@,%3'%G*7?!%#?63'(6;D=7><H3+225&A"4%#+>=@-G3=+,:)'-?#%
@r305
NTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGNTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCANAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACC
+
$++($(()!%*#%"'$%!%*+&%'&()*%'!%(!'#&#*+#+!&"()%&'+!!'*#!#'&$&%#%+%"!*("*!)!'*'!""(&$!'**$+*(#$*"&(%#!%*&+++&''%(&(#&"'#&#$)$)%)"**#(""&+%)'!#+!&****&
@r306
TNTCTNNNGCGGTGTTGACATAAATACCACTGGCGATGATACTGAGCACATCAGCAGGACGCACTGACCACCATNAAGGTGACGCTCTTAAAAATTAAGCCCGGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTNCAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCCGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCAC
+
&*)%$#*"'&+#+#)+$(!$%%&!!$#&+#*&(&!&!(*+'"&*&$$#'"()+##*&))%!##)(!'#!+!'($&&*&+!*"$'"'%*)%%&""'&*!)'!*#&**#"&#$"#%()*&&"&#(*(!!&')%*($'#*("**%)(*&#$*(#)+$&++*$#$!(&(##!)!$#+)!"%'$%('(+$)(#)!#%#%!+#(*'(%)%!%+$)*'&((%)!)""#!')+**#*)++&$&++(+(&'(#+("$)!$')#'!(+""#!(##++&*+&$"&(!)+)!'())&&*%'$#'&*")+*%'!!)%!%(!(&"#&&(!*!##"$!%*+#+)"($$)(%(%#+%)))"($"'"%!$'*)+*($!#$"(("+!)+%#$$$)"$())'$%(&(+#%"(&)'%!))(!'#*&&%)!
@r307
CGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGC
+
H5E;6H&26;*30*@H?AD&<F<97-1$$6?%7A0A,A&?"=C@)./-7?32
@r308
ATAATNGCATGAGTTGCCCATCGATATNGGCAACTCTATCTGCACTGCTCATTAA
+
#)')))*)''+&"$$"+$+'*&$%(%()!*&"*&#''!#)**(""#*($)#!!*&
@r309
TNNNAATCTTCGCGTCCGTGAGCCTCCTCACAGTTAAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCNGCGCGTTCACGTCCGNCTGCGCCNCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTNAGTCTCNTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGGCGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACGTGCACGGACAGGCCGGTATATGCCGNCACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCNCCCGGACGTCATCCGGAAGATGNCTGTAGGGGTTGCCATCCACCTTATGGCTGCNGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCANGACGCCGATGGAGCCTGTCCGGGCGGTCTNCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGNGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGNCGT
+
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
@r310
TCTGAATTNACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGCACCCGGCTTNCCGCCGCCGTCGCATCATCA
+
F*H;/3#FG';!)9GC3D&+D!C%!E&G$G7FD&%5&(20'E?$:H)CE?(8!)$9=&H6%7$?C-':1.',2,DDEEBFF=;$A52<DE<)6",:9A*/C?+2CG,?(*@(F47+<G,>%+;+8:9
@r311
CCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATNGCATACGTGCCGTCGCCNTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGATTCAGCTCCCATACNCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTGGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCTTCANCCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATNGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGNCTGCGTATCTNCAACAAGCTCTGTCGCCGTCTCCCTGCCGTTNTTCGGGTCAATCCAGTTCACCTCAACGGCGTTATGGCGGTCCTTCAGGGCGCTGAAGCNGTAGCGGAACGGCGCGCCNTCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATNGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCANGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGTCGTNGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTT
+
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
@r312
GCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTNCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTAAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACA
+
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
@r313
GCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGA
+
F"&?G!E':"G;#)++,-A28F,$/(/')#654GE676%&4(2&<=98=#8F."!7>F)@.F*6+0$=/EB>3C=3>:?B)=#D);7)1"4759-188-;/),28#?>:D6,BB'1;B$!=4#H,.9CF#?2A88F=-(%9%..!=6?'!.0E.88,#FE',"0?"1/$,9)!'3,6/?,EA45476>/9FG1=9?@<?546<+F/-;-(-:838D4A69<DBGC.8'1!A2G(;348(95*)D71$<0F-D?*'<29(&:85$D5B-<-AE9#6&H?F0D-8'?G4(,@8/+9E34A+(=)7&=/8%%<:##=C))8
@r314
NNNTGCCGCNTTCGGNCGCATCAGTTCTCTGGCATTTTTGTCGNGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACANCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATTCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGNCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATNTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCG
+
!&$$')%$(&))*)!!%)$(+#*(#'$$)%&!%)$))'*#!('*$+*#'*!!+"+'")&&'%!$*#%*(!%*%'$+#&$*+'**$%*)""#$""&$(#+**((!$%&+%#&!%!+!%""%&"&)(!$'%%"(+$"+%&%*$"$$#*"*$+$'+)%%$$+'()(&)'((#%!&&*%+#(#$!'+&)''+))%!%$((+#$&$'"%&*)!%*"!")#'#&((%)()"%%('$(')#+"'"%%!#'+&)!'#+"'&!&'+*&"$$(&#%&#$'*"&('%%"$##"$"&*(&**%(%(%!%!'+$*#&!&+*+!$!%"&('+*$!(&+%!'!&%%#&#%$#***#!*'%##""#'$+'#!$)"'!'+!%(&"!+#$!''*!*$#)&&*"#'%$"$*$'%"&#)(*+**'#"#'##!&%$'(&+#%%&'&'$%*!&+$&*#""%(!!&'"$#'+&("!%'!"!"+"'&(+*'+"&'!&)'!$&%"+!$'&")#&*&'+($)(+''!!')!%*&'##$""'"&&"$&*+'#*!()$$&%*!)+('(%*+("&))')&%"+(+!&)($++*&*+'"$((#%"*$""$*$%%##'(+&%(#"!)&"!$)'+"$&"%*(+#*%*#&'!$+$(%'()+$)&")&"$(&#')&++!+$+')%'*#)+*
@r315
TNTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGANTGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTANGGTATGGTCACCGGGATGGCGGAAAATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTGAGGTTTACGCCCGTTTTCTGGATGCGGTGAACT
+
.75*A=B07F!D=@<!A;>!-H1>@#?(#<8/4?4AG?#D0(##!/&3/H4H.2HFG+20:&G(#8C:):5<'A:&EB38-(&>$'&98@B-*<$&4FG$*>EA:@,7F.'7=.8/6<+<F+0;17F>'=>D)3)2-5%$782,60!%.<B*&%EF'E87!:2!-)?H6F!9C&(+?@D/@%AGC5A3"!$G')D/!"?;5FH0HG;B0:72.F:8E.+.D:'):<C4)(*%H7+#7/9C/>1
@r316
NGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGGTATCTTCCTTCTCNAAGACTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTCCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATT
+
!5G$BH<&D*6C"3&(46G-+;/D(C9532&=A*7'1+=3/,3(H+%5,&6F?3+(*HF-9;#(&4)%&,,>7=E*5C-DHB@7:--:&E$&4A4G*++AB=/:=06-6E/(BB(E>:""$@HH,5#D:A$>:.<#F?24&CG,$A?H(8AH$>4*)%/9(1A+"+>(71"9>6/=&*@??9FC
@r317
AGCGCAGCAACNTCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGT
+
:,-8>)FF".1>;),')#2-*5GH;470$<)A7E2,94:E##+:!49@8H$H.;%<:$!?H1,6CCH$F3*2<3@@%,A@E%,#E"9
@r318
AGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTGGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCNTCAAAGGGATAATCGGCGTGGCAGATAACATATTTNTTATCTTTGCTCACCAGTTCGATGATTAACGGNAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTACAGAACCAGCCACCGGCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTNCAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCNGCACCACGATCAACCAAATCGCCCACTGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGNATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGNATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTNCATTTCAGTCTGCGTNCTACTTCTNTTTGATTTCCGTATGNTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGNACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATNTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGCGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCNCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTTCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGATTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGGATCGAGCTATTCGGTCGCTCACCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTNAGCCGTGNAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGAATGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTNTTCGCAGATTATGTCGGTGAT
+
";40"5!C;92+0-$)B13!47:H'7H$"%#$B8"D<!&$5F=6+3$83D%G0C+(+=%!/-$5.*;)($0A=(9*?7D1&/)B,-6+1#:53!6A'*!+DE6"4H/G">,D:#3'#AH%"D-00#9%B+390.7(9(FGH*&$'E-+9:)6'!C7?CCE:9E)@&=%(#3G8!<#'H)AFFA6C8":"D'"6>@<*4#678@*(7)2:);:%=&H@1'!$%!A8&"$@+G5=)/3;G-0C>)@-H#";F)*D.B+4/1%;3!-%A5"<="!7//>&*DA.98E:1022#F9=0%;?"A*>&C'AB/C?GEA/!%5<%$&%63C('9HAAD2,3=7'%G!(<)=.*C!$)E.$!-#%E!(2-38703.77H2<D.@?'/1E#B)/9/.0%85##=:>/9&2!C?+8!<:F2!&0>!*EC&GB.A'7@"91;)<?*0G=:!712:0:+*/.F/9&+G'G@26=/2>9"?>("!8<'3+2B>'#;75'9=!+D-&7A,5:#+@<D,;6(H.:;/,:BEE6;7@6GBG'02:#DF4+036)B6E9!+<160+51&&E#;(F79*F'=E<>H=E9C4G1@13%;1-A>7*=H)07%'B57G-:C3:*,>4&&.,G(4'F&8;"0$>=)"02'!%;-!E#$6@542'#";<6<D#9(#!":(A'1HCC?D5.((@;!E'GB="?<(#!4FB'?@./:/?#3047&C$#*$B440#'H%#/44B7>G7A2-#,3%EB;--/."=.(91BFDG5A:9,8==F&A&"1;H.*6%(CG'ED4BB5DAF$A.B&&C*0C:A/7F>)E*)++-+-$+@B(F=*F!5C1$>BBE&?%(>%..&B8+--*F@=@/E0A-&8F3&$BC$+8043>;A>+2!@>42CE8#*CG!&*''D#;0@/:,>1;9"A"FHB)$F&1)%0D-A0)640%<,-=#?%0<!&<C-)E4(*4F8-ABF<3$+CC=D-+#2@@2;/448!,0'(:G9(:GG&)70/,5?A(3?CD%(1A3:0?:CB#?0F,'B+$8H,&4'8")'3@/=9<2:'<)G4,=7<)>#.3,&.B75806/(8%(<",7'-A53D+//6E:2%#5,=-.G,E'6$*0A2<-0G,;1%=C2C)H:9H=E>D1(B@#%3;F%<1-HC;!:(G/242AH?51H)'@+?1=89+A,@1/&1%?'6>?65:6?F8"+H=!)H>)$<':;"3)4F/:>:"$H.=*4+',58<"1/.)6$>+&,,/AC":?FC(4F'=%?+1C#F920-C;>)6F1D4'89/#,,(852'$9(GA2@+:F.84@A)HD>*D8(35/=4"'-,9D44<GG7+&7;=;7B&741:(C06A20B;B37@DBB.2*(+C>B1<#%>8DH>H07->*9-7?D.&',)0819=!<61@)''9G-FF+'=&9!)!6+B9HA@3H313F'B?@7!.2C@"?!#0?001=7GE6(2=A,+9'/@"/AC;(F;0:%6->H'4H29*<&42@7<4:)@EA!9?G>>%D:*>B;.677-/*D.)B%6#>D.5@HE$*CH583:'E!?+'@6G3:)12(-B).C$26?'?-C.B$21&G2&84H$,9H>=@2EH%.!542*"-+#!%+?A6*>3E?EF'9*0A:-<@/*1)-F7&:>1=ED#5GA?259G*GH&6+?F8F9AH'CAH::4=@,35::>D59-F*.;
@r319
CGGAAGCNAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCG
+
,-G*1D*?G$075@2C?,-27A2$)?(<0;!-A5'@&.205A?'%4C'>/9<5=9=<C62?'.$F"G6=20A42*&<-*6C!),,-A*,2):49A*A%'#F?>(G@/,C>EE0?E;.72.!GF>>%4H31<A@,B=(.EE%#FA2H&773=)(7/3*H63"F%%HDH)C4+!CD'"@-0-36-C+/91A'#0"E,$66"8=':<7=),%0&C#9.8$
@r320
GGCGCTCTCTTCCCACTCACTCCAGCCGGACTTNAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCNGATTATNGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAAGTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCNCCTGATACGTAACCTTGNCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTANGCGCCAGCANGCATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGTCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCCCTGTCTCCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCANGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTCCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTNGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGAGCTTCATCGTTAACAAAATAATCATNCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGCTTTGAATGCCCGCGCAGTCCGGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCCCTTTCAGGCGGCGGGTCCGGTCATCAAACCCTTACGTTGCGGCCTCGTTCGCCGGCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAANTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTG
+
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
@r321
TCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGNATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTNCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCCCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACNGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTCCCGCCATCCCNGTGACCANACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCANAACCGCTCCCGTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCT
+
E&E@9C$C&>+=;7B'0=3$3<#20F=&H,)66BH772:<&D+@D-),>+G6A9E?<.0D%+E.!C'?/)'B@&#D6=B3!"ED9><.9886304054-5*C8"%%4'*6-9BF)(*3<-<?%&-C,B&FH=,HAB#!$*#E-$7!A-93C;DG!6'.-8&9;=0H12'=7#@F71.2=)1&G'=D6*;*93@='&.9BC-'FH"E##$A66F05F*.0E9-B)H9G:FB@&$?2HA&C:?8$=A@(/0565<=#@9-8)%4+B-!D5H9.8'F/11@H10#'>/2C79@H!%*/;'#EG.'B@#1@',9;5&-."2*29C-"!C.%/05:&+/@H*/=@&C&ABA?*A>&'=AE$&6"<"&".%!0!4&&;A"$@</'3G.H!-)9D$"/>8H%$116@5>@FBB47=)C@0#<G=8-*306+/*4G0%1+!;08(%3+=>G(%-3737$'*5!0,4@:=:3!:E,.,?B(+5?(F5591.(>
@r322
TGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGANGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATNAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGNCAGNACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCAGGACGAAANATGAACT
+
C7/)7#G/0!2="%F0&>/8'>$.,A,*=;&5!'D"32;E6-2C%!60=+>+/'5"E58-%::(9&G9H$E023%.3@/+4@-1.3$(!5C>D?A(0+97!$'$F@64@/C%7"*F0@D!(:/FFB,=2F)"2G,%2%F6H1125.G+)%G"#EFGD6,E7D<H(64$./C*F1"!F=-@2F-2;/0%(">;-:)B'A'CF0&"F4%.2-*,D*:GB?(;%99-C'3!DC@#D!))16,0-++,H1:;A+850B>(>@'D&3B@D*+10!6*6<<#3;1$%#@F4>FH'A)/2:<DB961$%0"8(0?D'*0,#@'?89A49%()+170!>H2<H<39/&7:4D*,'$,48'G6FA!*D5H.5,60C?6'C/,GB9)96C+A56@!>?/G3.*<C%H;'2@?58-HA%2E!9/)1%5>.
@r323
CTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATAC
+
1;CA00>B"F;E;1*H"5'"3$7DD91#;'#8GA:4A0)/-E;B'A3($4:-=C"%8!8:4B1(1!D51*<5'/9/98*=6,A67/C"95C)E:3##D-?=5@?$BE"!*;G58.A#75*!A'%",GD5$83!464D*+DE:@:."2F:$AH*.F:D-><8':
@r324
AGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCNAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGNATTACGCCGCAGCGCTGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATCACGGCTACTCCNTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGNCGGCCTGGGTGTCTCGTATGAGCAGCATT
+
@<567,@+#A5167F;7,38B8B6'G.-/!@C/850,#$=*);(F!/B@,C!:6'=@%<;>?:<2&2@<,9E*/E(6=F(),D(D'82H$!?";E*3:>7.)=8,8#0B,17A4G$*5!7-03622-8@(;;'>B."*#0%2*BFEB6&<&4F,0H8*<7;B4#$$%6.G1313H.DF'7)#BAB<9$6"'=?<$9<:E'C&>:3::5=G-FG+H:-'9-"B.C,,8:4&54%@%8>452+DBB#1-<'F"$G-08-,07'*"D'<5DGEB<9?3>)%HD>*$?@3"8G-6,/#(.CH=C%.'C3+7(6H+HF..735:?>D%684+'F"=>E:0;$($#:765D*5''C&
@r325
GGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGC
+
1/25',1F>':6/"86G1*"?=?>C>B<<4?'!H%2?0G=="84$E=/3)@D;E*43*/129+A28.<B89*?4+6@F5-'9)05$7<6'(:
@r326
TTACCTTCCCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCG
+
-AB!3";-)/81(9AF,69ED'=G"".#'6>>"78D:<#D0!.&"4'??+#/:G,!0F>G&?@2#,+2;*D0)#%.B+9!"-9/E8&A36*3/G67<:"5EGGC@(D+-/,7$'*-3;.C%6C3"6>,AA-GH@861(=
@r327
GCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCA
+
0D>7<?.;/1/+<F9%7-/@,D&D8+4''!<?67(.FB-%:"7;
@r328
GTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACNTACGCAATCTGCTCCGCCGACACGTTANGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTNAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCAGACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCAC
+
4+;;;9==<2D$"/8A!&>(A#?2,<$.")9<'>:((?3D>=G3(:@&%((!H(3D3--!1E"'G$,G1'7-!$:5D8-H*9$=*G"C"-2(95"E32)B)7(E+,?(*=6-=7:?5:A7*/"/HC+8#$DH?1*54/12#+?E;*=2E),>(3-1:(.>3/2"9:$/)"(.%.*G#E,%$?=3796?3,<',.@%;+#*)C18,BD@%1H>%%6!-E-,B=)60<E5F:".=;$.@0FE/<6.#/#,9)*5(+,3H405/C*2DD?>,&6"+7.6+8B3H?+E*3A(6E*.,4/E!/)1'9.:.G<F'46F;785H585<$=7"8(#DE"@=*;.E&0B=$,B$F,-4&619?;=&!&2C+H-.$&D5)E;69;3610)3>7D:$C$<#0("@+;>0;H7#H67-'2*#6A/=H0*/="+6$6)D7A%F<8!);F8,&!*(26:H?B.=
@r329
ANNCCTGTGTGCNTCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACNCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATT
+
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
@r330
ATGACAGGANGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGNAACCAGCCAGTAGTGCGCG
+
4C,28#$'6)*/"0$F$A4>(,D>?!"&'&;38F)$6&)6*@3EGG58)A$,;60//)/*=+2!20E(>F*,0=@:45=8A=D7;3G>E'9!*H(:A(=39&)F!(:>90:*:E$,'85>7G?,>F(<.8G#;-'AD&+,0@**H1GB:*EFA#%D<H<F26
@r331
NATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGA
+
!/=A<9GB?&E78(D20%E-;;-&"30>$+4+-D>76>:85?;:4?6"(>;">B(B##.>',03/B=B)?FD;"#<-7%DG)C$"6;91;%."-C%--+!)D0@#A5G66)+34-;:*%@7<,7#1/766!$:'?FG=3$0327F&>#7&F/!(5B()--2H39+E>HGH!99@9=*"846'A;6?:/B$$;64+87&.5
@r332
GTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTNCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATTAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTANTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCNGGTTGAATGGCATGGTCGCTGGCTGTATGCAGAAAGCTGGAAGTGTGTGTTTACCGCA
+
?0?!)<10A%7)!G'3"9'7"-3290(8444FB.(.;&%*A.<<7/?E>C(04B0%'>>.A%?0H.F3B==.+7*-"D#4"/'$G8;#!378;?@*5+/*3)*GGF6A:@A73#13(&?GH<%H(G>);;C";$7H*1AG3+?!:@9+42H!"<G53*5%8'.7E,41:/&@(-FA%>D9!C@,(B%2@&1&D6;:)F/#%;30&H/;5%;D2H>>/1<D!(&7G43>?,642G&,E4E3317;*-@44@3,+@;/"-F?D,5,2(/309D>?F-D;3)D:07?6F2/(?H8(5C7D83>!%2E("%($-=D-C#'C@/"=%-9'?=?9AC#G.C4F.9:(?4%F&A)0!3B;5B*HE*=(4
@r333
TTGCATAATCTTTNAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATNTTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGGACTNGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGNGATGCGGNGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTG
+
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
@r334
CTTTTATGTTCATGGATATTTGTAACGCATCGGGAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCNTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCGAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAA
+
,6%B&3."-8>7,43@9H1/)7-;(4C;!$%3D6B3%H"&$65'/00;>"A7'A#D!6('>$/C89-3+/C0=6'3+7>!;2?@$.G;9.4=0&$#2AEH(':E"B8"+@3D8.D9>!C>8+?="A9#>0421C/0474(526/2:H=HE(#G;3%@C"HG)7@)AF2G:G,:202-1$5&<9+F<HD)G<FB<-/,@G836GFD'=G!>-.G4+4=<"48(,A&-;F;A0%,9G1A,D2<A(56;9FDH;G")G,<BA,+4#.?+,B?C?5>6A9B$%;D+%B:7DF#!#$CA'C3@==D2/3F/,DG)1A!-+?'.H*.!$)<(:/*#A%BH=.99HF1
@r335
GCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCNACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACNACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATNTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTAGGGAGAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCNAAATCGGTACGGATACCGCGAAAGANCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCNGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGNATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTNATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATCTCCACCTCAACCGGATCGAAGGCTTCACCG
+
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
@r336
GAACAGACAGAGGACGCCGGGCCCGCAGNGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCC
+
#%4<#0CHB#45>4D-E)*.*?&/C=69?F8A7B*@;*<(.&C7,#=223@BA22#)B/-;H7*=F)(#8$(A"7E34"*2$1:B4FE3(D-<C+6.BF3-(#77:/G2;11D1,=
@r337
CGTAGGAANGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACANATAGTAACCATTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTNAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATNGTCTATTAATGCATATATAGTATCGCCGAACGATNAGCTCTTCAGGCTTCTGACGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACNGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAATAGANGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTATTGGTTATGCAGGTCGTAGTGGGTGGCCCACATAGCTTTGCACTG
+
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
@r338
AGGTCGAACCGTTTTAAAAGCGATNATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACT
+
1'C-1+@66'7.>A6#<8FF..CG#":.76"$?.E59!5/7.#F6"!D3/-%-E0<"#C.**('/0,*==@5AE0H67:G%(<B!1=::%4&7*&"-F"'B#<2<4DF7D3>.!=%EF-8@,;@"B3:$/$939;C/0=!H&2)1)H3(#D0?-%??
@r339
ATNCNNGTTTACCTCCCGGGATTTCGTGAAGTTCCNGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCACGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCG
+
)$#%*(+(%($+"*(')#('!+()&*("($"%"**$!%!!'+)#+'"!+&"!"+(('%'&''&$#&%$)&)$+)*$!($(*)$)$)('*$&#*'!**)"++!"'+**)&''#"'+)+&$$''%*(*&(%#%##)!"('%&!*$&%#))!!%!+#)')!%))()((+*(!#$)(")#"!$"!+*+&#&&!%*##$
@r340
CATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGANCGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCG
+
4H=AE4+"$/:;+6?)462"*1A-775-B"49/:-2..E.=B5F*/!:44D6#.,6+"<6E9>@+D1*'0+,01'7F#0554/A':AGG6,$8&0$0,:D+9!37.$)-&)?//CD6&C,">7D:9-+21-0*0(6$='!9DF+B,=%7?-5$@72F*5!%,=?H@?9@<<(H@7B:1.<2)@8$'.1(7F"=5:&>FH<D:#-9%=,2&B=>7E&1E'16/C+A2!&=796G'<F>=BC1==<=4:!9!$
@r341
GTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCCGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCNGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTTCCGTCTTTCAGTGCCTTGTTAAGTTCTTCCTGACGGGCGGTATNTTTCTCCAACGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCCTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTGCAAGCGCAAGACGGGCCTTTTCACGATCATCC
+
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
@r342
TGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTGCGCCACTNCATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACGATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGNCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTTTTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTNAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCANTTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATAGAAAAAACGTACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAGTTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAG
+
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
@r343
AATATCTTTTATGNTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTT
+
<56D8$B45%<>B)G84AA<4.CA<7/0%+7&+BB*)BG61-AGE'0GE&!9&;8#2">G,;762&4(0*,5',B0E=3'1!8*@6&;C9&:
@r344
NGAGTGATTGCAGCGTGTNTTTAATGAGGTCATCACGGGATNCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGNTTATGTACCGAGGAAGAATGTCGCNGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGNTCTGAGTCATGCGNNATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATANCCGCTTCCGACCAAATCGACCTTACTNGAATCGATGGTGTCTCCGGTGTGAAANAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGCGACAGCGACGAAGTATCACNGACATNATCTGCGAAAACTGCNAATACCTTCCAG
+
"%(##+#&$*'$%")")*$++#)'!+*"&!"&+"*(('((&!"#"&*++(#$*$!"((!'$#%#&(!*&!(+%*"!$!&*+)#'*#(("!%*''**&$)%$"*("($!$&!%+$%'('"'+"*"*%)((%$+)&&*!*!+!%"!##'$*('''&"+%%*"+'"$#%&)'*"#+)")++(!#)!'*%(!%#&*(+#&&(('!"!&!)*"("#'#+"*&($)&&''*%!*!*'$(!"!!)"%*%+'(')%'))'"&%)%')*'%')))(&%##+&((&+)%#&+*+)&)'%*#*&*!""&+**!$$&$&'"$!+"$(#&'%!($)&(+("$&+(*#+$*)%!#'!&+##"%""+$&!%*$!%+%"(+&$$"("+$*&)&+"+*++(+$%(!'""++#"'"!&($$#!#$!%+")#!$+#&#&#+#$)+"%(#""##$%"'#&!++$$+*'$('+%!*
@r345
TTTCCGGGACGTATCATGCTGGCNAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTACGCAATAACGTCGGCA
+
.G)/H)-::"#(18C"2;92@!<E:9&"1"%?(4+C!!5B*)E+!@-!H0B0;.,("754:"!<:3#"6(&5+7%0/6#,B!?<)B@!%?"-)?)9H%!';:6B:9#A5#157A87")->8H*7E3F:/(!#F52"C1&64&@D86=9*F=!->@B#0>>9960):?74:BE
@r346
TTTCTTGAGTCCAATATNAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAA
+
):%334!*#0@1.#1#7G<FC"65#+7A!.+/*'E3"!H>42-&11$#@/,&7;*2G;A/H+2>/!=:'!*,HBA<0,?@;<H?=:$.G6HF5"H*)(EE:=*E=#'F0+,29!=5)2!++@0$E>8929AAB%8##39EG;?H)#+D*H089/,!?:>/+,&8-"@?F&A$3!>G>6E8>-FBH;9<10"BFA5*&H0F9584,H@=9G<8D'/$*;#&+)(4.HA<B'D.->$-F+AD1&)&-,<
@r347
NGGACCGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCATCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAANCAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTCAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATNCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGANACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCACGGCGCNGCCGGACGTGANCGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGA
+
!)!$&'+'"+*"&"+(+*)&"")%##*)#+%"!$(*'#+)#%)#$'+"#!!($#'&%"(#'$%("#'$*&""*$$+!)!*'$!+()$&'%("&")'&%*$"#)(*$+)%##")#+$&&%#*'!%+"''%!$')'*"!'')"''+$#!)"!(&$+!(""+!$!$")!(%')(!)+"))**#)'%$!*%+"!)!##((*)#(+)%(+)&!"!)+%*%''+*+%(!(#()'(('*)"&'+)$+(+)&)$*)$'"&(%%'#(&"(#("+(*%%+$"*"+)'''!+&!#!&(+$%#%$""%'!(*"($!&"")#"%##("())""#%$!$%*+#+&*($"'+*#$%')+%!#$$&()+)$+%!''#%(%&"%+!+!&(&#*())$+!#)$&#*$)#&+*+&&'!$&)*!##"$)+*$!%(!&##$!%'&#&%!(&&##"(($(#))*#&&*""))!($#"'$+$###($%%&!&!%&%+"(**+)')%""#%(*%%&+%$(+')'('&$'&"'+)(!&)""&*))##%+#&&(%(")%"'($"#+**)!$#)+""+'++'##+")&!$%'%(+")&'+)()"$&#$#!#)''&)#"+$()!%*)+&))+!&'$+()&"
@r348
NANGNGACNNTTNGCTNANGCCTNNCNNTNTAGTNATCNCNGNCNGNGAATCCAATANNNNAGCGNNANGTCNNCGCNNGTNNTNNANNGAGGTNGGNGNNGCANNTNNTNCNTNTANCNCTTTGTNCNAANTNNGTCAGANGNGNNNGNNTTNNGCNNNNTNCNGNTNNNNNNCNNTTGTAGNNATTAGTTNNNATNTNNTTTGNNGNNCNGNNTNGGNNTANGANNNNTNNNANNCNGCTTNTCGNCNNNTCNNGNANTTNANAANNTNNNAGCANANTNNNTTNNNNCNANGNAAAGNNTTNANTNNANNGTNTNCCCANANATANTNNTTTGNANCCANTTNANGGNAATAATCNGAAGCCTCNTNNNTNAAGCANATNGGGTNNNNNTGTNTNNNCGNNNNNCCNANANCCANNNGNANNTTNAANGNNNNNNGCAGNTCNTNGNNANGCGGNANANTAGCNN
+
!$"$!$#$""$$!$"$$#"#"$$!!$!$$$"$#"#$$$#$!"##"!!"#!##$$$$#"$"$$##"$"$#$!"!"!#!"!"!#"$!$#"""###$$#!#!!"!"!"$$$$#!"$!!$$!"$!#!$$!!"#"!###$!###!"##"!$""""!$#!#$$#""!""$!"$#!"$!!###!"#"!"$"##"!$$#"!!$#$!""!!!$$#"###"$"#!"!$$!$#!"#$!"$!""#"$!!!!#$#$"$#!""$"$#$"#$$$!$$!"!"#!"$!"""!###!"#$"!#$$"!!"!$!#!"#!$$"$$"$"$$$!!$$"#$$#!##!#!$"#"""$#$"$#$!!#$!""!$!!$!$$$!$!!#!"$"#$!$"$""!""!$$$"#"#$$!$$!"$$#$""""!"#!#!!$!!$""$"$##!$!!""""#$$#!#$!$#!$"!$$"$"$$$"$!#!!$"$!#""$"#$!!$#""
@r349
TCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTANGCTTCAACGAGCATGTCTGGAATGGTTTTTACTNAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGAT
+
1(70D27=-'#(D<0"'.><??A?@DG%/>(D$*)823#5*'&"C4G98G+:*2(;3A<-7F<<9/B),@H'C1#9$:7.D,=HDE+(B*!&!2G6;&+F67C'0GCC+E7=E6*3/1E)?0%;$4:!5E&!500',=
@r350
TCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATNCCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACNGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATNGATATGGTAAAGTAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCNCCAAATACTGTGATGAC
+
;0-EH-A#2/5B@2F<*>19<&&=/-EAA661H-&=@0;)8>.7=#60*C58.DEF$!1=!,3<9,,43<'->C(D@$!$03>444!?3(/'A1!<4,=D@-GE$6+G$3;@@?#?G6)@3D=&468-A"#!:C"C5GE#E0"3*39D/@6)(1A.<H:6?,C1=H7F5+B$*D7-!76H;*%G'>FG.'!#G.E<7'-:2&C:0'G/:%(,5;.9*/D$:3.,+(G=@$0*=9>H'211&5$,?(/,6%>*%7#A
@r351
CAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAAAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCNCGGACGCGAAGAACAGGC
+
+!-FE><B3F=9%,GH%#H$E2EB.3+9AB=2;#D,,A$B;>ADB0.,%'"C$16+/*70=7C*2*"3:E"2C>?',C(@CC230@*17@+<$CC/>305/D08;!:61':!$$
@r352
ATATNCNAAGATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTNTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCNATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAAC
+
"!%*!"#%+%+##!$"#$()$!&'($$')&'*!#*'!(!$#(&*"*#"')$&"%)$")%%+%#)"!!"'#'%"&"%(+'$!'&+$'%"%$&$%$("&+"%'!)+++$!&)!%)$$)+($)*%#*'"'!$&&!)+!++)#%&*(#%"$%+")#%##$#"&!+*+'+(**"$%)%+#)+)+!%*!&("&$!(!*'))
@r353
CTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCC
+
7%$97?:4.=1@+;H3)E$H4BH.7/%&4@.)8<3":05/2.GBFD)@2/GF54H>(=:%-"786BH@.FF;#)94:"42(-4(<-5E".G!@,C#26:E$&6#"$
@r354
TCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTT
+
F%?'C9G%>(@G/"":*47?+%1D!EF52GD,3(;F>9$)!!2/&:7%H?BA+G--F>:)G&5>*
@r355
GTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTNGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGNTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCA
+
+?+&%/,+D>3-FC2ECD>F68?2)?$",<B+%,,3(0#53'8-;=*B='H),FA*0*1;H1C200C4G9:7<08%&=C6;"&5@<<+>#.8$5B,E&7#B#;G##<$AH#,14EF$1C/2%@?7ADF22)1A-C31;$2)6&.+H%E6.DHF8:008:-=9BH.;&C&%%46.-EB4'86*8?0H*!D7.267:-:2<<.)A+!G2"+HG#05;5<(8
@r356
NTGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCANTTCCAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTANATT
+
!&A0-C%GH7A87=$#=%C8D#>3(3=%1#81:"0=@'E$E'C?FE@AE>+F=A5:G&6$&930.+A=+,H+1F+H7#8%<H&=DG4-25-F$5H:7:+%<;+0"8:=;E!&6.6CG=D>2($584?9>,F9E10#9$630H%)/8$=.8)FB!?891C)+&E)#/F-@-/9%=4BD'?#!
@r357
ATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGGGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGNTTACGTGGCATGCTGCCCACCGGNTTTCCGTAGACGGATGCCCCTNTTGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCANCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCNAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAAGGGGCGCTGAATAATGCTCTTTCCGCNCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTATAGTCCAGCTCCTGCTGGCGGATGAAGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTNCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGG
+
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
@r358
NNTGTCGTTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGNTAG
+
)%+*$!'")(!"!*()!"!#'&$!)&'()*'*(!%$!*#")#$"+'*+&(&%&&"
@r359
ANNTTGCAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAGGCGATTCATCCCTATATCGACAAGGACATTTTTTTNCGTGAGCAATGGGTATATGCAAANTNCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTANATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTNCTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGNTGAAAGATAGNAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATAT
+
##!&"$&+$*#)!!$#"!%*''!'*'!*#')#&(*)'''%#'"!'(+!(+%)+$!'")"%!#)!!"&$)+'+($#%"'%(&"''"$'$'$%#"#!!)$"*$*(#%(+$"!+)'('+'(!!'%"!++'*'#%$"%(#&&(&&*$#"#$+'$!#+'!+#!%++!(')(!$)*)'#+&)&*'#"""($%%($%$!')&'%!&#+(*"(#%%+))""%+")(&++"&&&''%)##*'(!$&""'&#()$)+)$)$%&#$'*(&&&"(+!""&%"!'+!+#*#&$!%**('##&'"'%$#"&""!$(!&+(*$&"+%$#(!"'%!&(*$""!"'$#"##+"&(%(!(%+%+")$&)(%(#!'+'+&'##('(%('))(&'*(%*$&"'&&!(#!")+'**#!($''*)#++*%!*($#%%$)"+)*+#&')*)(($*+'!%!*$&('!'+(%"(+*'$!++!")*!++&"($&)&#%'")!$"+!%++%##"+#!)*$%#*$)&&$%$&#*#()""(
@r360
NNCCGTTGCTGCTGTGCGAATTTATCGGCCTGCTGCGCCAGCGCGTTCAGGCNCTCCTGATACGTNACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCANCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTACTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGANCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTATTTCAGTGCCTTGTTCAGT
+
"!:03)3***<$8%D(5>,&).CC:%#=!=+!%!HG$?3<2H;/=<!-&(4!7E(*CG@4!BEFB2%09&#G?#=<,=';B'2>FG<,A1@59B1<81F188.1$13>7*$@8/,@,?.++H"=@6C":C0,.C7G:#%#5&:!95E;?,8.0H2=1:D=)G6,?H8/*1&25E!;E0@43(8=%FA.B3!*%$'2E45E7B%*D6A>>EHB18A/GG,)6BHB3G19EGF4H$0:E,6DH4'-"3"#;;;4>/(7@/"@>-"C@E=EBA,)?)56EA;6*)&D@!%@,&9?.(#2=/?,/&:)E;#AB/-:$;";@E3?461E4F70F4<)C:B04*:"'.#:)0GEH9C2H$*6##'D7=-"43.&0'';:.==9$?#&:C8?9@*)%G'*4=E@4%2A,D3/29*A?!/D(2$0D,>:F8,46)3#BF9$&?;+=@:7#47#1+1A3
@r361
GCGACGAACTGGTATCCCAGGTGGCCTGGACGAANAGTTCACCGTTANAGGCGTGCATGGCCACACCTTCCCGA
+
%B4GED3>:)5",;6EG(E%6A=9-5<$,!*A;>90A71/-FE45H#D#&*B-8)E8/GA'2C*EH?)H45%!6
@r362
GTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGT
+
E<#1#E0"HE#+<FH5+A(H8&09;;<'61,0&>>?)--3%45;BE.&!84*/#"%2H+4:F6<*G$FC5AC%,0$A/=DH4>/%/,C#7$9D6"&>:<CG:-4).@$F5?9((D0E%1G="E!*
@r363
GAAGGCAACGAGTTTTAATCTATCAGTGCAGAACGCGCCGCNGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGCCTGTCCANGCTCCNGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAA
+
+EDBC8@;'CAA9%$@/:5$/$1=6,#H+,!C50:C?&E"=(9D;';3A5.8).3H;1HCEC,!7<"!4#("?)H(&*C"#=C*0G5<@>5+!@BHC5H0)H$A&B*G@7&8>%,7#?FDA6*',B5DB4(#B,4,"76!,A$3%++@F%)92!$3?1>9@(?.3=?1?B+.;$%B53<,$91)EG/">3-(48<3;-(6A"?#8?@F;
@r364
CTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTAT
+
.6!2#096#!)C#1>>F+0%#C!#$$F0D:H,CBA.9'H&'@A6DA;:<;9$42"?E@,=7F0FF,?*=*0!$(A06D&?E.2//1(:,!)7#!1=5?:$*%D(-"G":"$@8$GDG-?-%%H)A@D4?H8#6@&5G#/@6C)<141<C"3)$D21G>?,@426*BD85@9,.**;30;#E4;C;
@r365
CGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTACGTGGGCATTCACAGCCATGTGAGAT
+
@=2!HH.,-8,7C;7.)3/6,)<3**&0+(A171,F%:A'$/>B;6=.$:/$",A998;#%A?($')FF!'8++>
@r366
CGCCCTGAAGGACCGCCATAATGCCGTTGAGGAGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTNTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCCTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCNGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGTCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTANGCCATCACCGCCGTGCAGCATGTGCNGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACT
+
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
@r367
NTACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCNGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCATCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGCCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTNACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGNCCGGCTCACCTTTTTCGTTCTGCTCAT
+
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
@r368
TACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACANCCGAAGAATGCGACACTGACGGCGCTGGCAG
+
-9&"B;4??57578>.>857+.E<34=/2FE7B?8G6F3!C&(/C*A9?'C10=<-984>EF!<83B%1H(#H-(+F46>2&6:+$HC2>%++(!1,E<-!*(A8;':FF&D/
@r369
AGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGCAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCATC
+
+"!9&%B4(.#=C5-H%*'.")((G"A<A*-9C*CC!"50H(?(7B!,F"FH#7$>BGE/*2*!77=E.EB4929GH;5F(E21-!<//;01.#FGD97C5!=:B-;.):;.E5/7"AAC.A%*//"7C$(.42D3G'6%(2
@r370
TTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAANATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATC
+
G222F:&0'@2;&D,F6D3FB<;=B74=H.'4?)E,8'<A!C'$G:5FB;F!1"'?9&H84<2-3?('8+E307?;04/*8H%:G-A(1!5(.5=40>?':;F2*+.<G&48AC>"C:A2(;H(H<%F+/=@A*B@%,;%F**DA;6'@/E*3+FC-B6,%#3.@%6,A2&=05BGD(@0G5;*!@16;$$&=0(A$$A(673.&C?%4'B.G555=1;34B?+?G3G93(-&-=&.6,7>C%A=!<@+5=<2$B!<0GC0%+&BE3;%"05.+*<.?DHEE%/'<27!*#;,'B%@4'HA2:&B0=FD;%$.9*!8#H./$9B1>.!2&8@&)<%-B3C*EB4(!?+>#9-*>:5!/':;54.*44(/C(*8&5<&5D4,H73$+&3+2005-13*D(+8666(H;/228#1#9"6)E"=.(+A+
@r371
CTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCAT
+
:G8.+=F#B$6B#E+HB;13B3H:0-'F!2740H/4!#?B*.HB4G:>=&
@r372
CGGAATGCTCTGANGAATAATCTTTTCTTTTTTCTTTTGTAATTGTGTCTTTTGTGTCCCCCTGTNTTGAGGGATAGCAATCCCCCNATTTGAGGGATGTNTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGNTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGNCAGGTAACTTTGTAATCTCGCTAAGTTGAGTATCNGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCNTCATCGAGATCTGCCACATTACGCTCCTGTACGGCAAAGTTACCTCTGCCGAAG
+
)#"(+'%$!%*%+#$+)%&)*('!*$#!)+'"""+$&!++'(%&*('&!*$$((("!+&*)!!"*$"%##)+%(#'(#&*!$&&#&((&$$'*$#!$)()+%*''#!*(!!)""$$)(*$*++&*&("!+#((!&($##%!*!$*%(#$)'($+&$$(*%$%()&$&&#)&$+(&"*'!%'#$*$&)$$"$!&#%("+"'#!%(#'+)!"+$!#%)#$$()**##""&#"*+%!%&+#(%+()'(*$(()!%$'""%$!)&!(*%**!**%+)(%(!*(&+)')'"+(')(!%*%($)+!+&''"#&(")&!$")'&&+!%*$*")&*'+"+(')"()$)')%$*)$(!)'''#'%$'!%&%(+'&)%'(+*"%"%$+))+$'+$!"(+&(+(+#''*'!&+*%$""!#)&#+!(#))&((#&(!!%"&)$#)+(!*(%(&+'%&(+)&+""(&%&)!+))#%*
@r373
CCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCNTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATAAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGGGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACNTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCNTTCCACAAATCCCGGCGCTGCTGGCTGATTTTTTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTANTCCGCCTACAGGATTTTCCCGTCTTTCANTGCCTTGTTNAGTTCTTCNTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTAAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGTTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACCAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGCTTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGACGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAG
+
6?G&!=2#-7$H*C$!A=+832C!*;5,,@8%HBHA/H73D;;=-H&5?.*?G@.G6,+.$A-757D1?4<00=C8(/*6>*$GE()'3;*09.4039,8"59H<--'*9E=723F0E.G&$0H5:G#=A/H?BE$:9&<AH':4?<::D(!>4$+BB:<G;/$87$F&B6C4)'B3-BG31EA%3;5G(9A:G;<2+#1H)G";4.$!3@<:=1E5#;H4$;D1"51BA.:#<&?A:'0)7H&?+;@&<.:;)!5&43E?6-G?F:H(/*:&0)5EA$1>/G7;.7:8(($?"(,;+7>'7.090&;:--,&'.&C&!+:?&C:--%'9/GA!5<+,A8%,E5>-FC.<B+#@<-.=A8??'.0@&FD?D4/.3#A(3"A+$>DF#F2!B*!1"$!*.@+8C/7!8&(G#E@2?)3"56A+GG*2=8$?G$(5!0=D4C,,=GF8.=A*7.D!2:E(1)"C)@AB28*C-E<;10;D>4!D3-&'-B=C"F?0:!2>92A?F3':;A*539;79$%#7(3H2$2=DH;(+>.)='&B:0A/'0-@,'=5&%1@$A$'C)5:73"8?6;C4=!#-1.#))"CAD?DEB*;554,??@8E&>@75;12;.27&/C)&.B*G;.%)/,%"09,,*DA!?'1F&.?$EH4C/G-:#-%*?,*%+?A8%>A"B,);9$>&6'$9=D92@:90?!A5HAHE)/'@1/C!78D%*%/4%;D;;1*7!)5D+?@/5);3E=A"C?5B>%,!<.F::E?"#;80B)A5?E32<8314%)=?,?F:+$.>G!>(36085598>--4F%,=H.<-7($(B5::,:=+2,HD6;+'#@9D0%65&<3C=>A=?&?A,'.1?9DE2!D&5-&2B3#==,*/2>>$&3<#4AD1@&)-F#>-#5,;(3=;@%4'5?"(?E1899DH$26>5"<.<'>97G(7,)9F<AH=/')B-2>"8@?G)&60)6*1F<5*.;(.G/%HG!#05%H3$C76/=)D8,=4'H1:"E19621/.$>C37(%:.0*HF*E-B97$?3D=G%(F-4/5)$E%%.)71F%B-0C0),09E!B=D=##881,;+&:<3"+D7$3?1D/.C-5?E(--'#1?06FHA("&/"27E/;0#0GH'8%&H25%/&F"H/?:D9B8/"0"0,%H#/:ED5!2,#E%H/3C6.#1+GHHE(;@%#0%6BFC!%5-)5)#6!45!)>47BB12<;@8FEH+%=<1FG*-?"5=136720-&H.<&5;*?$:D/&$+?.$DH.1$3=C&,+&'*,&EB?CBG*51H9)88;".C"/4B7.5,5;6GG&(AG@1&A8)*0EA7'4CG)-!;>>$+G0&(9D&@+;AG:H8+/+'H>3H>
@r374
ATTTATTCGCATCNTACNATCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTNATTATCATCGCTTTTAAAACGGTTCNACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGANTTTGTCACTTCAAGTAAAAACACCTCACGAGNTAAAACACCTAAGTTCTNACCGAATGTCTCAATATCCGGACGGATAA
+
'()(&(($'($$$"'**!#+*&'&+%)$!)*"('#+%*('#$%(*&&&&+*"$(%*(!)'+#!#)#*)'()(")+'(#!)%"%+$$$+()"#%(&)++%*!($%)+'+*'*"$*)%")"'#&*%!"($'"$)&)*!&"&*&&$&%'%&((+"+'#"'$$("(*$*#"&'"+*!'((""+"')!+($+!&)*%'(#+$'+#'(#%)%#*%$%"$$$*"""**+))&%%!%**#"#)*&$)($*%('!$$(&!##'+%+&%$(*)%!)%#!&$('''"$!#+$'$$#'$*#'("(')%#)*!%&')
@r375
NATNNNCAAGANAGCAGTGATGTCAAACGACGCAGCNGACTTCTTTTCTTTCACGACNTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTATGAAGTCCGTGGCTATCTATCGGCNTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTNTATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGNAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATNAATTGCGGTGATTTTAATAAAATAAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCNTGCAGTAGAAAAAAATAAGGCATTCCTA
+
"#!"##!'(*'!'+')*$)&)&(')!%%%&$"$%(('"+&*""+$(+"+*+%%&!#+))'(%$%!"&)+$&$)#!#%*)")#))&'#%!#*)$+#!+'($&(+*%+'$&!#')!#)'&&%)#!*)'*(&"'#(&##%('#%+%&'(#+($!$)++&!(#$#)'+((#*$'!+*)+!!((&+#'+)$"#%()**#&"%')&+(&&"#$)#*##)+$(#++)'%$$%*)+("&$*!(*+*''""+*+!)((**(%$#'*&(%%*%(#$)%%#'$$!'"%*%+$"+#$+*(+(+#'(!#$'()&!'!(*+*"("&''%!%)&$%%#'*!%")$+*&!!)))!*&++"*'!!!))#'($+)(#"&#(#($'"('(*#&"#)%"(+!*$'#"()+#$(%)+"*$(+!*(%%$"+*&*%"'$*%'%%+(%%"()&!$#%)'!(%)"$!"*$+'%&$)$&)("(#!&+#*+(#'"#)&(+'&"(($&+&#)%%*!(*$())))#!*(+$*!*"+!('&"!##(#""''!"''+)+('!)$(''&!&'')'
@r376
GANGANGGGTATCCNNAGTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGNGCGGCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCACCATTGTNAAGGCGATGTATGCCNCTACCATTGAGAGTGAGCTGGATNCG
+
'%($"&')%)&&$(%&"+((#!&%###$(!!$!"%#&+$*"#'*!(&$(+"#&)"($&#)))')*("#!$**'#&"+#)+')""%!'&!!(!(!%'*!&##!&"!*++!(+*$)&!&"&*+&(!"&)**&*!!""+*'(&($'$%&+**))!)$'""''($*+*(&%$$'#(#+!%+'"%$%*&''%&#)#)&%*(&*"*$$")&&%"&!('#%!*(&((&+&*'''$&%!!&%'")%(+''#
@r377
GANGAAAACTTTTCAAATATGGAACTCATCAGCCTCNTTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCNAGTGGACGATGATAAATTCACTAAATTGTTTNATGNCAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATNCAATTGTTTTATTTACTATCACAAGATT
+
2*-CD@9)5;B?6H6//-B>D)3CC)020A?!&*3<0FF6*>54/E,G&>*(3-:0;-><1%1!?@@@/#8/*E02BD)/G<H02B,BBB95@""&H=CEF;,("AACA;C4.<'D,G#(-?H5?B0/&%DD0*+;?-)>FE'1#!D3=C3"/*=;,?'8-?=7<#.7)*G0-H&AD"#@+<3!F
@r378
CAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGNCCTCTAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTATGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTNTACCAGCCGGGGGCAGGCACACCGCGCCGGG
+
8&/);(':8+<005'%'D?HBG!46H.3$57+F=DFH:8C0:12A3E$:,G;D0,HC%?:!76$,4)2C6,$G,>9%?#F2D99+E9EE02.7H''-#$5D58=2(9-+E&2>""A05;F(H552;75B&E6-F$H97!:A<B:AC(+87-'</)DH:"+&"C@:/G0>+!?%8A0,">$"+6)D!7)64H/3:/>!2:D8(1"H2G>#,&#<?H6'%EDHG8#(=60H!5*7$)9*?95E<7)BA?@4"<+F7F)0!FCB@DBF*BEB185G:7B8!!.6CEE)=B+H=+;0!%=&3!96="(@?EF";3F#8HG?B!F%1019D"(
@r379
CGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGCAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGNACCGTAATTACTGTGAGCCAT
+
@,4H@185,/-6@!#6CH!C'D=H:B+CH9:4#.:*'(FC$>4.+(%:-,H#,>FCB<;9!7&B><A);F3)ED6&2=F8-.3!4-@H;8*6%'#%$&B298&H;3A&AG&&
@r380
AACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCG
+
-BG$.$6>0D.A1>H$DA?)"F%07"6+&8-;3>A&(77"86F7<G&=E&,55E)4;?B(?5".83(G!*F:3C0?.=(A/0(C#G!0=&#'H$?.>7+A6$86/.6-
@r381
AGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGNTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTG
+
C<"(5;C'%2G72FE?:/:9=G>H6.7<<-BB85?2,(F3@95$13(B)*;0'1:H@$045.5B"G,"(+(E$69;4!21&107%2<=DG>)<D)$.A7<25;3-7DF>8A!H?C1'G$%7#)::C5E/B#7"G(>'9;H='
@r382
TCCNGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTCCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGN
+
#'(!*)+*()$"""'*'")!!!"&!%#!%+)!!##(*#%)%'(++%)!!%+!&(##+"%!!#+("+$*&+)$$&!"!!!##*$)$*+#!%""+%$+**++*&!'!')(!&!)&%%!'!++#')$))+"('##'#&(!"')&$$"(&(#!)#()#+!*%(*&"#+"(*+"&!%)!!"$$("($#)+""(#$*!$*($""
@r383
GTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGNTTCTGACGAAACGCCGAGAGCTGTGTGGCNAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCNCGCNATGNCCGNTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCTTTTGTCGGTGTACCTCTCTCGTTTGCTCAGTNGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGAAGTAAATTGCGGCGTGATTCGGCACTGATGAACCCAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGCGATTCTGNCCGTTACGCCACCAGTCATCCTCACGATGAANGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCNCGGCAGACCAGCCACCANGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCGCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACNGGAGATATTCACGCAGGGGAAATATNTTTCCCCCTCCGGCGTGCTTACNACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTNATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCT
+
+$$()*%""#*'(#'&#''(#!*%+()$)!&+#!(%()%'!*+!#!#*&'"$!&&+!+##""*+!")'"*''**'$+(&&&&(((*!#(+&+#)%+*'*+*&&(#)*)%+*%"(('))&&"($&#)%'$$!%$()*'"%"'('++$&$'$%'*"%+*%$!)##+('"!!!%'#"+&&##'(&&")%!$('++"$)++*!!'++%!%+)&+%+*%'#!'+$"!)%+"*$("!'$*%!*!$&#*#*(+#)&#+)&&&&"%((*+*&+*#)!'#&#*'(&'(*&$$'"!'"+)#()&!(*"*'%'!**$*)$(&#%)(*'%&!#*+(*$+%##($#(&$)%!*$'$+$%'(#)&'*&%%#!)+$#'#!(#((%+"(*!)*%*#"*'+*$"$)+'!%$(+'!#&%&""&!*'"###'""*('"#'$&#()!''"#!$&*""+*&*'*)&()#")*$(&++&$%"&'+*($++++!)#&+$$##&"!*')(%$"($+!!%$%&(#*)()(%*&(")%$')'')*)%&'"'&*#!$*)%**)&##"(!!%&+%(&'"&*"+(!+)#"#"#**##%"&%+''++$#%(&&%$)(%+'(*()%%+(&*)(!$$)&#$$(&&*'&%&(*)*+#''%$+&"#!!$&##(%("!#+%*!$'**%!)&"#&!"(+$(%++&%&%%$$"'%$%*!%"+))$%&)$%!'&!*('$!%*+%+*"&"%*"*%$')'%%%%*'"%$)!&&'*)$)+('#(*+#*!)#%"&&%)*"!'%)+)&"!!#+!&"'"++"+%$+!&""!'&)#$)!"#"%!&)(*))%(()!)##((*"'+%')*'("#%#!!%!"##+"()%*""*"('!)#"*%$!*#'+$*(!'!')+)'%*+*!**'(*!)*%"!(!*#%((+$*%'+)#$!#*%(!$'&'*#()"*#&'(%'')"$"&%#"%(+#%*)$*+)&)&(("&%!+)'#')"#%")()($)++*"#*$)))"!')"&++"$($#+(+*(+"'+)'$!'(&(&'#'%!!#'+"&"#)+($#!%%!*(*&()&'+"&$')%+'&%!*+'$&'&%)("!&&()!*)()$!!+$)$"(%($%((+
@r384
ATTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATNAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAG
+
"<CBE(6E%C53>=DD(@4?#9!A,@0"$)*.!/%B09-30&<4$+,7G)*BEBC0GHGC0/G,D*E$$?,E+%$=&3EF>5G)62;?"$D40"6.@.3*.;00(F?:(1#E;#0H.+(2DA#F#@9@/>6CD>#1E?7-;<,&B(*?%>@(G?9=2"@>*A/AE?G-B+8!G'='<'58H1AFDAEG'GH1"%@><FHHA#5B81H?-5$D:=7=-E@D)'C)6)$E!1:E9H+&A;=G("/103H8DF/#?)3*:$$H3)53A36E<H
@r385
AAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGCNAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCGTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAA
+
($E'F399ED%,/AD*&<:9G.BH+"G#C!01;%<-869><0G$;0E@C!E09D9.,%5+F(/H48.47+=C,=C=+;&#)*C3?5/?69<;*9,3CD-9#F<158!"0>@A$/75:924>%.=8CG-E@D@H;)?''/?7+,)$<%E++4"5D!'-/<#=2)%4D$B&+'?6H!,E-%<%11$0?>;0"B6EB#7,<E1F*?%*7(FC;!%8=;00$44"-$H>&2A!F56"H$19%#:CDAH@C"EBF)8%(E%48?8!*<>;3*F->/5.,0/%09';$5='8;@50).(6A0)2:B2C@$=A'
@r386
TNTGCAATATATTTTTTCAGGTCAGACANGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTGTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCG
+
*!3,#+0):$DD96@!:)F341F?8A+/$#=C?=%D>$F69;"A4@'HE/=(::7?DG$78'F><$=/F'8-#B*?+,1>8)$5+39(1&AB"#!-&+G<"C")2G;0+@7>E'C8.0-2D-+4/1";:1G<5D3*:,?;B0'.8>?B$7&84<78'69&E2#0./@B7!:7*C+6''.:A6+@,)96:(44G!0?F83+"D8>42$1B/#>+<7"D*"09<')F-$&;!H.@7G7<'0@1$C1.%#>6C@(%'8+%EH$E6&6/:+)'3?964"0;)@
@r387
NCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGT
+
"28<19,C8.7,*;)G)H<%*9C(C@*-F%7,84'0*28>/#"#*<4<2":0%E9?-)%580=#%*?)
@r388
ACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCNAGCCTCGCATATCAGGAAGCACACNCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTNCCCCTGCATCAG
+
4AC7F+A"AA*03/A/6,G/G&349*!##!5"%9F'#6A7)A!&?4?4A<A@+EC&%<EB>$<(F7/"'<8%8D,0-;3B">C'&=@49<=/+/GAH*-3C.-9B:.$EB,5F7/$F/(;34F@H
@r389
NAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACNGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACG
+
"G,@E/#/#"B<.'4.D:638*5/F9+6/D@7$DC/."=;4?A*(DD$HDH+9),C$%?F/7(,,"/.)FEB0+99,;8-&<7!'/,&D&HDG9#&31<",5*"@$C#%'0.=,6.102<*A.&))H,&.'!<6?$'4AG8H+@18B4".;2@?%''%/FF0:(0/G1(5@"'%54F-B'F"*C!'&<2+;1?+BB"#"F/5$4*'/;@$;@68*-7#.GH&=+$7F:BG(4&&*-E5>,09;."7FH,A3>2.$3-''+7$3"A>31@G9!6B@D5,$%*GA#FD68'=>'5H;0%+7C%/<"&2DA@B3B8#H>1FC*">#H@08A+9#E&D2<#"E.-#''6BA4,'5'4<@F40/%C68,8-2D7G+%;2$=C6."@39D=A5!%2063<C*88.0>5:"%D(:
@r390
CAGAGGGATCTAGAATATGATGAANGATAGAAAATTACGACGCTTATCGGAAGTGAACNAATACTTTTTATATGAGCAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTANCCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACANAGCAGTCCTAGGGACAGTGGCGTACAGTTANAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTNCACCA
+
#6!.!0113DD$9A7);$"*"E*9$98@!$%(A.)GGG%#)(:+@$$C35>.EG#(?$?F94E36;:G.AH(H5/@B8,,C9'"94C(>%&)1+?8?9'.$5G7?%">7#F%C65;(1+0093;6)D,@F%&<$9/D0C2B>43"=F2D>/(,*"D=929!>3H)H3G-/3.=B#AH4,3F64$#@E.<F02979.;>7H(!F1@$!")8&"@;:HE0H-CH>,CC2/-8;'.=+48#%8$HD=1FA&,9<5/CH@?G@>#3C2+A0012*>+AH/&<=H"+;)D+H'031BG%>@@#7"!GB(%91&9E9AE#"D0>*76
@r391
GCCGTCTGCAGGTTCAGTGAGTCACCCGGCATNAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCACTGNGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATNGTGGCGGCATACATCGCCNTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATNACGCTGTAAAACAC
+
);6,:#'"46F0$1!H#A6C))5A#+5>:97?&F%7!E1*D1-<%-;:(?C%4*;D4!$/%:,##2+C=)F:EAB3/"1.,<E@((%)GH.=2+-5#-8F*B0B-1)2$..5%%1/)-3$:2=HH@D/=2%<@$5)6G995#B*D$&9$27'-=D%,""4BD50.8"17C.':E;H>D3;1=D0H1%4A:-:5FH:'E(G6'A&!)-;52/%D&AE!8;%*&1B!#@DE)3),ADGB?**E#!E)/6B7G3,#><C$14>D3)6/47?D.31(B3/13F""77C
@r392
ATTTGGGCAACAGGGCTGCATCCACACTTTCACTGGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATTCATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTNAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGNCGCACGGGNAGCGGCNAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGGGAGTGT
+
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
@r393
CANACGCGGCNNATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTA
+
$%!$'*'$!&&$'+"&*#()*)"!''#"(++#!+&$"(+%#$)(&$!""$&$!(*"+$"+$"'(&"#)'$*)()""&*%#$&*(*%#(+(!$#'!%"##*$"%(#$%&*%**!(%"##!%#!'(++%**)(%%!'%*$"+#$'!'%$****&$)%'*()"')((&)$(++)"$$)*(!'!+#+(
@r394
NAGTTAGCTTTGGTGGTGTGTGGCAGTTGTANTCCTGAACGAAAACCCCCCGCGATTGGCACATTGG
+
%1&H<A&!!H0#7ABG!,#H,*%02?!#8G0>FDC-%+32H:,A03,HCC+./.5"*=90H9%.EG4
@r395
GTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCC
+
$+'+(&$&(&&$!$")("$*'*&&"#"$%*"+%(*%'$'("!#)!'(&$&"!((
@r396
TATGTTGTGTTNNACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTA
+
+'>,'C5"7"'$D1*GG3&;(#!E>689.?<8*##(+"".@:%5(!:#)H%A/7A+"'0D5778B/#A-
@r397
NNTTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGNTTTATTGATGGCCTCATCCNCACGCAGCAGCGTCTGTGCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTACCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTNCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCC
+
'!+%!*&(#*#%"#"#)#*#!*(*+!+%%#++$#+*++&*(+$'%"!%!**((&%$*+)#+(&$''#(""!)#"'(%&'$'"""#"*$(%"!"$('*&+**$$+!)+*&+""(("((+#()(!&$)"*##')'(*+++#'")&&#$*+'$'#'(%&&$+#&&**!#(!"!)$((')))"!!&%&*'"$+"))($))(&'%)'#$%+)%**+$'$&(!%!%('&+%*(+%!+#*+'%%!*#%&&!$#*+"#&+'+%#)"&$(')(&*($)*&!+'%!!'+#'+*%+&+%'#'"*#*+&+&'+'(+#%)*"%+)&$+'"#%!&*$(
@r398
GAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTGAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGNTTTCTTTTGNGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCAGACTGCCCAGGAGGCACTCGCGACGCTGGCNTTAACCGGTGATGATGNCGGACCACGNCATGCCCGCAGTTATCAGGTCATGAACGGCNTCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGNCGCTGCAGCCGTACTCGGGGATGACCGGTTACAANGNCATTATCGCCCGTCTGCAA
+
0<GE)%))#?3?9)<HH<%3/E+9&AD;,(H5='A$/B00C?-4C2=<<D*5F(="520EC2*"'8/<G$0-:GF:H>?=!?A1'F9238@0=-C/-3D'&;*6E1+&8D>AE!!?0+3)/9F49:0G@("&4$E+$#G9/'(<<2%"B3*=D,B"='+)2-?=*'/A346??3C77C?+5A8=0$7D=FH*3CD"@:/>H0""(+-?+'*8.9<@*%'*#20%<7-<E/#!3?4$!>)$&<56>'*GC,=$%,?H5&!+/<)B56/C%951+@**,H-/E&)2B@5@)>*H+'!:H'08#%0#@A8+C!'!G:68"&.A?$E,:<=5"35"#B"08("3EHH>*@4'F,E!%$&9DE
@r399
GTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCCGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCNCACAGCGTAAGGCGTGGGATGTGCTCANCGATTTCTGCTCGTCGATGCGCTGTATGCCGGTATGGAA
+
*-&,>9,=-A;CA<C/;:G9#%*F8ABG83:0%G>?$95;)B',C$%@A@@0=3!BB;=#2"+6'EH#39/;7CGF774@<#%&29E&6+-07"82#CF,H:3,7*.-D)7;A7.A:!/$4.0@=D0C#5D./(2GH-FC@B(=06G9#+E;F+3%.FF!?(200@/&'0B#A-)#%#@:4@4/:#;'*8
@r400
GCTTNTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATANATGCATCNTTGTTTTCCAANTATATAATTTGACCAGAGAACAAGAATA
+
EA4#6B#'H:>#0-FH0E>>802$!409&A3,@2H417&E#?=ED&*H*!=4/>)-41;F=)E?D"2:52@-0>46655&1F?E2G1A>D>19,-*)<*%*G-#A#;<31(8/)3?6!$:6A"
@r401
CGCTTTACCTTCGTTGTACAGGCACTGGTGGAAACCACCTCNAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGG
+
(0+=.*3+1@$'=9+*6E'5/#;=$HA0!9#.*+?7:4!A7+=@*9F73&GBH8788G(G,)<F139;6$//.C*%=B0
@r402
TATATCGCTGCCGGNCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTANCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGG
+
.52=%E&)>G?"A=A3!%2(HGH$5*1&E-1B9C/5)9!(<G#7<#<D/A091&GA&&4'D=H'!%G#'>;F8"8B.8B,.,0A3E0;!,.4)6@.(+H84B"B7<8AGFDHB>2"(@3+G>A5-F9$D'@;$=9BD"13B2?E!67'#*"1>)(:.F)(D5<6*"+;=14AF,<)'A/B!B?F*.6;'(,(CE;($F6B(G(7%BD:A.'B"'H%));'#HE?.H1H-@B+28!7G2(A7;D"3?G7
@r403
CGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCNGCAG
+
1G:H,3>=5(+D.A/#-@D?'CH3@3-<%:>6F8C)4+("0G+5<?:5,%;:A+!1)2@H=%#6&.0,09<H'A)+5
@r404
NAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGA
+
&%/)4H-B#F;G8>=?E.82+,<A(##F#E0372<F%330
@r405
GAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGGTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGAGAAAAGTCGATGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATNCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCG
+
420'/#E"%C=)5FD)9B(>)CB/16;(-$D8@"2/.F=D(B20+5.8$2!<G"6($'8"2:#&1H5&02,G!2C/55CH(8B@HB4)D5F<1-(;DF?4$:F$'/7&9:3'G%?;-7&+5.AA,>:'3;/<G>7$".3#1>,7DCB9.:F,73HGEE:6"9(</@#G=)#@@!<E6:E%996CC574+4"@+32=@,D.<:%7.*4*A%6>,+>2"<).%C=<,36@*?%(BG#;D#F2HE*7%A@E<D9-AF=3F22"&!4C*@F1D%ED-9C(B12G5F-%'9!=,A97+4*.3@!0<3<F5G7F(7-=%"A;6*!*>+2&$/4B2&"(C9E1B".B3>%HE-2/"6;581E:+6
@r406
CGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTA
+
.B3G-/5B>D9+'/73256!<C=:%0<&+E3B7$6)@FGEC-=.A$A%*F>@,24+.884:'8-!,H>$4!%:C9(3&(&%41AD:#C6.BB!F;H,&$!:%>..0&*H!29,5:?9;>>F3>%FFB7*GC9:C9G"=@-=&,.CG"$D2=DG&,H:)>$!=1<?<"#&.5,;+@2)(A:&"&C@%=?90<2(>H<"5;))-?//CCE,C3
@r407
TTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCNGGGTATT
+
A(%<-0A45A./E3.#'"8F2!3.2-C'/7;;$@'3-150%6<(/7(G08:(.15$0=A>%&55!*/<@BC5C:2?2'A?;/F&&G9;/'2D5@=0/3,#G&9*0?A4H;D$>=7&:HB8+!?/':D:0+?@GABF6*&7%6<262+45!)!#,0A(E59G
@r408
TTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTNAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGGGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCANCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGC
+
G@F(DB3G1#'<;-;"*6:&,5?A<C*1;C#.</F@D;#=F0+&BC"'89=*C?G.>/3(@)4H-(5)05:(>%#3)F?24)F%H=E<?+).E.1.*>88<C/%%2<F=3D-6?",6:,#>27$++(&G:)(9H!<6!A/';D,#9+&F:*<F&)9G:+':('?$E:&2:H#(#3#<5*6=&7@E6:F#7A%)A-3E73GF$(AH,B08#=0.'!,EC#C>74B6D:)3-475.8G>,:0!/D8.)8*',0;/@C?$D62@!"0=156@C*AE6"EG5,%:*G4=63F;D%*6$,:22;63D742-15!'9@>?8=BCE-@#9#(062<&0"EB:B7>3"*98+2(*%4241FDDB.C14>D1=,C/;DC66BG<%)9?;??<17*"2$$%,5F7&"/"C*2<#:=!D8!=18058D$D;4C/?@.<,;F(45;#A.%4C4&GG27
@r409
NATTGATACTCATTTATAAACTCTTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGNAGA
+
"'+&*($#&$$++*)%!'*&!"&''%'"!+(!$!"%%#$''+&(&#")'**!&$*&+!$#%#%$#")&)()%'$+"#%(!'$!*&++#%$+*'!&#+#+)+#)+"#*#*)($**#"&!#(!'*$**)&'(%%"#+$&#$!!+&((!$("*%(%%
@r410
GTGTTNATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTNAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATAT
+
C4'%,:,8@!=)D5H'H/;;!FG+:,=5-)@87(<?8*D/8$?@$2>:%9'9*?9F'&@0/2B/9D9,<3).(G<:<5"1)D4.@8?>+4*';$4BE5+F#?AC<G5?2!5A?1+!,",A9&3"'65EGH!GC>0>A"855((+-))9'"#2G?59>-:&0#*E<+4.311:3?/3D#.=%C"/A4>>?*'HB9DE'*:HA%?>@/4#*'3-3C$?)-A;++>+$HG2B72?;6-*3+6;(44>(>B98$AF1%FE5(@*GCC;(G=9CB.<FAF6!=%!D88G9E#<:$#63(6!,)!&>62'5(51&+<=:!(-@/97*';:FA-.G'2G74H4#+4-B5/863625""C/7/?@;=54.E=A3E.0H8.!4,/:H*5*)/H
@r411
CCGGGAAATACCCAGCCTCGCTTTGTAACGGNGTACACGAAAGTGATTCCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGNCAAAACTCGCCATGTACTTT
+
$*A4!E9(3<A340&B.?5A?9.,;)4H6-)D.AA3H(9A/6*H2#3>#(>FE13?3>95H1>/!8C!)6.)AE=@1%E="F:E/"#E?!4;9G&#F%:;)8!5*4@F2A(%/!.(B<B;=$"?F;12#3%E1%7(5"06H9?2H0GGB-<EB@0%)8/>!56"*#7+;CA=@3)A6/=B8,
@r412
GTCCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAG
+
+))&+#%+$$!()#""&#!#*"!$###(()&"&&&)$&'*#"#($+)+(#&&*%"$%%"()%!)+(!!($*"&$""+%&))&!'&*)+!+&$$!*#)%&&("&)$(!*(%*%(&&'+%)"(#!!*&
@r413
TTAATCCCTGANCTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGNTTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTNAACATGCCGGTTGCCAGGCTTAAATGAGTCGNTGTGAATCCCANCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCAGGCTTTTTTTGATTNCAGAATNAGCCTGACGGGNAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAANGCATTNCGTGGTTGTCATACNTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCNTCATNTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGNACAAACCTGATTCCAATNTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCNACAGAAGATGCTTTGTGAATACAGCNCCTCGTT
+
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
@r414
TNCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATNAATTATCAGGAGTAATTANGCGGAACAGAATCATGCC
+
$#)B(2F/.@)9,2&C(&FE3)*8+E2E@,?.#&%%D45;)<+C-9:6DB'#37+40H-D1%G-((2$G,"*!%=B'1-4<''F%C';<1<'C-&4.H=<?(D63F./GD+4EH%A-8->/#C#>/:(85!<#:<<3*&>1(2C1B)#D,-@$'19;$&(+CA(F/"
@r415
ACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTNCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAG
+
<@=9@"C%9-F;/>>6();/00B0FFB<4%"-#?,0E13.H@'!;FGFA?>09;:;>+ED/<61E0%,#*,;8:H,?/7'+$G104=2*32/,&"EB7E(;@73=G>!B(E&,A*&%0:";G:%@%6;#BGG&!*4/=F=6)EF<?>#7:H=4+C$$D"9/;C109GC1=G818G1<.F'E"5CAH$<41*A
@r416
NTTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGGTACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGG
+
/.4=H=-D:A11G?BB9B)4=;@F");9:0:#-;(/14%.25*=9B,<35*$DH0B+G?2+%)928?56D%)BD'!78?,7"F5+F1F!BF,D%89!E/:C(>AC':3!AA8%C46D4@H,=>#H*?",E<DFB@%>:'89241B$A2+$'.-<HF#90.B9:5(,2*17+?/4=@F(-F,1A77D"-D"5.D'C2D;>52&@H2@A9&H9<A'21-7F4.;82>,6@?G+%BA-5'9G5+"(?A=,%,F68!*?5HFH15(33+A?G8#7BA)99"B+F!.,E=&0F(H<7%@EE'E!00/@"!$;*6&()0G2;(=96H'D5H*40,3$84CC!!(3?'=$:<#6,',;7?G<("G++HA
@r417
GATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTGAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGNTCCCATACCGTATAACCATTTGGCTGTNCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGT
+
G-2"CAC)$09%#>$3>3>=6!'AE)/&'5=G==0>1(%6>2E*<24C1&.59>&!1$2&-<B5)B$D46=27=);=0"$11',(-?#*85+2G)49<*;5DH-:)EA35'.GG#+=!%(+AB$35#9>'-8@C:G&,DF>5H$#822!19)G7G4':8DE)0)3#2<G";E1)27?;$3;=H;B$F$:1"<,66)G8';?0-=$-(=+-*'F>B;0?-8>6-=/0#0*.'.:;/?,E&*6D(C*9"B.7=+=;?)+$.@B66$$C+5E/;"A?.;$)BE&)D$#"7C(A/@5F9DG$
@r418
ACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCC
+
H4><3/FE0(+.,206?/B-7B2?.-6..8#*=<;E=-?%)40D@;(76>4"','BHE<,9*?(.&H+?".-;C:*#"9.-
@r419
AACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCA
+
9B-(7,0-F'"3)7C1,D%>?.#"FC5GG6#@CC98$.04.07*4B:*53;!"3>3;0'G
@r420
AAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCNTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGAC
+
3DH9,36+##!?82A4'H4-&40E3,41#1/3<**0('8D>($E)@31&A)&".(+H:>=6=>350A4-#<%@4+$A+($8D8C="7=+A:9D(@18A/B@B2%F;&0(,G#*+-2'806<99!55D,08;()6HA-@E63$3+=@1G&*=;38BB.E/$4G<@,G61D5B!:*,<>("?E
@r421
TNAACCGNAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGNTGCTGAATCAATGATGTCTGCCATCTTTNATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTNATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAATACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGGAGGGCGTTTTCNTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACNGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGT
+
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
@r422
TTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGNCGCTGANAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGAGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCN
+
070B85(8G5-%!+H@&"/*H#<A!4F&??&@!/:88*,,?E-GE67F6'%-,3;:F7F=C-GE.8#;;)#BE?9;<)'46/:/#$:/7D6<20)A?"(AD?4%3$*242#BB8C-%80?=3F-+A140###9>1+&F<+4(;A)?3=@-$+-AF89->6&,9!G':.5G%4-F=-<,##DD+#%3A;B"1C?E=,%,%"7<A>"*DF%->)H:?6"0%%*D*22.4,F(:G7,9'D<;+,@B:E@B+!%+
@r423
GATTTNGANCTTACCCCANCCAACAGGGGATTTGCTGNTTTCCATTGNGCCTGTTTGTCTGCGCGACGTTCGCGTCGGCGTGTTTGTGCATCCATCTGGATTCGCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGNTTGGCACATTGGCAGCTAATCCGNAATNGCACTTACGGCCAATGCTTCG
+
)%(#%"&'+*&%)!!'#%%''$))'&!#%%"&'+"%##'")&+%!&!&#&''")+&$*+&"(#$$'!%(&%(#"$!"#))#$)&$)#!#$&#$#*&&*+"+!*&($'#'"!##**($&'+%""$()'"'+#*'"*!$*+*#*$($%'+*#'!&&()&)$$#!!!%)+!#"*)"'%$)"'(('%((!%)!%+"%)&%*&%&*&#*&*+("$%#+
@r424
AGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCNTAAACGAAGCATATGCGCCGCCTGAACCACCAGGCTATATCTGCCANTCATTGTTGTGAGTGTGGCGATCCGATCGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGNAANACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAAGCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCG
+
'A-!=/7*==%6B$>',7F!*A)E!,=0A03,EC-8$H%70H2DB7,6+.BF-DG!F6(48>)F'C%C%!B:-1FD+$/!A"3;<6DH1=C=:1&:!87G?,53>(G/5<2AH0/9B*8'D?H&G7)&A@C-@D8/9H-(#)DC42G+!.B09=<)D:/'C980D?.H<4&!8BE+$H63F'5)!-)G,<6$*$=98/)>H3B-'2+<2#'E%#<B1DHB+!.E-76AD4/6C.&%@9ACD:CC7)7@;C/6823B,%7G2D524A$H10F+6=(!&,543,110D6>8%,890D'G7&"%9EB-77.FF!)<$$DB3>8'8E$(8:@H"+D9$"@1*(3>%:$F4A4$DE6:>C'?",&B:,?2+<581@@-!!7>E'<G71H309EB'20$5E4BC&:A.D":'>E1$G8'A28?4A"=8D6;',9;D4(!*DF(#,GBE>0%DH=06%@E&@B=3#;H9$:G=;F'@#*!(-5+H:.1($F8)%-4
@r425
AGNNCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACCNAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGNGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCCGACCGGCTGGATTGGTGAAATTGNCGCGTATTA
+
)$#$+&'))$+$%$"'*#&#)(*'&)*!"&$"&&!+$!&(!%"*#*#!&!$"$&+$)'&+"$"%")'%"*%$"+!$#%#)"!*)$"&)*!$!)*()()*)#$)*!*$($+%'(+$!))'"%#()!!!"$!%&(#++$#'$#(#%'*&$$+$$#%$++#"''*($'*!#")+)&+%!+*+*'!)%&)%%"%&$#))%!*)!'%$%)'*"++"(!&&*)+*&$"("!#&&%""%*"&%&*#)*')(**&+$+&!#+"$+#)
@r426
CGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCNGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACNTGTTGTTGGTTGCACTGCTGAGCTGNACTATCCCCTTTNTCTTTGT
+
@2-(C*BH*++:H:</57<-3)<3E4B*FA-/)5G&G;(B:+/4'#*''#"/(4@657=&4"%##'1:E+A4&*'H>#>405.?(=!HC+@)CA1=1?C*68D43.5:-;!.%><,+08!>G*&/.!93B%,16%4<EG:G.7)H',G1AE.".B646?.8.>02*D'87;,HH1@H$C2:B0&-#)FB1A)H>D#($+<39.(71>;H1*5>116#D<D4$3%%;;$,8:!)?A?:8/?8=3B-@F39,88-G:#E2/$%3%BE'4;+)$D5C-#<7>)?@#9D1!/BH#?H.:3?<642-B!3D*B#/82@8:+F@88
@r427
GAANCGGTGGGCTTNTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCANCNGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTTACGGTTTTCCACNATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACNCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAACGTCCTCCGGCGCAGA
+
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
@r428
CNTCNNGTNNTNCNNTNAGGNNNGNNTNGNCGGGAGNAGNNTTCNCNNTNGNCTTGCNGTCACCNATGANNNCCNCANCATGAGNNTTNCTNCCGNNNNNGNANATTANATTANNNNCNNNGNNNNNGCCNNANNNGGANCTTNNNCNANNAGNGAANANNTCANCTNCTNNANTGTNNTNGACCNNGNNTNNANTCNNNTNTNCNNNTTNNGNTNANGCTNTNGCNTNNGNNGNNNNCNCNCCACANCTNNNGATNNCNTTNAGNNGCNTTAGGNGNCNNTGNCTNCNTNNGNTNCCNNCACGNGCNCCGTATNANNACCCTCCANNTGTGTCTGNTNTTCANNGGCANNTNNANTGTTTNGNANGNATTTTNNNNANTNNCANCGNCGNNANNCNNNNTCNTNCNATNTNNNTNNNTNGCANTTNTGTNTNGNNGACNANNNNNGGTTGTNTNCANCNNNNNANTCNTNTNNNGCATN
+
#!#$"!#!""$"$"$"!""$##!"$!#!$"$#$$"#""$!#!$"!!#$"!!#"$#!#$#"$$$""$#$#!"!#!$##!#$!!$###$!"$#!$"$#"#!""$$"$!"#!"##!"#"#$$!!$"#""!$#!##$"$$""$"#"$!"!#$!!!#"#"$$#"#"#!"$$#"$#!!!"#$$"$#$"#!#!"#"!$$$$"#!$""$"$$$!"!!$#!#!#!$#"$#!$!"#"#$#!#$"$""!"!"$#$!#"!!$!!#####!#$$#$!$"#"#!!"!""$#""!$#""!""""$##$#$###!!!$#"#"$$#$"#$"!"$"$$"##!##$#!!$#$""$#"!#"##""#!##!!$!$!$$$$"##$!$!!"$"$$$!!"#"$!!$#$""""#"#$!"!$!$#$!###!""!$""!!!#$!$#"##"!!!!$"$!!$!"!"$#"$!"!!$#"##!!""##"!#"!$""#!""!$$#!"""!#"$
@r429
TACCGTTTCANTAGGTCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAGGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGTTTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCCAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTNATACCAATGACNNACACGGTGGCTTTTGTTTTATCCGCAGACACCTCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGNCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCNCCGTGCGGGTGATCACTTCCTTCGCCGTCACNGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGANTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGNCCCTGCTCTCCGGGCATGCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCNGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTNAACTTTTGCCA
+
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
@r430
AGGGAAGTCATNAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTANTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGNCTGGATGCAGAAAGGTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAANCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCANTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCTAGATGGGGAGACAGG
+
7B3>;6/"4(),H>:=:>"1;68G(08H&G,F2882:>AF1B(;"GHBG1'=+&>2)+""%@+F(D,G&6;@333"847E0?B+".<E%*/6##-A>9%!9A*>>@5%3+(%=,"@52B)$7<5689:"6#8C@?A3%F1D'':$)D>94:@*-#A2)1>'34DE>563/+=#>1*BA&-:,;8<4B17.6.5B@-*7-H16>-D"D%=D418A(586>G%'$"=%%9'!$B..F"$$.HCD-$@*-F:6?'%9"3.F;E+<<;?+@#61,=*.*1%*+&6H8*#8'G4@)'H?A.!E%)F.3D>C'82%+7B!#'1.8*,6(12;'<255*3--E?3!/5#G&F/&'&ED"!6=0,&?"6(F;*BG(6/B!+0F/.?>F/?="-69FA321%B621<5DC)$06<!+CD%"G7!3H%'AH$2..%-(&55=6E>9!#
@r431
AACAACATGCCGGAACAGTACGACGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACTGGATCACCANGATGGAACAGGTTAACGCAGGAATGCNCGTAGCCCGTNGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGNGCCGGGAAGAAGCATCCGTTACAGCCGNACTGCCAAANGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGAT
+
7EE?@?#:')/*EG8@8)(;0&)G/,C(+G&'=49>:B28E2H/*&-H(0;D97*',,3C5":'6A+#@D!A-;(40$.,FHE:92.30937H#&G>G@<.H8=&4+H'%2:A;,HH>2CF769:"9:8:A*4+6/9*#467?0)8$$H2D&506=B485G9F'.E'::2%$/=<5EC=4F9>/24$6D*--99<E3)%&9*C'H(/F@6?;%D*=CC1-;E&;'&E7?:E+=9.)+'$!'D=1<HD>73F=$8?F*=H2G?=/<482)$5.;/:-C69:@EH61"<>%+%+15(B22@.-$15%?9&409*7A&H*(-5A=@'6'*1:<(F-"1.<$H/3E/@">E4:'4H4>-172103.2%A,
@r432
TGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCNCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGNAAGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACNGGAAAATCCTGCAGGCGGATTACAACACGCTGATGG
+
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
@r433
TTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTNATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGACTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTG
+
(<H+FG>H;,$A>B8-&GG.D(.-5B;B?!31%-;HG).6F"48$B2!0.C4)>6?031./4?E*-!!.62=A9)'92?$);89FG/*D(%,:9D3'EB('C@?"5=3;9?0"$B&=?836!,$/A)%*3<<>5E+=*8@B('%@'+&E@F0<41#*D4#%1'FC2>+".!2B99C@>5:?F%7F7C-!"2#=)6=7&B<G)(02&178EE2,9F:G<62H4-+24'6:/G.@4/8""#."63/-!GA25G5)3'$C"1+F)+A%0@/+6(40H-&'+B8/!;&FGE0<-4G)'=&(4.;#7-&8.1<<3.(4$8>%A2@&79"77(0B7F#A&D!8;BF?8.8"90?G3+'<6H<BDC@E?>>)A'%C'.'H4$":%A+/%*,(?4118)'&D&1F640D!+>*5:$:7)2;:HF(
@r434
ACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATNGGTCGCTGATGCACAATGTTTTATGTGAAACCGCC
+
+(%#!*$!#"$''#("&*((!"#(*!(#)#+("++$'("""#+$"*#)!!)"*$!%)'*+)&'*)!#)"''&&$'*%!+&*("!)&((+!)%!*'*#"'&%')*)*+#'%"%%'&!#)(*#
@r435
TTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGNGTGGCCAGTGCCCGGATGGNTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGNCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCACGGCTGTGCCGCTGACAACGGC
+
B18%9*>:#?31<=03/H3H%9D!(*"!(@,9AB+7?D5D#C2D"!6E<553A>#1;3H1.A"+A-!>7?>AD.BD":5(D8@%0=3@'E-5&&&.<1!/52/(1:'!C9:@7&:$$816-51*;0+::0:&..A8C"/=C@H028)HB:7(#,>1/CD.!8=002*.A'*A:*2FF:@2F!H@,'8=C7*E64G=.9)>?7*&(+,9"!!F.=.B8(*H%%!6H-3!<=D?,586?*7<"?+0,G3E4->11E#1+/3@!)=;-E109(?48B3B3'F==7%*:%:35?!8?8044A15-,.$D&))."!?@?'!,AE$%F&?B/4..8<'*H8$;99",1:7B9::E'>/79@8>=33:DAG4!-+?'
@r436
TGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGNCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGCTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGG
+
G,9.!F&="#8/G?(#37FH7BD/8E%?(12&H&#1=&D/@25HHG#*1,+2C3,87-&/+%8H;B!3<#B"E?3H-792E9"F=4C#;F94*A55,8B';D$81=%!'-FB'>$1'8D*40("F+B:D+B@@AB7&BH?6+*0.8+"777%:#&;(;."6>*2%B&"#)>HB2H'+:*:1G<:5,A6?@826)43:=;327*B$HE+4#BC=%1=0"3:H!6&)5&C097)C3!6.B42E,&2FB4!0#89)HDB96#F%C$12>8$FH)#@9-F:H/
@r437
GTGACATCTNGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTAT
+
BB*&.AB=B'$FD;4>>A,C.(2,4G!A%;(!9H6'250.9H!A8#D).69+@B@H<%)&)-$>,5(D3G4=
@r438
CATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGNTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCNGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACCCAGCCCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAANACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGANCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTTAAANTGCTGAATTTCGCGTCGCCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAAT
+
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
@r439
NCAANAGGCNACAGNNTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGANAAACCGTTACCCCATTGA
+
$&)'!%%)'%&#'*!!*)%+&!!#$(**&%&")"+*$(&%+*!)"+)+)%%"+"&"%)'*$'&*%)%%#$)#+#$+%($!)$!*!'(*!+!)#+#+)$&!")"%(("&+!+++!($)&&$)###+
@r440
ATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATNAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATNCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGNACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAAT
+
H6;#!09#8)==BA*E+4B8?*<78*:=7$=.8>&(8C.*407.4$9(FAC<"A.=E='+4A-.F"B2?,@";718.&"H1G7<8=B1"@%C,9'5E"=H":%=9(984,0)4746=8=%,CE)"=+BE:-'D</CF<5A#88D47FD#,C.@-H=GD(DF-AAF244-+@"G%*'$52F4<4=&/6>F/.>0*F*%B?6:D93"'C;.B(F2")AH
@r441
ACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGNAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGG
+
1?;"0#..0$%E1/;"+!'!A*>%,GB,#73@E=<H)5:32D?;6(<C3B+&"B3.'2<B92C-.>=9B<G4!.&/%E38"=.5B%F<&8BDD*$:H>G8.AB-C/:H>0BH"-:)$'1+:8=9047*/&7<+E/<H*'$>4!0)ADA53!.#C!B$!E(88",33A;$E=5!*F#;&'
@r442
TCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCCTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAANTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTNATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATTGAATGGAAAGCATANATTATCCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGNCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCNATACGTTGCAGGTGGCTTTCANTCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCNCTTTCTACTCGTGATTTCGGTT
+
(+*$!#(%#+*&(+#$##)&+&*%!&&*(#%"!'$#++)&&*")%!*)(!*"&&+%(!($+!!'!)'+$(&'+$)!"#+'*)&+#%'"''+$#+'%$%!$)+*''%%#(+)%#("$%"#()"'!)"$%+$'+&#+&*"'&)+)""!#!(!"''&+!%#+)'$&+$+&)(!*'$%'!&$$&#)$*&&"!%('("*!('"''(&)*"++!+%&)#"($)&'!)%'$&(+&')+(&'%$%"(***(%#")""))"!%$+((+#'%"*+)**'*(()!#(&(+*+"'*+(&%+&("&+"%+)'%#'##)(%+!)')&#''+('#)!("*!#%'($"*&($%&+%((&&(&##)$#)$%%%*(&&)$""%(&)%")'*+#"*'+&(&%!(')+)(*)*")$"&*&'+")(*)*&!*&(#!&$*%)$$)!'""%*"*%%***%(&"+$)!'!%&%"%)$)!")%'**+&"!'("&")%#"('&%#&))#&$(!!%%+'+(#**)%$&'#$%+#++$)%##"*$%%($$+&+(#"%'$$!"!%&##''!#%&&+#%!%$&++%#$''!$#$"')%)+)&#'')$&+(""*)''&'*&&""%")*)%!%"&!#$$#)#%"$+%"&'*(('#"#*&%")("+&$++!#'!*"%&")*#)')'*&
@r443
ATTTTCCGGGACGTATGACGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACNAACTTT
+
#B=%:3F6@@F<E8+$6.DE4:5@(2@-B;B%(-9?)4;:*)$$/0$'>E%6<E2"/;9>C$!BH"H/H),=H/,HD':,4?*2(5.-CE+?"49%!EG0=9$?B/.#H-"G/;1,=>6%"G'8)4:A492*8(9D#&5(1>2HEH>%+G)&G79EF=&%61<B*@1<0@3#8C)>9(/('"/!=2=:9-B&9BA,AE(#'(/A=6A
@r444
CANNACAAATGACAAGAGTCTGGTTCAGNAGATAAANCGCTC
+
*)#++"$')%&+&(+#$$(*(#&*#&&+++#%&%*)"&#(*)
@r445
GTGACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCANCAGGCAGGCGTGACAGCCAGCAAACCAAAACTC
+
%&!+($"!#&%*!**&&'#$)&'%*)"'"$%*')&(!"$(*(!%#')(!!'%%"()%*&+"''('(*'*)#"!$%)*)"+)!
@r446
TTCTAACTTGNCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGAC
+
@4E4>$A<*/D3A,(F&.B3548(6".EFBA%."3>*2AF<5859?+#'0)68)#FH+H6!88"+23>8<&F#/0!0>>,-%2A*:@6#D;<<'8;#F+458)D"5;+AH2+#25!G;#B$D>4=:0(,1A/:8(4E"=')#(7F-F!0G)"&0H&D089%0'#:BF>&G&G$48#.($G"4EC/3.43+7;@=ABB*ED/#(!41C$A-@.>.C".-H7)-;D4!>;81;)3$<$+H6";#@D*=&A/'3,#5+-#7-E,;2EEF.@?'&=;E.68+*!>3
@r447
ATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTTCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTANACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATAAGCTNACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAAT
+
#*8>-*C+?D1,-B'%#6?*&8F.':G),7-,8E-(,,+.!91=;*,7A-@B=A61448='4DCD>+:?DG%#>G#*&-"?:DF04C>@=40H8G8??.9((!:)$+H!A#+13+F&AG2H'6,*D?&7F<25#E$".$6'*#<@(+0%-D5C:2@GFC&?,-!%6.$%+$'86G)H::C5.$#?39E;11?&G.>FB?!+5!&E=,#<-=*4G;:D"AE)#!A&;=3'$H79-$FDD'H(*H&'7D&?1D5-'7-.%:5FF0&!CGH31@77C%HC6>F/B&0=<64B;,;>3*=5/(0GB*?(>#A#?>6/1$'$#/+<E/*@):3H#5D%@F=4*7CF&7(G;7:>*'+,=H'H979EAD
@r448
TANNGCTATAGGNGTACGCGCTNAACCCTGTGTGNATCGTTTTAATTATTCCCNGACACTCCCGCAGAGAAGTTCCCCGTC
+
*#%!%$!&)'!&!+!())%&!'+$!"#"!%!***$!&%%#$%'%+%$%#%($(%&)*')!*#))*%(&##*&#*+#*#(!$
@r449
ATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAACTGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTNGCTCCGGAAGTTCACGCTAAAGCACT
+
66?#)G2?2)EE3"2(C)>@</>/>$C#/6(C.,3>E9"<#'*>3B'?@3F":A?$:$<=3;,B@<DD80("'3/?(62FD'@=")=3<1F9%"./#06+AD"F%C*?2G$7"6)&*&G;H@416+,=H%B(7?<B2><>
@r450
NNGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCNGAGTGTTA
+
!!=(H23;,*#G2;1?(+63:$)4)?C%$:=#,&+<%@*G30&??
@r451
CTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGANGGATACGCGACAGCAAGTTTTGGGTAGGCNGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGAT
+
+??8>?+=%3-0%G'(G52F)@((G#4$-*09$%4D*1G/81'3:.4"FC/,<5780@?&?E.F5.'B&@&5A*22.)!/.@--6%)34#&*/3/'?,&A7-8/<B4G.D;H9=;?49'$,6'?*D6F-(/F;-)D&3C)4<=%"+=='"'AF':&=-#'F7*8"'-=021-A&.;",#4/@$2<%AD4.",&>'5G7-45"9353
@r452
NGCACCTGGGCCATGTAAGCTGANTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTG
+
"48<,>"6';#*1(*C3<8)"2E4&F+E'E6,#))5A310"=0..!8<<H!7C4@FB9'#AC:&H$G;B'@@,A)(/220%'?E(%,?->$C9*,="5,F/C
@r453
ANTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGNGGCTCGATGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAANCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGNCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGNTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATNGCTTAAAAAGCGTGC
+
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
@r454
TTCTCCCGTANTGCTGACATGCCAGCGGGTCGNGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTG
+
)+)"+(*(&$('&%)%*)(($"$%!##'')("+!%%&$(!"'#'+#$"'$!#*"$")##)''!*)(&$%&("!*"!(&'+(!*%+)#%%'$%+'!#+***"!+&%$('$("(!#(%+)#!+#$$##%&%"!"(+(#''"+('*%+%#'+)*#*)+)
@r455
CCACACCCTGCTTGCTGAGGTTTGCACCGGTGTNGCTCCGGA
+
B"("?F77'%F8"6%FB1$;70D3-8?><#-+B0,20&-A7&
@r456
NACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATNTTTACTATCTAGCCACAG
+
#G<>38+,@47',6:BH642<+G7D72C1*@:C0!.+&:%?--H/4"1((CG9$>+><,>E#G:)#.$9,
@r457
GGCCAGCAGATGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCACTAAGGANGGGTCTGNCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGNGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGNCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCNACTCGCGCAGCAAAATCAGAGGTAA
+
+&67D#=&>4%A;7:54=%2"=E,8H$8@>6A7")6A1:C5?34)"@43$:&%A5*)E@(/;:.3*?H%CE.2E*GEB@#FA8G771B;=3&A@*F:B437%/2-/GCD@F&*B5>@)1+"*?<92;,!G-;65"C&#>=B;$94?3@)3#GB*&<B;(+/1*)DH*'16'7%1B3,'6#+@."$?-=47*1"0%5&,B;.,2(8&;&6.=2",9/E.%)A?G()@=+C$.B?2)93C#&'>?A27?;C:6D%>E2G10A9/E-'#
@r458
AGATAACCANCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGNCTTTGGGGTGTGTGTTACGAAACGAAGGATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAG
+
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
@r459
ATGGGAACCAAAGGATATTCAGACGCGAATGCATGTTCTGAAGCCATTTATCGATATGGNAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAG
+
E"4?":8+G/DAC):.'+C?>3056A5E%+*.7G)'$#=<<)78"/>-CA!F$&@HA>;D#!**/FC-14&C@A3%@710'3E;FA,42(003:#=+%=(4AF8F%=/*)@B+G$E78C0)(<H"&A!77#CC7A(1B'96A89:4,*84+%H?D@F-D77305AC56=71$>B)3@*!>E'60A&
@r460
CTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGNTAATTCCGTTACGTTACATTCATGGCTTGTTCGATACNAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCACTAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCNGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTANGGCTGACGAATACCTGAAAATTTATCAAGGAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTNCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGTCTACCGTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGNTGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGANTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACAT
+
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
@r461
GGTTANTGCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAA
+
)&)*!$#$+%'%&$"+%!(+###"&+!#&%('"*!!$&(*)%$%#!$)%%+*&+!'%'%))
@r462
CGCCAAATAAACAAATACTCAGCTTTACAATATACTTGCAGAACGTTATTTCATACAACGNTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCNTCCTGAAGCGGCGCAATATGCTCACTGGCTACCTG
+
GC=2*G#$5/0-C2>A><;&D+85>&FF.1$5<CBB7*)$))-;#,+1-.<C(/.>#@;-,'."8A17;A7G:370+H.;,56+;B>=>06@2=6:@),D3G4)H,$#39.*;50F5ED.82?BB2'4A3E@83,.:D+@"H*7)6,;%:@.?&43$2BD-#:4"9A/;)!+5*3950A>?42/AC?F-7.7?((E=#?.?(0#16;=@!CB+<9F*)=88BC/2G;?C'='+A:.!)D)6B3)".C9+-E=80C<H)
@r463
CNNCACAGCCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCTCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCATACCCTGTTTCTCCGCAGCACCGTANTTACTGTAAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTC
+
!!'+"#++"$('%)%+$(!&*#)#!'%(*&'+*%*+""*+'&*%((&*#)&$&%%$+"&'*##"%#"&(")%+(%$"%$)+'$!+%('(#(&(%)#('("%''+#""*!(+(")!)*#)++$$&(#)"!$!&&##+'($!*$%"(!+$("&)!!%*&#%+'((#$((#$"#&)((&)*&#+'"%(()$"("&%!#(%*!'(!&'%+&"+(&+*$#&*!*'+)()$$$"*%"&%$"$"&%"+#)'#"%&'*"!'")'$&*'$&!%+$#(*($'('&+#&'#**(#&%(#($&!$$"%*)%'(+"")'&'%$#%&('&)"+('('%+"###&%)*!")%)#')!+%'+)"$$$!!*+))$+"%#'$&&''(&(!(#!(&&+#(#(&+)%'!%('"**%!%%!%%%#'%+"($
@r464
ACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTTAACTATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCCTTNTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCNTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGNTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAACACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCANTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTG
+
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
@r465
GGCATCACCTTTAATTGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCAT
+
E:+61+@)<)4/0:BE>>6?.G@8<,A$@C)<'2)8,+C.>0D$%6+B847H/62:#&0,$(",$<
@r466
CGTTAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGANGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAACGGATANTAATACTGAGACTGAGATCAAGCAAAAGCATGCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTT
+
A-%88CA::431%.;.E#;?-54=#5"33:@==F23-68A!41;+D+A>7;%E#@/G.#E;5;&''=G#.@)F278'.!<6D>8EHAE1*2&:*%$%'-8"@#;5&.1D.0CGFA,#"!&+AF!2?)<F(8-$).8>FH9%A!6.6HD9$%E1#>D0",,8$:GB=.B#)%H%4(E8CB3GA"A@#=FHE@6,(G,@D+@)"9#8-G&E-C$$2$AAD'"D4%$7?">72/(&G4!%>D0,,!?@-0/'G7.8!#*!
@r467
TGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTNGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACNCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAA
+
CH0B81$#E9F+11-1,G!%;)+3@4%'G8!196%BD)1><;F0>D'$4<7B.F,.0F'9=*E/:2C%36!91"=*$@@>32,0#6C16E#!//%;*&G7!,$>3H<2%704;?3?%)<<=>5?,."F29$D7GCCFC*#-@.%667$D$-HB.=--B7%%<&>,(0;*4.:)<FC00:=@:5&4F./3(2!B,%E5$>;?F(%?BC65"=/,+*%()B/!D<<19,:"&G.!B+,+232"H>&?5DB96245'
@r468
CTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTNTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGNCCAATATCCAGCACCGCATCCCACATGGC
+
09G270#3C!,'"<A)4.-=*&=7@E2+'>%!)(AC-85G9&B=HE6B%<30/4<5C&%4.B@9H4??,,F(*8;92;54$0)?6B#$*-)74+/:+"?(/B<==>8<<C&9@:0@D(="8-5H2C0=$D;@22G*>E'8"17$>3783%>7<9$?9@-50?(>9=9BF6G+#'451)#<)09ABA*4D->94BF-GE:)$5E06420/CF,:07GA16<72=5>*<,(1:'7E1.2
@r469
AACAGAACTGCTGGAAACGCAGACCGTGGATTTCAACGTCGGCGCAGAAGGGCTTCGNCATGTACCGGGCGATTTTATTGAAATCTGCGATGATGACAATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGGACAGCCAGACCCGGACGCTGACACNCGAGCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGNTCAGTCCGTCACCGACGGCGNGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTG
+
@.5B80,E.-EE@#@4E5F@&CD(.#6$>>;?042#)G)G$>@C:8*%,96<3F"A+4%,(9@@708-8<"FF501=0G@=19G)294E%->E5%B>:,?H$3!D7,2.)!$.HH""'%?%3E>/?4E%&F!5$%#%"!:=2.29G<5/F:'=,HF%=E!2E3!&@<%,2;.A:+DC4)+?F*9&8E>->:*&8,E6"=).$(<)E7("%/94>$;40%G*=)5'02//*(@'A!F:>6AG/905HH,H<0.?9$//#F<1E$:@!"-.4%*>8GGF?;@"0G/E:F17#29)+9#:;CA),B%@-%#G@0#<+F=58?G"=):5
@r470
NGCGCTGNGTTNTGCGGAAACCTANCATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACNGGCCACGGCTTCTGACTCTCNTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCNGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTNCACACAAGGTATCGGGGAAATACGGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGNGGATTATNGCCGTAGGGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGNGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGATTTATTGAATAAAATTGGGTAAATTTGACTCANCGATGGGTTAATTCGCTCGTTGTGGTAGTGAGNTGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCNACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACTGTTTCGGTTTATATCTGCACAACANGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGGCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAG
+
('(#)*&&*('")("+$&))&(+$#'!#%(+&'+'%&)%$)"$'((#(()$(%"%'&*(""&*$'#*('+(%%%!!"&*+&)!+%#")&*#(&+)&($&))("#&%$))$)$!!*!*"$"!&$!**(!*)!+&!$%+**%(#"%+(%%)%*&'(''#!#&*(+"'"&*#$$%#&##$)!%$!*''#""(*)##!#')&'$"%(&)"(($!+*!'#%*(!%+&(+$""''"#&+"#!)'")!'+(!'"(*($*)&($")+""&'!%("'+("!)!++)+)$(!%+"&+"'*)''"&!''%$'#*!"$&$'%('!**%'!("%#*''&''&#+#+%$'&)'%#%'"")+(&&''!&((#"$&$"&+++$"#''!!"+(*)'!&)"+&$*%##(")&!#"+&!*&'"*+*%)+(&#('*()$#%$#+%#(!"**#"+%'*)+(##!%(+#!%*%$!'!""&#%(*%(*#(("+)(##++!'")$*()($+"'"'!+"$*&*((*("'+$*"''&')*()#+"&+%$#&%"!(((()'&""%"+)!(*!#"&"*'$*)*+)#)")*!+'"#+""+'&&)###''"!!!(*('+$#&**$("+"*"*$&()"()%"*+"*%&*+$)("*!'*")(!+)!*!$%*+*"''"%'*)!!#')#)+))'#"($&#$(+!%+*%)&$!)''"*'(!&&#(###*+##$#*($%+%#"(%'#(("*#(&%'%*$+*'&#(%#!%#$'*#+&"%$+&&(&+#%+!$!''#&&!%(##""*'$'&"("#&%!')"*!+$!#&*%!&"'!##&""'*)$+'"&$'%'$%)!'+'"'!(*'&!#(&"$&*%$'+*%+%%'&%$&)###%!*)*')%+)"**)(#)"#""#)&#*($#%')))$+"$(!!&#)(&!%+(*#+(*%)'!$#%)*&!#$"""+$(%#&(%(%'"''*")+&*%+$!!!%$'%$%+&#!#&"'!$$##'#*('*$%$"%$#""#%(#+"$')"*&%!$$&%%"+(+(*&*%####!$$'&((%")&'+&%&)$*'+*+$#'+(#%"!#!$&*%""&)*(()'#!!"+"+#*!%#$&"+*"!&%!#!)+#'''**$&%*(*))#&%$&++*+"+%*&('%
@r471
NCNTATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACNAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAAAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTG
+
&(&G#CE#9?.D8!9&@/*:52D69$"2,CA)')28=A.)8%0@FH!#8/60;;<$5@'7F9'2+H:$E(5/<@&F,('#A?>$1A'E-7&@<6;A;90&>*.5!C#8D0&(56!7"$)/;+=5G!6&!>)%+B(C"??-%7-810G)8E'-4118$%'1>$$4'8D1*;(D3!E/C?;>4)"DD?!3+>0A+@?E$,BEC1<@0-16@$<=/*0<470)7%CF*C%69')91&5#!D="D)68=15"AB3/.;67-:+?%5F%61>E8(3DA+%:<A2:(,>3$:.73(B.&%&C;$H>B<?2?61(6;!+>5@2&?A+/B!%8F6'@@3<)5.=ED.F.1B?;73B?<'+425E9=87'F=?@@G?("@64@00DEG:D6G)1#8!+?+>)7A4'8+.':B'(=D%CC4%1/186+@A7>5G&8*$$@#0"H'4FD2.>%)+'13".:B-@7>@H@&+!)=DA535D'BF>%-%+8%@?*-4E
@r472
ATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCNGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAAT
+
<?E/:%@?(:75B7505=GA$-$@4#FEEG(E<*FF4#H(3!=FB43F*(B2$&3D"-=E0B(%=4$E2:+),+48C$8)%8&;>#ACE;G*A'%C".7-#
@r473
GATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCAATCCCTGATNAGTTTCTTGAAGGTAATCTCATCACCCCCAAGTNTGGCTATGCAGAACTCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTNCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTC
+
:E".>?E3<=*/#!$60DD,3(1):C9#@:9F*;('5&&F".F#,</$9"468.#$2+$#7!:35*;=:G/,@)D=:").'BE-*/E%4(1#8=626!6<DC3>;;9:,C>=H65-E89D5!/4>%6G+91!CA*;/+AFBH2*0'4;6(+3@?8!@;F3(9.<>',,&4#$CG!=7A*/>6D6!AH4C*,&@):'G.==H$HB9'7)&5(*&%35(8=$/A-%(=@@-'%:7G#0F,8-$B/+&F>#-#%2&&88=%#/8*#785HD+$3!C%51A.CA%H)H/8,B30#'B<"0F;42$;3+B1&
@r474
ATNTACNNCCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTT
+
'*%!))'!%&+!()**$(&##+)+#+*%)"()%$!'&'""&!"+"$'('#'#"+++
@r475
NTAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGAC
+
"B##$D)&%7BBB2:9<C").*B3$%#0+?0E?F$?7?A<"!9'68"=;.+/#&6$,F;-!(*
@r476
GTNATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATAGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGNATTGCCGCAATTTCTTTTGTGG
+
**)*++"&$)!*$"%)(#'&'(")!$)"$(*")&%+())"#"#!%!+#"#&++"+*+))&#*!!*%(#!('!+#"))!+)')+*%#)&&(%*+("#'&%'!"')#$&)+&'$'%+&"'!+*"*))$"$*#)!*"*%(!&*(*(+)$"$(%(+)!++')$!"#"&&')#)#")$$!#"$*"((!!!%($%")#(***)#'+$'+!%+)#%'++&)+&++)"!'!''&!"
@r477
CTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCNAAGTTACGAACAAGAAAGCGTCGCGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGNATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGACCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGANGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGC
+
C".4!86>&A'.F*2!(9!?.$"6/%+,CH(.G%/".,6"1$@/!0*&/;+9<7+BC"@/)#E:#!#+B4!C>EEF1E,!F!-F'-9+8'..(D04C9!"9@F1*=(9,5(,./0%-9'H%!443=032G5/D062=#B&0*(-3/,8H;&.E<!C9:7<)+7&1#BE84D)BE@@9/8%"6<(13)G:HFF02BE$2@76H1+A=04BH%C:>A5*5-9%)3G!</80C(6#@;9,49&:E4')9%8(@181C6/?B/+=4/#9C26?2>8$;@%!%;&7%0%6!HB);>A9C2.36,4+94'+<4D979$#<2)?E6"@?8A'G)*7H>7#5'#H,/>;?#/$83$+HH3,=8)F8*2<B@"AB*("D<EAH2.98&&)CF0"6-"+!C&@8GD0!$G?'5(A82)3)G$%%"<?:--!4;0?"E>&H&0>3!&?')$*G>C/
@r478
ATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATCTGGTTGATCGTGGTGCANANAACGTTGAATGCCTGGANTTAATCACATTCCNCTGGTNCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCTTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTNAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTNCCCATAAAGCAGATGAACTTCCGTTTATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTNTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGNGGACACGTTCCTTTGGTCANACGCCAGCNGTGAAACCACT
+
(+"#"$"+!!!$$*$&!!'&%!)!!!+$&$+*%($#"!'((!&(&'"*++%+')'(")+(++&+"#+'###&%""#)$#'&!(*#+''$%$#"!))%!*#(+($())(((""%!)+*&%*)(*!%*&)!(*""&(*!#$*+$&(#+**$!&(#*$*#'**""#&&+')#"+$*)(('&+*"')%&*(*!'#**(+)&%'&))+'*)!(*%("%)*!)#(%*$&('()''&$)))!!&$)&$"$$$*#+*)&+%*#"&!%!"##"&"&('#%$&*%))+)')")'"*&%!+(+"%$!(')("*#(&%!!'#()+&+%!!''(+"+)#'"*)")*!$+&*'$)!#")'$+#"&$&)'")%!('*)%+))(&#$++*("&(#(*'"#+#%")('&*+*(#"(!$$!'')%%!'#"($'&()$&(*$')#*(&**%"+%'*$(%$+*$%##)#+"+%!#'&"')&!%!"&!)$
@r479
GTGCTGCGNAGAAACAGGGTCTGGAAATCACGCTGATTTACAGCGGCAGCCANAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCGACCCGCCAGATGTTTGCGCAGAAGGTGTCGACATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGNCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCGTGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCNGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCNCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACNGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACC
+
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
@r480
CTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACNGTCGGATAAGACGTGGACCTATANCCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCNCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACG
+
D?'7#*A%/F2*'"&>B(C;FA-62D;A:+54#!1H2+"9H,CH9#7="7H-.>D6+15B:A28D0"=="'/2E181*D90G:1'-55;:>8D,B!*$=!.>0<+C#@H>E+H8.H83!'F,C6C"=DB)6.391-B;16/0(@"@22,-75E+22;D6F5/=6,E85@:*8<*%%)(;E?C'B%AHA(=>DE>/"3
@r481
GAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCNTTCATATACCCGTGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCT
+
G#-=3*;FA"@7,!="'A70#@D488=-9>8<=F<4E$:G><',$5.G%HAG(2)):-24DH)BH?;6"!3CEE&1/@%,E@F@:.6GB2!%993&%?%,3/'#/--<C-9&":'C(1!)+5'?#$D2(#.F.#H+3<C%D!695
@r482
TCNAGTAAACANNNGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTNGGTTTTCAGGAACATCGCTGACTCTCNGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTNGCTTTTGTTTTATCCGCAGACANCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTNGAAGGCCACGGTTAGCGTGGTGCTCTGCNCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCAGGTTGCCNCTG
+
'""'%('%"#!&+++*+)!"&+*(&#&!!%$*")#&!&'+"++%%!'##()'%"#&!')#%!&$%#*'(!"&()$##!'#(##%!*)#*%"(#$!')##"%%%"'("$*(#+$!)!+%&&***%'*'($!%*'+'&'&"&%*"%%)!"!*"!!%#*&($&!))))'#%"!")'&'()*(%%#*")+$")(*!%#()$!$+!")%('()(&!)"&#!)("##(%"!*"#$#($*#%(&'&")*#'('&(()%&()())%"')))%!)%"''!'!+%()%&'""*+!"%%!#(+"*'('*(%*#+("$!%$*#"%)"$&&*%())+#"*#("(%*#'%')++")#(""(!)&++")+$##%($'!%''+(&""!#'%$(*)!)$"$&$++!+*))%+$()*)!))&#*''!##)(*$()
@r483
CCGCACCGCTGTCATTAATCTGCACACCGGCANGGCAGTTCCGGCTGTCGCCGGTATTGTTTGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTTTCCGGAAATGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTNCACCGTTNAATGCGTGCATGGCCACCCCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGACAGCGNCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCCGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCCCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCANATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGNTGCCACCCGTTTACCTGTCATCAGGTCATGCAGNGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCTTCATTCATACTCTCCGGATAGGGCACGGGCNTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACNAAGCAAATGCGCCGCCTGAACCACCAGNCTATATC
+
+(#&)"&&'&()+&+&+!'#((#)#"$+"%#("%&*#)$%('+"**))&$*#$((!+$$"$*))%&"(("*#))('+%"&)*+#+!($#"+'""+")%*&#!!+!$)%$'!+&&!+!#$'*)!!!(!()$"'$&'!')$!++$$)(*"'+&%%))&'"("#&"!*!*%#%&+$$+*&%#'#"'+%'!++++'"%&*$$%)#)#"'))+"$#)$"&')###*"$"+!($+$'+"$))!!**)&("($'""#&(#&('%*$++(#%!*&'#&(#+!(!)%(($""**#*%($!""###)('""$'+('+#)&!%+#"*#&&&*&&$$*(+$#(**#%$+%''$+$!%"&&!'(!)%++)()$!++%$("#+)#&#'+&*#*!*'+$#+&%'($%&("#*#*&&!!*"+#!*$$%!*!!'"&#*++%#'$$+((%)&!#%&*!!#*#*%+&"&"'+""*&#$%#)*+"+!("%$!)&&$(*"(**'&')*+($))#!%"*#!(($(%)()!++#%*$$"""$##*%+((('$!%")%)(+%&'$($)+'%&%")#('&$"*"*"(+%%%'*!&$&*&%&&"()*(&)'!!&"%)+!)&)'&('&!+&($"%$%($$*%#*'(#)%*)++!"'!%+%++)%!'#*'!%+*()'(!''$(%!#"%(%)!(%#&+&$+*!$&#&$'"*##))'!'%&&$"+)*&'$(*"$%#+*$##'$$+%!!!$'%#'!&++*'!+)%)+%(%$+%&%&!!%&%%&+$#(%+)%))&!#*'+%++#$'#"$&%!'$$)$%+&'(!"$)$)+)!!(&$&!'&!$##%#'#"%!!!*"#+**%$*#!$*+*%%++#'$(+"+$&+%$(""++"!#%+"&"'%!$"*$)+%$%(%(!+&!()$)!%#+$##(%&)"%#%*%#(+'$")+"+%+$#!+%)+("&&*!#"!#&#&$#&&!"&"('*+!)"&($%*!(%!$"+'%*##(*'$)*+($%$$(&*"&+'$(
@r484
CGACCCATCGTCTTTCTGATTTAATAATAGATGNTTCAGTTANATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATC
+
.C3>"/1HF+519C8.%,39@#$:=02F*A4#:5G0FG4@/EG%:#5G-9B!7B;8$4%,"+/E3..'-67E#,7+F?*D/A@;5#6:95*B>G+F4"?77;#H8+B'7:-C7E4GB9*4H079$C)"=<6B!9)#>C9("@7-B6!</7E(E8@.6#38-)"6>;@(#G9+/F1',*@8)C$0@0*@.)
@r485
NATTTANTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACCTTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATNATTNTTATACCAAATGTCATATCCTATAATCTGGTTTNTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATACAANCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCNATGGTTTTTTAGTCATAAAACTCTCCGTTTTGATAGGTTGCATGCTAGATGCTGATATAGTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATA
+
%)'#'(!++"%*#(++)+)%""+&+"!()%%#&(+'+#%+(!'"%&"+*'(**!"!%&*)*))&%"&&%#!%)!*)%!+!*)"+%#!!+#+*(+$(('&'''+*)***%"#&+((&&(%$%!*'(#)$))''**"**(+)'!)(%+&$#&"%!*(+$#('&&+)!)&#'"$"**)#"!(+$%*&#()"!++&&"'$%%&%)#!!)$*&%!$%"!!+%+%"###(%$!""#((%*#&#%*$%*!(%*&!!!!"(!)&**"$&)+%+&"(+)#'*($$%"())("''$*'&"&!(!$+)%")&*+()"+((!+#*%*)")*")"+")*$!+'%"%*&)!)))!%"+$""%"!+%)%&*%#)))(%%*&"!+##*"!#"('#%!)$)(+*($!&"$*#)$'#+")"$+#$)'!*(&%##!*'%$!$"$!&"&#(!*!$)+&+%)#!$%'!)(+#%*&$++!%!"+*)!%!(&"$+&&"#)+)#$"()&&#!$#!
@r486
TTTAGCGTTAACTTCCGGAGCCACACCGCTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAANTTCTGAAGTGGTGATGACGCCGAGCCGTAATTNGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTNACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTNTGCAGTGTATGCAGTATTTTCGACAACGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACNTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGNGAGTTTTGAATGGTTCGCGGCGGCATTCATCCA
+
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
@r487
GGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCNGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTAGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCAGCCGTTAACCGTCGCCGCTGAAAGGGGGATGGATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAG
+
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
@r488
GCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGNCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCANCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATNCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATC
+
/%>!)%17.;4H79)3(H)839:"7B'GG.$3$')0':C/*@2=(3;,B'!C.2?)AC%1,6C=D/8EG)7<416E/$"?(?#16&?06%&.E*;F3=E+=?/:;G434?/!")#/4"+>H:)FF/G.>@E10B.B)886$%>'42@4&!!59G:>7)"&A=.448E=-/*6H80((,9A?%>3CF4'$#5CF71;.C"%@2.!-D:%$?@C*F!8+$(24&0(@&6,+4141.%+5!2)7>;#E'H',%=.7-8BD)?+2>&14"E<(.D-G1>?EEF;<9&&@(*#-A;.4D+:G):F>*0$B'11EG"-1HF,AE'/00+>F(=>3/DF!>:8&0G-3!52!C.03.,2C>CA*8"B#E@/<@4:04B>B?+0@,5$7E%=CA(G@'E(!5=0=629DC
@r489
CCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAANCTGTTCCATCGGGGTGAACCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGNCGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGNACACACCGTTGCTGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCC
+
(+&)+')%'+#%%!$'+!%$%#!'*#&&&!+)''+')&'')!++(#%(&+$#$#*+!**")*&()%+$)+('+%"("!&%)'#!'+$)#)'))""*'**!)&)"''#*(*)+&(#(#)&&+%'"&!!*!*%#&'&$!+("(*"%+$(*!#"%'$(#&&&+&%'"&)!(('$#+''%!"""+"(+*"$&+#%!*$"&+$!&%&&(+#)##**(&#+#)%&+#+&($#'+")#'&'!%$)'"!)%+#&($!+%'!"&)$*'&)+("%&&$&+%%)(%'"%+"%)"$%"$&((''!"((%$)&)"'!!*'&*"##'%(%!#!&&)
@r490
TNTCACNCTCNNGNNNTCNNNCAGANNCTNGNAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTAGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGNCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCANCCTTCGTCCGTCTTTCTGTNCTGTTGCCACCCGTTTACCTGTCATCANGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGNTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATTCTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGNTCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGANGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAN
+
%!%#%&'!$'''"#)*(&"#!$%!(!"#!!%$+!%%#"&&#$)"##''*)"%*'+%&%$++*#+!+$)("*+)+)$!)%'!'"&)!'()#%($!*$"+"(+'"*$)&!!%$'(%%*"+"(%+("&&!*+*#("(((*$)!!#'#'"#$'+#'!"&)%'&&#'"($***)$'%!)+*+$$)%%!#!)!)*'!&$*$)+&*"+!)"!%('$('!)!")%'*"*#"$!*"+$!+$)&(&($#"#'+"))*$"''$'+#&"'+*&*#&&!*"()*"(&!"!')'#%%(***$+#*!!'%'&"&!!+'!'(#!#%)*%"%&)$*%*%#"%(+#("$*!'#!''"''"&''+!"''%(#$!!*$$$*%)$$%+(&"!!%+$%"($+((*!"''*$')#((++&#(!!%"+'&#%"!)!!'+#%!%&+'!"'#!*&(+!)!&"(%*$''+!)(+(!!&%#)+'$)+%"($%%+')(''''&)(+""!+$&*%+"+$*(#+$)+"'$))#'!)++"("#(!")!)*%"&#$)*)#'$%($($')(%($!*!!#"!'!!%'*("%+)&!"'()!%%"'#+$!($'$&'+!(*$+$$#*!&!"+&!"+)'##(+#()!')#$("**$#(%(!%!'(('!*#!+$+"%")!$'$$('""*"!$(!*(*$!#$$)))&$(+&""!+)#!!&"++&+)"+#)%(*'''&"&%)'("+#%&$&('+!!%$
@r491
GCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCANAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAA
+
&/(@#<)-&)E(:B%-.2,"',D39<*:90#2"B(*""+45B-0C7"0'F@$"..F)A39,8(-.#AB47-*=/<H52(+CD"0/.:?G:C2,DH(D;)")2(8<$$#5C5/'1>-*+:!<0==?/A)"6,+BDA7$:"0:;->@&H(//6)"H5C$DH@)*5/&8-F
@r492
CACGCCGCCAGCGGTGCANCGCCTGANCGCAGAAGTCACTGCAGACAGCGGGNAATATNAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCTGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGNTTGCCGCACCGGCAGCACCGTCGAGNATTNAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCAATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGNTTGCCGCCAATCGTATCGCATTTATTGACNCGGNAAACG
+
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
@r493
ATCGACAGTTTTCTTCTGCTCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTCCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATNGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTAATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGNACACAGGGTTTAGCGCGTACACGTNTTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGNTTTGTGTAGTG
+
,0-.2-!-DDA-;!-2C51.-:'<-1-+'CD99<-66H"8164?'):%7F%<+..(AF:B@;61G=HC2GD,0@;"-C)(EB'-,A;+BB%%@=#)@'6*'B/>08""8179<$3/$%5;D<$$C6<13#!7!5<>9:60'55->!50=,769.B0<:-'$=!@H;E1-)H!#+#77A53*45'<>A,!>A,%22"H+E%-@!!/*.FE?$0:42+G!1?GE3@!1#"7=8*A$CCA25-CH=B.!"-#FA;%*F>!1(C$AD%H>.C0"HE!C<)5!71+:-F;&-4;-F:;)F"*2<H-#55$,GC-!+%E:=H.%D,9B?;7#"#H==$FE4E31/EE1GEH&."63?,,A69#C<"H&64&?231,A*(AB//=D8#*4"3@F#'655>0E8<<1='@@-6*22%'!&$$++'',&7B.C@,%,HF:+8AF$&5$#1@>:F6(!'9C..AG&2$'.<?$>?3B=21#B>
@r494
CCATGATTGCAATCCNGATTGCTGCCTTGACGTTTCTAATCGGAANCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGNGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTAATTCATATATGCATCCTTGTTTTCCAACTATATNATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAANACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGNCGGTNATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAGGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACNGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAANCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGNGGCATAACATGCAGTNGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTACATATCCTCAATAGGGAATAATATAT
+
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
@r495
ATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGT
+
(C:)H%=/E1A:(-.+$.$FF&D(2FD#040E1(?$2(%(HA,31B-/61?*EB(>'?F+-&H*%.!;32--21%
@r496
CGCTGNGGNCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCNCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTA
+
:=7-<+A)B;%?*01@%91.%*9)*H,D84%$4B-HH.A%E@EA0;.<@!4+9F>!=0*??H&$@E&$3@25B80'/,/(>EH1D="+4G%>$:%A<$6,:*?#C0++/$("!3(,34)'
@r497
ACGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGTCGGGCNGTTTTCACGGTCATACCGGGGGTTTCTNCC
+
!;@'1=$#E53B9;4<3&3>E4B@(F%,*30'26#7@"1;"=4=092E$'42),3B3E5559)!#*,B?G"<F)F)
@r498
CGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCCGAANTGCAGGGTGAGATTGTGGCGCTGGCCCACAGCCACCCCGGTGGTCTGCC
+
D-(>$!7/-'?8>H;85<B1ED5.?.427D58,:>&5")D5-@(<84("2<-HG2/:+;;!:DF5)B48/@3*:"C+='&59H-D&A/&5'>2"H,C0&4>C*3$,G0.-&!0;%+F'G/D)H"?:80$(::=F4(0A23<68--.8)0,/2
@r499
CAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACGGGAATGATGGAAGGATGACCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATGTCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTNTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGNCTGTTGCTGGCTGCCCTTCCGAAT
+
6C*%G<C*-$'')A.70!E?"%:)F1H;=5,#$68)?.#!:=G?=3:?F82.7)?3.8?H.:@94&?CC@0?1,?=0:'2H)BBD";6F2,-4#.B73F)::/B)51&F*5G77298+3F$9A)&?B";#28602-,(H=(+2"HD!4'+;+="(H7428*GC3.A8!E4AA(/C)31)!:"-,A<;<E):F."0;(HC4H=>6$@FE<=G#?84.+(D<3@:)=-?H.AG*,2*!%,*1.'"$?9;#5B'#2(&(7#0C9)>A<#;%(6F/83?E93;685D97(6H(/F=EE31!</6@0',9FB&=44BEG-3(2"E)D-$'90%&3H6,A,3#+/D1B3?8$=6.$9*:!!;0"E>0*6?
@r500
TAGGACGGNTATCACATTCAAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACNTTTGAAGATCAAGCAGATAAATATATNTTTTGGCTTTATGCAGCTGACAGAGCCAAAATAACAANTGCCTATGGCTTCATTTGGATATCAGAGCTATGGCNCAGAAAAGCAAGCATCTACTCCAATAAAACAAT
+
!,6E31D+$6G<A4?*73%%=8(-8>E)*0:5!+,1'!43-,G:4G192!A9E:*C&,E'27=7(/>H;3H3<5&AB86-3DC%17'#;C*F9G/!</%>51&''2C+&6*A*88'F1">#%,E@5'E'9%-'&;&AB>BE.4&9:1+"-B8#?5BC39.4CF;-"6,%'8FE*.@)/*4F54HE.(9)A%/"455%*D2(-/
@r501
AGTTCAGCAAGATATCTGATTCCAGNCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTNCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTTCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAACCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGNCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACA
+
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
@r502
NGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGT
+
(@$%!;!61#-(,5EF107'AD+$0-5'=;7ACH$$68*,9?0"90$$*$%G)D1CH&5*D02(7/$8*/9<G08(<56#D.2'D+(-GC%=DFD3E*E38A'++.>@'H4:4FA8%)>$F-93!@,082>D7%/)@-8D-0D%81!#F24#F=229..D+$9+!">D'(0'-?,:.+58*H#7'(49D
@r503
ATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATT
+
/#DH(CCBE@*(/):D((G#?:,B-015<:F/&-'(=(;#F5EE*)%*97::,(,#E?7A
@r504
CAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCG
+
.>"(>A0F77!*+'$(C857=!A?88>#C&$=+,D28CA5<(
@r505
CATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCNGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGG
+
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
@r506
TTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCNGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGT
+
/G),E(:A)D4>'3*57.$H'%0HG-D<'A:"E+7"/:9/G%1=G;,3FD!#F=FE$">?C59>H;E%&1@B0F<4>)@BGC0(#<:#9+926CA1+?1&!B3&;GG8CG&70EH"3?@HG
@r507
TATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGAATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGNAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGCAAAAAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTNCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGANGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATC
+
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
@r508
CAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTANTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGNTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAANCATTGCTTANCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCNCTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGAGTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCNGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCC
+
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
@r509
GCNTTATNTTNTACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGAGAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGNAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCNTCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTNCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTNCCGGCGATAACCAGGTAANATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTANCCCGATGGTCTTCAATGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCAC
+
")"(()"##'!+&''!"%%&"$")$+%+$$"$(#('&)"+''(%*)$#'!((""!$$+$*#)*"'++""$&)&'#!!$+!*)((!")('$*&#)')$!+'+(('("%"!$)#+#!%**&$+!'**'**&)"(+$"+!($+!#"+%&*%*%)"*%#*&$"#!+!&$"(+$%&"#!!%#'+''"#'!(!#!'**%()$'!&#)+#%'!!')*##("&+!(*)*!*+#'%$!&+%")!%)!&%''$&(+("&!)''&%%"$+#*!!#+'&+&)&##)"()*"+!&'+*&!*#'"&"*$"#'!()(&*&"!'&''$)'''+(((*"'#&+*(*(%!!)##$#+)))+"%'#&!+$!%$#+*&(#*"*+!+$!&()&&%$$!')%'$&$!)%*#(%%)+"$&(%!$+)'$+&)!$(&!(*%$%&*$*)#("!)&%&+$!%#+&*$*!''+*%')$#&''()#')"#$"$"($(!')'++&"%)!(')+$)!
@r510
CAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCAT
+
)BE&/'$5)A/-!;&-="17%!+52-?=&E)34B5:FA/A2.,!0$E#*=:1.2?A&=/,**9C'A7(7=##BG+?H8-4'(/FC<9%$;3@.&@8B*4566G8'%@D073.2(
@r511
CTCCTTTTCCGCCACTACATTCCTNGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCG
+
<?7-*)&&?4#!"16!;E6")(>4F-+G;&6*<0&>#:+2(3G;':)4EB#E@'F!C(D>6>.<C%E#>F8>(19C.$C6="'7.@1-:(4??3;.A</')'$C'F9==7?$5;:3A>?.;?F$!/#!@$GA<+")E9/?)51.;@C950(,D(.2;AH9E#3.%)%0)D&@F5F-..)(G:<2>)/*?@:47$510&>C#+>(F!.'3")A(0<6219'D3&1,>8#&G,:<*8
@r512
NGNCCATCANNCCNCGTCAAATAATCAGTTATGACGCAGGTATCGTATTAATTGAGCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAGCCCGCAACATCCGCTTNCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAANGGNTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAANGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATCCANTTAATTACG
+
")"(#)#%#("%&*'($$+$&+##)&*&$%)$*)+%$($#%!$%#(+($)(*+'+#"(")'$!$$"'$&"#"+#+$+%+$"#'(%!!%+('%($(%#"%''&''*)')%&'"%!"(#)%#!&!#!&)&$"'((%*#&+*%+$%'*%%%)'#"'"())'+&!&+)((&+&#(#)')&$$!'&'(&+"#%"(**)("+%!"%%+*("&"(*'))+!)%#($&!'"#+%(++&**!*+'$++%+$"+$"")('*#*+*'&+$'+'+(+(+%)&&('"%+#!#&&&%**%&'")'!+%+)"&%(%"+*&#'*&+)*'##&*#*+)**!&%'$((''$%#$%%%)$(')*'*'$+%&&&'#)*$*#('()$&%&&&"#*!
@r513
TTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGNCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGNATTCTNAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGNAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCT
+
H"-,%3--<'1#003>7AE+8-&2(3,*E1<=4?FB2/!*<02E=,4C.19'E3:#7)513+6!A-CAHA:2,"=7G72?$;:D$./D>*CC-<H5CB/#0G<;6*:66$&;768=#6G<7?A??$G7.0"4AD!C;)):(F9F".B7CA=7G:E$&9+7/A0<*G5>A;6'%5!&:8/DD3&2$0+57.7-,-7&F1%'%@%:DBGH30H5'"#791*3=F,;<&@>;0<=!5.):?%D<35E#G$.@39>!1@F-F>!D,:*;6G=#1!+2B-5?>=8D(9,#/51+ED>A?%=C47*?+717G;71@8"%(;95*';-F>#;A!=BDH4)A2+*::!HG4)!G#-!()D%7=%.6<2;.F=0?(97
@r514
NTGACTTAAGAAGGTAGTAAANGTTAAATTCTCAAGAAACACGCA
+
%"*%(*#%&('*#&+(($+!+(&&&"$$')*%*%)&#'%%!+)&&
@r515
GAAGGAATAAGAAATACCGATATCGATACATCAGGAATATTNGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCG
+
@*1FG$>63%EC3)2B,45.=?B#G,&D0(&BF5F<FH"7D)H!4)BC;*0+//1,AB>.)2<HF8@-9)3<,/*24=%*
@r516
ACATGNCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTNATTANGAAACAGGAGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGG
+
79DCC&.E-:+GF03D/:6&1)9!013<;).#*0?(..BC"B&)A!:B0%H6D:9<-1<7-&G%A/<3$?-</?=.BF3"0A6;C&;4$E-)!AH9>*+-(4G?C*.'!9'"#98&!833C(D$C<H%:<8%C4H"D=8>9.H4%;?7?;94;6(1.D-0<#-!(0@BDB
@r517
GCGGTAAGCACGAACTCAGCCANAACGGCAAACAAAAGGCTATCAATTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGANGGAAATACTGAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCA
+
G1,77762<>9:9'-G3%0,F)HG#,G2>E/AA2:(!C!#*F2>!&GD!6!8C.-$)10,)651'*H!C44/GFB0!";1.#!9))?277$!>H-E%9/+=:"F3;+*&.<#'AC'+&:8;964?*,6;2G4G++(3;2:@CG&F;B020&FG;."##9'1@=7D;#G("'%/%'9E56#&D4<C(<*5%"<-#=#)C*0G.,8!>D70+5>!E5+>-D3=45-9,+8/*D5D!+1)#3'>C<A;,>=@$$DH:1A:>?2/@>#!D>-#?(2(%#58/&8$A#GG994(...5:%$3(#C83!026%D?:1@2*(;68(H/<*37,D<C37(274!/D777*B!,!4#??<)"?A1;"%:(*>DD%5<*?:9GC
@r518
GTNTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATNCAATGTTTTTGACGGTGTTTTCCNCGTTACCCGCAGCATTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGNATGGGNATGAGCACCGATAACAACCGGATGCTGGTGCGCAC
+
"$!)((++$##*""&*""'(%++(#*))$'!&("%("&+'*!*#+"%&)!!%++!%(&**$&#)'((*"*!&+))&(#$''!"'''*$+!#!"$)'%%%(!$"'+%#"*''*"+**+%&*$&"!%$"(*+%)#"%(#)+)+*#$+$#"$#"##()#()*&*
@r519
GGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTAT
+
F2BG0>4?C;DA&H>/:6/-0,6#D4<>8#,A)&FE/#A<.C"$3F?7;72.D"+%,F9D$4FB#BBFA$3%
@r520
GCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGNGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCANAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCNTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTNCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAG
+
4).+66.6<>!E*,!9:C/78&$@975EE#F58G?,.<5D2";''+,1)=-&,2$=>@,B&8>?>CD%%<$94B+.&5:#*C$#4>-(3$;;D/2-*=5!6B5?@>2$E?+,H$2B=+*#$F7303%!&8F&<9'#D38!1*5,()<!'@-:1A"G9#60??C*H6690!22"9,5:-D4(+00?):;$F,%A(1A#5&&;B;&&$;:8"!!(/.1??7?8:?""HHH"B>25>51;==((D.":>H3!.@"@;!&1,,?0:3+/@:$2?,4.0/FF#10A7A9!8:F&,H@?G"4.CDC%5+'@15(&!/1BH96E$2D?7@>!-B7?00;GD<E=/1'6?%?5F!1)!''*9$#&B10<:8+49)&.1&F'>7!>F-=2!D347B2>"54@%2D8(:3+;!;&99#(:1+5;;-.),:'H92$56%;0;+80%>E9=1>:#-<E=&*.?C(#%@4!?A.<?+F'9@0,G4A3>A$HDH3#*?53E'AA3/&"+A+%A3E+*H;@9)8@8)B=*>7E8@5+)?:514/E?D'7;.28":18)0&<)%/,(*/"/+:<G)5'BHE)7162-1"+B4F;3/631=4GD;@64A3,@49G.B9'AH=C.*##4,0H01+$%,1"+&@A@AH3#&6%-/5?'<;@>3.$#4G%C;89E010E6.AD%3&$?>G!!DHG,%0HHE'-8/F8(;F7HD")!?*B=!&90B-G51$?83F+(1BGD7=3"D4<0@2+=?D&-6.D32=E+>//.D2@4)16/=CG&>EGG)3>D#&A.B101A.1F0,$DF'/?:!(;0$9DFF!67%#:3B82A$C:/H%<,;2F>B1">C6:AE$:4*?946@5:=./?;D2@&!068:.<!80=0"@A(#55G-<0,)2=D/*42"95.=!9:/;+,@>0(;&!@&3.H5.
@r521
TTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGC
+
F80+"?+;;)-)G:BEE;(!/;HBG.1.DD8?B46AE9*4E'/%6H?6+7-148,1)E<!0D<FFA29D""B+561:CC9HE))7:8@.0-<?&/*8$8,E5@15G#/@></!362.2E;5',F?G8!<$#A@8-+F=;=1)C?B;5)#E;==2;2?-16*<)=G(H<<'C>7E6&=!C2:407*G$&>E&<H:D'%0G'+FE,
@r522
NCACCATTGCCTGCTTAAGCAGANTTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAA
+
"3C@@7,*&4'B:%1?6GH!,@,,713:=0;>3&26HG1.*1-9D&7<(B#2E,G";&-B/$<-/>4="3'A36E7G-<466*GG&D:6E*=*11*/223D:42H;<,:C%E3/@./D8%
@r523
CGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCNCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTANGCTGGTCCTGTCCAGANCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCNCACTGGTTACGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCC
+
<'+*1#880@4B@'C9&5@/60(B(CB6>E+'9)$7(:@@&4'*B1D!>:053%-&.D#=A&<E.8<0$B=G>7+72E05@H=G*C7E<F65($HE,+DH%<HC.@@)?:8<.D(2.)36A:6%F8*.*<'6/9'48$7!2*-H2#2'-E?A>E":A,!,8D0,4)"E#;"$=?@*?$=#0=:-AB1A)$A,>A;C+.G"E>0&2.B=6!0A2.6FHB$A&<#8?BG#2"#9#.3%+.B*,@5B@G9)(CA,;F):"?;>H@3&1CD3.4!:;C@B"F
@r524
GAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCGTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATGGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTGGCGCGACCTCCTGCCACCCNCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTGGGGTTGTGCTGTTGCTGGGCGGCGATGACGCNTGTACGCATTTGGTGATCCGGTTCTGCTTCCNGTATTCGCTTAATNCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACNCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCANGCTCTAACTATTACCGGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGTCTCTTNTCATCTCACTACCA
+
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
@r525
TNCNGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGNGTCGG
+
#!$)&("%+%!*!$!+&()%(&!#(*($&'+!'")'+!$$$*)'*'#*$)*'%*')&&
@r526
TTTGCAGGTTCAGTAAGTCACCCGGCATCAGGTGCGNTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATAGATCGCCTTCACAATGGCGCTCTGCAGCTGCCTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTNTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCNTTTCNGCGGCATCCAGCCNGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTNGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTGANCGTTAAAGGCGTGCATGGCCA
+
6+C5;CA,"G9@#<B-@#%=)5@*6><@/0>F%7*74@<A'&%=?%*@627&/*0.0A2#30B>D@A/FB0BEB+(=D519'E/%"$3F6*HG31?>B<(%/0@5)E@,802&C'=<<!<0?+B63H<:!:4FG#=AA+;A3E;B0;@>7&G>4$->=*<EF(?+D++%2.&B(+9*2?!+(==%>=70.)=)'B:H#$&;%$%6&1(")E8F4*$9/0<;1D=?D5G8.2*4"8E9/%0<-37&>)0*6@86#2GG-'EA9!1G7C$/!B3G?5/((=!.'!,$)3(9&?(6@<CF+??55*$%):9-6<:&EHA,5GC1D(2&%=$$H.:E)&$8*:/!F#G@(6.2854B(:1:F#91!/B!?0%;C)+@H;85>!B*AGB>@!88E9*9$7,/G)@4)=<<'<:*+5+0)-'FA>3CE>F8=;EC*)!G374C(,+-4;"FF-8;31(A"+/"++2D>&708G;&!7#@/!$$C('#)**83*$#-;D.'"B1>.A:6;2?@G)B=A/2."!A3F)AD,C3B4&'0C/'$.8)./#D3/+:?G8/(;!&@'2:@F?7FABE88>E36-7H.@%8":68?C1B';E#&@>'$6A3>HEF%
@r527
AAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATANTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACC
+
/80>6.*;,)2:,CE/A?1"$>::9&3E#@-=2D<H?G3)=A$#(?A7B7%E'65($1.$9@+=A*%?<C%!D+D*,-F(A+2/642/D)3B$.6%42<97/A6EE-*9(;BGEE6+=?32D(9..*%4/(?;?$3*9C@?E5>0DE%/"$GA$+.#F@==-0-0F4874-;+F<C
@r528
TTGTTGTGAGTATNGCGATCCGATAGATGAACGAAGACNCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGNTCGAAGTGAGCGAAATTAACTCTCANGCACTGCGTGAAGCGGCAGGGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTNCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAANCGTATNGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGNTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCG
+
A7#4--&=84,:=B7*.<-48D%/0E=/1?>'8%(%=6+-#4)2(?/(0"2>E="C(G8CFD=,H=D?!&D,>;H?6D;$;54HGD<5,7$H3)<9"+'*G2G(;=.205?7C,###)<>B3:D0%2H7B.!;=:%0+F"67*1!22#A)A!.?'3'E<3C0$BC*/;6;C*4+C!28AH2@%?,0=?),4<88'D>D,%<?&H:*4/0EA#F949%D%B6=E1?AD@*#D08.#<,99;92E$+FC8D!?0/1?;</3&/+H-,2.E4%2@?FE4'=BE'5;9"==E):A=CB&0F0'G9+'B;F-?/:$;8@1F<4.#D<52:7%"24-5<BED15A,(?$$><6$&+;/0;'#H."82=?::&$G.!<60F;=:+:C?*:G@:A-)63'6!9F&6D??:.C?=C#:5%)/&F=-2>G';&BE-7-2H@":G:2D3:2@(4+$DD0B<30)>>8;80<@@C4%,6G,4?E:>.03!?(8B$F&?*&#,/.?'$)@!-6&6A97F$1/(D?"<>A0F-%2E1(0'<'G@,"-4%/:FG>G&1.B81F*+,D7%-AH5
@r529
CGAGNNGNNTNNNCNNNTNNNTNGNNATNNTNCGGNNTNTNNTCANGNGNATTNNTNATNNCGNCTNNNNAAANGNANGTNCNACNCNGTNANTNNTCGNNAANACNNNTNAGGTNCAANANNNNNTTNNNTTNACTNGNNNAAACACNNNNATNNGCNACCCCANNNTNNNNCGCCAATNCGTGNNCANCCGNNGGNTNACNTTTTANNANCCTGNNAGGNCCCNNTNNGCGNAANNNNCAGNNNCANNNNANNCGNNAGTNNCAGTCNAANGNNATGGNGNGCGANNCAANNCACNTNNCNNNGNCNAGCNNAAGNNNNCAGGTGACNACCANTTNANCGTANGGGAGNA
+
"$#"#$##!##!$#$$"!$!"$!!"#$#$"#"!$"!!$#$!!$#"!$"$!$#$##"##$!!$##"!$#!"!!#"!!$##"#"!#"!#!"!"$!!!"!#!"!$"!""""!"""#$#!#"$!##"#"##""#$#"$!"$$$"!#$$$###!!!!#$!$#!!"$$###!!"$##!!"$#""$#$$$#$$"$#!$"###!$$$$$!#$#"#$#$#!$!!$"#$!$$$$"""$!#!!!""##""$##$!"!!$#"""#""#!!!#"##!#$"!!"$$$$##"#"#""!$#"$"!$##!$$$"$#"!$!""$""!$#""#"#$$#""!##$"#$!$"#$""$"!$$"$##!!#$$""$
@r530
CTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGNCAAAAATCNCCTTGCGCTAATGCTCTGTTACAGGTCAC
+
@-+$*B)G;%,&AB"6CGE.:1'C'5<,F:@'&%>4)#,AG*D-1<&B6A?&',:5,EB"3)'?%"-('>!?H?:824)376,(E*."/6#123
@r531
TCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGNTGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCNAAGCTACCTGTATTTGGCGATATANTAAAGGTCTTANGGGCAACAGATATTGAAGGGGAGCT
+
5D6?%@@9:8C$G;9"+B;G>.?9;)0C0916?4):*C,AGE$8H'E<3>,#%?&G#A6'4?8,G))84/8-F067?#9"A3+(4!8@"?,4H271*!)'%C?G;:"&)*-F67E/<.8BA.B6#G"E#0-H09D9.G3B;,HFG+)HH$;HD07G(FEH'/%:.6B4(-C:@8!7)2>@!"(')&6>:GB,(A@;@/"+A(68
@r532
ATCACCACGATGGAACAGGTTAACGCAGGAATGCGCNTAGCCCGTCGGAAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGAATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTA
+
3>//H9%A-9AG=3-5(/!"&41"(*@2;:<#'<>:.#=7E5+?<86*="1<;957#:+:<'#(.0'@#G0.,*9&D3@<,?('76D;0B%C8:G9$1;>"E=<"=&C049@4*6A:.::!<A*)9EC3!D>>*@/.26570$;+4!39>0*"7&G)6H43H>,7"5%=2)-#5F5%>)>@89,&.'H"G<D303,:@)>7D&)#<+2#A.FCB@D3+H&9"5?D"70G2'GCE961>)9(#3(C=05
@r533
GAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCANTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAANTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCAT
+
.C6*=7&C%H?E:"GG"?7%1C.>'BA7790778&&53)1,58+@536,C(#E>#6+."E%GF-G5E>A/!C$&D;<',3%9@?.=/7$=,30!6$/-"F;.6H>0?;AB:!G<)+,%:*:(1!H<A?;)+;F&'F7D#E-/->#(!#5(E!)</D)*#7#H;9E87G):<#88+CD%G7<6,<E66:!#'5<:(9B--26,>@-1,C(,GD-"0H1"28A1D21%;)@@707*&>9F7)9CEB$/E5B7A-6<%-F/->*>4;'8(@83/):.4":)1EB.
@r534
CCGNTGNTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAANTCTGGCCTCANCCAGACTCAAATCAACGACCAGATCGNCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGG
+
*)&"$(!!+#'&$$&")!"%(#$(*)'""%'*(#('*$+'%&*""!#")(*"$'(%))#&'&+#'&&+%+!!&!&!("+!($##!)'$&*')!()+()'')(''($!"!'#+##*#"+$*'&%)%*&**+"')(&$%%"+!&")%$**$+())"&%&(%*())%!%+)*($'#")*"#"'$#$&+!())%!#((*&#*%"#'#"""#&"("$$$#!#)#&+!''%*)*$*
@r535
CCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGNCCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGAC
+
F2/H'D"E&::3---H'8;%95FH"?F%'G=8*6#9-&+H#CG(3=7@2/>/)*,$<?2>4.23=!4-#->74>&</>9%0-48"'(/F?/$!@G"'8<(E*;;6/$,8-#)%?@GB
@r536
CGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAACCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTNTATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACC
+
>G5*0'9E0+,(=H8#,9$3)(),#(>2-@=G-?/7B.)(HE)922<ABB,71$,+H.17'=B/>"?H@1/$$=)@/4C2"3)@(,HG46=#1H.7?>="9>AG/G"19F.5H%24*<>3(#F.%9%=@?C+9@,=7="B(13:4@H("D-/GBB=1-*!#'-31?5D))3'C8'E=6<D"1"3*$/E3.;-FA(:4F(8'/)D+DBG?<324AF6B&;5D0."@@(3,(G6*:72A8$7/"G5")2+5$+1%D>(>'*//#1@7FB1;3B@3A5@;9F.+4D#)4>&&7@-+'!6!C,76&1=#7C71A'>HD'$@A?%D%,)0"'?.
@r537
GCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGNATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGNCGGTATGGAANGGGCAGACGCTGACGTTCGTGCAGGACCGACNGTCGGATAAGACGTGGACCTATAACCGCAGGAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAGGGACCGCCATAATGCNGTTGAGGTGAANTGGATTGNCCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGNCATTGCCNGTTAGGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCANACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATNTGCGATGATGACTATGCCGGTATCAGCACCGGTGGCCGTGTGCTGGCGGTGAACAGCCAGNCCC
+
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
@r538
ACCGCCGTTTTGNTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCCGCGACGGTTAACGGCAGGCGGTACGCCCCGTCNAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAAC
+
)6<.E#H'"!;?:'&'"/D?3;#<?-@65)%:?;B;!>C(849G66!&3!,$)<71,D&=,3GF&1%.!C?9<='>;/95(A:90-81=124:/B/F>75+5=)E2G:)EB+$")C>"&8)1(H-/>E"'*%%=?$-<%956H*G=50&:
@r539
AATAACAGGCCTGCTGGTAATCGCAGGCCTTTNTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACTTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCACGTTGAATGGCATGGT
+
1E&%8#5#5#&:C5$@!&#<6+#D;B+(!71<$)1:154H7/)3"#%+B=%B2,B'.=/04">;346-"F.*7.,<410$:/HGF'=B$>&8,.0(G&0$3+>4;@#G?/5"0<!14%*?HD:,F,B/"2+:B/2(#2B&%:2#A;+,'!5'@=?4D9FA6#5&=:;=35#@64%8:BC!7*H"=%&,5?2,:'@6!9+-;.->>##?'B.C-1#G398".&9':/6?G;"9===(>5$#58(
@r540
NAGGCGTTAATGCCTCCGCGCTGTGCGTCCGCATCCTGAATGAAGCCATAGGTGCGC
+
#6B+;3(@F4-;+D2&&;H.,13#.5/@"HG#=&?33/F.CE24ED<EAB8E:3/?%
@r541
TCNTCGATATGCTGGCGNGGTCGGAGGGANCTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGANGCCTACCGCAAGCAGCTTGGCNTGAAACACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCANTCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTCATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCC
+
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
@r542
CATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTANAAGTCCGGCACGTTCCGTTATGAGGATNTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCNATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCNAAGAG
+
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
@r543
GCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCNGGTCATACGTGGAGTTGTCACGCTTGCTCCACTCCGTGCCGCCTGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCNTGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATGTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATTTTCNTCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGGCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACNTACAGCGNCATGTTTACNAGTCCCGGAATTTGTGAGAGATAGACTTTNTCCGTGGTGAAGGTATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCANCAGTNGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGNGATGAAGGGTAAAGTTAAACGATGCTGATTG
+
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
@r544
GAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACNGAATTTTGCTGGGTGGGNTAACGATAACCGCCTNATGCGTGAACGNGACGGACGTAACCACCGCGACATGTNTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGCCGTGACAGCCAGCAAACCAAAACAGGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAACAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGGCGCAGGTACAGCAGGTCGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGNGAGCCTGGCTAACCGTGACCAGAACGAAGTGTACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATANCCACGATGGAACAGGTTAAAGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACC
+
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
@r545
CACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAAC
+
*C$/%C1./"472*$'1H.37,/'E4)F@@A=E"/)7,&28))),*!6"!>A&%G9!1>*E9-'!@&%H7<6/<>*?/;.;%+E;!<3;3:C7'5486G$6(D*,2753-';;1GF=85073B57%@0?F*?F?9$.6*(&B833-)1HB6@E$$;-?*)?+=$)!B"7.>+CGGD6H,&&<.C:A544H9E2-3,(?(D,&)#(?,C?C>7,(0<87%<.&-.&.4!:;>.%%80"=6/D*1;A(;'1!'5C888#9=A-C$H-"3<<13A%@1)GH&
@r546
GNCTNCGCAGTNCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGTCGAAAGACATTNACGCCTTTCCTGATNAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCANCATCAATGAAAACCAGCAGTTTGATGGCATGNACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCNGCGTTACAGAANGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGACTTGCTGNTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCNGAACGTCAGCCGGNACGCGACATCACTNCGGTTAACGATGAAACCNTGCCGGAGATTAACACTCTGCTGATCGCCCTGGATAAAAGATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATANTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAG
+
$""!!("&(*#!&))$(+&($)$(")*%'$*#!'*"*')&!%')%#'+%!""+)#*$&))'(+*)'+)**(%('$$+$$%(#+!*$!)#"('+)$!'%&%!!&&$((+")"&*)%+$(*%"(%)(%+#$!%"&+&$$%#$'#)$("%!*&$%*#$##"&""(!'%)&'!(')$(#'(!%""%+'*')#+!%'#+*%&$*"!+!&(+!"*!#&+'(&#*'&!+&'''%#$$*%"**%'#!(""&"+$)!%%(+*&#+$"#!(%$$#!'+*""(#*#*)'!%*(%#)%%%'(&'"((#***#!*$$("()&#!(#($'$)&))!#&')&(%(&')$$'+(&&('%"(#"++('#*'#$'$!!)$!!*&$!$+!(!)%$'#!#+$$'(&#!&$#+%))'($("+&$#"*%!""("*&$"$(#'%&#(!!(***)$""%!!!$)!*")*+#$'(#$)((!"*+!!($(*"%!+%'&&!*$'!)$($)!#(&$&%"%)++$!+#&+$&$'$&%+#&!$#+*##&+"))"&"!"$&)+&+%$$%#"*))&"!(+$+%!++(('&*($')!!!&$!'(#!'+&!(("('*"&&'"&%+$"&#'#'*"$%!#*!#++*"'%#+#*+!**+#"(()(*'&'!+)(#()%*$(+""%!%+$*$"#
@r547
CCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATC
+
8?B4;$)-&6>7"&B-9BA7:D;8HD;,(+&&60AF%,,>F?21+A%H9@-!-E?+-/F*.C?%C?8'H5,&05>(FE3.C<@:5F/*$9F<9
@r548
NCTCGGAAATNCGCCTGCTGGTTCAGATACAACGTAACGNTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTNATATCCGGATGCGCAGGANGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGNTCGTCATACACTGAAATCCTCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGANCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATNATCTGCGCGGGCGNATTCTGCAGGTGC
+
"!''$+%($!"!+)("!&**$*'*$&'%$(&'+'!+%+'((&(+$'#""+%*&+$$'+"&#'$"(!$+'!&+#%&)$'#++$&$$!!!#&+'*!##)%%"*!&!&%%&#&)+&%)"%+*$+(%&'%)*%#+*(("("!+#"$')*&!(!+(%("(*)!%))#%'&"(*(#""%(*%%("+("#'")&(*!$"%)*!!%*'#$"#(+'!$("$#((%$&#*"$*%$&"+&&(%%+##*%!)%$&(")(&#*)('!"#())!"!'+*+(#)"")&))'!'*%)')!%'&"%)$#"!$(&$$&"+(("%()+!('+(+)"%+%%#!#(*+&%#$(*'++!&##$'
@r549
GCTCGAGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACTGATTTGGGGACNAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACNAAATCGACGANTAACACGGGGGCTCATGCTCACAGTCTGAGCNGTTCAACAGGGGNCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGAGGAACACTTCTGGATGGAGTCAGTATGGAACAGCAACCA
+
$1+;)B@AH(E9B"B.<=(@6'?!(!$46-5H>7;0%(:'%CC>"+#((>!D-03;8#;2,*9C0CD<2/;8DHB"1F!+?A0E,BH+#7#%;5-?>-*+;96&9C=E</H5C(48/;70+/1.!$3.;:=6E;0*5&G9$C5)*#?"8?/?)?<>),?$D0"G:9$H="A@#F($6E674;"2?='#!+6*(+32#.2/?<@(%.H&"C9F+;'4>686.504%E>9@,<9$+F)B/F(H%->/+8E+8%")()9:"?/(=&9?,-"@@HFH:%')2CGE-EF9"E"HA($=''/8:0483-!#@%@!649!.E'&+8448D%(>+:4D
@r550
NNAGCCGGATNCCNTNCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAANGNGGTGTCCTATAAGGTGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGNCAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTT
+
##&*)!#%&(!*'!"!#'+)&$+&$(&$()#%#"*(+++)&)!#$#*$$(+%+(#++$*'&%)+))!")*$&$'(*%%&'(#*'!&$*"%#(%+#''#+')+%*+&)"+'('$%#'&!')#!*++)'")$&!&!)&*%)&**#+)%+)+'"'"&&'!$&'!%!+&!%+(%!*%$%)#"(#$&+'$%($*+&&)'+)"&%'$)+%%$"+$$+"(&)+))")&+%$)+)*+(+(+$$!'"#"$#()&*$#((%+'(+*#"%!*))#*#'%*$*&((&("$#!'&((+*+!&+))%(#')#+%+''#$!
@r551
NTNCCGNACTGCATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCG
+
%)!&()!$$(&$*(!+&"$&)!)&'&!)*'###()*%%*"#$*+%"*"!*$%#*$&)'"#)($"(''+"*(*"'&#&#)("(#+'&(&%))*"*""*'''&$+*(!)#&$(#%+%+($!#"$*'#"$*$*+)*##(&#%#*&"&!%$%#")'(#%
@r552
NAACAGCAAGAGTGCGNAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGCAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTN
+
&'(+'')%)*(*%#($#)%+#'$%*&*$+((!%"%#$"#&&(**&!("*%"'!)'(*!"'#+#+%$$!(%&#"!&'&!)*#)("*!*####+**)(')'&&*%*!*!
@r553
NTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATG
+
,G3"A!A668-*7==E&1#>.@D:"'1"'%@2;7#@7#*D@
@r554
AAGGACGCACTGACCACCATGAAGGTGACGNTCTTAACAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTAACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGTAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCNGTAAATATCCTCAATAGGGAATAATATATGCTTTCCANTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATA
+
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
@r555
CACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCGAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGT
+
,'1FD'$&!85$B:C(C1#)!"-9?/;60<**C3B,2%*@F-<HECH8-G6+&'&!;H;6$H,'4C:9.#0,&.57$<,+5D!;+()%F+)F;>B",A*?27B1#*9F8;914&=-,4F-*@D?3@:F@#G7%'?-5/A7CB95)59)=>&)=:)H96563B4D%$+-/!E*+'3;4&8E12#?1(&%0.0B>"=38./"D'HC+4A$$%#52:4:4:'389#>B!7&6A4"#A;GG4H?7$DC?2:H
@r556
AGAGCTTGTTNAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGNGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGTCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGNGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGNCCGCAGAAGTCAC
+
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
@r557
GGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCNGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCCTAAAGTTCTCGGCATCACCATCCGTCGNCAACCAGATAAGGGTGTTGCGCTGCTTATGCNCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGG
+
&<"(500>1&H)B.$3E<B78D60;0#><.#&@CB<7C;F)-@654@!%C,0),-2E'AC-".E+(@7**H2-0"=2;>?5G6&C&&'5(6/<$*>'BD(HCE8.*..C"98A?*3>8??4/#1B;'-+&')/)5&"CD/#E9;@9=E,D8=$<(AA8*>#;E04@0:BHG!D@!A0.A5+"F+518220"4"&/&>@:9&)C@)22,CE$.HB-+G+*8/:@7!"6#;3%?!-45.9D*)/902<'$G$<"&)E!4@/2024H8(D+-&0:=/2067!@,!>E>".=H##1"7<6+>66'-.EG&*E5CA0G/D'C;B<-*@&BH&H%5F$#A;!@EC2(691E%2$A-*-!%;F&//%+05$5!="C@$>1$?><B(&,A<,0FC$"6
@r558
CGNCANNCCGGTGACCANACNTAACAGGTTAGAAANCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCT
+
)%%$'"#)%*&*)(*($#&'!#(+"%"+(#%%("&+%'**!'""&+'%!!"%)#"%"''&&+')%((&(+($##+!(($#))'!'+*'+!(**))%$+&#+*+*')&
@r559
GAGCGCTGCGGCCAGTTNATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCNGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCNGAGCTGCACTATCCCCTTTCTCGTTGT
+
6A8BEC'7,@7/=D4E=+*>6("D0$"1-,;7+1!;1=?2,!*.2F&8A6'0317B035@4C:>H/6'A;BF6&9:@(7+3/'/A,1'3>4DH8$>.2C0(G=&3!/*?C-4??H.-?*#-+6(%.@*B9)/7@<1>1>G@.200D7;=G%AD07=H:<6G:06(&64:!;/5?ED++%+%9B,4A6G.4C;:?-#6(8/C8)(<>C7B*,!FA!B41%9<)*+6=86F&%/438B=""!9(07#<2(1A<1*$<.:4:>D0CG'//1F2EC#?//>:2A;
@r560
NCGTTTTTGTTTCGCTTACGAGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTTGGGGATCACCCGGTACAGCCCATGTTTTTTCCAGCGTTCAT
+
#+$$)$$(')"'%!(#!")&)(*#&!('"(*#&$*&"#!!$%$"##"+"#"'$'%!&'#%**)*))"*'$%+*!!$'($(&#$"!*'+)#%"""''%)#&&)('
@r561
ACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGNAGC
+
?=49"CE9,=,:>A(2&($@G+7!:)&!4H(.1G0HA?/H3!B&2%8'209DA";7@
@r562
TNGNTTNTTATNAGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGNTGGGATACTGGCGGGATTGACCCGACCATTGNGTNTGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGA
+
&##"#%*$'(&%")+")%('+*"!!'!()%*#+$$)'#&!)*(*$("'(#'*%*#!)$"+)*"'#$&&%'$$"!##&+)#$()$&((+')&"''"!''"'%#!!'+&*)'&&)*"$()))$#*+(!)'*+(&(&%+'&"(#)'!$+&#+$$)((++)*%!&(($%%%'+')&()#%)&#'!'"%&(##'+')'%+)"+#'*#))'+))%&$%(&"(&+!%"&&"(+"'#&"+(+$+&!(##$&$%%&!&&)#''*&#+%#'%!&$$*#+$%+&+'#""""%*%'%!"'"$!&'%$+&&*$&)%#(!+)+*'!(*&))$'%(&#(&'#!'"
@r563
GTGCGANTTAATACCATCCTGTTCCTGAGACNATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGAT
+
@.&-0@!=E$=)(6015C!5+7H?D>(FAF!$$(A;E!G+(B''5%>E,!2FC0A&(G/G=@&D>--"1""*2&@<:#D$D3)/&)-,&HG1=$,/E'H8@$",D":-#?>299-',))22244+CDGF+D)3
@r564
ACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACG
+
8(F304*+.@G!F>.D4=3+.7*%5*<>#AH%<F/B#*!-8HH0C<-"D,F)+>G)'?:!HB
@r565
GTNNNCNGACTNANCGCNGCTNCCGTGTTANGAGANTCACNTGNATNNCTGANNN
+
#!!#!"###$#$"$"$""#$!!$!!""""""$$$$!"!##!"#$$#$##"$!!!#
@r566
CATGNGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCACGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCG
+
.A<&D84-6=*6F:7%F%$()(01H%:=*-$$:D;A(#4!40=!881%%1.>?,G"%<<0A-37F%*GG'A0(CF=)D96$8$2859#D)<,07)#H;(,F977"33#90(A')E.=*D2,<0<BE7G#9>A5*$>G);G%%H3/((H1,6:BA=-@@:>HG4;H&:59F0,D'=4)/13(+5,&7C6@1H/3"F3&;:E/@@'9558+914&,*FH9:!.,B>'/?)E;,"9.@E2$/&'B6"$G)5332
@r567
CAGAAAACAATGAATATTTTTTCTCTGANAATAATAGACTTATCGAGTCNAGAATCCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATNGGACTC
+
$->F;#%,23=:.7<#$G5BH)">'F(,<AH@2?#EC;$0>A03?<-35F09+",-'"&<,.'H*3/@(%,HA"!;7-E0%118-@(GEAD0-7AF"+;%-4D*;E*7*82!=%3C?-%F*;9:BH;E<-D7@("/G%*/%@+("%:';<,'(%$%-5G*H)==G@&.**952
@r568
CGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCANGCATT
+
G92@428?-%%,11>DC5=1/@:+&7!..=>:1!8F76+3(,5:?6#34560?B;CC>G47@87'*B?)D#+5DB?G92034(+?9'.D+&)C,;3C)?49C!=@<"8)-***)@"=+0?HH/.AB"%%/5E;0!<-!9H6F?'?$F1$6+:@<,'0=2?0!%/H!3=-$H20:/"A#3$5)0/$48&)H&12B8,54+3@H'D5-B*#'4CDE?F5*>3!&0E@1*
@r569
NTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCNCGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACAGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAAT
+
!E5#F+!F&3F)>>>91?'ABB/H",41;!9DA@?.</B6)B%"%%)04FGAHBHC+G<B6%&%&!.1,9;(?1,6;%/)%53(?0@D'802".3A;:(HB'9=?E<G?D)<G":<H7F6.-5?$AG!0B():'22'>#:@H
@r570
GTAGGCGNNNAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCNTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGNGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGNATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCCTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACNTGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCC
+
%$$#')'!%!)+!#'*#&('$%'))(&)%"''')'*+%&*%#$'')!*$+"%'&'')(+$%("(%"&'&#(%%'"##()&("'**(++(+$&""(!$!()'$"(#+%#%+'!(*"")#&*+!!*)"*#+$(%*+"!##)*#(!'$$#)'#%#**"!*%##%&'*!+#%%"!)#&$%%''!$"&')'!%)(&!$*'"'!()'+*#&'!%)$%'%$("+"&)(!&"+*(+$)(+&#&'*'))!##)!'#+!"**")(#&((+&*(+(''*&'&+(%(*%)***$&+#($$&$%!%&("!)"(+!!'%'!+()%+#&&#+&&!'+(!""*&%'+&!))"**'+%!'&*)"%&&"''!'&$!*#)&#!+%#''*
@r571
GTTNNCNCNANAGGNANNNANNGCNCCTNTNNTNNNNCAANNNNNNGGCGTNCNTGNNNNNNGNCTNNNNNGGCANANANTNNGNANCGNCANNGCAGNNANNANNNNCTCNAAAANCNGTTATNTANNNAGTNGNNNTNGNNCCCNNNNAANGTCNGNANNGANNNNTNGANANTCANNNNNNATGNATNNCNTCNNACTNNNACANCANATNNNANNNACNNANTNNNNNANTNCTCCATTNTNNCNANNANTCAGGNGNCCGCTTNGANTNANTACTNNNAANNAANNATNNGTCNCTNTNCCCACATTCNTTCNGNAAGNGTNNGNTNNTNCNNTTNTGTCNNAGCCGCNANANNNTGCNANCTCCTNNNCTATCNNNTANATNGNNNNNTNTNGCAGNGNCNCTNNNANATACNCCNGTNNNGATGNANTNCGTACNGTNNANNNANCTNTGNCNTCNNNNNTTTNNNNNNNNCTATTNTTNNNNNNNGTCNTNTNCGNAGNNACNATANNATNGCCANNCNNTNNTGNANCNNNNNNGANNNTGNAANCCGNTNCNCCTNNCAACNGNNCCTNTNCCNNNNCNTCAGCATNNTTTNACCNANNGACCNNAANNNNAACGNNAAACNNNGGCAANNCGNCTNCNNNATTNANAN
+
"##$$"$""#!$$!"##!!$""!$#"#""$"$$!$$!#$#"!"!$##!!$$$$""!"#!$""$##""$""!!"#"$"!!""!!$#$#$$$$"!!#$!$"!!""####$!!$""#!#!!#!!!#$#"$$""""#"$##$#!##!$#$#!"!#$!"##!#$$"$$""!#"!#!##"#!####"!!"#"#""##$"!!"$#$#$$#"###!#"!!$"!$$"!$$!!"#!$#""!"#$"!!#!#$!$"$$!"$"$"$!##"!$"###!$#!$!$!!!!$#"""$!#"!#"$!$##$$"!"#!##"$$!##!#"!$"#!$$!!$"#!!!#$"##"$###"$!!$#$$!#"!!$!$$!"!!!$!""##$!#""$$!#$#"$#!$"$!""$$#$""#"!!"#"$"!$$$##!""$"!!#""#$!""$!!$$"#""$##"$#"#!#""#!##!!#!"$$#"!!"!"$$$#"##"!$!"##!##!!""$"!$$$"!!#!#$"$!#!$#"#$$$!"$"$""$#""!$$$""###"!!$$!#$###!##!!!!""##!"$!!$$!!!""!""!!#!!"$$$$!$#"!$!#$$!###!#"""$#$"$##"$#$"!""!!#!$$$#!!"#"!$"$!$#""$!!#$#$$$!$!#"!""#"###!!####"$"!
@r572
GGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCA
+
&B=H*2.>C574>@B2).%GA$'+E:=D;:@0*678ACC3('A>+!-%$.D3?9<>%466H=?!&)?$H935?=$&
@r573
GTCCTTANCACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTATGTTAAAAGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGNTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGANATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTAC
+
8-2A($81430+G+@E%(!H88G)D-+GA0?A>'D-%9?/>4,'GD:"AH;E/<?7,E:AA-E@6%!%H23E9C/@9,2<50"H>H2D#(%)+$%F?%"%-0#(9.2;A5>=-.:DF.0"G?-4E62%@4FCF"/>D6=>,.AB/F1=@839H56D@?977.0'>1;5:'0*E0(%262!>8FB,>7390?F@0*7CFC5<<6&9&C-)G,7120!0:'@%4"(DFG5>3()*7.E$6;#5G99&,<&>GC,9E?E%67A347;:9;G)3$=+43C-*C+@":3"*0*C2+.";G$:.C/(F2%%+<D<##!39C?8$=):GD'DG001'&+0$6$',$/)G2<G/')>+%C3?F*.<7)&;?9""4A"7DD,B&?#
@r574
GTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATNCGNTCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTNAGTATCAGTCAAANTAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCNGTCA
+
)*2.&F<H3?%G?A88:,;%50/C&:.>-&(%F*5'!7&:@1E4.)#HA0<88.!.$.644D"B*:"/;A<=?-E')=/)'4G'/A3A!GF#6760A;<)#EH"G:36CGH94+G2%3,F:>C=GC>5893"!9(EE=!G..?;!96;0H7,&&1%<+-@8:)61*);2,6G,($(=/@)G0,A',D7*?=H68(A//9@?!B&#-/E94'"+,.;"=9=*C<#/69'3!5"9?%)*1.**(GG=CG5!/!B7%A;(?-'(.&<!372CG30@8B?D;"):*(;8F6..',<"C1$'91H1!$F71D+7)9%,"H8'HF%B'/3(+%3H'6$6-@5%EB+)
@r575
GTGCTGCCGCCAGNATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGAGAGCCTCCTCACAGTTGAGGATCCCC
+
7;F46H?G(2(#))+?ED';9D,<"!=&3!D$;>*C+'<)4H-2:>(-G2!0):)C)+G6C$A<&33,<*H279+#DAD;:20/-G/4<1DF*>5<#9,6E':D,.&#;%
@r576
GGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATNCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCA
+
C4#=$)$%8#/6'BD()BH@*52A+73!*-D&D:48*/=7A1%D.#D,/C).D40./;2?>@8!,(,B/C@4'H3CD,B>C4"D*7CG95E,DF3(
@r577
CAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATNTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGCAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGNACGCCT
+
0-2)E==E*@.$,B81!7E;5%*2&).9A63G*.D$"C(H594,87>2%0@B;6E*+@39,#9%#5.<C3+(144(G:A4/B'813("3(CD&;!&;5671-#'3=2DE7:'1:..,/;4H/7C5%H+4C@@/*$&&.7-@1"&B<,48=B7'.%02.:/=/;B14*F(>FGH.AA%84.BG871+96E,!BC
@r578
ACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGNGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTANTACGCGGCAATTTCACCAATCCAGCCGGTNAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGC
+
7E/<1/8,9D%F:$7C347H&-?*9*#E*.)12#'?8C!*-?:"H(-.7$-#8C?*G6+*-+16*0'7D$0G=*/BA!*GBH@:(*:E%,9H:3'+)E1DB5'E9$E6</<B&)A.7("2DG./C<=F6!A7;";F&+,12B$;E?9!2"-%9A#@E.>,$2',!!E9!4+4H)735*?7;;1455%'>?C8/GG
@r579
CTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACTTGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATG
+
<!+G;G)GB,D4#!CD*!65@0?69!9+7B9!.4H8(@:%8/-6>9,A=%/@,-45?+$*H@'0D&26#A-?;1A*$;G,?C0D9*H**&+8B'#)%()AG,5,-C1;=35!!;5@&F@/E%)FC("7@<65!>(4A29>92/A,(,93?:?(&&-=%3>8-F7?9FD"A,5"AH3:='=0D&-E1*GE)5!89G40/81EHH"F05++AH>-$F0-.7B5$,*6G:3.A$2G2&'A)*!<,3/6%CC0'336.G*#G(,,%"24E,?F06;;6'#>E=&FB#(H
@r580
ATACATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGTAAACGCCCACCATTCCCACCCTTNTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTNTCACGGCGGTGGCAGCGGATTTGGNGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAANGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGA
+
"#$'+($(+#('+"")(*!#'"*"&!(%''!'#++''#!+!!)+$!#'++)""'!*!"#&*$$!)*)'&'$)!&(#*('"#%"#)*"!#&!++$)")+*)#*(!$+%)())$&(%(#+#"("#&($)&*(&!"&$"#)$"!(#!'"(+'")"!&%*!#&#&**"((%"'%+!&%$$$($%%%%'%*))")&"#!+''#'!++&"#+$+$&%$&(*)&#)#**&*(($
@r581
CAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTT
+
83#4C>>:F-(E!C:?F$;*@3H*+4("45@6B3-%/""(*D69:!2A69'+29F29":F'DF0()!>"ADC!/&:=;DG<<7B.>?:D>+3B=2A/B*,&":.'%2"@>C6"?!:C2"&5@)+)44@3#A1=1)%0D8>H9%H-3.9@0=<$(2<(G
@r582
CCGAAGGTGGTGAAGGGCGTGAGTTTNCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTNAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCAGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATNGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCNTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAANCGAATNCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAANGACGGCAAACATTATGTNGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCNGAAGCGCCTGACGGCCCCCACNATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCNGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGNGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTNCGANAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCT
+
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
@r583
ATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGCCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGNACTCAGGCGNCCTTGATAGTCATATCATCTGAATCAAAAATTCCTGAT
+
7?(6-16G--34=5@'AE3A21A&&"(?-)!FG*<E6;77?A'54H<%66<H3-:91/8@-C)6*?1#$8.%4>;F5B,,#"G$0B66>%-.9$+@A98:</-0"0(!F@8*'C?F8AF2+&-,H@F0=B%F=','=1%<3<DF!$C,33++DHAC)<98:-B;-':(;E/0F=@":)=9)+/,$'-,F>)*7G0',D)=40($A:76A;#6;':(31=<79%?,@3B<!@:E*=C5*31*"G>#>)@7C%",:'*(.C%%,G6GG"@--6!%%D:85;D6);<";-0">@2<%H#HH*53%4%
@r584
AATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCNGTCGGA
+
4$?6'847<4(B&>#H,56<>72B1E-=8G'D@<8H6!0(/+E7>?<66A$-"4<8(".*&#@622"A#;H$)*'1B7B;1%4
@r585
TCATTTNNTNCCAAANNNCCTNATGAATNCATATNGGNATTTNTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATTAGCAGAGCATGTTGCGCCAGCATGATTAANACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATNAATCTGGNGAAGTTTTTCCTCTGTCATTACGTCATGNTCGNTTTCAATTTCTATTGATGCTTTCCAGNCGTAATCAATGATGTAT
+
&(&*#&&$"&&$("%(!&#(*")'%#%)$#*"&!$%*$"#$*(+#&%+'+)++!!%"#")()*!')%!$%+&!)(#%(#(&$"*'"!'"!%#&(*#++*+("("$+)'+)#$#+&##$(+*(((+)'&'!!&%#((!*)'!!%"!!('##!*!"&((+!('%%+'+)(&!!)"#+!)%(#+""%)*(##&("!"")!)**(*#(*#$'*&()#'#('!%%%+)#("'%+)"'+(*"'&&"!'"(("'"&$"++$*#)*"'*($+)#&'#$&'*#'+#")&##*!)+&(&*)&"%&%%((+*&*#'((!$($"+'($"(*
@r586
CCCTGTCTCCCCATNTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTGCCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGNCTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATTCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTNAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCNGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTG
+
?6#-0+3:-F-6D(0'5=E-A>".@2F(A=D8"DFH#(5G##?H=/<F%/45AB0'H!H<2#,=.**'<G&F;F%64(;B=($1.-H:"97,H?G!>E*<085*5>9/&@@G$H>$8D+5$,>)%>.#@)8%.C<4$G??"#?F'5:&8-B?9<);:E6(8/7!*H63)/"+>/7*@4)4*@15-B7;=F*G3(*E:47D=*HB:3!;*%>2-3H,B%*>2&G34+3D$8A.9?G1<4)G&@@";H+6+F2=4@>3C9&<.!>F89/AHC,-%,+F8,0B"<7-$6$/G'E8!#%%F?;83$HH:&(6!7DF=+GH'*2@)5/=4'E(F6:3/!?"C5&3'(A4/FF4?#H*?:;#2D$H5A39
@r587
GAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCTCTAATACGCTAAAAGATTACGAATTATTACNTGCCTTAGCTATAATCTATGGCAGANTGTATAACTGCTGTAACTCTCTTGGCATACAAATAAANAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATTCAAAACGATAAAGTGCGATCAGTAATCCAAAACCTTACAGAAGAGCAATC
+
+!)%')'&+!"*#%*)'")*+*(!"(&+($)(%%"&#)*)$!+%(&''("$&"*)'+$'+&&%$#$*)%*%"*('%(*("*#&"$&*%$&("&")*&")&(#&&%')*'!$%('!"##*)&+'&+%#&))%(*#%#*'('*'#($$"&!!#%+!!"'*)&%%(#"*($%+*%%"%"*$)+))'+)"!&++&'+'++!#++'+($+%#'$)(*+"'!&%**''(&%&)$")*#*&'$)(**&$
@r588
GTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGNAAAAACCGCCATCAGGCGGCTTGGTGTCCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGNTGTTCTCCGCTTCGATAACTCTGT
+
"557!H1-&'A$=H2"B;137&(G+;<0'+B52@"&(*E?=9,<H<?H&C'E</3/$B6,;1&*,.!?)?G-.<)@:F;@7+A/G%!4'-498'.$H>%$/<(6BD2:'79!#F1*1$9#3@B/7(/4%(B!'3B7B@C4E2<F!!/+BA0F%H(9E?+*B!(9A=D+F4"/,=&'&H(==8,&!0-.).H8?84G%!F:??)36.EF18>4083$+15E6C@6=6*14H4=C352:>7!F)9!G?>%@64D%1F?!-&<4
@r589
NCNATNNCNANCTATCNGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGNAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCNAAATATGGAAAACTACAATACGAGGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTANATGTTGGAGTTTAGTGTTATTGAAAGAGGAGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGNTTTTGTAGGTCAAAAAGAAGAAGTAAGCAGTTATTCATTAATAGATAAANAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTNATCTCAGCAAATTAAGCGATGNTAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGGCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACANCTCATTACTTAGAGGGNTAACTCTTTCAGAAATTCATGGACATTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTNGGATTTCCACTTTTNATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATANCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAAGAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGAGATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATNGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTATATAGAAAAAGACAACTCTGGCNTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATNTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGT
+
"*(!'&#!#(#'*'"*%*&+#++%&*++&&**")%%!$%!)$"((%((*(!'*#)$+#)!!(&")!%!#""("!(+*'#!"##++""(+%)!'&#)))$%+##(%)!#!+*&'%!&$$!"&!!+*&$&'"#())%#!)!*+$)"#++)#&%&*%+*''$#$*+")+$%&""'#$"%%("!'$$!))(("*#+)(!#+"(+#'!!+))""$"%#'$**$'$#!*(*#!")!#(*#&)$+(")&+'#)"#*+(*"&$+"!!*'!!*%+)+%(*&$+*&)&#"&+!&+""&$(%&$$+&"!&(!$'$'#"!&+")"$)(#'&#%&()%$%&!'""+'&')&'%**%%"(++!*$#$$%(#"$)&$%*&"*'&"&!*#"&!&$+!#&+$+(*'(%%)("$'*&*)&*#'$"'&&*$!(+!'#+(+$%%%""'&(%)$('*#**$'#$(++!#(##*"&%%("$"**)(%+&(!%"'#$(#%$&&!"%"!+''&$'"#)!)))")*+*#!!$)'!"%$%+!!%'$+&%*)!*%%$)#"&$'#&$(*('##)&!+$!&(#!)&&)'(%#*&!#&!+$+"*&'**)$+#'#%&+%!()(##$&(!#%("&(*'$*'*&#$&'++&)""'("'!($#!%#%##&"*!#"("!&'%&+%*!#(+&%!&$(!+!"'"!"!''&*$)$!!!(*"&!)!!#'")%'('('+'!*$)()(!#'*#(#'%(("&"#*&$&)%+**+)()$)+'!)$!%(*($($($$'*%#))'%%**%*'%&""+!+&!$&&(&#$&%"$+%+!&!"&$+#"))*!%$%))(%%()##"+'!(&%$!##)#!$("$)!&&#)$(+$%%(+*("+#)#'$'!"!!%'&)'%)$!)!$+(+$$&)!!'&&&*%"'"('''#((!&!#%+*+!"%&$"()%'$$"""#%(&#'!)&+)*#!*$("('++*%''%(')")&*)%*!%'**)&'$##&))'+#''&&##&(&#*'&%")%!&)#*#"!!+'("!&$(+'%#*+&")(*$!&%!+$++'#&)!&$(*""$+!$$##)!&*"""(#!+&#$)!$!++***)#$+*'#*)&*(%!$*"#)!"*)+*!*%!#%&+*#(++$%#'(*+'"*(&(&#&$+%!"#&%&'#+*++$)&*"*+)$(*""'#((+!&&()#%%&!#(+'!$(%(%$!#%')(('"*))$)'+)!&!)%$$"()*"#*&(%!()*)%)'*$'**$+!))&**%$"%$)&*%)$%+)*")%+(!*$&($$(%(&*""+#)$%(+!'#$&&##"*)*("*#%"!'#'"($##$+()"*&#"!!(#%''"$*')%)*"&+#(*%''$+#"&
@r590
CTACCTTTTTTATATCCCTTTTAAANTNTGGCTTAATGACTATATCCAAT
+
AB<&B3=&H<4:(+HEH<7/GEF/0+B#<C04<82085#5*&9#'.+&@&
@r591
TATGAGCCAGCGGGGATTGTTCACCGTGGTGANTTTGTCTTCACGAAGGAGGCAACCCGCCGGATTGGCGNGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGNACGTTTGAGCAGAATAACCATGTGGTGATTAACNNCAACGGCACGAACGGGCAGATAGGTCNGGCTGCTCTGAAGGCGGTGTATGACATNGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATGCGTGATGCTGGCCTGTTCTCCGGAGGTGGACGATGAAGCCCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGNC
+
$#'?G#DB*<A)$8)?*"/=8/'>"?F#'9/@',H!3:/H?("=9>,?@GG@+H%.>!!<F?7)96=0+1/F;#7#=;E,?G5"&=0'8>;0E"E?$2(7D9+%7!E-H/'B>B3'B,(1H*/D?217)"/D'.((&%*58$8?H(?C=GB&<>6&<;.*F(0+F15?!186<7:(,..!"6D2:!H7814AC=$:CD@&/G9)@/>8A6!)*+D58@/G?4H=F'"E1&0>#)H>;+):8A0<"-#BD./8#(4F;7!1D2,7@@5F'$58G)1#-15<G-D?9'=5#<EE>HE(522";15$>;6H"B8.G6HA$75#$%+'>A#!F?F)1?'6*$B4E;:<(D92*B'<1""B9A>A1==73;"@%-6EG0B;57+4*A-".E#(5:$<='2#5&(-!)5%'A>$C#6$0)%28;C"E!0-3$==-(&
@r592
NAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCGTTGATATATCGCCAANTACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCNCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGTGAATCCCAANGATTCGTCATC
+
$E-GC8G,$%61':G&.E&%&AD/,&-=()&AH+$G$%BH'?G5,7>@'>!4@,.A$B7@/=8",/',0C%,94?0?4)-!37AB58H61*>-BA4(<>1'&?:C%8#?""2"C>F3BGB$$<&$B#59"/&;46=?$DH?A.>$8"%6-,>50$5A6"9/G#9#@#(6C&8-1(D,-@H:&+93+9H;&-,)4#EC1B!"&#B!F(F?7+3"<>G)$6>-:@4,51D0HGG,1:BE>H2G,*)@D3*0/9+$"?E:01>:GB,-1$?-<D5)"'D927G?586>BA?A'ED*H@H*DF8>A/BG
@r593
GATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCA
+
&:!(?'-&'93.F$+!C+)-&'*!4F#;<A4*D=%C%!:;.?;)3CE2-9%&A=$;35-A<:$=FB6.$HF@3F8;4$,AEF'H01H/3'4-+$2:"BG/E<9915.>9&*'
@r594
GCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCCCCCCCAAATAAAAANGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGGTTCATCGCGGCACTCTGGCGACACT
+
83:9':<A71->1(.5=B%$"47&?B'6<(#..;/@G.9?=%7BG)=/B6>H!)H#A<%*1$33F64.;B<<C/D4E@H@.GB=4G!,GB"3E3D/:9D>@$:+7E?=*H948F9?&0D"=-F)G6?+!,.!'>,:"!.%F&'1.H7&5"9>+6E%?0F(D"$>:8*H&2;?),3'??<+:408G!+@3.!!*6G6='3/2*F$5$,3.7>A>8>!#CE&BH264*?H=%EB<>HG#AE019D0?&81G:)>F8:
@r595
CAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCCAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGCACAGGAGCGTANTGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGT
+
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
@r596
ATAATTGATTATTTNACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAAANNCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATNCAGCGTGTGGCGGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCCGTGCCGCTGNCCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGNAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTA
+
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
@r597
GTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGC
+
-$<=2E+.2&3*F'4/A%(<E5>$6:-:,,@E+4,*);7,A7*>6*:B#H,#C67+4#BE4-8G"&3CG>*%0HD*C8)7H#E>DC)=G)8$%.3,',6@)?7*.2%G65:26/45E=4-);/B-:?<+F2@+3>,--B83F=#E!B@DD:
@r598
CTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTNGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCNTCAATTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCTTGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCNTACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCA
+
??AG8<:F<=9*/>DE.=DGAA?/>E'@7(A1?G69*(</E(3*)$==)D*A:45.+F<H0?/5(@-82E'G!>7E=+7=?BA7'==B@:E":=%$-@FB-1@*@&"84++A1589*3,8%'=3?$(90>;&F.434?F#E@-2="F.7#H:(B*?49?H5"A6,$65"!+D/CH"-?+FCE$#.%1019.=6!8E=7"/63,,$:<,A8#,A'7BD1H'.'3>-@1F/!"G(&4');./:#@<'$/7<5;8#!42!+7')D>"34BE9B>.D;(!>3ACH::?+4'7D3'?$G8+@.A+:)%"$G/2<6.D%#(@42B(G!:&,-2'/<>F=/;F&!1<1"(239@,/!?5-#6&'60:65;2!7%3@2@!$
@r599
TAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCC
+
=;A)9*9A37E%5/.+,115;3".*F,-/EH:%!;,!%!1):53340(7;0?4>/.G+5"4+
@r600
TGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGTCAGCTTGGGATCAGCA
+
G>-80/:'C.F1-05+402035<1F63E!#G9:6F-239%)!::CEBE9G$+4@B**HD@99(.@CF(5)5)G?E?1!E)'(H@D-57-A?3!40($->%8%"#:AGHC'6E@#%>7%"'>1F>6<'<"F2'0(?C=<='#!<'<;-,:"A"%'*H&.B/A,!H97C:&"A4G)>,4E?@/(/,;!;8/,9E1<0?F8=F179(A/D>8AC42(<$=#1>;D-64##,2:'11?D#33#7@.:;831;&5*(+>@%49
@r601
ANAGANTNCNCTCTGNTTNCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAANAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGC
+
"&$$*#(")!'!%"'#%(!+#++#!)%"#$+*%'+*%*(&#$")%'"&#*')*%(!($$")"($!%)"!'!*"$'+$#")($'%)$'!&%)*$$*'&$!%*!*&$#%+'$*$'(!*+&(%$"%
@r602
AAGGNTNNNNTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCANATCNTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCNTGGTGCTGNTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTNACACTGGTGTGTTCAGCAANTCGTTAACGGCATCAGATG
+
"(*)!$#$"'+$#%$(!%(*&&*&)%%&#+*%"%'"')#"))$((&)&!+*&$+(!"!$'%#$)"#"%!&(*#%%%&!%%$!$*!+%$%''&"($!"*(+'!$%&&)#*&!("+)##(!$)))%+&&!+&#'"+%+$!#"&*(%&$&*"%%+*''*(++)#(&(!$$("%!)$!+)*&*"#)*(+%)(#)*&%"%*)'*$!*++)%"+)#)!($)**&&)*#%&'&%'%*'!&%(!'&#+"'&(%(*"+##()+)&%&!!#&*&!)""($%)++$+&&'%)!++*$)$##'"++**)+**!#()#&+(%"%)("(%$+*"")!#%($%+!+#+&"%**)')&(*"*&#%($#&#'%!'!(#)+)!%#)!)!'%$#%&'(*"&#+#$*)&#$+#
@r603
ATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGNACCGAAAATGNCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGA
+
B.&)6>)H<,A=/2B-D9D.6F@:;92!D1B(69G0(>.7=,<-,E*@@.0=57:E'&,-@A#HH,1),9B7@?#%.>B=(.GC%3D'.:*H,*>);;?B@H5='D;2109/(17%4H1%.0+CE@."=9>(:$H(++G/"A!A;E<G$=0*BB$&C)@:
@r604
AAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGAGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGAAGAGCN
+
CE76;6=&!!3!);?A'-F5H)D=!!*:,F$&G3D?5/#*5<E-2))%*2G/3>55)C.F;A.<DB;:.!3,,,9944@-9$-CF2,?$
@r605
AGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTANTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTAAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATNTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCTTGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCCATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGNGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACTCCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGATGGTTATC
+
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
@r606
GNNTCNGTTTTACGNAGAATGGCAAGCAGCACNTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCNCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGGCACATTACGCTCCTGTCCGG
+
&!")&'$+!&"+#("+'+)"#(#(*"+*!+*###!*#(!*%'$!%())(+!*!#*&()#!#*&"&#('*"$%!$)'$#$$%#"'&'!*#!(+'&#*(&"*!!&(&!!%")""!&))+$%*$+%)#*&&"%$'#%+**)!
@r607
NGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCANCATATTCCTGAACAANTGAGCAAACGAGAGAGGTACACCGNCAAATGGCAGCGACGCANACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTT
+
!@9GC(/!CH+"H?<$!G#;+F+59H>0(.&.1.*C;GCC?9H/-C#HE,5(*86::<B;8E1*.%<3A9C"F?-/)B)"4!0"#1!@#;):2@'#@><B+5$AC!F)"<'!'8&&46/0))96,.C?8/-A>!/C<285F-)%CG6B.#&:9/892/:
@r608
GCNAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGNCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGNTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTC
+
'!!/HB=)1G#G(.1&9('7A7<<*;F4<B(@#5'>#2#"66*?3FH7/3C2B??!E;:#-9$+$$0B-:>D(E?+$1"B0/D&35DF.%&8-.2$?+3"$G>-)?E0.=E1.3F!-;*&DA9(CD$!D02G@$.+B1E04=),F-13B,"?6,>'*(+??A*H.&-H,H;BB/G*@,.=7.<#!8&=<<!-EG"213BD?)#DC:26D.H'6E.#@>?<D9=64=0*#"*57+2AAG0.-<D!23)6,35-GAH$)<%52E714F9C0+>7,722?,.)C?FHAD0AH&G<@9#$2)*/B2;:82!'?+H,D7$)-=C1E0E0*9)>*C4-/?'829505A4E923
@r609
CCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGNTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGANGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCTCGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGTTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGNTTTGGGTTTAGCGTGACAAGTTTGCGACGATGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCT
+
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
@r610
ACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTGCACCGACCTCTGTCAGGTCGATTTCCCCGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCNCCANCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCNTACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGCCC
+
1/?:GA.:3)!H5#:H%0(3"8D?).5'&"($))*6(-*2%?&@*2$BC?FC%(3.-9#H1E!!&7==?:FC'F;-D)(E$,9?:C?D&%(GD%F52<!1;/>D@=F4DH4<C*15:-/A($@2H3:+H9)!>9"(4'.1#+&4/88,<7+,?!3?.6><'0!'9")8-5%08/-=08>A7/E9?C0G*A@$;58)9GE;C>#(?%.H'.?8-**@$FBB5</DE*.-;2%+GF!$2),?AG$!0C36?'
@r611
GGTGCAANCCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAG
+
)*%'%')+"'!*"&((*+%$'##&*##"#)*$*&'+$%*)(+$$"#('+!
@r612
NANCCGNNNNGNATTNNCANNNNNNNCCANTNTNNCNNNTNTTTNNGCGGTGNNAGNNNNTNCGCNGNGNAGNANC
+
!#$$#$$"#$"""#!!""$#!"!""!$$#!#"$"#"!!"#!!!!!!#"$$#$#!#$$!""$"!"$"#$#!$#"##"
@r613
CGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGNTAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTTAGTGCCGGACTGTCCAGTGAGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCNT
+
8F(/D7/;?B)$/F+DD4.,+@$-<9?4-F#;2.F=53<>+)70B=9;)(923FH);2(D*09',D='F$C7+,,C'"DF9$G5EAG:;="0B"1+3:E&.!=<(55#!<..H71!?$3&B!,@H.,3-,.%1B1+?#1$8F64$62(F?<HF=&$*.E/7/56"@E)/3)>@&(;3?0B%9"8/;D!C#>@-#A%$),D2C7C628>%)#!0).0B*?5"EFE(*';8'*-G9(H63C3BC)8,GB!#?@/"A$<)H;='F3)#:FH00<#+-E3.0"E$D=2;&H;C5>13
@r614
CTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCANCGGCAGCACCGTCGAGGATTGAGCTGA
+
A"B==52G*F8*"")9'."@;B%-+=/.G*,9=1&3H4**)5,D/2)%E8!81!<:H9'AF=+)*C*086/9()!DB9C$@*)5&/7!347B<;:3)@-F@+B=0C2'%;G7230?
@r615
NCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAACGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCATAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGNCGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGACGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCC
+
*8<$F&'?&?>8$:*3!4H%A4.659F!2/!610&6<A)4A-@68(!;$;#&3G&D8-D//@"6)H2.>A51+?&,"!./A%B5*6D>5:=C%*5;'"?5'!7H:D68A#B4@$"D%3&=GF+$/6-"8-8+(*-=C.35=C$!3E><96?-#;C@&@-':+:4HF%G"+4##%1/#(#,#B*9:/4FG2!HBC.66/4G4#7%&43D8+7>.$/2C(,3@.;$($4&0AG=4,3?:A*:,G'??,%-,,)7#F<>5;55@-FF30(H4;AF%-H/4$<,2!!43;8A?,E=2+/$!;56</78>:;DG0G9.!:$D)D9.+5(E97-3,*.4&#>4<.."=DA!?:A$-B:*;862!A6!*"#9G;)FH-3$<-!?7)-4$""9?G512+270?&E2-C'/5H:6
@r616
TAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCATTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCC
+
>0G8C'&%GD>;;4(GH,>!03;7@!.4.D>)0'C"((:8)?-@#A'3,-/A?;3,7H*9?.*,=A<7/#.9422,+,1HC:%GG5-@0#"7A/$%@%*>:H=5@"&;>6@@=7'7AD':3(28C+!4$7!67DE&B7):H7H3)"68F#E&&59$'G<271#(DA>.F3C.))6,H14E:!>/%G0,;=HE!A2)%.:8A,(F/1?B+G$7"8;82#-<'>.;(/0#C7>
@r617
GTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCANTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGNCCGTCACGCTTTCTGAAC
+
3*-';=%">0,4H4$)%GF=+-!0:'811$F,;CD##!CG.6:+8#'2368:BD4?@E4698H"-<B+*8!3$<*"BF<H6540%#.(63'9?:.;<2D+(&07>8G-D3"8/#%-36*3$4"#(F02%8;;D5.3/G9'"5=*@H>?6GH1>)!1:!574"2##&?DAH#9:;57@8%9G'";5
@r618
ANTGTGTTCATTCCAACGAGTGAATACNCGGAGCAATGTNGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCT
+
6=+F1:&/?-@#=,G8(D(&F:'('H>6;A9BE4?#8@=%=$'.(.GCE/-+>9-'%'/"3/>F>0:/D%!8<;"3&>$;>17>3?6DE
@r619
TTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTTATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAGTTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCN
+
;<F,64$?#,2@:52+E?53-:(69)/2A7,:;;C8.3C8C11;/B0B4:"4:4/H8F!4@,+&2H"B.5<)C$G"=<75=@<?;%!FA*+'6124E@16E#,2H4&B&;B$5$=*98:H4EF;=:2$7."=(D0.2,,7F<BA<9FC:/:F;F7B?B6,G+,>;EG8@(99>'E50';:B@+<@0)<H/C0E1BH7G-%A(@'71+GH2@(?*+<))34%6%75=%,:'(20##>@@G$9>4/HF+0-2)#,40=%1+?C180$3*&>G'=)&%$8)6*)*85B*5D=>C!04=1!$&+&"H%(*-0*8<8(35H#@*%<:#>4'5+->%!%?FA33<76#C&F'<(#:&:AA3#<#23=+@-#:C3+C=:>673*.!C464+1/1CH4@BG-%),"'H/5B
@r620
TGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGNGAGCTGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGATGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGCGTCTGT
+
86C;H#9(,7<$?9E.G09-!&,?G,CG%E89'-!*$(&"=,E-,;%;A$F6;;<=%78GA7CD)>/0**)$G.G+#?C)*();;72)4$9*"1>E;/#D*2/AEGF%9+5D.G$0>?7!"(D<84C-<3G,A6(84?$E!"@B<F&E60D2$%3FEE!D=+CE.'4*,%@)1-H-)36B&1:C5/75>.2G0*H%C#%8F1.F:A(77$@<-3;4284.,99&92B@,9)3"F>;8&#:??69--F=39'$6)=F8?5@/.2>B)1%G-7H":;?5.3H(/3AEE+AF1&G563G9.G%5:/F%B#G-=<+%9&4F"@"G)<H
@r621
NNGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGGTGCGGTGCTGGATATCGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTNTAAGAAAGCAGACGACATCTGGAATCTGCGCAANGATGATTATTTTGNTAACGATGAAGCGCGGGCGCGNTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTNAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGNAGANGCGCAGGAGGCTTACGAACGGCTGCAGACGCCGCTGGANAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGANAAAGGATTATGAAGCNACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAANACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCTGCCAGCAGCGCCGGGATTTGAGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGACGCCAGCTGTCTGCACAGGAGAAATCCCTGCTNGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCANCAGGCGGACAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGNAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACNGGATGGCAGGCCTGAAGTCCGGCTGGATTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAA
+
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
@r622
GTTTATGCAGNGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGNGTGACGCGAAAAAATGCCTCGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTNTGTCGTGACGGGATGAAAAGTACATGGCGAGTTT
+
1&F)36%=",*A!8&A!$++*;A0%F=*06:,<F7,GA%5@>B5.7'24//-7<G!:<@$2/)'%AC+9="@B7=F465*.46#843F,;<057?<3%2=G7$5=HB$6"D8DG,A(.24-G7$FH8F:<.G&ED5/DA&$9'C4F&G.C)"7;+=BD670<H6#,#.A751D(5!&";.E&:)"CC6+46E$:@'GHB81!)'(%$=)H7E*F<41-$G*D)2*6)7!G40(
@r623
TCATCTATAATTGGCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGNAATTGTTTATCATAAAAAATTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACNCTTCTGTCGAAGTGATATTTTTAGGCTTATGTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGT
+
7/1EDG!16E+A6771F:;)>BDA*%@3+%>2G'.6+F+,.$*5,(8-0->592-H,8>'<!4?%46E:A4,(>+G(D4C+%B-5=9A/AA!*(4<+4A)6@@.';$'(+-/,@5:01%33$>C3AA:&.3!E-#E<"4#:$8AGG.5"8DA,0$*178H>611F:>:23,.*:-<#,F,3!'+D+D+4<8(H"5A='F:5%',0&E0H-$1&:@D"=+8DA%&=:-4=(0<9!<,09<EE#F6=>15@C30H#A8+1$<-0A"8<!'8<2AA5+$1B7<@9@9%<5@;E,7C<.#H<B45G0B"BB0#=GB8*)E5'G#2?%?G$!:H4F3&*):&-EH=%'-=@9
@r624
TCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTNTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGNCCAATATCCAGCACCGCATCCCACATGGCTTTCAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCCTGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAATCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCCCGAAGGCTTCAGCGACCTTGTCC
+
CA/4=#CCE>/)?CB2F9CA+1.GD5=@9#=,,?01G&,'.7)1.29"/!.)$*""G2!;F(+A7,10<&2$15;;'+254/FHA)D;?*)EH$74A5?3:76F?G.3'#"=/?&%D+EE7,(9$1!G3>;4H)01%AH<"H#FH)'0;"&-4;6!.>?C*@.#1A>6H3:.A6D>=407@<8=9.3;E8%#B!C0)40'+%;659/H1"A-+D>"H$H$9<F/!=3))F;7D@*:!1,:.1.H3=-428%D>4$E'*:=$;%@<&&8&-AC??F,=A96+%H&=A$6--@=.@-H.<9/=B4B,9<2F6.(>1G)@?9<:+66=HD/+D8?")1<F":6>*<-6'D.-@.$027/%DB-F=+&+2?-C$<2:5!+B8%#-!6,6,-)(:=&CE;2)><0F*,6A;D':CB<:?!=/!H11'5A""@3"24$C5A/>);F-2!:0,G>*:676*+
@r625
GATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCATTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGNATTAGGCAGAGACAGGC
+
BFABDE1B/-7.)#3C2=-=2-;B&;9>A/8((+CH@61G=AB58635=/"C4AF&)H<)::)%"<5=&G56$B*F"&E?@?)>A%,;0?4DH1(+*97;*'2/F1.4F-@)&%%14<G):&;9(F6?8,13*$31+H++3*$5A090)"58,E4#E(7<%G%2$?0=&GE</*2?>;/DF0<&.>2>2:C?%-D<2==:=7222@G!G99%=D@?9B)H>6;F(2(4%%GBA=
@r626
AGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATNACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCNCTGCTTTTTTACCAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTANGGTCAAGAGAAGCAATNAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCG
+
2;H1;5H/*#7F**2/,2?DDA"FBG,D4<<+)5&A)7&17%0(%C9E?3G:>G=@?367"7FE1F#+B52)AD@:=CC;F+<$)H-<A,,/!@C!A/$'>D(>6,:7"E5DH-51##3672?G;>$*"!16&'2!/>BE8-.!:4!8:)>D?44;,B6":."6H*76D$?C1)'$7G5/F?H,>D!:*/8A!0(02"0*@D-32449(53C)@7(-D98!!$+!1&'!F8C897A0H5@#,8".B!:8;9EC1/.609@?F!:82B!%6A@A8?%9;D6%,C/+*"!9A-)1GD=3B1E4#<G8-2<(*H:F>7*F'>F:0,8BH-3G?!::?'&H2EH+C:'+>.EC7>CHH06&A4D2=1:;*5%=((>7-0,?<B&<H.=>11?@)GB)+"=$=9B4%8E?0DC33.1&4,?$;84.3($H6F:0'7'@BG7))%10*"/G2G.1A4',)
@r627
TGGTTTATTTGGCGATTATTATCTTCAGGAGAAAAATGGAAGTTCTATGACTCAATTG
+
@.)B#A*6C",/H0>5.:)>/*'&'"#+F.@$-+(5C:?:"=C7)C7@F&4!.7@G=@
@r628
AAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGNCACAGAAAATGT
+
1(.(,#4:/@FA?0&6-9B=<>.+D(G0<1,+%!%0+$8A@/"&0E3$+2/+A7*".<*;0-53$D%).=<6<5+//?G,4-D8F9'4.%,?(>C'3=5>.@##(4";>DH%&/G>+,>)5>2.7(1D/14D.?@0BFE*:83),!?;&/81//,7H5:638>#G4C))A1*0D!A%B@D//>%-
@r629
CGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGGGCCGGAGTTCATCGAAAAAATGGACGAGGCACTNGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAAAAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGAC
+
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
@r630
ATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGNTAAGTTCAATACTACTAATTTTTAGATGGAAAACGNATGTAATAGAGAGTAACTTAAAAGAGAGAT
+
1&G8!(#%*5?/6E4/H%3'H<7F3$1*F6=;9E;,6&0)+(3C%!H>>,*'?0!#:=F-B@&<"%3F=29C/?16)+$F@G<70-$82';+%!.H7C0?<FG+"29&B?'./*'+#(/=5'HA1!#6-8(-1-GC?1040E#2%*'#.A3D'H=3(<.(3/5#H"+/(3'!E6D
@r631
TGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTNGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCANCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGNGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATC
+
:>&'!=$;=<DDF+(7,"!<7@DG!GGE=3=G1E*%;#0F=?,G#AG"7,6/";E'!3"3<<D+EG%0>4,,*/H652F"E%*(*)<:%)%.5H1"E+22EG7?%==14&@'6$'"A8%!$<2#)@@A+.GA%3.31G)>()A0@2<9$HE86,?:E:*A8'9C7."899<4)>1'%?;<..D/,)3<3!4-2)H7)"'*+0>>1$-E',#(>=@,#%'1F+'A2)(C,7&9E-C"%!&,47.,49F$#(0!1,#3@A!'00"*12/0@7;.8@1BGF1-C*=!E0)$"D8'9'*(5>?8%4=
@r632
CCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCNTTGGTATGACCATCACCGTGAACGGCGTTGCTGCNGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTGGGTGACCGTTACGCTTTCTGAACTGTCA
+
:$F:2"=BC(:=01?&/;!*A3&,?CC2+%$?1(D(92/2%--57<DC&*;.2)#@9/+14!BF>26F%C"*-D.@=E,37B?C.(FAG$9DG&<=23#:/"1/!%4DD*@.*-&A(4)&23;2':E-68A7)/8!)#5+112620,D/C@:#20H7*6(19&*D;#F=<HF27>30F(H1D$;,7A+%$%<=3:@)H<D?D!F#"8:8H:87(:>%G1)F>6.C#0.3/2=@@5>!
@r633
ACGACCAATATCCAGCACCGCATCCCACATGGCTTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCNGTCAGCCCCGACGTCGGGTCTGTGGTCAGCCCGAAGGCTTCAGCGACCNTGTCCACCTCCACGCCGGATGCAGAGGAGTAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCCGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCNGGACA
+
/5EE)77$+;=&6&5>1C@;F&%@,,8%/-<$D1=:>C6C+(68$E)H8D><%-DH#?*%7"62/B8AF4*>/H.B-2<>.4G$2E?*530"'&'AHA*//''A0#?.3:+:G#5%%!&B=88H&;18++(C$)C@D=+6,/'?A*B5';-17)%554E5>!**9B3B$.0+?@7/A:*4/!<0?;(?6>5;A'#;:"-G6<:E#7"$!C:@0+1$54D/&A7&?"5*F9#G8;#$/)2*D08$!D/H93$38,9E;&E#?D8C50#FF1D22B&?6G?*!C?(==B3?9+D<>1#6'G+#40(.F%84@&:!E16&BF28()"FF+A-/CH(:4FA$.$+4AB=7#8G%=$2*#*HH?92)-3G82#05-@*F@B'1&&>3HHD+:3<50@3E&-3D>)5!4"A;"GEAG<@.6/2B"@C<;FD')H0:=?$)-@?(5C
@r634
ATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCACTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGNCCATCCGGAACTGTGTCCGGAAAAGCCNCGACGAACTGGTATCCCAGGTGGCCTGAACGAACANTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCNATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGNGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGNCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGC
+
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
@r635
AGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTNACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATANGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCANAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCNTGATANCGCNATNACCTACAAAGCCCAGCGCGACAAAAATGC
+
';>-C$4E(AA5*37#;:;A"4*=6@""=<6'>6,?1:#3H:$6+G7&>=>B8"&.-*!/"E.$95-<E8,=10H8)3$AB!>0)7/8:A.'H;F6H8'7BC/&CH>,B74?*)23;*33>%6--05%7(=<<H5.DGF)&4G)<</15-432CA8A53EB,H=9.+/CC$=(:#E183A@A7,7%#;33F&$+F@)->56)&.-D-/,*A<&GH8;.F0CD@2;$+-#'*/B$5%(G9;.:F%G'7A+4#9%")'D(2H>HE3;0%%8A.>)-1@++8($=#3)0A"(<B>1'A"A=!)6D,
@r636
CGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGGAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAANCACTGGCCTGGGGAAAACAGTACGAGAACGACNCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTNACTGAATCCCCGATCATCTCTNGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGANTTCATGANGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTNAGCTTACATGGGCCNGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCNGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGNCCTGCATTATGTCGTGACGGGATGANAAGTACATGGCGAG
+
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
@r637
TGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGNCAACGNATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTAGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGNGGACGGTGGTCAGGTTGTGGTGATTGGTCGCNGATGCAAAATGTTTTATGTGAAACCGCCTGTGGGNGGTTTTGTCATTTATGGAGCGTNAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACTCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGNTGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGANGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATNACCCGCACCATTACGTCT
+
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
@r638
TTTTACNCATTGGTACATTGNNGTNCGNCANCNTNNCACNAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATNACGAATTATTACATGCCTTAGCTATAATCTANGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAACTTGGTGTGTTGAACAANACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCANGGCCAATATCTAACTAACTAGATAAGAGGAATCGATTNTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCTTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAAT
+
%#$('!!)"'&$$#'%*$#"""!%&#&#())!$'&!()+#((+!+'(&''&$'$*%%$(#$%('&&%))+&&"$'#(!%&'*#($*$++&'%&!&))%$")+'+*(%)&$*)&''(#$&*&+#!++($&'*)''(#$&+#(%())&+)+##&&")$'+###(&+$$##*)"(!!'*)$!"")#$+*%+%&%#!"#$%)&'%(%"%+"%++&*#+*#"*+")&'%"%%"$()#%$+&#%"%$(%'(#((&#!*""('&%!)"(&')+*#!$'"$+"!$)'")+!""(#!&+)'"&$%'*!')&"%%)%)'*&*$*%*!)+$%&$)%")'!)&*$"$(***"*'$!*&'!)+#)$(*&&!($*"*"')$'$'"#!"+$##"")%))'#+*+!($)))'%$+$+++%%!&+%$#&+!*#''*!!+!)&&%*+#"!*%$'($+$"&$&*(&%*$!(#"+'"()%+'&+$%"+(!%##%(*%$#!$*'$##)%(#%+$+#(*)"%$&'($+&"#(%+%)*$!%'$')$#%$#"("'##)%#$&"&)&$%!"+"#'+&+$%"$"'!&+*(((&)"%$+(('&$+)%"%#*("&(!'*&)&'!&'($)&&(&#$%##))*#))
@r639
GNTAAACACGCTCGTTATACAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGANTGGCGGCCAACANGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATTCAGGCTACTGTGTTTAGNAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCCTGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTANGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCCCTACCANATCGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAANTCAATATC
+
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
@r640
ACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCNCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGG
+
7!3C!$/EC?:;(C.',B@@,"%A25=<!738-2#02/%;D;$$8./%3'B!+?E/290464!C5->0;09E8+F*46!%+EH'6-1:03F.D>=/7CBF56//!7#"!0*$(0;G2G12945D(--;<81(*2&$(&G?-8A4B8='"&!;,2%6!7-,G+0?D>95$FC>,7'1.@E21580+'"5<GG+C53=02D$07</73"-*==3@
@r641
NTTAGTTTTATTCGATGAACCANAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATNCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCNGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGACGAACCGTTTTAAAAGCGATGCTAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATACAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGNAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCNATGGGTATATGCACATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCTGGAAGACAAACACAGAGCTCTTCATCATTTCAANCTATTAAATATTGCTAACAGGTATCGTTTG
+
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
@r642
NCGNCNNNNNNCNGNNAANNNTNTNNNNNGNGGNTGNGANCNATGCGCATNTNNNNNCNNNNNCATTCGTNNCTNACNNCTANGNCNTTAANACNCNNAANANTAANATTATCGCNNNNACTGNTANGCNGNNNGTT
+
"$$"#$#$!$#$#!$$!"#!#!$!#""!$#$""!$$!"$#$$$"#$##$###!!"!"#!!$"!!!##!#$#"#!"$#!"""$#$#$""!$$#"$!"!"#"#"!"!!#$!#"##!"""#$"$"$#!$###!$!!#"!!
@r643
NCCACGCCAAAAGTGAGAGGNACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCNTGCCCGCATTGCGGGGAGGAGCAGTATNTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGCATGACNCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGNTGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTNGTTTTCGTC
+
'5;=3,1&*%@+'D(>6=>-:?-2?2:'D'F7+;F?!5'E>C//5-6/BC8C"&/D2'E;2)?+=<E9$D?:+9!;/!,5F=5-FGE9"&@B&F%;%2<<-=A$E<DA6E5/A5!:>?:';4));,7EH/;7'<'8#<39,*6E)?==>E#F>AB$:A?60"(09D>5=G$(D:"6!D;;E>E:(<9=*<+!#D?:#=%!;!HG+?#+,";G%=)$1A6#&2;61,5$CH0B9A;:3@*52>?;C-?0ABC,3F+4&@$+9!6/BH"!(1FH/:F;5><=AA(D&E:)A?DF,C':
@r644
CAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCTACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTT
+
/DE:/8!/<.A;(8%D($#37!A,"*0BC66<D/2E-69F(2,+H:*>H2/H%?/CA'6<"#H+,D0H%=D':-"+99*CB63G$?-D&;:6-,*&50D>C%B@<%>B4?F3A9A4:B.+&'
@r645
TAANGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGANTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGCAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTNCCCGAACGGCACGGTCGATGTGTTCCGNGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCC
+
+%!+*&('+%*(+&!&**"*"$%)"$%%("+(&(+")$(&%"%())$#*+#!%!'#%$&'!)+&(#++*##+$&+&!!!&#*')(!(&#'(("$(&#"$)($*#++*"&#(!))+%)'+&#!!%"&"#%#+&*!&%$"**!'"$!%)#*()"('+"!+'%"%"*!"%'("+"&(#**#"%%*#*%"$$!''!!(#+((()!($+!'#)!+$#(#"+"$"&)%)(!$'("#"$"*%*((""!&$*$)'%&'&*'***)+#+"'!&$*('(**!%$*&&'!!()'"+'&$($*$%$"%++!+("'%"!*'###!(''!!"(+)$"!)%*%*!(+$*+!"**#(""#)#!))!#*'*('"&&)))$"&#)'(#&+)%#*!!##)+$+"*%
@r646
ATGNCTCTTNNAGNNGNNGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGATGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTGGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTANAANCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATANGCCAAGTTCATTTTTCTTTTTNTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCNCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGNAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTGGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTNCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATA
+
)%("(#&(*#$$*!!!*!%++##&(*!($&)$%"&#(%&!!'$!'*(+()*"+)!)!"#()+)&!(!+'$"*#%!$#!#!+*&'+$'&((#+*&'!)"%"%"&*)'#'&"+"%((#&#$($+)!+'+%#!!"(''&#$!'(!%")$**('!#+!)*$'+%$)%!$!"'&*!"!'!)&$#(#$$"!&("*)'+)*!$#$$'%%"'&*%%+*+"*+*"%)#**!*#"&%'"&"!$&%!$(&+$)&"$(%#**!!#(&%+'('*$("!&*'#&#%$)")*&%+*"'!$&""(+%"')'(#'$$($'!$%*"(!"***("!+"&'!*('*''%!()+#'!%(*%$++#*$**%#)((#&$+#+&&'&(**%%)*+"+$%)+%**!''&$!(#'$'"+(&%('!%"++##$$**!$!)(*'(**')"&!!+&)(+$+&')&#'*')%+"$)+(+)(%%&$&*!"$%)"++!)**$"(%$"$#!$#*!!!+%&*)%'+"!$%*'+#(%)*('%$""$&!""##*))+)%&#*'&$('&%#$'#(**!&'%')*!("(!#%+!()$'&)"!+'*%&*$)%*+#*++!*$"((!)$#%%(&"!)#(#'#$$'("&&+*'##'+(($&##+#$+'#))&%&+()"+$$''"$*&#+*$&%#(*'!#**&&'*''"!$&()'#"+'%$$&)&+(%#+($#*)&+#"#((*#&)&'"$+)!$+'(!+(!#&&%)#%+!)#!%%#$%$"+&%()&*"&*+%!%(%"$#&*)+"**%++$"*$#*"'&+&+%%'%#)#$"'$*$"$%&%)&$++"+#$))#"$#+('*!*)(*("'!#*$'++))&&"'"('+$%"$%')+'%#"+++#!#*!)!'%$"&"*'%"#'$("+(''&+%&&#%#"*'+'&""$*!%*(#*(!)))$#)')*)&*!)++''"&(')%')#$%$#'+%*%!)'&#%&**#*)#(*$"+"&()"!!"+*%&&*&!&%$'##")#$#*%"+!&'))'+!$')+'&%#%+%%!++%(!+(&"%%*"$!+&((+&"&'!###'*"$&#)+(#+*(!)$*"*&#("$%((!'($!*!$)%$!)&$'*%*('#!*&$#%"$##('+")&#''"&)*!+(&%'+
@r647
ANTTTGACTTCCTGCCTCCAGTTTGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAANCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCTGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGNGTTTGTTTTTATCTCGGAGATTGTTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGNGCTTAATATTCTATATTGTGGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCT
+
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
@r648
AATGAGGNGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTNAAATTGAGAACGAAAANCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCNAGGAACTATTGAGTATGAACGCCNTCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGCACTTTGGTGCTGTNGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGG
+
?BFEB<:&8"6!/EG!;49%#,5@F;>$DH.>0E>,7G:6+%629%;<8)7++40733(!C6A@$&)&8>135(GF3')@!/!*:&5"D$*'%=&1<<&B*<1"#,(7A-;B,9#8<(/*1D6'AD*2E/:*G8CB'5(=.+)3=;<E+/(5./B=:'C3&,621(+3?3,)6=+<2*C%97<!/9::;:2,$2?H+HE(7;:!,?694(">!"&<9<%4/"C><&@/(&&2?H$'<9*<,?%:-+0$F9A#%9B9$40C6.>)-0,:A(-/0$8.?<*A@0837
@r649
NCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGNTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAAC
+
$=A?EEA;'068"#A'F2%C<'<#:215C,5A!%=/H/D?A4;/77$:<"75?(09<!75!4@%E=*567:>"!+"B04C.'F%04?G"@;,;)??9(!)>GE+H),4H0.05-A'3HG9HE@-=5G<?C<C.()#A).F/738H#0/HD$>%691,8;6?H;!+':(7!,5>?$5%98"F4+2C!?".HDDA'2'E&3<30811!9&A(%CFH#H7+5F,.*+=!9"8F(#A7%+34!6&.&0A?093'FA*/C"?%4C@"6$->$"$!,69($=7?7//#4"-600/#F(8<>)&-+G%4&'*CCF/-G2*-";9?C#9=-6A(@<,*#,09!9"3.A##F@5H-,*B:!DA6>2!EF;F,!;82'
@r650
TNTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACTGTTNCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGAT
+
#+'@*(90,)#!"AA9&5-?%'%EG$0(H#<>:*H@66==&"?$D$@%:B#9+-=#&A".C.BE89:%225.3863@$%C2H37$8%09=7)@$369C&&9$;00.A<0@#*-+A68%&2>'!D05705)2
@r651
CGTCACCTAAGCANGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATNGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACAGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCAGGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACANTCCGTAAAAACCAGGTTCGTGCTCANCTTTCCTTCCCGTTCTTCCCTGGTAGCANACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTCCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTA
+
7>23;A.)-'2)F;6G1+8BC0(5.*FG%1+89B#79.FC6<GE4H("83;(+@&A,;9;*(-"A",-0.<+'8%(8-&<A>C09*?;*0<%2:G)+F#!8#E5!/E9B:A0/C00B"*9;(>77=,'4D0+@=)0$*5:B362<"H=+*80#<C4&F,.!,G9)>"*/!"+*2<81/<.52F/96G#0:2E3=!+"7-</(1G?(!/D*(..+=*9-DH)H<5G--,A::>?""!/D,'',2;B,A%9-F)?;05>F7:8:2=G")%"G5E>,GG3:!A'+*F=)58&.@'"&=22(5<)19<>56,4C&=1A/=5%FE#.+"-5C.)8G(21';<&.G.?6<)AHB&0HA.&*,H$ED,H#'>7",B$50-2/8GB<7B%$;E.,B9<A=>;;16)"7(E2E&H"C-!?C0.85F(;7505/%$>BA:)7>$%;FA?
@r652
ATCCAGCCNGTCAGCCTTTCCCGCTGCTCCTGGCTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGNCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGNATGGCCACACCTTCCCGAATCATCAT
+
7/.FA(,0C:&8>6",53:%0'>;=2.DA6#A*:6F#@80F26D&H"F"'#:>%/6;;3=-C!,>CE93H)'1,@"+.AH/;C2'1(@"%+D?/#8C+*80C(+>4;5:E7;3.*0DE:86+?9$,%G'>-$#4G6'F61GC"5(9C(),$-.97!)1BE=-5,96@-/1A.9(=*#<*H#869&G25-!B4%>BA,1B'<;>70B=(=08%;(#9?9@<F9,..*!0@C)A/.305&B6+<*4FG>1HB26'87=!,&;<D8$%4?DFD,D:-90F2);&G(8":-/5A+0+*#>@"@DFH;:5#68'08;AG#&>H,&/*00%1.-2D5/!@9H,',D@8-287%7F7G86B?#-G'$2F-""@71D3A/::'&5C=<(@?1#(.H4.&@!;%*;&0B.8E64)*=?4B%-6G;4A16$,C5<;>)&6!6)@02A+!D,+:;B8+$@BBAC214.DC;*FD-FF*D;>8#'0>B5#,CC!GA7<EH(;$0<63=H+E'3'BG*&,6>>-=@8559=DG%08>7<<
@r653
CGTCCTTAACACCTCATTANTNAGAGGGGNAATTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGATTAATTCTATGCCCAGCACNAACATTGATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTNTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGANTCAAGAATCCCAAATGGCTATTTTCGATCGCTTGTTTTAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCNTAAAGAACAACCTGACCCAGCAAAAGGTAAACAATACTTTTATNTTGGACTCAAGAAGGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCAT
+
+%(%*(!%"#&"+$*)()!)'**"#%%+%)('$&+'++'!+)))*%+!"&#%*&$!)!+"'&##+"*##!*+#$"&)+$*&(*(!*&*"")(!#)&''"))++)"("&'*%!"#(%*!!$#"#'))()$$'!(#%(*)($*("*##%$++&(+%&+'+"(!*$$#"&&"%&#%!&+*"$+!*+((+#$+")+(++*)&"('*&$'%)&!'*!#")!)&&#!)'$$!!!%)"'&#)($#*#!(%*'!"!%#'(&%&(%%'"'(!#()+%#&)%("*&$+'&!'$"*!("&'"("*)!&'((*($!+%%$%&"&'&)&'(()+"'!%%*$+*)'#"#(&&&&")%*"!(%&$**"*'##+!!$"%**&'"(+'#$"&($+("'!#&&#+%"&*&($**)"%""%#)$""%*))''&%!#)&($($)$'!+'!(+%("'$(*!'('*&%"$*!)&#"*!%+*'$#"*&*"%*(#%&*+!+#(&")$*""&"'+$"
@r654
GTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACG
+
*577,-'E*('2G%F%92/0"H(47&3@;3/@?5,B!;1E<F@
@r655
GGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGGGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACNGTTGAGGANCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGNCGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGGGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGTGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACA
+
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
@r656
TTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGANTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTNGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCNTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGACNGAAGCGGNTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCTCTCCAAATA
+
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
@r657
GCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCG
+
(40)/E72&3E=6=):@<H%!3*)H/5=B0/A(%49%F;,F=6F$=)#'C:.G:H++E0D-DB($7()B*/")"74H/'%6FG-8#'@26'4@*>/G&:A*4C;=/+,+=167)DD"1D,@.(8A&;4.8@?D":"5@5-H&5=&=BBF&@-:'+$'$-+"?*%!4+DE91;&A,G.1(>
@r658
AGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTAAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGTTGGCAGCCTCCGGCCAGAGCACATCCTCATANCGGAACGGGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGNCAGCAGCAACCGCAAGAATGCCAACGGCA
+
+#+!'#+#$!*"'&$!&%"+*%!))(*%)+$+%%%$))&*+)$()$(++(&%'&"+()")$#)(&((&#")"('$($)&*)%%&#')&)((**""%$#"#''$'#$(!%%'%'$'&$&$!)"'#%*!))'#)%(##+#%))'"+)!%!&*+#!!!!"$+&"##)')$"$%'$%*%&$+&!*!&'&!*!)%%*$(!#!'(
@r659
CCCGTCACCTCAATTTTCAGACACTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACNTTATCTATCAGAAAAAGGCCATCTCT
+
5/$=/*-83:"#%&#6'6&/-24DBE1144;D3E&)ACAF=C4'C9?*3G-&E=&.'1%+;!6$B9<)9$(:DD5+-;#'<A(@3#+@;1GCA9-
@r660
GATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTNAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAGTGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGAATCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTNTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAACCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTAATCNGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTG
+
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
@r661
ACGCCGANCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGNCCGT
+
"43(1#2A17H'C"3,*+="G3;<9F*GF913,2F09>)6B/594-:A!;"#<$1=(75."#BHFH><+<19*48:-G?*>-3"G51DD<:?54-%HE54">*H18'+;/A-E?!;1$>A*9F-HC$/#F3:H8!17.E);,,)(C,2B8")&>H:10>H..98<+0B;?=$G!<F/E)(B5(<5.7.*4%A%7(6>0&=#AAEG+'+$&C+;-A-0'#G=G0,/@$=!:!H9C=AB=#<D.EC5/(.?F&0D@2=>8+G)%,8H7=#(.
@r662
CTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAGNATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTT
+
G!'-F2))0:-BH1(>+?)5<'#/5-5C(%:D6>D(,-C&7D.!AD*F@ABA*G43-F:6E+2,4AB%A;6+9%G5D%)B==999#7@8$A5)(>:7+;3*4B"@8GG8#@H.F@"1ED;EH&48#&7F%*C-;1,,DA)">64$9C3;#*,BD=.C!7F!892$491CE5D/H!F+0&5C?=?=A8..A6#7+
@r663
TGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGCTGCTTTATTTAATGGCATTAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGNGTAAGCACAACCAAAAAAGCCAATGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAACTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGACCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGANAGCGGTCAGGTGTTTNTACNACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATANCATAGTAAATGGATTGAATNATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATNATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCG
+
<9@F+$?>E=H!$/)%"009EDE6?4(%%-;42:$!BF(@FBG'<:5>,&<D&/3>4A/H+F7119;@3/>7$9)/C+!6<!?9"E<<)>56#@,5/EG:)504:E&()=<D!0("E,C#9*D5%<BFD*;E6@';>*8,97@,4$E*4*09&#-<%$?8-"2E#-0=.C(:2?2147"B;,0(3H396GG32$A+369E'D82B3H(<3>&?9C62-4."/:!"D)0$)/-8@3+$+/&D4BH3F1+>F,3583++,/)78>D580:DA/E*1?E146%(3,#C,=(B>?2(!<@#<7E4E@%*+#!-#-6H"'$BDCAHH2>/>%B1(7A-%4)%"+"E!AA(,98&"H-+/#27&@C*!3#E00<!)05+/@*1>+.@/=%+*F/=#!+83367A.3.E<>F%,?>6@2A-E$E5;HC<$9'4<D0#G5(#*E<)/H<8E(F+!*DG8C*391!832AD-5BD2,>$=5<#<E!<HH59E1>:1=>*F4@16$,7;*C<12+)=)&9ECC*4:@<2("GA&)70<C)>4A&?3D4>%4)15-:4=73/EF"C,%*;.D$1*?F$!=-D3!522$!:#5,F1"F/-(27H3FE2E43#:A83A-$C;.(61<*A;!'@F1H8(>*C&;>F5*F002=/C=B&>$4!"+E"&:8C*5@5#00>77@-/AG=D9E5/$HE/.A6'?!?"55>@$5?F61(,%-1"0C39B3BA16/.4?@5:2:(;=<:!=A!-11/,FADC6B02:/),)=HCF'%E(<-A&-C4D6&"E32#;1#-+)#(-14/%=<3B'8=F(7B$*FD1E=&+C++&>%30FA-C&F8+8.G3*DB$AD$$>A'"(!-!1!H=AC412/#EC/(7G$8B%0F)=>=B;-C3:%H%5"8.@9",FH6H6(/7<E+2A6C5C&0B"G,0$8)C,8&$>$&#>='#/2/AC,$+/:*A24<;)"?E!)/4-)--$9@51?7!##?'H&8'"9-<%DD2?B).>F6*#4>%D>%=*9=#<'3E%3;H""@.+)D8?..(9!4'B%;-C&,;F)A="BC"89(<B).2+='1
@r664
AAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACATTATGTGAGCGTGAAGGCCGGNCCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCANGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCA
+
BF0,@&@=C#")AG+32(/$,E<@@B1DDGD65E$3,@E1D(5EG3C;509!!6+66/&63H5-4.1:C%#H=1*C:&/+,>/9/"+7/E9<C$$%/4:6@==&87?()-(E2686=C7409;;&483%-;3H,?:9">?**<:=?',75B:=##:7&.2H?HD*$E=/3")0(9AG""5*AF)E:(3&;G%--E&/@0H00')4E756,=.A(G>3%0(8@!4&06(&5,B:4:F58B=09:5G'(<3#*"$?715";5*@0
@r665
GCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGTCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGAACGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGT
+
;!2-00,9#82B34,1/-E0:G<;.B"B894$=C?&A>F"4)12%2F'C<(2'67#/#./4.@>4:-D$D13:6$.,E@(H+&A#644F)G%&#*C=F=;E0')DH8G8F.F70#E6<1CB#.+F4=9!"9E8A@738,>3'BC12!!*9$69-G2"B7*6'7*B6!G-'G!5/%=$6<,DG6E-77<"#(4D3#-'$%CF+%>3%"G2;8+4@9!&1;3/<7;(;G/0C1/E<;8+.!@
@r666
ATTTAGTGAAGTTTTTCCGCTGTCATTAGGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATNTTTTGATGTTTGACATCTGCTCATATCCTNACAGATAAANAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCANTAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACANAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACT
+
"*!'$*%+'$+(%&*)%$*&+'*+!"+"#*'"&(&#)%$%"$!"")*%%))$$")%)$#+#*&##%$*()$*"%(!%%+#&$""(+*&*%!%"$!$*)(($!$$!$'+(&"(+"&"*$&*&""$&'+"($)$*("'(&"%%$+)$")*#+("!!%$"%&%%&!$&#))(*!*"&)'%$$##&)'%&$)!!!"!(%*#%*#*%*'')"#($(&""'*(&$*##'"!*&''%!$+"*!"$'++#)+$*')&'&**$&)&""(&!#%"#'*"*+&++'+!%")
@r667
CGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGNGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGC
+
?2=+/.BCFFD(E4##C".(/A7>(A73*30*%;$:)$!=*6"9-?(0*B=G8<&?@'>4>",)?H>E3G0=&?-,F?$7!@344#%-+#%>A(CDG45-;?)G'3/,?1D/#$1D.61+G&D00H&<D$6EF3//4'A#*E7*.8DA"2591<@;D855<)4..:>9,8-EDBE?>0A)8)GG?+=#0>A1@/):.0H8
@r668
CGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGNGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAGCCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCT
+
=90+91DB10999&GBC3B<!F7"?$C0-6GH8B!#5-%B83D9169B,50')+.<)6C(+3*1(;A@+E;:!."''5:5=)'B<G)8+*#/::7)?0F));?E<=6?%-=6.#(H&%D.>2G.*%%/(5%2>$%E6%6D$#
@r669
NTGCTNGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGAACACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCACNTGCTTTCCCGTTGGTGGGA
+
+&+*+($!$*'*$*)!%'$$&$$)%!'$#&($'"(&+#$+$+$+$(#!#)#(*)"+'""()&*!(+*()'#"*"+#&+(+!'!("%#!+!)!'%)#&($$)*((%'*##(+)#%!'"$+*$+(*)%##!"()'"#("&#&(&!+)(#"'$*"&)&)"+!++((+*#%*)"#"')++%$'!)*+#*
@r670
TGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCG
+
H08&=,(&(+(?-<5,4,>1$*,,)78CBE+&&*7+=9&+44701B*C5H?D'F@@7D80<-)%.1>5E/H14&#G&$)?=@)=.7$,C@$8.6ACC=/6%+/)G$)%E609F2.E&*!.2%:D)5@D,;61<G=,5F@/B-$:3(%7
@r671
TCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTNATGCGGAAGAGGTAAAG
+
99-+'0*#+#<H'07G.*D-60:/.-H!,H+4/*<?0)1)G)-%?&.::6<69.H7H20'BA#%?!4
@r672
CCAGAGGTTCATCTGCATCCAACTTTGCTCTCTGCTTTTTT
+
D57C!3&>765D73H%D*-4882125,+($!9F5'#.1G;/
@r673
ATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACG
+
.,#9!>H987'"?@173F,A)+@0B>5*=C/)CEAE$1:DE-6@7E17,9$
@r674
ACATCACCACAAAAGAAATTGCGGCAATGCTGAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCANATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAAATCAAGACTTACGGCTGACGAATACCTGAA
+
?E0&G+2='@'=9;B=1F**@/&.68CG,8A74.BE-2:='<(<4/!7+'!@!B)6C;&6;=>,$C)D6D11,G6*F'37,-CA'+4"&:':,:-;"/$001)$;3<E971'-'*0,D"5#=6%1@,07"&&%$%3-6):-GFB16%*=%B4'9!&3?(+D%-BC==./>;-#??':26GB/EC8/85+4F=5(HG9F??2->?D;-8
@r675
NATGCATACACCNTAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTNTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGCTAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGT
+
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
@r676
ATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGTGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGC
+
C6=1/77;ED;F,1#H:'4660)/5+/DC?6=(E0;7;$2&*9.E8:%.(=@B4C0BF-FB3/G8?"!7:4/??7DA<3C&9&C/(9<FD=,D?C84%,%?)9B34/%HG'EH&(-G%.+-?5
@r677
TTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCTCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTC
+
H%;G>;-C9C'/!BH#2=$,G!-)6*3>A9,C2.+40EA;(03!BE,5;H-D#@)EB4607=3E#?E%D+9;+25+1?C6C!7+<@44G0#F8)9$AG+09+<"'F%8BED?C&;B8H9:00G99?$'05AB#'+&G%4!;"4/.6:#?&6!*")
@r678
GACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGNAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAANATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTC
+
#BB!&;E(7;DC#,A-8>%7>,/E83(2:<0AF(FHH'E9#;6D:/HF#%8"3+486.,4C%@4&,DD>,3#-G9B+<;;,'"E(0>F+#9'HD/(!);=(3,D-@8-;C%&>*'A%;0F,#1,G,-"F7:)459#;*$GG)&4*84'/A*&5FG16@+4H+$(,0:/E<:%:%!@58+9E4($*=*C<CC-"#B-A%%@+?2*&172;<BE.6?*GE@H<EC1(%0A)+$.;?$.-#39>><,091/;+28:@5$+'(!;!<(-:'-)/@9+(H.2=<EB,>:1%82<H*5#-%&92>%'GC*?=;8;-/5)3!>!:E"?*%/)D:6-,DHD*&"4>$
@r679
CAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCNTAAAGTTCTCGGCNTCACCATCCGTCGGCAACCAGATAAGGGTGTTGNGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCANTTTGGAATANCCGACACGGGCAGACTTCACCACATTCACCT
+
(5B!0&HF868!+"*D"=3>H5B;%=%FHC<3@E3!/((?%!!8!'#&1"9/?(C>E:B:*H!*A3%>8(3F"4<?F";@/=%'*+.:#;B)01(!FA!#/"=<;8GG/9B5D67%$+GG288#C%/4+C.*!B>(D'75*+-6#5*+0:-H,3.</0;'":D/82B7='%D:/E=?DF"3)<!#
@r680
TTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCC
+
:D4)D!=)$"+3B$H:-@6:E0E/?,30<A"241!CF+2%,"=8;A?HD@5!!=AC:#9C2/2@>,$.<+,30=458A+%/51,9;/&3=3>%134.,<A%B"@1@>0.<A0,7%AB-EGC"E>9&-5=6<7?%9=.D"G#2G5!*!#-0<0%;3,2+04#E:"(H
@r681
GATAAAGCCAAGGCCAATATCTAAGTAACTAGATAANAGGAATCGATTTTCCCTTAATTTTNTGGCGTCCACTGCATGTTATGCC
+
$5@:9295+/%!A:H=480>+G:6A#FABF(<$'0<&"3$-6A;0./E->7F%GC5;D97")"/EGD./*-%&3$9*%)#8<>)D
@r682
TNTGTGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGNTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATG
+
!'"$+"'%&!+*+%*("!%%+!)*#'!$"%#$(!""#(!'%*)'!((+*)($*+)%)$$!%*$)+%!%%)*$$&#$!"*#"((##$$'!!'#")"(&!&!%&%*(!!'#+#!()*%
@r683
NCTGTACCTGCGCNTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCTACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATACATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGNTCAGCACGTTACCGGACCAGAANTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCCGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTGTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACCAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATANCAATCCCCCAATTTGAGGGATGTNTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTAGAGGGATGCACCATTCTGAGATGTTTTTATTTGNTCCAAACATGCCGCCTTNCTGCTTGATAATATTCATTCAGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTNCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGNACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACGTATCAACGCCCACAGCNTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCNTCGTTGCGTTTGTTTGCACGAACCATATGTGAGTATTTCCTTAGATAACAATTGATTGAATGTANGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTGCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTCACCNC
+
,';25"DH0%)%!9E@F806E!6&BH+(9DF@D!3&4A*:&&0$/=CB7B;*4,1+7"0C@382&2H($D0<H2AG%+-9*.BCH,>.2<+44>B<C%3+2!)3+39'GA5C;",.>+<!.3H$-#4=$0B6&=/(7B@-F+<+?C).B$H=6!11/@4A(A?D5E#$24(.,$A&@@&%93,4'HD,FC<=7C>/"D=G.6:59GC;,"8021!.%5'=#44H9H'B!609-&H.4!7+?2D%*B<!2/8/3H!86F7C5"F"(36,505<H;04))F>A@BA7/$4H64C=$&:7-.*68;+"<A45/EA5&G071;<C5;.,%3@HH;H:G2@$+D@F804<%:2@B+%!$G8,/;7%A?3%&H5>1'4:3.;E<!3%G?G=.9."A,%(D2E)2(F3$&>F,!@&>A94&%C2-FE<$C>+4%:E-<:%A62!.?<G0>E>+48,)<)7&FDA<5#4EABC2!G>.&5'!-G-3163#?2&@AF(:F%#/2")D?<2!@8:H(54((AA415'-193%2!D0A0&(=:=E=2<#4(-42E)$")"<2.B:!*@:)+?&=!-),@74G+"2D&BA,$2DA,BD$%*-7-?7'A"<5:2;$>4$'?<DFD/H6.A?&442$E2,;(3A,*4BC%?-":9!E$'%=8,;$D56>$;*%'"#9,<%:@A,59A@!?)/!G<1-%DG8=(<@@B*!#90<$3B28B4'236*+=0/@73'*(7"E:HG8<@A:-2H+D+!49=3/30!D58B@E9A,?1*A<%4>H$60>5G2+D&A?=,F*.B;7$<%%C4GC7-G2?7F#9$@7'B84<?(.24+2E#.)>??E4C;/@A:(#D=F)#/&AA5=$'0*28!%;':?;B?AF;4-@*2.*5<+)"+E'1!9E>34200-,=1!'78*A++.(0D*1D!'"93A,D@@25)B>2'#)<E20!5#23CBG+C2C"B?>-@%!?2-E!8,GC9B*5EC@E5&H,!2)/'#<854G,=;+D?!43#7*0H8GC&-6(C,58924,&C*FA8<%',D>-B,>GG(#,:+0$-:12(6@//<0B3F8&"B%;8?E31:AH5844</E"&$-/*H@""?F(D$?0(F/!A>.!:$7D@GC;030#.A$-@=54?,+8%H+&#+-7&?56?>+-<%*H!@BB,AB6G$:*3(0)+5@0D+5=9540;BB76F3?0;4<G7,.86@%=#4AEF5E:'7+6!=F'%.F%2-$E?,26377E@#5?!!#(+0?A!2#76$743A4=8CB8%4HD/($&4B3H4>923E:E2<',5+&8BG;8AE7>H111,E::.*@AD4%0GH&+CB!==G/3F)38==C2F7H>50:1#62)#BB>F.B#,AD0E<(:A$$*:,2':-%*>#',:@.39&4&5D@)@#38G>ECD/8!==AC*F$,:)/@3:*',88;B,E/3$82+E*:?-E**A+'5(+//@++B7(7D#0HG;0!%7'/,>#$3A947=H@#4+B-87G28(@5B/D&F+0
@r684
TCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGC
+
.<A0>;)0!..881!4&%;F9%G?D=>0G;;9:$()6)G/.@BC..!%B67/:8(0-FG4:D80+12>"79&(@$*/D>&?5328&DE8FCD<:H08,7A1'3
@r685
GCATTCACTAACCCCCTTTCCTGTTTTCCAAATCAGCCCAGCATTTCGCGGGCGAAATTTTCACAGCTATTTCAGGANTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGACNCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCGAGCACCTGTATGAATCGCTATGCATCGATCATTTGCAACGCCACGGGG
+
+3(-D"@B>!22C5F<'B!2+!.152:13CF,C'H=+)9#41B0%4D>C!2/=/#->.7<(FD6:E6&?##:?2+7&$<BE@@=8=&:12-A8C#B$-F"F:.=)9F.C@!E.)$9*4C-691"+2<85D<7$A0/27?30>F%4?1%)+61.9G1<&</F*,?C'52H9(<&6BA52905">+F//1'(C,!?)=87,092>4E/E;DG9(GF%,2?73G:?51;94<63@+20;*1?1G";.E<,EF09-E8
@r686
NTNCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCNAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATNTCCGGTGGCTNAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTA
+
"!#+$)$+)!"#&'+'+'+&'!#*#!#$'!'%(($"(+$'+%$()'"!%%**!)!#$!'"&+!"#"!!#$+"'%+&%(!('%$%$%"#'$"*%))$%'%&*+%'!*$!()+$(%$'*))'(&$((*%%&%$!*$'''!()$(!+#)"$!'+!#%$#"$"(!$(!+"&&#&+&)&)#+'%%(%+'+
@r687
TAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGGTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCAT
+
7%F-(*"AA!2":7,78$797:1&H@7#<H5-%A(>G;5?4%2!'':E0)#&H401)H6-(E32C%B<E!./18%5""@>2"1E+/E!B-'/.,7"%6EDF@):=:7)C4.?/*E485#,#FG<5826!)."-,<D+0/EE-D/#:=9:'F#8,(965:@)3;*41$=2*75)8/0C.:,0AFD!8.(7!/?2;511:;)F@)2;"(G#-7E2#5"($D+!(:/0=<69E9$&=$?51?:%-';1?$#<:EB(&$&B)##
@r688
GTACACCGACAAATGGNAGCGACGCACACACTCCCTCTGGCGTCNCCGNGCATGGCGCGCAGCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTAG
+
06C<A&C6A-;BHG9A'B1?':2H<A,;8,/*@4+,0%4AF3#)-&872#'8*F2B<CE!B##=%.+'>66*"+"H1#H<.6/.<G;B5>$2D+-9)8'C1*?.DF18&&
@r689
ATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTNATTTCTGCG
+
67%%ED?)B&04D"*2*6#4?.8?''5>!0G4GE<1/$.2DAD!?B1-07/0+=%.&2.4>:.@9F(+=:5".$#;HD+47@#4
@r690
CNNCNTNATGATATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGCTTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATNTACAAATAANTGGAGCCA
+
""(()&*&$)*!$+!+(+!!$)($(+'#+%!##%)"!$+%#*"(&+($$'''*%)")$!++#)&%"#*%+#$%#+*+'!'$)**&*&$*$'&"(#$$$*&)+(*!!"%)%%$"'%")('"*)(&'$#**#*+#&'$))#$(#!+!$*))))(!&$(#((#$'&")*%%!&$%'+%$#$()#*)%(%#"#&"+('&%#+)*%!'!$#"+"#&*'#(+**("'%*%#$+&%&)'*'+)$*)""&'++('(%)*'*(#'&)"%&'*$$#%
@r691
GNNATAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTANAAACAGACGAAGAATTTCATACGTNAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAAC
+
*#!0E4@G%;!C&&86F,A<0)$9)&6*BAA-H4$,2,9/0>B+B96B*F8C=!#-B%562A=3$/4$%(9H%6<5';$'")3H;.3B0C>A4?:#?@(E49>5?:F:50>#A);0GC*F!<,?F4?D*B7/%*=?%>+!#C4:='85D!?D4E)>$0'#35
@r692
TTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATNAACAGAGATGAAGGTAAAGTACAATGAAANAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCT
+
5*3!=;15G-8>7#;(>D>+!"4,-)36H>E/E5B9%5?'.0(5(B;8F.(.')&002G!H<E*?<507DG106>#ED(/&C<69"A84FA<?#;52!%F$#A
@r693
AAGCAACAACCATTCGATTTGCAANTACCGGAACATCTCGGTAACTGCA
+
(<G0*&-8((4&!9@3,D);!D?3=$=@63H@<9.B=@1<0A6@C@@?>
@r694
GATTTCAGTGTAAGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTC
+
+'?C6/$"7;G8465;,*<-;92!5=21>+1)A=5CG*?24:!=;93,0BB*;7EB)
@r695
CCTTGNNCNNNGGNACCANNTCNNNGNAGNAACNNNNANNNTNNGCNTANNNNTNGAANNTGNNTNCANANTCACCCGANNNCGANCGGGAT
+
"##!#!"!!#!!$!!"$#!""!!#"""##!$!""!!###!#$#!$$#!!!!!#$!!!$#!#$#$"!""!!!$$#$#$#"$$!!$"$$""#!$
@r696
CAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCACTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAANCA
+
03@0C&F!09,=;0G$.;B<25-.:)?"+!B-5'/E'%C'"+$6D6C!6%7E#A;)CG9<:/8BF&>94/376'?/9G+"0#'<>121G*'=:$%@#+D$=#C,9173@#585@9*B9&6B'$G(CH0G1@658&4+5H'<F.@.99=-H$74$>:D*7G72#G1((+=(/49D=2/!.FE3&:-5-1?++G,=#&,;=C"F2:B>A!.8?"B5-
@r697
TCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAANATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAANGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTCCAAACGCCAGCTGGCTGAACTTGGCGACAAGGTTACGTATCAGGAGCGCCTAAACGCGCTGGCGCAGCA
+
)2'@D2DF>+7572&/(G,-F#3>D"?C3-F01<"#'*#/??H53G'&94"0!.E):#;;>>2@>73EH1'>,)%?86=-@89425>;$,H*:;8A6-0.95D7-$E1?#065%A#$B4#F3:64G=>""AD?-A0!A4A>".@5@,,E#)+BF&H"*3/<!@653-@%)(DH*@%*#!6+#5,9'>D##F<22<915@,<9#*-)">B$+.&@E/.#*?B6;)57B,F@55+&!003+-C71G><,!@C:)%6):+<8%(2B*)9(=$.29'B$5=)A:F:35D#@()#BGE6>G:9%
@r698
NCAGTGNNNCNNNNCNNANGNTNNNGNNNNGGATNNNCGAANGNACNNCCATNNANGAATGNNN
+
"$$$$$!!$#!!!#!!!"#$"#$#"$"##"$$"#"$!#!$""$"##"#!"""!#!#!$"#!#!"
@r699
ATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTT
+
B*(<&?%@B77*5#%)>D8:<+B+616#;66=+6<$,@2,@%$DB?8?"5%>>B9--"3$>D7B&B9G5(7HAAAG?($+*-+.-F(50)A;E>;>5(DF42:7'F2'"?(1"(.
@r700
CTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCNGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCNTTCACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGNATGTCGCGGCNNAATATCTNGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATC
+
3H2*3/8$8D?9&0*.2;6=C*%G)4CB2.)"87")G5/4!0>/4-*->G-.%)0#3<+,>:?G"'%8:894C/&H1):+B=<++G038&#-6/D1/!;?,?C2&:9)(8B621>3F4;E';?>3%<4$F7&E?'E6F*;#&D*6%#3H+0G$5C/5;%3",&/G1!#62&D.::71>=?!0C+B4AE4%9<;*15;%>(C0**'>)E5F)/4'D''.9(?;ABFB%DC!F(/A<<6=A:/F30:129/>&.%(4:0)8>&"10*,(/#&(:C?@<>!$271=,)59H7:
@r701
TTAGGNCACTGACTAGCGATAACTTTCCCCANAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTG
+
($(')!+*'$"*%%)"**!"&%&"+'$)%&"*&)%(&%"(+$)"#++#"*!+!*")#!!%+!!(+(%"+++#$"()$*+"!$
@r702
ANGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCGTTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGNGAGCGAAGCCCGGCGCGNACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGATCATGGCCTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCNATGCACCGACAGGGGGAGCCNGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAA
+
%"+%"!$("+$"*&%*!$)""+++%&)$+$%'"(+)!)$''"($'%!)&+"!(!)%+"#$''$!"&%$)&)+"(&#()#&*+")""#$&%#%(!('(*'#)$(&+"*!'$')$$*%""!(%*&!'$'&&()*'(+!##)$$&#(#"*#%$*#"*+(*%"&&!!#+*$'&*#'""'#*"("+$##'!)*"#+%$$'&''&!+%*(('"!)%&!((%$$*'*''*$)$'$!$%+"''%!%#("#%'$+"*)!!*&)'$"#$"&!!''+""%"&+)#$%&+*)*%'"$"'")%#+("#&"$(!'()+&()#+$(!*!"&$#&&
@r703
CCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCNNTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATCTGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCNGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCNCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCAACCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAANTATCCGGGTTATTCGGGAAGNGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGATATAAATCTGCTCTTTAGCGGTATCCGTACCGATTTCGGNAAGGTAAACCCCGTTTTGGTTTCGCCTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTTGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCANTATCCCAGCAGANANGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCG
+
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
@r704
TTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGAGTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAG
+
/D!8H?04B$7.:56:F!D2#,G(9'1?F/;$%1/"-:38'G.!,+<!!3*B%8H39=C,%=4##.*@*35=.?F/-='6E)34:EDD,CG'8&!9"FH?*5:CE$"$-A0+:.<*4/@:#:<+(+G1G)F@A;=;4#(@(F/-HB<1!8)E75:E,,1)4;.,=87">C7AC)#?-/#!0GD#/)FH%0/AB2<##-A**B8?5"=:DH--#1*3,31876E5*8!@D+A,,D%5@./&"#@.FA/"7F)>1)(B+B):3*-!513:7$%F1"/C4DH841!<)A&DA25@H,+=63#;50>4+/"0?D?#?":,0D$9'1"F(2$!66D?3"$?F.*0'?+%>A!B%>B#9!/3+&16@:5G292@"+';$B?HH'@%1)"1D8/$>@%C
@r705
NAAGCACTTCCTGCTCAATCTGTTTAACCGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAAC
+
)>1%D76?63+$85#C#C//+.5E.H8&G&:2%/9F>,H+B(C1/""'(&''%9F/'%.??F7()/1&&4G09<#;BAH.H17F;*,09!>!H.-8,(?2:BE346CH0,=::>"'(819##+8+A;F)3%?FEF3-C<4G>;/%G"4%<6=-$D1+6,+%$)E?C8:+13.37:>6GE?7E(%:72$<3%/0(BG":8A.$%EC/!.;*!)9G(?8=G<'7!8)CH,4.92H@--:0D1B!4)+:G@F#.0A,A
@r706
ATCNNAGTNNNTNTCTGCGGNNTNCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTTNACACCGGCACGGCAGTTCNGGCTGTCGCCGGTANTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGANGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACNCGGTGGGTTCCNCGACCGCAACTGCCCTCCAAATCCGCTGCAACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTAGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTTTGCAATATATTTTTTCAGGTCAGACNCGGAAGTGGCCGTAAACTCCACCCTCCGTNCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCGAGTGTTTTCTTGTTGGTAGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCGGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCCCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCCGNAACTTATCAGTAAACAGAGAGGTTNGAAGTGAGCGAAATTAACGCTCAGGNACTGCGTGAAGCGGCAGAGCAGGCAGTGCATGACGACTGGGGATTTGCCGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACNGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGA
+
#"'$#%()!""('')*'"&*#!(#+$$('#"*&'"*+!!((()+&$"%&+#)'"+('))#)#+!!*%'!*(#(**&*#'!+(#*%%)+(#*!!)+$')"+!$&+%&+##%$)$#()#(*()+'"%!"('*)+(*#%(&*#""'!&$!"$)"!''!*'#!"(&)%#$*+#&!"!#%'&+'%((&&)*$*#*)'(%$(+$'(#+#"&%)(#%$'!+(%'"#$)"))+)+&("$(+#$*+&+!*#!"'"*"%)(*++(!&+!"'$!"#*'"#($!%#+%%'(&#!()+&)(#$$$!!&*+++(%)!")'*+')+)%%#)$!*$)*"!#'*)#'&%*)%+)"##*$)&$**+&)&')#($%$%%*'&*$(#((#&#!!$%%&$%'%*"+%'!##*)#(%#++'+%))&&*#"((+#)%&&&##+"$'+%+#%#$'+''*"$$#)&"%(*)(!+$&%'*"%%#(*'!*"%!*()&(#$"!&!$!++)!(*"%*'$)#&$)"($%)%!'()&'$%'++!))"")"'!#+!&(#&$!&$)$*#)()&!))")##*#&!%)+#)#**%)+%"'$&()%$##"!&*'$$%$*+("($!++)#)#)$($+%+#'+$$(($"'$!(!!($#&)!#+')!$$+*+#&%&'"+)$$$%*%&!*+#+)!++!"')+'*''$))%#&!""&(#%#*!("##&&"!(")$+'(%(&&!&$&!$)#((%%+)(*)(%$*!)+!("'))+*)+!'%!))&"#")+*)*)'$"*'++#$)(('+$""+!'(!+&)'&!+#%%$)(#$!++)!%$((#(#&!&#*)"#*&%%!$%!*"*'*&#+%)##")(%%$+&!(&$&)&+)($"*+'!$+#*#*)#)+"(&&"'#)%+#(+##''()'(&!+&!&)+&+!#")$'(($$'')"**)!$$"(&$"**$!$*!)#$%&#$'#$"&'&(('%$*&(*$"'!(!!(#&"'$"!('''*%'!%*!+'(!#'!%*"!$&+&%"#)$#$*(#%&"%'$#*%'#*")*&''&"*&$#!#+"&(('$)!&"*((##!"""*!'"%$)**#&+"!$""#&$#'&'+%'$)&!!(*%&!)!*!**$$"%!"*+!(!("&$%+)"%('&+#(+*%#*'%+'!)$&)$'+&('"&"&!))*(#(+'#$+))''!#'#'&&#!"+&#$+!"&)!)&#"(&'++"!%()'!#((%#)"(%)"#&!%#(*&"'+('+$'"&#!!!!#&%%%%!)++)&&%("(*))%&+%)"%'"*$+(#'#!$!'!**(+#'*&#*#)%&'(*&+')#*$(*"#"#$$'"!&'&+)%(!"#!#$#+$!(##'*&)%+%$!#&#(')"$%'""'##'&(()#&#'#'))"
@r707
ATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCG
+
?:)F9#.-B-#!'G9$1C3<<.<5.>)'=HG!E5%E.D@"?A!3.!BB=G%2
@r708
CAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCNTTTTCNGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATNATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTNTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGNGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTAGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGNGGCGCTCCGTGCCGCTGCTGNTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTNTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGNTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACNACGGACGCGTTACGCACCACCTCTTCCANCATCAGTTCAAGACGACGCAGCACCTCCGGCCTGGCATCATCCTCCGTCATNGCACAGAGAAAATCANTCAGC
+
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
@r709
CCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATTGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGTGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCA
+
A6D3*('1,-%$8)7B"3H(=D/%5B5-A-?'C9?75;&#!+,@.:E?-B7.F#9#%!HG)5@G4D?H4>3-A<'B*F6FG>B(-C0+CA0C63/=?'D5$49!!$B&84CG%$A9<"09'H/.8:+@0=47D/DD5.G$C,5<536@?)477:@9(/$#6H:CH2A?+!67A+*D%F52A%=->FAD!-C?%,$738,'69*>G(%)96)/7A-FE"$"3(7BH9%F+H">"0:%",<$G>4#<8&*H:H,'-81;3H4=4DGCA4=<A8$F8%:!"
@r710
ATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTANAATTGCGGAGACNTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCC
+
9$"01D$2>>4'&E436%94D&740=*:C-A*-?%.8'#0&'*<>0.D#.E=H<7"/<+A97DC"AA76(,&C;0G/?$0FF<4)FA-E&'<#:*(8)?5H'+D5752&*'=99!-@#74-CC%E&1'3@,6A-;83.42$H-$-5(/=/!?<$;,F1G#""9&?3BA:#7!.!#(90CFE0;-+'D;"!(=C:3#A463=</55.>EC."$1"<A(""/9<EFG=G);29:-H;/==15"E".:9C?7+@4E#02$8<979A+.1+?B7.4B@;27+:2E=-&@F=FC?FH4->;.H2.3:-FG?(5*B?1F;9%0.B;&!;33,>'(@=DFA44821G!5H(@?'9+$D!%?!"1'#:80$)$.'=)(FD(?0F2/5,1*EE7;BD&8DA#%58*:#/::#-
@r711
ACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCNGGTTTTTACGGAGTGGCGCCAGAGTGCCGCGATGAAACGGGTNTTGGCGGTATATGNAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGNCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGGGAGGGAAGTCATGAAAAAACTAACNTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTTGAAGTNTGTGTTTACCGCAGCATTAAAGCAGCNGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGGGGAGCTANTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAATTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGT
+
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
@r712
ACAAACCCGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCG
+
>$.B=CC(@#E<BA6-F=:C)E9F96>D2H9<G0B4A!A,'6@*1%""%3B;#'2*-?-D;%#EE*B5??*9EA*5E=";
@r713
TGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACC
+
2#A">'&).*4;*,(/81;;A>&0:F-"(41%*</:C)8C02?!H1C.13!6B$-'3#B/FG2"7==-=49/:;0*7@&+9D?@GEC
@r714
NTGATAAGTACATGGCGANTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCANTGGCTGAAATGGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCA
+
!(*$$&*$&+&(+$(%!*'*%!!#'%$!))$!###&%(%**)(!#*+&$)%+$"$&!$(!$%'&+(*$#""!'!('%"')%+"%&'%&!$()')#)+&!(%)#+(#%+$)+%'$*"#%&'$"$*#+!"&#*()($'+")
@r715
GACGATGATGCAGATAACCANAGCGGAGATAATCGCGGTGACTCTGGTCATACATCAATCTCTCTGACCGNTCCGCCCGCTTCTTTG
+
03!!H6+-3"(42;@=2D6.6,.9</?#!F53'*7D,*.1)G1?3B29/46H79,"?*1=G0>:2?8";48E;::2</?%;C9*/,D
@r716
TCNTGNTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGANTTGATGTACTGCGTGAATAGCGTTTTGCTNATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCNGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTNATCTTTTAACTCCNTATACCGCCAATACCCGTTTCATCGCGGCACTCTGTCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATNCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTNCTGCGATCTTCGCCAGAGCCTGTGCACNATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTACTTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTANGCGNATTGGCCCGCATGCTNTGATACAGGTAGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACA
+
+"!!*%!##%"!*!(("++''+*&'&+'%*)')+"$#!"$#()&'!$)&$%$)"%$(#&$!$)"$#)"!)!)$#!$*+$&(%*&)"$(('!%")$'"+%+)&%+&"!&+&%+$*+$"'#&*"'#$*(('""*!$%")%%()))%*!(!+("&*#!&$%"))((*)+#'&)$$*#+!+"('*$'"%"+!%(+&'*+'"!")"*'!(#'($&+!"#"(+%!%+'+&&'%+$++(#+$'#&%%'#)(')+'*)'%('+*%*)*"+"'%&*)'$!&'!)($"#)*(*"'%!')#*!'$'!+%""$!*($")!)'+!*$%!(&%*("+!$!"$&)(+((+&+!'%%!%++&+$#+$($%$)&#)&*(+!&$%&!)#&*((&*#()"'(%(')*)*+!!+!)$")"+$#$''$(&&!'&#$%!$+''%!%'*$)"%((#"&'!"(+"&%+)!+"(!#*$(!*&$"#&!%%)+!$**&!)*"!#'%&+$!&!"('%%)&'$((#'!"!**#)&'$#)#"!%!&)))"%"'$(+"++%+)%(++&+!##"#&+**$)*$'&*%($)+'&&&!*&$)%"!(%+%&"$$*%)*&**$+'&+%++*&)$)('("(#')$!$*("()*!')+*#!!*#%%!!&$(+)#&(#"#'+&!&"+$""*#*+(*&)+$&)+%)(#!+!'&'+%('+*&$+%"'&&'#$'(#%')*!"%(*('$*$!$%**$'!()!!'#"%!'$++'#%$$*%($'&+)($&&)*"$(#%%&)(!'!)!))"*!%*#+#""(("))+&'+$!#
@r717
TGGCTTATCAGAGCGTGGAAACGTNAATCACTNGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGNTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCNGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATAT
+
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
@r718
ANGGCCTCTTCCAGCCAGNACAGAAACATNTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGGATCCAGCTCACTCTC
+
.?/3A+%5;B?!4+2A::#!9<@60:@>!$@0<F)=$@H:/12CA;F7!@-3?>&C,:/-24,86=?D87.(HC!:@(!(9B9(6330--05(9,+(B">!;??#:.30@G(H5(#3H3C-.%D)"."H6;1*!('%(AD)#7?(!2H:3,7#3-@F/;;#;-H!8%ED"'0$"1F$GG9G.9*A=9+C</87/.6&;6)"G1:@%#".1H,*,9F$)14!*?D1>*D.C!*?;C-#$;E/?B**'0$+7F11B-+BE%:A>A;?C*8"33*&8A#45>.*@>A5-D1)')H,B!5-6B(8B=::?&/"&"G?"3!@C3277*;>-?5:>!-,95D,%(H$*5B)>'7$-'9>4CHD*1;,=/D.="G%8F"83DH75<=**C(H@$>&)A"F+2?!4<*;D>;0A#<(69G4
@r719
ATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCANCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGNTAATCTGGAACCGCGAACGAATCAGCANCTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGNTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTNCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTA
+
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
@r720
TCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAA
+
C3F"54HC3F;:7?8%3(0?@>2,9DF&#)C)4**5+C(F8
@r721
AATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATG
+
E>>;47$/55"<H/G$,D>!8$8C3G(!1B$=8C?+4G3&D7358$3#!;AC*9$>A2$%4FA!?D0C35F;CD
@r722
GGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATTATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTG
+
#'==11$#5:B.9<GA,E/89<9<048H,>0G:50HD5,49@,%0>.?(#GFF?*58"#&$*;B768.8+,H.'6.DH(2*&0A7"E7!9.":<7:H)$"?*D;<+H&+F?:EH6GD>:>BG4;,9'8?%"H3$*"78>3/-/"A"F;@.:'CH6C$<%2.EA?$<17C'.&#>1<(G+8",1C0;4F#%8G3.!(/1:6CBE"-:06"'/1,"<.5@0-?&":13%+F*.9@=?/5#32-;$!E'*"B-!?#$,H?)&@"<<$;/<$=6&#A@=
@r723
AAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTT
+
(7(?$$%(13GF-&&8//#;8./>/1=+3E4G'59"+-A6C%7#<$+A-AF'@75#3#;(/7<5+4@F2+;G'A:=B%8B(302DD@30"!3A&<C=:4"3&&);::#'.E03>+*>D*0<#':%F**@59(&'D
@r724
CAGCACCAAGGTGGTGGTGAACACGGTGGGCTTAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGNTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGAT
+
E74%.24!;B&0'.%?11?"+D,.E=+'A;&#$-C9&D&@;C:;9;"&09G&(5$8F?,5DB#*/?B?-<&(#D74:5<8@"A,B0/$(AH@7",AA?'8':#+697$;,<2''4"&$G0F.:!"%$4+1G"F99<(/"=E6-*"7(*00"B<5
@r725
CATCANCCTCGGACCGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATT
+
!*#)$$))'*"%!"!*%*(#+&%#'!(+!"&"!))'+$$!"(''&!%%*++*!&&)(
@r726
NTNACTAANTTTTNGNNGGAAAACGTNTGTAATAGAGAGTAACTTAAAAGCGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATAGGTTTTGAAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATAGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGANAGTCCGCACGTGTGTTAAATGGTTTGCCAGAATNGTCGGATTTCCACTCTTAATTTAATAGAAAAAGTACTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAANGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGACGATCNCCGCTTAGAATTCATTTCAGCATTNATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCGATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTNATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTAACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTNTACGAACATTAAG
+
!!*&))'#$*)&("*"%++$($'+%%")*&&$)#'#&"#"+(&'!&)'&&(')%*&"%#$&%*$$+)#&+$&%)#"++'+!#&*!&#%&)!$!&")$!)!$)'()"((*'%)#'+$+(%*(*%$*&$('*()"#$$%"$$(++!'+'%*'#%($#+('!)!&'&&")%)(!#+#*(%'"'!($(&#'$!+&)#)'*'(!$("#%!*(!#""+&(*$#%+(%%*(%'%&#+#!('"#'""&"!+)!%$!)''!%!))''#($+%$"*#&(%!+&(*%*'$%$&)$$'"+($%'%(&)%)&$*+(+#%)!'+%)$&&$*%*'*#)%)'$+*%+!#+"'!&(&'()%)&"+%+!*$!!"!$%+(&!#)*)!'"')&#&""$))(*+$$!&"+"*("$&*!'$"&$""*$"%!%#"*(%#++%(&)*"#+(#(*$*$$'()"*"+*#!"&%&#))*''*$&("&&(&&''%&)$&)(+*#(!'!(!!)""))(#&)&!('#*+"(%'**)*'*%#$$)**$))*!!)$)#*(%"&)#)"'+$$'"'"'(+))#!"&))""&)$'!'""%##"(%+$&!'($!!##)"#""'(*%&#'*##*#)&(*%"&)+#&'!#"!$%$"'$$*#&'$'#%"*+#&$*+%"&)"('&)"$%"(&"(")'%!)'!+)"$*)*&*'(!(*%%!)'!#)('+#%&*(''#(%$%#+")!#*%$&#""'+#)$)*!&$+")&&%!#*%+#")$%)+)&"*(#'#')!)$$$"$$#!+*'*''"$(%$'+%!$$#'+)##"'!"'(%+%%&!(*"!'"(%'&(&"!&!(&$""!)'$#)''&+*%'$&)*%$&&$#!%*#%#+*'!'!)&&##(&'""&&&(+###)*'&('+'#)*'!'("*+((#!+"&(+&$)!$#'!)$!*"#!&+$!*+!"!%!#($*#%(%#!'&"$(&(#)%&(*&+%++!!#"#!&(%&+$*+$)(%)")#$($+!&"(&$&#')'($%$#!'')&+%(')!'*"'##&"+"("""+)#+"%!!)!'#$#+%(#"'!#*+##+&%'"+(#!$%+!)!%$%($")))(+&#$*#%(#*)($+"'$""##"+%!+"""&)*(%"&'%##*'%$+&$"(*"!)*)!+$")'#%%*!&&+)%$*"'%$+!''%!)*$#"!%$(%%*+*%!!&(!#)+$)$$)$)#$#++!&("()%+""&"'"!'!%&%)&)$+("#%(*)+)%""##+)+!&(*+#)(**(''"!*!*%+&&%((&*(+#"*%!")!*#($'&)+&+'&#&'(+"&)!'($)""!)(!*&%)$!#)%(&'!!)$#++$$+$$("%"+%%#!
@r727
GTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCGGCAAGCGTTTCAGACGTGCTGNTCGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCNGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCNCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCNCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCNCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCNGCCTCTGACGCTTTCGTGGCCGCGGTGG
+
5F+/-?",!B9DA=5A4%!-H3;A'"&+%4%%,FG10G62.:&+17-?=!3G!,;(6.8E67/$'+C4+#9CF/A(H/@D82+"28B+/A<:/:9$:<GF"$?2@'E>H@@.;)';#+E-FG!'>@?4#E.@E=F:1FF<7C@13;5,"'<!E"C,3/+>1>%;@C!:3.%!;+.6653.A-3FH:+*5@)C?1D;FF#FF3/;''4D19F68!-<;3.-#&%!@*4H"6A9,6BCAE5@7C&;(7<.$,H9)>7%78%%/H=),6H<$0*@/!;E9*&"F"3$07>-2FF-5%*0!7F*G%!6H8-B&<0,7H?54B9905!-%"G>0,='?C,2*@:?=02-!'=D1.%.-D10'F;A;#865/5A72=@*CCG0=@B;GF9?H)>*&(,@*--=*D+9C%2$>1E!@<1&D1"@0'H0&:G;"/$8#5&-DH8.9>+%%?=%!EG#D4/"7!-%9..5D)01B'.3A,0"##!,#/%&)1</9-??>("*6A8076$8F3-'=)D#")G$'6(>'G-C=4@$9#)#,1.(+C03#!:
@r728
GGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCNGGCTGACCACAGACCCGACGTCGGGGCTGACNGCGATGGCTCGCCAGTTCCATAAAGTGTCGGNGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCANCGAAAGGGTTNGATGNCCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGNGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAG
+
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
@r729
CGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGANTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGCCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGATAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCNGCCTACANTGACGTCATAACCATGATTTCTGGTTTTCTG
+
?.B,56H->?+(?;=76)4FB5>?3F,D<969<@+??"939E7-!>B+.E?+(F;@8*E(3)H%BH%<8;-/,F:(=D:4/;A@.#'+C0&@B(3$1A.>7&EF-/4@BD;$(,H&E2A)587E31("C:D+(FA52,#+C9'=9?"(1A&>:<G20#9D*$$&(2%G$,5+52#?.H?#!$84*9E<"35-"/;@%?@'B?#2@,.AB<2GH@#D97('6@79-8=&7E2=!<%.C8G4&/3BG>%!D<9'(!B4+>*?=!)2*DH)*;'AH1D@:&6%F<B664F2':9%+=)>B6@0A,1,FG&32$F=2A2%2@F(:4ACF3%A6.H2'64)?+9#<//4(F$2@3B8--2%1,."CC&G<@2A=81758&8?=F%'>"3G-2H5/,BA;**#"?9,8$(3B;B1%"0))+)D@@''B)?-.+/7/$8?62.F661"G)6H:0
@r730
ATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTG
+
D$>G@->!F)<8@)9C/>?F!)"9*&/2?%%294D4,)D%8+:E80!"+3+
@r731
CTCGTCATAAACATCCCTTTCACTGGTGTGTTCAGCAAATCGTTAACGNCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGC
+
3,D0:;+C>G8;:0B6)/+04FB<B&7',5"),06(?ED)<<,,+.&3>BA>26G#&#+>%2D0G3-*&3.2CDD;'&3";@:5&#*"%48HG%-@)@'%7E%*F":,/!#)-
@r732
TCAGNCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGNCGCGACATTCGTGCATCGTCAGAACTAACACAGGCCGAAGCAGTAAAAGCTCTTGGAG
+
$*'#!%+"(%**(+'(%$!+)'!#"('#+%+(**+'!()(+&)+#'!%"$"#'))$"$'#%'$+%*''&"&#'*)#)!+))%"$$%"&*"!#!#++$$'"$!"(!*("+$')$$*&+**(#%%$#$"++!&!"++)"$"#%)*$&!#!!$$"&%)")+$$$($(%)!*'""#'%$*!#$&)%
@r733
ANTGTCAGCGGCAGGACAACGTATNCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGA
+
&"F&"2G")H(?*/+"5&D4BE5#H$!-=#322:'5A+1B#H!0.$%95?>3A*6$):G#""4C
@r734
GCGGCNAGNANCTNANAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTGAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGTCAATANGTGCAGAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGANACAACGAGAAAGGGGATAGTGCAGCTCAGNAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGAGGTTAAGNTGGTAATGGATCAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCNTGACTAACGCGCTTGCGGGTAAACATCCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAANAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGCTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGNGAGAATTCGGCCTTTCCGGC
+
()*"'$&$&#%"!!&!+&&(+"*#'%)$%$'#*'+'#'**&++#)*#&'""('+$!$&)$%++$()$'"'(#%+($&'+#%($(&""**)!%"("!"!%!#!!"&#)&)$$+%%'%#*)%&'+"*%""+++!*"""#"#'&&$(%&%#("*'+#%)'%)%+)(!*(*)%$")&#%*%#"#(*"+""!(*$(#!"&')+$(#)$#&)&**"&$(")+)'"'))&*('&+&)$#(*#!((++%!)&'')+##&&+'**&"!*&*%&)!&"'*&*&&%&"#'%*+$)")#!!&%$!'#'!'%!++)*!%%'!$!%*&($#*+')#(($)""')')$*$!$%""""+$('#'(&")('$'$*+#%!')'&%+)%!!)%+)$')()%%*$)##+%(*&#)')!#&+')""&)!$&%$!(#$##&%%(+"("$""%"!&%)*&+!$+#!%%"&+&("!(#"&#&##*)$+'++(!!%('$')('$')*'(())+$"'$%!($)!%(##"(%)+#+#$&%**((#+"%$&*)%$)%&#$"!$*%&!+*))*%"!%&!("+!"#%$'&#)('''+!""*$&)+)"&$&+)$(#'("!&&)#)"+)!$!!&+%+*%!)"*((+"#'($+"#%'!)#!&%'(%)*$(&"$+$($+!"+()%!#!*+)%#!+$$)!++$&&#'(*%%#%"''"%)*"!'"%(!))+)#)#"##%+'''+))!!&*''()+##%%''%+$#!+#!+"')+&!&&+#%+#$(*(*"')'&%#!'("+%#("&'!)'%*&'(
@r735
NNCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTTTTGANGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGANATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGGNCCTGTTTAGTTACGAGCGACATTGCTCCGTGTAGTCACTCGTNGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGACGTCGTTCGTATTGCCCATTTATNGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTC
+
##)+&&"%*''+(&$%+'*!##%'+''%(+$!'+!&"+)#$+))&'#"#"$%")!%+!*(%(!#)&'%$!*$*!#!%*)*!)%!"%""")!*$"*""+'(++*!'#$*$(%('&((+!!)!#%*#%("!%'#""#')$)'(+*!+##$$+"!%$"*)$')%"()#%))%(')%'%+&!+$'!!+"*'+))($)$"!)"(#'"&#&$()%)$*%*#'!%*+#&)#$(*#+&#"%'+&)$!##%&**$#(("%%#'#+**$))*$"'*+)%&#'##''"#+''$*+$$'''+*##'%)'!"*%%)(&&*&+"+)#'$!!*"+)*#(!"!%*)#*$'%))()+!(+&(+)++"&&)&+$(((%*%+##'$#!&!#!"%)#!%!+"+%!))&)+!!%'*(+(%#*%)++$!(*+$"$'#)((!+''%+'+)%%&)*&#*#&$'!%%*)!#&$'#%#))+"""'*!+"!)&+#$)"'+$&"$#)$'#""'$$*"(!#%*
@r736
ACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATNCGCTTCCCGAACGGCACGGGCGATGTGNTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCAGGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCGGCACGGTAACAGCGGCAACCGGTATGACCGTGACGCCTGCCAGCACCTCNGTGGTGAAAGGGCAGAGCACCACGCTGNCCGTGGCCTTCCNGCCGGAGGGCGTAAGCGACANGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCNTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTNATGGTGAGGTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTTATCCGGAGAGTCAGCGATGTTCCTGAAAACCGANTCATTTGGTGACCGTCACGCTTTCTGAACTGCCAGCCCTGCAGCGCATTGAGCATCTCGCCNTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGNAACNGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGNCGATGTCCCTGTGGCATAACCATCNGCAGAAGACGCAGACGCCGTCCNTGAATGAAGCCGTNAAAAAGATTGAGCAGNAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCANGCTGAAAACGTGGTGTACCGGCTNTCTGGTATGTATGAGTTTGTGGTGAATAATGCCACTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAANTGTTCGACGGTGAGCTGAGT
+
(+++!()')#*$"%%!%*$+$(%'((%!""**!(+%#$)''!(!$+*%'#*(*''*#+**+'((+!#((!''*+!!(+'%+)$%%''+$)+#'#&!#$+('"'*())()#&!!!&#!("')"%+"!%(#%#%+*$%%**$*&&%)*%$##)#+""+#+"&#"&"(%#+(!#$&*+($'!*$*&*%##)!'*!)#$"#*$"$)+($####$&')$#+%'#))&!)'+*"#*+)(&&+*!''#!%&)%)*$&$+*+$&&%")(&'$+$(!*##$*"!()$&&+"$&+'"*"(#!$'"#%"""$)*'*!&"'!((!!$$&()!$("$'$+'#"!!!+#+#('')##!")'(')"+'!'#*&$*$$%$#**&*(+!*#)"*+"$($(''"*+#)!!#*+*!"+'&&)%%+*&"**#!*#("$!&+#*$!#$'&+"(+$)""#'++%%$+$"'%&$&#*%%)(%#'(&)$)%'%#)##&+''+))**#(**%&!"))(+(#%*$&'!)'!'%%)"!$*$%"!""&)(&&#("'"")'#+%%*#'#")!%!%*$*("'(%%#!*&$%'!&$'()'#'"&$""$)*$#&*&*+%##"'%)#%$('$"!+))()+$'+!()!")*$!'%''###!(+%!(''%!!*%)!#$*&$!''''"(+$#((*!&*%&&"!!)%!!*%"&(&"(&#(''!')&"$$(%)#%#&#&('()'%)!'%&#"!&%")+'!!*)#()&"(!!+'!$"%+#(#%"$$%(*"($#&!*+&#!*#$"&"&#&*&*+$+)"&+''")#&$'&++'"#&%"*&*$$%+)&#+%#(&+*%#*("&+!''#!$"+)&'+"(!!"%)$"(())%%)"$!'(+$(""%##&'&(%!%&+%!+%**)*%++*('"%$%$)'('"+$((###!(!(&##'#")$+(!&)$+$)(!(($(#$)+"!**$&"##(!&$'&)$*'($)*)$##*)(!%$"*(*(&&$(!%%"(&)%('('"+!#&+!!!"*&!$
@r737
ATCAGNTNTGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTACTCTGAATGCTTCCAGAGACACCTTANGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGNACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGNTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGAATTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATNATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACNTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGANAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGCAGTTTT
+
%)'))%()+%$+$")*!!+$%$&+#!!"$)*(+&(%"&#!"(&'$")!(#&)+!%%$$#+%$"*#&(+("%!$#!$)$)&*&$*!!'$%$)*'(!*$!%#&(&($!!&"(!)#+'$$"++%$!&!&)'+$'''*"&#%'%#'%(!'('&$%#%+&*+*"(&&'!)+!*&&%+'+'!"#&&+$$&)!+#&!)()"'$$*#+()+&""&+&"$$&''$&$+*'!'&$%)'*(!(*!!*$)%()&)&+""%+#)')+)&")*+(%++'*%()''#%"%""#)%&&('#)&&*%!')&((*+)&$")"+$+$&*#$#'+*#%)+#%+#+#'#'%'#%&(%(&+$%*!*)%%(&*$+$*%!")$%'*($)+!##*%$%)#&+""'+&&*$'))+%*")+'!%("('&+(!&)&*"(*%(&$#)))#&'%*()"#%'"$!("&!"&")#(+"$++!*)'("*+$$+%$*"%)"'((**+&!&'$$!*"&&+$*&'%"*#+)!+#$!&'&'#!%$+#"+$*$&*%%*'$'#"'(*#*$!%%)&)$$!"!**")'*)")(!))*('"%!+&!!+&"+!'#)&!"&"'#*)#)!$%*"%"""$&+!#*&")*($"''#%"&!"%#*("*'+)##%$!)+''+)*#''+*"*%""+'&*&**+%!!#'#$(+!('*)&"!"')("$*!"#'$*'%$$&)"*!!%##)''&$('&!&('$*)(+$!$%##*#"!+*&(#!*$+!"!*(%''(&&+#))'###%!$!#'%''%#'!"!%($')'&##)$&!'$"'&*$!!+%'()$+)')(&%")*&#&(
@r738
GTCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTT
+
!"4E5,9':E7*3,B;+*;39E-?$)8&+=??D/+B?<F7.=ADG@''5+$@B=-B()1(A
@r739
ATGNCGNGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGNCGCTA
+
%*$"("!+*('(&+!)*)&'#&*($+&%"%!&)*')($#%+)"'#"%)'")(($&(
@r740
TCAGCNGTCGCGNTTGAGGATGCGGACACAAAGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCGTGCTGCAACGCC
+
.$1,$4)!*%:;+B-D):(*+?D$H?$))879//AG@BDF4,B17FAD>&1,'9<(>9?>65,<<6D.5%4(F<C*?#0*F0"'4*C1<@0(C4<;('
@r741
CTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAATTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCNGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCNAGTGCTATCTTGGTTCCACACTCTGGAAAGCACCACCACTGANTAGCGAATGCAGGGTGAANCCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTCGCGCACGTTAAAGCTCGCTCGACGCTTTCTTNTTCGTAACTTCGATGTTNGTCAATCNCCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCACACAGGTGAGCCGTGTAGTTGAAGGNTTTTACGTCAGATTCTTTTGGGATTG
+
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
@r742
NGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCGCCCAATTTGAGGGATGTTTGATCCCTCGTTTTAGGGGNTTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCNCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCNGAATGGCAAGCAGCACTTTAAACTGTCGCTTNGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACNATCATCGAGATCTGCCACATTA
+
&<?'5;CB@,,01';D)&#''!.D=<F2,486#%'0#((@E/5/2$:@0%>!%8>:E9(+=&-'F-*1!1F#,6=*>D1=:@%,6FCD0AAG%;1=+;&.8*2:&C#,C-D>C388?B@.7E"D+:(7F/C8H6<D2C4H53#F)53"D8F4)-710"0;.:!*+GA?12E%F2B@;H:5F&7,:,*/!ED:6*3@=HB!34=.&"+4*./A!:9"1H*$F=,&-.7&BF?;FF9#E!+!E(B"G6/=-<G+!+B#17'%&.<;/'B"3-.#0/#E0E&?H../&=2E>:*)((796A7.=C';<>$4$+"/:+?#D@:&:&(D7:>F#19<:,*=2/@;5>;G5!9'4C"?';GD';'B@C>7D/E("6%"";?208111!182.>00B6>:#C82'#,4)9A'8$6F:)G+)3#D;*#7.H?4/D4E#?.+";?14!@"$&9-6
@r743
GATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAANGGCAGCCAGCNACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCNTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATNTCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGNCCATCCTTCCATCATNC
+
6C,'(#:94A,2@26A)BF0?+1D*9-0"&;8+.$A51<&=$D33@?C#:%C2AF"7%G21-#.A8=?'0#<BF-0,7#=5;-+@=3;45&&=0?*,D.,;>%#!$-(4'DAB!7%2F=9'%%:%;C/<?=9H:'D9CE@3D,C/H4(.322C*D+@,!2CEC!.'FG@=+'%5H9CD$)G1E<4.C4E490@74*+"8(3*C6(1)>2&8BA+;#0"$6C-B=DDA%15=><*1,?F75@@32&CBHG/:AA%!=:4>995F9G1-$C#8BG:@)H8#+4G2<>+H()'9'5&0:0
@r744
ATTTACTGAGAGCATTCAGATCACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTNCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCG
+
3.:AH3C$*2C."2<1H%$#(A.7<E;#%6FF@10"&!;/=3@C,9(;8;&/,:(88%+/A,B><;"D(<A@%8C*)@/'A(31%>60&G:.0"1@50,H8.+&.'-2G0%+&G#18E4(%DA!/%$<<E')$(+"B<2FD:!<F0A>3.A6'@+0C)4-.G;@0;&45-
@r745
GACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCANCCGNTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACAT
+
-?.410+GF!E8E8F='9!)?::,2*:FF@5E7(E>.E9,2=*A7-5&,/0,+FE<GE<47@(+6&@0@3C<E9C5$%$AHG%#D@&HB2<:H,<==)B=-$(E+0./>,G$$0@C'""3=0HH,6(4"'6$@4<2;)H04
@r746
TTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAG
+
%77GB$"C.C(2#D3.3'';-HE6B9!!?=,)6&0-24,66H":34&%*13;
@r747
CGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCANCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGNCATGAACAAAGCAGCN
+
/#*$=B>C+.)=->C5(G&G>A$8."3E%?2'#+;9%?A96B)HC)80+F+!)1/%?,HG6<%$5;0)A:?)43&"?./AF(<6<"0+";$@#"D*#((8<;9/:F,'&&93"</61)59*3A!@!#/)'@)$'(<6A#+?BB*1>>))B-:86!!8/D2<4,@$$*4DB>=.8G=&>D-)A+<?;6-?2*1+2@@&%)195:2,!"H&1'&<8B8*/.8>'3)D%5CF58F('D<CDE'>9.&CEF().!3$5GD,AF$5H:GB(-,B-*+D..(D0;(C6'"8BG2,E0GE&"+,@C202<G$431:,,HHG(,58G5+<::@=AC%G4>9,-8%HH@D+A&C;HF%G5D17+78?
@r748
AGCATCCGCAGGATGTGATGGAACAATAGCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGANGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAANTAAACAGGAGCCGACTTGTTCTGATTATTGGNAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAG
+
;73*94;DA*?,HBD"3=790;0/>(G7-/407)F;5+=,1EB#3)?"$;'9;2>05=FD/AC5BFH=''F.6(:E"A"(3;8>F=6H%30EGH$:!-"7)&FH%09.4-,@(A75$22)E2<CE<!)H<==24F/.%$$>?-*@3(F#H6G##HF%HD;1F&FD"'$6A"B*C":A'0@.?4"=4=.:G#2-7.D>8F7C,5'##@?0.!D!D1-EG0=E;'7>0<5GC+@686(%?5'DFG?+%59DH>6!/3A<C/156!<&!%,=1::.;EB.B=6E3/$@G'1GDBG+'@00'/?2@?G@+A1?"'(5:B%2@?!/%+(>@*B@.=63CAA5/1"0<-C4.!.>,'8BG-=/4)'&%78E*)#'/(6-C*3"9"4=7"2EF4)4G)B5C=;BE9.:A5:D-1$??0%"0B"!DF"*9;(+@(8-;0;#H%$9F<#EFB,A(')-.#/=D=F<A,DEEA>1A
@r749
ANTGCGNNGNTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTCTGTTTTACAGTATTATGNAGTCTGTTTTTTATGCAAAATCTAATTTAATATATNGATATTTATATCAT
+
%$(#$#''$$"+"%$#(++%(#$$&#)(&!%'#%"('$)+!!&#&$%%!#!*'%+()(!!$%!'&##($%#%'&)+%$'+*')+)&%!&))#%+'+)$*&#&'!$"&(+)&")$)('&#+++''&"*)(%)
@r750
TGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAAT
+
>7&'1:)3E)3%,4'#E@2%D5E6FF?F7G=1>D?&9=C'.$!CBEE/87((*1&&'+BE@F8=9B*<7$3@4#(2/*H+3F,-"A>F6859/0?E1"793F$@7/>10+(+@6>@'%+A.E2C#8H,(4B.=.72'0D'@A97((,:4B@&@E(F"<E,/#":536FAD"#*;@@E30'&4)E*33/7462);9;F;)!*&/:-*;,B?8)2?/E2+-+96-90A0(C/>+/7A<<)'/71"EG2F/;H!9@1>EAC)-
@r751
GTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCGAGCCGCNGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCACCATTGCTCCCCAAATACAA
+
9)66CCE?6$:)@3$.4810+?GA/<B(5(AAF)"96:D:.CH;G/A?AF*90$2#4/:H10B/@>DG=4-8D(FG';"B5>:-9)'<C=65!*E(=GGG7)1E6D!'$,E*/-)<$,562DDB=6CFB4B"4#3?85D9&82?0*<>0!67372?@8C=9&:9>H;"5%+'D8$9>DE)#5".1F*?4!53C,-E-;<#FF2>$-<G-+84-@$2(1D90.74#6#-(+&6D:C0'D?6;%,4B9'<4+@9H+)B#&";(!:2:'180C0A=+&79.>))E/682*6"6",>9F$@";()"-AG'?:'>60179'.&;%?BD>835+"?E.676?*;CH5C&1H!5285$7*/22/;*0
@r752
AATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCACAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTGAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGNGTGAGCACTGCTGCGCAGAACTGATGAGCGACCGAATAGCTCGATGCACGAGGAATAAGATGATGGCNAAACCAGCGCGAAGACGATGTAAAAACGATG
+
6&!>C5G&!8<HF3EF'C57#,7$GD3!>#?EC7&8CG<3.@'03-+0&)87=6<A.C>A>$G;,3A&/-G($1,.>CG7G-G>:-#G62C=8H!90E$#,A/<:/-+%?5ED2G&>9)@2E/@%?3B2<&>3&%1):@"-'"7('6"D;(<.1.,*E3/'4)8?(%48)@/GFA->):##E-H+(.@/A7-6*,,@B!F./'>)0<(@+:4%964&BA6=88D+@=%6*;:82A1:*,"84G#?&*%+8:8:66<'587+(5A$5GA0C#9.5<#'.-."CE"'/:?-/*@0D0-DF/?@.#>#>5>;D?3F8H)*D)"*F%.;B02/=57E-8H<"6$'AB"1CB?)2!-4A'F/!?6=3B6>>84G'.#9<,E140@/H$C:#2/C/0'H9!8,;E!C+(F*%10>;5!-:$47"$/H5DH4G!(+6)08%),C%+*F>@<1"6&"
@r753
GAGCCACGGATGGACTTTGGCCNGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATNCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGNTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAA
+
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
@r754
AACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATG
+
<E&-&H+(5,,D/2>A9'>7<D:)9()=:H1HFH5=$=37H+D('?0B79%-
@r755
TCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTGGTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGNTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACA
+
0G+!1*312&F*CC:@$H;)2,E;-8.>;&;6D-*9=3#2!/93H2&*54%)&/E'A@6,F&/67D"0.D;>45@H$67$7=DA!1$F8+<B"8/=D$%D$0.A96?!+,%-B,G!DH):)C,@1G+31&!A""2$&(+/@!%E0A/,;8:6<1?#!?EE:":,@C::=-)8=E-=HG3)7<:G87&&E(,?A36.6B4E5*F0;61@/?>7:)1,+DH/8"C&8&1/,1E4(>21@B98=;;E/'!D?EB",37/A!1-!@!H;%C5?EAC0;$A;<$:7'("&3)=B'>:93<B)A''A)=D;.?'G$@8E:>(#21G(2-A%0@/#'"3"@/E8C27:8%&,D+#87#!?9*B9A"8>:E.8;B=1EC;5A3'-:=:8H&-%7>(.)-5A,-(%/0-3>;+=!F>:$"
@r756
CTNGCATNTATCNNGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCNAAGGNAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGTGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGANTGTCGCCAGAGTGCCGCGATGAAACGGGTATTNGCGGTATATGGAGTTAA
+
$'&*(*)$"#%%"")")+((&&##!"&!%#"'&)+()"#%##)))(#&"#%'$&')*+*($$*"'*+"$$(%##"!#)"$*&$('##%(%%+'($(*"#"!'&$)$"($%"#'&$+%+!&&")#(*!%'%!(*(+')$$#*%(++'"+((%#&%*"*%!('##&'&$)+'(%($'*+#%&!"%*!(&'$'&+)
@r757
NANNGNNTNNGTGNTGCTNNNTCNNNTCAATCCTNNCCNNATNNCTACCANNGNTAGCNNNNCNNNNCNNNNCNCNNTNCGNCAAGNGTNAANCTNNGTATAGNCCTNNNCGNCCNNNNCNCNNNGGNNTNANNGACNNGGNNGNTNCNNTNNNGNCNTNNGNGANGNAANGNCANCNACNTNNNCANANNCNTTNAGAAGNNTTCACNNNGGNNTATTNNNTNCTTTAANNCNGNNTNGNNGAGGAACCNTTGANNNACNNNNTNNNCTNNNNGNNGNNCAGCNNGNCNNNCATTNTGNAG
+
#!#"!!!""!"$!#$$"#"""!#$!#$!##"$#$$##$$"""#!"$#$$#$"""$$"#!"!!"!!$!""#!$!!"!!"$$###"!#$#"!$"###$"""$$!$!$"$!$"$!!!$!#!"#$#!"!"!""#""!##$$!$$!##"#$!""#"!"!!!#$"#$$"$"$$!#$!!"#$"####!$!!!"$""$!$#$$!#$!!$#$!#$$#""!!####!"$!#"!!#$#$##$$#$###"#!####"#"$$$!"$#!"!!$#!!!!!!$#"!"#!"$$#$$$$$"$!""!"#$!"!""$$!!#!
@r758
GCTGTCGCGGATGAATANGACCAGCCAACGTCCGATATCACGAAGGATGAATGCAGNAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGNCTTCCTTTCCATTAACAAACTTCCGNAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCCCGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTGCACAGCNACCCCGGNGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATNTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCNTAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCNTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTNTATCAG
+
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
@r759
ATGGCCCGCAAGGGTGCCCGTGACGNAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGAGGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGTTACTGGAGTCGTTTCTGGAAGAGCACGG
+
=41331<@4</?&>>19!@H,!&H<5HF&01,'!<!G,-$&14F/B?5%989F0#215/-(6C,'"*&,9)&<>&,8)<>F!AF08=$;8,CE0C</&C$G+(?@A'1'$C;+8G*'19'#=#"5A6>8C/78*<()+7/+!@=@1-G%%&6#?7:!BE$?-.)E76)(780?;;/.'>A8BAG.G2D9F+DG,:58'?!-=,.)EB+'6<@=!-2!#;-6?(D),/E3'%>F!!$.$51>BC.)8&48>;A*0;E+>A.A!A!%,:7>6-
@r760
TGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATNAGNAAATATAGTTCAACCGCAACGTTTCAGCAGATACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTNGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGNTCTAGAATATGATGANAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTT
+
+%"$"%&")(**%''('(*("!+%+*#*"!+()+#"!&*$&&#(!(+()*'"#&+%)+#))%#&#+#%&!)%!%+(%*%&%%!+%&(+'+$)+#("%!+&!$)(!)$%#!((('$"++#")%*(%%""+$&'++*#*&))('&!#))+$!$"%"((*&()"*+!!!+)+)&#$!)$''!)%+"+&)%#%((*(%'*"+!+()!*(!+*+$')$*+$$%%'(($)+$%)&$)+*+'$(*%+")!)+!'*%(&")
@r761
ATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATNCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGNAGATCTGACCAAGCGANAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAANGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCANCCCTCAAAACGAGNGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTGGCGAATCCTCTGACCAGCC
+
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
@r762
AGCCNTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGNAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACC
+
;57/G%B.(BDD).06G7::6:D+?#B,$0(=+..%0*;D/?(B+64>#HDA'7@!(-'.42'3G(0:#H+#1"#<0(DA5%'"028.'/6+994F'G,AAB4?=56.%C!'F;/(/<((F03"5CE156.>,7<CAE15H)H3>?E=)*18'."EBE9)%/HDF5=%#5F,=+/<7;*B%E@+;4("6G78';/66=:!(40A&@9>3<"-B3B:2$G7&@?0F%6D:1D9%?>D$E65<6*F>3#CB06@4):7!#F*8.<,2=0A'H4FC@18-*!'$#'A+%5=0$5D(,<5/+$#"8;#/9)%E)-3&'6-CB,)*1F(-4>5'A6&":B.:>'
@r763
AAATACGGTAATTTATTTTTCGCCGGGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCG
+
-'*A9915.=C$';48H):B<E@A2@BFGH64B&:-$B#G9EA$'?25(H<7E3%+!,7&+A7G3)#*)B<-?(;GDBD;,/9<@>!-.E=)(:;,97A157&!'1(3;=2+(+&>3">('D*B68,&%=1-3$(CE;.-;-%,8<G0@>=A<9-3
@r764
NTTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCTACATCCGCTTTCCTAACCAAATGATTGAACNAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAAC
+
"5/=5)>:)G21=90-;.%-71!$*?<45>5)#A=FF3'G/93BBCB65@+3$86%'850<7*F*$8?'46;>'0H0@AG62%>%542'9+-;D7E?)#7E"5='B65428#+$$5:&:(D-,89DB52<2(5!FCB@)-<D@>(8F#C#6?.E482@7FD?$DB<3$>0/F;*D2=H9F-DGB81=1-)67,<!(E,:<69B%;(G497A2B-:2)A.#F7=(EB@2
@r765
CGGTAGTAAAGATTNTGCCTGTCTTTTANCCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGANTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTNGCAATTAATGTGCATCGATTATCAGCTATGGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTT
+
62-#,F:#8(BF4>FEH)D*.!4=5;@*A=+D8:*EFD1$F45'&(G@63)F@@G-C<30A*2%$&H"<5B(AED9//0.6G2$--8>//"?CG-"')(58(=6$6AC<8$3!5.&@G9>,20C-+#+@.>1()*+/?+C=><9),F*4*1#B7<5@#B854//1.%;1%/'?3(:&35+6C%E4H#8$1)D8"@)F<#@F?2#D5C""59,*!9!6BE!F2B,+>E/)$)0=$G<A),A"!H<%?B(>1D;G6A5:,3E&#>.G16F/@=B;*=:F8<E##4A(G11)'H7$D:#857.!!=15'./41BF:B70C?0D2!F.A83?&*&H6>C<A.!=$.3EE!'9%?8<C%*#>@.8C+5#H8D)$(?1("C2
@r766
ANGGANNNAGTACAGCAAATCCCANACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTA
+
("!"&!%*#+$'$&""&)*!+%!#&*&""&)+*!!$)'$)*+&#$(&+"#!&##(%%(!'$+$((&&(#'+%%*'
@r767
CGTGGCAATCATGNTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCTCCACCAGAGCGTCATACAGC
+
#950;BF;:$5)'-5F5-@,0:+58&)=?0GB6F;A(%>D2+&&!';A2A..<-@".D;CF$.*0+CA4:)%&D&H&:!'1.>;4&5G6/AH7A&
@r768
TTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACATCCGGAGCCACACCGGTGCAA
+
*E0*;%?HEA#G"$(-D5;C?F/'12B8E?@H"8+'C2+*,"$06%9+)"9*D22#..-D#C%#E80*=.5#.!73G!<&92&!-
@r769
AGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGNTAATGGCGCACATCGTTGNGTCGATTACTGTTTTTGTCAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCC
+
<*6(,3+FE2(85<;-&C*$(>FE3<&@:A986CF:H*;3(3/1HAA1A.;@&"@G9?+>E,&.<H4B6=!+,'#4>CD&/D1-5)+(DC83&)5.+%F;+FH51-@.+@.6;3':#:A*C+,&9:1&F3A5&'*'A.A)/!8C*@1,$1H,C602"-+8$55<,905AC'"2D%-/5=3,$2<*+?-?95%'<$/?'@#,6;H1'5+F(BAF7?54B%+&;/2%%6&A<$%@%+;"F
@r770
CNGANACNCGGNTGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGCACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCNNCTTTTTT
+
"%&##*%!%*(''++&)+%*'&'!$)*(!"!#'&#)%%+$"!)%'!+#'!*)+!'!&$'")'%$')!#*(#%&#(%!#+#(("!!$')*$#'''#)#(+'%%"&"**'($%()%'"&%%%"'%)''%*'(%#
@r771
GCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATG
+
>>+*D9F.<7'-3E4+!=6H3+?4*,.1B70935>.0A87G(7F*2H8!%>G,6(6&1F+
@r772
TCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCAC
+
31H/*CB=;.1&9?0#1E<*=GB(36,&$3+:-7./=+-@H=$18?88(%+25G*2?#@'5(F(-"!D*!1
@r773
TAATAAAGCGATGAAACATACNGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCNTGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGANTACNCGGGCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGA
+
73/<!(3*6*:>*(<5:G@4B1=&?$'HE&@/18"!AH+,7D3#5&,,5)9%&-E19D/CC/@$C)74HE=C7A,8.>'$H:/=#8.-.A8$,/**.&E"0<!4;:/*7F)E4;/:"5B+86F(=1/&4G7%2F,/16)%)B;"2)("75E!FG=?<'6=AFD=(<(0526<>2AA6;+@%&,%?>B1$88<=;G"BF=,1("5G@64,=8C$06?,.<5$*%%09/E
@r774
AGAACTTCCATTATTCTCCTGAANACAATAATCGCCAAAGAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTNCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTNAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCANCAACGAGGTCTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTNGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTGCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGCACCGANTTCAGAAATNAATAACGCGTCGCCGGAAGCCACGTCATAGATGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAANATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCTCCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAA
+
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
@r775
TACCGACGCCGGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCG
+
<?29/<DG,<$ED.F%B490-..)BA,11=>F8+(1(*B<:%43G=(&27:8:H*$58$#)/$G-5E/4-/5)-@G?=1"@$<C%6+)4()07!,7;0'BF.9)B(&@E6#"?$785/C<H
@r776
CAAAGTTGTCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTATCTGCGCCTTTTCGTCGTACTGTTCCGGCAT
+
!?;?@$=4&6/4<F?1,9&3,06-6:45*H-E64F8(@,8C>+H9>#4H0F-==1!BG$0!?G1:<32)9-:3!%'CDG.+(%.C1+
@r777
CCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGNGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCG
+
?&/)5B8',4#G8?#B8?A.7E052*-%4%=.0;8/2,.7D.(G7!9A#0BB.B+"*:%F8;<F*5*A%C$A@CE$)%H35*6H2'4)">7@3)G3&?CA(>2D#.GEAD,>3HB.;,5"8)B!/&B+D/4/.>,H3$08#4.E/E$H&=@F=6G<?.#F$"3/#%#$A1.&
@r778
TTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGNGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTNCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAANGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACTGTTTCGGTTTATATCTNNACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTGGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCTGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGANCA
+
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
@r779
CANCNAACCGNACAGTGCGGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACNGNTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTNTCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACNGCCATCGGGATTTTCACCATATCAATGGGGTAACGGTTTTTCCCAGNCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAAC
+
"'#)!"#$))')"%)*()$+*")""$'*'#%*&#'#%&&&))*)+('"%##&%'$#+""$!!"*$!!&*)$))&(()&"%)#%+&"#$+!(&!$&+(+$!#")')!#*'*!)'$+$)**(!&&*%++*"'$&'*$$%#(#"+'"($#&""'%"($!$+%$+'%")$&+"'++*$(+*+#''(+%#($&*#%))'("*!&$)$%+)"#%&*%*#)&%!'$++%+&+*($(*!*#**&###)(&#+&&!"'%(+#!+&()#(%'(%!!#*#+%)!#(+$*#!&#$)"'##)*&($(&(!'#*""#"$+%"'#%&!*(!('(%(*%&$"*'!*$'%&!$!)+&*#!!#!%!$&$'#(+"#*()&'+++"$##$(#+*(*$*&*''+&'&%'!#!&(*+$$!&$""%((+'*("(+)!*'"#"!$'(&'+*("#+)!$$%'#)'#*'%*#""('+$*"%#%!+"*++(+#)*!"&*+"+$(*$&)$(&"''+%%!*%$'%!)#)'
@r780
AGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGNGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGNCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAANGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGNCATGCCAGCGGGACGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGC
+
%:8%%59>7B"%&C.5G")'9!3$&/:4((;)-!/+<!<1FB(C'1%)"5A1A"40G!!%32!(C,)$9AEA6A:;-<FA2'?!5GB?@&*962;&-2>??$#-,G=?7'<=G))14/H2$F12G;-4!/*-53$*341@7GF5*)%=12*&E5/"/C4#EH@E%C0#-)GA97!E>#%$D+(*/6!*5+::'DG&(=8"4'G+C090"A%?1.:9'+2.2"#4F=7%,:?CF3?&:8F70.2:=(06D+@D(#=)GC$81/A;158H:;/:%@:9+.07#,=8@"63"/';429%3/C">3
@r781
GCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATCGGTGACTTTCACCGTGCGGTTGATCACTTCCTTCGCCGTCACNGCCTTACCGATACTGCTGNCCCAGNCACCGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATT
+
#F1586:7@F,B=3=9#7$3$=7GF,E6A'(G<1"?B:*E/@$>$"!"=A7:3-G?0;D?+!/.B3(H"D&2<84HA=>4H<($4',67!)C)B1#"/GD4,B.E!15A4&+-2;@+=%9A8G$"=;0,H@(:)C!$1C$!0&<==;BG8F/D:!DE=#:<A:(?G'(9A9C2F<39.B76!3"7.*?-)0FG74@1=:>FE<6:D,B6G'2,,F2)A88?-08%GG+5'0+
@r782
GAGTCAGTTCAGTCAGGCTGGCGGGATCATTTGCCGCAAAATACGATAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGAGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAG
+
#4-!H.%623('!#!/G05GF>7+E0$&C?G1114=/,CBH!!D!E!4(.1+(*=8;AH>C8C!#F?H7F1,=>C7D!74E?(H81:3?-%&.,*+G;!-370D46%+7>1C"9<"2C9!?)G?07?272.55;>5F7.D/!5#C211$(@'-0E2'64F<5C,/+(#-F!#:B87=@4;7')..5B8>+<8)H+%0=
@r783
CACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGNGGCTCACGGACGCGAAGAACAGGCACGCNTGNTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCTCCACAGANTGCACAGGCGCGCAGTGACACTGCGCTGGATNGTCTNATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAA
+
EG?H-9>H/'%$BH%!F.!443H)03%=2(3.6E+('$!@7BD)A2@)1=7@)=1.C1B11H460&A+7%0F#FA%&,0,"&:(+77-7<F?$=#=!;GCH?*5&G:D15E@-$D(?GEH1=2:;7,;D?49);+++?.H>/=F6%$0.*C<<@.77;%F.2;!-#7*;F*9%0(,*6=B.:%"EC5<3H>?-$B:6C('H0-6A0152$/*>#<#A">@C?&@8;++32'/48@(A-)=B9(+"AH%+>?2E<#,=BH570!<$F#$5)C!BD+477)E2'8D<A3E93G,,<DF*9$1)C668#A47&=/7G3-1*$/>2,<=-E&3?9"G='<>:-:'9$6(D,F='<##;>@0"./;',9.."=.G?%>,%6#:@).#1(2-
@r784
TTGGTTGCGNAACAAAGTGCGGTCCTGCTNGCATTCTGGANGGGAATACAAACGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACNGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACC
+
-5110@.E-28#9,2GG>.HCC*;G$7'),+)6=B=($21*>C58/5C;5DFG(BE,<+"3+3B>?'?54">.(H'<EG-(?2F&=.6';84H7"B*;A?)#$:""9'@!"5GH;';BGD34:HFD:&*+?AC5#32D8,0C*("!G;E6EB;H9)$%-(!++=(6C0<>D$:=B9;H,,+&"$@2:7<B%/!A;:C>1,,<',!4DB%).6)2(F<)EG/6695
@r785
AGGAAACATTTCTTCAGGCNTAACCATGCATTCCGATTGCANCTTGCATCCATTGCATCGCTNGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCNTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTNTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGNAATGGATCC
+
G=#>#;6,A/(GGD57:>!&#>BGC>G<(6!/',CD&GA%+=:===C>.0.*#@&,A=G-+.%HG8&4#$B7'E-&9*2)1--C-H:<6GA2)F!:AC&A%D.<CCH'$C!F3)9'>AG:%%%1;1)@19E/"<>7D$$<4"'H@8@A00+-%>1-4%+E*,7&!2.?%%<4%#(/)5+E4@'**'9!&2";=:HF<2(6'>0F5;>%AG?/!&5G+G((1.A:@F,)1BB:F*G$D*65->'G+=,564:A//B9&EH);<6",<?+EEAH0#EF/D-@>6B>*$67BAE5(6<BFD'!829>:8:22H.H'-=:.%1!9D
@r786
TAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAANC
+
*/F,/-3,B*98=45725=-)8G6"=2BD#"9H*;&=/%4E,0!<?)87@=0.F0:2-2,=;,+2'A1,%,CF$2(9<<!#6A-<,)<)?/0EA0+0G,@.!(E')>F/D=(;:'@/<2'3;B?<?513E=A?A6+B$;900</;#,"/,"+3$B9G21#74@%D=6<'$F.0.'B>DD>)"$368G%.G(C"3H=A"2((=<5>!%H?+(#+>DFB)0?)1+9%*0,G;(E>5(//C.5;8D$;.,3>B:B7+57=7E91:7&*(BH1!A05709$!D#*?=56%6>54CH.%:@C,9,+B$.A4B)!!<)@%(.C$7AA;5D'%
@r787
ANTCGANCTGNNGGATCATAACGCCAGGGAANNGGAGGAGTTTTNGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTAGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTAAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGGAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCANCCAGATATTCATGAACGACGTGTNCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGC
+
$!(*(%#**&!&)()!%'&(&%*$)&)!*%)!#+""(&#+*$'"&+*!""#++'"+)$**)))$")(($$#(%"((%((!)+''"+!('%$!&("+!$(#*&%%$("$&#&&$+")$)"+('*"*+!)!"&!+$'#%*''($)')#"&'$+$'(''+$)')&!!")%"+%&#)#+&!'!"*#&"%"*$!*((&#%$#*""+'*"%"*(++*''+(!"$'(%%$$*%*("#!#&*&#(($**)#($%$&&$!*&*&#%+%!*$""#'"&%!+%'%#!$)%!*#")"$!%&#%"!+"%*((%&*%*%()($'!"#$*&*###*"()&#%!%%+"+"&)
@r788
TCTGCATAGCCAGACTTGGGGGTGANGAGTTTACCTTCAAGAAACTGATCAGGGATAACGGTCAGGTGTTTTTACAACCACTAAACCCACANTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCTGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTNACTCCCCTCAGAACATAACCTAGTAAATGGATTGATTTATGAAGAATGGTTTTTATGCGACTTACCGCNGCAAAAATNAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGATGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACATTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTNTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGNTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGAGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGNGCAACAGATATTGAAGGGGAGCTNTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCANCTCGATTTTNAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGTCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGNTGAAGAGATGGCANATTGCTACGCAAGAACGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTAGGTTATCGTAAGCATTTGCTATNTCCTTTTCCGCNACTACATTCTTNGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAAC
+
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
@r789
TAATGNTGTGTTTAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCNTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTG
+
$((()%!+*!!$!+%&'"(%"))#('#("&!(&'!(#!("'"(&&"+&)%%(%)'%**()+'"!%$!$%(%'("#$'%&$&"("!"#)#"*&%)'!#$""%&&!'++&!*&+#)'"+#"$'#!)'!'$%*&')&##!!+''(%#!('*#&**!)'*"#*+)(
@r790
CCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGATNGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTGGC
+
)7F9$G=(5@*;E=.AB"HE324*59%>.BE/@G6:+4)G*FC*F>>5=*:<7GHD=@39%"D)EGF<?E:#8#)AA>?0++,9"(:/9@/$=@-:(-!EA-!.!!11A-=44CH&;D.3%*#&EHA:%AH86'-E>!?.''#
@r791
CATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTANAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTNCGTTTCATCCATTACCACCTTAACCNCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACNTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCNTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTNCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCT
+
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
@r792
GATGAACCGCTTCCCGGTNCCGTTGACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGGAAANTGGGTGGATGGCA
+
F.:A??7='1'/9&/F8%+CF2*&$C=B@G3?.H&6:@7='<;9A."7832D!G&D-7G:BAB..%=0%4E,'!().?9<(*8>F#%)?=C&:'8+A:+A%"E1FB3A#?1D
@r793
TGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATANCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCCGCTTCCTTTCCATTAACNAACTTNCGCAGTAAATCCCATGACTAAGACAGAATNAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAANGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCTGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTNTGCCGCATCTCACCGGGCGGCGNTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCNTCTGGCGGGCATTGAGATGCCGGACNTTCATCGTGNGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCG
+
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
@r794
GAGTCTGGTTCAGAAGATAANTCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGNTTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGTATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGTGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGA
+
2(7:D$-B,=,4E%27*;&/GDB4=<;D9@E,+?'3("D.38H/')%8D$+""CG)F3ABEH2(3C#9!@"!)=+/$H59)%:#::@;>$579?*'"*38&;B$<$<C+:>4'->"H;'!G(+9/HF+!8/&+%886)H">-9!658?<G!GFB$@D2>3>7*F?8>*7F)FDB5*23-</D)C+$*%?G@,0=>34=C8<E$/F!+4(5&E6$C0+=,%,5G:93B8@>*6H8*!6GE07<H%*(0<B+195:>D/H)7@&@G2B,5&.A:5?9D?H$!!<B=,A/!@&(5E@*F1#!G"6*%-C///"5(@C1*2'/F3%6.7DA!!G.(853/"A0BBA+*=G49"&'&80%.%@.F("/.GB656'<E&7:EG;ECA7$.7/.EH5356',5!2,>=#,>H,75D%,,63713#4*&G;"%4)7;,#D/9124<=5%E*+=763D=="8$(;=*#E7G>G,&!E5/70/8&1&
@r795
TTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTNATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGTTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGNAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCC
+
:,D+/H2@8:2H"%+H!6?;DF:F+2/2H@%-2E#A0<'>&%'81B2*5&E7;HC(=54FG@!@!?8+3C%&8=F%8=A)=#GC:$)3/'-5F=C@(-EC+&G921E94'%F'/;,$1/>3%+=E:%2!82B&9#AEE3'028C(:<<0755$3G(BGB>@7H2,C4C.+.2>B9>25+/#''G5AB"1-''+8!H&E>$>CE?+*#3=D/6;D>H(/#.5<:1.?::.F)9+*D5D'=1BE2?E2/H95/D?AFEH2/EGD6-:2)G=(/?48/6#1769C%A*243213G(?<91E;-#A*%(1,8&5"C98-@9'9<A4&
@r796
GTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTNTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGCACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTNCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGAC
+
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
@r797
CCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACTGTTTCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAG
+
1G5,8;3+?BE98,#=%&%G88/=$A2+51*244'-:4!/8;)>&4/6(-+B"E+)<>$;@B&40)D</5*0.6-G-G10/,1&!/(DF!1:;!(5-?5%(34H%-*B)/F-+0!$-:;$-#;/B1*3-0+-&D9CA79>.D
@r798
CCCNTTGACCTCCAACCCCGTAATAGCGATGCGTAATGNTGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAANTCTTCCAGGTCACCAGTGCAGTGCTTGA
+
@(HE%'0::C7"';1:EG"#E<8#A1.";D?1GE2*/D9>A9285F/40;D"*F,'4DA9(?4=88:6<DCG+#/F#3H2;=<>F+G0&11&4611@H*>$:/;2=&'E5;>.'
@r799
AACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCCGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACC
+
7+#5>F@>E2@G$:!&@>=B6D/5.8,'"3/BF3,(2/"3=DG&C;75+AB"&A")=*,@+>7,#D$BH(.-?>)<:+52><2H;>G<.2!1@<$8!E@0(.6378#F8,85@72(,F<$F0($,F317G$#<=-6#;.'1'8C2%:0C@/@@8$$<@>13B067-%A)3G+?$C4*-)6>$?#-G5-E,84;6!G?'&E"F%@;@&>B%&0748538*4?.!&0/4"/A-3(+,?E1--14,97:!8C+A)-G0?H8GAD@/+C$B9;D<311,
@r800
NCCNGCTCCGTCTGACCGTTACAGCGGANGACGGCAGCGGCTGGTCAGCACGGCCCNGACGACGGAAACCACATACCGCTTCACGCAACTNGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGNTCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGNTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACCCCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTT
+
(0!'"%:-D/*FC=7A-17%+5F7(A8#@G<6?729?,;E;#5F#39,$0*?6C';&4$;D7DC-0+$("D#9.1H%?.<=0//&288&+G3F.E3%F'95=(@D6"8-D1H?9,5GG1#5#/.C2CBF,=/:DA?"F8.09BH>8"=B@+E@1>%1)+'C./7--/67H#:7#GF"52#:1=/4'A80'10BH@3"%&A@.A"!,2.?-B*3##6B/'@B69@;#07$E5,@,"6$<=*-970'C>82$6!G/4.64/@%%33=$+;:$9BD-=A4$E.?CC)3F30)/G.?.+DCCA*%3.66%A=$"5.@1!,'BG0>(F'%C.54'*&"87+/=>EA#A7(F,9?-GC5HA%$'&5*%9B"'$.)D8/A"*6G<1.C*-/,8AE3=3#)0B9*B-3-*?>-%7C2H8",3):*B?;$93=D>"B+D22=@FD;E;59:C,7?6C&!?%;8.;3#8?<9;C32.,6D5-)A8/?"8&4H>96D99
@r801
GCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACNGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACCCCNGGCGGGATGNTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAANCCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGTCGTCTGGTCACGCAGACCGCCCGGACAGGCTC
+
G+;/)G92$68D=)C->!.4**""!0*D?9FF=D>""8'HDEC:82F.18'F%9(95ECD(7!D')"$A;&8.A%/$F!-&>'464A"'112?98BB>E>D$"C5FG2$8058'**B<2H*=8)*A4@!"10<50/@2A'*-;B;(.?C-6$<&$@9!;G*(,6@6<$>H89+=C::%6)G/=#:19"0>#F62A&3<,9HB0%G5C8@&<&0%3C*/?=)5*A53;D>>#";!/8G4/#7."*F0<;47>E!336D!#C"<C1">@9G-+;/C,H#96?*:!544<%&"2H2&C$@;*'CA7.41A'!4!9*>E<H?/)8.<D/2<7,8@(6$:,GF.&6='412%1G8512>E>G%3+6C8G!%$F62:-<*<4%AAG?@$E,5=.BF88,-1#@&C3-+<#$5-";*&0?15H?7G&790)>@2/2;!,B)GG..:<<'($%F,B4A#;7B98)-"-!'B,@.)4D9;<$/%)=>'%%
@r802
ACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAATAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAAT
+
/=5AC:':E=BF;)>#C00'5.E-;*A<*)=;,'&=%:B&-*<-BG"B,+>,2B69F'6838?2E03-12(GE#,8%;7A'G&,9B36?6*&H95!6HF9E,$5E6-D3C"B"5<$/)"043'*,@%A25%=*;@<133D!?88"'A<E";!>95'.%##(A21!1)2+(A&H:4'F:73<04C))G)0')%&20+1.2=A@.4!FF>4
@r803
TTNCCCNNNTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGNANGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTNGTAGTGGGTGGCACACAAAGCTTTGCACTGGNTTGCGAGGCTTTGTGCNTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGC
+
(&!*&)"%"$(&%*+++$&(&++&*!#$$*$""%*%+(#&+'&&"#&*!!)##")%#!'(*"$((*!(''+%*&&(&&&("(+!+&%!(!"!'&&$&)&&%%!'#!'((!+#&$(&***)"#$)&%*%"*$'#&*+*#$%(*%!'")()&($"++$&+#++'($$#")$$!!'&()$&!&'$'++%!%+%)"'$%!"'!$#"#)')(%((!)'!*#"#!'&$#%"+)#&)*+!'&*!%"!!')(+"(*$%!%#"""#"$%%$'&(+#('+$!+++&&#+&"!)+&'%$'!&)!*!'!("()!*(*&'!(&)&"$''#+*#+%**&#&*+)'())#)!&"$%)&'*()&*()#&(#$()&!(*%'%&%*!%%((($)""#(+$$("+*")&)%$*%#!&*+!+)++$*"!#!")#(!#'&)"'%("+&*'$&%!)(+
@r804
TGCGAAGGGCGTTNTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGNCTATGTGCCATCTCG
+
C70#2E;%'$:%&,FA17B75<**:?49!>-9D;07*028<1?CB*&,"!.5+6&#D#+$B#(:-#8E%E@3C.*)A248);E.D%:H/%"14F+6A+"1'"9B&/=>B&,08.8AF$6GF(=2618)8:!..>&@;"CD5DGD3B;$:D837>F87C;#7&-+)DE3898/;G@:>57@>5+$=41;D#AH&8/""&.+;03D88F+G;9*%3;G&G4F&B%,91F6@-+@$@<.#7,4F?;6.E6E!;=FG:!5)/CD:
@r805
GCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGNAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCTTTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGNATAGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAANAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACNCGTTTCATCGCGGCA
+
F//*1><*'"4FEH95%$.5!*!?80(-DF;@0!&D!;D=4'*8+2)H18:*A)%7.=C45HC66B9<<A&?;&.>%'.G&.E+9'C8>.+6@0&=">@"-:9./**3G292<")-E8$8H<?@9B&9G<4(39"&A@G")'*2<.85%;C26">D/A".->).C*0!?=.04(1:0(/!&83.)#&'7C9%94H84-&,:+A$?0+.:(D8'*@/9-4:8C"-%B$@>8";83GH=37@1-,=4.A<84$%@/E!#1!-3,2A4"6*B=(EG6?48$A(++G:AHD'<F&DF%-"DA)$D6%0;AAH.-14G*?+)$85#3>'9-:(&9EH&B*#+!";/B+;3-/%1'$E@:91"'8@&BC1A)E?B)F"9;G*6!9<H>?0:;'B-*!500$&5!E/1C',F+,E:7=9FF<BC.#+E2?=B'=)8*76$2@3$9:/B=;5?6+,7@(,G;//="C*<$H/<C&194#%".3.+=7<<.2=B*2&09$4->:>+07+$+)-+A*B
@r806
ATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAG
+
H;@3&G72#7+=':#%,!=.B5,A(&)B1HG&%(>D4$@=FF760-<=1+%H
@r807
GTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCG
+
+D@2=='C$H$)4,/H(H9'/6(+"66;9%)F.DHD56,)""(H+:!D()+3E(-4@F)
@r808
NGGNNNCGNCANCNTACGNGTNGNCAGANNNNNNNNGAACNCNNNCCNANNGNATNNGGNGNGNNNTCANTNNNNCTNTNATNNTATCCGTCATTNNGTTANACANNANNNGCNACNNCNTTNNCNCCGNGNNNATGGANNNACGNANGNCCNGCNAGAATNTAGNNGCATNGAANGNACAACCNNNANNCAANNTCNAGTCNANNGNCACACTCNNNTAATCATGCNNATTCCNANGNNANNGTCNTNNNTNNNGNNGCNATNNNG
+
####"$##!"#!$!$$"$"#"!$"#!$#!$$""!!!!##!!$"!$#!$"""!"##!"$"!##""!#$!!"#!$!#!!"$$"#""$"""#$$$##"!##$#$#$!##!!"$!$$!"#""$##""#""$##!"!$$#$"$#$"!$#"!!###!$"$"$"##""$##!$!#"#$"#"!#$#$#!"#"#$!##$""!$"!$##"$$"$"!$#$$$"!#"""""##"$$!!$!!$#!$#!#$""$#""$$$!#"!"""!"#!!$"$$!"##$
@r809
CGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCANATTGAGCGTGCAGCCANTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACACAGAGACGCCGTTNGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCC
+
"AH$.,7'GC6A$>(H0.<,2D/-!,)3116/37">CEDC!-:DG:DH*'B69%A="E#3%:3@2$&#307&+(@!<8@CH.-6B>E@1/>*:";&*(DH3&)=##7A.B&AC'%!%!>H(;,3G$.<6F3B(",/C<*)H$.5$2$GH&C5?1:>,!,7=)H(-(7,88>F-,308#@C'8;B"<9B>='2.?)C%8:18'+H&6.:.G!*9257*-H$E0671D'B$6B3-298-<;6=*9-4E*(:972-?*FA5H+*!+F7<.$<&<2&;?,'=#)&1,>?&3A3AE5=>DG).;(+3""D+095CC!?8+<9"/.>./2&%##9D$&2%!3)41A5
@r810
ATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCNACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTNTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATG
+
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
@r811
AGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATCTTTTCAGGTCAGANACGGAAGTGGCCGTAAACTCCACCCT
+
"&*#+$!+(('")()&*(%('!!""(%"'$**$%(($$)**$')%*$#%%+*+"(*!!(((&)!*%**""+&)+&"&$#*!#%(*!*)!"#'!($"'%'$(&&++(&(+(**+'"("!"*$)((!(
@r812
CCCACNTNNANNNCCTACNNNACCNNTNNNCGNCNGTANNGNTACNNTCANNCGCNNNANNNNNNANNNNNNGTATCNTAGGAANCACCTC
+
"!!$!"!!$"""!$""!#"!"!$$!"#!$#"#!"#$#$!"!#"##!$$"!!$!$#!""$!!""!#$"#$""#$$"##"#!!!#$$!!#"""
@r813
CTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAAGAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTCCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGC
+
A=C%HH*;1@#(+;:)1B.D4+8F"/,CC%!G@'810*?(0%(5.2)643&%2,90<!8.AA2G-4?>A>$%A"C79%F1F&H,G648';#<'<GF>4;!'.1;?6E8@F;C4!@3C@78E4#>591;6>&>!H%6A..7$'9>,(49=6<$G!CFB40120>$35<43A+6?1':<6E/?)A,0@3G7/D;D@?=0=#3BC9/+A'56*F0>7()5G-D@-,$3008ACB-8'&!13!$?.C,8!8.6EE57EF&:;9.33=.&58'(3.G2>(%,3*<:?2A):!+/C>>29C+G*!521A>%3723>=,4:"5BD#3&+(C/.=%4!').0!5;+H&E87$8*/)8AB
@r814
NGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGNAAAAGTACCGAACCTGATGCCGGGTGACTCACTGAAGCTGCAGACGGCTCAGGATACGGATAACG
+
(:-*9">G@;%273.('(3"C?.AFHG3**:-.?;"@B''&."0/F3$<E24&<3=@-:!9(?2$FG%?409$9"()&3@A8H*%*/22!'<,(>HA"2CA?#H
@r815
GGACANTCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATNAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTA
+
/1!3E5-3&)!B."@(#:50C"*8;*D'9$95$7BC;&>7/$H?F5H&D,"D!,7%22:)G=DH*+;$/.(@EG8"#)3)3/@#4+AD##:!1B$G1?=%H2B533-*9-G;-?):*55)?;)D2@4=7+):!
@r816
CGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATNCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGGGNTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCNGATGATTACGGTCCTTGCGGTAAATCCGGCATGTANAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACT
+
G)-!;29@G/?':'.87=''-36228>)?8(D=CC.,!B48C?--1"!6@?.D-F>!('/;'FH7B407E+?&9:!C(=E=&3D!,5*H4">@.7!&#"6?H64D"%($-/=/FG*7!<.'@G$)7BE"7;;'1B)H=A$,B##:<!'9("+G)?D!8CF3(C/H#%?H@"9=$42'B>@*G>A85./(EG,;<B*6>DB<32.'70B>>A>%C=>8?6$'21*')#5H'$97A581;C>F:=!920*.C#+$3?@F3%H.H5@4-".?62'&,"/8&CD&E?@H1A9(.:(C*%)$!&$7<2'
@r817
GCNGGTGCGATCACCCTGCCNATGGTGGGGGCCACCTCGCTGGCGNTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCANCAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGC
+
&%"+#"'!(*")*+"%("(%)#'$#%")")!))'("##"#($%%)!&$+$!!)$&!!'"&&"'*"#!#)##%!))&$%("*!(+"$)&(#$))*!'$&(!(+'%"$#!'&*%%#"#"(!!')*&%()'!+#"''$)#*$*!('(""(*)"$))'&$"+'("&!#()('#"""&$%))&&"&$%'%()!!(&&())"#+($%$+$$+%&("""'*!'##%*%+%(%&#!)&)*"'+'(!*&%*$!*#'!&*'$%+$'*+$+*'$('##%($(!#"&&"%''#)*)!#'
@r818
TNGCNNNCNNNACGNCANNGNNACACGNATGATNCNNGGNCAGNNTTCCGNCCGGTGTCAGGGAAAAGGC
+
&'''"!#(#&&(!'"%)#$**$%&(&#"(*$'#&"#*$'"%%)!+$"*+&&#&($)#!%$%$##$+#%)"
@r819
GTTAAATTCTNAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGG
+
'8D8@>1H??5(?+8:'2.=)</"'@5A.HGB95"#/9=:6=34FA'#12(AB6,7&<GA<#(8.$(.6>&C.+">&"C,-@-=5;G6.&2:1B0BHFDHF'(A-=$92C=*D.57H4
@r820
TGAAGAGTTAAGACGTAATGAACCACANATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGAGAATA
+
?@E603D%508=%<%D*(9C"5#;)@%8%-F.C=A=?H?E3=;%)A>#G>=9.#"5'BA$.H<)%17H,2B5H9
@r821
GTNGGGGCTNNCCTGACCGGCAGTTTCATCCGTGTCATNAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTNGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACCGACACGAACTCATCAGGGTCTGCCAGCAGCATCAGCGGTGCTGACTTAATCATGGTGAACTCNCGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTA
+
#!$(')#!(!#++(((#$)#)")!*+&##)"!*'*+!#)%($'%))*%(%)"**+#)")'*"!)*''(")#+''#!%&+%#!(''(&&!'!$++%"$!#&(("**!!"'"*%#!')"#)#*"'"$*)!!%!*#)%)'$'++'%&%(!"$'+%)$&(#+("(*$%")!)((+'+!(&+#*%&#%*##$')&"!)%$+!')%!+"&#!$$!$!%"!*%+%(&*##%'%+"))"!#)+!(!!+'#''#))$$!)$&#!')+%$*$!%&)!%#%'$!$#*")(**$!))'+%'*+)&")$*++!*++"'"*$'"%+#"#!+*+#*(*$#)*'!!&("(+&
@r822
CCGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGCATTCACGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATT
+
",B0A:10?1C"HG88=CA5-'?#C$+'*%38'+>&.>!/(8E.)*$6H,66;4D#$*3:EH=!/+<95645B=*92?4("'D(G#%>*6H383A&G(-/G'#<-B*H-@5;2C#?&/2=&#61;%>AH)F74='9(,;7#2F,6?
@r823
GCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCNCCATTCAAGAACAGCNAGCAGCATTGAGAACTTTGGAATCCTGTCCCTCTTCCACCTGCTGATCTGCG
+
./52/9CG'E,<6FB"@=A%:2:-G-+5(*!HBD19D#?HC89"0-CC-/6:EC<$(F+54HF>F,%6?4%01?H=2!+F"&$.:1"&4*#$B;1/2?,?)3F)2@984&A-
@r824
CTCTCGTCGTCGTTTCTTCTCTGCTGCTTNTTCCGCTTTTT
+
6+3%F90$).#E@?,H--%;4$<AF?H3.D>:;DB;>7?D/
@r825
GAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACANAGTCACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCGAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACAT
+
"&*(+'&*%'")$"*%&"!&#'++%)#%$#)!"&$!*))*%+$+!()%)&(&("+#'%%%+*$&&++&'&#+)&('!!!)(#%%+")#!!+%%!'**$$($)#%'+++!$""(*&)&"$"#'+)&!#$$&#($%(%("!+#%)$+%!)))"%*()'++'&(%('!&$$%$!"!'!)+$%&%%&'%!"'(&%#%'))%'&(#!+*&!
@r826
NNCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTG
+
!3&'-',69303;BB-"*F6AF+*,@6)#!;E=HF<%<%C&B&/B64E;*2+/*#H(GD0<;D*87
@r827
TAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGTCNACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCNGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGNCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCNCGTCATGCATCCTCTCCGGATAAGGCACGGGCGTGATCTGCCAGTGTTTTCTTGTTGGTTGCTGNACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCANGCTATATCTGCCACTCATTGTTGTGAATGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGTATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACNAGCAATACATCAAACGCCGCGACCAGGAGGACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAANGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACNAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGNGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGNGAAAATGCTGAATTTCGCGTCGTCTNCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACNCAAACATCGGGTTGAGTANTATCTTACTGTTTCTTTACATAAACATTGTTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGANATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGANTCGGCATACAAATNTNCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCANTCGCGGNGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGANGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGC
+
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
@r828
AGTTTTTNCATTGTACTTTACCTTCAGCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATC
+
GGF0???<E7C#%7(=BC$#>=,5!F1&4F1#;(!'-;;@B"B$+-&>F$$B8;,*-A-G$D44'A(":D73C)8;'
@r829
CTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAANTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAG
+
'2-$?75H0@;3747E8:%;<-(5?&*:1H*).+,A$@?+&A6#A8/"&88:75+1$6HH@&+-2/DHFA+%1(7C*+<#2E40.'!DD1-E<6AF!+$B.$*%F0H$/-CA+'DC650#&00E'-E;%;7D154<#5%-+B5%3605D7#6)2-,*G/74G=7">5)@G0-D*DB1@%@FA#<7G;1.D5+A;/:;;'>"AG?!*/,HD$7?>F%E;EG4*$3)46=B:"(*9B.3B4BA$;FD?'6H(9#+HHD<2E8C?:*E96@34#2HB&+."2H;/1,C3
@r830
CNNNNAAAGGACCGAGTTCAGAAATAAATNACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTNATCACTGTTGAAAACAGCCACATAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGANTATATGCGNCACCTTCACCAATAAATTCATTAGTTTCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTNAACNGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGGGCGCNCCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACCATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACNGTTCATCCTTNAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTT
+
%%"!)%&#&)%+'*&!!&#"!)""&&'!&)&'!*$))'%*'&%%('#+##$)(#!$!!%$*$((%+)(*!$))$%&!&*'##*#!&)'+*!&+'"%)()'#+$+'("$"$()++%$+#+(**&!#')&&''#%%%"))#*(%#(+&)"$'+(#%%)+()%$#%&(!&$!")%!"$$$'%'*"!#($!%++%*"(*!%"&$''"&!#$)*%)&%#$((&((((&$$%$"$#%&#&$(())$!(%&+($$%)"#""$)"!(%#(()'+("'%*"%*)'*%!*))*#!'"'++))%%'#$##)+*(%+(*"'&+$+&&$*&&)!'+&$)'!+)#"#*(*)+))&*)&$)&'(&*"%"(!(++*&)$%!%&!+#%!"!)++!%)+(#+'"+$&%(%!"#!*#*#%%)%!'#%)&)$&&!'$&#%)%!+!$!'!'+#%)#'!#!(')$#'))"&+$#"*&''!!"**"'%!$$$)!")#!$+'+(*!)$)%'#(#((!($*$&$%$#%&$#(*%#'()$)'&'+!)+$*#+(!"%)"*!*#$+&%'%#%"'!)&%"%($%%'!(&''&+%&)'($$"#"(+$+%*!+"('$*+$'+&)('*)$%)(&*&%'&"*!$&*$"!!)+("+&($&+##!"**+#%#*&*&''%!&()%&%!#(*%
@r831
ACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTC
+
%+&'!)('$%#+)"*()"$(*!(!)#$)""%%!!&#&')+*!)+%'("*'&(*#%)%*%$%'+%##!%+$+(!'%"&!%*('$%*!*"+#$("+!'%&(*%+'
@r832
GCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATNACGAANAGTCGGCTCAACGTAGNTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAANGGTGNTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACAACATTCACCTCACGGATGTAGTCGCTGCCCATCGCANTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACNAANTGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATG
+
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
@r833
AGGGGNTGAACNGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATNTTTGATCTGACCGAAGCG
+
++')#"&!$#)#(!(&'#$&)'!&&$)$+#+"#*&!*''%+''#&$&)#$""#&&)!(+)$"*')($%+"
@r834
NCTACGNNNGGTNNCTANNTGTCTNNCTNTNNNCNNCAACTNNGNCGNNCANCA
+
$!!##""!"#!""$#"#!####"##!"""!!##"#!#!#!#!!$#"#!$"#!$"
@r835
GGCTTTCANTTNCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCNGTCTGCCATGCTGCCNGGTGCACCGACATAAGCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAAATCACCACGGTNAACA
+
$"$#)$%(%(*!+$$(!%(*$!)"%"+++&#$)#++&)#*(&'(!#&!)('$'&&(*(')$*($%&$)#'('+'*+%+!'+&%"*)"#+*%*+&"!)!#+##%+%"($&!)$)&*)!)')%&)!#%&+#+$#*%#"'+%"#"$"#*%$(#%*$(*!))&%+)+((!%+%'%"%&#'"&&!"&+!!!")")&+)!")(&&$#&&+!%$&))&+)+#$)(*"+(&(!##**")+#"*'##(!)#&***$$&+(&%!!'+*'+&!+#(&+'"&$)"+%"+%&+&#!&$'**'&%""*(&"'%(+)*#")&(*)+*")$+%%!"'*(+!''#%)"%&#*)%**
@r836
NTGGTCAAANTGCAACTTAATTACTGCAATNCCCTCGTAATTAAGTGAATTTACAATATNGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGNTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGA
+
!')#*#'*+&$($*)"$)$&&!!)&(*$$$"+&'(%"*+)!(*$&%+&(+#!%*($*&!""**)$$"*!(*"&$$&%$"*(!**!)#!$)$)(!")%+++!)*&!")%!*%%$#*$#)'#*%*!'%)%!"'((("+*!+$$'%+('%''+!%&$(!$"'!*"#'!!"$#$$)""'!)"#+"!#)')&%"*!+)&#)+'%')#**%$&$!%$!')!$()!!#)'*&('$"$'"(!(#'!#"#&
@r837
ATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCCTCATCACTTTTAATTGATCTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGNTAATTTGTTCAATCATTNGGTTAGGAAAGCGGATGTTGCGGGTTGTGGTTCTGCGGGTTCTGTTCTTCGTTGACATGNGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCAGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCACTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGNCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTNAATCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCAATGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATNGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAANTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCAGGCAGTTGCCGTTTATCCCACCGGCGCTGAATACACGGGCGAAGAGCTGGAGAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGNTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGNTTTGATNACCAGTATGGTGGCTAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATNGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAATGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAANGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCNATCTCGATGATGAAGATGCAGACTGGACTACGACCGGGCAGGGGCAGAAATCTGCNGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGGTTCCCGAACGGCACGGTCGATGTGTNCCGTGGCTGGGTCAGCAGTATCGGTNAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGGAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGNCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACNAGAGCTTNCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCNCCAGTTAATCCGGAGAGT
+
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
@r838
CCTGCCCGTGCNATTTTAGCCGCGGCCTGATTTATGCTGNTTACTGTTG
+
+!*%%&$)+##)$'(#**''$)%#"#)!)%)!)"'%%#&#%(&'+(#&)
@r839
NGGNNNGTTNTCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTNCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATAATTTGTATATTCATAAAATTGATGGAAAAACTTTTCTCTTTACCAAAACAAAT
+
!$(!!'+"%&$$"&$#%$$#)%+&"$$'$(+(""+()!%(!*)!'$"%!#"+%!(*($)'"*%#+!#*(+"#(#%+)$*%&$#!$'*"*(#%*#$##'%&&')#&&&#&+)%*"$$#+(#+#*!!+%)'("#"+!")++(!'%+'($"&!!'&+&%+!##"(#)%#*%(#$$!!"&!&$+)$)#($'($#&#+$%#!*$&''$!+"#)'%$*'*'%""()"*(*"+"()''('#&!+("&*$$&#)*%'+%"*"!+&&#!#$#$''&()(*(+$(#('+$""!"('*(%%+%*%)")#(%"&"*%$+!%$$$&(#'*!*"*!!%%'+)(##+%#+()
@r840
TAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTNTCGCCTTCAACAAACAANAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGNGATTTATCTTCTGAACCAGACTCTTGTCANTTGTTT
+
)+#*#+)!#"*++!)!)&"$'"!!&%$'()#('!&!'$)*!#+!")#&&$$$#(**(($$+#+'+"(!$&*"#'%)(%##%+#&$('&)#&!!%()*(+#'""$"++"+'#'!!'!*+#!%&"+)*%"'"#'"*%%*$&(*(+""&%)'%$+!+'"#&++)"*)+$&&$*%&!(()'"+'"+"('
@r841
GTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGCTTTGNATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCT
+
A,(/B%H*%BBA"<2(?B7G$:D%D55<+G"DE#G+87'?A<&,?#1=',#>E;#+F((?6)-85)(#:07-C:()7G&%-!=;!!72B5*.&&/EB)"=;H&,@;1"%EF.E.G@8.;5<:BH03D25C6<*"!EA)$+;7F='C&/<<A?8"*5))9!0C+!&C,%)0:1D*;"@(G..A"#&,',=,6%9!3'/;<C/7AF'D$D:0?8!$C4@:4<0$=<1#D%&+!-*!71+.',1:9GF3<)"B;/..#*&#H&8880DH792G!5@0&'84"?@9(/>?/?&8C'5H2%'D+*)/)"6;,-.!*5+9B(3H@AE/364E6+6EF,->#D)&<5G$?B!F#FH3.+H8A/4=7$$:"H-.G"G"$@6=))@DG"54=-"H(7:>DH6*798-1(9"+,%3C"-;;))'00B-1$14)596>7>@77$""F=$D1B$$#;9DC29."'G&+0>A<75()";B"*%(>?-&C
@r842
AACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGA
+
E1D42)2D5H9()!D/!*-H+;1*6=#"#D9*H&F(D;+$4+>86CG8;G3'+E?F>(H3$44<B/554@&!'A="8F:/4-?H,56?33A$!4%51./85<&@*(
@r843
TGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTCGTGNCGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCANCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGTCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGCCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTNAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAA
+
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
@r844
TCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGNGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCNTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAG
+
*7<A=60/$1A$=/2#G>"%1;,G90"3#;D8.&A99DH>&;/@2;7EF68??$-3#;/A.7>3'9B+1F:&&:AG2D-*E"#1+%E?:$35DF!,)'1/C2'.1B85&#H(><H+B@=4"-8<+:!A?.2A0'@(;-=F.+2@"92A*-&%"3((H>$(/'%G83E)#?,960)0!(F073)63'7?=0#+7DG*%&3@D!"?E=5=--G'99B50DD<"C!<64<.0*=4C"&$'G<*0"(2'B+1"-3A:+2:F@(D>#FE*GG$$10($>3&!4>AD>3F&.A(;80=3H#;4EGEA%7B8<65(@>30>E8&)>6?&*1$74BB?AHD2E-;,4-6'%!"C%,)H'A1C2D?3C<+;.'%;HF):A"?3C&D1*$H(1>!+-??>A
@r845
CACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACNGAAAGACGGNCGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGNTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTNGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTA
+
2;C5-G86+>7#?22G8;A3$5G!,G>1&B/!'E<@&)"6E%E;><%=5H;8+9!>5E8(-F>+!<911=:(-!-?4:*568::1=28,'E$!G:G@;>-#-1='5=/,B'&5,$66A@8'/405D<@2;%;),/E;=1,;%?H#379E;H4+,1:.3%*B4&*@(%(2&,9<"/F8*":(FC@'<E52H*GBC%3=+!:F'C?0)9)0&#!!&#D)4F0-E%+<CD9B#:'+*G#56/:=3<*GCG1;#BB#$7(D.1@-5;4-$%G+18>H#-.GGFC0=EH:"0?C"?!;*%,;C?>?"3%!<,@AG46/)G1@2F?<7<!2-H+-%FD)4%H)B02/4A>>?<*,BAB-!@,9*
@r846
GTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAGACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGNCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCCAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGNAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCNACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTNTGCCANGGCGGCAAAAACGTCCGAGACGANTGCCAGGTNATNTGAAACAGCAGCGNAACGGANCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGCGCGACAACGGTATCCTCGANGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCG
+
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
@r847
CATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATNTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGT
+
?''?EA+.G2F87#?*G0#<;?+5$.HG:8,>6&@)6=7GD;>1-A#-;H-:-)&=6D)%!,>F7=4B4*.843':%?5?7&4@!3B?"(:$,!DA+'HF1B0740H-'B/71?7*68<=-H:,,,?/@8+H,="EF;&%"#"0*&,CF&G!#(&&#?)(6+)$H2,7<$-A6>(9=32156C89',>F0;(G6.(0"B*(,,D8'D(8%9#.#$.73G9>B84-
@r848
TGCGGGCAAAAGATGAGGCTGGAGATATTTTAACAGAACATTATCTANCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGC
+
CA"**?FH#.;!4&"3A*64F0,0,6(%&>(*2?1&,B470C>9#ACD(/HH$$3>=$F"A=0+F'#;5>;4!<4$:9-6HCDCC;"'0,8<(!:G5,>+E'.32-)#=,FA"<:5@+AF8'
@r849
GCTTTAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACGACCAATAAATGCTGAAATGAATTCTAAGCGGAG
+
+!%*''#)%'%+#!'%&+%('&+$*('&'$'$%$$&%!*&+%"'&#$')$')'%%&"*!!)+(!'"+"%#*#"*
@r850
NNANCNCTATCCAGACTAAATNCACTATCGCCACTTTNATTGGCGATGAAAAGATGTTTCGTGAAGCCGNCGACGCTTATAAAAAATGGATATTAATGCTGAAACTGAGATCAAGCAAAANCATTCACTAANCCCCTTTCCTGTTTTCCTANTCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTT
+
'#*#%'+$%$$!'))(('*'+&'((&#"%(*&$')(&")"%+!&*##!#&%&)'&$'(!&**'$!("$$%#")*&(++"()")!*)&*"$*!)%%*+&&'++"%#")')"'"$$('*&)!)")(($("*(*#*&*&#$")+''*(%*%&"+%'!'$$!*#%#)**!"*$!+*&$'$+(*!&*#++'&(!+**
@r851
CTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTNGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCT
+
-*0&8%9@H1D)GA2#*>BA$5).E,0.!1/);4H16B9&G=+5?%H&B76E@++3A*%&4.?-3*F>:'=;2H/:H*@;#>E=6<>B@9$:;A#6?6,&+?%:?7*-''-$+&$>+GC3#)"$/4>1'7.%0%)"98//@;&F4H$GH1)AFA)A+=DF7)'7HD*01@;0:61$'+%!&G18A1&/G2!:8>%D+=@6<2
@r852
NCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCANGTGGGCAAAGTTAAGGATTAATTATCAGGAGNAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAGGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGT
+
(?$/(A@'>-6+GE=26*9<3@.6;41@6<=9H!4@3.<2B5<=;3H-%99&=9;,@:!#!27,1.#9%':."!FC$$4;B9D!%83:#-,B""*;A!/FD:>-$,E9*1536&B/A';"7).7;DA$#-':C2)#&,%-A#,D0+-D+?%'D*&B=<#;H/=B@<;/05>4>1:*'F./7"C*D-=05&+7A38"#3HH2F8+D'131*;8>18+#&6((G:!>683=AB5)FC+5A9#$B7##54AD8
@r853
CATGGTGATGATTCTACTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCCTCAGCTATTGCCTCTCGGAATGCATCGCTCAG
+
.HD38157(2#:4(+@@:&B4=A90A&9(#*522757<#.?7&A&3/;'6.#*CC>,6-<G:0352EFA(%=-?#,33("A?3D9<17:<%#476G;=-G(C4<6!5&,*@62)4!<*A66,##24*B+D4-3<8:>78"3/?7*/)A,?/7
@r854
TACTGATGCGCAGCGCCGCCAGCGCNTAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCG
+
.2//G*8D#A<=BF8GB#.8C1B.14/&CEHD+CA",:%6@%,D.839A19%'0"047?;.(@+GG(@);%*>4"551$3%E-')(32D2(G5.6:><+?:@D.&DE7B3?(@,/05:49+.&#<H?B.!%5H&63"#>+F$*)+?*5?+(.F-H#>B)>!(:47&#:*A<$H)#:72G(&F(9!);5-"*D@.#05#2B%9=//&;,.+FA6B=D8*3>8:
@r855
GCAACANCAGNAAAAANCNGNAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGANTTACCGCAAGAACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCNTTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTNACGTCATAAAGCCATGATTNAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGAGAAGGATGAAGCCGAGCGCGTTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGCTGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCNTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGAAATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGANCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACNTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGNAGCCTGTTNGCATTCANTTCCGGCGTGAATGTTNCTGAATCCC
+
(#%#(('()!'(%&*$!&!%&)*"+("#%*#(%+++$**!)+"$&'*%)()*(#%(($($'"$!&#"+%)(**)"+#!!"*$'(+$&!!)(""%'%)$!+%&&#'"'()#'"+#$*(!%+"!+#"+$%&!&+)%)*'"%((()*"!"+"!'&#(+&%#&&!!(%#+'"&)!&*&#%%)*%#$**&')#*)&('#)++*()"#('*%&*(*##"+!$($(!"#$#&$"$#)%!!!+**!$+*"%'*(++$$**&!!*&'%###&"$*'$)((#)"+(+*(+"&&'$*)%$'"##''**$%#(#!+%!+)')!(&&%+##%($(#***++)'+)$($*"!(!%(+*!&"+$(#*''+')"+#&*"%'!%"&+*++*%"%'+&(*'!+"&%*!)$(&$)*!#!"#!$+!!+*"%*!&&+%")*'+!#&#&#!"!!&*((+*$*#!&*"%$%($$!'$%%#)&""'!"%**##*"'&'+"*!+%+*+&%$$')%$)(+)!))(()!'(+*$$#)!$(#)**!##+$!*)$+%')!("()+'"&#(!'#!$)&$)*&"""!"##((%#$$(!&')'#)%")"+$"!(#((#'#&*$+$$""'+"#))#!$*%&#$#**+!*&"*(!$'#'&)!+&&!*$(&$#&'$(%&&#"*#(++$*%*'&+)#""&!*$*"'&##%'))))()#+&*#))($!+"("%"(*!+'+##+")((&!!#''+*""$*%("+)#*(!&#)')%*%#!#()!+$%)(!#+"!*$(%%$$))!(''"#(+(!!)#('$)%#)"*(*+)**#(++##&&)')#&*+!'+(#$&!(#+*&+*")#+!'!*"%)++#('*)!&
@r856
CTGCTGGCGTATGNTCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTAAAAGGGATAATCGGCGTGGCAGATAACNTATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTNTTCGTAATCGAGATTAAAGAACCAGCCACC
+
@F>(>(-04"E%3"#+%G32D8-@,(H%#G-:"?D&%02D!<"&3F)3%&>>,HF2#:9H!:0%=+=3B1H!6#H.H:?-@&FAG6A1$6G8-)2=7#B;8A3#$**$+4:0E.?<!@*/8/GF/909F)'/#%+'8(58)7<63$;;G@B>%?12EH:..+>)1!+(8HH:,4>B.:*<57/,)'-1&C4,71A12@E5,96?#!?*5>#='@F0DH21B:49!2@2>E"6+("''9)%!?@4.);/?C01,F=@23,7CC!;/7#FH=9@+;2
@r857
GCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCAT
+
97&&9$A6=#C@@7*';$?8E9#'G/0E1E(C6#4+<6EB-5D3!%)/-&1"A23?,:0/*8*')
@r858
CGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCACCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTACTTTGCATCGAGCGCAGCAAAATCACGCTGACGCATCTGCNTGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGNATTTTTGTCGCGCTGGGCTTTGTAGNTAATGGCGTTATCA
+
?8(/#G7?-*4>B)8CBD<8?(+6(.$403H+,3D$-0=.CD.;>4G"8@::.8-(/(H&B8<&ED9C%>=)#05$#+F$E0<?D%3D9,6GH0-D/,!#/8,A9'9-%;,F@HB%$C3958)A/H9,3(0EH.(A;-=.<964'/6)'G7B>&H/9D9!"!C+34'$.;7'GG.EG""'5.,*$%#G3'B!6@6,6%2"3G46#6+"?<+"?G?"50=F:B78846@(H0*#B@GG&!4)66#<D?;DG<?H42$:4()@?8+,E@F<?&>(BGD&?!.:A@5A+!,42&1AD
@r859
CAGCGGCACAGCCGGGCGATGTGCTGCTGCGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCA
+
B)H+G3:BG:BB<&1G7-0E4!&D#9A07<708&G6),4')C+*AC:,-7H:=*%;H(-)F0>AF1=A0"$FFF*3#EF2"/"@"F!)/A<<9*?:0
@r860
NTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGANGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGAT
+
"*4!<5'F<D"/5)>D1?/,=@*@"-7+7!(09C#&9>)@B0!+E0&-G'/4>.E-6BHCH+@:?++'A$#">H!<83.<&4>4+.31".;:A2>30BC#20?',"-<.1,%4?F.CG,2(D-;66.$-3(!+)C=.?>2)("7+GA(D:/),?$H!E/8,%%?FC2*&;GH
@r861
TTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGGCAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCNACCACTTCAGCGGAGTCTCTGGCATTCNTCAGTTCCTGTG
+
<%H?=.D)0')":EE;H:/$"B4F&?.A3G@HG$?$FD4&:@CB<@#D<@FH736C1%3+,*?(#90HG$F:$G?A*"=B5&G;$74$+B$<H1//>G,$&0'FC0*B!2A9BGEF+9%BC3!88@996/"3!@.DA4CEEC(*,:)404*+3-E,244<389A"(C:/;*&$>5ECA1.;D+14BC:&9DC2+7'6
@r862
GTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCNATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTNTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGNCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCCTAAACATCCCTTACACTGGTGTGTNCAGCAAATGGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGGGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGNTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCNGCACGCGTGCCTGTTCTTCGCG
+
'D('$*1H9/%./)B705$-4@G"%%,93(B)CC69+=&=-BA!3F><H;E>2.H4(CB-!#E4B-.#!63>"#F;12H;*(1<&&?BB@85(.<2E7;H?"(?$)E04"H*DBH<D1B1*B+B@;;.5?"(/&)4C%$E>=E"2B"41HB#/H3$&7D!9G&!!A*78/"E"5A%%%C'0)%<2;,,E#2H*7"+$='7/8-*!)DF8H%?%3-"G*;F:8$-*1D$*;(EBDB$@D.'+C"AG>E:D-7<24F94(#:;3;@*.?-4%2C.2/-DC=#"A!#BC312:8#=6>G%:HA=E"6)H>1@;5,B'D>8B0E,C(A4C8@2#%@;,10!H%D!>/12"4D:2?('98-D<8C1'#&.82:,C6$8-/2>-HF+:(4!5//;;$E4F%E,1*!:->>8?F7'<45!&(%A3$7B>F5/#9C
@r863
CCACGCGGGATGAACCTGTGGCATTTGTGCCGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGATATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTT
+
=@6@83#,+@H%<FG1FC8'9G0AH,:<EF=?6/4(F<<B3B,&=F<*G5$*+485AE3-3:#B4!@,?H7/G&CA-!@B6$F1?<FG1F;%<227A>0C*0@-13D53,/7"H<1&D$/B!E3:B!?<+(C4"/>C?=50D2+6*H>*3)$@#")H<H+705F-+(C/B,/E#GF49.8B?=5'#@7(=,507'8?122:?;G<G-E8E9%G3%DC<B=!CF))>=?*F5E%*71##63#'/A?$1&(&/8>@1)1/7(,*46!9F(D**B)G=,6A;!8!;*AED858+@"F(#<(!0C<%A04"./@<""12
@r864
AGCGAATGCAGGGNGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCNCAGTTAGCGCACGTTAAAGCTCGNTCGAAGCTTTCTTNTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCNTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTGCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTG
+
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
@r865
CGTCNCGCCCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTANACTTCCGGTTGCTGTCTCACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTAACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATNTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTAGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACANGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAA
+
%"&%#)!#%+(!'$+#%%"*!)('!#'*!+!)##%&'))""!'##&#$*("**+#+&$%)(*&)'#++(*&&%&$#%(+%&&+$)"((!%!%+(&&(+$*"'$)#+*$("(!)'(#%)+%#*)*%*+"$)(*!**#&*#$$#&!!+($%$**#**#$%(%+"&*!)#%)&%*$(**)'(($*($((")$+""#++!*+!()##"**(#"*##(*+#'&#+"#$!")*+)$&%")*+)(!%%#*$&(*%''+#*#'!"$#**+)'#+$"%)+%*(!&&+'()$*&'&)+&%'#*)#!#)!!(!%'#'*&('$)*!&'(*'%*!(!&%(&!)++!%%*("*%"#)+#(#*!++&(&(+'%!$*#(!*$*+)""$"'#+'%#
@r866
GATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATNGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATNGCGGTAGTAAAGATTGTGCCTGTCTTTTAACC
+
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
@r867
ATTGAGCAGTCACTGCTGCGGTANATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTG
+
#5G%F5!2A0C+.3G"0-4*,@A.-<-A):>=4B:66!-H4/B&E?GE$"G*B&+?!DF$9'01GD>78-18H3!EBEAF>?G4,0-:E5C"A>2H(,:4"*.+,$?=H9=#0#2)",?)":7"4<:E8/0/%68$D&F27%2EB'F5G->2>=F8!;.?+:1,F.8$/&>/"=08DD!4)HF8H><3)0=1-$7!;F"E5D(984BB<FC+/
@r868
NACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGNAGACCGGTAAGAGGCGGAATATAGGCGTCACCTTCACCAATAAATT
+
$56?%!-$!?#3!*F%&%@)B:#C.4!(92G;G>*7,;&-$@B7CD?G!E>):+#6;4.B(-AD!'H@)3".!3#>HB*$?G.1=%0&%H/9+5%@E>-%51'5%*3.B7:1@1/DBH37GGE8&CB2/#0@1>D
@r869
TAGTATAAANAAGCTGAACCAGAAACATGATATAAATTTCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTT
+
-;+32!2H2F'9$?=H)2%FB9/&<F((3,3H8()&/&'HB396;C2/((<,D2.?@=/+;1':506(A@4%ED222C1<@"",1*4(6(6C:3!F@H.6?<68-+!*#=D>H@H:H?D89A5=!2#9*0A'@-@36@G&6$2#7$#/76%C:>-+BB$G7%'469"(C:..A8
@r870
GCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTNACTAAT
+
$H$$%@8(#=(?/:EB<G2;B6B4883,3D4"D$.39)<;=,?'<3C(E:5FB3:<"<?4/%!;++>:?:&2#*(77@19<5)*."95CB6%5)0F9B+-1@.G1D=)2?$%G5-<7$*00'-!,6;C6;5<D<<:#4@@CF"EB0:>
@r871
CAACGCGTAACCCNGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGG
+
6ACE71>E(2+$5/"$E;1:E!&>=D5"#.:4)G*H!#4;2<5+3BC;?%8A-.="36"<:/2$>
@r872
AAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCGACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCNGAGCAAAGGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGG
+
F9(7=07/,%E@&/E#-A$33*."6,#>G<?5)9CF8&''<(2*4:;-,0A+)*,/B(H%3971C6EF$<'2$1<72F#*6F/B4/.HC4GD(6@F+%$@.%>$.BG9+5(38!1;6?C*856,4/B,
@r873
GCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGGTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGAC
+
+!*%(''#))*'&+((&*$"!$#'"#!"*+$!#!**'')&!&#)'%(+)(#'*"&'%!"&*"'$!+"()*%"#*$*#%$%&*(+)*%&''!)!(*%#!(%*!$%*&*"'!!*#!&*##$*$"&)#!#"#('#!$&+#%''&&$!(+!
@r874
CNNCGGAATGNGATNANTNNCNGGNATTCATCGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCAGCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCNGATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCG
+
'!"%&()'%'&$(&%#$&#"$$"(#)"%&%!()+)"%*!*$$"%'&*("*+#!+$)")!'#')!(#"'+&"#'""*""&!)'(*))*')(+"!%++%!%*!&'&#'#*%$(#''"'+%%*)!$%+#()(*+!%)$*()%#'&&$$#+"+"()($)&"%&+""%$$$"&!%"#!*#+!)()&'*'"'**"$%(!#*)&*%%+'"&))&!#+)!%$(('$&
@r875
CATNAGGTTGCCCCGTAATCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGA
+
=6;1+9A09!E<46B=>((2"<+BD#6-0E151/D(2/;!5D#<335E84*,5,6325G<#:D&-&:@32D(:?*<A,H(3:;+:&*"8&%(+9*;47H7#?8@%('"11")EF08(34.6GEH!B-;$4.G?>AC,5)!AE:+E040,**
@r876
GACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCTGGGCTGATTAGGAAAACAGGAAAGGGGGTTANTGAATGCTTTTGCTTGATCTCAGTTTCANTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTNCATCCGTCACGTAATNTACGGGTGATTCNTTCAAGTAAAGATTCGGAAGGGNAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCACGCGGCCTTAATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCANTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAANTGCTATAAGCANAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGANTCGGTATTCAGAGTCTGACCAGAAATNATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTNCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCGAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTCCTCGTGTACCCCTACAGGGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGAT
+
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
@r877
GGTAACACAGTGTTATNACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGNCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCANCGCACGCCGG
+
"6?#@39$C")+@HD@6!@64D-H17%#C8"2$*1)7).@#B??.(;D@-=?7E:.=DC*@'?0(*,2(28/81/,5@@2H%1:3;455(EGG72830@C6@B2/>(,$%4&5@A-5,.43A65H,>@EGB2,!!(<.E30A/*!C0:2?;F86*-5H92#E<.@9G1H6'F79+FCEF$A564>69FH(=5,2A$-H$=/8!<!8,'+.=BGF2G'/GF#6,BE0/):C=."07(7FC!B):58(-C0E?<9#50(%(5C(9%B"@3C+)<@5B
@r878
ATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGNGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTNAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGNGACTTAAANGCATATGGTGTTGTGTGTGAGTTCGACTNGAATNATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCNTACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAACTTACGTGACGNATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATTGATCAAACACTTATGGCTA
+
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
@r879
GTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAG
+
'*48A4%8-D?=A.>@(-+4/7#*?(8@/*@C%-6H:;5-9$,6G#-":"E<!/"*B/9D<107'8
@r880
TCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGNCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCNGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCANTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTC
+
:;;#5>'9-A?*20+2&#<:>2F*"AFC@A><3C+".05G%040,%@%:<!#<89&GHG1#E"?36-5A)'E"64A"),/,."#%#+DE&6%2$1D'D?(&#;7>:BH@9?1GF"(,0@&=3H>1-FB&0%=,<+G(E8)5-7E@=%5#/8(;-@%*B'895=B3//#!H
@r881
TTGCCGCTGGTCGTCGTCGGTTGCACATCAAACCAGTCTG
+
D,<D4,!GE9%767B57'3#%D19,(A;>44>5."<:9$E
@r882
CGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTNGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCAGCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTANACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCNACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCANCNCCCCCACACTGTCCGTCAGCTCATATCGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGAACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAA
+
.-?AHG!F0@:!H,F,)62:/@F(E=?'F)74A8-"G5C=$$!>0.#@;E*1=E=6?></<D57F6D?>;B.75:.:7'29D#,2A,!+<=+=E=7(7?B?@&*5-*8A&-!H*"3C@,<3A%3A2+3*:%(!%=.9C?0>2A2/C)!:*+#>'H837$:DD(AB,7@%C$=B2"0>F5"$(3(&0+9>.>#9DC1"*'.#.!4?B;H$(F'$$$5>/D&0<-'*8!A7B@'H6&08=HG-!#9FBC:9(9!1-)>/&GH7C-*#927-G?6&:"B6-%A>!+HA3#:?%'$H4@6!,7G8'DF1%42:=#,2&)-D09=>B@A9/2(.G7C+2@@-10C>=:-GG?>A(2$/G1G>-8E$(>F(3:BE13)604+11.20FH&6+D/C+D003?6*=,<@?:G-C>"!E;#2&/9#:#B6!28).C1$?GHED*A"A7E5G&E,G(/9)@5G--1HD-?2>903@F*B7>8"192C.30:BA1=5!!//G='H*)&B<0@)!4$">-=C91H9F)-=%9F5*H7A==.8'=D+34F%=0HD$?A@!*G;#B&@G+>19F;52;$+6C*%2E%%6CE='=!:$>H0@3"B492:&0@G'8F/%=-35@5#!.67&)H#-A>.+*:(4315:B4"-<)23@0,!D!F,!"BGG68$);-./*)1G-C3$CD6=3-A-6B=1156=4*$150?32&@4;/@3&$:'A+=C9&/);"/C=3?<#B<+140@4=@G5+(HH9$61,09=<+<2D1<1-*0&@>=#$C5G5'+E0%B*=D(B#'2$.@@2/?F%=0<,>@59$B4!>)9E=8F?G/9.$();8")$B)&D3*$+&G7G2G,(:!3@!5+4A:.G+F
@r883
TCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTNGCAGGCGGGCAAAGTCCGTGGCTGATCCTTCNGCAACAGGGGGGGCAGGTGAAGGACTCCTCCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCG
+
E,#0&4F0<E>H);37<&72.>G,!H;0<AC667.<:=C5C,#(>D9EC-&H39B)=D&/&7$=A+!&D>GGF)34&2"3+8&(:=144%-35?2HCF-%4>6$!7B=<F2'-A0$$A%#C<B*GA@,+'6*<3)A8B>8>@(C(&(3-4+E.BG5+6B*#!B:A0@GHAG=.*@B1."E3<,HB/5$E9D)'//!A48F8?A::#9&301/5
@r884
ATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGANCGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGA
+
8-6:+93=>D96$F4,"4>A--41+3-&B)G".#2282F5,$>?:;1G&CE0$#"?0-$&+@1#&2&D/!'1)"#>>6;-B40(;1F2F@%&/&39.7$4C>162G'B?E!!-C92<=>*&90B0*$&'?5#!4;F8"3E139&?6(/%CA8B0+0&5C4E5&0,/:.:8,2)-G=+/70(B/":A&G22+=E/3&8,2!&"<D=0&'.#?EA6-,89?2;:-/:)04;H-=$3"0D,6/,.8#B'2/(?<@<=..>,<&C$C<
@r885
ANATACNTATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACNG
+
$&)$&'$'+++(+$+'#(#"%*%)&'!%#%+#&''+(+'&'&%)&!!&$)#%***#*&)!)"*+%#))#$**+#+)+'"+#*!(+'&'*)#$!"*&#"+")"')+*)%&$&&%!%+'$$#*('
@r886
TATCACAANACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTNCNGATTTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTT
+
G?;G4!+3*?%F59E3-(;G*+/D@0H+*8*A2@3"-&'&.@4.*=0BBG$C?"">@/7;!>244"(&-/<3B/$%<526%E71A!5:?G"5D=953H;HA>#7G-00-G5=?.0$#-#>5*.8*@C<G.E97E/@1$DH&<B<0'D*6*"%4.6&2$7%D%B=($,,?G%B$F$;6(>))3@H!)=B#,0C=#F762A/
@r887
NAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTANTAAGGTTGTAGGCTCAAGAGGGTNTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAANATTTATCTGCATCATACCTTCCGNGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGNGGTAGTTTTTTCATTGTGCTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAA
+
%5@96&%"22%.*#E!.4G4*H4&A'8E!;?0<C?+$<>+#@%6>#%+%@H,!3).@.-E*C''8%D5CC-GE58G995$3424&(*,'@5G5HF0@""%=/(@%$?.0<%*H%':!D$C)FD@B(#284<=/1*?,.==C8D*A,80:GDH"E0H(F6:+"32@B.3CH2.!+488'D777G2H7&36</3D-=D'C6G.*'G(4!(A<6)4&C-+);G:4G"H)-HAH#0:"23@*5,)!A9*A+AF&9B21.D,BG:B7!485>H)=?=9"?*0)!;+>B7
@r888
GTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCAGTT
+
9D:D?401)+=('C8?7.=C$$<&>F/*<'5&)8$DH/B&GG
@r889
TAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCNTGCATTAGGAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGNTACAATGTTTTATGTTANTGNCTTTGATGAGCATGGTGAANAATGCGANATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAG
+
#5):;*/G?@15D+*D8'-F<1/@H5)-G<.*C<?!0='A1EABDG64B/5!G0=G4"E?9/&C",9$.4'>H06*=:6$6A)GE!-G8+'AG8F5)'A-A!:?+'GD<#0$#3G)/4%C$))G"11,0G'/6,%#);3;8/+1:A+F3)3@;F&4,%2*GF=8;,603#3B/'%E2HC5&-*"$C$0>D@@.=>B8>A78
@r890
TCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATNACGAANAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTC
+
74H6/;FE9#5G.E2%3%=8"FF):9=6)&--3)=63+=--,>$,(2)1A)"&G5#D(0F>-,6A$5;&531%&%EE!,H7+6!%A(9>7AH,-B26:&.C&?(;4CD?H1!#,!/E"2'+=-=+?C#"G1"F017.8-1*6G<2@
@r891
CNAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGNACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACTGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGNTGCGGCATTTTGTCCGCNCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCACCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACNAGGAAGGGCGCTGGGAAACTCTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGCCGGTTATNCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGNCTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGNTCTCCGCCGTTCCTGGGTGACAAGCGT
+
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
@r892
AAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAACANAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCNTCTCTGGGGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTNGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTAT
+
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
@r893
CCGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAG
+
GA))04,5*,.)&&*?'-<3;F6:8A:4B70C(/(693$8267D=/@$8117<(
@r894
AACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGNAGAAACAGGGTGTGGAAATCACGCTGA
+
C$,+A*75E/715&!"2!//!2)ED7,&7%$*?<C"-25)'2?B*'+F"":838E*4$H-3:&-F<-1;&91B@%2?;(2/9E"%!'%%-8!""!(*!D,;!$/-E)6&:$C6@#F1,D2#6F%"7(/HD1-)&<&!HE75*E:$98<#BB"E9.1"E!D(1.>&5G'68-
@r895
GTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTTCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAAT
+
,;/.&4B(!=)$!>B!478#:?"#?<D".$>.'G:C>0ED5<,.11,=)D!&"%4<->B<@>%-,H,2CB*E*%0/58-'F07+$$7#!))8;,88<('D+'2"C392"C?/8-5?&>B9)@0B-#*87(7-<:E$;836:A:H5?@C/H@FG7/2C!6!<C5)%!,=4>GEB6@=H3FG42-C!&<<#D$>*H)?@C4,<
@r896
CATCGATCAGGNCCNGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTNTAGGGGTNGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACNCTGTTTCTCCGCAGCACCGTAATTACTGTGANCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCANGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCAANCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTT
+
)!#(($')!&&)""'(+*")*"(*"#*#+#$($##"##!#((*'%$+"!#*((!'%&$+$+"(+%%+&*)(#%*)*#!)&(!&#%$'#*!&))$!('%"!!&(+*"*((*"+(*+$+!(%'#*)))'$+%$++$*#%$!!!$'&#'"&#+++%&&&$"%#(%(!#&&#"$+&'(*("#)"#+!+"*$#'$$%#+)+$'#*!&&*!#*!(#$*#!%)(#)''#(+#'))$+##(+$"(#&*$'""'&(+#++#+!#')&&%#")"$*%'(+!)!(**%!!(*!)%)&&&(*)+$("&%(!"%'%*"!$'(+%*)%%+(#%()+#!$(($%%("(#!))*$*%$&$'"%")"+%+!(&*"*")&)#($!)&''"%'&#)""*%"#((("')$&%"
@r897
NCTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTNTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCAAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGNACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGANGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAANCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGNCCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGNTGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGGATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTANCCCNTCACCACGGAGAAAGTCNATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTNATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCAGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCAGCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGANCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGAGAANTGAACGGCACCGGGAAGCGGTTCATCCCCT
+
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
@r898
CGGCTCTANGTGNNCGCGANCTCNACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGCTCG
+
"*$('%*)"#(&!%$*)%'!*%%"&%+)+"%*#"&+)#%$$!!(+!&+#!"("+*'(%*()#)'$*+&")#!#('))$**
@r899
AAGCAGCCAGTGATTAACGTTGCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCANGTACAGCTCTGAACCAGGGAAATGTGATTAATTCCAGGCATTCAANGTTCTCTGCACNACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGANCGCCAACTNCCCAAATATTTCGGATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGA
+
?%)%'F)E!%011>"5*,E"H;$"E=+=2-/HB"EE&((G0?C/$1?D%3@!?<'C.'.,+*:%1C5>/34EF#;/>#F&0/-.D)8.H22<<D,/!,@.E*F<,0-:570+!A8BB-=*+$A9@CF>G>BCA8#?$D7EG"@:-H./31%@*+'B3'B$2D:=2)"'9)*(!E+.(;*?E;/9*>0&0C:'C+#8E?::#*G."61>%"H;8@4H'!('%39&<G+):BH#2,B!")C0=>B@1A%?>++C:%FAC7-(9G2&!.#,##0,&4>A.&$=71+!5?3-.F.1#8'#'?=68%84#:*'#@#%B%6'#A</39A<=E=B%
@r900
NCGGNNNTNAGCCNANTTCTNNAGCGAACGGNCATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCNCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAANTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGC
+
"'&"%"(&!$(')(#%$)&!"!!($$)#*)$"+'$%&&#)$+(%%#'*+$'+&#*$$&*''&'("'#+$(&%$!'((!+(*++%!#'#&$"+%(&%&"')''*&)(!))$%&+!'#"%$)($""")**+$*!+!%#*")'(!+(''"(%&#+%'$*+$
@r901
CGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTCTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATCGAGATTCTGGCCGATACG
+
:@C3!1EG*?/<AC-D%2)-D)H21%.?8F6,=4,4GDC?>999B1$2FEF,"$.BF4B":7#/B7F?A+#54,G+E);''7;A4%22?9/'?FC..29.&A8?9"0)=&11?/CF&
@r902
NCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTNTGTGTTTGTNTTCCTGCCTCNAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCNCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGC
+
!>)7A"F"9G&?0:H4A4<):/5C28A#=$C:E8)<H5;.;,$A#12>)1!,-/AE!C38-2F:'H(@@41%%A))AA:=GA3F49;'D.12)>1B2/D+$?@;=5C5$@6">*>%?/A20568C%$8>>%-,?H3'=E@5C.00)421&-7#47%'.&8D0@?F)$G91H!7)/D/=!A%G8C6G1:2/58A'*.'A;G=)H>*7'(.172/D'2&1=3?-!D8E=@?@'5*=H"5
@r903
AGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGNATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAAT
+
=-A3-<9FCF@<&#CE>>6?=-/%&0E;F(&=F84(D6:7;*"###3"(1;/=*87::7FH49+$9@7G3!!G$6"6+),)D+3E&C45,9FA4'<1>@7F'<7?/E>+EB4.0(..)18.E(%A<%F;-:<2!?A38D:(1(=:23"FH270CF$(2C"-(G>1:G(7>>5*(A93/$?CD-<G,GG.)G842H8"/5+E=A=A"F;D<70"('7!<=1C7&,--@"!!>>9E':C0,5F1&30)6H.(>@B'%A#175>2E2C6('%B4%A6F*%F<C#-+AA@3=9'>$C2F%$B7-3>$H<-3%:<C'A27;,#/A<4#&=..!'!F&A..,4=.-8/E"FF+23.$01:G.'HH*"1':"7;H4:&E9@,D;:0E@->#?4+7*4%'-!*D%22>9/7D$4.A(/4ED<21,@9>
@r904
ATATACCCATANTCTNTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGNCCATCTCTATGAGCTGANAAAGAA
+
++('"*#!*(%!()$&)%)"%#"!+&*)&)$#))+(!'&%+%&+%$$!)+++&#""$'%'!%#(&&*"%%))+%(++(&"+!&%#")!*(!*%"*$')'+%&("'!)##&!#%(+'(+'+&!(+$'!+(#&+)'*#&+((+$"*
@r905
AAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCACATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAANCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGNTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTNCGCATTAAGATGCA
+
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
@r906
GTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGAC
+
F8043?.3&3,@4$B#DE)<8/("%;(F9;E=%DA#375*D@>/"F5A./A+<ADHH(CB84C4;=2.?1H5F"-73%1?CB!(6A>>7>)599:8*.+9EA3(A//-=+-;./B)@%+%HC36+-A&"EA*
@r907
GNAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCNCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGNCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGNAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATNTTTTCNGGTCAGACANGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTNCTGNACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAANTTCTTCCTCTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGNTCGCCAGCAGCGCACTGAGATCCAGCTGCNAGCGGGAAATACTGATGCGCACCGCGGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAA
+
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
@r908
CAACTCCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGNAGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTATTTNGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTNATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAA
+
B(8"2"&"=,*!C<$):?.B"D)6&+=;!/%4EED:@)"6E%&=B?@69?CA16>C!.!.1&$>D)<GE&>G=/AB@4C,:1+2"H!)+:@+$1)=D&B&<791:44H5".("8E4'*8&?D>,1A7(H<7(+/2&#?E;9C.,0/,*;7.*F,,%6@6%."2F"?@4<0-+=3%DCB@5C!,1H6;2C&HC83GH#H@1>'7&36F<*D42;G*%(?#(;/=<8AA3.0@A-&:9?F<.'"??.1E7,7?1F!9-2FC'$+:3&A,%7#21%FG$HE-#!$1$294<8.:H9??&@9%6H%CCB!>?2(?,C*"7EB0A1#="%CHG*4D2"9.;(":+>@/9;;8*2(8DB=4%
@r909
GCCGTTCCCGGCAGCACNAATGCCACAGGTNCANCCCNCGTGGCGTGAAGTGCATCAGTTTGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCNGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGNTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCCTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTNT
+
.>+(:%$12!9::5&H3B&:FG#8B(%F1177<F/AC)F&"4H)+&&9D5D:>1G>E6?84%,0(7@21@1)2B'-02?77'#A);81+<7DD$.F9A&3E32@97*#F2<*F(EE),;8?7+E(12AE'H1-,+5,=&8A@7*"EA!F$H$EA5@#:7&?.5?%2?%H*.7<0C@A4;>&:,B-(4)H42-4>7!H'7H*CE@?6A4$&3":E<0,A57H)A37.$A(&/&<0.)F27G/2G()"E:(!$=08<B;EG8(>E77?8(E!&D6#99AD/C;,))36.(!;,
@r910
NGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCT
+
+'#))&)"*)%!+$&&%'#!%&")!!*!!#+(+"($%)!"'"$#$#'&)$&&
@r911
GGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGNTAACGCCAGNAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAANCATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATG
+
H3%G"->E*=9H;)7#&3AFA9@1.55&,54:&)!<=;@281'3)0D+:EH.5(@:!9E3;*#(31>6,.7CD&.>F4.*B%"E*B1'.1##!$>..2-B2').C*"1"'7CFGAB80?FD':82(D1)!#'H@"*;3$$:.@/*)D79#*D3,#-9052&8..9A+*;-<'=?D<"#+C'A*)!1F=1/0>H%20GD564"*9'-49*66C(@7<4'')/>"D?,)#/)4A"%D4#-&2>5&#?<103=*A!*1DE#C"',12<12/%5=,8)<#")3<F.@)2$A%?E(G6@>=?:F2.'>)A=6<D-)26/12.3(-;#.G!A0DA<;;A<E:)@584?45%2B&5!:'7<G)-,4
@r912
TTTGACCAGAGAACAAGAANAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCNAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAANCATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAAAACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACNCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTNTGTGTTACGAAACGAAGCATTGGCCGTATGTGCGATTCCNGATTAGCTGCCAATGTGCCAATCGCNGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGANAGCAGCAAATCCCCTGTTGGT
+
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
@r913
ACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCNGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCAT
+
644,B+$B=!:<"'1($"*04C-=%-GD@94EE>:('?3D!DA=,,,'<2%65+EG42H-?&#?;%2EA$0#0)G029;G;29AB!)%)!27:4EG89C)A*BH5!*G5C18/<9/?=+$G@G6#-%41G2#5,551080E*<5*,A//,=&,.?9<($'E*+A
@r914
ATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCNCTCGTGACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGG
+
=&'B,8:+):7DH)6(>-0:+&8H2&;,=240;7A:AF*>,HG;DC8,$E0>B41:&3D765<;F@1936?.FG$2,C>A&!%G8EH+7G@%B4=8A22/F9$*">+1!;$F)/@EH*1<=3?:(#8;83>#:3A)C+=:>6B'3/;+7#3H3>0:%52/(=%??9>1;6#3<.&351;&D':61/18&?4;A9F??'2%32GG,,'*)0+&>76H8)*CA02=)+=<B"<<1A9/='#H.$1C*5)E6:4/%:#29=.*'7A9&&3&(1-9.@?FF
@r915
ACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCA
+
C$D46A/+8%7,269"<,?='';+<4H$,F:E*'B<#')';.*:8+&"($/G;>4:.G@)?A++>A!3#230'0DG1A2#((H&:"6>:%%9$$9E?=8A+".2
@r916
GAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCC
+
G,DB:E>*'><;,6$D5HG!7"/,5GD?"5(@8)95&%/!78-=0,)?%E4.?;964'.@0;<#+G0C874E!,+C/98>3=&;8E#!=<5C)5+F((-'3(F%'-9
@r917
GACACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCTGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATANTTAATNCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCTGGAATAACACNATGAAAAAAATGNTACTCGCTACTGCGCTGGCCNTGCTTATTACAGGATGTGCTCAACCGACGTTTACT
+
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
@r918
CGATGCATTCCTAGAGGCAATNGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCNGAGGTAAGGAGCTCATGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGANATCGTAGATGGCTATCTTTATGTCGAGTAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAGACCATAATTGCATCTACTCCTCGCGAACCGCTTTCATCCGGCACATAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTNTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGNCAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAANTGATAAGCAATGCTTTTTTNTAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATACATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCNAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAACCTCGCAATCCAGTGCAAAGCTTTGTGTGNCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATNGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATNCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTANTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGTGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGANTGACTATTCCTTTGTTACAATGTTTTACCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCA
+
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
@r919
CCAGNGCNAGNTCGNATTCTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGGCATAGTTGGCAAAGTACCAGGCNTTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGACNATGTAAGCTGACTTTATGGCCNCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTNCAGTTCAAGGCCGTTGCCGTCA
+
')("'%'#!*!*&%)!)(+(%"*)%(!&$)'%%(("!#'+#("&#%*)(!%$%!"!"'%%)''&'(!!+$($#'!")"*'+)('('(%*((%'"'()$)*'$((!($+&++'#+#*&"$"%'%*#)"(""+&'#'**#'+*'#%#!**$&((!##*'$#"&#$%"!(%')%"**'&##'"%#%''&"'$('#+%'")"$%((%!")$")"*""$*+(&"+#&(!'#"%)!("*%'#)"$$)$$$&!&$'*$)(*!"%"$')'&!%#$+('
@r920
CTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCNGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTTGAGCANGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATNATCGTGTTCGATCCGAAAGNCNGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGNTGTCNCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCNGCGCTTCGGTCAGATCAAAAA
+
875HD=%9D7,$%*:6@739!?E*5@&4</F$8$'&<A>F=592D8%2?2$52?*)!'?3*?-29E64+H:-FF*F-$9D>"3?&A!2;$D+D4+7-&H'5;9CEH&.=*9?;$:07($1(=#(=;-3(/9;F1.3$)/=<=6@D)3D#>&42:(C12E3@)'%,'!>5@:BF"@2/7*05+192?D4(#AB3%@=A:HCDH8$83!)4>+1>$6,/7G*HGE+A:)>;4*230@C%D)<@?#(;!9883DD>2*$5(;9"?D*57--7F%B44CAF/20<BG>+3./F)*9+&9=920=9(.%FE12+1G?+E#=#*E9(=$<A0B8;#2&B8GG<E'C3
@r921
AAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTNCGCCGGACTAAGTAGCAGTCTNGCTTATATAACNAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTCCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATANCGGACTTCAGAAANCCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACC
+
;9"&GAA!.#1FA+'6A&(-91=F>="*!7H32FF3+2<06*'CA%4#1$5,#??1*(?F=:)*964+;:$6>,#)@=*<)*H?D9!,A6!BE#?)CA#+>?/<7:&B76D7?D&(:&>3-CD%&E"C'H-)2C(9G*A182>2$*29):5#?$@-.#G7?.?H'/E/8A'D!!'AB#D=!>@3E."B@?=,503A?@'/4*,><8'@#7#"E+7A5"/765#&+F//GEEA$B26?)9%'==/,1%%C'?%/$@25&<G?"E+4#1547@B50F8#9!C&?,(-94?%6=>0;3@!D4+9=<(,#"65D")$D85%D.+(GA>).:F$9:9>;7(=3=)-56=3#>E>>
@r922
CCATTCCGGCGGGTATAGGTTTTATTGATGNCCTCATCCACACGCAGCAGCGTCTGTTCATCNTAGTGGCNGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTNGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGGAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCNTCACTTCAGCATCTGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGNTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCNGCACCCANGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGAC
+
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
@r923
AAAACAGTACGAGAACGACGCCAGAAGCCTGTTTNAATTCACTTCCGGCGTGAATGTTACTG
+
<?9%?C4(8?B9*A99)8'$.;+.*;#D;85.,E59-86(!!5!D5&3F;6/#@B-H+045F
@r924
CTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGACCAGTACGACGAAAAGGCGCAGGTACAGCAGNTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGNGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCNGTTTGTTGC
+
4EG"F@;7G>=#A&'&3A."A1=7092</CB/"@#F%!%6556'D!3'C0:@)5)70?>C@:$.=#15/=D5GGH0&&8>E?>C4$8*)"EFH#6,*:=+$)-2,,7-F+5$-/?%F%5<;<><:4%F(2E%.,'B#"#?'7"E.-+3>:59=B'',D7F,$H8"1$-&'8DF*:%"<"@G('"92"-,?:80"5H*6C9C=&*E4?."HA16<-)F!G;"11:,(6!2,72;&F/3372;CBD>73+#-EA78F#.'H!G?3$E%+/*:&:=F(!E$&F1A>,C7F(4;;B5F
@r925
GACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCANCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCNTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGG
+
GG#2;?>;794D+?H>.:A!$&=?'C)03F-1@A1D28<B<$3:*CA0B:A'9'<@>4!8&AB&GE8E70:?31549%"F=$B4;-1-(564+0&=8H/7<:D,1+4E"'?*-FD@/#F;&#/+7(=(1##?F0'50+07B>G09G!FF@/?7=&-.)(?#A'$,,=.D(-%:*5&1EB;53"D%,1DD.#D9?%63AD,&>2.'F+@9;1<!47:4;2C9%G#2-$(3!*%/23$*8!E/4*DA4%+)H=D.5A8(2FBG-D8;*F3(3=19$!=30B)-DAC2-<'3-$3A'''#-&F*%04,"):A1.>1AD=()5.,8;E>/$</3@<4$/#FF3)7-2(>9.4D85C16:'&0:'G<.B;?0#$BBA*8H$;1*A#+.#0E"CE9F492'F7&?AD5DF/EC?"+H785%>1>'47$6#$"*-3/4A8H;3&4&&!-5F
@r926
CTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACA
+
G50#'+H%)=F#9F&>+<G14++;6>7!$9C&)$-7#-$0*;;25(H10EC9E5#GD>#C"CC<F=1F<-BA38A#)@"'ED47+)!D?*G*D<14C%+&@05A#=E2:
@r927
GTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTNTGCATATGNATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGANCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCNATCAGAAAAAGGCCATCTNTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGA
+
FB.?4@3)":,7/C2$'AA(4!AH-()/A2H;'3(0:5'550/5B>&5*$300E17>C)>??2"?3F58!A'9&AFH&$&).4E6$+%----9-<9!H=.17,*89>,6*>856/&G%&/#<8199=)"+/E+(!5"-84-'.77%#.D5+D)0HC'<2%98"DH7B4*<7<()@B3&%@G.95(D>,'G,55"3)<7+!*7/*4"A$<3329AA+D1G>,A/@!#";/#AFG18&3*2EE'AHH,*DC02)%%F5?C>"?--2&A*B$94;<F3<E08#E89?+78!@HD$*73-&9$4G>9.+C<42)<H7"<);:>CE.78756#@8F789)0,E@B9EBGH:F70>:%+5H:#<FFF0@"4*!5@&6$9,-#=;+)G<HC-7:,;>-7!-$;$+04B./%&<3
@r928
CAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATNTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGANACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCA
+
"6F2&FH#E5>-G)B$3?D+83@+':F*25634A1:5></<<7<,?)H)A!,=,40492/2?7D.F"+HBF#*+:!ACE<>.HG7.0$F!#1=!"3G2$+>8%#7DG<F!:(:<HBD+/#84@A8!FE=(<H9DHB;9/,%E'4,4G9E))&C&5)9HH>*!9$;)%H1@0H%1>2CE?!='7/B><A>,3B/2=44!?B<-;1+"#EG*H+??B/2E=9;8;$<?)9&9DE4+7E%D6!/$HC)&6F<6CH$*D:3D=8@6B48=/H+8)4-?=G'%)
@r929
ATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTNCATCGTCAGAACTGACACAGGCCGAAGCAGNAAAAGCTCNTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCGGTCGAACAGGGGGATGATGCGTGGCA
+
5E$46>-@;(97E7)!HB7'0G'/4/4,C@384#078>H@*7=!'6<90&"(/='CHC979(*DG6&D#0/3=($F0;&(AB@8=)/H1%7A90B->$(@D3D$6!7(B9F"9*$:6B7;.'?=;>G+64A"".4#55562GH;!1#0'?3-%@A01$8+#>?",3BD<G7E"8.F56<'@8/?#69.2-&#B%5*&
@r930
TCGGGTCTTTTTTCCGGCTCAGTCATCGCCCGAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGACCTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTCCCGGACACAGTTCCGGATGGTCAGCNCGAAGCGCATCAGC
+
B:.%,6E-;+>=:1B7,-:.A9B'+<>EDF-@.=08?*69@F6/:-8<$;4A=398F$4'A'56+#@='F@A)%,:B&)7AA;?F++58.GC"<6H<0@'"2:"6E#%2E,*7.A/78<531$%>GGA>6;2'=E%3H54'3,3-E<B*A&<"1F<A4(<4D%C94G;7?5C;F)(DA@/;-.6.'0@>?;/1."$?*/-6#"%)+58!':AHHFC/698:!5)A>15%(,H875E%36$2F,913D.<A%2?<%/FA:3E$D(=A/D1E)D"<67BAA!-8-;#-H(&4
@r931
GTNTTNTCCNCTNATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTNTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGNGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTNCAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGACTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTGATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGNGGAATCAAGCAGAAGACACTNANAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTNAAGACATCACCACNAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAANGCGGCGTCAGCCAAGTTANTCAGANCAACACTGAGCGATGCATTNCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAANACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGATCAGACTTGCAATGGAACTGGCTGTTGTTACCCGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCCTTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATANATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTNTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACGATGGCATCACAGTATCGTGATGACAGAGGCTGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGNAATGCTTTTTTATAATGCCAANTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACGCACTACGACCTGCATAACCAGTAAGAAGATANCAGTGATGTCAAACGACGCAGCTGACTGCTTTTCTTNCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGANTGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAGCGCTTCATCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATACCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTANCCAAAAGGAAGCAGAAAGCTNAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTNATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTG
+
&)"(!!$'&&&'$'(&+#)""#(%%*(*&)*&+(#)&'!&$&$$(($%+!"#'""'++(#%)&*$&"%#+!!!)(#*"**%!$*)&!)%%+'+%#!'&*!$$)%%*%)++&"!(&*$&"('$)%&!*&("("""'!!#&*#(**!&!++$+!#!'!(("%"+&'(+'!$)%#%("*$!*('%'!%*"$%#"%*!&'+)(*%#'*"+*%(+!!+"&&(%')''")%$+%(*(")+'$%##$($"$$#!$&+#('!+&"'%$%!(!'"&+$#)+**((%"&%"($)&$&#$!!+#!$''$&%"$*&"$'%$%+#(($&!'%%!$"(*(#(#'%!%+*&'"($*&!")$"+(')!!%*(*#%&)'&#$!!%$("&(("&(&"$!+%%+*'$$$"++)+%"("&*&((!+%$#+!$+%)("'"'''&#%!!*"%!%$!#**'(!(##(##(''&!"+$&$*'#!""&%%"&!#)!"&%$(*"&$"'+!(&!#(&''!&+%$*(''*)*'*+!&&#'&()%(('!$&"**($(*!()'#%#+#%$!&##($+&%('+)"$%%)#(!(!!%&&#"+$*&+''+#&#"$#)"+!#&+(#+*&*+"+'!$+*($+$"%(%!)*$(%(*(+*)$%!#*""&$'##$*&''!"'+%)+&+*#%(*)%%"*%#(%$&(&!*$%)(("!'$+$'&')$%$'*(*"#!*'*#&#!#)"+'!*'**%)%*)+$($')"+#)!+##)!"*(%''$*#*#"'"$%&)#+($&#*(#+'$)+#"#(!$+'#%!(!''('(")$&!#($%$%+'((!%*#'!&#)!)"+!#$'#"%"'!%&)#)%+*!)*&+&#+%$(+#'#%'%"(&#')+(+)$%"&)"''*#''''"'&*$(''*'!(&("&$)!&&*#&!"&)"&)+("!)!"$!$))%(&!(&+%!$%"!&()+"+)#%())%$*%)&!"+"$##(!&"!(!$''((%)*(#$'+#&#$!$*+"$'(*&+&()+!#'$%''""%#"*&+&+!*+'(!"%%&%""!)**'")*#&))+%%)(*&$%"*#*#$)!'$+(#"')&!*)&$("#'#$%$)((*#!!)&'+#$!+**%%!#!#%%&%(+)$%"+'%&&%$!**)#'*)""'$*!$((&*)*+%***'"'"*&&"%*&(%!+&#(+#*"#%$'(*"*&!#*)+*'"++(##!)&*'''#*$+''"!#*''%$*)")#$!&)*(!$#$&)!++*!"'$'+"(+%$#*#!")($&%*%+)"!*+%'$+!&%*%(++"#&)"$)'++'!+!+)"*'*#+!(!$""#+%"&!$)+#$#+#((")!%(#""(*!*)#(&+!)$$##!*!'&((*%##+%)'""(*'"(($"!))()#'$+%%%&(%$'*+($)(++!("'"*+#&&+%&)+$"&)**'*(&$#)$#%%!$%%*#()#&&#%"''*)&'('+%*"')$#*%&*++(''!!$"%!%!!&!)!'$)()!#*)*("&')&*&'$%%(*$%#&&'$'+)*%&*%###)")"*+%'$"'''!$+''#!$*)&+**'#'+!+!)"''%'+)+#&+)#%&#!%*"()!*$!%"('(&#*"&("#+#+$$+$*('#(+'+&)+%%$#'#!")&)*'''#++++'"%+&*&('$$(#&!#%*"!+%($$+&!$$%'*+'(!"(%+!%()&%%''$*#)%&'*%#!$"&+'##''(""+'$&%$"+++#)%(&%")%))+#)'"#*%#''+%))%(++%$+)!$'#"#)++'&%(")(!!)%($()!#)&!+$'(""%*%#&'#*%+)&%$)$+)**%('*!(!$+("$%"*"+%&+"$!!$&+)#$(()(''&'&*%'#+*&'!+%("%(#&))%%+)*''**"**+((*+"*"'%'*)&)(#!(*)"$%%##&+(!&#($"$%('%##%($")"%''&'$+#&%$+!#'!#&++"!")#(*
@r932
CAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGA
+
:F95$?&($)4=<5.FH)DAC:'C+&&!4'5/?#24:%%$#.;<903"6-+;EF,#;20?E"?<%&2@;<@(
@r933
NGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAATTAAGGATTAATTATCAGGAGTAATTANGCGGAACAGAATCATGCCTGGTGNTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCNTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGCATATGACATCGGTCGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTAGTGCTTCTTTNCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAAGTATNTAATTTGACC
+
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
@r934
NCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCTCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCT
+
".7:/0!5G(89,'#@6==.@=?1!!%*#E1<;?,/0C,->4/B"47/8*B2D#G?(154?9E6:",9)!:B673H-9'G,5<3E))H;8;3BE-,:E?#*;'>1&,;G')$$H1@*%.C6*'8&1H8F5392:$H3(?11:E=$%7'3.0F<E;GE$A3/!HC,"6*"!A@'*7#FG7HH:12=D2>'H%+F&$,7'=.B+=A8CA-%6'=9!2,616)>B73+>F!3B3!@"D0C.=$BB3B<>+@3$//1=3<>(3'0-C>?(4'H=B@.>E%/$<;%@5=D/!A-E<F)D=C0=9<$=4A=-D++F3
@r935
TGCGTGACATAANACCGGTATGGGCGCTTGCCATCGACATGAACTGCAGTGCAGGNCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGNTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCNCAGAAGGTGTNGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCC
+
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
@r936
AAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAG
+
H2B$04)="+&A'*>=F=)')%:*$F257&1;<%6GA;'HB<0$%?AA612B(2;==H%3C-(%#H4&$#G6<$6/4@--D$+<E>A=>%-/<-B'8A):0-:1H.28*49-(6'F/,51B$<C#1=41#7C;78&AE-70(4-;"*#@+4G>1@&3,ED7*1'*5E9="EB7G.A9D<#4%54A)1<<4")?!?">0#+>B/-2'./>,G?0G/,/-!$1#'6
@r937
CNGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATNTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATG
+
%!96?8B+,3%&3.;E4//?2:6G*??D8E9'/2$$89.7:@D$%<*-.7<A1"%,+5AFF6'%=-#F56(;C,2.#)(/GDH;=$BB+=."@D1'4&=!9-@,#8A;GHF=G02A3@+=%-H9%<A4D,.6B!:G1-3C6D$GA1F8?FB4D5)AG6,C)$BDBG;7":/!8D'2;=-032"(7='..*A6*@',?<;:;:7D?4F;D,B,$F:G,1D>>)E5.@:01"#B9B.*(/;.("?:9D<89BG=.;9-56,";-D,5FH/!))F5(-B'7F
@r938
TTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCATTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTNGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTNACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTAT
+
7!900&.3#,+5<:")D!F)+02.,37*'EC:1=22<4!$;:#'#F%?</:7(%$/H,.!3<B%.#)BD+&01=:.=@E6*E'9FH=(A"GEHF<*<-9%45(,140,)EE&(,H+)$D&'F<>BHD'EAB+.(@-(>9"41689A?EH%H5-B54*H60:?=$+#23+-:)$#!-3?'7@")9+A6B#3>GB%8(62&&C8;%<'@3+616:B";9%:4GB+!?!/<*C@6;=(2(",ABD6723/A&*1>$9.#&/.8#7*'8D!G"A"@6214#=$,)$>H6.8H">1!*G/AA4GG&?2(/E5*;8-/"90:2,'8AA=%GC?;<&!:D27#7A04?2'8C++@5E'G!?>7D=/>BF.(C=G-*AE7=2A?B!A*9$!,+.'"H4A:/+:G?#(,+5+'>$;2A)"-5!(6HEA'6?8:$B0&B:4(,#7$4F1@EG5+>!$=+'4
@r939
CTGNATANCAGGNANGNGCATNGAGTCGATANGCGTTAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTT
+
%(%!)!'")**%%%#"!'$#"'('%)((()'$!(*&+)!#!*)"$')$"($'(("$)"$#"#+)*%$")(&%*#$$
@r940
GCTATTACTANTNAATTCAGGACAGANAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATNACGCCTGTACGCATNTGGTGATCCGGTTCTGCTTCCGGTNTTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGNCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGNTATGCAGNCTCTAACTATTNCCTGCGAACTGTTTCGGGATTGNATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTGCCAGANGATACGTCGAAGTGACCAACTAGGCGNAATCGGTAGTAAGCGCCCCCTCTTTTC
+
!+!!+**$''&+!(*"(')%&'*"(#("+!$(&&$+$$+)%**(&(**&)+('&""(*+!%)&%)!**&*))+$&&(&***$&$%*!%++%&&*%"(%)"$+!$")!$%#&!(*''$&$""!((+)#*'$#)*+#$'("$(!#'+#(%'&)$*%"$#&++'!#)+%$*$&'$#($()#(#"&#'%'*$'*!##)&"'&"!+!!&!*'"'$'#&%'+*$*($+#&%%)!(('%&+#$"+)&$+#*!!$*$!(#"((&("'"++(&()!&"+($)"%))%%+("")'(&)"((+"')))"$"'!!)!+&'!')+!++*#%#$$*&(!%%'&!*)(%%+!!)%#"$$$&*#"%%!)#$!!))("&
@r941
TCGGTGTGAACAGTGCACCATGCAACATGAATAACAGTGGGTTANCCAAAAGGAAGCAGAANGCTAAATANGGAA
+
&#%!'"&"'(%+(!+"$#(&(%+#%!#"+#!$)#&$$)+&!+&!(*$*$#$!!$'"*(('!'!$+&)!*#"!$%#
@r942
CAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGG
+
C-.A9%)$9,-:C=&%&=>+/56=3&6$:?%2&>.AG49EC$?,8'+$/12(-EE4&?937&99H"*-4*#H*<#E987.3)0A0"=B0/+)E'DA#,7G,"EDD0=97&G>%(G:4H0,<),$!(<('2G883!$:,1;>/":E5F(:--15@+(1C$#7/:0"&/8:DA219F,>F783/25,@&9?;&',!?>
@r943
GGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTC
+
7>"/7&0@*7+!0*,!,%&&&FG@':61;';5%@$5&07@?/&,=A;''3>,?!62E:3?$=7'?ECF-:3+7&>8*B?B3=0@E3;,.,FD&6"A*%)69,6D22&5:84;B<BA=29.%BB/.4*:!3B
@r944
TCTCCCAGCCGTTGNTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGNCGCTGAAGCTGTAGCGGAACGGCGCGCCATTATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCNGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACANGTGATGCGCGGCTCCGTGCNGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGNCGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTNCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGTGTCCACCTGCAGGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGNTGTATCTGAACAAGCAGGCGGACTTCCCACGNATTCCTGTCACCCTTTGAGGTGGTNTCCACCAGTGCCTGTACACCGAAGGTAANGCGCAGACGGTCGATGTTTGCAGACNTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCNGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTGCTTCGCNTCGCGC
+
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
@r945
TTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCNTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTNAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTNCTATTCACTGAGAGCATTCAGAACACTA
+
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
@r946
CTCAACAGAAGATGNTTTGTGCATACAGCCCCTCGTCTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAANAGAAAGGCCGGGAAATANCCAGCC
+
;+BH-;%?5>9*D+/:B.%8>D,@H?E.27;+GB$>(>B?*13%(!A2DGH;FF4>8*4/27@>145:*:.#>G=F3?B!"C*@>(<!/3?@G$!A-9A&,.C8#,%!/=024
@r947
GCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCNTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCNCCATAATGCGGCTGTTTTCGGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACNTCAGCCTNCGAAGCAGTGGCTGAAACAGTTGTTNAATGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGNGCATCACGCATGAAGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAAT
+
+&*$!+)&*)%'$'!%'#%+$)*"#!"**!*!'(%)((#$+*%$&)''$!%&+'%!(#&*!$"*%((*"&!'!!+(#+($)(!)&!&!"("!$$!""#+&(&'&')+++(!'"'+*"#)"""$!++)%*$((''(#!!&!!")"+%+)+&$"$'%%#&%$&(!"#%)*)%(%&$$%*!%%'&"%%)*#*"'&+"(!!+""%)(*""&!!$""*#("$"$&'(**!)%$%*+$&*)#%%!*(%'"%"+$!"$'#%"+&$*+)$#")#*+"+(#%$(#+'($"'#)*"(!*+')!#+%&#%$*((###$'!&$')&"(&)'%'!)&&"$"$)'&%&$!#%!$&(*!*!#((+"*)#(%%*##'+!+!
@r948
NCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGNTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGA
+
*#))+!(#!#)(&"$)#)'%#"'&'')("'*)+!$"!()$#*!#+&+!)##('(%*"*%#%)"*#*%%(""(%&!&%'*+('%$#)%&%*&(#$$*&'!)(!)"(("($!*&&+(!$"#!%)%*+#(#%'#!##$(%&&(*#(#!%(#"+"&)#&#')*('!+&(('(*%"!$%!$$+"%!(%!&&+&*
@r949
TATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATG
+
'H$,-8H&=#86>10E0FB.%26F*8:;E49=%$.)*!$.G2F7><'?<.0*G:)#>'9979H+A((<5A#.=&$FBE'-&C><<H9?E,>BB>&BFE.,<1#0D4>G@8>9.1,'$5
@r950
TATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCNAGAATTTCTTTTTNGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGCTAAGCCATCAATCATCATTTGCTCATGG
+
#<:1/);:"C3D#7F#5G!$(1#D*:>@<,"16CC,83'B2FH#%&(*8&0."$1(%@(G1/&>(=68<+-D=79$D*)B/0C2<G#<>F%)%A!!66?$+,(BF,?)(!!E<:5$A0$82GB8*)970)8!CD+*H%,;?DC(/:9:G<'88"<%&A;5<57,72H.EGE;61*.6GF5
@r951
CCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCT
+
2%?(?:)%,?<$7/C2(E.0;)9-FA<D;<C6=.'<!@?024H8+@<":BH'1C+0HD6?F+:2)!9>)2%%7,<5'E@*1G22)
@r952
GGTNGGNTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACANATTNATCCGGCAGCGTCCGTCGTTGTTGATAATGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGNCCGCCGGAACCGGTGGGCTTTTTTGNGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGNTACAGAACTGCACCATTCAG
+
"#!')(%%&#'+!%+&'(**++%'%)()&'+"+')&&)%$&!#()*!)$$'"*&)*#!#**++'%)##%(%**(%)"!+"!)%$*+#'+"!*('&#%''%+'$""+!)($*#'(")'!$#(("$)%!+"#"%%"#")(+&&+)))%!"#*#!&#+*&!(%!&("*)&+'!(("'(!*!"%%")(+!*!%(&")%"#*+&*)()+&$"$+'(+)*+'*'%#"*%$$!$#!)'+$*!#!&#&&***%*(&+'**%)##)!%&!$"!$'!#%$'"'&((*"$&!'&'('+&"$$+$%*!&#++%%)%!!%*+*+"*+)'*'!$#*(
@r953
TTANAANNNTNANGNATGAGTTTCTNTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTANCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCNGTTCGCCGGGCATNCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGNAATTTGCATATACCCATTGCTCACGNAAAAAANTNTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCNTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGCTCTNTNTTTTTTGTCTGTCCTATATCACCACAAAATGGAGATTTTTCACCTGATGAAACAAGCATGTCATCGTAAT
+
#'*$&%"$&)#*&)#++%*$''&+(*"$)%$!)+*&!*''""&#!"'"#!'&*!#$&)$&+%"#+!%"$)*##+&++"++!)#$)"!&*+'+#*"(!"+%#($%'+('*''"*('&%)%!(%%)'($)"$$*&$%#'*'*&')#((!***)($"#("($#+*'++**&)'**&)##$$*###&!(+'#)%!)&&$)+&##"%%(+"'"')!'%"'"")'(+*$##%)%!&((""(!%$"'&"++#))"#*&&###"&!#)'+*+'***&%((!$'+&''%)#'!""!)"!&*!)+"*+#*&+(+'!'&#%+"$$')'*!&$('"(&&()'!'!*+&'%%!)!''#&)#(+&#$"%($#)*($())$%(%'"((%#'#%+)%)!%$%*'(&%*#!&$"!"##*$)(%"$(!(''(!&)$(+!)#+'&!%$""%&%))&!"('"&($()
@r954
GAAGCCATCACCCCCACACTGTCCGTCAGCTCATNACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCNACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACATATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTNACACACTCAGACCACGCGGATGCCCAGCGCCTGTTTCTTAATNACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGANCACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCNGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGC
+
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
@r955
TGTGTTNTACANTATTATGTAGNCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTTAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGNTCACTATCAGTCAAAATAAAATCATNATTTGATTTCAATTTTGTCCCACTCCCTNCCTNTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATNCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCT
+
(%)+'%"**&&+"*%(*!$'%*(")%!%'#*#*"#*(%+#*$+""*'""('")$$$(%(*&)"*$%%!(")%$'&$))'*!)!&'"'*)&!&%%%(!!"'($'*(*%"#$+$)$'"*$+'!))"(++')#)%(&&)(+$#$!+(%+*!"('($$!'&'#$$(!(""#)%'$+!#!!!'$*%+%(*!*+#$+%!'!#"!(*$+%&!'&"&#&#(!$"&(%&)'+$))+"*'""+'*('%'*""%)*%!'$#$"%$(+)&*+%!)&!(&)"%%+!'+)+!+)')$%'!)%!$$)+'!)$#!$)**"&$'(#)&((#%#'$'&"*+#(!"#+'$$%&$+""*($$#&$+*+&(%#%'
@r956
TTACANATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACG
+
+H":%5-+<4%H&3A)B7!,<:(36%D"$<+.">0?42%G>4(,AF.&@3G7195?33(9.*AH("5G@-20'"-<>D+C67!7)<&"F;1,A.B70
@r957
TTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGATGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGNCAGAGAGATTGATGTATNAGCAGAGTCACCGCGATTATCTCCGCTCTGGNTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGATAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTNAAGCCACCACCGCCTNCNGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCA
+
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
@r958
AAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGANCGNTGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCANTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGACTTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCANAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAAC
+
+($&+&+)($(%$%)##''&"+$#'(#+##+%))*&#+%'+!!%$)*!!*++&$+!#(!')$$$*$%+##$$$"+%""$*#)'*%(#*%)+%!"#&*(&)#%"&'+%#&('"!+&#$'$+&$%(#"+$!$&!"'(&)"*)#"("#)+'!&)*!#&'##!*"$$+)+"+"'+$$)'&+)$*'*)+$)$#('$%()"+#!(*"&&*)!)#!))"(&#%+")#""$#&"$%+)$$)%(%*#*')+(+!$*%#'&)))&'!'%('$#*'!(#$&+&%%(*!%")$+"(!*()$('&+!&!%'#$))'*#($$#$'%'+$&"%*'++'#"+##'&+!$*(%%#"%+'''$%+$!''(*&&)#&+#$*++$&#"(#((&))&!"#+'++***(*'))%%"(#()&)"%)**##'"&+##!$*&&((**%)(("))+$())")##)!&+"'$%'#'*'"""+#+(%)(($'#*("#*)#"&)$*$!*$#%$%$&"("$'(#+)!!"%'+$&+*'(%('+(''$(*(')%%*)')&"'(&')*()%&&'#%%&*)"('$+'#%%(#"$$)')%(&"('*
@r959
ATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGNATTTCATGGAAAATAGTTAGAGAAAACGACGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCTTAGAACTTCCATTATTCTCCTGAAGNTAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGC
+
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
@r960
GCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTNAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGNCGGCGTCACAGGTTGCCCGNGAGACAAAGGTACGCCG
+
E+E;62B/FG*GH%0%$A2/41=A9!H:AD9%A?+B+"60A>=?:#.4G7*0=@1/6GGE"E29691.56;/*"*1'7/D=-+6&-C/'$0#;*%(:&;7#484(*:'.56GH>HDB?/&3>42C@D!$::1?2!;E?+$:'AD?45A(A0"@,>5>E>FG+<2:CHA.A"!A6AB7$EG52!?35H(G0
@r961
GCAGNCCTTTTTATTTGGGGGAGAGGNAAGTCATGAAAAAACTAACCTTTGAAATTCGANCTCCAGCACAACAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCANGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCACTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCA
+
'5.5A75E9#A:#&2?F$?D!<C%8,A8C.(D98/=#BA.DG&F2A923GG&->(=)<8DF*;!%55<DE6)C0"3#.6!")(G<1B(HE;(9C48#$FB<>-:+?-E&2-C'%?1.>#2>'#-(>:1=?*E*%*)H9G8B%0&@D&755,6)F8G0D;$+3-G*&,2/9#7;F91G4';,:&34+3+0B:E;"!CFD9B1,E?&'>>+6<*7))0H9;.#61(+(EF%C32$+"+=7.6>5)3?<#=1G%8'5H=5<=3HAE>9'///BEA6-::;0$B*19=<4#G68D$@3.)?,."HA:*%A3EG.2?,$=6-21)-/!H!+6#*9,H:
@r962
TTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGNGCAGNGACTCTGCGCTGGATCGTCTGATGAAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAAC
+
!%;9C.:70;@:()="C7BF"=>D2"37D6-!"$D24:G$<:)B*=A5G<*"AC+*4(44!>F439+A8()(=F@=:,/0H,,@<#A2)E*,A2+%=BF4!@"A'!88"2@+5$+#%G)@+(#.%16&'GC:E$06D'"%3E0E<$8:>5)FA1$+DHE%B+A+4F@+*-9+>:&:3$5A?7D(#!F,#)499E(,3+*-;?#%%")D/GC
@r963
CTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGNCTCTGCTAACACGTTGCTCATAGGAGATATNGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACCAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATA
+
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
@r964
ATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAATCGGGAGCAGTGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGNCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAANGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCNCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCNGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCT
+
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
@r965
CNTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTNGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCATACTTTGTGCCACGCATCATCCCCCTGTTCGACNGCTCTCACATCGATCCCGGTACGCTGCAGGATAACGTCCGGTGTCATGCTGCCACCTTCTGCTNTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACAGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGANANATCTGGGAACAGAGCGGCAATAAGTCGTCATCCNATGTTTTATCCNGGGCGATCAGCAGAGTGTTANTCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCNGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTAT
+
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
@r966
CGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGT
+
>26E,.#,AF3HF'&E##CB=-!$+?%5A6#+6=.G%-)":%;BA0>@3?$7@;E#E2B30?@;%*(=,)4E"/0)C7#'(2G!&!%*F$>
@r967
NNACACNANTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGNGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCG
+
$#"%*"'$&%**)+(%!%!#&'&"'!#("+**&!''##)&(%)%$'!%#"&+!(#'&&&))&*((&(#'#$+(#*+*((")#)*!##(*(%')($&+'!""!(!+%!#**)*"'%"$(%#&)##*$)(!!(*)&"&%###*(&+%!*$)%*'#")&#++&((%$%"+!%!$*$($#))!$)()(((##"'+"*%#&%"!$!*)"'&&&#&)&+#&!"*!"++&'!)+&($!+"%!!$"("!(#++""&"('#&))&$!'*&"+
@r968
CGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGANCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGC
+
/(/A"=#%;152;3)=3"<5?!B<+D</F"<>;F.3;;B.*9#$(>@:11.;(+;'6H+<.G#;(F4GCA3-:+%&&%(/+C#*,#2%A1;'HA14/A2%(6$$.+'@'!>:GC#$,B@"+$6>@7):"/G@#5#';@+"0()D0C<--+H>A0'"CD915#"?(F,H592::/3!.9
@r969
AAAGCAGAAGCAGATNAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGACAGCGGCCTTCATATTNTGTGTGCTTATGCTTGCCGACATGGGACTTGTTNAATGAC
+
7!=6DF+AG:+%A6)7!D&7+(7=86%EC?,93<:.@(G*4"9($("GH)%E,407(,15<,)%9=7E7?'-0%G*,4CC.@<(D<@0&!D>,9/@90*+GA??+76!E#/&!8
@r970
GCTAACTTTGAGAATTTNTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTGAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACANCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTNTATGGAACAACGCATA
+
,B7>1F,$%C;>A:F%H?%"(CG.<>%-*6=%;$"4&93G!,+$8-G!<&'-:#0"6D7F&$<3<$*&)2H?CD,=&!(7?*="'-:D$<!13-('>&">='"'8185'"3.'267B./=()/$'(:@B'G0@%F@7,5G.9A93?-:&60?-62&6B=A',-,9%D6,?5@<2>1*)%,.(#>BH%G:F-);%7;F$&-#',>A!9(<G3?A)<15#7%,F<-=?9@:.7:>6C1)HC39,/G6,B*42/=G<B.>*,FE223<1'-7!.B8;FG7:*;7H4A,?G"?<@69H>%#H*'?A9%4.$G>E*5$E'G+%40,(%+"D:&A/2%'7
@r971
GGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCNCCCACCGACCATCTATGACTGTACGCCACTGTCCNTAGGACTGCTATGTGCCNGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTANTCGTTCACTTCCGNTAAGCGTCGTAATTTTCTATCTTTCATCANNTTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCNAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTNTATTACCTTATAACTTTTACGAAAGNGTTTCTTTGAGAAATCACTTCACTCAAGTGGTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGC
+
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
@r972
GAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGC
+
BA<:(.0AF1'"(4D*1)90'!/%A'2F)%!1=06;+3>>!+<7:-52+!?@
@r973
CAGTTACTGGCAACTTTCCCAGGGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATC
+
:A?-'-6/0'9&H!D-$%&EC+1<FH.3."E%29A8*/3B?3F8.-1G(00(81C231((AA-";(/7472=AE05088$3(%390%",D"5"07-E-+%&D
@r974
TCGACGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCANAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGNCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTCTCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGAACCAGTACGCGCCCCCCGCTGACGGTTTCTAACCTGTACGGTATGGTCACCG
+
.$.&<95B<@8F"3821B;)-:G%?E4?#='"E@1860!0478,1?H403E99(7E/F);3+<B=%'3AG&&BE6,612=31G"8"1+,D6(41?%6#HGH=">+A<>"=G:=A$"*89H6B?%7!2)$.G;#@B)1+..@#%,:GF=*(8+<64F@-4@BD5,(9!@E:B>9$E$99$9#4*,<1##@:37(@5!"0"<9G&0DD-@50(2*0<3@85)*440:.'71.C;##6%2%,EG?5AH5$&0#H9,5!1).6H8E5$&<97-&:69;CB@/<2!F>1=#4/A?CH@55A&.=/AD)/+6F;2C%%)!;%%5:@$5/C335G!&
@r975
CGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACNGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTNCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACNTCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTNTCTGTTCAGGGGCATTATTCACCACAAACNCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCTTCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGNCGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCA
+
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
@r976
CCGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTNGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACANTGATGA
+
8B>8:23,$2#F?-2;H$C/"H!+#$%/),/!*:-;D<#/+BE:BHC$D,0?)&7DA+,6")FB,A;C49*,$60<&8H7!>"4507<!202H'B'#A44F-#><%+4-3&$);2+B<"><>=*HEG9&EE6B($')#@9&D;05B-D/6
@r977
TTCAGGAATATGGTGCAGCAGCTAGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTNTGCCGCTGACAACGGCACCTGATACANCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATTAAAGTNCGGCATCTCAATCCCCGCCAGATGATAAGCANCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCNGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCC
+
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
@r978
CATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCNGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGNAACACCGTCAGGAACACGGCTCACTT
+
2=37H'043:4>3F5H1=:@5"FAD;8#$1(!G6%"6<66)E@C4$F#@/C;F,H9'9=E@-7&G-,41DFC)"9.0E@)&5=?8B4B$$D1,++.0%$$'#;G$7"H@;@7-"&(-1B#=,/A7-H5-@F,0BAF/&@;F
@r979
AAAATGCAATCNCGAAACAGTTCGCAGGTNATAGTTAGTGCCTGCATAACTGTTTCGGTCTATATCTNCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTNCGGCCTTTTACACATCA
+
*:7F3<<"A/2:F)3='</E66>?:';*021.@*1;1%&/H%)0'E&G@)EF..H$H<$*DE563.8G$D+E)#<5%6(*6=F+@4$',:#F;AF6##)*=HAHD);1=.0-075;A0C:;&B$@H60-851%E+2.>@D".0+EA/%%)&.B4)B6=@CH9').=-!8#/85*,=;4'>,-.?$,#G7&2#B'"G1-D0&3=#.(+7852=!$B!H8A80!247-5=,<6FG2C-!B)CF@=2=C?#?A0".>#C9&D8-C,#5FBGE-1-C??A.!9B@%#F>=;+";)#)F@
@r980
AGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAATTTTTTATGTTAAACAATTCCATCCAANTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATTAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAANTATAGATGAAAGACTTCAGGTAATTTGAATTGATTGAAATAATAAT
+
)*%0+D69.+2C!:<1D-H?7GB>@#646D&*<BA6,20;<1CD1*?8%3$E!-;2?>9/F;03?G#48>2H-6)A<33!BH3<D#'0B/2,1;F+&9#*:B/%#7><=!-;".++C9@,(%B<$>?C!(=7%D0(";*F841>>'7%,"G,HF:15&+3=BAF":9C,5;+37$5$)E6F5"AC+2:A-79DH5E@?.)<6832D0>!9'<F/DA7H*E6"F3!.&B5!22A?8'++&7;8G+878"#-28$9$A:;!C!"$@$G4?D)HD587H4!>:E&=7"'3CD.E:>&#!F$8++GC</(54.C9>'G/HD+6H892C$9>)H!:"<G+0E#/D,"-71.59:7F#F5HA
@r981
GANNGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCA
+
''!"+*&$&"'(+*!'*"&!##)*#!*'&'&#!'+&)"'"&'&!%$"$)!!*'&++%(!""$'#+!"+*'%((+!+"%!$!&''"*"%!"#$&$'++)+
@r982
GTTGAGTTAANAACGAGTATCNAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACCGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCNAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGC
+
:7/"B2>!8?4;<><B9->G4>(C.4B)"?@*<.)F.+'336@,@C!@-&=:EDA2'H/0>$;/')H1H.15>/E!9"9(<:+HBB,)EFHG%88(B>EC*F(4/F&:.C2#2E.@)5BE4A=*2)"#/EB0-F6$!0H7G@)21/4+/#30$@#.'#<4+=B<!7*9G9(G:&DA&G(5'279+.EA6A/8)B>!+HB
@r983
NAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCNTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAANTATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCATAATGCGGAAATCACATCGTCACCCGTTGGATTGTTTATTTGTANGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAG
+
#B%'&;&7;/.>"9H23G>4C6-&HH-E36.A>'$&9E;;4//=9#%756EB5EDG<8/!6;8727A;D97BEG67-D+#!8+/HHG!"H:.E@FE/,&<+GB'8C>'7,GC&@1&>A94!1D@5H@('D)(D--:,B/0;*$"6:E-E?+"(C(#)G<04+6.B6*),3(69$E.G&3>)B=0&3=A/-6%B2?)BC8)(<">!,(!1751:7$"=<;'"'B6)+";08"834,(*2EC213-'%>!'&(-69!6FB&>?!EB7.)@@8*8@-$&)E5)()565*G>5D/).985B:H)"EH9*%8/E;0!$-C+4;?81EHDA,!4!)A3G4+EC!E$.=B:1AC9B$.?"&1?8:4G1@7$+3@21==/1=72"@8E2B3*9/)H.;BD:%1:82+7'A:0DH<':0G9/$=;#95B8*;1+7'@&%1(F
@r984
TNCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGATCACG
+
%!F$B5FF(1;E-,=10#&A>52A+05,"-A.*)<@9)97
@r985
TGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTNAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATNGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGNCGTGAAAGAAAANAAGTCAGCNGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCNCACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATGATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTNTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAG
+
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
@r986
GTTNTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTG
+
7E5)=5$"2'96-1B!D2;<&H"&0.$&&5::#?!C5.4;A5(B289*9%32G!(("6<-%9>(G$9=0-B2;1H$C!(*2E'(2<GBA5?:!D3-1A.$(G9-,G//G9D>>D-(:BB&/5:37FG67CC3/2&7&)D!-=>B7G"3,-H;=A.39@&+H!#1+;90B,4;CA*:);.3:2=E4
@r987
AACGATACCGACGCCNGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTGCCNTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGC
+
"$C*"$200)<;((F+/%/.>,8C,5#CG(:'16@<.+)&:H@B!0$83!-78>##A+%1>75(8,BB81A"+:3-B."(A.8F8$,;F"#G+55'BBGF8-#(+FH064)67+D47&3(F4*%*1G:-60>HFG*H'!(>(8CCB**B>?80-49H8.@-#$4.2!"::'=)/9:1(B<F39DD69/$H->*(G;6+-)/5%$&,E%A;7,<4=@8354<!*E4C$=84
@r988
ATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTAGCTCAACATCTTCTNGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGTCCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACT
+
BD1H4C6%5C>-)+5+@>*+F39!*!,0#;H>$G/C<+CF,>4,0FB:7>)"16=8>H:!3)4C!3&GC)5*4BA/,"A$#1C1<@"/#17"#F12(:9AD-,>;/H,?#0B1$-7G;G7@02!87,);E&F298B(B9?@'<9=C8G)4>(5*'.8"B@7%C+E69D$.8<*H$404G02D9/!B.*$,$'4:(5%.'$B,3*0#(1B':-&DB(F0H27;.*-@!/7?!):!D$.A,24(>23<*!F374;*'*@#/88+$=FA&*0E>#(3:!/#&",96H+;42>8=;E/A;#DD-?(FB!525@(5*$1
@r989
CTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAANGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCACCGGTAAAGGTTG
+
,E=(0*)@-D*;9',C(0HHD+)*9!-;"&92>F(*<+4F),/$HH:B#%2'-(B0@)(1)1$F4*=&D!@A-;-?59=6>E58*3?"7'7,&<5AC20G5:<,,$1C$'78"3E9$=%98@FG'=9?.AE/(;<?&5;<@-+%37<(E@1,5648(2<(=H)-@.()GA9!=*!$&?6"1;8CG(E"%9D*$4D$3<;-2?1;B<@9G7,9E04CH.8@/'*A"G=(GH:(D<G/7+B'$*B?-960B(HA,>@@>)'$DHG"-&"3HA8@:?",?';5&35.
@r990
TCGCTTATCAAACGCTTCGCTGCTANAAAAGCCGGAGTAGAAGATGGTAGAAATCAATCATCAACCTAAGGCGTGCCTCGNTAAGCTGGTGTGGTCGGAGG
+
+"($!'$'!)$"!'"+#'+!%'$(%&$!+"$()$!$"&((+#"$'&#+)%"%'))+!%)**!&#&&#'+!%$%'$%#)"(!*&##!%'!#%'#)++"))"'
@r991
NACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGNGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATG
+
!=+;F=$D!H+/<8">>0352A)3&$>#:!%":32&9+516;28AA(D&F-2H$:A*5,C-202C?<A-==&6GG-+@F?8%F=DC=9BC-0;;0+$"+7.8&,?)&*3@4=8+@/F+B%*$#)
@r992
CGGCATCAGGTGCGGTACTTTTGCGNCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCNGCAATTTCACCAATCCAGCNGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAANAAAATCCNTCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAATCGTGAATGAACGAGGCGCGCCCGACGGGTAACTCACGGGGTNTCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCANGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGANAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTAGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTATCATACATAAAATCCTGCAGGTCCCCTGCGTCGNTGTGTCATGCCGGTCTGCACTTCCAGCTCTCCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCAACCTCTCCGGATAAGGCACGGGCGTAATNTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTG
+
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
@r993
ATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAAGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACNCCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGNCGTGTCATATTTCACTTCCGTACCCCGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCNAGCACCGGCGTACTGTTCA
+
-?G0D-$%3A'*HH)E<;B8BBHA!21/0F*F8;38##=<2)#4BH.%49)05@;*.H@H"FE?:B9>"HED!>2'':+1-F:8ED%+-AH'HE,*8!9;*/EA+01G8(FH-E,0,%:@>@*B*E2B8?!HDEEDC$EB(;+)$F?%/0@62,4=?+@'=*F"8,8A0B*7<$B!;:*(08$D?-#,1<44H'(>C/"B*6$!*6(+EF&2%,7<B51C($?D8DABB>F<1@$,+=9-,#,C<)76%1%='*F:#7<!%#,DB+5:;%(@$/8C0,2$55F#>.%%=6?8!+$67E6)->0*<E(C-72<E2!3A,3=!@HH3
@r994
TGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATG
+
D!<FC!!+71G!@>C>?*B*4*<,@E*'F23<$)5%=16/$
@r995
CCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAA
+
&A3((.%("6734+,/7%3.,=<7:A%5H*8@B4D1H$F&2C57>)>?!6*=2;*6"0H,$.$4&EE5C6%,G,?#9"@1A@:(-=H)!'$$/4&1,"3H%#(>$!>F$675-!G&-&("4--&:(E(6D3B.3$1,BH#,E+)01E=G&%5<;3<:9C/9%3,.$#/H!H3:=&)A:7F*6$+4-1+/B%*<7;(2$@F"/%E!("="@;10DA8>5&"1/@#4;.,926=.*/H*.DF7'D0E0/CB8(33B/!:
@r996
GCCCGTGCCATTTTAGCCGCGACCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGNCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCGGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCTAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACNNTTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTAC
+
ED11%&C/0&?8()0=3,A<C36@@9?.%H!DA+18=C?6&82'1+=/H1>5";"-;F)6?!.*<(A/;81."$?:#:8;1"H#29F5*F0+18:&.,%>%:G(B)!5C9"?C-?"7%E:GD,"H!%F1@E@G,G59DA#3*6A=!?/D,5C<'7?&#'&/-(:-6@?88#G+D6@C%#?@08-H;=3CDF@'?H87."=1@@%46=87!2B,?)@&439=D=1-=8(6#3>5&":(1)$-.8!1%+91<4;&$=0GHD-:B>*FC>G532:;/?#16%D#32#,@7@$A,(=9AE&E>"
@r997
CTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTNGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCCTGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATNGTAACCCTTAATTTTATTAAAANCACCGCAATTTATTTGGGGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCAACTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCAGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATANATAGTATCGCCGAACGATTAGCTATTCAGGCTTCTGAAGAAGCGTATCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTNATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTNACTNCAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGNGGAAGTCGTGGAAGAAAAGTAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACNTTGCGCTAATGCTCTGTTACAGGTCACTAATACCNTCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGT
+
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
@r998
GGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAA
+
@D&7G@$:<":-;@1&;+6349BEEFD(1,8753*3<%C"/,21%!#D+$85'E21H%B>16/!EB-)</G?A#2==8F@9C*>#89E#)&/H?1=4*4":'?8B#:">"1C
@r999
AAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCT
+
,(2FG9?:)8<(3,:8,F5#+F75?=$E#A/1*988*-!%04!G!8"H:%F9D,
@r1000
ATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTATNCGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCC
+
/;G,'GE2D@+8E=E@HG0>7@!*C/>F858&52EF'H+3=H0)CC8"<0B4"@-%@3A.!B05&8,!-<3*2/,5.,0C?4#71,#+6##G;B6=@E,(?9,#+.33@-GFC%)D#@F8!$0D./79>9G-)F3,'A#4".6H?7,,72(;<2)"'D=,@8(&!(::)5:<&C:AD&-C&434105))$$9H?2.06G980*3<<.7<$/<'B@3F*A3,90!0
@r1001
TGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCNATTACCCGTNCGTTTGATGACGAT
+
5?DA6@#5':='H3,"D.)2)>$)'B4%106:6;BA=.'8H1"A+?"D%18@D0A@:<112:4H&32($C!1$(H)?"-@=36$&594/!9<;%1+B</F?"H".&+900&95.30/G1("$E"-H2-"&GG6<$C
@r1002
ATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGC
+
+45E"-@E&@DBC!<@:BG;@3C@8AC19??+F/DB/FB,E<<!3"/*EC*<<4AFDH<#A">5?F<->-!+,
@r1003
CTTCTTTCAGACCATCGATGGNCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGT
+
C&:+)!@#&98$C#*DE-'$<41@>3-9'3*HH.5D/F#>19>C>CF,73%G-"F-33H+99.6:#D?;H10DH$?>!7/E0@,2=+="2:(*!"B1/=9/69#-:
@r1004
TTCACAAGCAATGCGCGGTGTGCAACCAGCANAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCA
+
0#@C$9*3+)#!/C<@%/G)-4=E)'4F54)#1-!?*F.H14#,36!0@8;G21<;:&69/7A*<>:G@%$@F,G,+2D03'';HGC50"''&))HB4=97B2D9@8(5(H14@:"E>+!4=?9*BA&'=5A):-:H<36H,9@=">
@r1005
CGCNNNNGCNNCNTGNNNNNCNANNTCAGNNGNNNTCTNGNNCTGNCCTGNTNAAANNANGNCNAANCNCTTNNTGTGNNNGAGCTGTNACANNATNNNGANTAGACNCANAGANCNNNAGGTCNGGTCNCCANGCANANCGNNNNNAATNTNNTNNNNNTNCATNCNTNTGNNNTNNCGNNANCNNTGCCNGATNNNNTGANNNTNTGNCCNTCNNNTTTACTNNAGTANNTGANNCAGNTNNAGCNGNANACTATTGTNCNNCNCNNNNNGCGGNTNGGNACNNAGGNANTNNGNNNGCCNNGTNNNTTNTTNCNNATNNCTNNCGGGNTNCNCGACNNNCNTANANCTNGCCGCCNTCNCTTNNCNNNGTNCNGGCANGNNNTGCNGNGANTNTCCNNNNCNNGNNNTNCGNGNNTNNNNNCGANCNGCTNNNGCNNNNCGNTTNTCCNNCCGNA
+
#$!$!!##""#"!$#!$$##""$#!$$$"$"#!!#!!#$"!!##!!"!!$"$"!"#"$#$#"#"$!$$"!$"!!$#$$"#!##$!"$$!$#$!$""!!#"$!!$!$"##$#!!"###!!##$$$!$$"###"""#!##$$""$##!#$"#$$#!###$"$"#$"!!!##!$$""#"$""!$$$$#!"!#$$!$#$$""#!##"!"#!"###$"$"#!!!$$!$$!!$$#!!###!#"#$!"#""$"$$#$"$"$#"!#!###"$#$""!!"!#"#$#!#$!!"#!"##$$"!"!!!#!"$$$"#$"!!#""!$"!###""!!$#!#$"#$$$"#$$#!$!"!#!!"!$""#"$!!$$"!!!!#$!#"$#!$$#!"""!"$"$#!#""!$#"!#"#$$###""!$""#!$!!#!#"$""##!"!!##"!##$!##!!!#!!!"$"#!""!!"#""#"!$
@r1006
AGGCCCGTCTTGCGCTTGANGCCGCCCGAAAGAAGGCTGGGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGNGCGATACCGAAGCGTCACGGCTGAAATA
+
?B*4.D=<;+5?%B419<E$*3/.9)52#0G3,2%F<A@@G//>A5=3>-3$G!)C7007:.?!**4!D2&'!4>"E(HG;=$2-3?,901'2G<G&0A>)H;>+!
@r1007
AATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCTACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGC
+
A+(9@530A685=EF1B0*G;;&",2!1C0<''G7F5D,5.'D$)0E!"17"-2$=G4,@,BB/2>!4>7@BAA&C841,.H1F.?87*@/&!5>?"&(0>-1$45(=G<+<5(0++?=&
@r1008
TTCACGCCACGCGGGNTGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTNAGGTGCGGTGATACGTGGTGTTTTT
+
@20"G.0@+/FF5AH<$A!9&@B<-D/:?)>&G9'>8?"3?.*(E336B'H(6#<1=B-7:6$&8:$6.H1>/B#10%&,'/%9-%//!1H.<.$3<C!D.=BE8+,.>$"F9*9$&9-+%3(=549<(="1/;;(:3F?1&1(.1D?6,3,=-/7';B58=:&(:B#6:3D1"!:FC-'F0(B&A96.!%8,15GA(=$&FF<#>#5,D0/G*0#.G*;=)F/?@HC6:'BF'>9?(&;280E7-1;!'D<
@r1009
CGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACNGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTNTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGNCCCCAAATC
+
+G@!?E+"-:/*<B4=4'AA'C=G!-,@!!&A(-/82!CEHC9#3>9G(')%>!=C=.&'H%<%/D>9(5/5B:=%><6DG44:&AHDH,?(("#45+';%2'AG+%92#.-C/@0E.4F,<*<++%H:12H'058E;C?&A4.6<1'/;;991/HF;22#A:/7(!+8"C4:)BH,>!G'?B5*>97C0=;.&8B0:A3B$ECA81G/!+?BG.<H(&A9BA=.D"D1#>A!$4:E%-689G?)%B2$<"C1*>>.0:=E%*2>?=%!=.45D=G=1=%132-(,&F33;6D!#?HAE)A)@+:=H08'58$*()401
@r1010
GGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATAGATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGAC
+
(F;*'1=B;28*18503G&#+>:8&*?<BC/-8&-2E#A")A'A2<(=;7D$2!FB,3-**H<#6#@(CC=6=*>3+<,2:=$*"H'5%#;E#DC+%5DDHC9)=GF&4@FC07*9=$+:4D->37=A.*EB<A%./%*(*G/D<$C02H?B)
@r1011
NGCCCTGTCANGCTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGNCTGCAAAGATGAGGAGGGATTGCAGCGCGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATG
+
&'"#$!$*)''$*'+)%)$#("+)#*'"%(*#$!'$+$$!+)%$"+')))&"'#%!'"'(*'+&#&)%')&)!$!+(+%(##%)!!**"+$'!#%+'&%!**)$%%!&#+%%+'+$(!"'"#!!'&(%#$&*$&$)*"($&$**(('*#&*&!%(!%'!')'')'''+)&*'##'&!!((&'"%"(+!%")$!&##)#'($")!++(())&")'**&***$)'*""%#"#$!)'&"(#!'("#
@r1012
CGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTC
+
45;0CH&53H0','*61E/F')*AG(!7#?-)+1B.GC===H4)F!CG?H*E9)",FG/)3'6B9(/1$E>#(729;>,51"D:$$.@->4-02;#3>75/-0?,,.?0<1A-7;;)8EB4E&/5)24.E?C$=8/9@>-2A'(G5<7*?'?
@r1013
GCAGCTGATGCACTGGCATCGCCGTCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTA
+
>#*48+$.1(0>786D#>2%8+4A(5G-E#2#"8F">)>6B%/!+#59246</4%';&:HB8/"/4B*79>0
@r1014
TGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCNGGCA
+
<(C0GA;)F.*F$EB74A!@H<C7).3;*)G::71)%3H-
@r1015
TTNATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCNGAAACTATTAATCTGGTGAAGTTTNTCCTCTATCATTACNTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATNAATGATGTATTTTTTGATGTTNGACATCTGTTCATATCCTCACAGATAANAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTNACGAGCGNCATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAG
+
&%+()(""#+!$*+&#%('(!)%()%($""+$#&&+*)&"(%$&'%#(*!%"%(&(#$$%#&#+$#$!*%*!!)&"&&&$*$#"$+&(")"(%&)+%%%"#+"#")"*!#$!+!+&'&"%'%$$"!%+$((&&&$%$+)%!+$)*#$!&&+$#(#"%')#+*%!!#)$('$)")&&#$!*!!#'!#!'*#+)!$*!"%!!'#+*(%&!(!("%)()')**&(#%"+''*'!&%)!$%#+*&#!'%+#$)&)!++)+*%#!*($&)(%%*+!+')))'$%+!(%(&#$'$#&**$&!$))!(%"&#'#""#*('#%+$*((*%($'(*%%$%!")"(##$$%'+#*'(*+'&(%!*$++$*'#%"'(%*!&#++%)&!%+
@r1016
TNANNNCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGGACTGGCAGACGACATGGAAAAAGGNCTACCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAATAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTNTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTNAGAGGTATAAAACGATTGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCAGCATGGATTCTGTCGACCCACAGGAACNGATCACCACTCTTCGCCAGACGGCATNTAAAGGTGATGCCAGCGATGCGCAGTTCCTCGCATTACTGATCGTTGCCAACCAGTNCGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGNCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAAAGAAAACCAGCAGTTTGATGNCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTCANCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAGTCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCANAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAANATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACNCTGCTNATCGCCCTGNATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTNGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCNGCGTACCGGNATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCNGCTCCGGAAAGAAGTGGCCTGACATGACAATGTCCTACTTCCACACCNTTCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCACGACGAAAGTATGCGTACCGCCTGCTCNCCCGATGNTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGNTTTCATGAAGTTC
+
$!%!(!)&+!'#!(#*&!!$'+"&+&*%+"$%*"%')!*!(+%))*+&%$$%&*%(%"(%&($+++!(!)*#+%*#'$(&"!)+"+$"&%)%++#(('&"!+%$$"*'*&!$'*(&$*&&%$$&**(+!""#'"#'*%("+'(!+((#*&(&(#+($*$%!'&%#"++$+(+#)"*#*#"+(!'#"&#%&)%*$$%'$+%")'*(*"#%!+*!")%()$()"(*("'"!*'+("*%)%('$(%%%"&""$&(&&&*%(#+*'$%$))"#*'*(!#"**()%&%"+!(()"''"&#%)$!"!#")+*#'#!($"*"#(!)$(#%&(%*'$++%&''+%!+!!!%&$)*+#)*"!!*#+%*+$#'!&%*(*(!*#$##)#(&+&*+#+)&))*($*((&($(%'+()#*)(!$%')#&+*!*"+%()&#&)%*+""'$+$$)('($$&!#&#'"%&'"'%")$*+&&++*$+&)')"#)%"%)$**##*%%)("++''')(#!!$$#%"%+)%""$%+%+!(%#)("%''"*'%%!"("'#*+#%"!#(')'#"+(()()"%(""+'"#''*''(&'('$!')''&!"%$%%*$#)*"+(*'+$!#")((*"+')($('&"*#!+!*((&(*"*'(*#!#('"'&&$&&&)&''")!"$$$#$&"+$$*"&"+!!'+!(&%&+(###)'&%)(++$('%$'+")#'"&(")!*"+"$#"&%%)(!'#+*#(''##'%)$+!&)#*+%++%*)$&%(!$%+%##'$*+)#&#()&!!%&%($)'*%$")%*+!)(#*!+$()$$+'%!%$!")!%+"($((%(+'++!'**$'#(!!%(%%%#+%+(#!#((+&%&#"&(+&()+"%%&)'!%*$""#!)!#)&)"($+#"'%(+$#(*$*'+*#+#"%***!%($+''*#)$)$+'$!+%!&&&+"#(+"&)'*$*$!%("$!'))(%&"!&)'$(%))'%*)$)(#"!!(#(++'+%%!**+"(*!'#*%+$""%&"%'+('$*!")*""&$'$%'($*)+'+$'&!$"&$("'+!)%(*#&'%&($&&))&)+)*(%)$#"'!!*+(**$&!%*(%')##&*&+$##$'%'%'$+($%+%%*%$''')'%"$%!(!+)&$()&+&)%&!%")($'%($'"#+$+*"$%)"+*""!$)"*%$"$$+((((%)$+!*)*("*+***#$"*"#!$(#(#)#()%#%#+!&""*%*'%!("+#$(&'($$)*"(%(*"*$#)'(%(++($+#'&**+)$'&")&("$)+*#+"($!!&#+!+!#!#%#!#!%$*)!!!&#!*&&)#((*+($+#"$)'&%&(!$*%*")+)*!)&#!#&#*%%!++*+&$"(*+)#)!*&#!%+(*!$$&'!!$($"""*#$!)#%$(()!!))$&!+%&#)"'*!#$)))$*%*!'+%*$)&#*!%!#*)%)%*'*(&&""*"'$+$*'$$)(&%$!"$#*'$!)&&'
@r1017
TCTTCATCCGGCAGTCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTNTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAG
+
'256(F7,<(+!4"49"=6+2/DH1GA(&'?#<@(554G5BD.D;,&=E9'71)'H(;8:">5()#295C;>;A:7*0.-%'+>-D7>)-@>HA)C)79<4$$2<0+8>/8G1=+(#D=HB9;->%.;+H#/-%+::D#;'@;HE.6?&.>1<G!7*@A>0.6D<"&G/?$28..7+F7C,;268%"H"3#*4E+1;B@#%+DH!?E%.FH@*F11GF"9*5%'D&+A(H<,$GA?;*B'$C#5)59>C<5=@,FH):C!(?5@(3')8%-:H,A/75:?240>@>+#&==?72&<))/&6!F8GC8,,34
@r1018
ATTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATNGAATATTAAGCTCGACAGGTCNGTTATTTACCTACGACAGGANACACCCTCTTGAGCCTANAACCTTAGTAGTTTGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCNGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGTGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACTCCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTNTNGTGAGCAATGGGTATATGNATATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGANTGCCCGGG
+
$,=88E>H/CD<$B4F0+#0'H=:=>CH;';5=E!/427?D%D<2C,"A&21-9<H>F0'6,(B*G;.$0C72?G1&&5@:8G(<*H6(0(8GG6@5;BD;<-E)->'+6D,6,88(8B?,-H/?;!<G<1<@&9!5:#E!!,FGFD-%4<7%90348B1>A10''7>4F;,*99#??)!&G33E1<-CHG3ACB62F@:-7*:%?*#%9,;H.:(*@0<5F/F#7+.)!(9%,5'C$3B8H"-E7/!D##+'H?$38">B$H<*/F1>;8"=>&&#13692D',1%@B,(.4(;39",A,>!4+=2<,#4.!#20$*56*A:1').4""@2/B#-0>*;,14!?,*0DGE17!:#?>#5</'GB651/#=9!>"E'@:'$GG:A3%,G):8@E2<#.'7"?<2(-C7+2/?+9CC@2,*<2*#(;0G92"C(<C;0)=4E&,)F%7,'!32D39/*9B2.52=,762)HFF:?$E7#63'!@"H9)>6(>H-/G0/*/9A=(H25"
@r1019
GAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCTCGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGANGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGAGTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCNCA
+
=:HH&60D4#9B(/21+F)!@A+'1:%1?G6G@0"A8D5*-:H?.%8BD*'?15,).&71(76;7&-1$-"1/.5FD0B27$AD>5FBG*+?)8*G5:A3D$G3H<6*:#&(7#=01$3<F=49"*>G@:4>@-?AG)8=#5)D277,?6G*H%C%6&46>0!@+*!8A%+1>+H)E'A7-:?2A7-/&!5=/+2;FF6$8.)H6*B&:#26443'F!'2,F67/<'7)28>@B7BF>>E$+0)/60>GH&H??2E#"!5773$H14@#D"))>-#-;265"4A<'77H"6E8H$.41*,DC3A158B!G56@8#-G<,,(F+&"!HB:+*1*73<'CH<))/DD1;8@8:*7*4F483&/==(<GG3$!8/BFD=4;F958G,4+B"H&H%&"-<9%6$3+&DE;!103H!41??;+)127<0/
@r1020
NAGCGGCACGNNGCNCCATCATCCGGCATCACCACANTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCA
+
'&(**(""''!)%&*+!'(')"*+)+*"###$(*!$"(#$#+()'*#&(*')#%!#!)&')(#*$''"%)$"$#*$$%&&+&*$)("$&#**(!%&)(+!%!$'(*)#)!(!!+'
@r1021
GTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGTGGAAGANGCAAAGGCGTNGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCNCTGGTGGTGCAATGCCACAAAGAAGAGTNAATCGCNGACAACATTTTGAATGCGGTCACACGTTAGCNGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATNGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTNCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATANCTGTTTCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGNCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACC
+
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
@r1022
CAGGCGGCGGGTCTGGTCATCAAANCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATC
+
E$2+)#94?!/2#7"?;(*,HC:AA>4"6,G:FGG:"*>A:>#,9B++*<!:(B>"+4D"+A$"0G#7C5/D
@r1023
AACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATANATCTGCTCTTTCGCGGGATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGNAGACGGATGCCCCTTTTGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCTGGCGGGTATAGGTTTTATTGATGGC
+
E$%*3+!'<!:D##%7?!(!GD=H0?F-!C<*$!?3$,7341C+*#4:8(H$?4&E44412*#:4=/4D959B"'A+)5=A@A-/,(!A:EFA.)F;?A@E42*H-HH0!B>-8&41*'36.%29+856&;6<6+D9-)9-&8("?5#@"5F)8*C9F'7+.2;,)#A0B&9%>86.=C$&<G8.&H7D>&7F@6B(-BG:"!(-&D9&0,A*(,3'0#&!D/;:/.943'//%-=41&?D&?G+@"@#=C/%GE@(-*0#;,@.>4.?38(2@.&D*D2+/>:"!421,=>&"?D/2
@r1024
CGCGNGNNGNNCCTCANNTACTCNGNANCCTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACNATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCANTAGGAAGAAAATGATNTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGNAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAGGGTTGTAGGCTCAAGANGGTGTGTCCTGTCGTAGGTAAATAACTGTCCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCAGTTCGCTATAAGTTCT
+
)$"""*!"*"##&*&)$$*$**&!""(!&'&+'")+#$+**'&$)%$)#'((#!&"($'#)!)$"%!"#''$+$&(#"')+)+%"%(&)(*)!$*%'+(!$+%*'%+$##$*($'"%***!'!"&%)")$"%!!+"**$$)"#&$&(""+(!*%(+$&!*"#("%$#%%+&"'%&'!)*((+!)#"!&!)(%$%"#!+#(#%'""!(!%'%!!"!%*")%!*&%'%)("'$'+"#"$)$$$!%%&"*+!#+'&!"*$%("%!*&#!%'&!)#%&&&"#('(%!''%'%&")$$"%'('%$#*+(')%$&&%+!%)%"*+*')'+'(&"#'"*(&"!$('$+%$")")(%#"#!*"))#%#&(*"$*$!))%'!'#+'''(*+##$$*)&&!(+$'*+++*&&"!'"#'(("!!+!*)'"!)#&)!++'$*%!'&*!!')'"+$'%$)#$()%'%%+&$((+%!**
@r1025
CGTGCCGGAGTTCATCGNAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGNATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAGTACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGA
+
6+FB=(("#$HA*-@;2A"G7/HH&00@)2;#@04>(:H&8=))C0:.C,C>?>%E6E5*3*80%H=?9AC*7#4647@H>@5$,5!C&-+72#6B;67'/&EE;E15><5*H+4G+7$82G4537C47.@97CHC6<04(@7:=3#?E.!@#05:8'&D&3,=4!.1<<7)*B'"021:5-#07;,=FC5%20="&9<152?H5(),AH@6F$=&0F&'A",+(!44F:5E-E4213#E0<AE50#+.@0"+(7))'3(?/7C33"F)31"3C"H1D'8(+;#-5!G'@:9#8:>('6-(5C%D";@5F;92(*'>7>";.?1+"4'HE+.095':91D;?"$8ED$/>.3CHA(.:&:1&886*(>;8745H'46*D3'CEB1$6)9+.E2(
@r1026
GGCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATGACCACATTACTGCGGTTATAGGTCCACGTCTTATCCNACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCC
+
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
@r1027
GTTATTGAAAGAGGCAGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATNTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGNT
+
?/.-(G#2//C76F9?:4/CH=.9'""%-1'A,#9FEG#B-,>E)")<&96%54FE=7.4$D5A<?'2&E8;?E7B7@3)8E4>@!5/552&4'#H6!D5D@G32$-HA??$)A=B@HF:#;>('@*)G<DD34("7'EF=HH-/:;1C0;E18G!*C<.5<8
@r1028
CANAATNANTGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCNAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGTCGGCGCTGCGCATNAGTATTTCCCGCTGGCAGCTGGGTCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCANATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGTCCTGATGACAGGTAAACGGGTGGCAACAGTATAGAAAGACGGACGAAGGGTNGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGAATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCAGGANATCGCTGCGCGAAT
+
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
@r1029
CNGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCNGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTNCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCNCCTTTTGGGGATCACCCG
+
$#F?*,G<H+#E/*"F5#:(:"*B=?)E&"+;?<99B1G?CH*FF1>97,?%0@"//F)G?+2,0'0?E(/585)#C(7-<)+!37)&@"?>0+71C=><?,4$)3#C5$GB812+&)$"="=60;9$5)=.6;'=A54D*18?75;CG%9%=(:'H<-(#5)<,>/*:'8!<&/45-"@(6*5*E'C:FB,!3G%8''71A8.-+:F*5B,%<2%6.@8,;>*>5GD)0&0@"#>6:2HD8BDB!@%/-GD.=)@?!1:0<GH>'E..?2=B00.;*8,BBAH%!1(!#.F,)<G4$!)+,)(=8.##//.C"'0+
@r1030
NNCACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGNTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCNTTACTTGAACGAATCACCCGTAAGTTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACNTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTANAAAAAATGGATATTCATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCANCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCNGCAAAAAATCCNTTACCCGTGCGTTNGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATNCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCCCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTG
+
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
@r1031
AAACACTATGANCAATTGAGTCATAGAACTTCCATTATTCTCCTGANGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATNACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGNTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGGAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACC
+
4/?;$8)68@"-$@FD12;-$>0H')*H4A)%.768D65E(8#$3A@C.3H0=B6(/B@>&/=>)3A7>%@:<E:G),/:7&B2G=E#=D;**2<:1F?078!FC85F-F0<#3A=$@;9D-%7$F<35*5&7:H$E<17$/3?F.3AD/812&<-%":3::2#8.,'$H$+2D)#A":2=3/A727!)93$HF6F%.;D5G)8#A+!?.%@CGD'4@5?!*#51$6F#4='.31:(!2'2,!@;*="/B@+2@-?(9=B)5#3/@&7<(@HD@5C?6>=85,+&H;0H';&4(?D86004$>25@8=#9E,
@r1032
ACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCANTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGA
+
??H$7'F*H.8,(5*3,30CCC7A)=:EF0A2B.&#&CD9F+%9#19##>8#:.&;'3&H.79E(5#E*%&HH-A55$:C&&5;@?0&1#:5B+B>70/7?!?;A@!=*2->
@r1033
GTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGNACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCACTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCANTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCNGTTCACCNCCTGTTCAAACTCTGCGCTGAACTCAACACGCANCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCNCCAC
+
4=--=@?)C05HGBH:*1H&(&=6A8G+1B0B<)')4%**8>,,6=-B$FH/DB)="5%97>A)H.H5D0!5D751,;@8G!?;.?;7<9F?8/*-!08;;*2*6H?@.2,><"!82"(@?/;!>DH#*(ECCC1@FE&4;C22%,71%):@%?+>H@((.?39B"5:E/*G)"59C8(6@D#>(=2/#CAF+#<"D58'"$",20&G1&3:BH*%69""'"C=?"3#(051@2#:72<)>H"&77#C2D9"4:<#E8,)0#.;445305G,,9H3)@(.7>4E?12!FD;99H4D)54CD0/93'-@.?2<B9'#;F?8(D0,F'6"*<)7$7+'0"A-+90H$"A4=E32,@7A0'E46'<-E6"?-C$!!E"E!(4:?>1%.A"21('@@+@:0F-,(?<0("++FB+64G@#7'*"A9,
@r1034
CAGATACTCTCTTCCATCCTTAACCGGAGGTGGGNATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTNCGTTCCACTCCTGAAGTGACAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTNGCACGGTATCAGTCATTTCTCGC
+
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
@r1035
CATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATNCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCGCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGANTTCACCATGATTCAGTCAGCACCGCCGATGCTGCTGGCTGACCNTGATGAGTTCGTGTCCGNACAACTGGCGTAATCATGGCCCTTCAGNGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCNGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGACGAACNNGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAG
+
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
@r1036
GCGGCAGCNCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCNGGCAGAGTCNCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCTCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTTAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGNTGT
+
$)#*)&%*+!'(!*%#(+$(!*)'!#$(*$$(*+))&""%'"''*'!#$+##(**!$$"'!+*#!'""&&("(())$"'(!(&*#("!#''*%+&"*'!#%$')!$)'#)+++#'$"'&"*&("%"$+''#%!%*)!$'!$%(!'&(+)!(%(%#+)"!!&!%*&)#+$')"'#)**"'#(!%%(&$%*+&%"!+*'''(%&"$""'$%&%&&(&#''*')('('&&&"&')'$!%#))*$!)%&#+*&!"%+#($%*"&+*&&(&'"$&!'"$'#"!+")"*)#%##%!*"+'#'!&"*#&%+#$')"#!#$#()&(+)%#)"*+$(+#'&"$+#'(+")#)%*'##'(#!(*&*&%%'#$&&#
@r1037
AGCATTGCTTATCAATTTGTTGCAACGAACAGGTNACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCG
+
3FD:C-@/CH3,807?=8?"!*=65'8+/152!&'40.+?EF>A#A7.0!/&:A?A62-!9:.8GEDC%2H:#.9F)C%<@EH$9445$F(+7(<A8"A.,"D(12;)2=99AE2+C&G-%6?74
@r1038
GGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATNGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAAT
+
24+2%$F?6>7B&(#(7B!DBG&H3H7GC-2/>!*@.D%5,,=A*'!%H79&<#@0+5(!GH9"F>78!&G"D.?G,;$0H>9-8=#(&*B4("E0=6(+C:$G<)F,?>-#"0':)--8D"G43&5&%%(.>GG421,;//8@
@r1039
GGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGNGACACACGGAAATAGCNTCCGGCTCACCGNAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCAT
+
,18H$B'%./A%%:6:,"3#!3/$;%=:?!=E5)9:44DF#*!E+$G;8CG#80><33,@&5=>"G)-;$8C(E3;G7A*!6(7+*+&)7'@F)F35AC;0C$5-1(8=7&G:%A4A;A&+>1B?G=F"0-E>0':%.F6/4&E)&#.HE8=''%:D"#5F?8,G53*0)F(,6<"D6.64*H&-:!87+?98G/;<@6D9;<BG9(8"$#(3-G,ED;("7G/5$/-G15C1'5';&F;@$)-0G!&>520">7H.&)HE:;4<C$8=.=C6>(74$67G)B&C='%"44!#5:(-E<=;
@r1040
GATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTT
+
@"&/BB%:<!2+/%<;2(-8&8(8:=(E%6AH-"2.8'6&0-#,106)B.=1%;%:*#3$2%$(!<'8/F20>-/E@
@r1041
GGAGGAGTCCGGTATGGCTGAACCGGTAGACGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGA
+
$>6H<>?1"1)#)6F-H".$#*;7)+G$&1;?,7'=D,2'$:.1D;%82?)"D)><(3.H8.G)7)1FF(6'
@r1042
AGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGNGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCNCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGNTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGANGCGAA
+
+!/=4.%=85$=-5F3?/%-D7;2,;<E.5>E"#C9>#3"D/#<>--FA42G;B@)6%62<965.+@!<H92,(F+@>$&8/.:AA)*DA3G+27/-9+-'9'")FBC,'?/;.38+24B%=;&=&+.$*#3E4/H-4,>'&5:!:<$"1F,%/B&5")$+5H#(97@'!=1(B93'4EA;;%E'5@9=H*"&%A,93!++A<+5@G4D63F'$AAH,(.G/)/<$7.E-E10&<0AD2@+3*/#B
@r1043
GGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTC
+
B!76$+8*9(;C0G'$D==(#<1@%<>!8:<>D%=?C@?3=,EB?:?%-E$<!AEE8<>0,?E,8!070$H.%<B/07G*F"H*9="!'7%$F)>/(&;9F4-?C"#4=@
@r1044
TCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCNGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCNCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGNAGACNTTTGANGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACNCGTTCCGTGCTGTCCA
+
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
@r1045
NAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGANAGAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTANGCAGAGACAGGCGAATCCCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGNTCGATACGAAAAAATCCTGGCCAGCAGAGGCNTCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCATGGCGNCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGANNTCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGGATC
+
$+&"*")%#&*)$#!$%)'$!"!#+)$'$+&!!!#()('$##*!%+%''&((*#)(*''&%)&'')!%'")%!+''+'%+"%$(&(#"&%+(!'#+$$*('(#)&*)&($'(**!&&!!)#+&"+)&++'($"&&"+&'(*"&)$"&*&*&$+#"*#*+)"!$(($$)*)%#"!%*'&%$%*+)#*$%(*#+'*&$$)%&(%+$$'"+%!$+"(&#%)%$"&#*+"+##""$+'+($&%$($*()($")#($$!(''+&$()")$%')''(')!*!%"+*%%##''!%(""#!"+%*"&(!!&$&&**#"'))"*"("%%)&#+&*#(*+"%!)%)*'"#''&)&(!%(**)((!#%!%*!'+*'+())(#%#(&(!*$$!*'$$!"!%(')($$(&"'(%%$*!&!#*#+')$$'#%*#!&+#*#*((!&*&%%($"#("%(&(*#(!%$$'()!!)()$$""*&*!$%$++))$$!!)"%"*$"$%+*%$'*%$#)"$('%(*!+)*+'%##%)*!#$+!++(($*&'+*%'#("#'++*!"&$'**!**($!)(!%$#&)"$')#
@r1046
TCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCAT
+
B99&'7D*;G@4/2E'''8%8((9A>0E8'%'%4?/""@23-%=-A$DCD#D409"+1AB<@B7+3!=.3-8D60.08%2@&<!9'F!"3'(.;=,)C&D+H#C<=/.$:4C665#38A$**',8@=A")=-%9/00H)067$76!<>;.+F.*DA.1!/"E,H:F:>):
@r1047
GTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATNCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCNTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCNGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGNTGATTCGTGGAACAGATACTCTCTTNCATCCGTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACTTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGTTGTTCTTTCAGTTCTTCAANTCGGATATTGGTTACGTCTGCATGTGCTANCTGCGCCCNTATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGCTAACTCTGTTGAANGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCNTANCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAN
+
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
@r1048
ATAGTATCGTGATGACAGAGGCAGGGAGTGGGACAANATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCANTGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAANATANTAAATTANATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTNGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAG
+
&!E*..40@?51$B3"!%(C:+E;>97)<7(DC$+8DF3/6+"?F?#$,&98/$17;;*"B*2?("C&9B)#*3(%5<,>+B,!+CF,55>A@7-/51@(H8!F8758:9G/6%#%(%E9(?2;1&01:!5C1&55H:))!B!:"*.F2DH/6H()G;+#*4;'8>1@"%2@*9GE-E++B&0'(;C3+E'$;@%!>DE/$0A?5C34(70#H"'&'D1@6!*602F:5%4!D/6>1AH9:6?C(?#5.=5BA#&F0!!::C5%!+1=.E>)<G3A;*.!;4B2E#!G9%25,/C4B&:?!?8/8'9:60$'%AC')+C7-<2F+.:&"=:A9&)9(>A0D.=7:
@r1049
NNCGCANANACNTNANNNNNTGGAGTACAAAAGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGNGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGNTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCNGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACNNAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGNCAATGGTGGGGATTGTCGGGAGTATCGGCAGNGCCATAGGCGGGGTTGTTGGTGGCGNCGCNTCGCGTCAGGCGGTACAGCCANTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGNAGGATTTACGGGAACCGGCGGCAAATATGGGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGTATTGGCGTGGGGAATCTTNACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACANCGGGCAGCATGGCAGACANCCGGTCGCAGGCNTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGNGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTNTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGNGTGACGCTTTCTGTCCCCCNTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGANGCCGCCTTATGAGTGGCNGCAGATAAANGTGACCTNCGCAAAATGGTCGTCGCGGGTCANTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTNAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCNGCCAGCGTGGTGCTCTGGGAAA
+
%%$*&("&!&!'*"&"&'!!+!)$(*+!%*+&#&"%*'!*&+'&##'""'+)+'"$("$!!(+*!%'!+#'*&+(((*'"&)!%$#*"+("!&"*))%*(*$&$"&)!#!%+!*##%%!&&!%$)('$+)"#$)$+!%%&*!))%%%##'%+))(")!(+&$!)'*!$%$+()*(+#&'%&&%+)'&$"%#$*"+%%%#!$+('+$+(("#&%+"*&('$#!!"%&+!+"#!#)($%!&')&$$!)%#!)###'!"++'$'!'$"$$('$%(*(()!&)!##%"!"+"$$$')(+'($&$!&)#""&(%&$!'+%++!'&%%"!&+)!$)+#'!"&'+*&#&*+'$$&)!'#"')+'*'*&+#*""%%%+*!+%+*"$'%&!'%&()'!"($")&!!$!)&+"$"+$'##"&!$$*%%%""%$'!(')+&$%&*"&(#%(*)$!')%+"&+)*!*'(##)$"%!+#$%%'*+#!(#+#"!'$!!#!*'(+#+)((*'&((&)&'**!('+((+)*$+"&'#*##%(!##!$$*+#$&#"("'$&*(*%!!)!*%*$"*+$(+*($&*(&#'%#%$#)&!%"(++&*'*')#!)''&!#+%#**")"+#'"!*))"#%!($)$(&#&%#%!&#!+'*#%$(*!*%'&%!+(+*$)!&+(+'*(+'*#+)!!$*&'&"(*")))!*($!"%!"*'++#!'+'$"&!*($''#)($#$%+("!(#$"))&*'!$#!+&"(")&++$#*&'*!"%%%%)!&)+*#$'#(**""")#*&()%!$%**&#*&&)!#%*+%*+"&+&)&)(!#)!"%!()!+!*)(+(*$'#)'"%!*#%()%$##"%#)#!"%#%$"#!('+$$$$(%'$%)!"'#'%&!!'$!*()*'"'$+$&#)("'+)+%*"&)%&+"&(($$$"(')%%'&$$("+#$(++$(+#+$*+&"*%+%)!+*%%")*(()%)''+&#)%'+&*')&"*()$%$""$!"+%%%%(*#%"$)!+()"#()+&'&)$%%!"("#)**&$$'+!)*#&+%)+&*+'&'"%(%#*"##%++*&%)""&(+(+)'*$"'#""'+$$'")#*$#&%*"+(!"(&$'*&#(+*!"*+$%!)#+!(#))#+*!"'&!)')))'%#%$&$)"#)$!!"#$%!%!#&!(!(&!%("((&$#*('!")"+&*#%$!&)&"+$)()#'!%)#*"$")!$%%$#$#+(#(!%('&&(+%&*$))$')!*"''#+*%"!&&&$+!#*"*&'+%&+$((&&*(!*%)%#!(($#$*%$*$(&"'+$(##+'*!*"&$)+'*%%")*%*$!*'+$)#)!$*%*&%))(%*)$*+$)!%))%+*%!!))**""&#+$&(')&++'**!*&"")#(&$*
@r1050
ANGGCATCACAGTATCCTGATGACAGAGGCAGGGAGTGGGACAAAATGGAAATCAAATAATGATTTNATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATNAAAAAGCTGAACCAGAAA
+
$$'+!+&*()!')%"!#("%#+((%#'!"&+'#'"!!%$%'"%&'*$*("%!(#'%"%!!($++()%'!"%&!*'''(($""#"'#*+*"'!+%%$%(&*)$)+"!%**''''**'$#*(+#%%+!))'!&+(&&+#")(('#)($$*'#+&$+)$"*%
@r1051
ANCGGTACGCTGAGGGCGGAAAAAATCGTCGGGGNCATTGTAAAGGCGGCGAGCGCNGCTTTTCCNCGCCAGCGTNAAAGNAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAG
+
&":24B4")1,.FCD-62C%B-G0)>&/,F)+,D$.G#H2%G#/;+&7?C8-:%!83*F?%)<D*%@'+B:*&#/BH@/?.C*#&C,E92$*-F4!C,81C;"A&D@>(-3*C%=G/<,88E><..-+D:0?';>B<A0-60A%.,,/4BG*F95:<'=)G;-'#><5F7+G?3+"$D,A*9
@r1052
TGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGNTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGCGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCNCGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGNGCACTGGCTAACCAGGCTGGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGGAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACNTCTCTGCCCGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCCTCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTNCCCAATTTTATTCAATAAGTCAATATCATGCCGTTAA
+
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
@r1053
CACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGNGTCGGATCGCCAACAACCTGCCGGAACAGTACGACGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAANCGTGACCAGNACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGNAAANGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTNAGCGAGCTGGTTGATATGGTTTANGAGT
+
+*"%!$&$"+!%+"%*$)%$!'#!!&#%'*+)%&)+'(*++&%&&!**)#*!&'!'"$(&$(#(+&%+(%$&"%'&(&$%&#'"#("!#*+*&(*$##!(%$#'#*(!$)"'""&#((#+##*$$)*(%'!"***("&+$&#%(&&(+&)("'%"*%'&+#*)&'+*&#")*"!#!%%##()'"%('%#+(""+!*'%"*""+*%*!)))$)%("!&"')&"*!%)"!%'$$(&*)**(!#))%&"$+#"!'$+'+"&!())*%(*(''*%"!*(+(*+')$"%"')#%#'&"&)"(#%(#$&)"+&)'*(#'('&(((!(!$%%('#$&'&+$#%")&&$$!)(&%#"''+(+#)!$#+)**'"#(#!%$!$)))$)++!)%$+')##(*()+!#"$+*)$()+'%*""##!+)&''!$*"!'!)(%'#
@r1054
AATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATNCTTAAACCACTTGTGTGGGCATGAGCACNCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCNTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACNTAATTCCATCCTGT
+
)6;D-1GAA/8!0@6?C7=:3568"D4G>:62&20*3(+#&B'>@@DH,#3D),79-@0;5#)0B+-3B@F*%;C4::*=GA7.,)8A>6-G?!17(0H?4$%D:--#E"B!F<9&@D##<51;(0D##$9&@.%BFE!0'+)#@B8#8C'!+AGD>?CD*!"39;'75A3=(H:"/+4<%;937;!)$4&->"(;#*:5)0BE8-H0<5:0,:(1DG-9/'$,H?,A90%!+!=)@5GE,;H&E&=9B2;19
@r1055
CNTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAANGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTACTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGCAGCCTTGAAACAGTTC
+
!%,?.&/=#6@?,>C3=1<1B*,$F*&B8%'G*,;'?B:!=0':.:#CFC2C&&&55$;!#;G2?')'E4:#F>4A*>,%1:+;-@>!&(%)(74D45?8358;/5D@6.!C$?C4C7>%293=.*3618*&E.,69BH;C($2=@4H'#1;6/''6-',;FG#6+348#(&-FF.6$0'32:53#(@@8-HG3+<6B4*%H>#79*8=1*76G4-+".5H1;*A/"E-7&CA'--F(5C8>$>6?"H6B(6/%B;2)(-F>-!*2
@r1056
ATCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGNAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGANCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCA
+
/:+&2<&G@#>9G!=DB6419:)-H:$26,?H$?AH<"7.@91!*DC"$1>(&@.+:-5&H#*7%%4D='%5:.A::=E."D)+)<5$:;>C%2@D()"0!*;"#0D#1;CC/*D<*>F6+5-&BE'7(A?=?=5B/9&'!FHAA:>#"HH'"4G949,1<'$B?+A(GC,@B0";*2'&@AFB>*C:5344G/E"8/@//;&+0D,2DF0-76C$?'FAH2A90>.F:C-*@>D3)D2F&+??!&+?E3081$,;:&/./1>@0!15/>*&H4C4/)?;3:F4E'08E4B*26=.(0%/@$#'/,5%8A=3=*+;@75/"F2C"A/?/%;>#')A!3;6*3<36./!:13+<8C@G7?8.@2$
@r1057
GTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCCATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATA
+
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
@r1058
ATGAAAGTCCGGCATCTCAATCCCCGCCAGANGATAAGCGTCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTACTGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTNCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCAC
+
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
@r1059
GATCTTTAGCTGTCTTGGTTTACCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAAC
+
+9>%"(A14'81BE>177:%/@>(FE;E=8F)!H@=16,,B8EE7=GD!F/@*7A6()/<'<A.5@AD$F,A#9<0+%!5&$,5$G%>$E9"1%:E553"=>*%8$2/;%>:<GC:=C4!3:.G$866A*@8::,;.;48F+1=1-8&@>DD=6D/EG&2)EHA3
@r1060
NCNNNGNNNANNNNNNNCTNANNNGNNTANNNGNNNCNACANNNTACNCCTGNNTNCAATNTGNCAGNACNNNANTNTANTNANCNNTATNNTNGTTGCCCTGGTCCNNNTNCNNATGNNNNNNNNNANNAGNNNCGNGACACNCCNGNGANCCNNNGNTGCNANNNNNNCACAGCCATNTNTTCTNNCGANANGNGTCTTCNNGTCTATTGGGANGNATNGCTNANTNTNNNNNANNNNNNGNGANCNCANGTTCTNNCNNANNNNNANNGCAGNNNCACCNNGNTGGGNCNAAATNATTNGNCATNATNCNANANTAGGNNTGNNACCNNANNNGATNNANNNNATTCNTNNTTCGNGNCATCNNTNNACNNANTCAANNNNANGATTNNNNNNNCGNAGATANANGNNGNCTNTCGTANNTTGNTCNCGCNNACNNNATTATATTCCGGNNTTTANATNCCNGANGTNNTNTNNCNNNAACGTAGNNCA
+
!"#"$"#$""""##"$"$$$$$"$$"!"$"!!#"!!!#$"$###$"$#!!#!"$"""""#$$!$"$#"$!#!!#""#$!!#!#!#""#$$"#$"##$!!$$#$!!$"!!!$!#$#!"$#!!!!!!$!$!#$$!!#$#$$$!""$#$"#!"$"$""#!"""#$"##$!#""!$$"!"$#$"#!#$!"!$$##!$"$#$#$!$#!!#$"$$###$$#"$"$"!$"$!"!!"$$"!!$"#$"!!"$!!$!!$$!!""$###"#$!"!"#"!#!#$$$"!####!#!!"!"#!"$#$$"""!"!"!!!#$$!!"#"$"!$$#!$#$"$$!!$!#$"!$$""$"!"#"$"#$$"#!$"$"!""!$!!"""#$$$#!!"!"$!#$$#!!$!#!$#"""!$#"$$!#"""!!!#!$!!!"$"!$"##$"!"##!$$#!#""!$""!"###!!#$"!#!$!""#""!#$!#!"##"#$!$#!"$!"!$!$"$$"!"!"""
@r1061
GTAAGTATTTCCTTAGATAACAATTGATTGAANGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGNGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATG
+
$30;,$)H+1E8F69@85#*;@DD6880<2=44-BA%@*H+0(E*0E'&)<@=8D#FC:00BG2=-E4!-C9>49E.:4'A2,0)5C390E#%<*4-"F(-?,,D&003!309E3(40>!D)2*A;$#/H4:<+/'=392!E.*<6-.C-4E!&'#A#)B+B2=37=AB+1+6#<!=10*)81H50$?-G38+.8-%89#-/2F70DBB3?'(E:%(H8
@r1062
TACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTG
+
C0&;$<'<H1<'75'6;2B<4)G!$946+-B(++9&/%>F#(7<B&
@r1063
CCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGC
+
-+E-5'%/4+&3(2C<);!<5G3D2?78>>'/88",(;#687>;<!72=(1:#E.:&5C$B))(79CG<64&@?6=F:$7@;57@4*&#>(=GH=9FA4#-2'?G0*."3:77#9><=-3,*@9+94/&+/28A@9:%'C9@-%442"5
@r1064
GTGGTTTTCGTCCCCNAATCCNTACCGGATGCANTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCC
+
+20>1%#<6H*9.+(2+F(,,8>'&BB5'*6/+.0A%$*:HH7!4,,/$2)!6,+C7?-6B3$<"HH73$5=*G%,>C**&$9(?*?C@3/7H;G@63E&5?)%2#/%<F:G;&<H%7#<A'#"',A%((A:C#)%+/5-)B(>F0#1=E=&7B212E'%+*"D=$+<*D.",G68B?>H-BA+11905E((083*
@r1065
TTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAAACGGTAATACACCGTTCGCCAGACCTTNNCTTCGATAANCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACNGGAAGTTGTTTTACTGGATCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATCCAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCANCCGGATACAGGCCTCGCTTCCGGCAATACTCGTNAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACNGATGCTT
+
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
@r1066
GTCTGGNTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTNGGGACGAAA
+
FD3+#"#7C<%1*8&+'-)B4-+3/+65?2E,*:.H"6D"EC>,G11"?571:1C=>)<@<4F<AHHD9"!2B>%'):.GF+=(1!9?E5:A0(@!#DFG68A5,C,=5$.6*.3"74?7(/A'4.$5(:6486E'&#)'75ED#)=;9@!7..!5*6E66@:8&5D+F7;;8@+D8@+?*/=&!')GH3@G2"F"/9<H7918:5H5+-$08E
@r1067
TCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCTTATACGTTTGCCAGCAATGAGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTNTTATAAAACAGTGAGTGGTNAACGATGCGTAATGTGTGTATNGCCGTTGCTGTCTTTGC
+
?C-70<00:F>2(1H.*@G60""E-8H#6$5@#'@26H24H*E+7?/;G68-,H5*>-3>:?-:2'"!?*C.8$;D?B!+33FG?)7A)$;6%">C)C"(C:5'1=F8>H$#*/$@+9%=*H=:3+09!?-H;A'61?!.32)D?4BG18$042+&79F%H/&H;8FGB4D707@$*?F1&+=3<<#.,'94D)&,'.!+,?6EF/C5C!544*#G383+95/4G83>1<81E:.D6%/$CA;-5.*6<F65-E1
@r1068
GACCTTATTCCTACTTAAATAGAGCAAATNCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGANCTGTTGGCCGCCAATCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTNCAATGGCATACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACNGTAATCGACGCAACGATGTGCGCCATTATCGCCTGG
+
*?6!40#-G0:A11&6!'$)%;8:@+E!G??9?$<)>06*46"DA=G5*.+%?5E&"&-4;C?2C8B<E>#CA%-&C%,"C*-;A:C&!@(:.32%/2&B7($A@9):)1%41&H!5F7*9E*E4,H?A".%B<7>E)?,55$/@H@?3/+:>&?6D62D:)81>,%8(.CB3F8G7)<*>(E/;'""!FG?&:'0D?3"3@*F+/F*+F="D-.AH
@r1069
CTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTNTTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATG
+
H+35.@>+*69.&G4#++2A&'5D;//"3/*.(HB+3HA6+0"7-E,/3D@10ACG%6B;A%$D336$$.'38<(2.2"F@!7HG0>$"1.5E@?5.E>"3#,<+:&)F5D1C@C4%@3/<.,0A'H=H>?8H@;9(C<0$1$/=:BG>*)
@r1070
NNNCATTACAGTAAGNTTTTCCACAGATGAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTNATTGTCCGGTACANCCGTGAGTGGCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACNCACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATANAAATTTATAATCTGCTGGCCGGAACTAANGAATTTATTGGTGAAGGTGACGAATATATTCCGCCTAATACCGGTCTGCCTGCAAACAGTACCGATATNGCANCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAA
+
!!$'(%'*#(%)*%%$#%##)'))'(#$"*(*++')'**+)&*(+&''!&$)'%'*$"##%#$'*$($*&#$#(!+$)#)**($'%%(%#'%(!$"')&$$'$+#&)#&$&#+($'##)(#&$!&#)*#%#%%)($$("*'%%!$%&"!%*%'%+"!'#'#(&"%!&(!#$)#+$&+**$$$#$#(+$$)'#"(&('!'(++*+%)!%#&')*&('"$'$!'%&'((#'"+*%*'&$&()+&'&!+$!$#(("+%)+($&*')*!$*!#$+*#!*)'%++#+*!#"$%%*!"#()#"+&++"%++(+$)+*$&#'&++)!##&#"$&)%*"$"+%**"%(#))***$+$%&#"+'#$&!#$&&)$$#'*#!'*&"$*$$!$&(!"*&(!%*$*$()'&(++*&""%"'##&'(#('%(''"+$)&'")#'*)(&'$$"#&$'(&+&")'(+'*$$(#&%#)$(*")((!&')"'#&#%')""&!'&'))(&$*&"!$'!*)*+%&")#)+!"*'$')"$#*(+)(+%+**$+"%"$+)!("$)!$$#*))&!&+))"*!+'"!'+!$*#+*$(%)*+$$%$!&(%**"#)!)+)(%"!+'++#&'(!$'!
@r1071
CCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAATTGTGGATAAA
+
D0#3,7(@2&0*:(A')?B7C57)':D$+EH3:$><?67)@GGD-'@659-'/G2&>;9+<@=";
@r1072
GTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCTTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGAAAANAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGNCTCCTNTAACTGCGCCGTTAACCNGGANGTGCTGACGTCCCGCCCGGCAATCCGTAC
+
"6///)(G/5G/."D%?H5,"C3:%/>'!<0<64>5""85(D-D5C0D2>E*@(G*#<1F@$=F&!<%:*C1B7:><+A!=#4**<=H$8&-@#:(5&B>5+769HB'.*7D&-H>'547"C5FH;8,#',?->:-')H>95$$.7C-F7!::+,!%?$-*+$6':1A=/*@)*E-+5.5*9!6D2-:@;/'9;E:G(;1099FC0&$>;FC2B:6:/A39CA2##>%/8;.1>%:#%C3A6%HB!'.,C"6C<2%6420>-5?2*EDC<E.7F/G-D&+H6.7&&);A:70'&*B9?8D89?G8<+D;)4G>B616E3!$4C1&G,0D,:=8*>H!$&7C(32F7B!H)#C.-"#0*>,#?F((4%:*E;/:.4="1D.""<A;)0B.(E9G$4<1(B6#*D,H@1C4'5F8%FH,E5#C7>92H*H!0F7;94'"'+;D71;-031<!E/72
@r1073
CAGGCCATGTTGTTGCTGTATGCCGGNTTAAACGTTCCGTCCCAGATACCGCTNTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGTGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGNTGATTTCAGGGTATTACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGNCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACC
+
3?C-<0<05"+,3:#F;;GD6#40@DH?!7,F;,6-!$&BB/"*?'0@;-BG2139996@47/2H69706):774?A:!9H?A<0-&C$!B-AD<#,!+-,%H#H3:&,/6-)51,3?D624'B$;F,F+&?20?F")A"HE*C%$")5C)D(+;5AE)/(4#51.H7H1G:$:E+HA,E*44H%<5?850BE3D7D*(64>H$&,'3D%%(%G:6C2*'6AGE!.44>6!:1;@5"0A63!2*3@0DBE$4(B06*(2(B,05&@48#A2:7:+/7.;135:G,&D4.*6DF6<0>.)47B'-88*(@<2D<15!&26H$?>6H3#80!&3D5?=:*G9A1B'(!*F9>%20E476%A+=.#CG<@E-*31G1?&6A('G.%=#C()@.?@8*(;!#%*+=6,-E16H$E0#*15')DE4#G*;C62H%2?591@.*?33!'2<2,-<90+99&?+$4$)F(C7G!;!B@6(
@r1074
ACATCCCTTACACTGGTGTNTTCAGCAAAGCGTTAACCGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGNGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGNTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGNGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCNCTGACGTTCNCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTAC
+
+H$(5F/6+7+/,1;@=)C$=*E,8<:)5F&H7*A,@)?:7,<#FA<1C?,.C*#D50(&'7F<=;.'E@+,H.D#D&H-@(&1..<($'*?'9;<+":G-6GE:6>%4#0<,-D%B'?'B*-68;5(.9C*#42'FH5=<%9E<(0:=E.*&G)#..EA:=3?*,3>.400/=-4BH!)B&HD951*.7E=*@((002/G!)E71BEG92.%@*$!5@:<2-"A$HD*#D*A(A@2D(//(AA+%,EF*.*E@<*B:829&88E?>@+AB4)!A6.5@(<F,=.)$%)<F;;6FA%437#7<E#.BF0;>("@,C9#039;4F)7=7F>E3('EH1B*/D02*&@<5*<;*78.(-F,1A-9.F6BH"E9E1<C=2/,=)=!A#D#/(;%>44(74,D>2/)*%B:87%#4A8-0H@2&(:;AFD('/
@r1075
NGATAGCTGTCGTCATAGGACACAGCGGTNAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGGAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTACTCACATTTCATAGGTAATGCCATAAGTCANATCGGCTGAANTCCACACGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGNCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGC
+
!;52@'>2-BFD4/544!8EB$H0,6BA2-48?<2(>==--<2'@;;E->5;:+&2H:9(87-<,%0=83)5&??1"<)H4F+#A&)(9953!:D)?*$4D<71A#5-&/12D@C"%?D.(:+=D-.:$AA!"-#BC8@2)1-4ACA$2H(554%;C*7.1&A;.899?*6$2H)-F>7&HE!6@D@FF;)!(+4><2?4'>(0H/3D2FD#'+DHC,,#+H&*FB934D!?G3C+E@3G><@#$#8+>?3:;G1A:G1F))!1B5#D(E%+,!!9C+9=D-($CCH"8;2&%+/DB-GA?H6B$C..-EB';#76C.D'"62F;.*,1<'?;,'>(,-6B!D"9&:/9!%20F&"'0;,51"%$,#6G>C8-H9*D)'?FFA2G(@'!=26"'0<=.B7*2/C+D5C4C?&!E4!09>A%GC91'G;B=5A0F0=.(#G=9/0=-.3;/B3G;'97E$;A5"3)=-F;-!@/:B!=#63@
@r1076
CGTTATATTTACTATCTAGCCANAGATAATATNCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAACTGCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTNCAAATATCCATGAACATAAA
+
$#&+#*"&!*'(*!***!$%+#'%$##!)'#$#$"'+)$!"!&%+&#("!++(%+"&$&+)('#!)$)%!"$+#*!)"'++#'$%&'%!&)!#()#$"&$%+"$"&('%'#$($*#+#+*))&$(+"#''%)#+*%$($+))!#'&+!$'!$'(+!$(*#'(*")%(+!'!$#!+"*!'%*$*%""'&#(#*"&"&++&($+#(#')&'$(+*%"(*$(%"(#'%'$((('&+$
@r1077
CAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACACAACCAATTGCATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAGATAAATTCATATAAATAACATACAGATAACCATCTGCNGTGATAAATTATCTATGGCGGTGTTGACATANATACAACTGGCAGTGATACTGAGCACATCAGCAGGACGCCGTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGCCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTACGGAT
+
D-$=&.+D<>>!67)FH0BD(8!@3(15%54<@E*<BA9+0:0:>3#EB;A/(#5F/&'/B"(5F=.:9;&(/(+B8E%GBD&E54>>C;20(92(G05GD8:1D18.:@%#9%<--DG9$"!90A6</D2)=&42(C=58F)!>6#>E/5F'H4DA65A&<-19'2"1)F!9?>6!/)@:%.7<0"/!C/5,(:$:69A+H40G&*#G;C="C1H$&,*.H,(H2H;5(>$8G'*"??1)$-))<&<1E52&*H#?<6@!&5E(/4(.A5''<'/#43&,/$+&+G4-:5"-.%$*E.4&H?B80-G1H/!GC"?D0C.133)="#;HBA7!H!H2=C.CG:C>A";*##51,/-,!D&'-%DG-;B6+4.A1*,2<156/!1;7
@r1078
CGCTNAGNCNCGGCCNGNCGTTNTATATNTNTCNGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGAC
+
)#)&$"%$!"*!')$""(&*)$!(%#$%'($&++'&!*("+('*$(%&#!)"(+)!)))%*)('"&'!"$%*&#!(&()'"&)
@r1079
TGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACA
+
#&C8@=B*5)G05B7</G>:'3<%$>!"E#32=-=C"D.B@+'#H&A>DF+--"2)<4&4HB50$(*3*1(%,9%@+/F9)C.3+ED0#
@r1080
GTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGNAAGATGAGCACGAACCAGGTTTTTANGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCNGTATATGGAGTTAAAAGATGACCATCTGCATTACTGAGCTAATAACAGGGCTGCNGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACGTCAGCAAAACGCTATTCACGCAGNACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTCGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGTTGGAGGCAGAANGCTGGAAGTGTG
+
0#>=G;"%FG=H>B7"2"@8%;0<#"D*5>4993A9=<=!,$-$66H#3%E/"892+#1&#&=?",F@#++A$B)7#C;C,#4:@H+%A05&#,@#&C9B!C859"B&/2,,095&1.8:%3=2,G"@%0!CA>3/8*#%4>!;3?6%7+7=F+G482);3G*9B-)!38=4(>C:==HF291EE$.5",&)B'B=>>)@@074;5<6)6!*)%69$=09=)<G*--?+*(-25-D(#,'%E>F$"G#63HC#<3&*0C2@:'/=:':@%CG$:C=B/#811<*#1"'@A.6B<")%&0.:'%33.=7$=)389;+">E:G6-!/8*<3$5&:;'/?<?7E%-.",(7'BD$&()B;*5+.81+B#2A?!2F(3*"C)4->D%+/;D"5B#<C4"%@//%&20'3<9!?$6.DEC+%5D3;GH3$+%#>/?
@r1081
TCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGNGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAA
+
<6C1+*!C93&>>.>;"@@(50HB/35%E'))968*+)-7>EC!1=>1%++4"!H+;8=+(&,F*)2$:=8@+::,HA$ED34+5&7.6.?G;$..C9#GA1*2E:"<<-:H%E0&;1B4A%1:F7.D=4?0
@r1082
ATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATAACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCNGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGTGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAATCNTCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGANTCAGGTTTGTGCCAATACCAGTAGAAACAGANGAAGAATTTCATACGTTAGCNGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGNTAAAAACGTCGATGACATNTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGGCTCATTTAAGCCTGGNAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGC
+
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
@r1083
AGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATNACCTCAGAACTCCA
+
%HE;0)@!2E+@:>G+>>DE.B(85<F/+4F.6'.6H=>+:>84)D,>(*H=0;%$+'22E:/C9)
@r1084
CGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCACCGCGCCCGTTTAATATCCGGATGCGC
+
(7B!;C,H=2"$=5*+*""$1#(?(%<0#+/3C(6(1F6)G//."7G*C%#$05D4.&$/7D9;"*"5C;5&()B2(8@592;4D@*B@AC'=.)*9'C&B%-G'($5!>(D<3&C%8$,5D9AC=H@,9&#=GAD&9463=>8.2'H+/-*'G%<?%<,/6(2&6#3&(;+-G6'")'&%<!?0/;%F.+;:</'E9)1BAC8)E/A3A.F9"D:
@r1085
GNATNATCCGTTCNNGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAG
+
&!%*"#*+&+''$(""*#))$#"(#*$(&!$!+!!&%"(#++!&+&)'!'%))%%()#"&&#)"(#$$$$(("'*$))+(
@r1086
CNNGNCNNNATGNACTNNNNATCCTNNNTTANNCNNNGNNNGNGCGTCTNTTNNNNACATGNNTTCGNTNCAACAGGNNTNNNGNNNCNANCATNNCCANCAGGNNCNGANNGNGAGNNTGCTNNTTTNTGNTCNNNNCTNNTCCNANANCTGGCAANNNTNATNGNCATNNNANACNTNAGANNGGTNNNCCNNGTNTNANNNGNACNANNNGCNNNGNNNTNNNANNNGNCNTANNATNGNGANTGNTNAGGNNNGNNCACGTTTCNCNNTCNNATTGANNNANNNT
+
##$!$#$!"##"$#$"##"##"#$$"!!$$##"""#"$$$"$"$!!$$!!"!!"!!$"$#"!!!$""!"#!$$#!#"#!$"#!$#"$"!!!$#$#"##""!$$!!"!"$"!!"$$"!#$!"""$$!$$!"#"#$"!""$$!$""#$""$"$"$$##"!"#"!!##"$!"$"!!#"#$!#!!!!!$$!!""#""#!#"$$!$!#"#"#$!#"""$$"##"!#"$!#$$$!#$""!$""!"$$$##!"#"!#"""!!$$"!#!"##$$""!$"!!!!!$"$"#!!#"!!!"
@r1087
TATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTNATTGGAATAGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACCACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATNTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCAGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCNGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACG
+
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
@r1088
ATTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGNGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCG
+
!C+21/'5=<#<2A#9,:C:10+B?-/6&4H*4.5=:8!3-(.B#&H/+H'G8C(E(C'A9FH!*-3(*#%D!D,6,0F;<D3G5=DA40$*F#"E#@DCCA-463CC39*D/-!H&B'*-H-:(F@#'?1+'B3=:6E%6C:+3F039'(G8FGA@<H93'-C/&2%/6G;C3425G8%0'"!,(=;C#=3)1C>12?'.:3-1B&4?%7&5<*<76@&D&/
@r1089
CACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCATTATCTGATAGNTAATGTTCTGTTAAAATATCTCCGGCC
+
66"528D48D4/4@9?=9".!FB#,<A6A4.43613A;51C272@H1D%H257BB'9E/BCD=0-!/6+94:%<2H8*1B!"47E/8&?.399&@<0)%1"%>3:-11?$,6D&';(/2DG?$!;4@HF>!;&$1F472.1=&'A$HC!+8%(B
@r1090
AGCGCCTGCCNGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGNCGCCTTATCAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTNAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGNTATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAANAAGGTGAGCCGGTCACCTGGCCGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTCTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCCAACCTGNACGGTATGGNCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATNGAGCAGTGCAGCGAACTGAGCGCNGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGTTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCNAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATNCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGNGGGAAAGATATTTCNCCTGCGTGAATA
+
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
@r1091
ANGCNNNNNGTGCTCANATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGNCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCG
+
%'*#"&#*$%*%')&!+'(*!)#$&!'*'&$"'&"'#!&!"&%*(')%(+$"*(*'$%!**+#$""!'!((!($)#()!%&&##$#&&"(!#')(!')&'!%$*'%%'&+&('+#&$(%#(!!(*+!*(%'%&'$#%++&
@r1092
TGAGTTCAGCGCAGAGTTTGAACAGGTGGTGNACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACNTTATTTTTTCTGTAATGAGCAGANCGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGAGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCNGACGGTTTCTAACCTGTACGGTAT
+
/6."/C7*.0.42E87D/<&1<G0810:F71A$=C2&)D6&D/<.&,0??<#5'F;.F"+6+)0#*1"!9=5B;FH&8.%G(-6%A-0,D+)CH2<E6?"0*=GH($/013=182C$4?24")53*3H'67GE11+=.,,/C$!7/(H>)+3;%E#D),!@F<#H9=8$?%(B04'$#D;-9&<<+#=<%<F9971>F$*,3!7178*G41,%1'GEDH7#(HB55%>D),3=&>1:'1:$=,*4#06E7<9FB'&0@=$<(A:DAG&D.,=10&<;DG2!5#%+#<2A::-G3B>
@r1093
GNAGTACGANAAANCATCGTNNCAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACNGCAGGAATACCNGCCTCTTCCAATAACACTAAACTCCAACATATAGCANCCCTTAATTTTATTAAAATCACCGCAATTTATTTGNCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATAC
+
!#$**##')#*(())'&!&$$%+)'&**+)*%"($*)$'#$(%(+%+')(!'"$%!%#'&*#!!+*)#')&+$+#&!&!#"+!$&&#*!(#$((#+)!+'#*')&*%$%"#&$"*&)+(*&&)&'*!%*#$%##+$+(%%#$''%((+)!!)$('+"!*"!'")*(%!#(#$*''+#$'(+#&##"*%(&$**$%(!((&&!&%+(#
@r1094
GATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTNAAATTTCTGCTCATTTGACGCCAGCAGTTGG
+
)4=/'2==;8:G?;?1*?)A0@<$"2+F&(@CC&-?B9(9GB:49&707#73+H945G&'3E8<@4E3CC)%)7A-5.GF"7C"E%="3E:;:D<8<<$H>
@r1095
GCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAANGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTAC
+
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
@r1096
NCCGGANCACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCANGCCAGCGNGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTNGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTC
+
""%$&**))%+%+&#$"*(+"""''$"'%+*!!(*%*%()+))%&+$"%&!&"%!)$#)'&%($$(!(%#'+("+'&"""""'!'+&*#"$+'%#)+!%"#("%%$+""&!*%'"'((&"&!((%*%""#$'((#*$(+)(*)')+&"$+"*+)%&&(&#$&'(+*%*%$&(*#$+'"*!##!("!!&*()&)+#!+($%(%'('%"&+(%*%*$
@r1097
NTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGGGNATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCT
+
!E9-/G%!",>:/&00#$."<@(64:$C2;>;').FC'80?<;C+,:>D,:>!*B/=5);7&2-BC("B&;1-&*AH,)##E?@(?86GF/99)?%E4&1'>"D+D:F/F
@r1098
ACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTTACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTT
+
'=4&C@C+186=H;/%0$$A/7;.-1>E)&EH(F6$;)-5)C%7#4E:48EF38BH-FA$;>!G5"2'867C6G$7%(=$.@;5&/@9$&*7=76";D!290E$$-$GG7@19.D.@?2"?4A$:5+%%4
@r1099
TGATGGANCGACGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGNCTATTAGGGCCGCCTGAGTGCGGTTTTACCGCATACCAATA
+
'*($*"(%!#"+)+!'*#)&')%$"!"!%")!)*&+"&%(+'''&'(+'*"!"&(*$&#'$!''(+'*%&*+""(!&'!)&"&*#&(+((#!&*+%$#$($&)#&!''%*#(#%$+)&"%%!#*$$)'#&&
@r1100
TGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGAC
+
7&>/D=FF<G-(@)58+2!32;*-GH$3!//9?C9'.GE+#@2%,-F@D2F2D:'/
@r1101
AGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATA
+
@B/5>3A!?C!9;"D>?!2"5;/&@9+E(2!+0<G&!3.GD+3H/G'GA5A6:"3/4A-63%:G?=2*''69C742?6
@r1102
AGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGNGCCACTCTGTTCGCNGTCAAAGTGC
+
(C=F#3C8),2<H=,<D9.&E'E/(>1-&<!76?%H%?<3*)!??'6+6B+)+@?+1CE'@A@88B(;'A(6F!@F'#)CD#(3HD"ADCE:%>D6G;+$2D;:;3"F)F0!$0FEE2G6;350.%$@&*D2)!53;;$)1"&/C<#$GB#0;"-+E.$
@r1103
TCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTNGGTATATTTCAGCCGTGANGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCNCAGNAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCG
+
B&@8#=;+G?.&(1+E3H!%E.-43.#0B9BC5(EG@)9F5:#@/:?2!A?&=03,06'G'4C69=F;'%!'D%88(*"G6?574>=6F,76/)%:;%?23%><B9B(03A=5@;=.)+-:.G:<2#>.BE3G;@&3/&#E31>-!C8?H8C1A0+%20?28?D9"C5,/F=?C:6E=CB%!,/5;,<H!;#!=+>2?<ED(/&=B)0;CG#%.<#F74BB%>?+;)1)*G?++73.>1
@r1104
CGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGACGAAGCGTTTCAAGTACTAATTAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCNCTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAG
+
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
@r1105
GGGCGATAATGCCGTTGGAACCGGTCATCCCCGCGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCNTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCTA
+
?(?,&4H979(@++C3961B:#7F+92B8E.G938@#08.2;0F"9A84#=@<,>B$.H'G53F1(%H(!ADDD=/+.)&)>@9C6(&D?'(5988<7G>0/;:8<A:@EDB,DCB(/B+)((FB-<><2B,F;EE6$#3BE#;*G">;#A@4)'%@A!A0%7'>9E(B1?1:!&3,541/D;7*B)6FF/)5C>B=)H..=!,0?/),D":@4,H1%&**EBBEA)0$31H"$9&,
@r1106
AAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGC
+
<(<D*<3=';A=)>(C1G2*;A/?97H5%9$D*4-(1C"G5%A.+)(D.;0%DC0"*=6;
@r1107
CATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGAAATGAAAANGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACG
+
B@!1/&/+8FEB*/H%!F*1?%%$17@4/#2*24ED#262(:%+88"9</$E%.FD&A3B:<."F,&/D)@!,9")&!&,9%HC<!$$?D1-/56*?6GH#6=3CGHC4A!29+(1+)-!<C3EH=7*F@2=F4*%9%!>)+>:<A!#HAF7>8:/C/C;A
@r1108
GTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCAT
+
HD,A1?C$.+:2H0*.-!..53%>:#26(GG:9C0,/2!D7./$/'.+%'F+(+1%E@523'7'.?8?@*G!/E7(?92<9D
@r1109
AGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCNATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATTAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTATCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATTAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGNCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTANTTCTAACATTTATCTGCATCATACCT
+
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
@r1110
GNTNATGNACACTGAGGGGAATTCCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGAAGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAGGGGCAAAACCANCTCGCAGTATCTGGCCTCGGTGGTGATGGGTACCCTGCCGCCGCGCCCGTTCAATATCCGGATGCGCTGGATGACGCNGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGATCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTNTCATCTGCGNGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCANCAACATGGCCTGGTGTCTGTGNGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACCTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATNGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAAT
+
#*%%"(%'*+!#'!+)'($(%)%*)$$$$!&)"#!()"*"""((!"&'!")*')("*)*#&))$))()"('+'&)(*'+('')%+$!('+%!"'")%+!$''!!*#'#!$(()!'%&!$'&##&''(("&(##(#$$##(%'!+(+&+!!%&%((!('''''*'#(#%*!!$%&(&!$!"*)&$('')&$%)"#"")$)'++%+&$+(#+%$"(#+('#!(+('%!((#!$#)'$#+%!"+*"+&*$(+(*'"&%+()#"*!)%*+!%%&#"''&!'*))"$"""#!)'#*!("$+)*"*#"#+*((%!+'"&&#&+*+&!#$%"+$$#%!)#!"!""%*'%&")%!!!&'%$%$*)+!(!#('(&+'!&)+#('#%*"!*)"'#")%$$*#&*%##$$!*!!+'!$&&')*(#&&)$&$**!&!'!)$*+(%!$+"))#+'!+'##%!&*'%"%+$'(#'+(%*+"+#)*(#"#)(+*%"+&!&%(%('&)'&%(#%$$**("%')('"!))+#"#"$#)'*&))&*+*!!&(+#')+'!!"*)')*%"%(!$#"%$#*#'+*!$*+'(%$'"#%)"!**$!"&*)%*#%!"%"$'($*$&%'"%$(()&%%()&+''+"'#*%'!*%'+&$$($*(!*)*'!&&""$)'$)')(*'$$('!(#$!(*!"')&%)$*(#'*"(+#'"$#))$%%(&'"!*(*#!!$)'())'"")'+%)%)"!)$$)+#''+&&(($%&&)!(*#+")!*&&(*""#%*#)(!"'$(*&+)$%$+%##%'*%)!)''$"((#%%*'!+((#&#*!*&!+*#'$'+*#%+%($#*'
@r1111
TCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATNAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGATACAGGCCGAAGCAGTAAAAGCTC
+
:G@.!.A%*6*$34H?/14&BH?94<<.=BH1?>H(=:=(4/&&$.8HH&#<>6!4%:(*(88G/1)%8G=?H828!8-8F5*6$"-6;5/<@;#D6AD1H6>72;/+1->D>A)5%HE!)-?0$.2#2==>"@5"D-?/",C8C?E59%4/@>?H1C/$+0F;&!*#:*G/-HB8&@B9H>D>2"+>%;*+>CDGF3E:F(;:
@r1112
GATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTG
+
/A<5#3,(=B*D++1.$6>'C63)4>3?:%)<D)".+8;0,>#;+$#6?*A-3#G-E)7%3.=2<516FH21,;1?$0*,"8F=198D465?)&)&B
@r1113
TATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTA
+
:,#:1">6(%6--B1>&3C02=-,;!-BC+%@4"6=:/0./F7.=<!"!E77*4F$>1)E81A'.:$(9?BFC@5?C
@r1114
TAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACGAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCNGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCNCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCC
+
'A-@B#?9A!.8>??#*=;"."D$C<5/1AA6>/$;%#1/F>'%./-/BA+-8!!DG,A%3?G271==%H16!?+3(#58EG4DF!D#(/@<8C%#AE!?D2(."0+29E$D4+0+",',68GG$:FB8.@42GC/)047)/%B7H#7@'+B84+.,#G%&>1-/D0H10:H0:G)<GD7DFF<1&%!-'%G&%!#($2+H68"-?H=/<A/2"97;(<!(E>6."H79C37F;))5-7-?B$762)F@H9BC8AD25G?3E.71BG)1?H5"4=&#6E;&F:B=?4.G#GF0/1)6,B"=@9#H2/6*,1A3?B'B/',;.*89C"!>9"D!FD>(9(>8;G!',B7E>20G5"%EG/!&:>DB-78
@r1115
ATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGNCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGNCTGCATTATGTCGTGACGGGATGAAAAG
+
CB93+#&>,H$C"+)75!>3D9$*;"<8D-,G#"/#37,+7:0+!G/+0.)22(<A60.A9),85A3#-6-=EA4/54#A4(*7C>#02;+(><'<DC(B4>@8H(?<04&C<)3:=H(G#)%><>*;!A"@$,E<C:$9?>5=).2<18%H-/'."G:*!<"D/9G-H$(.??5!9C>;F>*$+B?1=>&*6;6A#GA?>2=4E#><?E*>6=91E6/*?=>!+-37H$<>D7=1E<'G4;=9>GE#$2,7,7>#/$G1,8!C=
@r1116
CGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTG
+
E='1*15B+&28B3.%%&)G&/$<8'+/<D-0H6F36;2>
@r1117
CACCACGGTGGTGGTGANCACGGTGGGCTCAGAGAATCCGGATGCAGCCGGGCGTTACAGCATGGNTGTGGAGTACGGTCAGTACAGTGTCATCCTNCAGGTTGACGGTTTTCCACCATCGCACGNCGGNACCATNACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCCTGACGGAGGNTGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGNTGGCGCGTAACGCGTCCGTGGAGGCACAGAGTACGACAGNCGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGNCTCATCACGCGCCGCCAGCACGTCCGACGNACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGA
+
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
@r1118
NGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGCCCGGCTGTCTGCCATGCTNCCCGNTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATNCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTNGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCA
+
".$:@;6-D:#A,A4!5HA(3C=-/)@A'?0?>F/48+C%8C'4G"8D?)%;&2*"/1H0"D34.='%/;1A7#?<:,;)=B?D4=,#855$&=181)$E;@&@-67&8"?!6*(F."476#E*10EE>1%&7,A?$/BB74*-#,E=.?!D<4AG;#5>-&**55!=D?/$)A<2-:.D:'-.'72H*1G;C3957=H:D0->3=);:(A!+)<+.D</#8H#4.8!329"2/@F</450&%6;2,"%)>9*D-+H,H6,F#20G/(99&(5)2E!/&'?FF1(H$2#&7&EBC0'G$?#
@r1119
TTNGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGCACCGCNAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCA
+
CCB#.:%G<<)A9!8+G*3:"%>6940%C((#8D33$#*H*C$#>6HB(9#$G:/,9!1*!162&C</$6#H0%1'5*/,.2&/@77@:3&!$.@+)>C6A#&14!>0)(5;6/*=H='DH7";093/A-A1+!$-1$0A?;:(EB/.#C)22!=8>.-G8-2.)H4//0F4*010=3/$9F=%G(7>C=G)?7?,(&;(@'2/-)&(2:C%"
@r1120
CGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAANAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTNTCAGCGAGCGNCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAANAGCACGGGGGCTGGAAATCCTTTCTGTCGACGCCGCCTTATGAGTAGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATANCNGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGNTAGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGTCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGNGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTNTGTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGATGGTCCGGCGTAAGGTTTACGCCNGTTTTCTGGGTGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCCTTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCNTTTGTACTGTCCAC
+
+$"#'#+))+"*+""+"('*"(#'!#+'#($$#+(%#%%*+''"#((+""')(#"%&(*"*#"$+$()*))(%&"))%('(&##!)$&)#"(*(%%*&"&&&#'('#))&$%#!((!!("$%&%!*$&*$(+(*("&("#(!()#((&'*"&%("%$)+%"$%"$+('%*''()$"'&%)&!#$)(%#)%"&&!))+##)#)()&*$(&+$*$+"*$+#&##'&'#*!#$*"($+%""')&'#((+"%#+"%&)"$$'%+#&'"'$%&"+(+"#(#*(!)(%&%%+!(+('##%!%!$"%''%%#%)&&"#"#&''!+&)$*+*)'')++(+&%')$)%!(#"#)"'()'+(+*$(*))!%##($!)*)&%""!+))&($'$+++$#*%(+()++#'!*!%$+'"&(#'*&(((()(!%)!$&%$&"$'%*%!%&)$"")+*&)&('!'#(!("!"$'&("+(+&!$''*"'%()!$#*+)$*#*+*%%))$!"(')"(!(#'()("!*$&%!'#''%)%#"'&*#($"+)&+)$#!*'%)'!(&%'*)")*#$%!'$%'#%#++&'$(%'%#)))+$(#"'&'&)')*+)%)$"'#(&++%'%+!%%"+(&)!!()+"*)%(+*)#%%$""$"*"#+)'%#&%&"%#*"(&&(!$'+!%!$&')+(#(+&%%+%)"!#&*('(#+(&$*"('!'")*)'%&!#"''&!+')*'#''#$")+!))$%##&!*&$'&!!!*%))%)!&*"*&!'(('%%##+)$)%&&)%#!#*""+*#%!&!("'!+(())))%#"(")!#"#'&("##%"%"&$&(*(#($!+!'*&%$++*%%"!*)&+!!#))$&"%'&)%'(#(&%%#")'*$('$&)""))$%)*!&'+++%'+$+'")!$(+"+(*#%!+!!$('''$('
@r1121
GGACGTAAGCGTGAACGTCAGGATCACGTTTCCCNGNCCCGCTGNCATGTCAACAATACNGGAGAACACCNGTACCGCGTCGTTCGCCGCGCCATCATAAATCACCNCACCGTTNATCTGTACTTTCAGATAACACATCGNATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACG
+
#)DB+CE))E6$BC+!!?.A=-*+F3!G#4'E2!-4H$&?'G(!H)FEDE.847##AB2:H2GB6;,'*=%H"DG(<E)B/B+@E/488#!'GA=5,G4,>/9=)#!9502*CD!"2C':/>@E2-.%?!<8:.6;G1/8<%/'C',/?7%4A;';>AG/E<(;)"9:G4*F,:5+;8G7#6*1C1,"@#2*0>(=!85!=-3,=@$CHF!(!)#@CDG3389A&722A-9"&$((DC<,#A0?:(D->!D>!+GAG;9(4426!<<!'$A'38;C;017F07(&F?/"H'3C>@*:G3<;(%-:(;,?59CD*-8'B;0&@?8
@r1122
CTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAANGGGGCAGCGTTCATCCCNGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCNGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGNAGAAGAGCTGGACAGCGATANATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGAATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGA
+
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
@r1123
CACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGACCACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCNGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCATGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTNGTNATTGGCCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGNCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATNTCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTNGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGANACAACTTAACGGTGGCTGG
+
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
@r1124
GATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGGTGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACNAGCATGTCTGGAATGGTTTTTACTGAGAACGTCNTGCGGCCTCACTTCTGCTATTTCGCNGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGNGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGANGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTAACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCN
+
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
@r1125
ATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAGANGAGATTATGTACTGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCNAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGNAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCGANGAAGATAACCGCTTCC
+
0BHC9>-G(?G+CD2*&/DCD/;1CA&>08B6+/C18CA1>#+*C*-8F<D<?-51+)H;B*EA.,:,923:+8&7'H7G%:#C$7<8:>@+8"'$7D1<6'HA(B68*E'E2,/==7166.D#(&++2<,$#G2;A?5!6E?F!1(+2!H$E"!7?>/7)%B..?/,,/%%@F1#2G+1%4<?/6<2D3H=/)@,/AE@9;(17)/'::GDH'B..)B&+!>>=B#<</D2=C')C-$#0$95%H)&'C7?$)<.81'>9D1A<?D$!2D62$D92<+96<.)9,9CF.":"6",H/(5.7%)68*88)C64D&5//FB3$#!<,*;<@D16BE$A<921)D10?$
@r1126
CATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGGAATANATTTTTTCAGGTCAGACACGGACGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTNTCTTGTTGGTTGCTGCACCTTCCTCTTCCTGCANGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGNGCCGCCAGCGCATAAACGAAGCAAATGCGCNGCCTGANCCACCAGTCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCAGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTANCANTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTNGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGNANGNGGATATTGCGCTAACAGTAGGGAAAATGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGANCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTNACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGG
+
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
@r1127
AGGCAATGGTTGGGATTGTCGGNACTATCGGCNGCGCCATTGGCGGGGCTGTTGGTGGNGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGNNCACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGNAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAA
+
:8+?D?.%1BE&D@69GC+'A9#+8A*!0$:=)83F;4D=G+8<8E:E:EA1!3A,:8),':(G(">A11?G263E12'AF@=@;>B<(D;4G(2D9+7>#,*&8GGA59$(!%)'!47!$;B0%D"'3;,$!:F074D@4!)8.:0-EFG/2<=@C)(2?#98%92EA/>-7$0&4;-0E';">(+&7C=DA4"?2<1*13H=,+#E(,,1;=HE$#H8>0@88DBD)(&</B"1:.=0GA";703"0;,4F1;**2A84=?.9@"'(6>8E!@@:#2F22":5=&>BB3#!&@@E"7"'CF,&9*'46"$0C(DG;$$#H*&B>)6);E&BB><.19C84)/A++/9C9).G&@HEG/(#0$@AG1"E.:=5(.%(('6G."@%%1'?'F%8+30>'FG/!E8%G7:1D;>3'382'>&82@H+;
@r1128
AGCATCGNANAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTNTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACNGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCAC
+
A8*@<$AD#!G.9#?%<,@;">E.=E*5$E7F:1.!+E2'FD;G-'GA..HE4!')3A&-"G3,64>C=A33:<8G/@C+)$=(1#-0#)?*/9#85G'%3B&.FD.#@@;&BG%.-B48><C%35E=(:/G@?96GC)8)7)76H#233.#.F@#*::6C=$E=,(($)",-2+0#$#E%H0.<:(C*-2+":85*)B%"+7G++/A7D$(0(#*>%9/A2(-=&0H'*GC)G1(.5E;EDE$E+(E%-?/&9C)(3F6132=-F
@r1129
TTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAANTTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCAGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGNGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGT
+
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
@r1130
CAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGANGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATNCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGNTGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCT
+
34+8$G:2#7)AD!7C:@%;A>GF;0)1@7HA>(7BEF*#,-28C0/=(5<-;;8G3757.&"=/B<9."G52&:?E.E702)?7?3*"#H7-D)6+-#E5%A*?(!&3'7&%+G3)"&A@F2A?+8A&)F?3$<G3>3"H?-@8+3#:"#*/!8"(2,8@C*3B">(*3)4+*F;"@>?C(8>68>E>+B5$E.:C@-A?9A@C;9$&)G:%*75)D%-+7"-H,=9@;.5.@>,49(F8"*@B#D)<6$HB8F0HF@<5C%&F583,'#";340H/75C"'C*G:":"0CD)E">1AF&-A=D':5,;F$H%D3#4C4>C2'D$7(!(H,"!(*::HE=,!/&%213>8B,+,=7#)35&@1)=&3E7;:D@-G*+$>B62;-4.+#:E9'>,A31H2F=34E)BCCF6,FAF6.F,4+9*-&1%6
@r1131
GNCAAGAGTGTGNATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATNCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGGAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCNGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCATGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGANGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAANTGGCCGTAAACTCCANCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCANCAGGTCAT
+
($#'*(!(%%&$!$'+%!$"**!&'#%*&+")'+*(!$+)*%+&$)#)&&%&#"&"!"*!#$*%*"&&$'($##*'*"#%#)++$#$'%*$!#%*)'%"*!&%&)%*)'%**(&$&*&&&+(%+$)*%('#+#+#$)$###$%(!*%*#&$*!"+#$+(*&!$*%+""%*"*))"#$)(%+"*+&(!&*%!$)++#$+'"$%*+"'+(&*$&!%*%+!"&'&)(+'$!&$'%#"(**$()()(!$)!&%'&&'+%+"*&!$'+%!#+#)*+%("+'&'+%($#'$#")$"'*)$&&'$!'&&&&("*"!(**(*"#)$(%+#&%!#'"&&!"(#(%)+*&&(%("$$*&#+#$("!'")#(%%%#"*!')"&!$!#&+"(!*!&"(**+&))!+%""&$'+"#+$*&*!+(+#+#%(+(&%%#%("+#"''*('$+&&&&'))($!!+!"*&#*"&)$'$%&)&$*$'+)'"%(&%%&(%)'&$#%#"$&+$&*&))''%#%+&##"#%!$$($"*&$"*&()$"$)+$)""'$#'+*&*&$*")'()!"'+#)$$%&)(&+"')$&))+)(*%!!"+$&"%+*$&*#+!+!'$$*(%(+))#(
@r1132
CNGTTCCGGATCCGGGCGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCTAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAA
+
%)*+$'"'*"#+++)#%%#")#!)'%#"(+("'*%+#$(+%"&&**%+$")+%#!$+'*')!&+%(+(*'('(*+'("!''#'#%&(#&%%)*#'&!*(&!$""!*'#&&#"()+
@r1133
NAGGCGTCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGNTTTTTTAATCGGGAGAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCNACTGATGAGGGGAACCACCAAAGACGNTGTTATGAATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGGGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATNTAAAAAAGG
+
#''&%''+$$%&($"&+')+&+'$%!%')")+&&%*($%"+!##)"&%#((%)%)&#$""&+&%%+*)$"+*"&!'&'#(+'')$)&"*!!+(!)#+$))(%*#)!!)#('('#")'(!)#)&++'(%")!!)(*)++*+"$'%(%$+&**+(+&&!)$$')(+$!'"**%#'%)%!""*"'*$%!+(#&*%+#'&)'("!%(%)##!%$*$!)"))!&"!&+(&#)(*%+!)(+$**"))%%#$*!###+($)$!("""#*%*'&+!!+$(&&)&(''#!"!%#$")(""#'"*&%*"'(&#&&$(&)'&(
@r1134
GGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTCTGCGGCTTTTTTTACGGAATTTTTTTATGTCGATGAACACAACCGCCCAACTGCTGGCNGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCNCACAAATTCCGGGACTGGTAANCATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTTGCATCATCATGNAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAG
+
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
@r1135
ACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCNTGCCAAAAATATGTAAAATCGGTGGNAACNGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATACCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTGACTATAT
+
?"C+=0/5CA?38'()9FE4D,:486-D@::"*+=E'@'9??,76*8$,5.E4#/--;5'18$4(*8'/95>8!%.?,7F5$&!&/)80#9%#(*.(?:A?01.FD0C2.6/1<*%:=C?DD5>5)-8+A#$(,:-D,#?.+*H?F9."?-5CF8*B<)?<.7D4B$(!4:/5/'(&B;,<1:>:A%CC!.@#//A@5?!;6#C$&:;"4+2&#E0D;)&G1/-&(##B@)/,>)4<5=%1D+E8=;F=262=-&%:&*+@/9%GA38"2;G)4<%?
@r1136
GCGAACGCNGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGA
+
$&&'*&(&!+(!!("#+"#)&"!('+)#""$'&+$#$!&&$&)#&&+(!')*"(&&$&$)#'#!+#")("+!!'+()+($*%#
@r1137
GCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATNCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTNTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATTTCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGNTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTAACNATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTACTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTNACCGCTGATNCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATNCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGAT
+
G,/E0@((B.E.0(+#GB"6"7!*C!B-7/1>%?)&0$AG6)9.>6H%9#D2"G(G;8C@->2"7@'G<06HA8&H@$($C,F(#%'!>0>).'='>.(E*;+EG*E2HD=15.F&HH4!&$C:+26+C9,'((90%@7B%,8,"<8>4%B:$E%<E,8G3E4=:9><(71/5;:>F9)D(:/?A<H+E*=+)G8D:*557G>@BDFD8-=6",1$@+6:,:?1,+>.:543%#$0"<BE!HG&0027.::;2D//.=A!G%/;-5&4#"F=(HF;<F0/2<*4&;;%?7/(E?H%,FF2=/1B.=((3@(?-3",F8H$719$E"!)+48&%<2+A@E,(<#3<"E/-=8F<;!<"@'$E#&"3@E::G8A452D*#D/68"5DB=$F-EEB0&;-H/!!$D2A1F?:CE$,F!2H97#F8G#+G19+&!)/"7H!(&H8%##:$=:=6-)1D&2@G)#!3#C(;/E#2"6>$:B&%-5H2"+;8#/*@DFD&/@=7@#<G86,::')/0'9>B"B/!H77D)CFD$'&(1(">?>7'<6#1'>(E-09EF&7"$ABDBF'8H$G;%*C(@>'G2.7@A:'36=/460-D()@>H-)7-H)*<(%%:="B=>)#4DB@,+A%+>)HC>(1B-1/<")9<$+"+F@(D4&4/>DG.F22>054&E&,!/=+?A#))'&5A(0$*@2BC$H@@/:B=55807-C5'"'(?<5+!*5)=<$BD:6@G0/DC'!3A;5:3?2AA&:6,-:<B-%F'GDD:8"**A$CB*;;>@&B0H#$-8>4$'CGG'"019:?"8@&>&%.!+&"3#%D:.?&;*-':0H:C*67#!,/'*!EC0/%D>&GC-4-(*.D1;H-5"+6B'B2//F&73<.@"'B%/=F4,;D"%10"4A48&&3=<9,?D=)'.AD)-"@7/#'C="<C3DG.,),+,!@;8%EE#(8+*"5HEB2=;(),(#H8B%36CE=4/$9H$FC#%>,""-#>EHA&G2)$5)417G'>G&<%A/%F?3DA@C?985D*+4F/#$G+$)49=#H1)87/',(&2<6C1#.".8@%,%7*BG%,#/8A7@$$&:3:1/49#//$3/!3?::=*-4->>A.G;0C+2=41F$-8E?C>E8'HG;D+B7?<!DF9<ED/7#++EG":+#0)BE5);0@'%,=;%=4!A>>$?%9;E+6F,"&A!),!E?G).A.8:'+>E-!#E*G$@<,06G:86@1)#:E?;8/;-:3&828*="!'EG>3:69=G783/'*-A('&&&-F@?-:@:,3=!G*82:?DE<=?H-F/$%B0<'(?:;2#(4@+22D*,1@!7(>B'A:&G?0(H+7G462=!C;+!!47;28*=(@#FA#4-&,);0"!:+A1+62#)/6.,4#4075B"5+:,@0>?+6B64.C"8:$>,<+'.14DD9%#A;BF(7
@r1138
TGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATC
+
;,2-3;8)3(HE?-#9D-7&AA.F$-+;75;A23>2CD#=(64/
@r1139
TTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATNAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATNTTCCGA
+
''%#!&(%+&&!#&!+"$)!)*"$$*"'"#'()!"+%"))""&!%&%$&#*)&'%&&'")%"*!'()''*'(%&&$!*(&**)%+(%%%&)$""*+(+$&"$+(')+*#%%'"#+"")(!
@r1140
TGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTTGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTCTAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCNTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCNAAGCCGTCCGGCACTGACTGGTCGCAATAC
+
C1?>1(6:8+G<E?&G'C4GE-)B"'**";?@%;,%&#?.3A(=C@!&,73D$7+F'<#G6-.+9AD3"&'7A9!!E&=H<:*@@.,"055/+,=.&<%'E:'112G8761@>.BF&F*?F)@B2C"E.#8:B<#;/+9)&2)<183)>$;=H?*(,E3?@1$%FD26?8*.'5,"2=1%A?+/8CA3HH87?&1:C"F"35H4-=;G:<G/$4E-&8-A%(*)$;,@85@&B-6)$@4#7:3'857"=:*F0@:)A?E/EB'18)'5(5<?(@,%H-:*3H9/A>@!EB5>(G7A@4/B*(8>!9-@C''/2&&1+E!6C97:D:';@5G85$4AG;HE='5E6>7(-*%@.:&&.4>>*25"E#,'"/E'6GDC&A.!;2254#>$+0!B/?2"H!+>76+>0&-E6-(A:B3
@r1141
CNGNTGAACTATTACAACCCCTACAGTTTGATGAGTATAGANATGGATCCACTCG
+
(%%%$"*%!&+&!)'(+(%*(#!"'+$'*($*(#+%"&%"#)"(#*%!"*%!+$"
@r1142
AATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGNGTTCAGTCTTNAANGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCANTATTCTCCTGAAGATAANAATCGCCAANTAAACCAATACTCAGCTTTACAATATACTCGCANAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATNTGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTC
+
8?G-G4,>>,9#"8'.F;!=.9,*$E7<'C.$F:E9D9.H!A:(<#G>&!H@=>74--B*0)=B=<=&:03/"*18=E7"E8@-$DB-27+2?4&<CH!9,@/2/#B2=5EBDE??.&+'7.=/E4#/C%9496<?%/2#$>(&=!3>43518?%-1D=5#@$B+!H7&3<%=1$6F0#5B$*1(,0.A'7=%'7B20/246'0?D%(G;*D8-*?%D4E4"*95'-AG'='$&D395:*7>A+#+CG&1?'/"'@1/)=7(@79A9A=0D+9:HCAGG./%6+274?*#&'##G/;6#55B5H,C+2+1+0H:H2HH#@@H)E0D6)(+,<2,/'=4CGF!-)?B,(>+5<#CHB8:$>%1&7&@9=88$A<!87>*##>8-69G88?7%:$&.&,C,D=8H"'%6E3/"3":H47.53C2<FBH)."+&C1GD!3.6(!4".(A4)(G9H7D@#*#A&H
@r1143
GACATGGTACGTTTNCGGTGGGCTATTTTCAAGTGANACCGGTACATTGCCGTCNTTGTCGGGCGGGGATACNGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGNACANTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATTCGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCAGAGTCGGTGGTCCGGCANTACAA
+
(?/4#,(/H''C>%/;12D/13@81>=9?##:@G%!+%>2BG>8*$<$C,&D9,9,!6=>;E!'E+7%4:.3<&,7#5*"@@@H<'.566:E7:BHC>-%,>B$:%9F?'E3H&0<%=H.2263E,@1'5#$5&*#4>B*E--/AE.?'C(76999.:=>E#=3FHD#17<>$-'!G)9C8'1/';E;/H%2GF?%-C@H'CE-3&<';'7//8#>&:(7C%6/<7BBE:B?1$5(&22>89@""=54H/F=4",E8F:/<A/@=,DB#5G+B2=(H%<2*9//$E>&00@DC5->/%;C;#GBCA6B(.:C=1;#AH#6&<.F"("&&
@r1144
CCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGAT
+
H%&7>;EEAH!A:0D=6*>7A(79A1+)@>)58<,G%(95?7H!,5(1C9H#%6%7"$/%F.E",0H@')=';B1:3!2(*,4"/98<G.>&1>(H)@8EGB+)BA+*AA5;/HD85G2'BAC3AF3/HB06FA(<3<B,+)&@!<&1@0H#3';B(27&C'FE39#D0724E)%A2ED-;$-'+@H4<B>&H*+>AG#H0!1)2/,."FE@#0F.44A"%G/.#=
@r1145
GGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTGCC
+
+-7$$A4E9?)/<)5&A00<0;:@&@!*GB#$:$!%"!''+%H75"6B7546E<>:2E=&F*7:,5;C6C)'&'&:.2A2CD'A-3<G"0F+#$F4E/25.C2!43A/46E83/0+E
@r1146
TCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTNGTACTGGCCGCGATTGCAGATGTTATCGACGNGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCANATTTTGCTACCACCATGACTAACGCGCTTGCGNGTAAACAACCGAAGAATGCGACACTGACGTCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCANGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCNGCAGGTGCGCCGATCCCGTGGCCATCAGATANCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTNGCGTATCCATCGGGTGTGCTTCCTGATATGCGATGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAA
+
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
@r1147
NNACNGGCCNCCTNATANAANAANTNTNGGNTCANNTCNTGTAAGCGTCGTAATTTTCTATCTTTNATCATATTCTAGATCCCTCTGAAAANATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTNATTCAAAT
+
&#"'%#"$$"*($")&"!%&)'('"#*#$#)#&*!$))&$"&+)))+''#+"#*%!'!"(&$#+#&!%&"##*#'$%!*#)"%%+*+'(!+$%($(!*$&*!!(+)%+')##*"#%&+%*#$&*!)!((&((+#!'!&!(!!+!#*$'(((&"%"+!
@r1148
NTANCCCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTNTAAGTTACTCTCTATTACATACGTTTTCCATCTNAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCNTGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCNGAAGAAGCGTTTCNAGTACTAATAAGCCGATAGATAGCCACGGACT
+
"*(&+*&*'$((*&&++&#'*)%($#+&$($&)+"#("#&!+$('%*+'&&'+++(*)&!$'!'$("&'(%'"#"#'*##!!!'($#"(##&)&"&+&*+#%#*"&!$#&)&($(#"+!"&+!!%#%$*%*($&$#%)('')&)'%%)'(%&#"#'"(*(&$!$&%+*)*&$&$(!+)+(!&+!!%#$+*!&)(+%"'(*%'*!'!#"%)&(((!+(%)"+$"+!(+(++$'!#+(!'&$(*$#$+#%*#""%++"!)&"#**)&&!$%*)&*!('!+#+(&*'"!"'+&'"%(*'%#!+(&#'!$!+&%(!%$'!%#
@r1149
GAAGAGTGACAGCAGANCTGCGTAATCACCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACNACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCTGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCGCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATACAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCAAGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTCCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCG
+
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
@r1150
GAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAANCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAATAAAGCCTGATGCAGGTANCCAGTGN
+
@*.+0E)/@+H":-8F8?#CG?!.9;!#"8G#'"":;:>'0'4&>3>2''AC##<?=5F)-$C$#A0:G=);H@)/+2/"D%?2'%8*3%<E*#8%-"%,=F:.$6<2?++82
@r1151
ATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAA
+
46.$C"#.A,21>:7G"DG/@0@9%A03=988#3*:90)?"-5@?<88:.;63,+:E(4"!/';5@()'
@r1152
TGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAANGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGNCCAGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAANATCCATTGTTTCTCATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCG
+
'+/57A?C0H/020C,@875E88.!D/1)>"@*H6%!-;)$,D3/D2/CC17G'-A70>?%!E/7,688=C;7EE53*2*0)!793D?HG@A3@#.>6B%=?FC;#.F3:9&(/"#?2=,'/$79F;;FD%>&=?04$4DA!,$7!F#!9'=3,6+86"$>,"+#9@@(*"E3""357;DC/%-%CE-E=!7H.+%D!??@(-:-'!$%#(/!B#E>$0=:?3)F(<%D@7H:!%199:A;08-9$E!8B
@r1153
GCTGCTTTCCATTGAGCCTGNTTGTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTC
+
*;0(1C163*/44"B(>$8$B3@6=1H0&F%;5"%(&"3A*@-8:5(9!A!8;@0<&&3F$+4<!4!&-$<1FB63@
@r1154
NTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAAATACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCC
+
%$(F$).";A*(&6A6"C($B2-3;H575&8-:;D@<(99D>-9A<F5(='1G3BD3C#F1?.<'.E).;-9<%)5'0='9B;:00D8;2%%4#;%BE?2?<#'CF5:>>.5/,)(+-3)489/92A)*!/B(;B9@;D/D#$.=+#,2#"F%)*E//?@(4*!2;
@r1155
NNTGGCTGCNCTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCNACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTC
+
$'+#$"$&$(!#*&(%)&+&!"*+!(*+$+($%"$%(&%+'%+(($++$))(#$'*#+&)!'$)*%&#&(#!+&'"#+*$'%+$!#"*'(&"$+)+'()&)&#$&
@r1156
GCGGCCAACAGGTCATGTTNTTCTGGCATCTTCATGTCTTACCCCCAATNAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCCGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCNCCTGCCACCCGCTTTCACGNAGGTCATGTGTAANAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTG
+
?,.H@/C8<C8%:+GGF*+C+(;<A"5C,C8H?#&?#.;"9<./G'G,@,H#A?);EG84B"*?-,''8B@:1B&3&@F5?:E.B17-CE?!@0>:/#'F=*$-D5<377>,F6%6(41%%7#E68:7(/.2*)?;$-$2(#;&F:0/3%E26#<'(;(>%!422>C./=FB/:/15A11'(&96,E8?AH<9+G6#"$)6'E7+*C#@;0*19*)<?*H=8GC)49"--@A1-B6C',C729H32:>A5A*?$.<E7:795.3-$,*8F67)C4"?5':<1$+#DBG
@r1157
TNNNAAANCNTNNTCNGCGGTNNCCNGNATGANCNCCTNNAGNGNNANTNCANNNNGGNTNGNGGNNATNNNNTCNCANNNCCNATAATCNNCNNCAGATTTCGNNNNNNCNNGANAACGCNGNTNNACNNNTNNAGNTGNNCCGTCGNNNCGNCGGNCNNNTCNTNNNGCCANNTNCNNANGNCCNNANGAGNACNANNANNNNGNCNGGAGTNGGGNNNNGNNTNCGGGNNTNNTNANTTCNGGTGCCTCNNNATGNNCCNNCATAAGNANNTGGCNGGCCNNCCNNNNNNTTTNNNGANNNGNNTTAGCCNCNNANNTGTGNNGGNNNNCNT
+
!"!$"!"#!"$#$!!!!"$"#!"$$"#!$"!""#"$#####$!$#!#!$"$"!"!"!!"#!"!!$##$"#"######!""!#"$"!$"#"#"$####!""$#!!!!#$$#"$#$$"$$"$""$$#$$#"!#$!!#!$#$!"#$!#$$$$#$!!#$"!!"!$!$$$"$#$#$""!!#!"#$!#"!!"!#$"##""$!"$!#$"$#$!"$!"!$!$"$"""#"$"##$"!$$#"#$$"$#!""$#"####$!#$#"#"$$!$#"""$!#$$$#!#!$$$"$$###"#"!!!!#"""#""#!#!$"!""#$$$$#$$##""###"##"!$"!##!#"#
@r1158
CCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTNAGAAACAGGCNCTGGGCATCAGCGTGGNNTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTNTAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTNTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAACTGAAACCGATACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAG
+
(?+6<*<@(59&;,.?6!'H/;%89?<"=AG4+6H?=@+5&B@1==>43!3;/03/8"*(!<(E-)858$8"%'<.0B3/98>/%:(8164$?93D7?1C)94>*)=)A6<&<+F0!6H<?(+>,&1?9(-B)#0-"),-G-64-+@"E<)2B&!)G*#&3$#8A#/?9(1F>=EC>/20:A4)>76<@(C,BF;BAE;3'F8+,1<&.3C%;3&6>-3#>=1?%H>100!.4E!*3F"::4./$$=*-FC/#8056(''$11E-D?$+"+&%;-4@5"7!0711;-1@.6#2F@;H:/C1;72824D>14@E,=6@,4**/F9#>D
@r1159
CAACAAGCCGTAAACNCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTC
+
<1&0C#D%A6$G+3/>6;$=.18-:.."@:!C=127-B@9%C@>;(C:)1&'?1
@r1160
CNGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGGAGAATCATCACCATGTTGCCTCAGACTTGCAATGGAACTGGCTG
+
&"B.&-6-<'*64.32(15#<$G!E"%'B-F?-(H'"<(A24+55-4*%!@D)=-C3/!=<.$;)$3?A4E.%51!EH'2..1?B+/>65/EGB"F5;%7+G>"1HA5A9$""D5"3.2+C6*(CFC0285)#!5DD8/2;?/*BCG(<##0&.6EG'CA*$=0'#+/3>55/$G/A90+%1":1&6@/-(AH8CB,9&A@$?C2#<%&$#@D"2.'56&&01&%B-8>!3'-E*GD=49@&H)G'
@r1161
GCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCNCCCTGAACATGGGGATCATCCCGCCGAAGGAGTNCTTCACCTGCCCCCCCTGTTGCAGCAGGATCA
+
2@=<98,GH/=#-4<5)-*#4&64,)G:!!5HA;<!G6DH@4<(A(5/A;F%A+-&-"63=?,G0<E$):B%5F!C?=E22;'F/+-3''3,BD#11;53.:43,'07F-4
@r1162
ATATCCGGCANGAAACACTGAATGAATGCNCCCGTGCGGNGCAGTCGGCCAGCGTGGTGCTCTGGGAANTCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAG
+
1B=,+3$;9$>-")C6%7,B01F10?1;>!@2@@A0:#&*.?##F366C1D-<AFG8#15)2>C/B9$932/GG;9GGB,1==7AF&,2D,3A0:GFF6"!&=H=3;:C(,$*B(+
@r1163
CGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCNGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCCNTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGG
+
3B23,F@A&5;=.@96GG&C%(?#).!<,9!F$++65.#99<7B19EF&&<?'C;GG=(&><A,*788G%H@;3&.H<.A209"-4=#30>D,151-7"2D?5HC(F615BA=:."18?B'E:?$A:=
@r1164
ACATGCCGCCTTGCTGCTTTATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAAAGTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTNGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACNGTCGCTTGGTCAGATCTGCGCCCCAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTANCCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAA
+
'DH(AH*((';CC$52<2'726%$#D97>450=BA=7',H=3+F77+:7881':F*,-+68DB9<)5'D-%E"C350"&=$;5<(-,A%>59,B@-HA0/:4@)"G!37*31F@:G@@#4<7=34':E*=3@8-1/15'#!68G<F:CD'4?<'13*?24A,AEEB''*>&)C/(BC.B,FG-?6HH5E&&=@E*CF2074=#$=*)(9=0F()"4,8'9+?%@B*12451,B#114+*!$9H@G(20.@,!E+?0G#)8A)2G"=B*F.02=(
@r1165
NACTCCGATTTAATGAACGCAATATTCACAAGCAATGNGTGGTGTGCNACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCNCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCC
+
->##67G=;B3.$A2=3H:H(6,$(&>!;*-'99+>51'&.3<;B>-<H3B+,#,*G"F@8=%3,?@95>H+*?94*.225#-H).E")EC(%7#G5"8"("//?H="6%H61=59@9:@75..,;78@;-A914#;33B.&2H5%H
@r1166
NTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTNTATCCGGAAACTGCT
+
##,9>2.46/1-9E-A.&$('1-9/".(#AB1=<;1!"H0B3F@)1D2(,1(9
@r1167
GGGANTGNCCTNNACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGNCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTGATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGNTGCCGT
+
$#&%!#*"$$#"'(+#%(!%!**$*+!#*'(($+!)"!!&#&"#"#+*%*$)*$$&(#)!%$$&**+''#%##)"%(#*'*'(!(#")(&%'+*+##")&"&&&+$#(*"'&)!%++&++"$#*#"(&"$)'#)!*&+('+''*$'*$*%#"%&#+(!(%$$'$(''%!!$'*((&!#()(&"&**#)##&$%'')$#)'''*("**(!("#+$"+"('$)+!(*%%))'$"$'+'#&%(#*(()))))('(*#&"*#$#'"!(#!$*%
@r1168
CAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCACAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGATACGNAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCANTGTTTTCTTGTTGGTTGCTGCACCATC
+
+E)1.B!9.,#5$>0'86*"%1<,B;3#11A/A;<2C9>%1!>F#86A*,(.0+:@AAC4)9%#@A*=GE+245"6"01($'F2/*((-A+&B/GA0:<D1H"B1C@8E8$8DE"7#."/#?GAAF<"#(+9.>G,'=)0!.'C!=7$;8B<CF1;A+?&E<$'#BB!:D&D&<*9'4D-=EC=C*0&CC"7>$5D30+'()$8$(F8!2-!<H:>G>G5/4H*<4%C(,H@'6/6)H0?D7!C'+<A#<!?210C>4:-7;70G1"0:#08-GB4.D4.4?7@%("=96A&)?-/%/E7;(@H-9,&$79"2E?CD0$0:.?0/?G"FC0?:D<,DE446;>@/!6A'<&BFE4A!,*F#=
@r1169
NCTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCCAACTCAT
+
"*$%%+#$#+#"&%&&#$"%&($#(#$!"(&%&#$&+)%)$(")*+!!""!$(""*#++*##''+$%&'!&''#!"#'(*!'!(&)"!'"*("#))"(((!*
@r1170
CAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAANATCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGANCGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGNCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAGATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGA
+
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
@r1171
GGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTNGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGG
+
79C;%D<$),+")!#B+'>;)?.0H-0(@;'C#:19);A6,>F1%;(EF82',H832E$@GG0$1.F8A='><;2%75<E1;4>604F@>2/C0;"*58&:)<2'71G@?E<*!A%0,&,@#046C&9<.:?B><1#8:3#)@:&<78DG&C*+<'$<5HC27+;@?%.D-#8'+(8@/)%#<9/<8!;E#/39'8!;+#
@r1172
GTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCANTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTTTGCATGGAGACAAGACACCGGATCTNCACAACATTGATANCGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTCATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCGTTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCTTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACAGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTC
+
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
@r1173
NNCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAGTTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGG
+
"#-8C@>9)"H5!&!8AA8"0+D5-7G@$9<-0A7G0GB&8#(/+=10)@B6!:(5(#10=.><@:)A)56/#!(>FC@="DF/D/(#DA,:6%>/&H+#6"#6D.$?G6=!*096?=>H,(2'5&$<@$H6AHE#+3''==/%#="5EB""/5<5*DH*)<A.!$#&,BHD&(5@12<2-3=?":%05/3+F?,":G;4E<E8(72G#5@6:B7/(6?.+D.C.*F<&)/$#'-&*;$.1?
@r1174
GAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCACTTCCGGAAAACGCGGCTGCACCGACAGGGGGAGCCCGTCGAG
+
8(35,$$&H<.E8$4'4B)D8=*2&F?72;))-D?,;C51">G47*F&16;&@B*#,,4*5F3<68/6@%.AD2&!5"G9;G,87(H0)H$>$#&7223&=%?@?3.F1#73B6A@0$A33)&'F)11;0D1"4:74?<F8B*@6H5*<=E)6':BF009:#68"B1A!)<#+DB6%5E402?#@14,F:!"7'
@r1175
GCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCC
+
>)FB8&396@E6F8@($>(@$BBF5&E.&'?3>/5C;7H#046B&A%<.8G,4-*<@;"/3033>=+(@3'!.B,$3;3*+H;85
@r1176
CNAANATNTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGNGCGGCGACCTCGCGGGTGTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTNATGTTTTTATTTAA
+
%'$("'($*+!)!%&*"(#(&$#*$+&'#$#$)&#'+#&#%+"'&('$!"!$"(#$(&!&$$(&"+&#+'#'"%&#*$&++&!%!($*%(&)!&%())##('*""%%%'&"%(&!$*+$$!+'+*($#++(&#+(#!$&*!&)*""#)(#+("&%'$##$+))+"'"'*"+(#%"'!#*(+
@r1177
GCATCATCAATGAAAANCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGNCNGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCAAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCNGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTGTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGGAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGNGAGAGCTGTCGAGCAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGGTCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACNGCCTTGAACTGAATTGCCCGTTTACCTCCCGGGATTT
+
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
@r1178
CCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATAC
+
&>;#"AA4$@)FBD2$0"A<2)<4/74#5D<#)?F;FG?@:6:<$!63=/A+;";?5H#,<:3G(2321"A'/-)02-/'>%.F#H!@+0
@r1179
AAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGNACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGNACACGGCACTGGTCGGCGTGCAGGTGGACTNGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGT
+
-(56/?1*G?"!*D=9!#F+0;#F0),D1!00>DCB('H#A;,GB=,3=D"+BG!5&!@5;.>B+($73?7F*-6C%+>,-=#5#6:4@2='9:;B9=G?'(93.&:F1+4G#/B6+5BE3DC4&>G?(E<<,$0#"+:)/!#"+01DD"8%'C4C673&3E,>*94C4!%*0C.D;&G..6;$1A$,F8$E+&;A5+7;A+B:72*+F"0-+50%3--!F=;&!'+!2EA461>1=>-*//HD%8!/=>@9%BC:6>1*"H4&+&H/GD2;9*<.3(?:,2#?BD5"(>+6*;3-"B9&/B9#5'<&*+3EB00@>,*D..1)(55D$A!/H;@E%647GE*4;'A7=)3$%-)8
@r1180
GTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGNATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTNGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTAATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATNAATTANGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACCATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCNCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCTTATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTCCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAA
+
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
@r1181
GAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTNCCAATATTATTTTTAACCCGTCANCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGNCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGGTGGCATATTGCTACGCAAGCATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCA
+
6C+8=:;"9E14-5=H<G?F))<H;D>@@D+&/H=:3@DA.D+:2A<H$0B4.(@A@$E.92@!?15)0(0#02;5;8GA>A,A,809!B;(E9><3053-)>F221<3-9974/&A%>7;G.)$0HD:6G;29D'FB4E55A@5#H5/,C/DF!$1B<E?G&5A$.5'9AB6<GB3-17>BF:,<2$=-B6?($>,&(?:?)AH4:9:=4645D&&4''DHB(DE1-2>.C2"&<7)"()F:64+3/"F'96EA$"*A*?(53E>H"$&+A.55'B9,EG.<D41&B>H>@CG9A8#"->3"D028*--=*=:8'5"3#:/&-?=BG(:@$3F/@88#H%2*&H&E@C=!/9
@r1182
TNAGCNNNNGGTCATCCTCCGNCATGTCCGCCACATCCGGGGAAGCGGGGATAACNTCATT
+
*""$'!!##!+"#%&!"#%++'"!+$+"%%+&&#!+&('(*&!%+()%!*'')")')&*"(
@r1183
CCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTGAGATCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGNTCGNCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTCNCCACG
+
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
@r1184
NGNAAAANNTNCATAAATAGNGAAAANCCGCGAGGTCGCCGCCCT
+
"&!'"$%%%*!%'+*(!'+'+)!%#%"*!'$*)$)''"!"$'#$#
@r1185
CGNATTCNCNNNGCNGGTGACGTNNTCNNGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATNTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTNCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTTTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGA
+
%'($*%&)#($!*!%!((")*$)$#"(!&++)+)""(&($(()$*!!%+$'#+"")"+&$&''#)()##(!&)""!"$&&&'$(&)+"))+#!)%**$#")")'%!#&%)*$!#&$*")+)%$!&+$!*"('$%+++&+(+''%)()%##!*)!&(!+**"(*'++(+!()($(&)!#"%"&)"!"&)+'+()+"&"+*#$$!*(+*(!$'%#"!++"'$'%)%$&(*+'*!*)$%)$+!+!($)%+&"!#'!!)"!#%((%&))(#)$!%(##"(*'*!"+&*&$('!#!+''*$&#&)*$(!(*""!#&%*)%&((
@r1186
NNNTNNGCGTCCNNATNTNTNNGNCTTNANACANGNTNCNCANTNCGNTNTNNGNNCGGANANNGC
+
$"$#!"#$#"$$"$#$"!#!#!""#!$$#!"$$"""#!!!$!"#$$"!"#$#$$##!##$#$!!!$
@r1187
GNCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGT
+
'"3%%7*&+F)!"A!B)29:'@4ED:91=112"?A=9C"2&7FB>CG55$,+,4;>>1&;*3:A3=1&>4F%7#B'E26>C$!G@&G1#619?E8!%&469=<H8CH1FFD:%/)=1A:@,C8>541:"D32AC5E1E%0<3=)B<
@r1188
TAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCNGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCNGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATAT
+
;2$/F3B!'<<A6=*48@F!(A1#3+"97=H?"/*,>:,B1G!=7.A>C(:/5896=8C;G=H.2<ED&G5&=48-2H:1'&"#F42)7CE=:%-=9><1,B0&4@60E&#9/D2<5-G8B0=$3C8$D(#D(A'-6&@3B;.,*?F/8B7C%?B->%G7G*/7>.-;02/?1('047*9/;653(5>*=:%3#:"(5D/:5;.8G.-&CA)++E.5%A85FB;D,$-2=)DF<7;F/!3&&:"3%*:,68AE69B0;7&='9:<04,9D,:/@59C$7<(7G'&)(BGC0-.6D'11*G;B0G$%>D6&.1;A5'&**A-
@r1189
CTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGCGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGATGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTG
+
41'+B8'5/3>37C:#E9A&-E5C.%3"63+4.%F:-;+--B(E0$8-"1D*@)*;9&4*F$D$.+0F#/*;'0D*4?E(8:."@0CD?9.!B%/H78A?=@+67.B-F$B6@+"+1),6)!3*%@AG.$<+#"D*<+$;8)7D59<.H!8F;,*+D)@7'73*B1.'-5?EC-$?9)(+/;,!7-F2%E>,8%8'"BF'#*((,4;:/<.2.&%?!(->'>$:1)#?+H,5F6@-'06:=2
@r1190
CGTGGAGTAGCTCATCTGGGCGTAATTTCGGGAANGCNGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGCCTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATC
+
..F@!59"8F5:(AF,+*H6%%04&+3%&>8#E3HB7G,80E195$.F/=6,A-(::53B*",7D5*374;'0FA24HF<&<-%H-:HGED@'$>69@0@2E77,;=@-=5688>$GGB<+A'-<:&%<H6:C#8'E<)3C+&0E=@HD0=)37
@r1191
TGGTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTAGNACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATNCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGTTCTACCTTATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCATTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGNGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTNACCCTGAATTATTTCGNTGGAATTTGAATCAATTCNTCCAAACCGCAAGAACAGTANCATTTATTATGCAAAAAAACAAAAACCNGATTATAGGATATGA
+
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
@r1192
ACTCACGGCTGTACCGNACAATGAGTGTCTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACNTGTGTGGGCATGANCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTNATTCGTCGATTTGGTGCCGTAATCGCAACTGCCTGGTGTTTTCGTCCCGTAATCAAACGACGACGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCNCACCCGATGGATACGCGACAGCACGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTGTTCNAGAACATCTGCAACGAAATNTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCANTTTCCGCAAAATACGNTAATTTATTTTTCGCCGTNGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCTTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGNCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGNGGCCANTACAAAAGCGGTGTTCGCAANCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCA
+
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
@r1193
ANANGCGNNNGGANGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATANCCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACANGNTGAAACCAGCTCGCGTTATCTTGGNACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATAACCGCAGTGTGAACACNGGTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGNAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCNATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGANGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGANGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTANGTCGCGGGTATTGGCCTGAGCATGGAGGACACGGAGGAAGGCAAANTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGAGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTG
+
$!(")&("&*'&&#$+&(%%$')&$))#("+#+&('*("$*#+$!#"((&&"$)!#&+(#*!(&)!$#(#(+'&'&(#+#+'*(%((*(%*('"(+"+!"&+('+'$(%#(**&"&'%($+%(*+'!&$%!###"!##&#+*$"%$+(!$+$$)&$((!')#%+((+$*&+!&"$+#('*)&!&'+'(*%"&#""#''))"+)')*#*!*&'%*%#"()#!&#!'"+"#$!!$+(+'')&""+"+"*#(%+*("'!%#&!#'$++)$((+'%!!!)$'*(*%&$!!#"((**$&"'+'"%$$%#*'(#&)("$#)(%+'(&#'+$'***++'$)"'*#!#)'%"!+&)(%+#'##!("$#%$(++(#!&$$%%)&%&&##(%*)(!#)#$$&*("!(!&"$$*!+*"'*$&+%))+'+%'&("!$%*(+)!%$+&)#+#$#")&&**%+'%"#!#(+"!+)&'"'$%&)$()+'!"%)(*(($+!*(+!+''('*&($)"**)#)((#!+%++%$+)))$*"#!$("!&''(%''$)#(&!+$++'(+"&!%!!%$!''+*"!)!"#'!#+%'&"$!#!)&)!&(*)!*"$%$+)""&(+$(%*'+!!$#$""')%++"+&$"+&($+$*&!)#'#*&(&(#!#++''*$"!%%#+$)!&''#!(&'+%'!%'""*$%&))+$)$(!%($+&(&'()"')'&""())(&("'+!)+&"'+#))***$""$)%%$))#$#!+'))'()&&+)"")%#&"!"#**#++!#$+#*!((*'"*%&)+'#%%$&''#)"*#+)%*!"'$&%#&&'#))#&!)($#&'+#('+#"$'"+'"%(*)$)#++"(**(
@r1194
TATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCANGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTAATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGNTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTNTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGAAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTNTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGANAAATTCCCGGACCCTTTTTGC
+
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
@r1195
GCTGCCAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGT
+
312CEB(9"*G!+++>:6-F3E85DE=8A:.*H2*@9@7-;3F.A@G)"+"@:6
@r1196
GCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCNCGGGAATGATCCAGATTTGGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTNCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGG
+
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
@r1197
CGGACTGCGATAATAATTGGTGGTNTNCAGAATTTGTCACTTCANGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATAT
+
1@.E)':+B'*36*",F<%B*%2!H+0G!8E32485?)B'6((!)8D2B"#8.%!6&D%B,%7<>=*3D2;&49?EG5=1#HB<6'78!4020&BAE-7
@r1198
ATAATGCAGCCTCCCCCCGNCTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTACATTAATGAGCA
+
(-D234#B8!&9=.$09:827G0?&8&.G3A19@81732-<GF75./8C;A6C(5G8#!!.57>=AA#3#/A'";<.F>!-,.8%@6-.F%4-69--;#+=<A3!:.#(=6:/,1@0;
@r1199
GATGCCATCAGNGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACNTATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTC
+
51H659:H%*3&1""@'(:/7839$%>4D00=,G?!A.!+:H58#??7!"-4=;D53*"-C=693)%79@7A3(?)&(B2/,',H4G=3>!B#(:3B)7$<AA6!8:@2::7F:E!#$:.0/*)!;+"'"+C7"BE1)/:,+9%(-E(+HFB&E4%>"/$1GDD2&@5A?
@r1200
ANTNNATNAAAATCACCGCAATTTATTTGGCGNCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGNTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTNGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCAAACAAAGCTTTGCACTGGATTGCGAGGCTTTGNGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATGACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATNTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAATAAAGCATTGCTTACCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATATAATCATTATTTGATTTCAATTTTGTNCCACTCCCTGGCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCNAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTNCGCAACTCGTNAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCNGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCAACTACGATATCAGACCACTNCATTTCGCATAAATCACCNACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTC
+
$%%"$"*#)+)$")%"#"&'*&&'%(&!$(&(++$")"%+)'"+#'**%))'($)$)$&*)$")#"*($($*%%&!$!"+!%)$%(!#&(*$#$*)&%$+('&!$'"$#$!&*"$#%""$*)$$$&()*$+'%)'"&)('%"('$!'"+*(()(!"#''$%)$!)*)+%!#)!!!#%)&*#'$+&#*&+&")!#+(*'')*%(%'&#+!%&"(#&%&!!)'#*$+#(!"(#($!!+'+&$"'*'$$%%#')%+%*#+&#!$"#")$+&("(&#*#*+&$''$#"&&*#&&'&$'!(*+!$)%"$*)&'+&##)&')#%"$#+(##)!#!(+*!!*)("(#!%%$#!(#!"'"%!%")!+$%(!''(%)%$%($%($(&+'#+%+"!)&"+&)!%"')')$+)#'"($)(#+'&')($)'"#+$&!(#%*(#"')'('(*$+''+&!!))$)'*$$(&%+(%#%&'+*#"+$'&(*)&(&$"&+(!!&!!$&#&&&)&!#"+")("(++*$"+$&*$*)$)#('*''")*&+"#"'")"*&%!)&%((&(*%+&()$&*$$$&&&!#'*"!#*)*#""+)($!*+('!'+*$#+$'"!)"+#"#(%$$*%!!#++#*)*+("$'&!'"#!+%##)!&"'$(!'!#)#'!""&%(!*$)'!'#"(&)#*+)&(*))#)**"!*&()&#"))"#&+')*"+*"+(**&$(((%%(#'*'(*()%+($&#!#'*!+%#**)+("!#&&))($%")&*'*'&+&%'(*%%***&#&'++$&"*("'+(+##('#(")*+++$&%#$")!'%++(+#*'#!$*"##$)*##(#"$%(%(&%)&)$(+*&'&($$$+(!**$*"*)$+!*&++!'('""!$*(&(#!"+$)##'!*)&)+("$+&&+&(%'&%'(*#(#''+!'$)#(!%"#!'#!%("!!+()$#&&%"++)$)!$!*&+)(%)*$''""$&#)'##&!*&'*($%**$**$&$"!"+&$'*"+("!$*)"(%$"$&$"%&#&("%#%"'&!&*(#&#(#"+)#+(*&#&!!#"%*'*#&+)()*'("))%))%%&*)')%*"#%$*+*"$%))$$'&&&+("))%#'+"#)*+*'&*&+$$#)"*#)$+)$+#%)""#+#*!($&%!!!(&!$#)+*''!&)&)(&('#&"'+%()$%!%""+%$#$*+&+$###&%#"%)&)"*#%)#&"&&%$)%+*#$"$&"$)(+'!'$"!+%+"')*"##'!'+$($'#!(&#$'()""#'$!(&!%'*%$&++%##))**%*!)&%#*('*#%"$*(!'%*)))'#"%%&'!$$+**%*)%%#)&!+!($"&$)&#!'+*+"")#!%'"$$!'()%%*&)$#
@r1201
TCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTGAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAANTCAAAGAAGCGGGCGGAACGGACAGAGAGATTGATGTATGAGCAGAGTCACCGCGATNATCTCCGCTCTGGTTATCTGCATCANCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAANCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAACTGAAAATG
+
9DG+G&<0?/?74E2A<8EF+GA<=!A2@B+?8.D7<+3?>)//!&(+7G*7?,69#>.FEC(C1)1+C9<&#E*CA$:3:E$*)>>+241.7!%D,"E)4EBFFH*=FD.GB)1G5>>B0'9.6-$%*3,7C+&"("9EE502<:G3:0765@B2;"9.%-=&9#,A&<*BDE4?;?0%-,!E7,#<%B:2D-(7D!**A(0?,02'F3?,";!-AA<+)(;?5,,.D3H2?@6??,.*F,;&E'!58108?90(D'&,.;*?-=7H0C1A/B)#.=D(&28&$-2C008,-6"<-G()$<-#G<%5;)@89E'>-3;::G,(((06-@@!9H!'=224D%-.1%!;:>9,=*%F>EB(/H(H5:-(E52(GDA(>AF*:?1(;#<&1'!+*<$;;$">5;(<6<"A*<$&=AFH3?%:DCH8G)56AE6B49$7"/AD)?C+3*2:&68
@r1202
GGCCCCCACCATCGGCAGGGTGATCGCACCGGNAAGCCCCCTGAACATGGGGATCANCCCGCCGAAGGAGTCCTTCTCCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTNTGCCCGCCTGCAAGCTGCATGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTG
+
D84"2H*71B-D&1>B:)G7?*/-"D0H0"F2$'"1HGF&&8H.8?;D4-!,-8'..?!3:-:/'$46$14EE9&D;HC2)(81<>,A+'0)%=3%)F$B;E@.;."+A9*/F$GA43*+C0D$C><H1D2:H(=??>")740D+)FC2:("*#615$$G9**H(B9+@7BH8F;H5."5A?)024
@r1203
GGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGNATGGCCANACCTTCCCGAATCATCATGGTAAACGTGCGTTTTTGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCANCAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCAATGTCATGCCNTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTGTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGNTAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGC
+
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
@r1204
GAAACGACTTTTTTAAAGGACGGTTATCACATTCAAATTTTTCATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGNAAGCATATACTCCAATAAACCAATATACNATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAANCCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCANT
+
)603%6'#(C+*+@8(4>EA2A@()*&H.?,F""E@AC'>E3"1C7G?@G:<"8(<*E6.H=3C2:%C$2;@!55,3E7%-$&A-(*:6$:9.$<F?B&*D%<$'H4-9A;1%*3:,(&@8.?()C.,!AH7C3"&+&/7F)!:)A'-A8%E$,':#*H.2C?GA%<97E"%"0C<H0$D6#'*&0F:/2.7@A.!0>,@9>!75G/04('<3H<C'7<<8@+2:;"@62C'53="F5#)HA?63'+D;H-#*.G+46*%-?;""EG5*FE5:9#F*-=-9!4!9=@C!>'("'"'E161<,*924%/+7@EB#2>246*D"@-%G54G"*@84&1%H@1'*%9$;-D/B+'@):E-GGC1A@<51&>1$8('G.HC:??-?78)>@E+/#G,;%B!G"2-+!)E$"-$(*#:41,)@F$B43!;(BE).G"=%)D0,<84,0,&40GG'2C8;<A"-CH92E&B.C2"1&)BE0=G8;=0C3-#H
@r1205
TGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTNCCGATACTCCCGACACTCCCCACNATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCNTATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTNTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCCGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTTTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCNGTGGCTTCCCGTTCTGCCTGCCGGTNAGTCAGCCCCCGGCTTTTCGCATCAATNGCGGCCCGTTTTGCCCGTTGCTGCTNTGCGAATTTATCCGCCTGCTGCGCCACCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCC
+
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
@r1206
CATATATGAATGAACGATGCAGANGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTA
+
=;/%8">5G<+G.+&<=A7H724;$D#51G8)E/*#E#H*)0+5C/6D-'9:C>$(C8'=@8:.
@r1207
GNGNCATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGAANCCATGGTGTCCGACTTATGCCCGANAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAATCTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATNCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCNTTTATCAAGTGTTTCCTGCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCTTCTACGNTATCAGACCA
+
("'""$(+)****'*(!&#''*"#!""!)%*!##!*")$"+*%"%)(*!$'"+)#"'((&)'#+)+'&$%)$##*$(*'+#%"*!!%")%$(#$+&!''%($($&+'&)!"!!%&$%"+%%&(($+%'(&(*&+)+'#&*%&%+!!(%+)'&$(((+'("!&)(!'($%#$'"%%)++"+)&&+*"+!#$+)!'*(+!*$!!%!%+"+#(%#+$)'%$%!)(&+%#!'!%&)(#*'#'$**$$%%#)&(!***")'$(!%*++!!%*)(!$!""'!##&(&!+%$(!("'&***%'#++'%!!)(*+"+%!(+!#!'###$)(!!)%(***%*()'++$")""+*#$')#(!"&&#%($*$&(("&)**%"+#!$((#*$'#%)!((!%#'$&%%!+"$#'$"()##(+%'!+#%$($#!&)+&&+%*"*!(+'!!!)(**+$+++%"&+%!'#"!()#)"*+*"%&&+'!!!!#&!##&'!$'*%)%"+'%!)+!*($)*(++*'#*($'&)'#+&!
@r1208
GGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTNATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCNTCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGNGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCTGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTANGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAA
+
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
@r1209
GCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGNTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGAGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACCTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCNTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTC
+
)=-;")H*5$:H>+2;'1-6AHH;!6'@7*1>9H==5>0AH'CG$./$B0G2<%)')&>@=E:?,-@DF4::B/1F!'1F3)3G'<@"F!27$;!H-.B:5=&3'2D:$$<;!%8*D+5@:?3?46;8(G,$>>9;1A++((H@53E6"/#<E!8108(H:/(:?A:H6'@4>:/E%$!69GA@G8<:/A=6"138FA5/D8+C0@B3E=+D(->$?!=:BD2@>="1:76,F0@C#/E7AC*#)-.:@33,>2+6>ED3)&;">-A;%.,3$:3/7.DE&C!C2%?9(98//?4C+;C/-@0/'H$*AA:F*2E,3#/#4<$459:?/85#8=%B#D?D
@r1210
ATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATNGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTG
+
1B1*;7G8F.=$>D!:('0A@*6<::=?A2@'5!>*$:0?.255=6.1)5<F#-C+8C?AB+;5;#<@+8F7@+</=!,<?5'>H:*F99>*-'@FD)3538=!#G'G3G@#(,?:<.)8#
@r1211
CAGCCGTAAGCTGGTTGCGTGGGATNGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGNTCTGGNCGGAGGCTGCCAGCGACGAGACGAAAAAACGGANCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCNCTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTATGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTATACANGNCGCTGTACGTTTCNCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACG
+
:E:FG9,2F91;4"-,6@*?E>+'"+#7EH0C.8;;#..'3H041H!8B:214BA/("B,>+2=$)7&7;80H%(**5G:)>A"*/4@E:#73;-.6%:(A0"A0>C'$(D*'H,D>'6189*1.C9.F<5363A%35H2<')/:<-+4EG?1FAA%*-50,1%6.0=4*@<=$17;@?E"427?<A:.!?A:H2B@?A6!,E-"8!;D0#(?333#/&64034@D#.4=4</9H#?#H4.#A?>;5)7C&/%'3A<7120!-*+!::B.<:E61)(?>?/GACH-?!0GH/"E/E&":/9,1<1C/%#()"9@,9)"*<&1)8-09D8F*@H0,(",;#+@C6#8D22=:6*!'&G44693>:,/DH56?HGH'9019HA6G8@)//*(2$E;.5";)5><6=59+7%/#8+A!7)C@"A5+8E5GF*"*6!6E:4,H224C=1#/H006G9(./F19(:E#5?8::03.91-5-@B1,G-
@r1212
NCNGAGTCNAACGNNCANCANGTATCGNNNCNTNGNNGCNANNCNNCCGNANNNNAACCCNNANNAGNNAANGATNCNNNANNAGNCTNANG
+
"$$!!#!"""$#"""!$!#"##$!#$#$!!""#"$"!"!"$$!$""$$!"!!""!"#!#"$$#"$###""$$#$$!#$!$$!!!##!!""!$
@r1213
ATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTACTTCCAGGCATTCAACGTTGTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTCATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGNGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAG
+
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
@r1214
ATNNNNNGAGNCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTNAGATAACAATTGATTGAATGTATGC
+
'%'("!"#)'"#($$(+#&+"'*&'&%'%(%%"+!$!'#(*!'%)(!)"#'!%*%*#%%&'%)%+)#!!&(&#($*%*'
@r1215
CTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTNACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGC
+
9BFCFE,90>"H+-C8?F?&;+>8!A@*<>H9.53?<.':H$F)%3;.H8!9),+B)>4@>"/#8599$'@+B%1A%(+H9#=9612>G(D"+*E?4/?A*D!'.#8(>.=#4=0*/<>3?'*'#C!!#'<:=!!E08.2@%2(H,)?'AF=*%+&A.><D2(E$A0<3B46(A&<.9C/.+5%1.B<D*))//'9!/E#,78?)$9H9@H')5H#!/GH0)(E;/;A(9B6<.>0%(--$#@A&H(:A7+A$&4C/#"7CA"-B99>$@<,H(#*6(9@")#)A,:>A9'&/H:==G@.6E/AA:8"&0,<H7@=>91/#0A)%64D"F,5F,"@H$AH@>E,0,H"AC6,=H'1=,#&.1*$AD')FFE,A?@&)':-3$(E+<+>0.*454F8.H7#?H+BG,:1+D%E*CEB*);19/9#3<G1$(52%$$+8B+HH+68>@)6C?-8$H
@r1216
ACCAATCATTCCATTCAAAATTGTTGTTTTACCANACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAAACACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCCGACAATTCTGGCAAA
+
#A@"FE#9H..=;"E3,:#F<H4#<G(H20?3FHF+0C%%6H9,2;C).F)75AH@DA#D,/D05'56&EC/:63@$C.*+#,"3=C1/C025;1"2=1H'"(G#<);/EA!B=/+G9+#/",//EE!83)!C6E#(4;-9@!-H3-A'=6$1!"8A931"+G0H>%=H(<:123
@r1217
TCCGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTANATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGNTTACGTCCGTCCCGTTCACGCATCAGGCGGATATCGTTAGCCCACCCA
+
)%!BB5.,B-#FB%8@8+0+"G('GH(H/'8(+A9(+G5%FC.A>=+%180C:10H')A.H-#170+(E@?6A>4((+-,;H>&>$74G2(9G.5";%3E&5,>H-43@8930B;**:A:16=-9*#5:@?@C!3D-,>#<6A6D7DD4/%<?)7F1F-A7D-1%21FE<H@H=$B>H4+)+%!"$<D+H#B=-=0=BCA)7>;32**6:$*$?5<4).*%E#4A*$,*F3+#GD9@88300:E1.2H;A+:1=-HF='@/=D-DC<9F?95H!/7>;+<4(0@"C8%=
@r1218
TCCTAATTAAATAGAGCAAATCNCCTTATTGGGGGTAAGACATGAAGATGCNNGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCG
+
E#C*=&#@B")(%)0!(;B%>,9!/#3$)H,=0AF$0$%A=-#D/2:99<67"),@(0@<:/B'-9AD32.F3+$)F3":1?C7<DB"-=AB:H4C(3/.#+%D?
@r1219
TCCCCATAATGCGGCTGNTTTCTGGCGCAACCGCTGCGGTGATCTGCGCGTNCACGTCCGGCTGTGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCNCGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGNTTGAGTNTCTTT
+
1B&*C)*/=*E+?E(GF$4"65CC)!H#"$@EH6@FC*4%88$7%+737?>H+,"18:$8"#@3!)9?@A.+-/-9,+$H9,!"*3%(4:*(D3*+<"1FBB,E!;>=?'0?$;-!?:32-H9*679%E;:D7B@/0%28$$1-1D!.&B%!,A*93H8#
@r1220
AGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGA
+
<6"5CF&8D6)A$E84>:9=H9.$.<571-G&F*6+#-5)HE#%84=89G+A;*5+'+4=-;&
@r1221
CCANGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTNTGAATTGTTTTATTCTGAACTAAAACGTCACAACGNCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTCATAAAAGGACTTAAAAANGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCNTGANCATAAAAGATANTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATA
+
*"'#'+&)!'+"%*)%+%*($$*!+'*)&()#$#!"+("()&)*$!$+)$)**++!+)'%(+%)#&)''("'&)&&&*$%#'&$&#*#"!'!+!##(#)&$'+#$""$*&%'(!#+$&#"!+*$$&+'$())&*"&!*(%*%$*'$!&#$"#(!)*!!++$**')#()&$$#$('+$))(!!'""))+)&'"+$##)("&%'%!%%%+'$$&!%&(!""&()*$)#&!*)%*'$#''%"*%'#+%('#+%+'#+!!!"$&'%+"*###)+$"+&%+++)%'++($$('"*!*$"$+&($+#)%"+)$!#*&+*#)(#'&)"#"$)#(!(($"+#&*++*!!*'&&%"!$$()#!$#&*)#'&%*)'$+!%!&&(#($#&+")%(#+*+('!)"&'*'(*!)((!)(("!!**&&%*&)%$&!"(%(''+!&*"%$!%!!$*'%*)')%)*%*"$$!%#&!
@r1222
GTGCCGTCNTCGTTCTCACGGATACTCACGCAGCGGAACAGTCG
+
A,?GB40)(94&!<D"78#H)(0+-7:BEF3'=339""<>16G+
@r1223
TTCTGAAGAAGCGTTNCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACAATCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGNTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGNCAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACA
+
8)C,%,(HH4+#?C/#-EGF2-%F4*>)G"%%E5E>*,;D,*(-HB*F>!114&*:'G(H6)78%;8,E!?F!%494@D)GFG6G4<B=B2AE-!5:@(?%)E#2<@01DA297212"-,E7*45D.57?+D3$D6%?64'+!(:E)=,"C0%"&&:#/2+9=5:;%41*&593=@A4)B0@>-$")'!3AF39#:<78>"@(3C=ADD7G+>#03:+C=0G';D#,*CB-,?,3$%4%(5-:E+4:%%&&H2H51*E3'?2-H$-?8-3),A*+89ED/B&53<20CAC':<3.C()EHHB$7A#;@H($E/?96B05777=G,-G@F+(><+1"3'?1%-277
@r1224
AGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCAAGGCCAGATANTGCGAGGTGGTTTTGCCCTTAATGGTGATGTNTTTTTCCGTCACCCAGCCACCGTTACGTT
+
&&E0$>(?H7().5G:F'2?HB'/A%8C>@3.=G63?C@<-F$H-A;.%+5+>'($<'&/G>F!&9D(,?<//.'@05:$,9?6,*H,78+-@DE./+0<+%:&?$A'2CF++!/+01$3%<'@C+??("?.B>#.9;AE<D=-04BB;>!5H0G6.46$E7E=D&@.5%(8G9&%7H?*?B&,!'2$@F?01.:#E"59C4(8&813!D?'7-F-E%CC$;$&"!A6#2212FF,<#F!F;A5=;(39)@3G$?)G(0GH?D/
@r1225
ATGTACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTGACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTAGGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACAC
+
""$2@H(.02<H$46>)D2H?7"C*649<E:$=7'4@,0+GF6<1?;#@F8/G9&+)85-A'G>/5-E=8!$%4!E*".3;:<,C62%"=7;BCH>(&,($@>6CH+=!,)>!0?**D5H&-G!87)D$!<1.?:"66134?5(;:%#C5H-9"3*775,:6B>-!3!3:1-!9@'?A"C'.;3(<$")"//4>-)"#4%!6!.GFHHC36>-0&=9.)G#"!70>FE8DHE?<HB@8<"*A4?C>/)6('/+$=)A:/;,!)2F6/4C%7)D;GB>D#@!2(7>;?-3)#9B:''+0H203%85-D!<E$8+#@.A1?:FD$9!7?=C-%4
@r1226
GAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTNAGCAGATGCGTCGGAT
+
F$@08="!)AA1%49@;+76-8#&3+'/@1.7<1HH4@9$+$B2%@#F9EA0'5
@r1227
GCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAANGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATNGGCGCGGNCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACG
+
,E0-)>0><*A$FH7$;5?,;8DA"H#<,=A&.>B.%4G&1>4@<2C"):""2HHH6).%@+==B.B3F)H="<H9'G>+",5>9)-2+B!2=>?'+C,>D';.+#@@)+$,-0<<931<CF(3ABG3*$:<05=0DB:74#1@;F07!!>'/CE)E&EGAH@5F@.9=-%'!&%A":F=)94+7>43497/0,=0@>EBA(B9B-$A@'.*86.7=FG.:C0-@=,58)%,)'(B5#-8C#H88CC=*&#6,?!1C2",H5;C+!<2!,AHG,.F%0%=B)-5;=')+#D)$
@r1228
CAAGACTCTATGAGAAGCAGATAAGCTATAANTTTGCTCAACATCTTCNCGGGCATAAGTCGGACACCATGGCANCACAGTATCGTGATGACAGAGGCAGGNAGTGGGACAANATTGAAATCAAATAATGATTTTATTTTGACT
+
:3(*,$:>:+G-">H>3'#&H+=:@+/DFD8!C%D2%%!,C$H$3.4(7B"E0.3"4,$)F9'A#*9!;&B!/246+==H7'<4A!'+4#?)$?,G$FB>53@8@=:&%*.$-:*9!A1&'B"=C5?'.:/'!#;?/=<?40&B
@r1229
CCNAACGNTGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACCACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCNCTCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATNCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGC
+
2BCB#AE.E;)(=B?.$-G%.FB!507859=D2&*1?4=%F1#FFA(7$E<#AGGF?$12$*/62<%,49$H2G@$/A=,>%"9#;48)B$@+,.)'71D#-1)=G40C+%+H->>0/)9$-+).;1$*0!A$.0"99-*B."BE!!$B*/A+9!2*&%9/"&.:%9<<@81A$?G#+GH>02*9.G""&;-4D$=*3*&4.9=<E%E85@H=+1:E*#HH.#@@"=3:.("3)-@C:+>DD?'ED?+2C;$$F62).37&'=8$7*D&D8+>(&+G6C7%,0(HA*&(GD<712.96AF%$;<$,B
@r1230
AGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGNTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTNTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTANACCGAAGGTAAAGCGCNGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGNGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCACCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTT
+
)DH6'1(E+398@)6%*-%:3<1"(;2%!6@C'%F).B@="B<B$!/17A<!0"=A3>*%D'(;3A"H>8(5,"&-,H*$9<='%F-EG$76=&*%9>01$&()C=+C23.B(-:%C27<<.<D5:1G@)7C(E47+*=F1$#'HH&6G:8%)+<3$41D*&!%BG:>@#$*<B.93+!C&3C('B@;/84;"@$G-8D;?>.FA/:C0!/H(>&:D)/'41?6(+(G878E:B7??9';C9>@%$=F0AC+*C;3"4/*(H,/"7(?"!+2GD;;4B)?684@#E*9H,.48/71B0B>/C)>F+DB/#@"*&*7:AC7;;AG2?0E*+421*/3(5%063<&%&+,C!7G,)%9'//?4E-8((3F2>90(..;(93?42@@2A-.8-
@r1231
GCCTAGCATTCNTTGTCTGTTCAGNGGCATTATTCACCACAANCTCATACATACCAGACAGCCGNTACACCACGTTTTCAGCATNAGAAANTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGANGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTNAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGC
+
%%#&&*%(*%$"!+((*+"%"")$##%%%"!*+&'%'%"!#(+#('"%)*#!)!)*&!**'&+""%"%&*)&'%*'+&&!"$)(+"""(!%'!('"+''$'(!(+!$&(+"()"*("$*"%+!++%%!$)(((%)$(!%*!#)"!'(')'&*+&'$!%$+($$%)!(%)$("""%*+$%%#%#%#")'$!)"!#$&!*!('$(+*$")'')$"%)!(!&$&&&(!(#+&'%'"$+&"'+)%#'*)'&"##$(!'+%")&)#'"($"'"+*%%'"+$$'#*!$)*$$&)(+*($&')!$+#"'%%&*'#
@r1232
AACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTNGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACAGTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGNAATTTGTGCCACGCATCATNCCCCTGTTCGACAGCTCTCACATCGATCC
+
4*9/+/(3(CD>-*CD.)GG7BF");*0'F2C@$7055(G26;3%17D-68+82#@GBB35''A>?,/G*33(;?22.,0;4!)*/9F,<6C'!!(7G/9,%4>;!G%/21$*%,=33AB9+EG(6?A1=6*:'4)5E?,'/A86A2H)FG';%D"F6.('A7FF@?.#A/=9,!(/$/+1)@9!@>),D!=%";,C7;$('8CBB-';CH'E6'DEGD:/C<%*8#@@C?(.0C(0+,93B9&?)#:!91+%F<%;<5-35D5$'1)(6*!?8+8.-<G<*>#;3D2/#;5;$0G%A1*35EH049H<*!8GG7B%+*((;0194'D8H!#>"&$'7;>H@,<%2,.7=9/*3'G-"BAF5G#:,B9=EE$$")8$&6$(A)D.*'!8=A<D2
@r1233
NCCAGNGCTGTGNATCCTGTACATGCCGGATTTACCGCAANGANCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCANTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACG
+
)!*"$*"'!"&+#&)&"$$!%%$%+$("'#*($#!!*%*#+)*%$)*)$((*'+!&&!"$$(#'*(*!*&(%+#%*"(&&*(#$!*($*#$!%)#'+$'!!"'%)##(%"%"!+*%!!)("+%*%""'!%&&%)('&)*)"!+*%!"+*"*'$(
@r1234
NGCTTTTCCGGACACAGTTCCGGATNGTCAGCCCGAAGCGCATCAGCAACCCG
+
34H!1&-@'EH>?-AC.&<+A@$C>&&-==*FF+H55D-.D*(;7452%/A18
@r1235
CANCTTTNANATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTN
+
$!$('&($!!(*%*+#(#')#(+%#%'"+"%""%!%&(##&+')++"%*!+$!%$"++'%#(%*$!!*)&$*)+%)%
@r1236
TTTTGCATATTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGNTTTGATGTGCAACCGACGACGACCAGCGGCAGCATCATCAC
+
-;+8E%!5#*B4)7H@=!(HH#(<B.D7-A#9+#H9:D>7;(*=*0@10%"8--96=$=8,--F-)CH52>'.893!,D9+*HG+!:"B/-9E,5/B/.FF;$C=12)9"0"A#+,:HA8@?E3CA2+%.77)51:;,29:0C<+7FAAE?1?AB+3?<:!=D-A'8HB
@r1237
NAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATNTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCT
+
'6?B&=DC%)>+4<=A$>,2CD3EB+2'')2.E4/+F(.?F+#6?:(+'#H%7;CB0+;00C**!,A9?3G:E)/5H37G-,;;<2#C.8'AA3*=6-/3.(773F/*"!=<DH"8*99
@r1238
GGCATANNTGTANNAANAAACCCANCAGTGTNTTNATTCCAACGANNGAATACNCGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAANCTTCTTTTCNCTCCAGTGTGAGGGCGATTTTTTNTCTGTGAGGATATGAACAGATGTCAAACATTAAAAAATACATCATTGATTACGACTGGAAAGCAACAATAGAAATTGAAATCGNNCATGACGTAATGACAGAGGAAAAACTTCACCAGANTAATAATTTCTGGTTAGACTCTGAATACCCACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTNCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCGCCAATGGATGGTAGC
+
($(*%)##*"#"('#(#&$&&!(!")!$!''$"$"$()%&('%**'++(++&$(&)+('")%***'*&$%$)'#%&&&#%&(*(%!)%(&$$%!%)!(&#+'#%#$&!+))*$##+)'+)&*)*"&*+"(&'+&)!&!"$!"$)$)'%(!)(*)"'+"('+#%)#***%+#+"'%$+%+$"'$*(%'$"')$'&)++$'+(+#%'+('%#+'!&#""!$)%("$%$")))"%+()$(!(#'*&#+'#(%&'")"+#'"#!%&$($()'*("%((!$+$!$$%$(()%&$'+"&+"""#)&$$+*&+('+$(%'#"&&'+'#!%+(+*#'!+*+*&"%&!&+&)+"+(!"$%!!$+*$)**$*((#"))!"((*"!**!##+)%&#%(+$($$%+#)!'&")%%&%%*(+&+&&&*'**+*!*$$$+$#++%'("*%%*+%+%(&(&
@r1239
CNGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACNTGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCNCTACAGCCATCTTCCGGATGACGTCCGGGANACACTACAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCNGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTNCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCNCGCGTGCTGNCAGAAACACCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCNGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATNGAGTGCGAAAGCGCGTGCAATGACCCCGCTNATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACNAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAANTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTNTTTCTGCGTCTCTTTCTCCGTGAGAGCTANCNCTTCACCACGGAGAAAGTCTATCTCTCACAAAT
+
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
@r1240
CTTAATAGCACCATTTCTNTGAGTTACCCTGATGTTGTAANTGCATGTATAGAACATAAGGTGTCTNTNGAAGCATTCAGAGCAATNGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCNGGTGGTCGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGNAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTAGTAATTAAGTGAATTTNCAATATCGTCCTGTTCGGANGGAAGAACGCGGGATGTTCATTCTTCATCANTTTTAATTGATGT
+
282H56$CD5*A+(F/&8G2&//:":>5G-;G<,.<#(H,470?F775'%F66H!$C:DD<:GF1*:'2*A=!'7:?-BF#3E<<'C*25&EB(3%H;#/;>.5150(F)H=#G.%'3=$?6+?9&H..5<?)*@&DD$(+E8%3;A9,32<(B49?'(G+C)(44H<%/)(1#>../G!-)$&7(-*9&1&E@#%=H99&BH)7E4>-'9140@#8&(:655<=;-$18;#7;D0"50-(>ACG*5B-54!E<=E*</96$E$&;B,/33FE)&<1G=-9#<81$+DBE6"(69A@D?4.+)F)<="='@%',=HC%5<G:,'?@&1G65?/(%$4+
@r1241
ATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCAATTTCGTCCCTGGCAGTGGTCGTCTCTTNCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACNGACCTGCTTACTGATNTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCC
+
5+HBA*9@94D0B!HF.H*%*@F.?/H>/3FAFG0#B>?+D,*;@::/2&/1!46$1-F3(H:6,",5'E*G0C2*#??752#<CE.%HC112'E)!4;*!5H&1=B9(6*@'>7H";,2(4H<*=.!53BA!*+EB)B=.B$!<H6D)C<&.;)B%AC%9%=E-&G$1)0'A%)$07CA6?'$,9B-"%="(0>.$G$*$@;4)5,+&9(1'!7<2'7?<#=85,B<C#.?-87H35'FB,'/$-A2%9C(4%1.0!)B-*"8*&1-6A.<+$%64835"B(3"+5:';D5C%%-@D,=F>B97D06*:9%H%&*"6%
@r1242
TCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGT
+
4F%('@"B;6"9-/?<A4=##@B>&,A7)7$0$F:"<1)'<(@)(H
@r1243
NTTCGAAAGANTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTG
+
""(%(*$)%(&+()$&)+&($%%&$$!)+&!%%$'$+"#*'#*%"*
@r1244
CCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGCTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACNTTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACA
+
H?1"3*$C>!;/-/.HDEE,:-5@%C?*(9,G..53);4)B+@B=AA9>!0=DC-C5!<8"@(!9=""G@7+!4+D@!EGC/5A/E?:BH&)A#@A&-'0A3E)0#0,8)#9+H-;0@F47!*%)7?H;8>'.86@$AF+,1?,746A@!*%.=)$7"
@r1245
ATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGNCGTTAAC
+
<#!?4>%<%'(**1'<2?8:#<$<C<9@@0>(-$1#6+G/8<C''+3>>/9"EG<H
@r1246
GGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGA
+
,G2"6:<H*;-HA9+,C+-%6#1%C:*E=+:!C'F35)</
@r1247
CAGAGCAGAAGGTGGCATCATGACACCGGACATTATCCTGCAGCAAACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGTCACAAATTACGGCTCGGCGTAATCACCANTTCAGAAGTTCACAACGTGATNGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCNGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCNCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTNCCTCCCGGGATTTCATGAAGTTCGGGCTCGGTGGTNTCGAGGCCATAAAGTCAGCTTACATGGCCCAAGTGTAGTACAGCATGTGGGTGACGCGAAAAAATGCATGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCNGCATTATGTCGTGACTGGATGAAAAGTACATGGCGAGTTTTGACGAGATCNTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCNTCACGATAATATCCGGGTAGGCGCAATCAGTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAANGCTGGAAATGATGGTGGCGAANGCAGAAGCAGATGAGAGAANCCAGGTATGACAACCACGGAATGCATTNTTCTGGCAGCGNGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAANAGCCAGACNGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCNGATGGGATTCACACCGACTCATTTAAGCGTGGCAATNGGCATGTTAAACGGCGTCTTTAANGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCCCATNCACCCTCAAGCNTATTAACCAACAGTTCAGGGATTNATGAAAGATGGCAGACANCATTGATTCAG
+
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
@r1248
NACGGAAACCAGTTTCTTGTTGTTCGCCATCCAGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCNGGAAGAGTTTCTGCGGCAGTTAANCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGCAAATGCTGAANTTCGGGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATGAATTAGTATCNATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTNCAGNTCCGGTGTCTTGTCTCCATGCAGACATCAC
+
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
@r1249
GATNNAGNNGNNNANNTTCAGNCNGCNAGNNTCGCGNCGCNTNANTNNCCANGTNAACACCNGNGGNNNGATTNCCNNCCCTNTGCNNGAGCNNNNNNANNANAANGNTGCCNNNCAAGAGNNCGCNGNGNNNNTCCNCNNGGNAAANNATGTNNNGGTGTNNGNNNNGNNGNCNCNNNCTNTGNNACNNCTGTNCNCANATACNNCAANCGNANGCNNGNGANANTNGNTNNTGGNANGANNTGACACNCNTCANNNGACGNCGNANGNGNGTTANNTGCTANNNCTCNNCGAAACANTCGNNNATCNNTNCAGNTCGNNTNNANCTCNNANNNNNNNTANANNNTACACNTNCNNNCNCNANGANGNNCNGGGNTCTANANGTNNNCANNATNNANNNNAANNNNGNNCNNNNGNCNTNNCANCNTAGGCATCGAGNNGCGNCNNNANACCNGNANTANCATNGAGNANNNANTGNNAGCTGGNTANCNTACNGNTANNANCCANGCCGCATCTTNNCNNTGGTGNNGCNNCNGNACANNNTGAGTNNTGNNNTNNANNGCAGNNNNTGGCTGGNANANNANATTTNTNATNNANCNCNCNATNNCTNCNG
+
$#####$#####$$!!$"$!""""$#!#$!#"""$$$!#!!$$$"""#"$"!#!#$$#"$$$!$#""$"$!"#"!#$$$!!""#!"!$!#$$$$!"!""!!#!$$$$""!$###"!"#"##"!"#"$$$""!!#$""!$!$"#$"#$!"#$"$#"$#"!"#$$$"#!#$!#!!##$!"##!!"$"#!"#$!$"!"""!$!#!"#$$$!$"!$"!$#$#!!"!$!$$!##"#!!##$$"!"$#$##$"#$!#!"!$"!!#$!$!##"!!#!"$!$$!!""$$"#""!$$"#!$##!"#$"#!!!!!"!#$!$!#""!$!#!#"#!!!#""""$"$"!!"!#"#$##!!"$##$"#"#$#$""#!#$!#!"!""#$!#!!##"#!$#!""#$!$"#$""!#!#!#!!#"$$"#$!!"#!$""!!#"""""!"#"""$#""$"$!!""!"#!$##$!#!#$###"##$#$###$#"#$""#"!$"$$$$!!$"!$!$"#"$""$"#$"$$"$$#$#$$$$$""!##!#$#$$"$###""!$##$"#$$$$#####$"#!"!$!$""#$"!!$$!####!""!!"""!"$!#$$#$$!#!!$$$!#""#$!"$!!#!
@r1250
TAATGAATAAGTGCTTACTTCTTCTTTTTGACCTNCAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATAGCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGNAACACAGGATCTCTCTTTTAANTTACTCTCTATTACATCCGTTTTCCATCTAAAAATTAGTNGTATTGAACNTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCANTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGANATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCCTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATANGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGTGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTGTATCATGTTTCTGGTNCAGCTTTTTTATANTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGNGATNCCATGGTGTCC
+
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
@r1251
GTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAANATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCNGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGNCTGAATGGCTGTACCGCCTGACGTGATGCGCCGCCACCAACAGCCCCGCNAATGGCGCTGCC
+
@&@%</F2A!6)(*$,+=B)=>C6214.3F17C(F0)B74C59*'@@,E<2A?)3.%5%)#-&G6!>A>,(5"?-,H85#/7@5;5A$8:F,H!<:AG8)F<H-:->'6-@C)40E;=D;=!7>CE7A4D;/B(,G(&?05/#HE.D*/F($5+%B+E@9$56*60A;D$'58)?;E#&9&"D)*B/('>/!,!$*#;4),56+<:%2E;9B),FD+%,63=2C-.(;(32,7@A17*E="DH-
@r1252
TTTTACGTTAAGTTGATGCAGATCAATTNATACGATACCTGCGTCATAATTGATTATTTGACG
+
2A+)&D,",,,44)>&8&GG7B>!6F)F9B+%>7!G':8G,,8H2)#"!.@>(;C2466@#7-
@r1253
GACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACNAACTTCCTTCTCGNTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGA
+
FA1*F#&65>61%DB?<).(?8C<'3+33:7623%5*D<>G1,7520-%37-H$8+,"2A)3-'4*C?>1'8%919FH%H)FA(9#AH(*!$D*@9:;F(C&4$$>A7/=H&!"<&F>('+8
@r1254
NGGGGCGACCCNACTGGCGTGCCATGCTTGCCGGNATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCG
+
#H;'&F6=<?F<D6<H*D:4/D;:<-;&.>*7:*F;C/A=3;*8=96H:F>(C7ED*D6=(A&E@F5.H4?G;:.&)$HCC@9=/)GG%G9-9"-)/+G43)<,.!AGB>6*,--+(+'F0**$*<."%@:=134!BB+D%A-#:&)??EF3.40#2&"9'&!,<HD&3486:31!6F1$-4/$;)@)G#.1B%6;@)*F6!G:,*.D0==6D6*<)3/6%5CH!/=9*@".G#B422#0-?HE.(91=
@r1255
GCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAACCCCCGCCNGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCNGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATA
+
7%1<)!="+"31<0=?/&7:"90E8$=():,<="D61(%FG=2(6-8C?&DG"0<"G;2.?>,0#C"106-,'%0E6A'FGD2#15/>*F"-%F;$48##'B4+-..#A/:<2A2,A>,CGF@>DGB<;=+1B;*);H=?+(8:$('.G@;<BC.)-AH&"/C!:9%*1C!/,8:2AH"C@(@%C94&);.@3;5E+):&EH>)%E:$/4!4&@G?;4+F;)#(%)7?"&4=/ADB&(,<8'7'<(2<9@DH$.E,/>*F=@!A18419(#CFC(&463?'<*E"&4@"A(AH
@r1256
CGGATTGGCATCAGAGCTGATGAACCGAAGTGGCTAAAGCCAAAACCTGGAATCAGATATCTTGCTGAACTGTCAGACNT
+
#+$#&*#$!#'+#%%+&"(+!(%*!)("#(&$#"$'*+)+'*!'(()'$#&#!!+'*!+))$')&#"#&(%!&)%&!++!
@r1257
ATGCGCTTGCTCTTCATCTCGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGC
+
%"+%))++*$#'*&"*("%(!"')*+$&)%"("&)&+'$)'+++)&*()%!+")##("%')&#$!&)!"#*"%"#'&"+%+***#!&)!%(%!!"%)*"#'"&)#)+'!%!&
@r1258
CTGAATTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAANCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGCGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATG
+
-)=,D@++6>";F-(6A.46!#01H-(<67)1)>60.@@D1)00HE&'35+)H=/$-#($8D6/#.::(<'D))3*74F!!,;5;7>;C940<1,E'4G5=CBC0/=$#F:F998@,@+F8:*#,'230H5AC;0!;/!GE@6!$=#%8,6AF/0G5&+"$$6)!6C%<2'G83<-'+!71H=/?4?D4,$(/E**:BF>E%F3%#0F8-%A##;#?$!F6/?F>#A!3;26#$=9.3,*84B)>5<9:=(G6&2?%2=3/&ECD@6F&C40-A:&A-/F$.&:%9':G(:#@87.;C6+&50.-9#:@D,G/:6&$/B##E/2#8"=?.&?5'&?$1,770;18#D$:$D'0H2+H2BE">2.,6);C;0C')B+B+DHB)(A0(DG3?3$4G-(313E,1#3=&H7>,C/C<HB9.4F/<""
@r1259
TGATGGACNCAATCTGAGCCTCACCGCTTACCTCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTG
+
2E"F@>,$GG:*$:6EA3B%3"/?!;0)(=:D#<+%7D!='#)".:3!D8C*8(:'7=)0812'111(5/)8:9G(8E00C<H'90#1H:C)H1BC5F6,E$3?-=C(+DC65?,5AA.2,#)=+4=E($.F%%"%E?2D3;06=E,B#>D>#A1!B=?*&/*@7#D)&G?#58)-,2#A1,F=9.8!4B<BE3<*0,1&=<":<26..G.(2/?4>.B8@EG&0%@%+1=."8*/H24#G%+5*F+=##/@D4D>&B"-'G.
@r1260
GNGACNGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTNCGTCCGTCACGTTCACGCATCNGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGNGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTNTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCTCCCTTTTTTGAGGGATAGGAATCCCCCAATTTGAGGGATGTTTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATNTTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCANAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGC
+
)!)!"!'+)#!&!"$"+%*'(&%"!)#&%&)!))$!*#)!&!&+%"%)&+(&))#+*("&+#$+)'"("(++((**(%)*$&"(+*&%&($(*''('*%'%*+""#*+"#(&!(*++&(""(%"#)'&+**&!$#"++&#"!+"*"#+#&*%*&'%$$)"'(''(*!+%%&"(&#$$%#!)#*++!#$*&)&'""'%$%""#'"++$(+%"(&%&*+'"%%*+&"$+!"+#&!%(("''!!!$"!$)%#%$$#%*#&!()"!(('*&#'!"()(%#+*)&!&+%#&!!"')%'"#$("&+"()%&(+#(+&)&!$"$)*$"&&"*$+("*+#$*!))*(**%%)#"!%#+'"+$$!"'$%"!%)##'!'"%(($$%!*'#$!#+)"!%)+))$""'&++#+'!+#"$+$*)"&+%"$+"+()!#")"($#&#%'#"+"%(++''%"#%'"+##%)")$$#$!"&*#))"&'&+((!'#)*)#'"&)("%%)%!#+'(!(#++($((%#)*((%(+***!+'$'"&%%&*%!($&#!%!!('"$'#!'&(*!)'!!""+(+&&%%+#'&%(!)'&*"('(!&#'"%!*""+$#!+$'(*))''+)*+&(*!'$!*++"(('$*'*)&*##&(+()#$*!)+%#*%!$)#%+%&$!$&!"*!#(++%'!+!
@r1261
CCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCC
+
&C%?-B/&4"70CGD61D+A-9C+3*H=>++#B0E/->39.5-;038+H1;2'$$A<F+4HA,8>?9))<=;;!35'8<9D
@r1262
AGTACAGNGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGA
+
'<1AD8:52B#?0C-@7+E1C'322=3H(8*.7A!389.0*#*D:)1@313H04C7;-G/./E4F*G*H$7!2+B=#83>"%#,AH09B(%&3!5(--?8/.)5=G<;<-;2FH@BD45=253/17C6H/3H!B5,=5#)E3B.3?4D@=3:*E@0.($0@/"/DEA)B0B&H8H%C=#,+B2"-/8?59<85=HEC
@r1263
GGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCNAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCA
+
C&"2+8&,#%77H6C+(58DHB.E7(5A70&3-16$H*/2>H6$;=4D/+=&5*+1*/4;;"6(H7)"91?D(G/.)G8-;#682?,B%/F7/'EH%*1:D%EF'=.G?G;#?@5=/F2$&F#*@&#+820*%+!2/A0/*/>*7<-D84#62@B)+9'<B';"<$'&!%6B*1DB';9(@@<+8A!<G8*!&H/:"0D*>4:B4#A944'(*3>.-#9'(E=C0:$4,@%*1?;-&76,4B<"!!9D/$.?>E2:%B!-!B8A!@8".=DF!(*39C>2@
@r1264
NANNGTTGNCCNCNNANANACTNGANNANGNNTGCNNNNNCAANNNNNTGANCNGNTNNNNTANANTNNNNANCNCNNNCGCNNNNNNATNTTNNNATTANACTCGNTNNTNTANTANNTCNNNTTNNNCTGGTNCNNGCNCNNTNNGCNNTTNCCCNACTGNTNNNNCAANAANGNCNNNNTCNNGGTGGAN
+
!$!!$#!""""!!#!#!#####"#"$#!""$!$!##""$$$$""!$#""$$!$!!!$!"$$##!#"!#"$!!!#"$#!"#!!!$""$$!""#$!##$$"$##$!###$###$$!$""!"$$!$$$"!$#!$#"$!!$"$!$!"#"!"$$#!"#$#!$#"$$"!#!$!##"$"##!!!#"!!##$#"$#"###!
@r1265
TCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTG
+
C?$G>9A&+"(-)%2/CD3D4@#6)B04BA;&H$><+H(64*9.>,70&7
@r1266
CNTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCNACCTGGGATACCAGTTCGTC
+
*$0B89=49G@04*:D6"D""&/4=.H090A!.:A3E4EC?D$,2=E0FA%34A)*")8DD<:%0.!)$EF/*B/@:<7:>@4#:79E-*=@#GF<B@*$>'.5C
@r1267
AACCNCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATNGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGANCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAA
+
>(5#<H;9-E+.,@C6F$F)D=9.4B0%.>'H"123*$7<9794.552:?E(3E"+"+$>8..E+&6<(48!<-7);!A302')+$F(='D-D$&#C"@,6.><$":F0;"7(;-";;7@'=<5/6=!A#4G'+03H23#H!,3*#+@=2DED&:?G;6/8-25+4+!A"4(27-9..%8<E*)$5@?.)G"H*"1"'AH@9C8@$B1?,1;.#6-?F)23"22';1/>-63*841!8B9037$3&<+3*0!<=A6"%99@@2/3>*"*3(&+<;(F501.C!+.2<$,EB,E!2(7G-&'03"864*
@r1268
GTTCGAACAGCATCCTCAGGATNTGATCGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGA
+
B3?54@98/;8D*('&<BH;;E!F1$/?-=-<8D?F>D9-6!H1<&/D%80'7#5&*4!/!#6)?03-D.)92;2+F)0H;&D%"GC8$:06:1-H8"7/:**#4:;.(#;D762"#5%70((*1$2'A(&+4':B(#HD2(F<G
@r1269
ACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCANCACCCGATANTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTA
+
*.<'2"H$;2=F**!4D59"HA;8":(/D2&3;H+5@227:>941'8/&3D)3.(9:'@/5+3+7F,%<*F-:(.B80H':G**D.5,!1@+:<2*-5",;G>0H?'6&H@71@"22H5FA*%A,;5(.=7-E*.C,)6@AAD744&8B78H*,+(;-#8*HC:%<.<%<G,?";?,7!-D7$E8%30A$18@22?BH@':&.*F*A>##2F!#HG!9(.34A>H(&G3'HB4%!;48A7GE&@3E:@>=A64))@"587>';%7)",39!:!C;F6"D=9+>#8.D#4)FH@:A(+"/2>)".3+/2171>
@r1270
TGCTGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCGAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCATGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGC
+
>)8&3'6"D#@F./*"/5G,EFC.9D#E$<.?B:"DE9F74:8&H-GC:8@6>.&4)7+G9.F$3)8948F5G>?;(,21-=BC"H6H+7#0(877./:7*2>70:#E/;0'/)G&"+4AA>4</>D!2&#'F*H+517@B0(7E9=C?G%:7C5'G%.49?C;>!7:H6#%+:ED3A=;C5&>CAA0><&"2G(0$&E<,ED'*9(B='9F4A!(9@(/$G&"-/8HC?A*C0*>78,@@6?1!(+29B:3D3-D>#G.A)>682(:8#%GG27D$<E06/6>;<1,A:5.1A+875D;2-6&C*%C8H,35D!/=+HF$112;,1>467C$G2+')!13'<6/F:,8$:@0A7
@r1271
GTGAACAGGTGGTGAACTGATGNAGGATATCCGGCAGGAANCACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCNCTGGGAAATCGACCTGACAGAGGTCGGTAGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAA
+
!/*G,?:.*3'2F,)5B$;;A**/4:,,%@9&G?=,G1!71/)3$E'<<+9"%"?7E=31?'D2@:0./02+$%7GD%!";98EC*."&*>8)@:3*8#;">D3/"9H*-39.("C:%CAH0.?>$8%GCEB9@(G292.8$F95&3/53":!C6;E/>):E($6'<<0C4D*$C-B?(F*('&,!65-%,*2947/AE1G1G7D+<6D*)@6C"/E-C97%)64BCD622
@r1272
TATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGNTATTCGTCAGCCGTAAGTCTTGATCTCCTTA
+
%8(#(.A<1!B/:%"/?@&#000F*<F70D'HE18A&5/&H=6"5$*&%0*E.2&$7.HH&!+E<(371)E5,@/<$5)D96G6A#4E2AF#.E+E3E%.1*1@+,9?>E5*B$B>&0$,9>0#B>=:7B:#=7!7H/:C9%6=70BB-188AD+$/(6=5G+?'/B8H4&9)$D%&'E!3@#$*0:#:1+1B02+=46A:HCA2"E1=B2)1H,<0;%%?;4%)=5+*5H0E13,&3#"2A1=;42?4.9#@=?4&0G9('<>,)9H*89%'&@%%5>$+C=)>1
@r1273
ATAGCTGTGAGAATATCGCCCGCGAAATGCNGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAANTTAGTCTGGATAGCCNTAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATNAAGTATGTCGATAAGGCGTTTGCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGNAATGGCATATTGCATGGT
+
=+-D/;/-.:*8E;@!EH0D)!.$;;4G?)9)4(.2736C@EB'258@3!@.-"5+@$,4)F<=0@.';@G'3$6%&:@59#2,&C#57.1E">C1;42@1H+4CB'072/E/:/+96H?0G>7)07/4#0@?(1>"?)<4+:-;=G2+2+<'?>A;1<1(%+;'=/:"H.>D7G-=?)?+>-8-21$G71$B,.?H.6>;-G/1-5=<E(%.G8*1@=$>">9,@.,=91"E&=:D1&@754B6B(=?*"+"3F@:@$G0F91#$E,C+'"'!D'3!A+>G"<48<)+.5AD<4;'8"7-$+G+0HD40?DD47E7'#1$EB8.'G-$?&B7<02)<%
@r1274
CGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGNAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGNTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCNGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGC
+
,D,:+G0=@23;=G"%&,:5G('7";/D+?9:6E@4:#,,"/::@9HC(H!(@"(%=E>;@-(0$#GB0??G3H4G.-1:G"G,""!/,.$4D+"A".=@;<<2;?,DGHH@!&<97?;2E0;*C6)0)G"(51A,-7):A#7+059,'!:-,H"35>H:.!":CHA>+0E38B9;5.4H857A11?+:?<>(:.*E#+>?-.:B4E/E'A3F2F>F1!<4&"84?/D4B770B%%6".2*F4D4F$F4@!@,D>6>;!A?.?+1(<3CF9>')*-"1+8/9A/CE/DC@.*D?5H9%,%67,;?>"%6C)11@D&)?9(@30/*'>':;;&$3;%93&.-$7#("AE,+!FD$
@r1275
NTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTNTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATT
+
#*.D5(<<693".77,?5*4>/74$BBD<;0"CF/%A27>H4E*E(D8H,,79>9B5:%HH'.D>%%"';3>6.E9.HF+)*E0G0**=61F?5.4:40E>/H<"$+'+EA8E3E>H5<>799HBGEDH->!'A;?:.)+@H#10H6.+<<'27H7+0H7('D)@$/;%$?#299A*
@r1276
GTTCTCATGGTTCNTCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGC
+
C?A2(6"'>1*;?.EH2>)?>#8!6D-*054.(-#"GFDF2#*%A-$FD#=;3-'*/,&<@%=5
@r1277
NATTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCNGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAANGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACATGTCATGTTTTTCTGGCATCTGCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGG
+
"(++(!"$''#'$$!+)%)#&$(#(%%'"%()%+$)(!)#(&$++&+)'#)&&+)(#&+!%**+"*#%$++!$'&&'+*+*")$%)#%%&)+"%#)"""&#()$#"%)*)+"%'&&!%*!$+#)!(!+%")!"%#"*$!$$!*$&*$)##*#&*"%(&!(&*+&'"$+&$()%'""*!!"""'%&"&*#"()"#&*"'(+$'$'&!%+#$(("%%$%)+%!#+#"()#'*"!(%'&*#*#%+"')#'(#*"%#%**%"+*(+&&(#'"!'##&$!#*""#$%)%#"&(&)&%%"%$$&)$&!%*&+("!&#&"'&(+&"#(#''$'!&#%#"
@r1278
GGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAAGTGCTGGGGCAGGCCTTTTTCCATGTCGNCTNCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTT
+
462)A2+!+;CA8&(@,/HF?8:&()H!G8<:8@F%"<D=E,#)9C=749@55D?6'?20FB.*B!3E+49;.:GHD49@F52C<F+5E)A)9:.$2F68'*!(/5!5@E7F4$<FE--'?G%4!2%%G4<&)11""D.2C<BH$F-.3F"!:H)+CE+'+G'09,:AC/"%66.&1FC=D,-$-0C9GF&7?6F-A:F=%9,#7*.B+0#))&+5B77A2#;6,'@;3C&-3@#4"5%#;C:&)8!05(>H#4/C7==G)B+44AA4
@r1279
GGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAANTTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCC
+
;=4F".@96>%&:H-:5#$:+?)E?)1(<&7@90HH1H*02*-&<9,"(;.(/7"H;%-4E'/<3>8+(76F.'*%8+7#1&,:@E=6!)83@&C4.)#,D,>B+<)6:6E1,8/F2A">4,G0-1/E-%<4B1H>:3E-5E)147!9!5D+((A+%"84=4+1''29:3-91
@r1280
CATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGNAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTNNCGTTGATTTTTTAATGCANAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTNCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGTTTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCNCGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGNAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCNGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACNTGTATCCATGAAAACGNAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTNCCCATCTCGCTTTCC
+
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
@r1281
AAACCATAATTGCATCNACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGC
+
C)1/%D&=1#A-)?E1-,&&G5-,)8+<%FH5)$4+A&+'FB5FDD19.9,H'(3%-B(5!:03'&$D#B#A!,6'&6:F7D1$28(<'==@($<(&9727$*7D**DC3@%4AC>-C<AH@2<33(*$/,A.B
@r1282
ACGTTTCCCCATGCCGTAGCGAGGATGGGTCAGCATATCCCAGAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACACCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGG
+
$-6<?B57>C'>:(0$&62,-01$9928B6;6>#.HG6+<8=))<E+B=&!;A"'#FF(?C$.,/<G9=@B!5-'+"?F7(B$A4%FD$D4C8C"-:+8=GC?%1F/@@H)-H$8;"'G:2+>48796(8GB27E.B%9"6,(E,B$B4)D+H'D2%5-4;6@<+G2D;/!5(!-".#AD14.0H77<$H7G.<*-?.)/H*=6H,!)#D=<9H1#,G?(668%C8H='5-C<*+E1%4-0E.?2./)-;!&C:8F:.$*G0%>%G(.-*-!,8#AA6"F7%/!G4?,FF/B.E-C<4&C=+H<!HAHEA=<*!@$GA;/(@D&2%5:07G!E,./,D(0.58.#*+C=$6
@r1283
NANNTGGTTTCTCNCATCTGATTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATT
+
#$%#&+)&#&%*%+$'(+(#)%''$%$!#(!$&""(%+!#)!"$&)%#$%#&%($(#*!+#%&)&&!("%&)'('(%*!'!$+
@r1284
CCTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGT
+
#$D<61EH=3+93E;F?"C!,=)FB-%F4&665!)&+.(E'+!
@r1285
CAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGNACGTAGCCAGACNGAACGATATCTGATGGCCACGGTATCGGCGCACCTGCCGGAAANGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATNTCCCTGCCAACCTGAGTCAGTTCAGTCGGGCTGGCGGGATCA
+
AG(+(/A,#F=C+)72)F"<=HFE)H0->350!&G=BHE":6?C7#H!AF9E*GH+?;59!2?G1$,!//?43A%"!BC:5;H5?;7F;G-B+*5E?7-7CD!C9%)5;;G&GD?9)1:58E+F+36!2"=D0C%8'5:5=/!B9:GH&E$G"'?E/E/"$F-8$"%?5H,C&!'F%4&19-9@5&2"%320#D,G1)+"%E:D)584,'&3
@r1286
CCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTNCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGNACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGNTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCG
+
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
@r1287
GATTTATNTNNCTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGG
+
*#&&*('!#!&+)$"!***((&+#+!''"%!!)+"&*$%(##**)%(!#((()))&!&#*"'%#$!#&"(#'
@r1288
NCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATNCTGCTGGCTGACCCTGATGAGTTCNTGTCCGTACAACGGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAA
+
#B)(1$%/D/1;)+.&"&"5$D%8H(7F01/1>;+!*D7EF/D+++%,,?*;,+/DFB@5=F!5C>+:*C#0-<">+=#$)2<0&)EE(%)AH7C663.@8$&D'D>))HA+(+?-47D@,%&B$A4&B&@"+3?C-=5$,#C<8:)D*83,84B#?6:?4G**AE2(7DD&.-:!@2.);A1&@)A%1.9&%D$9+)C65(84*$-2?DHG!>'+*6!E-;DE3#)C36H>=+F4#$%=E:#2?1FA@H:?>*HA"+,E:192(,"7.,-5?<A14BB".@>?9!>3?E
@r1289
GCCACACCGGTGCAAACCTCAGCAAGCAGGGTGNGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCAGGTTGTGAACTTCTGAAGTGGTNATGACGCCGAG
+
5=,%>C@$=#1#F3?7%/>>#)%*"D17G1:2HG<(4&H%-,)+8+C"'?%BB&2;4<348G&':>1*5$/5>15")=4':D3$9</'3:$H*G+.H88;9B-8,-B)>#CFB.G6*9C+4&)@"
@r1290
GGTGCCTACNNCACCGGNANTAGNANTCAAGACTGAACGCATGAAATNTGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATACTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAANTATTTTCCATGAAATTCATTTTTGATTATTATTTGAATCAATTCCAATTANCTGAAGTCTTTCATCTATAATTGGCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAGTGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCATAAAATNTATTTATCTGCTTGATCTTCANATGTTGT
+
)&)%'()%(*"")'*)"!("*!%""&*#*'+!+&+"%$&%)(*(+""&*#***!#*$%%)!*&$"**('*$%()(!(''!$''$*&&%##!*&*)&!+$""'!++('%#+&%'%&'$$%&'+&)(%+$+""%*$#%+*"#!+&(&)*#%!"#(""))+(#(""'&*'("*&&(*((")$)%!'*(!)$!)&$)"#()*&(''+($*#(&'#)+"$*)!*"(&()!)&*%((!&"''&)$(!+*)&*+$(%+"&&")'%+$%"))!)'%#"#$))*'&)+')&(&!$(+('+$*"+%*'+&*"&$$($!$*!(+&*"%('')#(#*!&%"+(!!"'(*#&)$))
@r1291
TACCGGTTTGCTACCAGGGAAGAACGGGANGGAAAGATGAGCACGAACCTGGTTTTTNCGGAGTGTCGCCAGAGTGCNGCGATGAAACGGGTATTGGCGGTGTATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGCAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAA
+
??*.,+4*A5B?D$91E@2)&5!.!8@%&G.D1D:'H,=)DG?-!'>/;G"(D2--&'!1!/G%,%CH3.61F>:G(HE)B3<<'&B2@<*3E&@E%9<+.!!,6C4+01<=G.!#<+9:0A22.2H%0E*-7&/BG=2(D2"?.$!'>H8C%"*6*/3-",%G?,G.B?%:""("GH982$>36>.+@B3'2%H026,/84/6;/0:(>H4'-=A=H?2>*!8+B%!$?>"?A(#'6#34>?3.<.2"E17G8,)BH(>,?
@r1292
GCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGNTCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCNAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCT
+
/%B131!"F25.'&!E08A7,32B*.$E$;*@/>E>&*7:8G<:A><,=?>,&B,E1.@93HF74@80&469B.%70<"7C:-!837!,EB(GB/A1B53:=0?G(B>7'FA9,C;6,%;2#*DA8$34?3A$C'=E4E5C$=<,$@;0B>;?5@((!:DH:(!+-
@r1293
GTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGANGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCGAATGTGCCAATCGCNGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCANAACCAGTTAACCGCCCTATTCTNTCGNTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCT
+
F239D=4EH$"53A;@5)<%A7*F476%4E&BD-/11>?5=-&1(<.<>#-$9B9-.(483!'1+?C==AC:G'7/,H6""$</*1"?*=>1)!.)E!::9:/489H<B)G"+4%(9C11C93HB$2H80;5D1*A@G?-@;5:!@?8&+6D?/*G9'4/8!?(A#6B>94'3*/2.*;+5&8/."7&('1+H""E@<;#E):2(:F04)6)%40(7/1$AE,>7:/3,HE1;+%H:7(&8B#:G6,@-?)6>&;+;B18#;;,##C2)+8)&/G?$4AF*9H$E*983(!6A(<F(!3('$6BD?6B9>C-*2?&;07#*DE-@..>B/?=H;<9%*GH'0B::;)H;%G++(BA&#??)24
@r1294
CCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTNTTCAGAGGGTATTATAAATAAAAACTTTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGNTGCGCTGTAATTCTTCTATNTCTGATGCTGAATCAATGATGNCNGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTNGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTAAGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTNTTGATTTCAGAATTAGCCTGANGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCNTACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTC
+
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
@r1295
ACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGNCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGNGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATC
+
#2"G%(1.=DA@27@);5G.12--HHC2)GD3C0=(7445?9$?E'H-$'&8(G%91261<9%8#B'<$7%HB.;%HDE++',F5D:5#-=,B,!/8G3*;6;*H6:,$#<0>H&;&#3(7=9-D0;0EF:9'@DF9#5>A@-83G"8=@3'1.4D5"")B-;8$4&0H&;,F3$%&++/+::%/DH7H"B.2FE9.>08(<-*"(/0/7$BA$!@#1#9E?C*7*1F2G>E:6=$09(30-$"D>!*C33E:H8%=@B9=G,8+>EH$4/20:)#$4H:GB=**1+!47)9'.:0GE0B>92)B!DA8#"-F0E&!&39()'EH1$4$8;)4;H3"3!7<?!)6.B&E!@/%)$ED:B4D85@&2F!?7!$)0"A?7C2%<(,$!G4)6/2H6*8%=&*+E>&'3F)&9)F:<>H7AB:9CA&%(8E,<CG&4
@r1296
CNGNCGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTNCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAANGGCC
+
&%*&$'++&!(##!#'$("'&'!&&))(**"+)'!')&+!$&!'#&'++"!"#'(&'!)$(("#)+(%%)!'!&'(*&($)((&*!&&!'&')+%%$!(&$"&(#*(()%#"!+$(!(!"!!")"+!'"%''"*"%%&'(&%++%#$)#$'*&"!%&&'!&!(#%&"*'!%%"'%*"$(++&*$%'*%#'*$(!"($
@r1297
AGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCGTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGACAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGT
+
528!<.,,H"#GCA&33AC)F0=-C@2*9:58FCF:>?'<B#54C"%,HD:A9-1?+7(>!3H?>>CA/9'E=&7(@.<3=)3@,9*<655.3-D9FF87&!@:HC%)D58@406EH#>"C)H0D;C.)9*3=5B$,2;!?:%E?+9,
@r1298
TTAATGCATTGNTGCCATTAAATACAGCACCAACGCNTGACTNCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCG
+
?!G4;F7H@'F+G;?B>F3!)1,2!%D%C=+'-3(-6*+,!?F"40"*=BB;-AB-8+'/.7$EBHCF%4"C5G<BD;4+#;C.F.:)0;*72=2C;7&7D'/6?&+F"8*#(G48>A')5.:E
@r1299
CAANATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACAACCAATATCNAGAACCGCATCCCACATGGC
+
*'"!&$+("!$*'$+($'(%&&")%)+$*+'!(&"###!&"(!"'')**)&"+(+'!$**++!#(&#!!%%!(*"*(#($#'(()*"&"&&$%"+'#(*!!#!+()()($*"!!#)%'&+(*#%
@r1300
NNGGTNNAGCTGCGCCAGTTCTGCTCACTGCCGGNCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTNCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTNCAGCCGGACTTCAGGCNTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTNTTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCGTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTNCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCC
+
!#'(%'!((+"&+"*(+$)+'!!%!+!)($('&'##*((*%&($%#)!)$!!)++!%()+%$!*(#(((!*"++%($'$'&#*"*+#&"*!#"!)%%%'$''#$*#+'%"#*((#*$%&(#'%"&#!)#&("'#+)*%(')+#+#$!*%%'+%)#$!%'!$*$&(!&#'$+"&"#)"&&*!$*)(&%#%%#$!)&)'*&%&(!)%*(("*!)+)*')"("#)!!'*#(#$&$'&(()+**&$!(#"!!$%$%'%'&$#$*+)(!(*&"!#+'+"&#%++*++!&#+)+()#')+**"%)%($!+)'++(%'&"%'!%*((&))!(!)$"'(&&%*$#())(**&')%#$#$)'""()%$'"*!
@r1301
CGCCGGGCTATTTTCAGATAACCGCCNCGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGT
+
<B5'/9+>5!43":0<CEDC=*C?)A96=4D=@=E06FD&.!-10;7C3*)=90$(2:'A.'/8AE=)B
@r1302
TCATCCAGTGGTCGTAGCAGTCGGTGATGTTCTCCGCTTCGATAACTCTGTTGAATGNCTCTCCATTCCATTCTCCTGTGACTCGGNAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTG
+
-<9H%/C>6@BE/=+;G<:(?8F$"#1(01%D*;?F,(D(516#8*@3/,,DB$@8B9H.'?B<;94>>><8>7D,((%1D&".3=HBH(*G/G#.E/+314$D)D#4%$6<AB0'+C2=@5.;6!92%!,B=D&'A2/<D.+#H50#!=2@;:H."+H(<?)A.2!+!//958;)$$3E+DB@-F<&<F)0A((11$!H2&&*5,'D?4767==H$;1$=&;G*'&0092G+BG7-8B0C?C-<;"+,B(A'4?9'++G&)EF-;)112A$69$).7!
@r1303
CCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTA
+
/9@5"#H+''F9$'G@@H4@=(=$7?3*1$+9.G')GF4(>@?CE/(4G'+;4D;2:1BH12:$*?A2G<<A)>+9G'H'!,7A2@06)+=>?&=:F)F>29!EG:<9:;0B'?35,8;"D6-"$6%D)G/5.(=<-C:0G7
@r1304
CACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATC
+
52:5+'!#&:C0'..H?+#%#9!"@(.7>&,76D'=HD/G"=C+>6:E)++70@*.!A>B8>H"4D3A.0(0H:B.=?8F
@r1305
GGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACA
+
=+1"(%$5>(!@$'2#0=AD3&.%6);&E@*DD5+7A6'*:3!''G)G*%AAG6'C1F$9.2*B5G*D)".:CB&@F&'.<(+G!)3@-/"38.1"$CD-$/1:3#9>5=>3;HD$<6(@
@r1306
CTNAGNNNAANNAGNGTTNCGCANGNGCNNNCAGCAACAG
+
'#$$&!!%)$#$(!%'!#(%'!%$(""(%)++!&$$&&+&
@r1307
CATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTNACGACATGGGATCCCGTGATGACCTCATTAAAA
+
!-!0%.1E6<4+F-6?.',?2G<*G:>B;-64-7&0&*'-/,=32F.7,*/1H5&,A@)@F3C,*.H8,,.@=>,"G%1""$0AG"7"/?-'H1'("1H+"/.&':**+,G$+G;<>EEAE=<0529;&898,3)+
@r1308
CAGAACATGCGGGCCAATGCGCTTANTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCTTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCT
+
@86&G2:'<=E<(4(4,"$;(#&*+/29,->:G$<!93E)$E$(6C.)#:FB8FB)3AG@6,#E<:/H:/;/!%9$:)A+$5:52:D+@?18>CH5G#$7+1$!H>+93:)7/,3":<93*)G>F/2.%2F&-(E337!;H;,(!-'"83F(D.'/8"GD23('
@r1309
ATTTTCTCTNTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTGGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGAT
+
#>B.B+'40!<=1="?9,$'#0=8??>A.8,;FC2:''<2>+4(.67D2;9H-4EBD,)?GC:A0=BH<<36@@0=3H:-%?%+2,=;198=F=186"*<$1)+7(!AH$484#C&751<+BA>,<<=37=#:9C=CC=.);2/C.BEG*2"E+?85F*8&0=H@@6@(6-18(3;:#&G#!896
@r1310
AGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGTGAGCCTTCCTGTTCAATATCATCATCAAAAGC
+
1;%9+,7002'<2#+/B:D159@.>(?8C!/67-D,1(2)C+)6>?5H:)4F*+B5"-)!D)=:B*=8#7BC?21/GHA-3(,E8,.G'"C#</A1/<160.E)*!8176G=+E0"C7
@r1311
ACCCGGCCTCAGCGCCGNGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACNATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGNTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGANGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGC
+
0#(7@?$?#@?>0C<+)>@@A)8DA<%H771.0F-.$-;CBE+=1!<G#'(-A$'6'&)&5<=9#(:5@!9F/+->>);H;94+4*:+2-:-H"8/$4,05A:09%5C<"-)G-DB-#-9+$65.2,@09;="E3>@<AGH,.'!G1)C,02%(#@5'!9?*.>9>4H"D4:>E9552=%#;A6A3",'6,,0-7,1&'1=$*D=:?;*9;AH!7/"&9"3':>/C0G?EG6,E<5=@&)F<B-;&1C0A>=BF!!%24%::,=B7!$)@A1-0"A6F!0;0!+@@96EC1/"F=?$BH;FC,@,H,9<96B:#"62E2'(DA69D0/%9!#E6%23F/%HE==#G.>"$,C$AC-H!6
@r1312
ATGCCGTTGACGCACNCCCCGCCGCCGCTGTTTTTGCTTCTGCCGCGGCAGAGGNGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGAATTCGTCTCGGACGTTTTTGCNGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGNAC
+
%+&#&%#"%$*)'#"#())%!*($#!%)##%'$+)%)($&!'$#*($#$)"#+%+(')()&($$%(+$$#*)'&*%!*$''&'+"+"#$'!"+$#!+%)$%#"$'('%$%"#)%++$&*!'"(&))$$!%&)'$*()!+)*!&)'#&!+(!''
@r1313
NATTGTCGAAAATACTGCATACACTGCAGAAGGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACANGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGNAGAGCAGAAGGTGGCAGCATGACACC
+
"&-*#&46+-%*%51A>>'G&'=//;2@*,D+")04-#7:#>46H+8F9=C/&A//5#'7B7C/-".=8FB-=53GC-0'&C8))1!*82A;69,3G&/71"G1>79*/*#%5""4$4CB$/G<D!4(#H%6&))6?)&8/BG6?,(#!#%*G<'(G*7(B6C/>B&=B-195*2F+CGH)1##)"5DFH!6@@?(*4/<++99!(C.()*.C.>2%HA;%-5A30=%#A,2=24D"-;#"8D(>#>6'/>DH--E%/<A
@r1314
NGACACNACNGACNNTNTCNTCGCTGTGAAGACGACGCGANATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCG
+
""'##$#"(!'#$!&)!!*!+%"!&*"+&*'"&%%!)"(%'%*(+#*(+($"#'+"'''$)&$!*#&*&)($'%$'!!*'%(&*#+++")$#)%(&&*&$"'**&"'"%!
@r1315
GCTCAGTTTGGGTTGTGTTGTTGCTGGGCGGCGATGACGCCTGNACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGNCTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACNGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCGCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTAGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACANCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGNGGTGAGTCGCTCATCAT
+
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
@r1316
TATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCNCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGT
+
B5+GAEB5#&4592#F<:4;14$A+#3-$=40$+962>>'?;C/'@>.C29*!"E5!44!1G91+1B>7;,'G0;1./A%@1?$+6"5,-=:<G$@.5=@)6%<7"*8C/+9-$(24A,8?(0!!?
@r1317
GCTCCTTTTTTATTATTCCCATTCACCCTCAAGCGTANTAACCAACAGTTCAGGGGTTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGNTTTTATTTAAAATACCCTCTGAANAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAGTGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTAGGTGCGAGTATCCGTACCATTCAGAANTGGCAGTAACAGGCAATGCCCGCTCTGCGAGGCGGTGGCAAGGGTAANGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCNTCGACTTACGCGTGCGGAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATNGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCNGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGNTTAACNGGCTGCGG
+
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
@r1318
ANGCTTCTGNNGCCTGGGCGGTAAAGAGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGNTTATGANGAACTTGCTGCTTTTGATGATGATATTGAACAGNAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAA
+
#"(*(("*$#"'#+**%'*"!#)'&!!#&*##))#&%&!+"$$+"&#)#%%)"*'*'***$+%!&*$('(')*"$)"("((!")"**("*'&"%##)+!'&*(&%#+""#*"&)*#&"$++(!!*%(#(%'($&*%%$**$#%*)"'&")')'+)&"'))$*%(!*)&$!'+"%($%&('+"#%%
@r1319
NTTCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCNACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATNATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGNATAACAGAAAGGCCGGGAAATACCCAGCCTNGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCNGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTNCGCGTCACCCACATGCTGTACTGCANCTGGGCCATGTAAGCTGNCTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGNCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTNTCGTC
+
"(!+"&&&"'#)(!+")(+"*#!&""%+#'%'%+((#!((!(&'#)+)&!+&##"%$'*#)*"%'))(*$"%&+'#+#$'%(*%()&+###+&"#(%#*+*!"(%)')*$")+#*!&"$'#!"()!'%((!&++*$!%)!"()()*!'&'&+)&"+&&*$##&""#*"!'*$&"$#(#$$)!%'!(&'%%##&)$(+)'("$(+&+%'"'&)!&&#'&&$**&'(*'%)&)('$+)!*"+++(##$%)$**'+"$%'#%$$'$'(+'!)*)''+(+)$%%(*&%&'!*"*&*"%$%&&&"$*$+'(%%"*+&!#)()*"'!*!*"*%#*)%!(('$&''$$$!(+%&(!$)#()"!&*!#'+#+*"+"*"*!'#+)'#($$$("%#%*%&!%#'(*!%)*&(')%*#+!#($%$#$+$##!'(("'*!$)&*&*)%(%#$$&&&)'')(%$%#&()+#'&%!'!%$)&)%'&%'""*+($)%"%"%%#**$'"+'&'+$)!!"%))'&(*'*(("!*""(%"'*+!*&#'%*&#$(((+)'+)#)$%(+"%")(&"&)$"(+))*$&#%)+%%))++*'(!#**&+'%"+*#)%*(*$))++))"%!#'"+')#&#$+%!+%#'#*)*#)
@r1320
AGCNCTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATNGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGACGTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGGTTGCCAGAATTGTCGGATTTCCA
+
%'&!+%&$"+#(%%)"+%*''#&'+(()+"#'!(***%($!+$"*"(%&#)&'*+!)('+$%%!!$"''#(!!"*#&"%*+"'()#"#'(&'$++(%%")'$!"'##)%+%+"#!!)*&('!&))#%!'%*)"%!&%(+'+"&+&*'*)''#*(!'++&$#&"*&!+'$'++!+&#$+')#'%"&(!&#"!*)##)(""&&+!"%(+!'(!))((%'++("#!$*#$!'+%+$(++()")"&&*'#+#(&))'"!%*#*$'#!!'%))%)##&%#
@r1321
TTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGAGCAGATTAATNACAGCGGTGCGGCGCTGGGATACTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGCCATGGATACCCCGTGAGTTNCCCGGCGGGCGCGCCTCGTTCATTCACGTTT
+
/E.A:*B<$6=)DH?4=<?>#1%1DG;'F4%!:(AH8%C0%AB!!'E3://)2+-B>.;0/.(0F@D8%&235@:G7;(&B,(1;2!$B3.!.1%?!6,758%@AA5"4@F,2&:;@-(15C&7%9:@F@C=>=!.BH5H?;CE6*1=,%&-A@<1E,<156@?.8=+49+4"A49*8?."FGA)D)5'1=&?@!D'5):%,H$=FF:+;+F4"=@6:'
@r1322
AGCCCACCCAGCAAAATTCGGTTTTCTGNCTGATGGTGCGATANTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTNTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCNCCCAAATTGAGGGNTGTTTGATCCCTCGTNTTAGGGGATTTTCNCTCGTTTTGAGGGATGCACCATTCTGAGACGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTAGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCA
+
+'")%!&"!%!"'("$+#%($!+&$(*)$%'*)"#+!&%'%'&#)&#"&%*)'%"##$"(('#**"%$*+*&%!"+)*&("'((((%(($#(*!$)%(&%)#$!%%#+%*+!$'+*(**+(#&(""*(+#(+!%'")($$*)&%'#**"(%($#$%&!#)%!&%%%#%+"!+(*"&##$#'("!")$(#+)(#$&%#*)+!&$*'''+$'%*!&($'#*('!!*$"($#)))(*)$&%"&&%!)%"))$(!#$")"#!!$""#&&'&+!$)'&&!"+!''#%)(!)+(%%()&!&'!&#)'&"!%!&$%'%())"#$&))!&%%)*(!%"%("&*+!$)+#()+)&'"$!&!*+"$%&#&'!*(%('*#$%'+!("+#!"!$)+'$+*()%#(('*&*%)+'$
@r1323
GGCAAAGTTACCTCTGCCGNAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATT
+
21%F4,)1%A?4D<89G6)75=,$787,"'%*?494B*)B%-#49-02E#=1.'2-!/6;'';:)(E83E"1+&$976+00$%@::)1=+06H2<==-+%%C"DC,A;7B5,51&#5(0#,*84C(DEB)@<,"<A"11/".>0<?H"H<BA.;BB!:@)&:+-H#@!15.CF8%44D-A%)$5'/H!*$"B+)#5#"E
@r1324
AGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAGGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAAAGGNCAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTCTTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACNGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGANGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCGTCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATNTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTNCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGNTGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCAGCAGATCN
+
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
@r1325
CTGCGTGACCAGACACCGGGAGGCGNCANTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCA
+
B+*=,;GA=6D8G8--"%A,G@7!58290:=,.5"@9;/5@'B)7DH:(7"="91>;?3F#*#:<5'5,7>7><3EF-(:3?G8%G0CHCE8*+09;2F%$)4.1=&:!EGB;B3=
@r1326
GAGTCANTNGTCTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGGAAAGGAGGACGTGTGGCGAGAAAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGNAATAAA
+
%'%$"""%'$(!+)%+!$+$)&"!$++&*!""!$'+"#"+$#))##!((&+'!(%%'+*(#!$$&(**(*)&%*'"(##*&!(+$!*""#'$%("%&&**+''*"$$"#$%%%!*+(&"&%(%&)**+++(!%(#!'""'()"*%)%!!%#%!
@r1327
CAANGGAGANTAACNGNGGTGCTTCATCCGCGATATCGCAGTCGGCGTNACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTNGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATATCGATCATATACATGNTTCTCTCCAGAGGTTTATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCA
+
''*!)*&!''(&#(&($(!%!%&&+#")"#(#!&#)"%#!*)!!)*!'+$'(&%%$#&&!)%$##"*$%"%$"(%(!'+&#'*&!$$%+!%%!&'#$)(*($'$$"!$*)+)%!*"!*#&!"!&)#)$'*"*$&#"%))(!!$$*(%*&*'&+'&$)+&))'!%$(!#$&++!(&!"#+#"'%)%$#+"(!"$*%#(!&+(*'+&%%&&$&#$&$%"'&$#$)#"%')")*$'$*$&+*''!$"%(*(#$$)"'&*"($!!%)*!*"!#'#"")+)&'!$$#!+($#)&&*&+&+&'#""*""$""!("!+()!$*+"*"##**"')!#+#%$#"'#((!#')'#%+$++&!%(&"#("&+%+&*%###'*'%$#%$*$")%$'!(&#!')*')!%)!((!!)+($%%+(&)"&"($(*$*(+%&#+%(#*)('&(%#(+$'$)+'++'&#(!&)#))!$#*"*)'#*"#'"$&$)()&'&'#+'#!*($$*
@r1328
CTGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCT
+
'"+"!#)'""%'+#"'&%!'&')'&**(&$!#'))!#*##$%$*"+&(+''"##*$"!((%#*%&#(")*'"'%%%*%
@r1329
CGAAAGCTCTTGNCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCT
+
D$,4%C8)5:;3")*46(&F$.C&B;H,9F-7?*>?.7-=43-G2->%1F3C$:>F039&E4<C8F1C/HE%'4B49&83:A)&*A5!*D8#6DD(/4+"*DHC.#,)96%F8C;$8?F7'>H@C+!2?
@r1330
ATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGNCGCGCCANCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGNCTTATCCGACGGTCGGTNCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCNGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATANGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGGACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTCGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTC
+
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
@r1331
TGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCA
+
1*'$)'4;0@G6@04A,#61F6#;)CD)-"#',*/H3/?<=(50&C)<G9H<7%,?1@"%,'D.?G34>9/7-1<</%A+E8GA+
@r1332
TTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGAAGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCTGGTCAGCGTGGA
+
B8@(E%G/?>'9+=&:)E=0H:?A.4='H(B"D6#(;:(5$.20+8&?'79.)+A/C+AB0HA"*A$>158E$%$.;A.F4>.C7D?DHA:#(8-5(+842$EF@@,;0)AF"6&FG%5!.=.@DH)G/H6@7BH"'.)!E765)#$14(+/56;C7++8@:E=29--3&/)/1;-8G*.G&"')#H6%"::5>FH+)8"/B2@H=<;;.43<=(*452=&+?$5>DD$H5A37CB5*E*G1ED.)<A3.:B==B)#&-&%F.0.ED8;$$6B?1H$/%.HF:!C"1.%*A5D?@,C%2.19,4:/5*?(:)=H5/D/BC4(-=6*E+,H4,?7A/DH1;1:<A->C:.4A%H0?
@r1333
CTGATTAACTTGGCTGACNCCGCCTTNCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTG
+
)<"+B;1:365G6=0A&@E!D24&5?GG%4:G),G8D!@%;,F=C2@4)&2'=?*D$.00%96:@,&":.#5'?7(%A&0G4?1CF$'?!9$F((@':@73"=E!!(<$F;*?1%94:-5)AD$+%
@r1334
AAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGGTCAATCATAGGTAAAGCGCCACGCTCCTTNATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGNGGTAGGCATCCCACCAACGNGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTNATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACTCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCNGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGNGTCAGTACCGATGTAGCCGATAAACACGCTCGTNATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCNGGCGATANTGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCNTTGCNAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATNGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTAT
+
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
@r1335
ATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCANCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTA
+
$7HGC/F=89=#D.11H*39"A/0(*G:*D3.0=D*H9&B35=#">(#-&;#,,(4668"%*:5;$"3+<*$+8G$?H4,7B542AA0$!!=(DB&".6.$-HD'2*%D5$DGB/*4603./<6418@C$(/;/)2#+HC?$*HF;'F5)"(1C?<>=2D0E6;(F,@
@r1336
TTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTGGCTTCAATNAATTCTGACTGTAGCT
+
+'(*!'*$#$))"")**+(+")""*()%+%&"#*(%#"(+&()(&&#((!)*)$(((#*''%$!!$)''$#!$%"'"$"%%(##'"'&*"!%*'#')''"
@r1337
CCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCCTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGT
+
)>%F'%4%(A0@;**8*&?(314B56H-A,),)61/?@/FH)*&C=93=/"'>%?%GB<B=4H"92#A5+A)3<784!#H7,#,D7=2"A-/G$2&8)259@&7)&DH!!"(D2&5F@H7/??DG-<?.
@r1338
GGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTC
+
7,#G.GBD.H+&9&2E:+5"E?67D;C69*""''(:-F/(4;7>=#0+5"70$G?0.(;D4-9.))A<!;%"--5/+0(@1D4(-#A=1#A$)!0(-3DE;,2=G6E!B.3?<-%.08&1"F@E04<FAA*=8H'G)+26?4/C'=>$<&*G3$16CC5H>37?B6B&H$,-A>73(@24-&$?(="2';8=77B&5<&;%
@r1339
GAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTNCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTNTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCATCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTGTGATGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTANTATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGNANACAGGGTTTAGCGCGTACACGTATT
+
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
@r1340
TTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAAT
+
90;DA92%%G=/$&&(H6=<&2/*.$3@-:=E%'26A/780;,.0>*H08-:B5+29(-3>91A)#6E!.;D4FAH"#G'HD+%E,)DA(CF"@89@812<
@r1341
GTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTNCGCATTTGGTGATCCGGTNCTGCTTCCGGTNTTCGCTTAATTCAGCACNACGGAAAGAACACTGGCTAACCA
+
;,&B4A5!BB2-0A,D9AF0&2<(<2.=#*8%-/?85/@+B:C4(7$"%6D-F&4"3'*"GE9AH/E=-$2+(G(?D0%8+=%2<,;(CG&7$>7F;(D1(E7<(0(>(A?3
@r1342
AGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGTCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGANATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGNATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCCAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTANCATCTACATATCACAACGTGCGTGGAGGCCATCAAACNACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGAGACTGAATACGNGGCAACCTCATGTCAACGAAGAACAGAACCCGCNGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCATCGGAGACTAACGTCAGAAAAGAGAGCATAGACATCAATT
+
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
@r1343
ACCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCCGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCT
+
#)9'3G<;2AHB*496C%FA67GD(DEGH=#&D?#:6DG:?7799&&"5::2'3<C!05'7552$@?,7>*F<D0&C/G@%("H?%FF:):B=71H>.?8&D"8"77<3";"H.5=1*+>D3F84'4D>/1A/<!*B:=@*&(E&A-A@:07<>=?(1#=(FB98G?*5<2=AE..56?4)8.+:6"E:4:8;D@*<>&@E%.BEHC&/->@;*+#<B4C=ED);CF6D%!%D83E'0$(D$"6.GHD8(?53%D?>>86-5588.4#<+)!"!-&,@0>*?(!5B96H<?FC$>!%A'<1;#$A'<-;9.<B'=<&!%?-.:"A.!>,H8&&F<:7?$G!>58(!H.5,<"C;<<E$1!4%?,E.,1<1%?"F<>00&5:*8F)#;:)4$$7(BF=$E=689B<$*
@r1344
ACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCANAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGTCCACCGGCGATCCGGCGCGT
+
6C)(C!7!%FG#+G%%/5.-1E5,E3F209,C772#@%+.)#479C6/16247.2812$D<1>D$C%/!+$H.,0H+5/*>5$?(CH=%#<G2E810;2<82*EG:/:"*G)G$)*7.!;@:
@r1345
CAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAA
+
(&,$38$GA<A":*7->'EEF78$+:.#A%B4)!-"C#4'G=5>2@=EB835$:9?3;2>;DHB(+@20!A$&&2"H
@r1346
CGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTGTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCNCAACNGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCAGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAGGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTNCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATNAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGT
+
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
@r1347
ATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACNGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGNCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCANAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCGGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATANCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAG
+
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
@r1348
TCNACCTGNTATACCAGTTCGTCGCGGCTNTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGNTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCG
+
#&"*%)*&!$+'+#''"(")#%"!%#"&%$$+%""&*!(+%*#)($)!#+"'%'!$))!(#!+%+#!*!&'%(+!)("#""+()*)!)'##++%'#(#&&')%"%#$%"*))*()&%*!&&$&!$(+'%!+(#!#+!*!**""+$(*&&&(%%$$'!((!'(%&"+(%')!(##+%%&"'(*"%("%'"&!"*$&"!'&*'$'$'"(((
@r1349
ATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGGTCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACG
+
,%;B"&+7?G7/3B"'A)0?8+)>A=>FE*=FA@,0;6(86;6&*$F@7+*5AD+F,6/8+D<C*E2223C.F>"6/G1&9:9*$86"-4/3.<3*G,89EA93-$5#(*-//(.,($?5(;FA!1/">,.2@*D,3.':#(H5?9(8)"41?23;8"884B<(:7A?-994!5D7FA=6C@#5=!(B8(56,AA?#0=7A/
@r1350
ANNTCAGTNNGNNNGGNAGNCNNCTNNNCNGNNNNNNGCNAAN
+
#!!###$$"!####$"#!!#$#!!#$$!$##$#!!"""#"!!$
@r1351
CGGCGTGNAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTGTTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGTGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGGGCCGCGCCTCACCTGTAATGCGTGCCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCNATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGNAGGACCGCCATAATGCCGTTGAGGTGAACTGTATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTCGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGTGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTGCAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGGGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGT
+
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
@r1352
ACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGNAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACANTGAAAAAACTACCTCTTNCAGCGAGAACTTATAGCGAAATGCTTAATCAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATCTCATTACTCACTTCCCCACTTTTTTGNAGAAAGANCAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGANACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGAGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGANGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTCTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGNAACNCCGGGTGCTATCAGTTTTTATGTTGAATACCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCAGTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTC
+
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
@r1353
TGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGANTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAACACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTNATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTANCACTTATGAAAAANGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCNATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTA
+
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
@r1354
CNAGCCNTNCGTNGCTGGCACTNGNTCANTAAGGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAATGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAANCATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTANATCAGCGTGATTTACACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCNATCATNACGCCGATGGAGCCTGTCCNGGCGGTCTGC
+
)""*'*")$"))#(#$&(%))*#"!*#'"&)'+*)"(("'%#*)+'$+*!#)"*)%#+$("#&'$"%+!()#&&*'!&%!!%)'*)*&&+(&+""*$(#''"((*)))&$)*'$#&*"%%$#!&(&)%&%)#&)'&%*(#&($!!&(*$#!()&&"+"#!")*()$)&#$&&&(!)("+***'$'!&"#+++$)(+%#+!#'&%#!($((#+"'!*+&**"&))&##'$!"'$)'"*"""'&'(!'))%#"%%(++!($+$%)$&#$(*+'#%")"'())+)(+"("(&+"%%)&#$)*(%%'+'*%()%%()$%#("%+#$%)"$++)#$'&("%*$#('*(!$#(!+'($'#)&)'&&$*(%#)"$!%*)#*"+#+'"$%*&'%(#+"%)*+)$+'*)&&(!)('#+#&)''#$%"(*"#(##'"'#'*+*!'*"#")+#%#*&'$(&*!#+!&!("$""%$!#
@r1355
TCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGNTTCAGCGAGAGAATAGGGCGGTTAACTGGTCTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGGCGTGTTNGTGNATCCATCTGGATTCTCCTGTCAGTTNGCTTTGGTGGTTTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCNGCCCTTCTTCAGGGCTTANTTTTTAAGACCGTCACCTTCATGGTGGTCAGTNCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCANCGCAGATGGTTATCTGTATGTTTTTTATATGAAGTTATTTTTTGCAGGGGGGNATTGTTTGGTAGGTGA
+
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
@r1356
ATGAAGNCAGGAAGTATGTGGTTACATCAAAACNATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATANAGCCAAGGCCAATATCTAAGTAACTAGANCAGAGGNATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTNTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGGCGTGT
+
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
@r1357
CCTTAAGNCCNTNANGTANTGNATTAAANNAGCTCAATAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATNTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAATTCCGATTTAATGAACGCAANATTCACANGCAATGCGTGGTGTGCAACCAGCACAAA
+
$"%&!!'$*'"(!!!''**%'#)&*)((%!+")*$(*%%())'(#&'"+'""%("%!!'+'!&"'!(!!'%%$%!$!*+$)$'%!(&'!%+')&))%*+&"!)*)($%&"()*()'%%#(!%%*#*+))#+"'(#*+$%!$&*#!&'!%#+*'+(%!#$$&)!"&&++)&!+&$)$+%#+(!)!''##+$&!(&%#!$(*'(%$!&!'$#&*
@r1358
AGCCATTGTGAAGGCGATGTATGCCGCCNCCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTTACCGGCTGGATT
+
!?2C1B#"FC5?D.BD/8#,;DDAG:H@.?&"E0,A43"AD0@<%G!#9B$,(F'!D/H4"E&),*:<&/7D7.+G'1"$)+7/>2G;:7;F0-2%?)F"9F+E<->F.G/-11G.-9-0?
@r1359
TCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAAACTACGAGATGTATGAAGCGNTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGC
+
%");-'+$(!=@B/=$/)0"+D%A9(B"?H-H(65&8<">F'3);6,GF"6/873%CC&B!.+A$H%&*2A"3/<GGF1<DG*G2B%7535!2/2G1C6,A8-.:C:(1D4$'9&")*)=6B8@/B>%-<"'0G@(9EHE"B"A(:F'0-7,F8+!C14%E739)F!/C)G%4@2@#DD(5%'D.>40E*
@r1360
ATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTG
+
3%8*51B%>+8>)40.607;=%/'GC/8%0FHH&%1FB$>3>68%=C.F*%B)/H2$$-,%21:E6$G440G5$74$%+>;2=B>#C='4,6,'44736G98$**2#.8?E.1=,H"AC;)=G/;G/D>">1G4.:=(52%HB:)H%C.
@r1361
GTTGTGTTTTACNGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCNGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCT
+
)(*'*+%$%+$!+$$%"*(")&$"++'&""'$)#''#&'#+$'*!%"'(&*"(!*&""$%&(!*)***($*%!+&&**'#($"#!*&%*(!!&#)'&#%*"!'!()&)+$*"$+$&"!'#%$##+*!!"&!+#!*('#$%+(+"*'!*$+)('#(!)#*')'$&($*!))'++&"*(#)%!#()''*)*"%+""%&(()&$((""$&(+'!#+'!#''$+%++#)!&!#%)%&!%(&"'$('($%'(##%()$*'!+*(#$$(!+%!"($++&&+(*+#'%&
@r1362
GATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTGATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGT
+
8H5.<3%46!E86B&(G>,#E)?="&1BB2;!D6;A@C@@$6A&-8H%6!$*/(&?71B91,8&*:F:7<-CF?FE63A.%7B0H3*A+G'D4C6<0:*(=7(:<@7"(F*9BF2%31'?9E?G-/'"3&:@>:,>F'&<')A-,B@8>/GH@/ACHA?*A,,#%4--"G,"F$&7#)7#;$'C&>25E'G,4D5:A0#())H;H:7"3+&A7'0-2:'268$E9,68B=)"*6=
@r1363
GGNTACCAGAAAAATGACGCCTGACTCTGGCCATCTNCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTTATACTGTCATCAGCATTNCGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTACGGCAAGCCNTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCTCGGNGTGCGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTNGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAACTCACCGNCGAACACTTTCCCGCAGAAACAGGCTGTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATNCATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGNGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATNCTCAATGCGCTGCAGGGCCGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATANAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACNAATGACCGACACGGTGG
+
!(&++$)%'""%))%%%$+'$&(&'!!"(%+##('#&++)((*"*'+%+"'"'+(($&#(($"*)'**+#%')$!+$*#$*)%%"*$$"*$')*$')%'&''$*!*+#%'%#''"+")&#("&'#"#'&*+*$+%#+$*")+(*%(&*$"#&%%)%(*&&"%""$"(')"'*&$%*+#"$*"+*")!(#$%%#!()%%+')+#)&&!%)#%"(!%)!(+#*'&)+!"&*$'*%#!"#!*$))*'&&)'%%!'+&)%*%*++*%!#+&&))#!'(%&%&**$"#!($#&#!(('&*(&#"$##($((###"!#*%(#)'+)%$+#!$%%&)!&$$#&*&#'#**&(**#"(**#))&+!(%#('*&%++))%*+##((%#&'#(!#$)))#)!&'$&#!(!#%!&!!!''*)$&#+#$!!"(**""')"*+&%%!!#*+*"!!%$")#"'"$)'$+*((#'"%#"'#(($$))+*(("$!%!&$")%)!")'%%'*##**!%')%'%)(*%&*&!+&"$!*"*%&$(%+!('&!%$++*))(!#'+'")*!(%(++'#*+!!*'"!!#$$$'+*&+))%#&&+%(!%$#+&#!#'#*#!%%*$)()''&)%!$$"$*$(*+&(%&!!'(('*#)*)+))&!%)$''(!%")%"(#!)"*)#)!)!"')"$("(+$$*(#(&#)'&&''$(!#$!+(*"!#$#*%*#((!%$+!+"$#!&"*&)*"%%''+%+#*'('#&**((+%('!*#$'"")'(*'&#)##!%*$)'&$&#(*&!!$&(*'$*+'%((#(+*"+%++#)#&"')$#'%&'&&(""!*(%"#$"!))%((%$&!"')!'()%*()!"'+&"+'!%+#$%!#)##)"$"')+(+++$!**(*'"""*%)*&%$!*'%#)%&**'!(%($!+!(!#"*)$*$'(#(!!&#$)%'")((*'%'"()%'*!*$&+)"!##*!&&"*!$**(#%+&(*#'&*%$!%(&#$+(($%$#&!"$+'$('+''&$)"'*)!%)(*"")!$*"%&%'#'(#($&#"!*&)*)+*)!'&+**'*
@r1364
CAATGGCNTNNCCANGACTNTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTNAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGNGGGGAACCACCNAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCAGT
+
"*$(#&$"'!!)*)""*($!+**#&&)+)#('#""()!#)%#)&+#(+)$$&$"(%(#$%&))'(!&"+($!!!$#$#*#!*)"(!(!*#(%)"**!)$&&&'!**+#))$%+"""%+)!$)+'&!#'*"$%"*$#+)&(#$'+"*(#$+$&%%&#))%)+$!!!)'$#&*#"%#$('!#)')$%'%*"%##"$&'($$*("))##"!&)"'$(&%'+*'"+)$($")('#!&*%%%$(")+$*)(#($'!*)'##'&
@r1365
CCCNGCGNAATNAGTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCGGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGATCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGNTTACGGTCCNTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATG
+
*!)&%$"$%)&&$(+)'))'+(++!"#*&"*()#)'$*##*$)'%%"++"'$!&"$&&!%+#$#'$$))+$()%&(!%$+#"&(*$(#&&(%+"#+'%)(!&)#()#++*'#"(+"*"%#$#%'!##!($(##&%#'+$%*!+&#!&%)'%$$+"*+###*+)&')*$+)&"'*+'&)$)"$#+")"!#*$$&#(+%!!($+!###$*#+#*#%&+++!%%)'"#*'()"*++(!&%"&(&)"#$#'#'$"')''+'&$!#)!#*"*"""$*""+'()!"+")+*+(!#&#'%'%$+!%&#!")&+'(+'###$!"!"(%%!"!(#(&*+&"%$$&$+(('###%&!)'#%"%)(*!*+*"(%%")&*(&+"(!"!$""!&&**$+"!)$+(#'#!%)&+##'##$$(!)")"&!%##')#+*&"*!'$'$##'&'&
@r1366
CTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGANTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCA
+
/?'7!20>2.H!<42'A#B;G.!C=3F1152$2'6"5:#FD&*2?*7;"2(?%AA8@>(>53G(;.*A%!C;>;H=G!4::DF66B-4#-B1/:26/>-"9D9F"H@(+D=)C,3CG$GF?23?&(*0F84:*0!BC:B&.18+3:&,2*"7;"+79<)>?6A!E6D6!.=0<:.+
@r1367
TCGTGGTGATATCCGTCAGGCAATCGACCGTTGNAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCNTAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACNGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGNCAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCANTTACTGACATGCAGATGCG
+
@!B301B=DD+";D=?)%>A&#2?)DD'(F24#@&6C@!D960+H@4*-8?(9$C=,%>)5"'?2,1($')+!4-<*4)F#+<!+)D";!*,A:C/*:B@-.'G"508(:G(685H4%A<H/'26-E+D7814'14D#.26>*B>&?'#?F=%3>?%2'H6B6@4&"6#F5+C=.26)8$>>'>G#-CD&G<5BE*1$#$-0.88+/4(#!(.?$-E97D6:-&>F*+70A,8H+:E+1"/%DFB)?$)&7151+9C(5B7'=BE'H!D#30=7&-:@C@?%"?A#.G'8:9#'*H("':'=.&(#?#A!3%<!<!H
@r1368
GGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACNAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTNTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGANTGCCAAACGNCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTAG
+
-@3):098!%*B?C"GAG2?4'&.>=7/?8)%6BE<<0#1E50(&$%219*#<3C(+4$2A=B81ED3G4*$)A%+/1!95+51=./"H2F7=*<:$1>$E=B?A!'B#<--82+)DA->+A+.,9*71CD'+6F.5-7;B=DEF;<!25190"071B6D<4&&<H,+"A#A:;4>C<2)9473B#!"11:--&3(2$%AH92+B?3;212,1,H&224($F,'F27G0E&D>0,8#B2;A'FG2D?C;):;(9!)@-B*=3-)**@::F"=$@DA)$*-/-%45&0C4;"8(66.=#!)&<8==C:A"8F73:'-,?8:D4/G+/);-/F%&!G41H$0?3%7?E>*&:))8'4'/!<4<++<(0&$@"E)3:H:,!/9:(-<+!94-C;%5+@)+1-!-32;"3<4-$!6&!G-C+<AB;1AG"<8H'.<E<8'3.8&!0H.,?847+?+):GGG".8:7F#*.0C'5?8G5;8D+%-0?(,
@r1369
GGCCTTTGGCTGTACCAGGCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAAT
+
(-&'.E:#D97<#>C3/+:1#<E:F&$$>BE%?4)A1B=H-::;;C6D98";F06B6G:E<!-*F10"9GG#@3G*658<9F(30*4(%4:B7"GA)-7''GE)(D>"<A)>%!&4/-F3!#D3/1;!6)/;G020"GD@2
@r1370
TCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTC
+
#DE'+''H6<<#6"-:6=2<(0D:H<@+39;BE47;@C)1:)2;H"58G*
@r1371
GAGCATNNCGGTCACNAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCCACCTTATTCCTAATTAAATAGAGCAGATCTCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAA
+
'"&$$$##+*)+%)$#"%)")'&#)&#('&))!)#)&!!+'&"()+)$#)*'#+"!*"))$#+%+#'&!')#!"+#+$)++*($)*'*%()))(#*$+$()&'&*)+&'&$+)%&%$%%#&&'$(**&&(*!("&*'$'"+!"""!!%'%#('()%)('&"$)%$)!#('"(+&#+"%&$!)%")+!+'(!#'&'%%+*$#'$$###+'*+!''%"$(''%!")**(#)*')'(+$)$*##!%*$*
@r1372
AAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTCCGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCNCGCCATAGTCANCGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTANGAAAAAATTGATGGCAGCAAATCNGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATGTCGGTGGGCGATTTGGTTGATCGTGNTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTNTCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTCGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGANGAA
+
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
@r1373
GGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATNGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCANGTGAGTATCTGCATATGATGTCNGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGTTGACCGTACTCAAACATC
+
<003H!AD$HG-'33?43),'>G.F0.'F3)1GG/E,.B/5-:3+(.)F<(&.%>@=(?.>"<AD2F:.6-4BC09+1'$B#1?$:;B&!B&7"6E!<"0D?&52?C?%*-)$-D)3G#&+5""6E.9>&9)6$=(@#.23:;HE<<CH6*.D8,$7E*F*/4*7%3>!C2,$-,B+&)1+/%A3@&8"5'#77=1.7!'12A0#,25EH=G(!.%E<9/55.5C!=691G"8612&4B>A2$>22?"89-5@=?@G+=2-C8B2,349<)7$.+"E>.-,8+BB$>-D#&(59<7'9-;-?'-*D6>%=2/+7!8!1-;C7)4;/=G@#?610,$!?>H3:4*3>*E1>"**F8/#2#+='32(@9?3",4F<,?<
@r1374
GNNTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATNA
+
''"'#+$&")$%'%#$""!'!++"!'$)*)*"#$"!&$(#&!%$)%)*'"#+&+&'"(%$!++'$*#""!)*&$&)''&")+%)()*'%)#))#$)%$)*+&)&'+%$
@r1375
GTATGTCGATAAGGCGGTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAANTAAAGATTCGGAANGNCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCNTATCATCTGACTCAAATATTCCTGATGTCTCGATATCGGTAATTCTTATTCCTNCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACANAGCCGTGTTTATTGAGTCGGTATTCAGAGTCNGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGANGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTNTTTATGCCAAAAATAAAGGCCACTATNAGGCAACTTTGTTGTTCTGTTTACCAAGTTCTCTGCCAATCAATGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTTCATCCATTGNATCGCTTGAGTTGTCCACAGCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTC
+
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
@r1376
CGNCCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGNATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGNCCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCG
+
%@8:FF5FC;C:%0&0;4,F#$-E,0//>=7#637&26)!"-!2)G<-#"(<2B"8GE"'//D8&86B1"24D<2:!B8$E7@/@F/))B0*H/$<(59+=;(B4F/$-FF<*&*F33:E376<D#=1F#+1%#6:?60C"1#0"->5F);!$5;3&18=9@+BC*:B'5'2@-/A4/)'>!GB,"G6;!:7&1,;-B7H'>F29.H:$9"G"9+##7C$D&<=?AD;-14!;01C8E(,'=(0B#767H>-1B'#2)H'=%@H/(7%<?,1'.5;F.&740C)&)BA+$E@42&/0E@*5<3+/C114>*?CGGF9:0A
@r1377
NCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATNAATAATTGCCTCTT
+
$&;E1'*=;(B);;+(A4:(3%<0@0HBHE:D1:8=!862+-8E&5<'6/CC'."D@$>++-$3G2).?@=&#893?F')35-<!G6CG&<-E0A8;/:HF;<=6$B93<#+":F'&/%,H53@A+9>64E6D>%7"9(H:&0;264)'/
@r1378
AAGAAACTGATCAGGGATAGCGGTCAGNTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGG
+
(2?<F/&:$.9%3H$-,51E8,".;7-D6#E7,";A-)1;,(7-0>%.*'D%($EH:3!E/-H%':.!$>'380D)9%##4*#,*42?39-="9)/DE)D5G-&A$?8/E95$5D7A
@r1379
ACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAANCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAANCCAGTTTCTTGNTGTTCGCCATCNTGGGAAGACTCCTGTTATCNAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTGAGTAACTATNGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTNCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGNTTTTGTAAANGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCA
+
D"H5:!F7<;-);,-=&4!%*5;<2;H>/0+3(F5A4C>50".0FE;/=73'45#5.C6!.'2EA9=#A*4D2;":;A&?H->*!F$)78;2E%7?!@:/-2F0>-0$<<5(;@2&&G&,F<!H%7!3><1*0#19:C%5B6!%'EF9!G)G'@@D9//!C=4-??9>:@D@@4,@:/,,64&9C07.&$''<1-9;!3FB944-1B8$.$AB92D10A<"1'/1.:?@<!..D.,G5.*+&H%C%(FF!<5AGG!C',GB88ADGG1GE5;5.(1F">7#%&.@#%--54CD8D%H*A"20F;."5?)&&G#";%@!?=0,@,-H)#$/$9EB//)?3.!<8?9=,&E/A>$8/;61CFFAA',FF3<&@H*%9;A0!)0?/1%$#1-B8D:3"8!9G*%2'?7!#$H9:E59B+#$A'C&%;+2-?0?:)/G.8?$$=B>%H5,2;GG;:8#>/2'HA>9'>1$1!@-EF(A&+=6(G?1+;7.&195)('1
@r1380
ANCCCACAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGNGAGACGATACCCGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTNCNGCATCCGGACNTTCGCCAATTTTCGCCTCCCACGTCNCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAANGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAAGCAGANAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGT
+
%!%'(&+'')**!(#&!)%$*!#%$"*('("%!%$")'#&!+(+!%")&*#(())!"'+"+$'!'('')*$&!"&$&&)!'&!"*#$&&(*#&)!!+(&+$*&%%$$$)"!!&*)%#*#)$'#')*+''#*%+%"("%!$$%$"")'%(+*)"$'"(&&*%*(+"(+%''"%!!+#$$(%!"%$)"*#$+!)$#*#*'**&'&%*!')%$'"*!%+(!'&(!*)($$#%+*"%("##*+"*+!((**'&+%!&()(#$"%!)*!(&+#%&&(#%&+"$$%!"+'##(&&$#"**+&!%%!#%$!!+%+&$""!)&&('%!%!*$)*)**$+**%)"$"#*(%("%+&(')&)$&&)))&!!!+#"%!*+'$)(&&+(+%&*%%(!((!)&&#"(('+&%+&!#)&'(##!*)&(()+#&)+(&(&&!*')"!
@r1381
GATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGTTGNACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGNGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGNGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCANAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGNCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGTCGGTCACCTGGCAGGG
+
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
@r1382
ATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACAATCCCCTGGTTCAGAGCTGTACGTGNAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGTAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGNGAGCAAANATACAAAATATGTTATCTGCCACGCCTATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCNAAGGCGCGGACACGTTCCTTTGGTGATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCA
+
+%+)*&$+)#+)$&&'%*'#'!**)!%%*&!$&$*"!%%#&"*'"&(!"$*"))*#'$&()!&()"!#)$%"($*&'%!)*+"%!&+"*")!&$""$*!%$!&"&&+"+##&&##$*&!#!&$!***!%'%#'("())+$+%*&%'#%&$#"$%"(*(")%'+#!)+%*#"$)!()*"($&#($()"&**!$$!')$()(%$*+#$)+*!%(&&(&+"#**$+*""&!(&(##&"&*%$)"&#!"*&!$'*($)*&'(((+'!$)%!+'&'')##$+"&$#)%"$($*()"$*'+$&%#'$!("#(+*%'"++!"+(++'(&")($+''&')!*!+&$)!)#*$!)"&#('*!$)+)+#"++$+*'*%#&'("*(($%+(&&$%'"+%"$!'$))$*!'*%"&+*$"#%$'(#(%&$'"*$)&!$(%&$)!$$$"!%"#*$*)!%')&"((+)&)'$'+*(%$)$*$"($)+*&##""(!"!*"'$#*+$$&'$%%%+*'#")"()"
@r1383
TTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCG
+
C<2%?C"#&G3%47,&*<'@@2'-,<52;0>:B;$'F$1*F2'6+6FA;(09,02.;D8
@r1384
TCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGTTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGNTGACGTCCGGGAGACACTGCNGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCANATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTNTTAACAGCACCGATGCGATCACCGTCANGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTNCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGG
+
<F//68!C@?,7,=*B"/@;E9&>$(/#)=G.F'*H$)2E>0FG5*82%>E.%CB1)FD@9%4?)D.1!49,;9@:%+2166D-2/#'9.1<D&/1HD9A6/6?F.!?6(!40=66".2G)C7,%"730D+)H=7-D3!*=2599&?C-/-D'859.2.44@3&5.1CA)C%35,9#.%4,.$$B:==C(..!2E"38"?=87(A6&%&F*=9<5"/.EH@"D.*9/7;:3A(4@("?<=<7;9F$1)DC.!?;@/&-?3306@CHF,G.;(C-8;A)2#/>)%E#(B9%;62<AFB&E(C080?8A?0'&3DC7>>4"B'$%)%4G9G),-3&#B(AA@+E"/@#&)3B8&8>?H'-6EE)GC816G1&$='.*G#:>3(46$"497A44;%>3H)*F/@&*1"0='?$;+<8HD)"A%5@<+8951C921
@r1385
ACTCGTGATAANAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTNTGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACANTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTNGTTCGATTAACTGCCGCAGAAACTCTTCCAGATCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATANCACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATNCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCAAAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCCTCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCNGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTNCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGG
+
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
@r1386
GCAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTAAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTCTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACNGTTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTAGAAT
+
"8#/AA*40$H5)2,5GG59<G>.E2E!4163.121)<:%#DG.562C!BD!>>+1&&:2E4516FB41&E7GD+8&2F'AF(94+;;"@@76B?!@C5GG*;"H&E*1E!">BE=A52#00C1A)F(E'67"'F7$HB8012/2E<F.7#-5D?>+8$F*EG36H9/%H,)B#'H!F--?*D#/(B>)BA?*0/A>F6#$$*9,</7?G.5.<%G1H.FE4H?1),8AHDC&*2/AD86=C.-.'.-9G?6;;=?B!6E%1:5%1?>#
@r1387
TTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATNGACATTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTG
+
E+)BEFD-&*H>6/<6C.DG2G2G9HE;E(8*-?.$D(/DFB)465E*+<*9/7C:8%.C$)H?:<!+1,@,DB+C%##:,>/=2A,'"B;;$-1G=).)E"';49%H;,G=1/C$)3A-=+(7>?+GE
@r1388
GTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTAGAATACGATGCCCCGTTAAGNTNAATANTACTAATTTTTAGATGGAAAACNTATGTAATAGAGAGTAACTTAAAAGAGAGATCCGGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGNAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAA
+
03-7#&",.&1!@H#EB'#!1*!/@A$:8:;%'7&2C"CF("2BH6<D4-=BF.H:*&(0$E%2BC::(<$0=#!+/DC$A%',E24%;F;CF#&/>'2*H7.*;/@5;#<H-<&??,G4@=,8**B@%(>G;:67%.&9)3)DH/52))B#E=@(=02G!8<A@5(+E5FCD94$%6/D9)+=41?$9?,3&'H)3HE#(':;C%@+A221G.=)0C(A#>;-6&-*%,$!#G49EB'',F9:C34@'&'F;#!H&=%"9756##FG%E,+?0$=F+$GFC301/;,0!';%).HH6+<611@D%4G'14B%G&@&.#*:D3!&3#B.$03&9??%-<'=&'4G,?%%G5?6)G!,:
@r1389
GGCGGCATAGCCGTTATTGCGNACCAGATCGTCTGCGCGGGCATTGCCACGGCTAAAGTTGNGCAACAGGGCTGNACCCACACTTTCACTCGGTGGGTTCCAAGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTNATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCAAGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCGTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCC
+
:<;"D2213>?8@(7F'.;):$.D!>H(9=A4BE4FF9*-E6<D.$GC"2&(-/584AB#<)A54<=4&C<D460C98(,/=B2//&&;/B4,%#6<:A3*9:,9@BDFA!*D/AF276(AHG(2'B:.+D:/G2DF$*=1@.=.3#(<H,%B/0GE:C#7:C--#'474?5/B&'-&241C2!786D&.<(?&7;'%H+?.6><$%?&!8+-*=B+??E9++0<B%(A;*D"=:1<?;)=24DEBF=)1+GDH"<H<'AB,66;"7'G8:(4'E-5>;66:?"EFD1#95-*29#>8=7<(+197>(,8>H%?+BF(=6$(106A.C/>(,$'E2@)%""1,7E>;;F##(2+2>=&+,;078#;)E91.<H!9H$+2:54*<4.D)9"..D#/;&/B74?A=,G/C<0'*&"/A2;@?G20#%!')=F2C%=233)A8)F#$&:%:A&;-%/:4--,D.G<(6++@</-3767%E'+6D%2?0DC=
@r1390
NNNCNCACATGGCNCAGGTGCAGTACAGCATGTGGGTGATGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACNAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTA
+
)#(*"&)%)++&!'++&(%&!$%"!+&%%'$'!+#)%)(#"'")""#)"&#"+!*((("(")*!&%%)"!!*'(##"&#"%%&$'*!)'!'""&#%+(!($&#$()$$&)&)!+"$#*!'$%()*%'!$#*(%(+#%&*)'(%(%&!%$&$!%""#($##(#"&%)"$))%##$$+%()$*+$'"+'+%&"+#%#$*&!"()')')&"$*"%*#!%&#%)"*"("#+##!++$)(!%&!$'%&&("#""!"%!)!#%))(&$$$'!$!$*(%'(""(##+)%(*')"(%)%!%
@r1391
AGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCT
+
7>$F!:&$9.4?G52$B$'/5!47@4*5CC<,4E;+B&G(4HD<#015>,<&$A.D*3?095?D0F=6?<
@r1392
TTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTNCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTA
+
7-3E4!GAEB1+#HA#C,F@)E.6",,$)E&2GE):&0"6?5+&1B/E()!1&H0&)(F*D<=7%,?CF>0#BF(G!!.>)G,/H'-E=+"):9@F?/5=6:H%E3@*2"3#H@3F"4-?+@F3.G:HG=!9>#E<=&*4-&?46D7$C0":-&-,A8-H3"**,%0.8)A4!D?>4)7%G,E+$%0#*"5%7-,7#6(@3+724E271!3%((E(8-)DHA%'+$11,//$?$F0@F&?A',!-=HE+&://0.)CB70)
@r1393
TNTTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACAGTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGTACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGATGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCNCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTG
+
'#+'))+$"&$$$###)'"+$&#&"#!**"()+"(*"%)*)"!)$$*&'!*!&&(***%'%!+%$&$$'"&#*$##++'#+!"'""')(*'!)%#!(+&$**)!*%!"&%*#+''*(#+))*%(('($)#$$!#!+#$*)+)$+('(%$+#'$(+("#$$+#'*&$$+'$&!*(#+%##%+#)&!(&*&#&*#&!$#'"'$**($')'%$#*!)+")!+%"!%'$+$#!&('%!&+)&!')%*'(#%#'!*$$)&$)"&"#($*&!'($'&++*+$)+)#*)("$#*%($%+"**")+%*!!)&!(%&"''&(%%!"#+#%&"$!'%"))")!+'&!*&#$!#*$%#%%$""(%(%$'&*++*#"""$%#+"*)"!'%#%
@r1394
CTCTTTCTNTGATGAAGGCGTTTACGGCTTGTTGGGNTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTGCNCTGCTGCTTTTTCAGCTTTTTCGCGTTCTTTACGTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTC
+
)+')"')&%*#'!"*"$&"(%%%!('''#$(()$("(+)(($+"))*#$*&(%(%$!*+')&+%#%($)"!#+""*%#)"!(&)%((+!!%%*(%$&*$$$'%%'(#(+$$"*&+&*''+"#*$'$*$%&(#*)%$'+!!$!#%*!+*%"'+(!!%"%*'$!)#(!+'()+%&)(%+!(%""+%!&($$#"**&&!!%$)!'"*&)&#&))"+)+#%%&*"#'((#%)+&'(*%)++'&*%
@r1395
NNNNGNTCANTCTTCCTTCCCGTCCTTCNCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGNTTACTGTTGCGCCTGTTAGCGCGGCAACGTCC
+
!!'#'%*)%#!'++$"#!#$$$'&#!("+)#+"'("'!((")#"*)*"&&''!&%$%*)!%$("&)*#+!%*'%&%*$+'&)*'!!'%"''"+("$%))(&"&'%'*#*(&$*"+$'&()&+&+)!+&$#&++'"'%&"'(+*+'+!!#"!+"#"""(
@r1396
CATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTA
+
2>10:#G9?EG3478/'/?7;.*=>GHD:-@!+A!1.-7'<"(%1!G=F1G5%C/FE-,-+?32G6"$9*-1#)&-*"D36E@B7G8H48)E2*8$/6=34"!1G09)>-9$;<>H%7/2)--#?1A"0"?$(:9.7?<>&=*?,+*;7>-/2+C8<<B,6-6-3,7#H'6%F>E77+A;)'>3$+C>
@r1397
CCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGGGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGNTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTAGTTGCGTTTGTTT
+
%-;,G%,#*$&F2@6AD$;=<("B=#<C5'7&.%9+59D9&=++/8A="F6+'458".?=9#18=*5#A;)?.B48@#6F('0"5"0!+?H:A+@A-+1,?E9"')=;:F>4%H673:+123;+<B@2;5:<!D)0&%(B>31,,H"3D52*;+9+24"*%:0$3;9:/!=&&4+2H>,8@>9B2+>)#'8D+=.0(.&!<E9-)C*1-#C,0$,?A1=1B$)C.)'8;)%E.7,*D(*@E/D$,/6&<%/8#6=!93-C*9A65.3*4@:E35.2D#A;:?#1>!?2E899'/8@#?&D##H!D&G%5?G?G1)'E$8"G6%;6$1*9
@r1398
GATGGCGGCGGCGAAAAAGGANTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCANTTCGCCGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAACGATGATACGCTGGAGTACAAACGCNAGCTGGCTGCACCTGGCGACAAGGTTACGTATCAAGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATGCGCACAGNAGCAACGGGCAAAAGGGGCCGCCATAGATGCGAAAAGCCGGGGGCTGACTGACCNACAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCCCTGAATAACGTCATGTCAGAGCAGAAAANGACCTGGGCGGCTGAAGANCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTNAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGANTATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGNGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGANGATTTACGGGAACNGGCGGCAAATAAGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCG
+
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
@r1399
GGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTG
+
#GD1/?..>D1851D4(/*G6DF7F8%!=+!893'0BA'C4'3@:HEDD1-1!FG?6#/.-)4(EFA$"1'9&*2.%&%-(:!GDF!D;#63!+%2?""+$CH#C/92E8004&77)$!=)6D.,+5+(@/!%?5)-76%,3FB%;2'@!D<AF6"@@>%:1B!B
@r1400
AAGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGG
+
0'4<)*)#*=/7<5G4"?=>D#2:F64:8-9*$DBDB-88>9A>(H,2=(E5.3
@r1401
AAATCTTCCGAGTTTGCTNGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCNTATATCACCNCAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTNTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTNAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTNGCTGGAAGAGGTNGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGNACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTGCTCTTGACCGTAGGACTTTC
+
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
@r1402
NGGTGTGNCACTAGTACTCCNGTACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTT
+
&*("(*(%(&"!!"*&$')'!#+$)&'%%+!!#"!!%"$$'$"$#'*&#!'&)!'&#&%!(+**'(&&(*&$*(
@r1403
CCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAAGACCCGTAAAGTGATAATGATTATCATCTACA
+
G,+F3'0=@=G&'6"3@=&G;20.0'B&3($=C)A18;:2#>38$!&02%-/745',8E22,C*':.EH4A5B/G#%<&!!1;0(")=/?+#,:7:/;/G<2AA=4?"<6G7$'3D?9)"#>=-'$;:"G:?.C,5+)F0H@>
@r1404
TGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGC
+
&*+!$%*#!!)(%$&%+%)*$%")$!#!(%(&%(""!)!#''$+!!*$+)("%$##%"(
@r1405
ANTGAGNAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTG
+
"!$))#!+*+"&+"$&'#(&%("&!'''*!"&*%(#)"%(+)'%#(*$*+#%&')"'"'!&"%)!(##%+'$)+(&$*+))&&)
@r1406
TCAAAAGAACAAAAACCAGATTATAGGATATGACATTTGG
+
:3,CGD(=/(B&-G!EG0)DD)>#4C(0$/<7)*G,3HEA
@r1407
NNCCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTACCTGTGCCGTCTTTCAGGACTCCTGAAATCTTNACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTNATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGNGCCACTCCGGCCATGGCGTNCGAACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGNCCTCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCNAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTNTCAGATGACTCGCACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCNTGTCCACCTTCCGCACGGGCCGGAGTG
+
(!+!"**'+**())#+"*'$&&(&*+%+#"&%%$&*$&**'!)"("*"()%("&)"&&#+'#!&!%)%#&*"''%!#+)()#(%+&)$+#!"+((%#'*(!(%*!##!#$($(*$)'!!!($$(&$&$($&&!+(*#++&%)#!%)"!*"%#$%#*%+#)#%##(*)$))'%'&(+"+$+#$#")!&&$)+)*'&*"!('"%#()+'#('*%!%#+*'!(+"""++&**'#$%*#%!&"#)$+'%%'&&&+'%&##$$*($)$%+*&"&(")!&%!#+&&$(&*#*"!$+")#%!$#&%&#!+#+&"'(+"+%"*&##)$')%"$&!!(")&&)"*!'*)$)&$*("%')"%)%+#$!%)*$#%#(+!("&#)$&$&%("*"*)$%")+&'#!!&%!##*$*&)"#!(%*&+#$#&)#$%"&#+&*+!*'(*!%(()&%%!'#&&'!(#("*($#%!'!*)($#"'&(#&)**$)))+)***+&)"&#'*%%%+"+)$*")"!'&&%&#(**''#&+)++"($)"$$"%"***$"&"#"("#%%&)%&!&*$+))!$)$+"&(""$"$")#&#%)*+&%"!'(+&&)+#)#"#+$''+((&*!'*''((*!"#%%$!!&")!"#+"**+$*"!%)'"&'#")!+%'(!&*#+"%(")*#(%%&)&')"("#%!*%!(%'!$''(!&'"$)(!*#&%$%'(($+%$)*++++*%$&!#('+!'+&!(#&&"
@r1408
CTGCCGGTTTGTTTTGAACANTAAACGTCTGTTGAGCACATCCTGTAATAAGNAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGCGTTGAAATTTAATATTGTTAATATTTATTAATGTATGTCAGGTG
+
10@4A.%$2<5"B?*G5B&?">:A1,.".(!21'7!AB5(B2#,!;4117);3-*G(F@!-/;.((=%,7%32EF=8(,H)4GB4F171;%0!F,.8C/,*B!7B0!*7:G8"09D<!2D!)=+.)7&$/1.D>$@-2)G(".H@E1H(8/<$"(..&7D7@EG7('/,6634HG0=$>/<,-3F$A<;4H2F7;;"72(>,#19
@r1409
ATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAAGTCTTCCAGGCCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGANATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCC
+
,,-%AHF?6F0H1*H#:D6=57F;G,$C636!$093,&/G1&)!/07*//+:=)?%8BH?',4C#%2;G#-.26HA%'H@F.6,*.!7'&+>23!9F):7&$B#B/$3>E>'+-:(8?H'(89F=".D7G?0;:%84H&6<2H>#+A@>+G<<.8<H@0%*15?018.;5H44F#-293$"H+!748F"C$#1);&B8#DE7A6#%:A5":=1:E;.CF,E/HB6,36F:+0-1+"><B;E&=<@AE7B.3#@$?D$F265E6/C-D&=*,;$F(4A&CC@<38F4#7;=9:F?D$0+,!,7"-=9D";5(F>E@8944:4"0B<>+H7F;1>
@r1410
CGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTNGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAAATGTATGTNAGGCCAACGTNCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCGCTCCGTGGATCTGATTCGTGTAAAAAATANGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTACTTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTGCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCATACTATGTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTNCTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGNATGTTNATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGNAAAGCGGATGTTGCAGGTTGTTGTTCTGCGGGTTCTGTTCTTCNTTGACATGAGGTTNCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGNAGATCAATTAATACGATACCTGCGTCATAATTGATTAGTTGACGTGGTTTGATGNCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACCGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGG
+
*E#9&*#F13$37(D+*,E-:0BD=A':#;/23=.9CE0$FH3<F!*">H,5..$+GB*+A,*?.&/27A@3'(="<G'>!<D?D,8E"+;%DE8'CD(A@/,#2'7:,,8!B$C$0-034@8>B:3?HE/G;;B70GB@'G&$!4B!;6D2G#!<(G)F>;3&9FB&22#C9>E9.4+8@!)"@@=#($=6F,/E68+<9D9*1)"F2=13G0+;?;$A,33:;F*:B*$2:&'16@0?:BH2FF0@"$-F+2#G+D9=$&#<-0G(21*+;C,&#+?<CG47B%"#$<"$:BED)4!E/)E9)1AA/,)*2A/DB,;"!.916*E)5B(!4,5A:6;8="DDE-@D)8/$+%36<;@&2D01D!6/(1-CB;06+*@$.9':-B??(3%97*5-*58<43HB0,84*30E(3-&(;E'F;G(=*3>:D$>A8=4F#'929&,A)4<6%(A1&HD$-H<G2D-*9?7EH7.-C-:>8BH*?4)??BB7:;B.=$1;GC#:$A@+$?(=@=4C/?2G#%C1<8C(376F7@;)-BH</7@'5*97.,30!5:('&444CA9D8;08-),C&D)H1,F?;/4)/BG5:G22?'F+4F4B5$#F1"0.05&DB97$=!G%#-/0#)0/&.)(+$:=.<>CH("H>+)A:)'#2&+1*33D<%4CGA6@*/=>1%??C)/FE86/6!("'E(6%A*4!918F&951'&%7+$@+7.E&398E(4"3$%"GA1;0:7(2846*8.=<GBF7=4*2E;6/).((74<%)%F+44</7H#3D%%CB,3(<;%-.*+.'C4/986><+@)+"E-25"*?A=$6'5//%:-G/8BF<,B-3$5/(8#%E=$5A4H0A$7A>?A@"#-!$@!%@&E34F:(;"/:;&;9#E>#%7>!4;9#0(<30'$$*/4@;6/7470-,+$?F5GH5,=E:&#D:/!D';+=:G&);<><2""8,#D+;C')<1+8D#;?A9"(E($=9&.'G:%#$@8)A1/3C'6&9HAB%0A.,#('F1<7(AA@;C7&B96H1AG41/3=)7/4'.:6#/?-(%6>(&)'+72<74%"2G.11%9+,?A=D(H'!DA!,@?3H!4<!0+@D/?5:!(/+'B:'9?/(.)8(2!'"<$?(2<!8;E'<@64C
@r1411
GNTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGCAGCAGTTCGGCNGCCAGCAGGTGAGCCGTA
+
&#6,"6#.4$$:8";E3D$>42.G#@C.A6@,$""!5*)='%-((=>3B0<@B/>,9D@"@<CH-17&+8D4
@r1412
TGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGCAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGAT
+
A=&':=@,0DG((='92?G+":<7&4D0$2.6$2&FF/09'E.4/0#+,$/57FB=BHB"F,B-'CC9?:1B1"$/(1>E7!4/.69GG8'9;1-15(-;9<)DF1#B9@0FG6'4$$#BF27&4-#*.8$'63.%+<G$BA.#F/><G4H(E2-5)>*CD9AE(*E.33+9<6,AC73GEF%3'B/@3&B*-6,+;%9D+>8F:;/
@r1413
GGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGANTGGATTTACGGG
+
DD$C(1#8@H4?,9!'3%H4(D>D67+(&,E7A4?(,GD)9.,0)2<2E!<2F!#;-;$B6
@r1414
TTNTCATAAAGCTTTTCTAATTTAACCTTTNTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTTCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTTTATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATNAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTT
+
%%%,;8%A,%97!AG;<'!A:,*3&6D==(+5-=&.</E'-2E+@C87&?0+;@B)*(=8)+D<37E#5*&9FB-9>EA9)4B@:$6.<:)HA?A?0/B2%5%A"0EDA91B150F<0?@C9E2*9,0C0C4&/9*<!*7#7H.*B,+7GB'+G142&7$,@&=/$@/@/1&%B(;,C+#,'12;FB)2?%,.")95/*<7CA="=H',81$"(3=!2>-(13".5?)20GA%F04?-"4#CHBE-*2?$E:BD!6/#4B4?60
@r1415
TTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAG
+
4E5).:!1D1A5)"56(#A?<?68#C#@;94@#7(<02/B4-?$.$,F(/0=,C%=H=6<0?-'*"G&?6+'-A,,=$
@r1416
NACNGNGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGATAATGGTTGCA
+
$&(!%%+'$*)*)+)%)$")((%&!%($%(%&%+)"+%!'())"*$+'+!(%&$(%(#'((+$$#"+*&!(%"()+($+%!+'("*"+#'""'#%%$$!!#(!&+*"*$+"+&)$%(&)(#)"+#+&)))()+!("#"%)""('!*%$+(#++')'&**")%**')$%*('(*$%&#%")**##$)(*)!+!+'$+#!%*
@r1417
CGCACTTTGACGGCGAACAGAGTGGCACGGNGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGCCAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCAGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTNGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTACTTTCAGATAACCGCCACGCCGCATNTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGNGTGAACACCGTTGGCAANTCGGCATTCGTGGNGGCCGTCGGTCGGGCGAGCGATGATGTGNAAGGTTACCTGGATTTTTTCA
+
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
@r1418
TGCCACCGGCCATTTTTCAGTTGCTGAATAAAGGCGCCGGGAATACGACGGTTACCCACCACAATCACGCTGCCGCNTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCNGCGCGAAAGGACAACCCGCAGCTTGATTACAGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTNTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGANCTGCATCAACTTAAAGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAANTAAAAGTGATGAAGACTGAACATCCCGCGTTCTTCCCNCCGAAGAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTT
+
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
@r1419
GGAGGTGGACAAGGGCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCAGGGCTGANGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGNGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGNGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGNATATTGGTCGTCCTGATACCGCGCAGGANATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCTGACGANATCTGGAATCTGCGCAAGGATGATTATNTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGNCCGAANGANGGCTNAGCAGCACACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCNAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGA
+
(+!*)+)*)%'(!%+$&$'"!%$'*#''#&%&(**%(!(#''%((+%##&)#'""""')$'($$(()%&"!(+)%#&%"("'#$((&'&+!&#'+$)$+'')))!+%%'#")""%"$&$'+&*&%*"*#&$)'!'*'&+)!*$"''!&)"#!%"%''%*+&'&'%)((+!$+*("#$$'#+"%(%(!%*((*&$("+($%$%%*&%%&'&$""())('"'#)"!#&""$)+'#$!"(#"")'"$!#%*#%&$)*'*+)%$$&!#)+")*!)'#!*)"+"*%+)%'&(*'&!"$$(&*&*%&')'"$#)!&*+#*'"(!)+!(#%'+#)"")$'#*!'%+"#"("$)+#*%!$)**(+(++$%'*"%+*!"%('&(%$(!%($&"!%%%#$$"&+)+"$"%()**)*"%$&#&"&&"%&#)%"%%&*!$"#)()$''''&%!*'*&!%(#!#&***('%#+$&**(#%&+!#*!'"&"(*")$%%(#'&'(!**)$")&#*''*'!+*%*$$%&""*%"!)+"&&$$")%"&!$+!!$##%)$&(&)*($!&#*"$+$&*($++!##$(#"&*)*)*)"("+$#$
@r1420
ACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCNTTCGCCAAAAAGCCCGATGATGAGCGACNCANCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGACT
+
C@5<2<2*-F7>AB'-0%02%>9@$)72GE:EH6>C#?,.D8,46(E'"!?(7$=$62,8G"B(?7#?$D//)58AE="(5(?<5$//H36G,<;0;)G6>45$*4>7%?;#*)"#>GE+<=6/3"B@:977?-<6+F:!>30&1)&*(./%DA!:H@5@:1.<('$*%3#7B@-&6>+34G29#:HC&*H8/$D05356C%#%?')36"EB%@H"";;+!D+:>*>2*"@A&050';G.7D$;0#A;@)$BE%>*1%#4#<#HB-A%%"+3/A>H$":1%!B2G=@<E2A-4$?C7%HE1(737=8FC8DH"3:5202=
@r1421
CCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTG
+
/0G2#:5A230"!?+2'CB1?*5#9=;72=?4<+'!%9&4-0?D53F9F-98-;1H?$
@r1422
NAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCCCCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGG
+
#(+*+!$)**$###$!""*))$#$#"%&*!&"'+#)("!#"!%&!%""+&+"*+)*"""$!"++%&#$%+)"%)!#))(!%!#*%'#$)%!+&**"+&+'&&%"*&++$&)%'#*+"(&)%'!*($$())#"$!"''+*)'"%(+!&+
@r1423
CGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCC
+
C!%D#.@(!<=A%"+E69<+G'9!0C1))7;+4&C&99"G;9D"C/829,-053>(>98?3AD.BB)E;#-.BH;
@r1424
TCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCANGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAA
+
/>7@%99$&-49:&#,;D8,"?"F$>;AH$2$)F5%%27&1&%-:3$FA5.9?!G=-*003/6$/,<95+EGHA0>7:/AA<1--@1AEE(42G3(H**F#2<1.#3-6:;5-&C/2"-'9D=$1&G?&ED9*+93>$%6>417/$2:2@>%3G.&=$!!5G-5@9>4A:.C,,,E:/H22$70CA+AB)@H.8@D/C%,>B(BE-C')!+?,A->A$D,D>*!%)':+B%G(+D#.<C?04(%1'D4DF(-?!'C
@r1425
CNTCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTNCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAANCTCACCATTACCGGATACAACCGGAATGTTGACCTTNCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTNGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTNCTCTGCCCTTT
+
'!$>7&)4*3#%C'9?!#E3/8+><A-FG..8A<D?4H9:()C26921&9(F/19C@7+/'#B?74$-!$A;EEC#1D4A6<<E8)8'CB(/%=3+##<%+@+D1)F!>7-)$=%:.G.1!"80"8*H?7==,4:=.7DC@B=;='"GA*!"GG*@E3@&A.7A40<!0>=,.$%<=*;'/4"ECBH/=+0&/C=A9%"3>>>6/6@B>@*9#643$CG60"B+;B05+*#0!H5A@C+#@)7-5A:0D6;#CF)>@9<G?8;9(F8#2:@$!(/2:%H<(3$,8;83$F4/6,#<"%C#BA"-683="F&+0A"A(B02H<#3D?<)<0$A-(@#G/%?'.3",6,H?>F9C,+90/B39CBH"7D"#0&,"2/1<&H7%&44%D153#6):D5%-)$+$+D(E2/*3C$*A16'++H<<=)A7:F:9E(0&,.;/*H2-F6.H:5(49A03,618G#0).*(
@r1426
CNNNNGAGGATNGNNATAAAGCGATGAAACATACTGAACTCCGTGCAGCC
+
'$*%$#))%)'"&)!'**&&%#+*&&+%!'"(#+"#&%'()%#"!(##*#
@r1427
CTTCAGGTAATTGGAATNGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATANTTAGAGAAAACCAAGAAAAAAAACCGACTTTAGAAAT
+
A'4DC!,3!7>@:81.06+<G7"7"EAG)H'("2A@$&00:+7@16,E-BG>E462<659&&-@30*,(*?G4@+H9D&:>F30'G>1@)>+38:
@r1428
CAGACCACGCTGATGCCCAGCGCCTGTNTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAANAATAC
+
/,)H*>@+!CHAD19=&9#:/H:'.</2@(;<"5H)?'?>H(1:,')HH>#1->A9D+.G"=0G88",2?1.-:?""$83)9"6+:B$A7E!*68G+627;D00**!4434(E@AB..)BG=<:1:B738"C53E*.*A:AA,<>?#)5*1&D-
@r1429
CCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGNCGGAGATACCAGCTTCACGCTNGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTNATCACCCGCACGGTGAANGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACNGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCANAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGATGCAATTTCTCATGCTGAAAACNTGGTGTACCGGCTGTCTGGTATNTATGAGTTTGTGGTGAATAATGCCCCTGNACAGACAGAGGACGCTGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTNTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGANGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCATCCCCGGATGTNGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGANGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAANACAGCGGCAGTCGTTGAACAGTCGTTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCNATGCGTATGCTGCCTGCACAGTTCACNGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGNGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTA
+
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
@r1430
GTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCC
+
>8)$&"3>B"?E75H594&0-&)6(C6(6)@2$338?A20.3A.->27E)77G*/4,;-.H1"E%<B>,HD@3&:!0%/789!9$8G0B;C5($?0#02!(?%7@',G%@C',(*?5#BGE@><&<D&,=
@r1431
TGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTG
+
!7D@,;("#?1F26%C:)$A1<$)F9@61*-(9*">H'/63>;@D9
@r1432
GGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCNGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTTACGCGTCGATAACATCTNCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTT
+
.<A11='35280,000$:&96C**6*56)3'/(-DG27,:(9+(#5.,91<=!276'(37H9(EG-ECC7*B'H$@&%F=?BG73G*G4:0:E8+?C:#429D1H*#9,E=+3!344-32$E>>#0*5"%+)5'4.<1+09?6=A*)F%6#92?EC/C9H,."7+?/(@5;,%..E<!8;"=:.2925F(<:AE(B70F$-A0=028B:C3B<>.+,CGGD2*6E';7CAC+!'>'#>;/877(56D3A>&@F1)E8G,97@C:1*?<-'/"-(HF##>"D>)3->;3&C8(,#1A+@86G6$C80!#,?$@4E=HD+>1@F0)H-&-A=H*@!&=E4(&;F$H>CA>.5!F$-<E>H#'*(#F6>@!-#92:,#H9(>,/?C736+9)E;;+;$&G-5#+%1A::<(<F>1/"&"8!4:%!?6?C/B:/A,F;6=8>18
@r1433
ACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTT
+
@%>8&?11551C-.%&E/:H<2%>@2.9E9&42$&%,=-%'EF,+5@(B#
@r1434
NGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCA
+
"+*&"*%+*"#'$'*+"()(++#%'$%"'"!&$"+('+"'++"('!)#)+%*(!$)(($"#!#&!"!$'%(#'%&*)+)")(#$"+&)&&
@r1435
ATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTNATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGNTNGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTACCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTNCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTNTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAG
+
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
@r1436
NNTNTNANNCCCNANTTGACNNCNNGTNTNNNNTTNTCNNAGNNTGNTTTANGNNNCCANGTGNTNGNNTNNAANNANNTACCANCNNNNGGNCNACGGTNNGCNNNNTCTGAGNNGNGAAAATTNNNGAGGTGACNGGTCCNGNCGNGACGNNANTGGGNNTNNANNNACNNGCGTNCCCCTNNNNCNANNTTNNNNNNNNNCNCNCNNCCNGTATNACCTCNNAGCNNGNCNNATNCNGAGNNCGNNNNTNTGNATNGGGCTCGNTNNAGTNNTNGNAANNAANNGNNCANCAGATTNATATNGNCNGNCNCNNNNNTNATNATANCNGCNTGTGNCTAGTNTGCNNNANAANTNAAANCNANANNGCACGGNANNGTNNANNAANGNNGNCNTCNNNTNNGGGNNGGNANGCTNNNNAGATNNNNCCNNNCNNTNNANCTGAATNTNNNNNTNNTNAGTANNTAANCNNNNTNGCCCNNATNNGGGGGATTCNTCTNCNNANAGNTAGNNNCNNACATNNNGCNC
+
!"$"!$!"!!#!"#""#"#$$#$$"""$"#!!!#$!##$"!$#!#"$!####!!$#$$#####$$#"$###!!!"!$##$!$##"$$$"!$"!##$""$"!!$$$!#$!"#$#$##$#$$#"$##""!$$$!##$##"!"!!##!#"$"$"##"$"!#"#!"$$$###!!"!!!#"$#"##"!$"$!!!#!"!#!!!#!$$""$"$#$"!$$#!##$####$#!!"#$"#$$$!"!"#$""$!!#!"#$##$"!!"!"!##$$"#$#$""#$#$!""$!!""!#!""!""$$#"$$$!$"!#!#"#"!"$$!$#!$#!##$"####$$!!!""$$!$$!#!#$!"##"!"$"!"!$"###!#!$##!#"!#$!$!""$"##!"!"""##!!"$""#$#$!$!!!"""!$"!"$#!""#"#"$#!"$"!$$$$!$!!#!###"#"$$!$!!!!""!#$#"##$!#$##!"#"!$$""#!"#!$$"##!#$"!"#"#"""$!$!#""""$!##!"$#""$$#$"#"""!"
@r1437
NNACNNNAANNCCNCCNNTNCNCTNCGAGTTGNNNNATTNCNAGACNCANCNCCNTGTANTGNNTGCNNTNNTCNNNNCNANNTNNCNNCNTTGGNGNNCNNNNNATNNNACGTNNNNTNNGNNNNTNNNNTACAGGTACAANCNNNNNNANNNNNAGANNNNNTATAAGGTGTNNNGNTGGANANGAANTCGNNNAGTTCGNNGNGNNTNNGANGTGNGCGGNGNANNCNNNNNAGGTNNAGNCCACTGNNNGNANCNNGNNNGNNNNTTCNANNCNTNCGGCCNTNGAANCGANNNANANNNTGAGTGCNGAANTCTN
+
"""$!"!$#!!##!!"$!$"$$$#$""$!$#!$#"""#"$#$"$!$$##!$"!"#$$"$!#"""##$!!!!"$!#!!#$#$"##!#$!!$#$!"#!"!"$#$#!!$$#!$!"$!"$#"##$""!!!"!!!!$"$$!##$$$#!"!!#!!#$$!#$##$$!"!"#!#$$#""$$"!""""###""##$#$!"!#"!"!#$#""##!""!!#!$$"#$""#$!#"!$$$!"$!"!##$$#$!!"!!"$#!#!$$#""!$$!$$#""!""!$$#"""#"!$!#$""$"!$$##"""$$!!#$""#!!#"!!##$""##!"#!"
@r1438
GGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCNGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACNTCCTTCGCCGTCACCGCCTTACCGATAC
+
2?*#GBD6E67F:C7>8.2+C&DH;77<?H>=+/3&E!6#/F;BD$2(@%E5&#'4G*69@:+9$@*&2A;.;>'HA+:G7C#>D3=;%A)*261C,+(/'.%%AH8'>/:2/B")@4=6)1C#/?)19=8,;B6H)C>&<,%/:@!&CD;F@$C,16BE#,.&8>!D,F:5.(,&=&FE,"2+2G=)6"C.=BH/5$2)).4FE7FGH8F"7.44!#G>EA?75**G&A>>?$$H?+1
@r1439
NTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCNCATCGATCCCGGTACGCTGCAGGATAATGTCNGGTGTCATGNTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGANCGGCAATAAGTCG
+
#<>!8@;;!$0E%@G1/3(%=$4(C=/%>3<."E%?,("-892)4G7CFC.>@!%2&*>-/%8=>-1G=);?3$+"F1$A(1F)(BCB!H*D$*6+&>.CH(:.D'F@8%!?0#&;+<>;@$>A&,*6934B&+E6*HA:?,5:8)3*9E)+-!99/&C6,=6")H5CB%!H)H+7A@$2!E+2CGFF1CH,7@A;)F87=#9747FH,1@-<-)'4(A<*<CH;"DF8&.=F$G
@r1440
ACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAGAG
+
E",$0*6E$!6$*;:.,'-:?.(0@8-!085B!"3E38-F!&)'@'HG75(3@$GD3
@r1441
GCAATCGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCNCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTG
+
A4G33392A'>/E1$283.=>FGE#@6E(-2FE"D*.E5"8#,+)6+>5!#E6F)2:5?<BDG&'6951B?>5,1,76'!#*-)D/+1-<0>?(G9CFDH9CH=G+;4?(F(B"!8+B9B(C7,3A+3&(%31C.8D;0%'E@9-==DHBFF2?#8?B@A'B.65:4
@r1442
TGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCATTCTGGCTGAGTTCGNGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGNCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCTGGCTTTTTGGCGACTGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGTTTTCCGCAGAACACNGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTNACTGCTNGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACG
+
1=?.4'.E16986(#@+@A<.%5:8=@""HF&'%;E8A@,&$$54%>B.$&'8+,;1E7%C,6DG=,$!!>+;E(D!:&%*6,';&5AB+C!5A;5&".<3+%8GB59$E(<;E74,.'4E);>96A+G3/B%D%/D8E<HE0D<%<#"C-E%%G2@(%/):H=3%9)7G'#H83"6?)!D1)?D$=<69%*)"=C/*1*7C'>28,=<+!3FFEGG;8C81!'0GG#FH(%).7,:!;1#4=5+5:<8F+-1-@CE?->/E0;"/?'"/GD1H$2&=8/)879->GC$5""9G#BA?(</FEA7A@1*-4H+/G@5'&6;7$2+%0&$F0B@-/&)<;5*%6.06$/?9)H#$#D!)!+/7F6)H>E2
@r1443
CCTGTACACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGNCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGNAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTG
+
@.DE6.0>.-'%A8@7'43A9#EC>F7F$'G$;+:A?C1#..,8>#&CB(":-7CB5B>!E?A%G1/&'7FB8B"9/EG>5G!907;//5E1+2H*.3?-$F/5!'>A5GEA,?+1E),<+-8?<4D9+(HHE"0BE4'6#/!=6$@<D&G;?589%D&$33>/*;14DA),6%?(/E4!H@!5=2:GE@;4++"-A+7?$<@1(16#,:=@:,8*<$1-CHH:$@7;60D-+8@A3<8G.
@r1444
CCGGTTTAAACGTTCCGTCCCAGATACCGCTGAATTGCCGCGTCTGCGGGTTATNGTTCGACGGCACCTGCAGAATACGCCCGCGC
+
H35E$A2>#;>.G*&4:6>*'0"2).$!4+9!,6=&;"8".9#B88E6+C259=H+,"(5$1!9#+D8!2?,!E'DF1$&.<86(D
@r1445
CTGAACTCCGTGCAGCCGTANTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGCCGAAGAGCTGGACAGCGATNCATGGCACGGAGCTGCACATCG
+
&<%-%6=@?'9;B6'5=)13%0"=#2?F2E0*4!3=?1(BH?G$0/<2=%8/"@0;F0@A,!$''&0H#C6/BH4+79DC5G***B<-?E.41=?3$CD>@*739EH52H.04E+HB-<+<+.64/5!.=A#?%#D01F1'+/.&FF):;6,-$-8*<EE>%8"*".!"C/%55&3%F<-
@r1446
GAACATCAACGACTGCTACGACCACTGGATGATNTGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGNAAGAACACCAAGCCGCCTGATGGCGGTTTTTTNTTGCGTGTAATTGCGGAGACTTTGCGATNTACTTGACACTTCAGGAGTGGAA
+
0/<(3(0/-+:GAE:@6%@-"0E0&6)C2?#E?D)8*B(4,"(9(CD");7F2@&/<=547:($0*;A:+8)EC("&!!F!8AF-D#E3E(*>:*@0;?8B6H:0F/%:5(D;(!85/<B<.+,/.+&!<=:(9E*%5%!F/6FD33G3H<2AG8.D$(/1$;36.C'A1D
@r1447
TGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGAGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTCACGGCGATGGCTCGCCAGTTCCATAACGTGTCNGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGNGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCNCNTGAAAGAGA
+
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
@r1448
GCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGNTTTATCTCAATATTATATGGATCATAGCTGGCAAC
+
@69=(<=/3?9/,%/4<#7%./45B5G68,E*C.0B*9,755'60<B&G*HE&:?B84&@H+0*?>7(:F8CF<D,B"D@B=4F;*6:*:G",67
@r1449
CCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGANAAAGGAAACGANAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAANAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTNGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCAT
+
G-"8&*B0C+,6EGBG07C;F6>(C'!*-!/;E+%,(;E5D<50,@)@(4,70E$42!)D/5,1%EF)FE!:%8+H.52,AAH-80#3>(GE@,HH4*'<&8H5..D$5BH#61F5F$:9=/?$&A/63.E8*(.+:;>/0*##*?<4)30>0(7F6/:00)66-6.8%+@!590FH96'/4#=D)$,/-:E$(?2072HB/)!?:>=2?&2*D4/9-.+9&)H6.7F+3)5HD71'/?@+:8=E4.$,A"A++,G>2B'C!?2+HFH-5D.(+G)C68A)+*F(/F*;>:;C3?1>CC);?,&.<$18)D2/AC))6)<27#0!-=6=!C3C'H3#"%F+(.?7$0#<$E&69FF=#"&$C%4(&)<GGG!?#2C>#32,!(&*F$D%3-%=@9.*D8E78B&>)+#(!C"*'G;)A*.>C)'56-+3*:()':,#,G)==!(8)+F(,@:4/D?'BH+E
@r1450
TNACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCNTGACNGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACA
+
%(?(2D?5C;*?="D*1DE!1/BC2"8<<?*.:#G0##C+@"B0@'GF2@,G.EHADAB5G!%3?#1"9$',,(,F3CD<G52E-@25E+A1,>C:0!3@.H4,G!HG4=.&0>-$$=-)>7.')2G,#12832.A#'5CED@0!"41*
@r1451
CACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGGCACACCACGGTATTTCCCCGATACCTTGTNTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTNGTGNTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGNTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACNAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGNTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACNGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATAGCCAACTACCNAAATATTTCGGATTTGCTGCCATCAATTTT
+
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
@r1452
GGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGGGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGTGCGCCGCCACCAACAGCCCCGC
+
582:/E9$A84:;F!4=-6A=/*:*,.=@75(D<B*A;H?:2'E24#:!6>0>5202+/!3+01B969$@8:.=04",$)#A?3"*<#G,3;19D$+2G()G)"!2$A>.-/DB9>"%$3=*635E1>'29:&%3""*,*5375"">)1E301<17B>)>%$<%E:<
@r1453
ANGGGGATGGCGCAATCACAAGCCGGATTCGGTATGNCTGCATTCTGCGGTAAGCACGAACTCCGCCAGAACGACAAACAAAAGGCTATCAACTATCNGATGCAATTTGCACACAAGGTATGGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAANGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATNGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGNGTCNGCCATTCAANGATGCCAGCAAGCGCAGCNTATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTNGTCA
+
)"?01*6F$<3?5::.C,2C&96E:8E(F)D8)4245D!<.-%#F+0*9!%:#/?A$H8@7=4B>("&?($2,6;>#?#1)?*#A..<<$G$)'H/+$.D412550'H@(/>9&9H).%0-C?93E!AAD=*/$GF64&;19H9==?$,A<G+7G=#.A?B4A%1-D@'#H%$F!;GA<1H88=G-B%F0E#A8+E1>&B>@G+6E@0&6.?"C#DE;)/6!(/)@3#*$4:E39=",4!;2BC+:<F1.(&?6,B*8H*8$$?,7#&;.-FC741+(C-*E#-/B7%EH2C/'=98?<:A+15G'-54'DC,AD-H<+.!EF0E4&-:!54AG3/&:83=8$B,.EA0>/7).<@4?;(DE%<$GB&E'B=@927%DDA8=50()3GA.7,D9)%+64?G@@#D((02!+/%+<5EF+(
@r1454
GAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCCGTTAGCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGG
+
2:$7@>H<34EE++%69D@FD39D:,H+1)@F5G((3<=-#<%0@&,G-?<&3A)@3C%F;BA29..&+8!D.D2'!?)9*&A><,&!793-1E0:2B,+;,%H96*;FA2B/+@9(+#B9&45&/-)D&@HE3*@$>B,+3/+:.-D(@9"$+*C#%&-:00/D;:51&,0!B.G"($'%7H!H4C4
@r1455
CTGTTTCGGCTTTTTCAGCGTCGCTTCNTAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTCCAGTGCCTTGTTCAGTTCT
+
@337<0BA/4F9?%EF8!"-%)4:'>*'6D9E<*9?+D:A2!1(A*8H,$;D#DA:73-9$,/(B!>%(+#+;4'553.50,D'475-=4F-?2$:)+'91.FE&*=5"
@r1456
TGCTACCACCATGAATAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAAT
+
G0"6E$'A</!5F/.EC*$<C-H/")'">"B;,0'G:A)84A9D*D2&<5<#&+CD!47/"#-6+7!(4G<7A2<%B9+3C82DC,F9
@r1457
AGTAACAGGCTCNGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGNCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGATAAGCACTTCCTGCTCAATCTGTTTAACGGCTTNATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACANTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGNAGCAACGNCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGATACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATNGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCNTTAACTTTTGCCAGACGCGACC
+
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
@r1458
CGCTTGGTCAGATCTGCGCCCNAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTNCGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTNGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGT
+
AE.;1<H@83B2%D>'<5?1G$9F.,7-#24"+8C1$#)11.?9<""=&1D=+.:138)4:;DG0C*%>5G!#01D$<)10'(AF/!C"8-4CE$13/>$+!-1A0&'@!D=%91-65"B36=9-2.+C5(B$FB&AD4D&3>)1>D=*2%EAH>9;F')1&E;>173@@?=/>"!!!F">5A(2-)9)GF2&B-4<"B7ACC%*:F.!&9
@r1459
GCGCAGAAGCGGCATCAGCAAAGGCGACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGANAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGANGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCNCCTCTGCCGCGGCAGNCGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGA
+
/E#2'7D#4AF>=+5H=4$3-*D038G,C,39;1C4'A.@04'!?F*4!4B8=%%7@>56DF?$D6866'@2F;*$,B)07?:%'0;*D/8D&':H=C$G7@B52+&A>"2$D0*H?85838.G8&8$/(8C"76%:$/?DG)*C+B,;G!9"(9&=:=?3GH0-6&60H&/'">BH>,@:.B0G>(=97:F05=@D-@00$/5@+$F-7;3<.E>:D&52>)36:688H4&2/@@4-(!B,2;GC%*2.(9(0-D&#::'@C-E)61><#$+?EH""=0'*,9!$.=G$*(3"+)73F4E+)1((3D.=9('E)+A'ED1&EG'-5"A+F.A!.>E*F!HD4DG!0*,9(E@:@%D8)A&65B#!B68@B+?H9&7,;6-:4)>:/'#672H+EED<H8B:>9.*:-&<0DB21$DAH&!#A@E'A(E0C,@@15#7E&
@r1460
AATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAA
+
C#"'5B?G"D<.+''14D)&&-"*-6&0.+,A3<=#<45-9*BF*/@/(BD7/B*#4&>$HC;#7,2979910<1H(H@#;&$?67(&;05H'*$1E(+??4H'G7*+.
@r1461
NATGGACGCAANCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGNTACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCAACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGNGATCCTCAACTGTGNGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGG
+
%)@:7(9A=.00##7"8>B7E7'&$*378/A9$3@42&947!$GA*E61!,A8C-<0C9)/17+<G<#;9"$<1)&$,>5'&+"<658&B?&3,H>-8.B6AEE/G-D/>:08D*(<:<?0G48FH$A$E+$=<@)2#%7==:G>&(0+A#2C%AGH5/4;!D"12-5%3!9"0&B$$/'4'/$F@!G'4A,>+DE;/%A,7F:'5!(7;0H*D6/:A:.E0/E60&,"":B/.G8$#<#:.,#4680"EB$+D=&!2H/7&F"-F,/$<914,!<!">$7-&$B5:(=C(8,-0@(F$-B282(AEB?"?@7"1+A7.(8?F&B?<$*:563.6=A(9$?/9C#=(*5.<#7%?A8F7?$3??8GF:@=@"B:0?;9-5C5,:?*1=!G9H>>%"0(H<#,3H8F/F8-G!,!5(<"7*6"')59((7@-G8#-G,@5,CA?*?A*$#@?'8:"<B$
@r1462
CTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAG
+
C)(3?0545+H.!758A/'8-!BD%,%!*$5E&;8)B5910'F(/*F)5*-02-+<0CG/
@r1463
CGNTCCGGATATGNATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTNAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGNGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCCGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAANCNGTAGGCGATCTGGTCGTTGATTTGAGCCTGGATGCGGCCAGATTTGACGAGCANATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAANAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGNCAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCNGGTGAAGGACGCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGNTCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGCGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCANCTCACTGGTTATGGCNGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGNCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGNCCAGACCCGCCTCCTGAGAGAGAACATGGGCACGCNGGAGANCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCTATGTGGGATGCGGTGNTNGATATTGGTCGTCCTGATACCGCG
+
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
@r1464
ACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCC
+
.47'@E%3?<:?0);>B0F8@<'+G)H3308,E,+3'<3<DC<#<)-&5$0$.A.C;(8#?'7&5C&8"$(("85HF>6G(.?BG@$2B=C4C%H'C%2?HA+DF8(=%C86!4F8@.4)C+3.E
@r1465
ATTGAAATCAAATAATGATTTTATTTTGACTGATAGTNACCTGTTCGTNGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAAC
+
F7!C/1%(2$5E&6?G@)$@!)>$C7<-D(!,+$C1,&5D99"5B5.AC,0.;2BE62$31$(F#-C5>01)CA&!<580+HHE1G+8
@r1466
TAATTCTTATTCCTTCGCTACCATNCATTGGAGGCCATCCTTCCATTATTCCAGTCGAACTCNCACACAACACCATATGCATTTAAGTCNCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGT
+
;CD)0A0*!;H5539(+5$/C=5#=,A$1>$;C!7(H.G1%@/3*)78"E-A3#?5,-:2*=6$-;#<C**@-*+@?";H#8'3B,<1D?'(H5*/=1+#-%7*<G');&1H6,C9/=?343':8H:++B!H72.A@+==G5%9(A(+D@>)42-&>#"#6*,6@/*+=C$95CGH./?:BC1@>GE<%H7#G/DE-.95#3A"'
@r1467
TTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTNTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAACCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAANGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCNGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGT
+
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
@r1468
AACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCATTTATTCGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTTCCAAAACNAATGACAAGAGTCTGGTTCAGAAGATAAATCG
+
*1'$35F).$71F+2D4<2'=D>9<30BH/)?0GHF/FC#&A>6>('4:!HE0!=G.=@91$;15'0>2.687":BE(D"2#,@2'551@1$H66:1(&/0B$2-$@H:.=2=$;)/(?E4AE#;&2@$:'(8=#@,:?6A!=2E+"C!$4?=B6;;+;"HA+7$"8G+$&1&B>31$!5'F23A4&@2;>;!8.,-$35'+(B%9ADG)!3FF<5#FB4@@+4G2@ECA?!%F?C
@r1469
GTTCTGANCANATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGANGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAA
+
83.=C9@1/!D)!9=G?-@=*+<)83+<%6C%?:9!#53!?)@(/*E"-);'81@92D<7DH#GGF$H44B:3H5:)!$30".#F>&5&DF.34C95=!?;(14?27,(=9G62<%G!B?9/)':)>6H*4&%56&#%:$7#/1$:?"H<8>F3.E(+*0H%"(B?3776@F$,<F;/99HF6()A(A4(83&.@@*H@?:*/*F97<-(C8F
@r1470
CTCCNCGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGN
+
2@@?&?D"7,:@4'E!A(+&"33G$G:B737(7%D:.=@+F:A)A,)9@G@6:G0,>16/5&7;#*@/?<=2B8";9
@r1471
ATATTTGGGTAGTTGGCGATCTGCANGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGANCGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCANAGCGTGGAAACGTTANTCACTGGCTGCTTAATGGCGGTGGCTGGTNCTNTAATCTCGATTACGAAAAAGAAATTNTGGCTAANGCTCTTGCCCATNAAGCAGATGAACTTCCGTTAATCATNGAACTNGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATTTGGTCATACGCCAGNAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCAGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAGGCGTAGCTAAATTGCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCCGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATGTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCG
+
+*'E'06E%',/(=00DA<?<@!.)'(B$A+B$;6C'..?A4)"1*/0&3%==*7*A9&7;DA6$37FH':!6H'?6,&DFC75?<#A@F!:94FH':,618;8#$C4">?AB7&9?"#3EF8="A99(5:#?F&2@((*=E06&,'>9%+BEA%$=7@@(7C"8-F'>A5(.<8;(A:/CA/='5+65G;;#*%3.235?<"3;$D&G>"@!(-+23.$+31>="4/5=C!(6"?8;E3D)?4C*7*0>.B'3H3(D!42#'9*>%G?,@@'7A%@.'A0F5"D;-8H,*+ECG"'5E*.:+5/?.9E,*)@0<D!4,1+D>?*;)9*)-()%D8.@+&#1-#C!#=%!2F/)(G(%=4(#E:&7#(9HEGCB@3G>@D,%/=/0/,-600<FD2>,%5E&<,6"3C,%!#1$:D;"AF->0!-=*=&!)4*96GA9%7(H?/:/@<=1+G;7#9.33/4",?)-<*1$(H@%'4?D5(E:AH):<,)28E*-FC?7+)E-3D'B;%A5G63$E0)@%?CD57&B&(#?E5#6!EH>3)0E422?H9);!62/B;,?!1%'192&?-;0",2>(&C(H<0%+6)(F11&7B+,.*40=HC"@!;(&9!G5<??>4B09E<%&"57;>%/@?;+?7)B)+7F@BD*1-27D.8=&);06'6%EA!!>)-C>B,%/(1=@8301@'/2(27>7:)%/@G#D$1AE+":%!H5F-%H!6AD&+.4G=&??'?G@"?&3=!!/)G7033@>=?79!3"06*?6=4@&#%C#6BEAB<2C<@9%@H*4:".?#8HG=<3C#4?),+2!#<!-43B;#%813.=D*269%(".D*3/G!H)!H+/A84(!D/A998H20-/AF/.&6HB!6-*3*E1"EF2H(84H5!:,*04;GFB'9065,<B5?>'H!;<:19'+<6+A8
@r1472
NTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAANCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAAC
+
$<0<;43G5(-0@H2/?;5<9,-9DA<<5H89(5)?0D-,9G=%!'?@D;",(-249)E@5E"AD4:%F(FD4)B'9(:<37D@8!8)'?@D667-8%),$2;.&@+"B/"C?H76CDH:+9($*=.6HD(,*/0?93$?(E@##?!0E0A"!*)F0A'@.<'+(0/04DFB'/25A-$0#E.6/B>F<3D;$-47#<%A(1&-6*AE5=7H*"G?%/*28(9:7,@!*<:+"8"84*<)7EADG1603C?2<%6HC=06*6?9/00/H5)2(@1/DF*))>9B2$8D!)9*6#!1C4<1(725#!%&67%G/!D>-6,D&0(57<6?2"@/%).&!DEH$4A3+;E!!:B4HD3@/A1G,/2*&,(69,
@r1473
TGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCTTGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGC
+
?/"%72F(')/846CB6?B#&*FH-21EH:C:9#C:#A%G0'36H?A',4!59!,B4+G.7CC22B;4BDH"++FA0H0?,.:E-F15C(G;32%!012.&H*#%F;<>?"A#!&E
@r1474
CGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCCCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCNTGCAGGTTNACGGTTTTCCACCATCGCACGCCNGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGGTGATGCCCGGCCGGAGGTGNTGCGTCGTCTTGAACTGATGGGGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGATGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAA
+
'/@F/$#F!(<$,/A+D9253,026+3:-,?,4+!7/<68HG2E19CC5/+:<998*4*D5"E!,)216CAD?<1'&-?;/@888/6C*68",@"4%%B!A1ED8B/(#%9#=/E;9&50?E2'C96#17>>>;5/3G@2.FEA@6D4:C1"7G.>4&#58+<"+E@@F(FC/7-A&E?+FE(9:)D!>;G:3'($,*F;&5(C)FH6;5*"1:+9D#4:A5-=/B:+'!.E!@H/,*'<=1,<=*E+:?(%''/.B?A,&G7>5+$*=8!0:;!H:E/1,"G>(29&A=9$2G770E2#H58414:<91#87GB!7;'C,%')3%".7-/-0'/6G?6,)"5=#&9>*?$/<7)(<DG#0*-:4,;G->7#E=*1/;2:*3;F<&D,3/,5/FG:8><
@r1475
GTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAG
+
A3!A%@2#0'E(&7C2&?,@D4&<%2.:H-3D?.@<+?(/4+5>0?D7+9>2/C-HH77<1E34-7?D'4F:E30,C=F.3+H460""B'1F9$.1*/?4#GD1()B</-*<&@9<C0%GB.)A<D,620<+4=8)@+@)=!3$E&D6+A@@B..($6A3G.?-!8-7H4;7@<=%0<6A:;0C0B1/("--'3C4*)'<68(G*@(1EF+)>GGA(40->H8)?A71%2#$48=?(-HFD.(=?<@C>21
@r1476
AAAACAATGCCCCCCTGCAAAAAATTAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGGGCACATCAGCAGGAC
+
!.4&%*=,,H8D2*"'5+B/5%7('?*B5/:+(F74C")*#+"C3A@))E0,$>"E>FC$:"GG/65/7)A/";;7%5=-D6/1HD%:C!A;C?1>)<C;?:A@3#?/.2$&(2'-7?B55&;+0<>"&;
@r1477
TCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGA
+
@"?B(E5#>4'A1;C$>%6*"=F-D)F@B"8*04D;;,3$7F/7&%D-)D9%:B$=)0*65F
@r1478
TCCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCANGACCGGTGAAGCCTTCGATCCGGTTGA
+
*"(+#&&"$#++!+"&+))%$&#'($('(&$%&#''!((&*#)$*')!"*!)"%+&$&'*""$$*)"*)"(((%!*&*$)%''&+%"$#)''&)!&%+#*#$**$**&")''+$#
@r1479
TCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCG
+
'>=45(FC-1)?88%<F$(B.E2,+<G)A99.A$=D#&810*6*:F(!!D<;)2!BBC(!A:)4&@4&'C<@><+?!+E*)/&C&45,G54%H@(-3!9(22&AE(*51!A<E++0"<(=!BF=%<,<4;&'.%>34%='<>04H>($/%5+&,7?&!E73G1F2@.?,0D.04'5FE#+4(6B<3E#,H2)DE6.6.4<263)0<'8?E7-@E<BG'3*
@r1480
NGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCNGTGGTGGCTGNTCTGCC
+
!)#+!&***%+&*%"#+)+&'!&'(##%&!$#*)($&$)!&'!)&%$&%!)"'")')%&'&))%!%$!#($&)##')#+%!+##&(+&"&+%%
@r1481
CTTTGACATTNATTTCAAAACCNCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACC
+
*'$)"!#&&&"&"+$&!''(")!"*$**$*"%*'"#"%++%'$$+'$&')!"'"+*&)!&!("#*"$'&(&(&*$%+%"
@r1482
TAAAACGATGCACACANGGTTTAGCGCGTACANGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTNTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCNGGAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTCTTTAAGTCCTTTTATTAANACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGNGGCTAGATAGTAAAT
+
0ECD.':A2!%.-!-'990'(A*.$"?5%32#F,</:$67G'BCB'H*?.#@!GH8$;6:"EGB4;"9BF83(0:+@)?4G5EG!3"#$/#>7)9>2/!+26#'C,D/4$.'=37-FE9:C:'G&!A<7;)G+/57+H2GF2)53052<#.=A!3$$A8!$,"&)3<"E#G'3.4#&7@G<=,8-,"<.B>/5(G4*365A?"FC=.H#/=$@10CGH,?#867#'D33$2!;(@45G'C-")855':E../='=7;:019!-G5A2>-/0;+*!=F+CA!7?:90'/;4*?1%#!7(%93<-"?8:*?HAB-@AC(7A"'E=?6FH;1=<-B9*B5;%8#20G%*HA@#07D*&-*>'1&9&98+<DD(5$*'E?4B#,B7'">$-2?=/9+&4
@r1483
CCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGGTTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGNAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGA
+
#-A=:E;%HF/&$;-4>?5.@)<:>B2%@-FC@2"8;5DF=;-@-=@D8ED=09GB@,D%CB2"C>FE9($+(84'1D**-<,7<+1:+0).%/B.2>,@B;6<F6&)9%!FG/%G28<1C7&'CGA;=!8-,"4(/89!=*6-%2:E7:C!5$&*F5--'?A%%&2!'F4-"++-:/?/)5B2%6?7D/+((69B3A>,A8H*77G24%5H,>B$"#9D1.=C%,C=6@%*AB%04A,":B"F'6@,%G,<>8>H/,:$</AF&:BDAE:G&30
@r1484
AGTTGTGGCTTGGCTCTNCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCNGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATNAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCNTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTA
+
8$-D+/G&@7!0"E:?(';<3AB1D8>94"A+7C8%'+:(-/GF"B2>=:2FE04F00G.+*&A":E6)7+4/<@#G+HB*"@D!::,BD&66H=@6<C"B"487,,%*-*GD(%.*8E+*A20$,"/4>4"B@HGE7A-D<0/"=@E2=G<'D4.=(<)0B,>':#H0?+4,0=2,C@1G$796+4A55C+BE9,7C@G,+G830,/2+;2:,?E7..?3)&?80'%*?$?=16@EH<CAE((2-29#2F/4%66-''0,>??"D>0%C8G5H-C@.3CEGA28&7:/B'2-!+*-+F0.B9BH#"'9*3:F6="8(G),2G-=E+G>$AA18;44D1&GH.B?46DC(%53%E5'E,;%;>;;=@>F</;6$"0*)&?=H"2+428E"D'0:.8>#7C
@r1485
GGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCAGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGC
+
.9&*##4FF)A5B*A@>,$8+GC>'=GC6AA;=27C0$E@ACG9@<A!"92,,681G,?F@&>%",D47(B5&1$&,B)0/>;>"@+&G#!+&E/$<7&0"/*B(*"37703(2-$C(!'?:&4F3988:(<@*%4G9"$F/4*5@)?G=A47=(499."?6><..;%162D0!$+E"<@6=423H">">)2
@r1486
AATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATNTCTGTTATGAGCGAGGAGCGGAAGTTAACATTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATGGTTAGGCGNTACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCNCGTTAAGTTCAATNCTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAANAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAAAATAAGGCATNCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCT
+
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
@r1487
CTTTTGAAACGGTTCGACCTTCTTATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATCTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCTACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCAT
+
1'@.?,)(;+CA?+4GF%:EF<F+E<@;8AH96'$#D2%"$7'/:8-'8@;7;7!<"<1-%@+%$=E8#4=D=)2>+%0)=!'A9"4):.?37:8"$433?E'-5+*1-(%/:=#?'A42D,<A';/3G;1#'HC/?<,(>A@>=,1D8F&6;F*@#B@>91:>F7%0+/<!0;'+#B8C1B)9DGFF6>"$-&$H?H'/%97G8=#<$'D/,9=5:.B($2F<5H.7"1%%!2;'FH-+1%-+5$)'D*?!G<F41>70($##BB(!F;F41FBB1CD0H?G,EB::0''
@r1488
GCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAAGCTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGNGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCNTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTACCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTNGCTGGGAAAAACCGTTACCCCATTGNTGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCNAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAANAAAG
+
5$DE0$,47#&FC&&>6@0B:@23HC9H%C3B..7/@=?#!/G+0:CF#B4::/F/@):8,931?1B7B;674+#<@.-"B;:63EA&.6C7F.G:&3;C()*=/H$)DF$D.<++!.14/AF,$E99@46.!.7;=H>.19C?HE4G1!!<&?":?H,8/"*/(8@3&>!-#+B0A&7&B81C"E9!"/804'2%'&$%;/%B$;$57E*,)'!!&8G)B(:7H1>92"@?7A**C/$C97#FGD>0'DH7E/.H#H6=>2B1-%$C&/0>*;8-4!6<:9C'D!53/@0>E/@:+A(!*5,8EB*->,@9-)D(.;#DGF&?1%-":=D&DB2::G7,9>&";:$3CFA"EG5H71$8*B*1G6!36;@D/!/A")$H.D&%(4:53%#;+67CF?,-0&AEEG:%22D?#99$F8DH1;2H)EB8-+F85-8,D?
@r1489
GATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACTGTGAAGGTAGAAGNCAAGCTACCTGTATTTGGCGATATATTAANGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTNAACCCGTCACCTCAATTTTCAGAC
+
6771"0&=6+9-F"HC'E"?6D=%46$043H'2%.',!1HF;8'+D<+&A*"H6;A:1>C%/*&:5*+*93$&4/1=)A435>C/<=(,C#3,H):48&&$2G))++:4D%"5>AG?GEC:)8F7:&-,-676HG0=-#?A-.,"HG#2&=::!HBC:%@/"DB&3*%H=D*4840@1B)'A/0"9F)A:&E3=#'48>&#B7<*=D4?';E*#A)"9G-.7'"D!DD45.>
@r1490
GCGACGAGTACATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGCTATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGNCAGCGACATGGTTTGCTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCT
+
/B+4=/1.A1!))$7@6?7:56".D59$;?9A!9HG7*7)"F(GCE")7C5#;)B&*587E<B87'A"/&9E/5#&/2:H925*1D);:/4>#H/;<'#GA1(+*#;.CF?@"<199=D+@H#"!078<131F/01*2H-)$!&H;$)=D)43+-FA,6H+@/B./E1'#.&79/(1F*@.324B0'(A0,0',810=?=<-<'+C2((?5A3;(,CG0"2G$D9>5,**4.0$($:!,#,F=E.65+B=&%G;;(=<!-D7(?,-A)A*E7$,2*B*E1,,7(>?294E7)##=7D6'6:?16C?E->7E=!3&==03,GG##G5AE:3-%;:HE$-";6(D500H(%=<0$8$3"987D9E-H/.;+,;$G$-;C3G+72@6*'==;E>B2B*$04&211,4F=""=%B>-*(-!<<D6B"&*#:6(;B-
@r1491
ACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTANCGTCACCACGCNGCGAACGATGGCCTCTTCCAGCCTGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGNTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTNACCA
+
7%8%:;=D.8"89('8"#$+AF8DHG&'4*BE-;('(6AF;5AA?63B%@(!1653<-58#"H@).E4H?:G<-6B@=&/*8BG<!&1?#$+>>+@5(/.7BA;8%$-!;:(B,#@3+C2?H.F:&C4/;.*4>&'GGC6&D>2/(!&=0%FD60$+ADB9!!;@!648509;F>0?@#BE9!6$'205%?/"23=:4#0)C/;0;/$!%2"FC0.#%49-B.&(E"E-E4(9>1+36"<E+D#:4:-%D7G"(>!81!%;F#=<!>!!9;9/7FHB?D&H"/=3>E1>!#'@(C,C)%/!*B1;=%&%7*.24.4>0H6,4FF"9+E,8E,A?<&*@E)H9$>H8&:972)$;$'.HH5?*0:HH$C7)7.@&4.&(9/C.9F2%5.
@r1492
CATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGNCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCNTCCTCATATAAAAAGTATTCGTTCACTTCCGATAA
+
GB--9/=E*$F44=D9;!*!0:-8=$2&9G8<0!4A--!AC,"HA/##56G#!"$&F,C.>>H)7)7)/HF06)-%)2?$=;7F*>2-+GE!.=0;64.387(1:8(G36;2C0%'3#B&&@@-<H!<3/
@r1493
ATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTNAGCTCAATCCTC
+
.4H>D#&6A9+";72=3%D!(7$1FBB'>BB%/A@4/G%6@D@;@&HB>:8(=!/@73GHG
@r1494
NATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAANAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAAT
+
"7>+@@<4:/,8>!6E%1&;*<:':>E3%/;:1=G3%D'59@9+H-9&=@39,<?B(F5?EBG--4+16ABD3<-$3>'3"=D.7GE!>,DH'H@F5=A%A73<6!85G>@F17E!?0;4=*1780-07$@!?)";D5/A7H3-+7-E;3,"8D!;C8B+&C>!7571":E
@r1495
GATNNTANTAATNTTNNGGGTNNCTNNNTNTTGNNNNTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAATATAAGGCACTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTANTGTCTTTGATGAGCATGGTGAAAAATGCGAAATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAANTTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCNTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCGNACATTGAAAATGAAAGCGTCCTTAACNCCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGANAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGT
+
*&%&*#"(&($%')#$"$%$&")*)$*!))%''!#$!+!*"#))$'(*!($#"#+&*#%%%#'%#+*"*&"*"+##(")"+"*&(&(()'"#&"&$+(*'++(%)*'!'#$$("&(#('%'%##!#')#%+%&)&%'!$!&&#*)#'##(&*"*$$((('*%$(!&!&#*'#($)$"!'*+)"%''""'&'!$+"#&%")!$'((&!#**%)+$&#'#$%("+&$#*+*)'")*""$"+#"(*$##&!#()!!$!!'!#%#$&$)'*)$(("&""+#!$'&+!'(+#("&*##%""'"+'&%!*'*"!&)+%*#&$%*#!#!"#%"!**#(*)))%!#!*#$%%'""%!!)+#+*#(&+!#&*)!"((+#(**+'*#*$*!+%&+(*!&!(!&((#+()$"%!$(#$+*+"!*&&#"+$$)+))+'$#&%*"$%&'%*)$(%+!+(&%"$)#&)!"!$)*$''!*)++%+#"#"%+'+*$'#**%*%'*+(*(*)'##&("(!(!(#+$((%*(+#+
@r1496
GCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGNACGGTGGAAAC
+
@%9>/@24#GA2-+-7,28@A#@.6<G=?7CGB$-(?=GHF'<(65E4&'1EG6'=*'-
@r1497
ACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTANATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCAT
+
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
@r1498
AANGGTTNCTCTCCTAAANNNCAGGACGCTGTGGCATTGCAGCAGNTNAAGGAACGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGNAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTCNGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCANTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGGGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTNATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTNTATTAATGAGCAGTGCAGATAGAGTAGCCCATATCGATGGGCAACTCATGCAATTATTGT
+
'*#("(("%(*''"%)*&!*!(((+!%#%'%)$*&')'((**))%"'))!!%'#'(+!""#"'!*'$!(++%#!)+##!)%&)*!#!"+&)*))*#!!&%(#%++)!)($#&*))*&%$$')'&%$'%"#!#$!&+&&%%'(&*$)+*%"'(*$*)))"*'!('+&"'($(()!$#+"'&&+*$&&&)&$'#"((#(#'"*+"+%(*+$&$+!*"'*(*!&"+))$"$%)$**%"*$"%'%(+#!#"*$$%#)'+')(+('')&%)+$++)"'()(($+$!"$+"%!#+(+!'!&(%(%**("('!##*+&$"!+&%#%#*+&+%"$&+("!%*$&#++%('+(&**%'(&&+(&&+*&#(+#')$!#$'+"*'$&(+*"'%()'+""#)(&''%"#)($()(!%%*((+(+#!("%&(('*(+$(*&"$%'%"("!()&#"))))#*'%&&'+$%"&+"&*#+%*))%%&"%$##+(!#!'%$**")(!''($(&()'(&$"#$"&+!)!!!'&()+#'"#*&")$#"%($%&#)+'**##&$%+(!%$"$(!'$"#*#"%&+'!&$)%(%)*&$%$""$$!*)+(!$)&(+$!$#("%+!%#&&#!('"$(%%#)!))$*%($))%*#'*&'&!'&)!+)*%+&')$)($+#("+""+"&$+!$!*''('%)()#')#&%!"#+##*%#+'+*"*(%&&(%)'+)#!)$$!$#*%!+$+##&
@r1499
TTNCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTNTGATCTATTGCTGGTTTCTTTCCCNTTCATCCAGCAGTTCCAGCACAAT
+
D$%)9;(C9E=H:*1"F#2%",>=)A**!;H''%#,=G3<2=6,2.C@37HFH/D)90137.E'?;EF-!C@$>3H,1=353+5>GEDH%5!4ACBG(G-,=D:+>:B'&G6620
@r1500
ATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTNTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAANTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGG
+
>)-@G!>?#,%%"/<4B$<91><?D(%H?GA%0@/A-4G?#8D$/#C7-,BH>."+0)?+)4>EH4C=).(GEA8.9HDC=1??%7(2&;&113@FB:;;D@:F'#1#/;6;6*7(?'C?%%7+/4FH(DG1/=1<FAB>4-<(!B!:?*15EHC&B)"<-E7.-%/>$7;3=F8:-:5B5;:C".A3+E%$E-91#F!FB(4=$H!7,6B%,D3%","*G&+739.1#7H8+#5%#<-%0;F189H'9:5D'G)GA2,,"/@&6HAA9D7?+->/3"&+>2F@,0A.?A;>?(:->C?!=41;+6!,;$A!B=0+!+DC>8GE<FGA5")B*3$5:@&HEFE2:DF&<&!*;%B/B>D/4<;2E4(-D/!9=;190>:A2$F+CC+$D:/4*;$5='85:B?05)6(;?-"9
@r1501
CTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATNGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGAGCCGCAGAAA
+
+#5+1=C8*ED:C)C.9E?<8);'=;-2'B&B&4D%:BD+@E+0))?;>(?+03.9(!+E3A"*2*,-'1';*!G%,7>=/86G,52G=>DE:=::1/<GG"B@/B3=;B-90+@3%!<(
@r1502
ANCNNTTTGNCANGGAANNTGTGAAGTTCTGGGATCNACCGCTCACCNTATTGCAGGTTGATATCAACCCGGAGCTTGGACNGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGNTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAANNAGTGTGATGACCATTTCGGGCGAGGTAATTACACCACGTGGATTGGCATCAGAGCTGCTGAACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCNGACTTTGAGAAGGAAGATATCCTCGCATGGNGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGNAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACCTGCCTGCGAAGATGAGGAGGGATTGCAGCGT
+
(%("&'**#!'&"$&))"!$+%'"('(*$&+#&(!!&'$('$%&%!$+#+")(#&+"++$"*#"%'$"(&(!!!*!%"'+&%*+&&#&$"#$((+$$(!)(*'("!)*+&%"*)$#!"')+%%+'()(('+*#$!*%&(+"&*!)'+('!!&"+!'"*"#&#!)('**%#%&#!!'+%!+)"'!+'&$#!!#!$&"$(+!"+#)))"!&&&!$*%)$+&*$&&!'+'"%''*'(#&!!&)!!$')"%#)!+))+!&+()%'+%'!#!!(&+)%+)#)$(#(%&%(''+&+(+&(&!'"++"%+%"#)#*!&)&+!)#&*+&!)**#'&##$)&"$#&+)!'$)""$#)##("+!'*+(((#"(*+!'$+%"#)('+!&+$"$#!!!*+$+&%"'!$$%!"+$%%(%')'!&('&'((++)+&&&#+$'(*&#!('*%!)"!"%)')#)"%()!()!*$$%!!))('%&'&#&"'))+)')(#!&'!%"*#&)'&$(!
@r1503
AAAACAAGGTGATTGACCAACATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGC
+
$/%>$"D'>(4?H<9E?B>?!>)%=$7+27($;>($8D"4$(16F=+F9,C/(D&0/<#HF9:<85!(+9%-9*35G25,./2A1,3.-5%(;403?=>?3+/!-+9B)!9%)F*F8';
@r1504
AGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTNCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGAT
+
)A5882>8AEA=5:=9%#9.8?H%$H8,'%8@:1C!'"6*'-08FC7#/:+%CGG,#="'$6&@,>G5=</0=,>@;+BA2$F56F&35),*%B-)@3/E.>H:7431A'G2<3$21((>+??D-G%<4*?#15B1B07+"':G6/G3.@>%!C580@C3*(;5F0;@#DDF.+6'C$7'1'F)7:>G6!=3=8G<#2;.A13DE9D68G=B1?>;#2)+0F%B0!*0#H,"-3>4@9<:<*F&">G)F4'G/=&:9+F55@5G&$6*0.>&&2;"19-6E8!>D3F%;!!5A*GH
@r1505
CAGNGCTGNGCANTNTTCCAGNTNTNGGNNCCACCATGACTAACGCGCTTGCGGGTAAACAACCGACGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGCCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCNTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATG
+
'(&"#))$%&"')*$%)%)*'$'"&#"'#"'+%'**'&+$#)***+$%$$$"!'"!%*)!!+')$"**'&!(*#&+$("$+%!!"#%#$%&($+*!&('(%%#&(*$#')+*)'")&#)+)%!'!%"%(#!%)(%(('('&(()$"&&#(%*$*'#*+'))%%$**(+"'&($%)&&&!%!*'+&+*%#!'$((('%"#"$$**$*'!"#&((%#+*+$')!+%*($("!*#$#+!&')*+*!+!$(%)""+)+"#*##'"$&+%!)&&'))!#&#%'))(+'&$#&)'))'%%!)''#$("$%)!##%++$"*%!$+")%'$"+(+)%&&#'$&!$*!+'#"+(**$!%+*)$%""$*)*('*""&&$+!$*&$+'"'+
@r1506
AGCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTNATGCGCGCACGAAAAGCATCANGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGAAGTTTGTCCGCAAGANTCTATGAGACGCAGATAAGCGATAAGTTTTCTCAACATCTTCTCGGGCATAAGTCGGACACCATGNCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAANTCAGATACTGATTTTATTTTGACTGATAGTGACCTGTNCGTTGCAACAAATTGATAAGCAATGCNTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATT
+
%$!D:;4G906#=DE85&2B:2,$0$('-?B=:05&,D$B@*8(9E)517&";H115<B3'.94>3+='<A'534B-G@D*(A%D*-@A:<8D;3,1A26:--;9"8-<!F+CG?/68$F76)&A2'BAD57C30!3</1/&E=96-+E).53&5=)96-/7@)AE=)3EAB08A$>$!CC>;&AB*@?FDC1A<>H7>A=)+8H<0FE>C"GE8=3?C:0.4+D@09:=''1A$;GFCGA:E%C50#)46E3A<&=!16;C?90C$5@@D.;)/9!+*9!11&<*E6F%0D%=6H-F4E09+.!6?,CF/=GD+G1?.@A3A9-:17&D:4D9GC*6='*02?;@?/+#0>47D59+'=#1<@A<%/71
@r1507
ATGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCNCCGCCATCAGCGTGTTGTAATCCGCCTCCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCGTTCTGCGCCTCTACGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTATGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCA
+
)+%&)+((%)!)*("!$$#*$("+'%'*'*%&*#!"$'!+%)'*#"$!))%!&#$*&)!+'$)*$**!&(&('%!&&"%)*&$'((+$)&**$)+!"*+!+*'(%)"#))#!%%!!*)"%#$%)((+($**$+#(!$&%*&$!#+'%!++'%(')!"'#'*++)#"'(&#!#'&(*""#*$+"*#(+&#'#*+"%&*#%"*"%#&(*'#+$++''+)+$(!+&"+!%(&*#(%"%%+*()%(")'%$%)*%$""($&&($"#%")+%!%+*#!***&!'#)#($+*#+)(+"))&)%"%(*'#)*!*$#$'+)#'#&%'"""("')('''#(+
@r1508
GCAAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCC
+
<+"8$%C!*<-8%HH0F92&<@>E#DDC#8'<(,0:+2#4:.#%!%'/()G?<B?;B/!1D+4+F4&<$D?5E1BH4;')3,(-!9>E$7!>)44!-6",-<%*6
@r1509
CCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTTGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTCAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGCACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCA
+
04473&A.-B09H-;#;@4G)(0?)7&>#68!-"-7#EE41=;@H'CB'F0-BFGB3FB85".19,:'H=E5"3*06>7D2F9(+A'*4';8%,:20"*<*?7">G725@ADB>69$C59=3?2(*9A-/)+"*!31$%02G9F;)$+(@@/(C"'63??H=D+><9"GD$F!70;?7*E+"C7/&G+10,,C!%@>0,B)F8+3&&4E:/5%/8144-B:G*/G!C4>>F;GG!753G%E%D5G3F:)6(D25*FF;H1E</$1DF=0+GH:749@AC)&().@D"DDA&%8A.-8E01-,9H!/B'(><7*597+.8><A+D:A+%-$2:'.:'9<F:<A#7/7?9-""*!4G.63=B!F)&32)8/):D4%
@r1510
GAANTCANNANGNGNCNNNNNNCNNNNGNCTCCNTGTNGNNNCGTNNNNCNTAATGGGNATGNCCCNTCNNCANATNTNCATNTGGNCGNANCGGTTTNNGCTCNTTNNNNNNTNACNAANTANGCCNCNTNACNGACNNGGNCNGNNNNACATNNNACTGCNTNNNGCNNGGNANCCNNNNCCATGNNANATNGNNNGGANTCGNNNNNNATNCGTNGNACANATTANAGCNNGGN
+
"$$"!$#""#$$!"$$#!!$"#"!$!!$""##$"$#$""""$!!"!$#!$#"!#$!$!$##$""$$!"##$"""$#$#!""$$!#$!"$#!!#!#!!"$!##"$$"!!"!$#"$#""!!$"$$!!!###""#!"!"#!!#!$$#"$!$#!""$"##$!""$$#"$$!$$$#!$""""!"!!#"!#$$"!##$#"!"!!$!""$$$!!"#!#"##$$$#$#$$$$#""$!$"$"!##"
@r1511
GTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCNACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCCAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTAACCGCTCCCCTTATAANCCCACAGGGTGGTCCCGGCACCTTTCACCGGCCTTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCTAATCTGACAGTGCNGGGATATCGCTCATCACCGGATAAATCCGGGACCCCATCCACGCATCCAGCTCTGAATCCGGCACCTCAGCAGGCAGGAAAACTTCGATNTGCAGCTCCGTGCCATGTATCGCTGNCCAGCTCTTCGCCCGTGTATTCCGCGCCGGTGAGATAAACGGCAACTTCCGGAAAATCCGCCTCATCAAAAANAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCA
+
+$&%%'+!'+'($*%!%#)%+&("!%'"%$(!+$"#"%'"#)+()$*#"$'+$!*$#$!!$(+&')'"'$#'(!*(&*(*(&%%##$*$%))&%('%!"!#&#%+"+$%%!(+$"#+)$$#&*+('!$+$&$#%##"&$"%#+("!+"$*(#&%+##(*#*!'$%"&$#('*("'%!(')''+'$&+")%#%%*!((#!*(+%!)*&(#'"')%"+%$)(*+"$$%(+)%#&!%%&#*#!(+!%+$"*$("+)"&*(#!)$)+++&'#%#(*)$+*'(*'%+*!%(!+!'**+'&)"%)"'+$+&'!&*!%)+)%!$*)$'!$+'+()!$')!#)%!!#&(!)$+%+*%&')"+$&!"(*)+!*+$&$'#(%+(!!#$+'!$$#'"&#*#')"&!*$%&'!'&%$+"#($#''')&))&"+#+)!+&&+!%&!)&!&&("&$+)(*"""#&(((*%)!*)'%))#+"%+"&"%$+#&)*#&()"%*%')*+*&*$+$+("*$#%"$!$#'#(!$%%!+'!"&!+#(($"*#)*($)"#"!)(+$#&)%*$$(+!$'"#)'*#''())!&"$'"(&*$$*+'!$"++*)&$#(+$$&*''(%++)*(''(%)($$+"!)$*)(*$)"*+&"&$&!()%#($"'&%#&'+(&'*!)&)"!%!%(!"%#&(!*&)!)&)"&#"&+**!$*%'($)!+$*#("+#*#&$%&&'!!+)*!&+'***$$!'"$*$(+%%!+$!+"++&&+)'%"*$&**+!+"##))#&$*#&&)($$%)&+()))'((!")(+%$%)(""&("!#)%(&+%'!')'+$&(&$'"%+*(%'!&(+"'!#!+'$''"%($*&*"!(*
@r1512
CGGTGCTGGGTACGGAAGTGAACTATGAAACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTTCAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCAC
+
#((+!&+#&)%"($$"!!++"***)((#+"++)$#%+!+"&$!"&'$%$&&!'(!!"'!*#!"*#'()!$"(!))$+%"&!#+#$(%+")#("%*"*&#)(#"'''***''*&&*#+#+)%*#)""&#$*(&$)%*"+*'('##'%&$'''(!+##!(!#*$%#!#"%#$%%*$'+&)*"&"*("%"$'&++$+"+$+$
@r1513
NAGTCNCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACANGTCCGACAACNCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGNAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGNCCACCCTTCCCACCCTTCTGGGGGCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTNGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCNGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCG
+
$$$!#''+)&!%$$*("!%)"%#$%$*#&+%#+)!#'*#&%++#&&$*"!$!"($"$$('%#$&&"**#)!*&"++'#++$$$$))'%&)+#%"+&&'((%*!$*'+&%!$#$)&!*&#("%!"&#%"+##+')&+*%"*&('*!&!'**#')"(!&''#)+#*+$'"&#(%&''#")+++#'#''"++#$%%*%%+))&+%)($*'!'"$$%(("*+%(!#!('*%)+*)(#&*((*+&#$(*'"$!(*!+&()#"&+$%"$&%%!#")$&%!+#**!"*!!#"&"&)'((&+()'#'#**+(#%*)#!!!'$+!!&!$%*$'))))$+'*'&&&+(%**+'*)$*"'&"*'%'&&#!%"#)&")+&&)#+&)!$*+#$*+")"##%&"$+&#%+!)++&&#%$)%*)(%("&'+#(*+')**)$+"*""('$#(')$'&'"*)(())#$##)'+#%)+*(%)'%%(#%$)%'%+)$!('**#+&##+"*%&'"&#$&&*+*)&!!&(%)%%&%$+)#!!$%'"$%(%%%+(+("%#%+('#*($+#%"!)(+#(*!'%''!+&)&!$!"%&$$)++(#'+"&%)%&'$')'"%#&!(&!*!))'#&&)'$$#"(**+'&%+%&""#(('%#(*!#"''&!!"")%&*&'()+'%%*)%)+!)(&!"&+#$+%#&)$)#***$)!+!!)'%)&!&)"+#$()'#!+("#$*)+)#!*#"++"%)'$!&%$'&()#(+#!+)!*%!()(''$)%*$+)""$*)+!'+()'&%#*&!)'+&+"$'$$"&
@r1514
NTNTAGTTCAACCGCAACGTTTCAGCAGTTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATANATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCNTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAANATAGAAAATTACGACGCTTATCGGAAGTGAACGAATNCTTTTTATATGAGGAGGGCTGTNTTTACAAAATCCGGTAGTAACTTGCTAACCA
+
!(!+$)*)*#&%!'$&"!$((%"%)))+&%))!#*$(%+!*#!(*%*&()*!)!+)&&%$+!(''$($!(%%*!()"*$"#+%)$%&#)!&&&(#*#!%&$"*%)'+"'&+$'$+%!*+"'+$)*#)$+%"&)+*()$#!"+%(*)#!$)#*)$%$%'&(*(+$*!#((")'$*!(%'*)!$%'""*#()%%)#&'&%))+!***&%&$#+#"*+#+$"'%!#&#(*+''(*+((**&+!)$**%'%+"%('%'%"*&
@r1515
NGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCNTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTTGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAA
+
%)35/7/?*C4EE4*F(E+68"3&&%9<0A?/G;-B?<)F&41.D*>HHD?(-6+B6(B%:"1$3:,+7?-C?)C6E4=&"C(;9!H"":=3))70.F-3?-!3/6B!/-).5D/H$7;E@9B8#A9./H.6<2+.0#//G1#*9D&-DG((E$&-02,-7#2C=H*)FH9*#B*));>@#<9(5G6?96A7)!G0+>'>B@FHA)97AA@76"G,/)H227'1(5"+%7<>8C93;:.>""2!B:H-A4,H(:!/,=FA&56B>,':2
@r1516
TAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCNGAATAGCTTTAAGAAGGTNATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAGACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGNAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTT
+
?)748F3('/<CCF/&*2;C65#/D2,:,4<36*E+,?F>!3)48D$'E8%-.".:1%F?1>-%+6)D5H)<+6EE848F'"*>FF/&@)B$9"65(G+2F1,%7;1AB3/=C4=&5.(/1=>=GG9=,A-FB6:H($"/;CA;&.-9!/"4'9(F:1*A,$G<0(;-;+*<-!+#78(6"B631C,5#>.>:/'$C:545)C8>46$.7B:=?4$FBE6:,@;31!4?('"'C-"0"E<?:74+.-#4*F)5,9F5+1B))(,=G!G,<G!!><>'>/F.6=)+G3<DG12#1;8FF.@!@3GD8(#-73%:EH$.E.ED#@.%D<./+H+(,'/F&"<>!6=-;=%0!3,;0FA2((:+>""7=$#9
@r1517
ACTGCCCTGGATCGTCTGATGCAGGGGGCNCCGGCACCGATGGCTGCAGGTAACCCGGCATCTGAGGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAANGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGA
+
.17/",G8,B/>2"H"?8HB<D)-<.$99(099".2)5E)F$#/7H(/&)>.'>8&4#BH1%<EF@>)1!180FF'%#4-3!>22$4&!34*=GB73'D,13;4E=1F1E,3#2('+7>-+/%ECC1615:$/":D9>$,77F!*<6%:9(8;2@E&;27C+2E'/>E/2G$A>+%+74E=F+?3!:"&*6A/D@H.A/(9(8'4C.18%*,6";,')0?+C1"8G'>/(D:88!*@*D3.E*)2=>+/01:CA&8H.FD98<9&=-GF@7%
@r1518
ATCGGACTTGCCTGCAAAGATGAGTAGGGATTGCAGCGTGTTTTTAATGAAGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAACTGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGNAAGAACACCAACAG
+
=%B(F&E83E%&8-F)30#'AD?/.%?;5##?@8?+F:9:;!H(>8FEG7;6D,'B"*E;CC%46;%@F$>:5(;@,,)E(&3&3C@AA:D,#:4-3FF/=4..84G<*HE@#-#9B+5E:3@?B/7&C?EHG2H92G!G%-?%EDD+*)%#$9,'7""0B9D3:@$!<B+"E<:0F:5/3&&CCAD5-?)A%D6?0%"$94+"EE6;$>"9C3D3$5<'$=(G,@,?>(5+>0+*@?/+.$-/,-<HD#9G6:B&!3.F7D<5HA>E8.!D*<)A7F41<"38=*C$27C0"0.FB84:!<5%$';&E94DB6'C5G2(=D/E%>&:H5<38G/++F?2?&+7FCG')BB*C.0-17?B!C>A#C<5(A>;7DE@4$;@1;H
@r1519
CCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCNACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACNCCAACATATAGTAACCCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGT
+
E$5@/"="8,",F@$0FHB%!/<)"A2%%*28)/!(CF0'BH(:#B<'EC:C/<!0"+G??=&6@%BD+>10;7B=D/+&*=$G&':+16,#1B5A+>80D::B:G#&(!4(5@37@%G<E#@1(=*#0:>;D(4)774G2&,&B@<!GAE3<.;97/B%EEF=&+7#>)EHG,#-.@8!;<5>1*<74&8E)*$/+@41C2@:0+6*:#A?*)47%B&8#H769$/'+B2.%-6'5G
@r1520
NATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACNCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGGCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGANGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTNATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCNATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCNGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAAT
+
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
@r1521
CAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGAAACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGA
+
4A03/#4&GH0=)8@B9"C@AGB835AC15/%#:'F+H'40)=>0&**.#/-H."-D7F/@H5*+&">BG#F*!$/#!$>9#-3A>35H"0A<";CB2*@%13>3$>62?4HD*8<&=""-@1:>6-.0G@*<'?-!97%$:23:*@&;".=4.4>%671+?3'E3%.*1+4(;%26AH3B*A@43'3E9CG=;B+)".34;(E;</432A+)8)+F.6=6%8D#3!9,FG7E#664:2;+%41G>;A(5?:;'H6$:4+)/6432+FE:);1,$#0"#BC8$6+-"91,>$03$1,>-0A)A/?A!/B;!&?8=+%+.5$4A/:EFD(A5;&8)'=F4#<#+2-&9D4G0H'!<7H20)2*C9-H8G<9)?02.;9'>F(!31<.<#6-&9?!7)=D=%'<-FF:#+>:2;D.!/,F:D&>.
@r1522
TTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGA
+
/:#81%H0EB-C7.@C*%D5709GC(4@#829)</A!*B9D62%6-0-:E6&6=B&/2&.?"DG"5*9*)HA%7107/+48<4GE<=(";.62@)5$'>(@*:'=)=)'D*@-%86C
@r1523
ACNNCGAGCCTTCAGTACGCTTGTCACCCAGGAACGTCGGAGAGCCTGCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGNGAAACGCTTCATGGTGAGNGTGTTATCCCGGTGCTTTTTGCCATACCAC
+
*!&'"++"&#!)"$+#***%%$(!%%+*!)%&!*#")%+#(''+$*%#!*'!*#"$#(&($(!&)*'''+)!$*!&&('%)")+%+))&&!"$&&)"+)&'!')#%++**#"'#'&!&'#*&%#(##$%**#()""#+**'*#"!!+'*$%)+')(!%!+!%"+%)(*)&)"%!(#"')+&!+)*#('++)$!+#*")#")##%%#%"''&!$#"
@r1524
GGNGNCGACAANTGCTTNCGANAACGTAAGGAATTATTACTATGTATACACCAGGCATGATTCTGTTCCGCATANTTATTCCTGATAATTAA
+
$%$)%#&!*%'!%*$)%#&#$&(+&)+$#'%'*%'(&#(+'#!")#(%+&"#*#''&+'#!#"%+&)%%%$!!##'&"#$"#%(!"!++$#(
@r1525
GGNTCNNANNANNAAACATTCATGATNATCNNNTNTTCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCANCCAGATAAGGGTGTTGCGCTGCTTNTGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTNTGGAATAACCGACACGGGCAGACTTCACCACATTCACGTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGNAAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAATATGCCGCAGCCTGTTAACCTGACTGTTCGATNTATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGG
+
$')"'!!&*&&"*))$"!&*&&$("*%&"&"!!"$(*!(')()+%%'''%)'(+"+)'("$%#!*$*%!##%%+#&''"+""'+!%!$#&"+&!"$'*&*)#%+)()*&''((!%"++)"$#$("(!"($##+#+&#"%(!*#'")&'(+))%&!()*(%&)(*%$*!#%)+*$("$&)+*'%**%#&*"++($#'+(("++$'+"!&&")&+)+&+*$+%)"$!!'+&%*&!#$+&!)$("()*#$%*!$!*"("+)#!)+&#&(!*%$$$%(")%$%#(')!)')'""&*!#")'++"#(*"'!(&"('!%+(#&%*('!&$'#*)#$#&!$)*%#($*%'(%$#*"*)*"&)#&))((!)&'##(#'$+''%'*$%&%+")&#*!"(*&%&%*+$""$"#*!+!#)'"(')(##)*&(&'("**'!!&")%(%'(**!+*%&)$'*#""''++)#!$"))"#+*&&&&%!&%%&*&!)$*%$$+'!"&"$$#$)("!"%&%+'##%#%#''++%++)!"'$*!)'%$!*&"(*&$('%&'"%$%"*'*!*"%(%+*$$
@r1526
GGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATAT
+
G4AD#E8H'53=10;05)+(8:%BH17-58F@"*7>(G/E6@+BF+$.=0F.G.:7&FEB%!DEC24E&@0886D(
@r1527
TTNNNACTAGCNCNNGNCNTNTNCNNCTACGNNNANNNANATNANCTCNNAGNAACGNNCTCNNNGTTTGNCNGGGCNCNGNTGNNNCANGNGGANNAGNCNGNGNNNAGGCNTGGNTNNCNGCATNNNNTGGANNCGGNNTNTNCTNAANCGNNNATGGNGNCNANNGNNCNNGNAGANANNTGNNAATCNGNCNNCCANGCANNNATNGNNGCCGCNGAGNTNGNNCTCCNAGNGTNTGNTGGAACTGANNCANAACAAANTTNCNTCANGNCNTGNNGNCNNNCTNNCTCATNANNNCNNGA
+
$!##$$$""###$!!$""!!#""$!$##!$$$""$##"$#!$"$"#!!!$"!$#!#$$#"!#""#"##!"!!"$"#$!!"$!#"#!!!""$!!##!#!!##"!$""!$!!$$"$""!"!!$!#$#"#$!#!#"$!$"$#$#!!""!$##!!$##!!!""$"#"$"$"#!$!"##$$#$$##$$!""#$$#"!!"##!###""#"##"!#"$$$$$""#!"$$"$"$$#!"$$$"!"$!!$$$$"$#"#"##!"#$#!""#!"!##!#!!##"$"$!#$#$!##!"!#"!!!$$""#$#$!$"$$#
@r1528
ACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCGGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGNGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTNAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATCCCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCNTCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGGTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCG
+
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
@r1529
TCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGTATTTTCGCCGCCCCATAAAGTACGCNCACGATTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGNACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCCCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCT
+
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
@r1530
ATTCAGNCAGCACCNCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATG
+
:;5'6+'>)BF#G&458B#8;,1',H/<-,=%6&8CF=?*)C/B7D?"?4)2F$-H85D-012,6E2*+!)
@r1531
CCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCAGTACCTGGGGACGCATAATAGCTTCTNTGCGCCGGACGTTGCCGCGCTAANAGGC
+
',),"9,CH0'(0$'3B1G6,;5"3<DDG1"G"#FD%;9#44,:G3>*(&@CH&A,:<9CD8G:>@;3/G0<62'<&G!"D,$+<8;G9G/1..<;+C'%#>')F(1A/"6).$6:#@CF'C8!1.+)EDH++$';'>?=0('H+B#)"?(18,G
@r1532
CAGTGTCCAGCACCGNCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGNACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCANGCGGTTTCACATAAGACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCG
+
6>C7::#!-21E6"FF0.="DC@;6BD!:?6@B<6(@F1!67-<3!H>%..GB!?49E!D,@.6076&@-#4'@7,3)+!4,*1*1EE4-?)%,<'$8E+77=8%?C!/:,"?&"8+#-H>"%%@78,#F(.;-2$<#1'DG887=B@?A(.:AC2*A$%<"6@G16$*''"E!H6<"*1;5H#"%;040:C""/F>!20B?%9(<65HF3>'(E==<542C.15=1<1C+%@<@9(-?=.6%.F2&A7#@G98B;!4@<CE7'.G*0&;?>2@A0%:9).-8'H*&DGE"@50?@G5;$2%3>H&:+"7
@r1533
CGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATNCAACATGAATAACAGTGGGTTATCCAAACGGAAGCAGAAAGCTAAAGATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACT
+
+&#)('(%+"%)*(&($#$*+)$+(&!*)!#("$&&))&)%#("%!+!!$)'"(#!&##"+)#+&+&)(!!((&##"''%!&#+#+#*+'#%$)*("%'('%$$!&#!%%&+$)&+")"""&$)'!(%&)**!!&%#!!!*'(*+&"
@r1534
CGTCCGNNTCCTGAAGTGATGGCAGAGCGGAAAGAGCATTAT
+
(&$)%'!"'%#("+''$))%()%"%!(**'&"$(("%"#)!'
@r1535
TNGGCAAGNNCTNNCGCCNTAANNTNNTTNTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATCCAACGTTCTCTNCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGT
+
*%$"*(%*#!)$!%!$&)$#*!!!*!%(*+%+'*''("()&('$"(+*))+&$''(+*(#'+%*)($(!'')#"#!'!'!#+''*$&(&*#'!"!)%&$$!$!"$'*"*"+)*!$('*&$)(+)'+$$)$)+'#&$*(+#*'(("#$*#$&)'&')'&'"*"!''"++'(#&#%"+(%%*&#!"$')"((&#)+#('&()()((+**"")(*&$'"##(#*(+#$$
@r1536
GCATACAANTATTCCATGAAGGTTTATAATTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAG
+
?AE0G&2+>9/9EE.@9&9C3F@*B=?,(60(30$-9G.CFEG6EC#::BD/."EH>H5(#>F'H4-56F(59$6.)9>=116/?<)F$;!>C)(":%+HH(
@r1537
CAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAG
+
"(>=%E/1%H;:?E)0/A)"(B<D2EB6:>C67G!!?9H2,00149B"F#D5!.CA:)+29$
@r1538
NNGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATAACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCNCGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATANGGGGAGTTCTGNCNTTCGGTG
+
'&;DE85'.)!B2"86C>2A>2+56C#4<0D?!)->D?)3./"'@<:C.,97@C*-384&1#0;<29B;=="?B->3DAC;,9)(<=5#G7<2"B+G)!$*#E7?#575898)*%-,5A1$!<E269C=8@>.""E-9'FHCA9G*5/38139:G)7>!F#BH@9)-=BD-E-%9?:4,6-98(?E96B:5?,*?>C@@?5!F+D@@-*5G;@.8''&3/,<0<096+-.G9;H,%>G'B&*/*##B4@E2+%:=:5,!9A5C&9H%&1<#!4B9GH&2,<G->8)C&A@?*(!?'DE81HH&;)50)7$FBF+1)"F0<.B;072,":#2;
@r1539
GTTGTAATCGGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCTGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGATGCTCAGCCTTCTTTCGGGCCGCTTCAAGCGCAAGACGGGCCTTTTCACGATCGTCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTNCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATTCCACATGGCTTTGAATGCCCGCGCANTCCTGTCTGCCNAGGTCTCCAGCGNGCCCATGTTCTCNTTCAGGCGGCGGGTCTGGTCATCAAACNCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAANGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGAGACGTTAT
+
*)$(+(!"!&")#(%+*%##"'((&$+!(%&%#$("$#*#!"&%%%!"+&(+#""()*)%)+!!)!+'$&%**!!%#%&+%'%$%%+"!!&&"()'&$"#+$!#*$()%!**$+&'+*("$$#$)$(#&+(*+*+)%$((&+'""$#)&(%*$'#"#'*()+)*(#*%%$)!'%&&#%*)!((%'+'(#+**&"&%+*'"*%(#**'%%(!*(%'$(&#")#'+&$#)!"'+)$*$("*&$'(&&)$$&"$+("&'*(&*+%***&!&!#%)(#$)*+('')%*'!%''&(!)'*#%*")*%*(&%!$!+(+&'#')#&!'("##**&+(&$"***((%)+$%+'$%%#+*$*#%&#($)#($%&!!*(%()!%"("+&+)!+(!"#$")%$((%+)+'(((%"($(("%&'&()$&)(%#'))!*!*(%)%+!+!*$&(+(%'&&'#%"'('&)"#!')%)($%!**")+&"'"!*()+&(%&))$*#)!++*!''((""+'!+'&$%$*##'!&*$(%!&$#$%*")!%)$"')&)**$$(!(+*"*')#(($!($'&#$&%"*&%&%')#&$
@r1540
CGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCA
+
'#+)*("%%)$$"'(!'#'(%)*$(&*+)&(++&#%""'$(
@r1541
NCTCGTTNTNTGATGGTCGCCNCGCTGTTTTTGATGANGCGGATTTTCCGGCAGTTTCCGNTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGGGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCATAGCTGGATGCGTGGATGGAGTCACGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGNCTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTANCAAATCCTACAATGCCGGTGAAAG
+
*""&)&#%'+&"'%)((%%%"%%($%&!"%&'*#$$('$$!+&"+&"%$+!"""'"#(&%#+!&*)#(*)*!%**$*$$*'"+&$+%%"!#!&&#$$&'))(("%''+!'%'$*$*#)$#"#$$(&''$**"&(*&*(+#"+%*%"#+%!#+%'!#"**!)$"#&*!"))#))%(+&&'(%!&$'(())'$!+$)'#(&&*"'+(+&"")&$*"*('&*!'%!*&#"%"(#%%+!()##"&"$$'(#%'*)*)&'!!*+)*(!!#+"(%*"()"*%%!%()#*!+&#&!&(#'#$&+"(*'(&&#&#**"'$($#(()&&$%'*'!*)#"*%'((*+%"+)($')"!*!%%'$#*(*'!#$#((!%*"+$(&)#
@r1542
CGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATNCCATCTCGGCAAGGAGCTGCTGGAAAA
+
4-#HB*B*7/5&6C!94>!:0.(*',<06.-*A$;05)7D*39H<#4064#"A=H+>FB+*!E<EH1%E&!C!A+D&:.$5#
@r1543
NCNGTGNGTAATGCGNNTCTTGTCNTTGCTGTCNTTGCCGCACTTGCGGTGNCAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTNAAACCGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCTTGGGGTTCGCCGCGTCGAAAANGAGCANCACAGTGATGACCGGGGAGGATACG
+
($$#)#$"&')$#")$$%")&)!)#$+#(%)"%&$"$($'))#)"("*"""%(%'&#&*)*#")(*(%"!%#!'+'$+&+*)(&!%+#"(%"%"#%$*&"%'&#)%%"$+'"")#(%+"*#!(***'')!"+%%%*'%&#*$&)$!$'%&+!%&!*)'')'+&&%$)#%(&!!($&""!"'+('+&'"#)+%!)"))()#"((++&)*+&$%&&!"+"(&%)#*("*+#*$"&!##$(%%!%(!'$'"'!++'!#(!&''*%*)&%'&$(')%$$&!#%(%
@r1544
GNTTATCAAGCCCTGTATCAGGACATNGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGNGGGAAGCTGCATGATGCGATGTTATCGGTGCGG
+
*'H1C6!2#@)655,-(@B&4HE<&CG5,1'@2A5.)<=AE2*,DACH5--)9@.*9"6BF16A<:)D6%F"$F6?#9")+C7-1!6)+>)G-;7:B@%)44"7/%G"G"B):7"4724,2F?0BH:C<)=3GE$6+H<3$5
@r1545
ATAGTCGTAGTCATACGGAGAGTCCTGGTATTGTTCCATCACATCC
+
D+#&"2..G4@%D%=4321!7:%#)9#;!#770A:=8(GG>B4%H3
@r1546
TCNTNGTCNNNCNGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAG
+
($!%#'&*!%!$#&%')$$+%'%%"''''!)$'#*#&+)%!"&"$#'+'%#$%+#)$)%&"((+*$+"#('!)$!$'*$)+*!(("(&'"(('#(##&$+!#
@r1547
TTNAAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAANCACCAACCCCTGACTGCCCCATCCCCATCTTTTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATNCGTTAAATGTATCACCGCAAGGGATAAATA
+
)()&(+((!+"))&+$$"%!)$&!"+)&+(%%(%+++&")*)'+'!+)&'#)!(*$'$)$#%&**$$#''&'%&&##!)+)*(+$!$*()#)))(%($*(!&(%&($$&#&%*)!%$)+*$#&+(*!#(%##'%&%%'$"$(*$')$"%*(%*+'#+)!*"(!%*&$+)%()'+!$!&$&)"!*+*+!)!&$%*%&#*!+*$&$'#**#!#%!*&$""')#!'((!("#%&)**)*%&&%%#&'
@r1548
ATGTCCCCGACGATTTTTTCCGCCCTCAGCGTANCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTNCGCATTCACACTGCCACTGATAGCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATT
+
D<,#(D29;F!8E!;2!=H!46,2+%43/?:=#8.E,*F<B$3/02'@1'8>9C&F8E*'F/#4D'8,>+8<.F1.28+5:",.=*C:E&<-3GA5(F*7("4,<,24E2E:<F7'1D11*34BAFF.),6"H7-!2:A.CE*D..+D=;"8)4$6A2(F@A=H
@r1549
ATGTCAGGTGCGATGAATCGTCATTGTATTNCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCANACAGGGTTTAGCGCGTACACGTATTGCATTATGCNAACGCCCNGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTNCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAG
+
#9F8168D%9B!2&H58D<9/A+&(74:93?E2/1:@2+!!D=<E.,/3&4AE6);15&6719F$+73-.$+3:G./#@:@&<%;;F08.8;'D4#.75@85-DE7!D,:)1"&?#H;6C9"!CF5:7B9/)<01)!$*"!$<4"*H:B6!;+/A%<+%:%19A59++;"A43C2HG*19$;#(-H;48&&303/!$'7:<!C$@!A27&(3<G)4CG*&0CG1$+/DH,?1?6!(+%GF;5:H7&DD(H>8.+:,83GA6:48+"?@,:%?7>#.-*C88>H*'37;3>C<.B'.0)AD4>*5$,;'5&=1"'219F>.*"9-69+A*@2=FE.&/7?A$54-6@>*.+GF5:+1'&ABC'>%6D+>#CE?H;8D.H"*'?;-5?2<4"/(6<GA8+#0A#'%%D<C$-)B9G40&@?
@r1550
TGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGC
+
+@)D3!D?+$@!($?":<;7"5&7A.=8>E%/!8!+)A6-5<$,<=19)+AG1$.,E,AG.BC+A<%!%1E@8:*!,06>H5>H9C!D%7@?!,".:2'0#6:(7/E90+6?#%)5#&0*';:5-/*,>0(BGHBE7.3**
@r1551
TGGCCCGCAAGGGCGCCCGTGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATCGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGNCTTGGTGATG
+
D7B)*%.!C)0!.1*@?9C1@F:F'=+!<((&*(.;#(>7)+BA>2;!2/6=>;$"$;9<#@7C=@A4>!:$!,DH!/=*.9/*@,&7F&435G-*4FG&))"74$//C4$<8C;*(81&%.14HB99"4%,,0=5GB#98(,D3G7#1)::G4C
@r1552
GTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCNGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAATAAATCTGATTACTAAACACTGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAAT
+
F1="F87A=E4:)B@+158><D'?-@8/.@@3<1;AB3",G-/?:G9&8C:6+>"A>DF+*.48$1E"-GD@5698G,+.)HC(EE232B<EAD+*)19-/&*(@8?7496",#+#>7FF,=ADC&6A."&7A*#C;19CF4A8GCEG!HD#66623B78+"34)G5<;<24(HG;GC7:;2)#G01%4E,8?,)$$3HD&;??,$??GCGB,H;%F<!#76=1*C5@F?!/>G+2<C;;3)4'1&9!8DG',0H("A-=>*=!B+#)>3!9F6.0*9+<;%CF09"3(@>3&'/,1G,=.A87,)
@r1553
TCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGNAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCNAACATTTATCTGCATCATACCTTCCGAGCATTTANTAANCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATT
+
(#+%")$"&)!&)#$"''!*))!+%('%++!'"'"'*($)&)'!*"$$"*+'+#(&"!(!)$)*'$**'+%%$))"#+!(#'&$$'%&#!!+"#*"+$%""**%)%*&*)*"*&+#(+$)"$#&$*)(*+)&)(*&+*)$)('&)+!)*%'#'+!)!+'))"!**!)$&$((&')(#)*$#)%(&"+((+!+!$%*"%*+"!!"##'&$!*')'!"('(%!%!*##+)!&%*!+"(**!&&%"))+"!&")")*)&(#!*&)''$!+(&#(&("")*#$!*'(
@r1554
GTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAANCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAG
+
)3&'-#117>,8/,E@D&$@2?-B>0D2%?F&4)?CH+A'9%7DGA=-8+GH8:B14E@?1(A1><34)=5DD#FH1C?:2<!+--':5;0*2*409(+!%8+.%#=F+-DF-F/05&$7&!E!+(2@B;EA6E3%-@/4><621$(>9"1B??F2H4%50C#<4!F1+/#/(.8,.ED(@%B?<,%;$0'@;E0B(@#%C*.EE*&772-A72;H*EG&@:>0/5)1&?#7)71%=E05?1BC&@;'GA=;@-G:,5G%)!DB
@r1555
TTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTNATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGANGCTGGTGAGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGGTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCNTCCTTAAANCACTTGTGTGGGCATGAGCNCCCGCGGCCCNTGTTGAACCGCTCAGANTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACC
+
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
@r1556
GCAGGATGTATGTGGTTACANCAAAACAATTCCCATACATNAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCG
+
*AF:4"B"3+;,:86.*B(=+4:@281/B*--'%.A&@=;;-<(83-/GDE>;?=667=.2-5(:0-&<;FB1E>0%&&"6H((.
@r1557
NNTGNNCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGNACTTGTCGGCGTGNAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGNGCGGGCGTATTCTGCAG
+
!%)('")+("(%%%*"(*))#)#'&(!%($&+(*&$)($!&*(%!(+#"&)+()+&*)(%&*%"*$(&&+!*)#$%!*!"*#*"+&!&++)!++'"#$'$)(&+&#)%%$")+)$')!)"#%!+&"*%)&%'"(#+)%)$
@r1558
ACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCGCNCCGGNTGTAATGNTGGCTGACGTTCCCATGTACCCGCGTATCGTTGCATCGGCGCGGNNAATGGAGGATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCTCTCTGTCATTNCGGCTGCCACACNGGCAGAAACACGAAACGCCGTTCCCGG
+
:AH.-*$:1&GE+"EF;@-B.H,>F6A-8!54=,=41E''"(>!=23#A1F41:G:"#1D((.?14>5=<<,C+BH9>($&F$84,D:*>6C8F87G>*+/EH37=>+-H6?!H";/#A(/<%"E976F&/5E2#>.<=1*>=%6FH!D:5BBF5C-4G0.%D6CH,?,C3+C=";,/8.=EE8*>A%!5,73%@67:'EA>/@&%?H90A8C&;(D9A50(!/,5061088E&,#$9;.,(=A/(6*:DD@2%<>FF
@r1559
GGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACNCAAAACATGACGAGAAAC
+
)'+&$'!"!%"'#(&#'")'&!*%#%((+&*#*#&#)'++)#+($&$"+&"%$)&$++$"+*$(+'('"%)!$#*)&%
@r1560
NNGATGTAGCCGATAAACACGCTCNTTATATAAGCGAGATTGCNACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAANCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTNTCTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCNCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACANATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTNTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGANAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGT
+
#$+$#$)%"($#+))*!&+##*#')")%'((!$+%$&#!$$(+)'&%##%(%%)"*+!)##&#++""+#)!($((*'""+(''#++'#)()%*#)**%&+*#%)")*++%!!("#!'+))+!$#'%*&%*($''*$%#+#&$+*$"#((&*!)(('*%##%"*"'"($(%))"!(!#)#%*%)"+#$*&#(*"!$'')%)$)*'#&**")"!%#*)*+*'(()&"&&&')*&!)$!"!%"'!)#!$%%*+&)$*%*"&)&(%'"$"($("&&%'"#$%+$!"*##*(&(*$'%")&"')'('&#%%!)$+"(#+'**!*#*"')&&*$()'#$"""'+('"&%!(*#%$++(&&)#((&"&'$#$(%$'))&%#&#)%+#!(+%$$*')+&'%*(($)#)##((#)'*'""%&+&$'"#+%$*!)*"("&(#%*&)"*"(&'%!"&)%"'&$+%#!"$#"(&$%''')%+*)'!*%*!*(##$%'&!+&%!!&&%%"!(+!*("$%$**%(&&%%#"('"+('*&)#''&**+*%+)$+#"!&&+(*(&&+$"%"&''!"('%$)%#$)(""+$)%!+$!*!!!%'*#)*$(*'('%''%$+(")#!&#&+))"("))+'&))%"*#+*%$'$#&&#*+#'"#
@r1561
CGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTGTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTC
+
3BE09-2%49D>0)#$3$'>%D3D+<88'&G%$=06;.2+%;1-!FH$#8&07,,/0"7%(G.1E=0B.2A24$9(90<C?6HD)>.;A.40)>#'*#21/-!'?/G.6F2;,;7)7F1&+DFE"-(A5A;,)$(!/:F!?<)%<F<<-*,9;+1AHH%D3&/0,><0@G$11=CB,9'=&B
@r1562
GTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATNACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACANTACGCTTACTTCCNCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCNAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTT
+
5+'62$E(B&*(0)/;9=H5H4+'CF<G4DH1%-=%"#2B==6;/&1D+!)&E=5@E0=C<1EA031$(#*.6>+G%,.%G-1"%ED+!(:@:1/*F03!$%,#D;!34*3F491D<?$%*!!>F(!@."?)E3ED5?C"#9*<6#'$98C9/-9@$F2+&6+/("6@=/$*&-$@754;*'7CF;<72B>((#:B/+0G!*/9)D705H0,5(<"#3$/F?)8-3E9B(>#8B;0:<$9#-'&393>,4(E0"4.BAG#!G*>+0A6%)#G>B.G1,6#"#G5693,"3G1DFB6F%3)E0,0>&'<;2:(%$6#5-
@r1563
GNGGTGCTCTGGGAAATCGACCTGACAGAGGNCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCA
+
($A(4&5(%15'D=CH/3?:E-A2%"4=E2#DE9".<A?+2AH54,F2%D'AG#95%;/$4%%>2'<)(%%;?=)=%CE+(6/=?5D)G=7'E2(
@r1564
CCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACNGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCA
+
31!,($-!906+*7;F:A#56:-B>H?8$4!*F(@1A#=/):%'<,7#5?=&AG%#B&>E=)/4G;(35;0DG:3.)$-)3-@?-7>#CB,;F0$(3C?-*?H3=6,&&?6&!3H$B#E37A/AC24H.B&?52""0E"2139%3.'!1D?('@&G3H<7@328?%=8(?FC
@r1565
GCGGTCAAGNNGACCNNTAAAAATTACCCGTCCNGATATTGAGACATTCGGTGAGAACTTAGGTGTTTNAACTCGTGAGGTGTTTTTACTTGAAGTGCCAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAANCCATTCTAAAAAATTATAANGGGCAGATAGGATTAGNAGGTCGNACCGTTTTAAAAGCGATGATAAAGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTNATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAAAACAACAATATAGAATATTAAGCTCGACAGGTCGGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAANGGTTAAATTNGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGNTGAAAAATGTCCATTNTGTGGTGA
+
%)#)'$''$"%*&#("#(%'*!%*$$$&''(#)#)'$$()&+)'"$+((+%("#)))+**"##')%%$#!+%!+!%!'$$*)*&)"("#(!"!#+$%!#)'%$%%+!((&%+(!$#!+"!"++#"")*'*!#*)%*(&+)%#*"#$)&')**+*&&'%"$'+&''$!+%!+*"(")"*%+(+'%&+)!$"(")"'*&'))#$)%*)*)!'"+!*%##+""*#+%"'&%)*%*%""&+&'&("+&#'')'%"*(($%!#*#*'"!"%'$$%%%"%(*')+#!#+!#$)&$'*&*&"'!)(##"%)%'%'%#*##)$")%)(%"'$(#+'%!++#'*!(#'(#&*&(%!#'$$%+("$&+"%))'"*'&"$#""*&)+$+##")*"#+'*%"#&%#&('!##(&&$)#(!)!)$&*('##!!*#!)&+**('($**%$%'"'+$"*#"''()!$)*#$+&'$&$!#*(&'+(%)&&&)((%!")"#)()#&#*"%+*"!"#!&$&"*)!%))#&*+($(')#%%!&*&'$!'!*)$!)&&()*''%#!"#'#!((*!&+#&"'+(&$!("!('$(&+$)%')'##%*%$
@r1566
GTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAAT
+
"D=<,7G6A->**)(>D9F"/E+'E'.#.4+1F">E#A.;../--8,<.7AB=1$>-.76A=
@r1567
AAAAAAGAAAAGATTATTCGTCAGNGCATTCTGGCGAATCCTCTGACCA
+
14&!?4*)%,<9$2,517HC&7.50>!F>@B<3"3B)8=C&9=/>830%
@r1568
TCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGAACTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTA
+
<77C8)%@3(+#DG'E"B'/F=$-&=6;,828$6,$EF':;B)423&427&;.87;<=+<:>.AB8.3HB>C431=6,6-7/
@r1569
TCGTTTAACTTTACCCTTCATCACTAAAGGTCGCCTGTGCGGGTNTTTTTACNGGATTTTTTTATGTCGATGTA
+
*$)+&))+#!*$$$&)+!(('##&'"$'"%!"&%!"!!(#%(")#$'"&"'#$)'##('+***#&+*&($())*
@r1570
CACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTAACGACATAACCGCNGGTGGCATAGCCGCGCANCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTNCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGAC
+
<)D/==536"'+'5&0?(-<1G*;"4.A&2;,>:>&)#951+'43/#9#.C:30'2H'9G/A6'*>$%-<"93:;92C/*255F5CG3.?7@!)&:+H@/#3E0G%(4)'&)!1$&E5;D:)-'DABA..72G'6&C/34F55!!4HA:A/+2*B,++.B-,);1+'D/-B$A,+712DB<5#',!=F3.$)-9<D87>G61?5-0"36E61.3'D.7;0!;@@89H4?F55#D)1),#1"@9<$E5D!.=(CA%%,'"!)864%'%5-:3'@=GG)8.212)9/CE>'",G9=&6!=7-;0G;2G3<4-5G422H(D7:.+)(EA)6/&.E30.:5;4E#8D7!1F<$)7>CA55@E6>F(%79?).49H8=3B16=@!:585)E8A0DC@=5?:D86D&"%0/2C#D%,;::;6E%)4E6#,%'8(=*/8"&8
@r1571
NCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGC
+
!-796!E>4.&EF:58/H34,E"""*8DHA"B)5/,$4)G.&6EGA./;3G"HD&;G<@/##0B2&F23.2;2@0-2(8&70-43G$C@F&=FBH54A67A2*A)%4#)6++30=00F612E/:6F9*4,B=,;*%EEF1H*,)+1G0$C=/2
@r1572
CCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCTACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCGGCCACAGCCCGGCGCGGGGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCCGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACNGCGCATCGCCGAGCAGAAATCGCTGAG
+
9-/<-&+2(7=:!:C"C4F$.:G(4#%1::FB,AF.-6/8:G#*-!#/%3,H-F0(@==@!&8:GC'%40'*05#0F30"519+#%@/=2BH.D?C73.C-46(<>C5!9*B$*'AC5<(;<B2!#8+E0&AAF:&36'=$D#'82:-(@34.FA:59%;!.-%FE#$11@"4C/4=F*8)B%&:,H95D+4@D3/C8F157-GF-,&"0=!.9G)$,?(D4<E=D(D1+"0F6/H+!+B!:/*-:&-!.,%5H7+!54&1/!&G<A&*3<"F9(%.?F(E8<(H@'B?=,')B;2>(!D:#H<@1>D:1C<E#EF1@<+.5*?"9);CH7@./A@"D*6'G6$33(3;+7%$5CD4#=9:%-88?(9904.>G/-9*$D(:)G&.?E"?184EE$9,)92@!=*$'$&(*?F+'!3/(B4*,*BE43EA9@.#@.)()=F76.D*8C'(C56G0>(4E+.+:!6E0,=!;8)/&:!*1GC1FC.1;>9A*F:/"
@r1573
NCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTNGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGNGTTCCGGCTG
+
$B-7;!2H*,!44,E#E8(4)!-CF(F%2-4:*/<,$+.(&5B0@2B'8?;6*9?*0!&2..32'"?"HF-0<:11A-$B;<FF07(C/1E@E"2+++",&#4E##*9%;=8D?C/.EBDC82!/9#0')G1)06$8C2F>=A;4>E*!A(7!!(784),3%"#E73"*7)H*HEC?.&47*G;:*)#=0D64%H69!D2(D":+-@GHF"
@r1574
NAAATTGCTATAAGCAGAGCNTGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTTTTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTANTCTGGTGAAGTTTTTCCTCTGTCATTACGTCATNGCCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACANCTGTTCATATCCTCANAGATANAAAATCGCCCTGACACTGGAGGGCAAAGAAGATTTCCAATAGTCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTANTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTAGT
+
*&++)+#"%!*)))#*'+"&&!+%""+#+'"#+#*"%%$)#$'"))%&"*#(*!!('#+!&$)$$(("%"!$)!)'"#)&'#$&")'%+')!($"!&$+%)'*'++)$)$"*#'!("&!(*''#&"(*(##$()*)$"+')$!(($"%*&(#$"(&*&+%!)"#((*)%')'*"*%"%)*&+&$'&')'""$!"&($'')%'#&'**#!&+$)&&*#$'"!)*#$&++'&++)#"!"%&!&"+((+**"!!*('+++$'"+&+%!)*!+%+''#*+*)"+"'"'+""#%'#)"$&'"#('+(!*'*+&&$)"%+*$+"#*)'#*&&*$)()%('")%)%&'*(%$&#&'*&!")$%"+*$*)(')''(*$+()*#'((+"(#($*)!"#!$$*$%('$+++%)&(&+#%''!!&+*$&'+&+'#$(%)#+%$'))!+)$)!+%#
@r1575
ATGGATCATTATTCCATTTTTCAATAGCATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTNTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTANTATTATTATTATCATTCATTATNTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCNGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGANAATTTGTACCACCTCCCACCGACCATCTATGACTGTACTCCA
+
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
@r1576
TTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAANTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGAAAGGCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCANGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGA
+
7'A.3A370%)#2:C!(4%#9:+88:@%FG!(H%GB#++5@=D3/8.D7A;H9>'67'H*(H'>2+1E>*D0#+%:6:C'?"!7F7D$-"G?4#(+)"&=&C=DF.5<!50&;"E,4D>D;H461#/79!$:*F+5&.-'76C05&:!DA'$844D*07;-=D<&.B&!5@.G,2;%6<+6A-E'1/-318,6,9!2);C%&D,:1D4+DE=C0&4F5':5497?2,$2!4B59E-=.-76-;3,26$$E?%,>/0H+CFF1#.>+3?&GEE:46B+$.G=5C>#45.B.CBC)GF:<2-3/'AF.#D'-G*E,#'&<CH(4.,1>&ECA1D86H82>$'.H(7)14&F==A)!6/F9#9(A??(G6D+@F2<>7D6;EC>.C=5<!.=G0*7.6."2:&+%2@:)>=<+%#EHH@1"1>">-3ABC+#6#2);;,?&9?1#<3>";E*-49
@r1577
NTCNGATNTCTNGCTGTANGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAANACCAGGACTATCCGTATNACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCGTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCNGACTTGNTCTGATTATTGGAAATCTTCTTTGACCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGACATCGACCATGACGTAATGACAGAGGGAAAACTTCACCAGATTANTAATTNCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCNCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGTTATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAAGAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGATCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGAATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGNTCAAACACTTATGGCTATCCAGACTAAATTCACTATCT
+
$%'#$%%"&(&!*++"$&'$$!++*'+"*(%)%#(('*""$$%+&+''#'*')*("+$)$&)(*$*('$!&'#+##%$'$&+''&#'&#*"!*"(+!!!&$'*&"(((&&'%#'(#+$$"!#!+$$&$(&#++""(#!(!)%(+%'!!*#!#)(')#!)$&'!&))#!##)#""'"%%'&%++#)$)(+%'$)()!'!((++"'')('(&&#!#+)'&+(%'+#&)&(&"("#+#&*('+&&$"%"(&$&!"%''%*#(+&#'%&(*'"!#+("'")#+(+*!!*%$**''"&+((!+$&'&%'($)!(%%#(!+$!('*(+$*"!%+%&#"")%#%$+"&%!'!'&'(*#('#%'")$#'"+)#%$++!'""(*!*#$%*$'(&')'#!)%'#*)+&$'%"*+(%(*%*('"#'$)*+&&"#%'%$"(!&%++$%*!"!!''%+$#"*("!%&$*$(&*#!'((+)##$'(&&&(*("%&+)$#&%+%()%+$++#)'&'%!(#'))$&'$*(&&)+*"!#!**%%"+%('%'(+!'(&&*)"%)""$+(#(#')'$(!#)$$&""#!!"(()&$"%%!#"$(#'*'$#(+'+'*+'$!##%"*%&*)"#"+%!*&%+*%*($!(''&(()!'&'*%(+!"*!$%%"'!+&#$&+#("+"$#"*))*#"%%''%!'(!(%&$!$#+*#$()!+%)(#&*!*&!**#%#"%"%*$!$)"+)!+)($+#!#%%!**!"%&+'&*"!"!&%%*%(%)(#)&%!$!"!*++(#*)!"#'#('#((%!"!+&#)*#&')&&"!')+&"$)&'"#!%'*)""$+(!%+$"!)%&'('*'+)#"#!'(%**)%%$"#)!#+')*(+#))$+!*'"$)!$"#""')"(&'#'%%(+)$'('&(((*!#&&$&'(''+(%'+*+$+"($$"!+*&&%&$%'&'$#"+$(+)&&!"&()*'+&%'(((""+)+++!'&*!$+#!))'%$))()$'"%&(&$%#+%&'$)&!+$#!+$"#'!)')%*#$!%)&+!%!)'")'('!#''%#+$"*("!$)##"%''+"#$$#)+%+#'*&&"&#$+%###(*"%*$%'&&!&&#*+&""+#'*")'%*&(#'#!)(+($(+!"("'+(!$$%++!++*&%#!)""&('&(+!'&!+&(*!
@r1578
ANCGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGT
+
&!*+!)(+%!'&#$*&"(%*(&*#*(*&$$*$#)($$"%&'!&(#+'%%+$*!')"$#++"!'&+("""'$'%')"!"#*%$+$'*&$(&&(*')")#)*)"*#%(''!
@r1579
TCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGNCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAA
+
('G()D=*C8HC+B%$0&(45*<G=#:BFA00G2493'<5*B*0%@>D++;01:2C!8*G;'/=6$&AF0D7>6:)&A3?:3!>4,>02!50>)930*&0>?B05@&>"&-/9&,?=D6<43/?9&B?E;D<'E>>6A1;+"0G'<H-44HC="))F2(!D28&2"H<5G/..+:D)5#
@r1580
NATTNANANNCNGANCTGCNCCTTGGCCATTTNNGCTGNCTTNATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAAT
+
""$'%)&*)")!*##%**$!*&("**&(*$!&#+(''$!#!*)(*%!#$!!'++)#%#%$#%&$(#&(#')!%!*$$'$!
@r1581
CCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCNGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACCTGGCTTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCT
+
=6>0";F:63E&+%)8"6C'5D1"'7D(:@-DF,"$2<!6:D*&34;:B>.+:)#=+$*4A5()D>B2!'0C%!$?3F,;6+8'4#@E$%72/1!,D7@%@.>GB?1HC55732%-!9=A6HE2AF08HG&*26/C*E5"D*1??C72H,*C*(15%B3-$5*6>(*B6E.#;?4C7H=E"*7?CDD'A%($3/5G$=FGB*<C'!;--H)%(;657E5$'*E::F5C-3>@1,1"GH.5$2/2E5@&FH>C6G.4@H)H@5;*HB,$!9>!2=>.
@r1582
ACAAAAAAGACCTGCTTATCTCGGNGGGCGATTTNGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATNAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTNATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGCCGAATACGANTTTGGA
+
#("+)!$**"*!+(+%!%(&)!(!$*+&#'(!*#+!'##$"&"+'$*#("$*(+'+!("'+%#%+$$"''+'$'($$+)#&)*+&)(!"!!''("$&#!#!)&%)!&!%"(((""($")$!$%%&)$'&&#(!+("+$%$**"'(&!#&'#&*+#+')+)&))(+&$)*&"'#&"+&#"!%"(#%#!)#"$$)%$+($%&$&')$%)(#*#")#+$(%!"*"*$(#(#$&)$&&!$('+%++!$)&""%#$#+#+%+!+*#"')(&()+(%($+#&$'""*&')$%%!"'**'$$'*)+)#')&'(+)%""##+*##"#!"$+((!++#++))"#
@r1583
NGCATGATTGCCACGGATGGCACCATATTAACGGCATGATATTGACTTATNGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTANTTCGCTCGTTGNGGTAGTGAGATGAAACGAGGCGGCGCTTACTACCGCTTCCGCCTAGTTGGTCACTTCGANGTATCGTATGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCGATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACTCTTTCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAG
+
#+(!+''%('!!%))&'$!')#!$!#%!+'%$("+&++)#%+$""*#'(+%+))('('%%+(*+)%"%'**((#$#&(#**&%"$#&(+#"!&%#&&%$"!'$()!$!#)!+#)&%$*$"!'$+'%+$+%#((&+!'#&&*#)&")&#&%$*"($#$!"&'(##*()(+#"&%+!#!%(*#)*""(!!!$$$+'+"(+*'"&()'+*)$+"&)$')'*&+'%!*&()!#("%#"(%"%""&%&%"#!*"(##'$+&(++!&'%))'$"*&%"!&*!!#*$&$##!'#$!&*&&'%''%+!%$!+#+'"
@r1584
CCTANNCAGNNTGGCCCTTNCCTTTACCAGTTTCCNGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACNGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTANGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGNGGCGACGGTTAACGGCANGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCC
+
'(#'&&))&#''+#"(&!#'$#(%%'!$$$(%&)(('+"$)(+%'#($")"&'%!*+&)%"$%$((+'"(""')%!+'!(($*%"%%$%%"*%(!'$"+%&'&"%$&&#&)()&)*%%)+!%$*'%$*%)$%"!#'#(+$""'$''*!$"+#*$&**!*++*')'&#&)(&"!)#*!%)!(#!+##%+'&!**+%)"&*(#(*$$%'$+$#'*%+&&)!&'*%'$!%+#(#&**'!!%$*#'+)%&)$$%!$*)(#*+!"$)$'!)&!*+#!#*#%*(*&%%$&"%$'#"+$!+!%)#%$#&%'(++"*+!$$)(+&$)'+"(+%!#$!$!()#&"
@r1585
AACAATGGAAGTAAACAAAAAGCAGCTGGCTGGCATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGC
+
G*&$!-DD>C#-/G(6@/0;79B-?:7@?1?3'#!@7B7/G&#-.1H*%,<54H?%;290"A?6!GE3:&61+DAF.D$84H=DG*0A%:G"1%A676>6214>>32#%!<C&52H1(>,"E.0<:=C7>9+(@AG?6
@r1586
CNGGGCGGGTAAGATGAGCACGAACCTNGTTTTTACGGAGTGTCGNCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATNACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACA
+
!!*"*$(**)+('%++((!))(#''!('&(!&!)#&*&*##*+"("*%'"%($*#$*+($+('#$$$$#&)%+%$!'*('!"+%*#"'#+(+)$*$)"++'&"!'&+"%&*#)"$&%'+()%#'+!&$'+(&+)(+&#)(+'+$%")")"#!%$*##("$"%*!(%'&*"&(%)"*+%$)!"""%+)&$'!)+!)*)"*"'!%*!)!%
@r1587
CTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATGAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTACCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATNTGCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGATTGGAGGAATTGATT
+
/.AD1;70.2074C+8FA;'#67"8?D1/36<"AD&A>:FG5A0/%7((><"7&#!B/F#H;/8?@!B=C)<=.A,-+H#504&3*:"B#(H26H,(8=&&DB(?$,<G*5*'"3?C))2("G=<3)#;H2*,;G69%GC7*!%F3&*C33"8)>4(06AE=%@=09?7H+75<35:<D>-!/4?)*/5>/!>9!E69F=.?3+"3D!E-$::*D%A<!.'7HDD()))"G>G,D92?E77#+44D%*!''B.>A*!$>7$-2B"B3<100.#0B01D=>*)B*H@+?F7G;.<D>$A#1B3*C>BC,19=$@#A>67HE<$B7(1/)*;68@>03F+.35H9D=@?1$1;&#G1D(&G2&G.+!4/EG=9E&D!4B99.20&D#G""7#==(>AA1
@r1588
CTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCNGGCAGAATTTTCTGCCGCCGTTGCCGCGGAAGCTGCACGACCGGNACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGC
+
1@"'-><@EG72;7DF-G3'?-0DC@5047(;&1->=H/!$'9=-;,=C=(>;9H*)(#--$/@$C%6/%=48*28A2%;(27%DCBECAAD@@(D51>$*0#&/7F-!3:$7)D>56,;6,C#/9@=5":E/D2&<"8&8@77+CB3;;72<B6;'A7>,%"4"!+F3)199;,B;4A8H#1D6D'H3)!2GB:,HA</<*67@$@!-9;1(8"F;.%##!(*1*H"%E:F8<%D:-:".:)C,-9%-$))#,?E>!G!A.9&G"!E,&)-5=-CH=$F1;*.'%1/DG?,GGC'0*79%*3AE
@r1589
TAGCGAGATTACAAAGTTACCTGTCAAACGGTGNAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGTGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGA
+
-<,#C=2D><#3640B'?&A(3FD6B70C$!,-BF5;#)0E9>!"6>*H!2&7>/=:>$*B@;!HA;35E)<97=?/=88!G3FH18@)G'A-%!8?;%8A+/5=(D/78=DE="H0&>F(4C/9-*5A$B0*F2"<C
@r1590
AGGAAGTTTAGCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTNATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTCACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTNTTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTA
+
G>(;EG0/=3/?(050H79H:AC1G9-G8G,;-?"&&4.4":/",2$92F)#5BD'CH=6+7C!F6E0,>=$D17C>@G23CF,:<G0*A=AF&G=1:!A79H9'2"E(BA=-G;F'@(<-F<3!)-GA/3)3<27?,,!CDB$EEB0D%//6E&=">-E:$HH)++)&=AB0:74;!=;(,/'1**/'*9<25&C,6/B41#'G25"9<;.(>*@!.2@DD@AC+:2+<F/><>)D!@>EA8F3E?$B<4.4-(A;5!&7HD5)B42!E7>E)#7!$<$'B*+E4H7:C3+>;*5%0H;%/;&#9B0B",<A;>,-$56('H'5H"+4E5/@EB6CHGF9#E'6-6:B!:C+@AA-&-C+D9)-/-!1*/3)&8)@7H9345-!:F%;$AD:$3-/:BGG.E)(2:$EB9D<(*$'B(G$.5B7A.')E++0GG3!D7$D7F$5"$6=D(F?EE17F?2#:0.*)7>6G>%7)F((#7;6?E8>D*E=B<:D=-8E#B=D@.;);
@r1591
ATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTNGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCAGCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGC
+
*3!<(;7(#A.A.A'/"5/=:":)$.>H67G?(/7+6%+H5!$-G=(-="%%/"6#/7+CHF*().D8G+D4?F4>90<HG1"/$58?,@377%G$,:49=/>0>79F?4(;@@A6",3@6<%?);>A-=45@*D='.387+>!.>";C**HG1*A:0=-.2"5E!,614*H:&+-,!40>H8:$%6?$$7?-GBB13>5*F&+3G/25.749%(;%%9C!,G.@,+=452C3H=8=(0;9(:2$;D4<;7:>08E.7;9.H+2=E;E)F@,C,F48:D
@r1592
TTTGGCGTTATGCACCTGACAGAGCCAAAATAACAAATGNCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTAATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTG
+
-08C?H37G@A?=0@)$+>:%HD1>1)+D!#.);9(6G1G%7:40-G9'2.F3=97&("4.+EH(9*+2#.(%?5(&B5A2'H7B7,.;+46@D="B&H9#A'7)D(&%%GFG:8@+)H.;A#;8H3*-3<)(:A("6F???")%E<4.*H)5?C67#:@7E;CF'E6G:<4G2+1?.4"+C;!/G+'!#:H)/H>*9F;D<:BD54@2%AC7,7,78.22"D4@F"F3F),=-&<AD?!#'"H&B=&DD6$AF#!,''+/+$%+4F=EG!=1D"(B=/$8#.F5"%A-4?@
@r1593
CTNATTNNGCNATGTNCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACNGAGTTATCGAAGCGGAG
+
&"#$()%!(%!)+''%!')%"'#&($#($(#++$)*$&!&&*&%""()*'*$''##"'#!(''&$#"#+%!$'+&')(!)&&$''%!&!**!+$'!('#&#&$$*%$!+(#(+%%#"%+'!"'%&&+()""!"*+++*($$"(#%!$')!')&"$+'#*$&%(*$"!#%"#%"(##)&)&%#&(%$''+'!)&'%#%)'#'"*+#"!(*'#!!!&*#(#'*)%##")"$'#!*'&'&##"&#"+)**#"%''"$("#
@r1594
GTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTC
+
).*6>$8>:496'?8/!E26DCF-+A/=&63>E'D$BH1+&,*F085EA;!"*4-H?";)'9H?/"-<!+,%9B:!.
@r1595
GCTNAGCNTTCCCACGACNCGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCNTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAA
+
)%'$$'()#&!*"(%*"'+&&"'%*'+%"(+"&#+'$"$!$)!$+(("&)$()!$!!#)&)&)$)+)&#+!*&)&%"+%*"*!()$$%%$$+))*"!)*#))'*")&%((+'+&%)$($+%#%"!""&&"#(##)#"!!$()+%#+('$*"()
@r1596
CGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCNGACGATATGATCCTGATGAAGCTGGATGGCGTTGGCGGCNTNGCNGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGGTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCAGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCAC
+
A-.-0?2(<#;CG#26)0.!5@/<!D7F;<0%/)5%+'9?&$=:%::B"D)@0$H6G.%G',B(340HA6%%?A#'435>0!5)+51;('977H"?"!;,33D"=6@5A+8'/B)C?@G519'+C%/C*/%C&)(8A1?8E&92BD15*2+C)320"EB-.-F@=$(63-.3=<'>35"&A-G<.D>6B!6?=+="-+6:HA8F0!$;"9=8)$>.DD=5"E/.E*2(7F.%-'&G8F@$*(;+0&C&<8&."%>4H(,(@(&">$,5<#'*:+C):,+%5&"!8)/5:94E&C-#F@!-"H>A*9.,6&D(*1"2"6+2@8B!8'0?.;'E.5+2)C2A6$9=&.!A<@8*%#.7D2!>7)/>HH/+$58)#D?#(&#*3.A<:88B587B0A+/:0D@,&?(8$;!"":H'.>58.%D2:66119?6F*:#86B&E+C2CEC5;FH+195B!;,>.2!*(1";3E16G62+0=)#6@#H@$<AF8!#
@r1597
CCGATGGTTNATANGGTTNTGGGTGCATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCAATTGCCAGGCTTAAATGAGTCNGTNTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTNCGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCA
+
(%#%($*'&"$*$%'"&%"#+(#$"%(($$&&)"**')$((#*!&%")'$++%(+')+#!")#"*+"#'$%#"!+*'"()&+'*++")("+#$*+"))+#!#&$(%!+&#$'*'(%$)$")'+$#+*)&()")$(&#""%!+&'*%"*($*#")&%+*%%(!+$"!)!$(%"(#!($$&!*)%""'!'%'")!+($'"!$)$'%+)"!"&(+*"$)#'#(!$)'$!+'%('!$*$'!*+&&(+#!%$*""&!!#!++)&(%&"#%"*(&*))$)"%''+)'"$!()%*'%%(%&'&
@r1598
GTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTC
+
2+=49<CEH>"+'E1F>6!:!E4%(25=+A.@#66/7(F$F?FH*$FE"&/D(/*">.";(*!+!A>AH"70$E&"-,?1("=.'5A>F>9H,$2#6HF)DC'-#(?.&3&1
@r1599
AGTGCGGCAAAGNCAGCAACGGCAATACACACATTACGCATCGTTCA
+
39-773/6=>/"+;@CE2G<D..A=2!7":,95(20A#;4'?*!/;<
@r1600
ATCTTCCGCACTCNTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCNTGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGCATGT
+
,<#:&D>F3=)82#.<#>?:2*,?&<@;%3$D:FE?&-B1:(F%H63*>8:*.*FHE@+8HDC-2&53%%1'*4'4EB'',AB>,GH'F6=2'@94!H$,E+8/8:%9(1B)8H;G0,F/-)5G0),;#%2%">A0*7+
@r1601
TTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTANTCATACTCACTTGTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCNATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCNTACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTNTTGACTATTTTACCTCTGGCGGTGATAATGGTNGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGNTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTA
+
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
@r1602
TTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATNTATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTNTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTNCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCNCTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTNAACTGGTTTTGCGCTNACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTC
+
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
@r1603
TTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGNATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACGGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGG
+
9<9*#?FA6ECB01&G42&34F3-42=(%7G,.'-AAB-9G<3(D'@%14E,E(#E0/5FH/0"D6+/F@32=)!=G+G;F'AA0!8?"=!.-5?B,A<G01+AC5%-55:6BDBA&D@877*</3#:&:-@9D;G1,=E(0&CH%8#)@1""(24@F<"52!@;-6FE:>+G0?A%<GD5B/%>=E.:+#G0"$<G<D5::F(</8C%F@FBE<E*=69,50324D&&(*@0'<!2AE0-,F@$9B#&'1@@021/0!-'E0AB#$7E'#=)/06%"C;F/#.CB9A:'F/AH4:4"F+3(5;%=D1$!<;62D#=1)C;'+2.F07(=%A.(6.(+2+6+-
@r1604
TTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGATATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCNTTGCTTGTGNATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGNCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGNTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGNGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCT
+
)4+/D-C>*)!8>3;B$.<A+"'%05*?3A%$$=6B23/0EDA4261>'(,'*#3:4EG@B.*<&#@90=8#EH<"(A52A;5+-8A3'@><G>A#.2(5F#7<-,8<A7!!7,82/$=!B!99?1#84/E-5/$&9>F34(D?+%"3-B@9A<-;,@(*7*,,6F?$'FF$F),G$.#H-0;76<0B!*-G,=H.F+9$=?B";H;>.E3:ED2.CE-)?7+78*(37??4&0;@!0"!HD5"72D5#?/<4#E@#=G(+#$?*6>,0#!%$:26A+&2C69"5)<-6,4F!(*7>BE8'E%$@+#:!$$")B;.B>(@:.75<!+/2;.2C?@9)/C2?G+"(F3D>5':.2E<AF.84EH0F99D)'";;;485)E:0=?'57@;HBF4A6H>CE-H7'+5G1#$,99:"DA,90.?/F769>,AF1!)0"6/4%68+!'4!+;
@r1605
CTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCGNCACCACCGAGCACCATAGTGGCGCCGAGAGAA
+
=*)>E)0G6=<3>'G!A:C$B2%%0+-HD2="/=H86!1)(A%2G:4'A@G?C0AGC2"(GB0%B''D!#35F18.A/9E:07%7>/A(,="76$*;5>+'BG$1EF01;+A=>$#*/1@>1"1G%@2'>8B)C2D
@r1606
CNTTCAGAGCAGCCGGACCTCTCTGCCCGTTCGTGCCGTCTTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAT
+
'$<4$A3=/<C&1H*G:;C>31&>DD9(-A7?-G!/(2>D%86-G&%=E:"'8+.*>?<&+0=9G#*7/&(3B%'A58%B.5&1&4>>+DGG0)=1)$;9325E1"07--B>D;'%.42):$-49>-<6,$<0,5H7"9";
@r1607
GTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATG
+
1?-*/*.(/+.9)B4?#6$H.>222A?D-<C@'!<)3!1A)B;<
@r1608
TGGNAGATAAGCCTAAAAANATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACA
+
5?6054:58#*@=/%7%%?.((D8'!,!#0%DD$D,5@73&F;799,9,)99/#;79+','.+>2B9:>)E58)(F<G40);=4:!2!,;5/;(2"
@r1609
TTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTANTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGNCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATTATCTGCTGGCCGGAACTAACGAATTTATTNGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGNTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGA
+
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
@r1610
GTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATNCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCNTTGCCGCACTAGC
+
=B'-0B:+=E/GB?90>G1G,F>D:>F%<D,=.E26DE(B&DH:(%&./$=;0*'F90,-GF$74#B:-*D1=;-4*#!',-F(?HF=0=)E;18G@%$;AF-@??/='@44)(<&4*91GHH%GC5"+?'$8!>/*#G280/2#+F8/+C+5#3G<&5(7:%E8)6.D7")0*@=1@F88H7A%D2F(=7G%3G=2,5%,10F&"=2*2;%/*.98G>'">4;'<!.>4-.&3E0@$%5F@A:85-A!#@7*6%A&#-F22&)4C$)G&D00('4:&/),#!5(E@,7:80C"'2/.D3130?5)?;&$6
@r1611
GTTCTTAACTCAACAGAAGATGCTTTGTGCATACNGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGACTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGC
+
>BC+)&,07/4%F.>6B,@4/>5B+F(7)(9'2F:883;,2=/0FA?D2:C0$'?/158#B)>,8A:H22B3%:("E)>E,*C1@<5*H"0(D2E4B:.'28='FFH;2;32F*13<*!45!$4ED&4:-<'./*8#1";F$7'B.'=FC;@C3+;5G>5',-83D/@/9F''9$4@7>H5D>=CB'D-D6;6H5@C":H@*DEE<(,&1%%"=-A9:>,)3-?B.BC&77C?F7*GF3-;H+//="8B<.625#G
@r1612
NACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGNCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGNGGANAGGGAAGCCATGAAACAACTAACCTTTGAAATTCGATNTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGGAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGNGCCTGCTTAGGTTACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTNAAGCAGCAGGANGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGANGCGTNTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGAGGCAGGACTTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGANGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGNATATACCGCTCACCGTATNGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTAGACGGTATGGGAACCAANGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATGTATCGATNTGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTNCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACNGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATNTGCAANTACCGGAACATCTCGGTAACTGCATATTCTGCATNAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGAGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATNGTACGAGCTAAAAGATTC
+
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
@r1613
GNCGTNTNNANCGGTCNNGCTNTCGCGGATGAATATGANCAGCCAACGTCCGANATCANGAAGGATAAATGCAGCAAATGCCTGACCGGTTGTAAGTTCCACAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGC
+
!%!&&#$%#)$&(&(&&#(('!&+!+(***$$'"(+%'")#!&!(&"%%%$&((+&$&%(+#("$#))&+$&#)'&")%&*+(''"*$$&+)'&&*$!"!*$%(*%'(*$'$""(")"*#+$$$&')#'"+"#"*"(*$!*)+('++*%)')&+*$(+!#"("(+(&$*+)*%)'+("+(%++'$+)'*%
@r1614
CCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGANCGGGNATCGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGNCAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTNTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTNCATAAATAGCGAAAACCCGCGAGGTCGCCTCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAA
+
@"4A&E2GE%$:F&4>2&#0.?6-*&B23GDB7H;!36=@8B.8*$9B7;E*6@-E8E?-2C"3@&+@241*)A9"07E28-"$/*56&02!(%F18BG09,E!E#F&7C)&96DCH+?G35/B8E>3(@?H3$1!&,:'D/9>.-+"!C7'"@*14+37:-:78"%(5)F>,&1D(A3FB9H"*7+8A1;F'<=<E&"3?+9&!%'30:%G.:%AG#"!!=168,;-,B;<3!=;#H'25!@"#"7-'<86(H)<1"A('"&0)),B/C+,B4+-C4$@&:80E(".+6286?7:-5)!E5''$>,DG(!71!%(.<:+8549$,9EE=%56,E6'=*?6,<1:);8)CA&CCG76"'=F>'2@FD4'F0"A-$7&>'G)'@2),3(&?85%&&A,B!8/&B!-,'6'3@8%?C&-++C67?)C0-0/
@r1615
ACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCTTCCCCGGTCANCACTGTGCTGCNCTTTTTCGACGCGGCGACCCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATNNCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCT
+
,A96143A.;<976G&9?(B-$/G=!@@0FH9=?522F756G&0)3&CC:F"(4(,BD,/"91A.H'@5,$E8/2@A'G@%6;)7?C-&F)<7+6<A(B)?63$?*/&=7..3(?&9HDC-D*55+4E!?(/@BH#9=#=#24"@""0%6F!G(%H68/"#(F>89FH8/D7+C(CB,+.($;?.3,!E%,B&GH:=D=$HA<0#?'=7$B!$4B6+)16;G/$FH%4(53&&7E@2B-
@r1616
NGNNCTTNCGCNCNNCCNNNANGNNNNNNGCNCNNNCNTNNCAGNNGGNTCNNTCNGNAAGAANNGATNCGGCNGNTTCNNCGNNCNTCCGANCNACNANGAANCNNCCCGCTNNNNCNTTCNGGNNNNCNNNNGNGNCNNANTGANTNNCANNGCGNGNCNGNNGAGCCTNCNTNTANTGCGNCGNTGANNNGNNCGTGNNNNNGTNCCGGNNNNNCTANNNNATNNGNTGNNAGNCTANGGGNAANATTNNNNTGNNANCGAGNNAATTCGTNNGNNNNCCNGGNCNGNTANNNGNCNANNTNNNCTNNCGANNNNNGNNGCCTNGNCCNNATNNNTGCNNATNAATGNANNNNNNATNGCNCNNGNTANNAGANTGCNNCTTANNNAGCGCANNCNCNNNTTCNCNCNNNNCCNGNNNCTCTCNNNNAANCCNNGNNGTANNCNTNTCTNGGNCNCNNANNTNNNGNCGNNGCNNNNANGTGCNNGNNCAGNNTGNATTCANCAANCNNATCNGNNNNGNAGTGCNTGANTNANNNGNTCCNNTGNNCTATNCNGNANNNCNTACCGNANGGNNNNCNNNTANNCCNNNTANAGNTNNCNGCAGNNNCGCNGGNAGTNNCNCNNNANNNNANAGTCCGGNTNGTNNATTCNCGCCANANNNTNANTAACCNCGANNAATANATCNCAGTNCGNNGNTCNGAANNCANNNNGCCNCNNCNNNNGANTCANCNCNCNNTGGNANNNTNGNANGNNCNCNTNTNNGNCGCGNNNCNANNNCNANNCNGNCNGCNCCTNNNGCCTNCNNACGNNCNCATNGNGNGAGNNTANTCNCNCCGACTNTNNCTGNCCNGNNGNCACNCNTCCNNCCTGNCGANNNANCTNCNNNNANGNCGNTNNNCTNCGANNNNNNTTGNANNNNNNCNNTAGANATNNANTNANANGANANGANNTTGNNGNTCCNNCNTNTTTNNCACCANGNNGNACTGCNGTNCTGNNNCNNANNNNCCNTNNCNNGNAAGNANNGGTGNTTNTNTGTGNNNCANTNNTTTNCNTNNNNAGATCNNNTAGCGNNGNNGANNCGCNANAANTTGNCGTCNNTATTNCGNNANANGNANCNGNANNNTCNATTGANNNAGTGTTNCNGNTATNTNNNNGACTTTGGNAANTCNNANNANCNNGTCACNNNCCNCNCGGGNNACGCGNANNCGNGANGNCGNNNCGNCNNGNCAAANNCGAN
+
!"###"#!""#!#!""$#$!$!#!!!$"$!""!##"#!#$!"!$!#$"#$#!"##!"$$#!$$!!#$$"#$$$!"###"#"#!"#$"#$!##!""$""!!""""""$$#!!$"$!!"!#"#$!$"!$#""##"#!$"!$"$!!$$#!##"#$"!$#!#$$"!##"#!$$!#!$#"##$#"#"!!#$##!"""$$!#$$$!$###!$""$"!#""!$#!!#"""!"!#"#"#!"#$$!$!#!$!#"$!"!$"$"#"$"!!""!!!""""!#!"##$!!"#$!""!!$##"$!!!!!""!"!!$"$#!#$!#"#$$!!##!$!#$#!!!#!"$$$#!$##$!""$!#!!#"$!"!#"$!#!!!"$#""$"#$$$!!#"!"!""$$"$$!!"""#$##!"$!!!#"#$$""!!""""#$$#"!$#"$"##!#""#""$$"#""$$""$"$#"$!!#$""$$!#$!"""##$#!""#!$##"$"$$!$!$!!#$!!$$!$!$$"$$!#!""$!#"!###$!"$!$#!##!$$"!##!#"##"#""!#"$#$"#"!#$$!"!!#"##!"$$$$$!$##$"!"!!#!!#"!$"$"$#$#!"!#!$!!#!""#$!#$$#$!!$#"$$!##!#!!$!#$!!$#$#$"#""""!"$$""!##"$"#$$##"#$$$#$!$"$"#""#$!!#$!"##!!$$##!###""!$##$!!""$#""#"##$#"$$$!$$!$#!!"#$#"$#$!!!#"!#"##$$""##!$!$!#!$#"!$!"$"!"""!!!!""""$$$!#$""$$!$"#"$!"###$"#!"#!!##"$"$$#!!$###"#!"!#!#$"$""##"$!"!##$$$!!""!!!$"#$#!$!!!#"!$$"$"!!#""!!"$$!$#$"!#"$##$$$"#$"$#$#!#!$"$#!!$!""#""!!#!$!$#$##$!!$!$!##"#""!#!$!#!#$!$!!!$$"###!$!!$!!$!$"!$"!"$"!"$#""!""$$###!!#$"##!#$$##!$!#!!#$#$$!##!##$$"$"#""#!"#"!"#$""!!##$!"!##"$"$""$!"!""$$"###$#"!"#!#!#!"$$"""##$$$"#"#$$#"$"!!!$"!##$$!$!""""!"$$!!$!#!!#!##$!!"##$#$#!"!#!#!#"$$$$#$$!#$!$$!##""!$#$""#"$$"$#"#"!"#$""$#$!""$$#!"!"#$$$#!$""$####$"""!#"!$"#!#$!
@r1617
GGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGTCGACGGAAACGNATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCNGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCG
+
/5/%E(2GA91,$HF.74;-5GA;G&:0<C)H)4<>,H/"D,+1%E4<E$!,5"93A'31)1;)-!H*?:;4;1=!!DADF<.7"D:,3":/10%@)-G=#A#BG.C6C%1DC530%.CE9G%6D>HA34F:F(G4;H6#)/E651E@6=</$0)$;,$-1''CC14=B2<,FF83)910A=81'A4/24/''0=F(=@&33!:-!*B#3D>#).(:8<-':/),(G(!56*F-A:%2.(#=BD26=DC545'+E9?<:%1>:D=6-.GH6'"8'(B+4<1/139;?1:<>7."F,&)!"F+3.)E(3=<H:C->62;40B>>.FB6.0C.#F9DF24)8+A%E'/+&3=(#C@=.6&B0.#8CB#"8+@3"%D<?&.+0/C5$7*F,!+"*<<)%)'7"<#+(B>-!4*/'728<:@($A2@6)=&'8B.F8/<4),;0H#/@
@r1618
GCCTTTGGCTNTACCAGCCGGGGGCAGGCACACCGCGGCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCNGACCGTGGATTTCAGCGTCGGCGCAGAAG
+
0!/F8;"'7+=94=#$$?/#C$&4A<7(C4.(>91F<1-H:2(4"6+!>E'D82)D7./F=E'B-BG:'5'%'#4>04*$/$,/33HG1'>'$&66=>5231>70<
@r1619
TCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAA
+
35.175+/E1:E%03C<@5<&;/@<+'H5/?@4<8?3/7!A6*.'&3E$-78.2"7,>#/,(,9E"GGF4G?+%,)5$92FHB1(//,;7548H7%-+'-771>F(=D6'+G9F;49"3&D8;0F96%?@8-"34DD9,58A8#6,G5@<(B8D2)/3@7C+86H3544C)<"+47;&6+B.",E*.@?'-A;;!FA+/87$F5"(42AFE)<3F'9F7<3$/5>;,'8806?"@&D5?2=EB$1&8)FD'@.$#>$2=)H>&/>'D-)E(+D=518:<//DE5-+C9+)3(1;03D>C9?0;2"(4F46<2)5D=/HB-*991HH?GADA=H0)<96!%F/8F+EGFFAF15&"9@780)H#.#&9,8+-6(9G)#*$2ACA:"6).$E6(>
@r1620
TGCNTACNAAGNNGAGGNCGGANTGNNGCGTNTTNTGANTGNGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCANGCCCTGTATCAGGACATGGTACGAGCTAAAAGATNCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAANCGGCANGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAAACAACCTTACTGGAATCNATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGAC
+
*#("&#'!'%*')%$%#%()&'!))($'&$"$&$!'!($(%"%+!*&&#%%)+!)'+'$(%'"'$(&$)$'%*#((*%(''&)(##))*)+&#&!'"'+%&&!%#'!%+$)&)&'&%#"')'$'$!"*(''%+!+%"*&'%!#&"!(')"%(**$"$$!$$&)!%!(*$$"'&*+'+###'*$%"(+%!()!*&#+"%#!)!(##'"%++)&()&('**"$'"&'+"&"!()$)!+$#+!+'#%+"$!*'!+!+!&#**(!%&+(&$%(&)!*"+)+%$&*%#('(+(*#+!%")+#'(!&!!+)+)*#%%$"&(%%))!##")$#(&$"'#(%%*##*'+"$!)#$")%)#*)'++"*)'$$*+'+%#''"*)&!%#%'*#"*"&)++$*"%$++**$&!&*&#!!%*&$#(')!'*)
@r1621
ACAGTCAGGTTAACAGGCTGCGNCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATT
+
2D:;BF=@/*D5=:.-G+4?E=2CFD0&6':-:=/.CF#9=*8'#>?2+(-?>E!8?G<@)*"07.(-*1<!#&H)H045=(!=8")C0=#F*8:19("
@r1622
TCCACGCTAAATNATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAATCCCTGTGTGCATCGGTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATNCATCGCACCNGACATACATTAATAAATATTAACAATATTAAATNTCAACTCATTGTTTAGGGTTTGTTNAATTTTCTACACATACNATTCTGCGAACTTCAAAAAGCATCGGGNATAACACCATGAAAAAAATNCTACTCGCTACTGCGCTGGCCNTGCNTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCNCCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCNANATTTGTGGCGGCGCAGAAAATNTTGTTAAAANAGAAANCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATNGGCAACTTTATCTGCACTGCTCATTGATATACTTCTGGGTTCCTTNCAGTTGTTTTTGCATAGTGATCANCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTNCCAGTCGGGGGGAGGCTGCATTATCCACGCNGGAGGCGGTGGTGGCNTCACGCACTGACTGACAGACTGCTTTG
+
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
@r1623
GAAACATGATATAAATATCAATATATTAAATTAGATNTNGCATAAAAAACAGACTACATNATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTANTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGGGCAAGGTGNTTTTTGTCTTCTTG
+
D,0')9GH95%((?:=74=G?G,#.5C"F(!=(@5&C6=,#1-7E*6'!C7#9$@7+.0.)BB:E=(=0BC991*AB7A-,1@;'1+60C#!8!5:0%!*%,/A"A*@,4H:9?=(@5E,A*219H,(9D;*!";A#<4!)A6GF9"8D81#9B$8?(=?:2
@r1624
ATTCCNCGNNNCTGACATACATTANTAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTC
+
*'%*"$"*"(&+'"+)'$""!*'+$!'$'+(#%!#*!!+)$%$#$"%""$!()'#*!$'&)!)$!")(##'$&%''"!+
@r1625
GTGNTTTNNGCATTNNCAGANTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATG
+
(($!'%(%"&(&$$"*&)*%&+()(+#&("%!'"+&$$&#%&"')*!*(+((!&!!&()%#'*#*$+)&!%$(*'!$%##$*#*+#($+#%&'%+*(+"#*&)"%$*+()+%*'"
@r1626
NACCTGCGTAAAACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTNACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTNGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCNGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCCGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGNCCGTGCCTTATCAGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAG
+
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
@r1627
CGCATCTGTTTCTGAATTTCNTCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAACCACCACATGGTTATTCTGCTCAAACGTCCCGGACGACTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCAGCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTTGTTGCCTCCNTCGT
+
+<1=G"05/#?+57:-("!<@6$19#53AE@;9!5#:13*9GB0%6.E,B,E)?HF>0!#*@3D8G*9.2*/12?1C37'D@*82>/=#@D(G$:D@9>6<$#BC@4-+'$>A48$(FA**,&'H!A=(3-)C<0";6.1<)!/>=*023!#*(?%!H>0"(,4G?40<A.*7<+<*8-&B285/D$(#BH0447DFA'DD>).E9$.92(GC.=+B-"*1@(-6E#,;6?*.%7?4"(79987.!B"=;F(;<
@r1628
ACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAA
+
?",AE.'804=@"C+!$;:;)13(1$6&<+?7-*=)",F%C98(-C*-<B:);4AC#;A!/0E")-7:&<#
@r1629
GAAGCNTGACACCGGGGCACGTTTTTTNATGGTCGCCCCGCTTTTTTTGNTGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGACG
+
+%'!+''!#)(%"*)$!'%&(!$#$*%*#&*%)+('!")!&'+((#"*+"$&$%'$+)+*$($"&*&"'$%*&+)&"#+**+#&*"(*($%'(*"%)%*&&%*!&*
@r1630
TGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATNGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTACCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACGCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTACGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCNCTTCATTTCGCATNAATCACCAACTC
+
;)65><F0,):C*3'4?6!2?8)5+4%208*0*#+8D$H)''61@E)4F$15G%9!&?C:<*G?03<(3>=&+(8?&4F(?</;<):,A.-@!H=5>?:@:(%&AGF,@2H,4<='7CB138;AD6B+DB,!*499$1D3467*C(G'-@67"9<*G,%4$;DA12-$H@(3%B>FAA>/B#8"#H),*H30.+?>AD$*(;$%?H=,3-<!#D9CH&/<.-#)G0=F<!36C3><//CGF@0$GBD(;F;6$.*@1-D00<).E=.@,C?)=$67()03!EG:#HF48<+7FF514:;-;1HA=+)A%HA+*1&A"4?64)"2F2*H4F./<%?%F75+0?7BF>7AF9:9/7%*8)5(#23,:"6%E3#%A/81AH00/F'E%#1"F#1##'C;AH3>4#!0C08)4!?:<*3/(:&./4#G?.H/%16&;<E@32;)7H69B1>3@2E9*-A7';'<>>B$<?%*4047"!&,2;1%9DE7A>B"A5945:56%GF
@r1631
TGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGG
+
*B$;GHE1B5B.:B=;>(/61+()"/*9$("0235*FD8)>$2>865.@B"%>01,"-@BF!C1%'=EB
@r1632
TTGGGCGGTNGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAANCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTAC
+
F1C->6@)"7*!E1G:>*(3$*F9<?<>#?/-@1C(/#=*H5CG%BF3=8.5!56.52;,/;F0-.)F9$9"%(9D=%0.'4;FC!!(F$+8E>!6H1%*45'1=428%/((!@)C,$BBG7(F.+5.9>.H?3#6D7%<&/$5FBH(='7:36874@=1,1/&)17?&!E9C6-%6)80@/E%G/-@C,8CE>&%5;%2@A3<E?@#3G'@-;@>6F&)@81DDF$7$!&)*;<'/$'(;;B@E2#-$D@8/7G.+)F4F?;+0F>-&+9E;FD-,9,@8"E:%E#:)->#.7/#F!1=F!E*'?A4*"F:>(D4<4;8A-@20G*):+,3<-D50,#7*7E5D$8!F&-0%"639>@694+1;,@!F65>?.-?!?@!)+"?E740.>C44F'7B&"4//>4(D9!FEC&$A:)*1*.G;G<<
@r1633
GGATATCCTGCATCAGTTCACCACCNGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATGTTGCGCAGGTCACCTTTATCTGCCGCCACTCAT
+
9)'>H>F7.D4>DH*D7/E'DCE(7"!>B6BE=5A+%#H>-"@C5=#G@C5A2''2@2?1D#E8"#(#F4FB8<A#-!H)C'6%'=)82H(,!+F,=?59/5B'7B%96,&BD
@r1634
CAGGCTGTGCCGTTCCACTTCTGATATTCCCCTTCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGANGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGATAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCCATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTNCACCAATAAATNCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCNGAATGCCATTATGCAANCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCNCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCA
+
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
@r1635
AACCGTCATCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCCGACAATTGTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGGAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTAGCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAANGAAAAAAACNTTTCAGGGAGTTGACTGAATTNTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTA
+
?&:;A/;8*/,A%@3C4*;"E;FG7;A7?2A-+2/71H"E6*8(2A&#2""=F!;,51D3A0:.9E>2?H.%3;>99!"@/06=E%4B(61.7#2"E4-G7F;1F&;C35E1!%D!-=6,+%-B.';*A'B)3D#@)&-)A8>+G9;%8><$:?&>&='?FFG4&(A*-<(%E%H1*<;<:6C;/DABA!,#->?@F@0'G<A,+%3GH?!?.A2-.@@4F8!*!!-CA#E>9/,=&5&*B!E@2H4!%**"@H*4A1C2BE=4B?>G3::/1;G,04$H7$C)='G(&%,4"-'==HE.4!?!-,(8:3/$=.5-;<B"A!$0;36(B<A9>G<+03=D?5C!2!9.,!6#.D3"BC1D*(
@r1636
GCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGANAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATANAAATATCAATATATTAAATTAGATTTTGAATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTNGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACNAAGCCTCGCAATCCAGTGCNAAGCTNTGTGTGCCACCCAATACGACCTGCATAACCAGT
+
;$$/4$"D.C+0'/$E'<3C<,A:E5C/F0C%,41#E&+7E;B@'*;0*9?1B52:.3,<F..55:A89*8&72)&27@?A/=H45#F"2@1,).)+.+99282#@/:/&9>'8A3*0-95;'?4?:<-HB+"(4.30#69.)G=?0@%F)+<+-G20@G'#?;)?@B1!G'G-D7@;A:FH?=."+!C3!1'0?DHG.<(%2:%3$6B64'$5&!<%2:H',D>5D974*87D>"7A19G;/((-"=D/)@/.44;6<%9(1F-A<826-!!=#5+,H22/82+F747(@>$0H%66FG6/6>:8C6A85F=*4=&4?G/1?%(%)7<6B9,'=>*GG%))*(/)C53!%:G#=6GH+!+A87C415;*A;&.*!A?57!#?4'+@%"15<07&D)*,;F-@83/CG=:A3#.90+@6-++D@HA3=0&CH=A9DG5G6*6F=2*?4.!,#(C
@r1637
GATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTNCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCNCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGTGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCNATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGNAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGANAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGT
+
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
@r1638
GCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGC
+
.7?6#65&/+E4&$:.;34)?D#39;5?&)B.D6D>!%A*E+20#H"!+,1/(;06)!6251$AD)7#=/H')%'8>;A!F9?,4:06"-0+FB#15),<(*,"EC=<$
@r1639
TGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAANCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACGTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTNTCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTGGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAG
+
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
@r1640
TTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTANAAAGTTACCTGTC
+
B>7%C?GGG'F%%.E40'@G"E(56)BB&@".09!:3'718E9*A>;&+/3=?%*%3<:B=(7/15->31F4F1@:;.6!=A8-?$D?HHA"/1@-)('=?=GG7');B+=5F;+12A8+$*<'1/+9#B</A
@r1641
GGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATACCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGNAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATT
+
827/-)C#)227DB;1(H;.9A%$E;<B)'79;.7/81=*C21@"$90?""@')#;6:"5-5?$($#,$GED)C/)H)*A,AA3:F("&G,-7.36E@A-@6.4%HB6G6!*%F%9;F$#0,EF94%#0.:<F?C14&"!2?8;@4.B83309'7)0@1(@D?0F'H96#*H8,*=!7"%(*/4)<2$,6>C&13=E3B%64&)2A1%2<+5<?A%F6*:D@)HD+(+/'@4@&1!*<-GA"D";A;<;4%":5A$9G);7@/.*:1B=7F/>2,H.B>"!-
@r1642
TGGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGNATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCACATGTGCACCGGCACTCACGGCTGTACCGGACAATTAGTGACTGTGGCTGCCCTGACTGTCCGNTTTNGATAAATAANCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAANCTTCCTGTAATGGTTGCTGTTCCATAC
+
56BG,*9C?5,$=;*0=1,*F;4'<@A$'&9D4#DA#%C<E+@@&%,#9"5,./3<;!@F8<B5C%@B<&!%=?81?>&2;A$=0.;E+B#A30G?;E*F=7+,(>:D=590;*"2%5B+!4!;2BG&**93>0F"7@(5@*("*61?&6+E>F>8.F$7#),;486970?F)B:(&<HH.G14A/18H*,4F+F,&<(BH+(==3'3$C)1B8,,G9&581*E79)4(9$"B5*A&A?!2DEFD:)5'*:"CG%.$/3D0D;1@47%5H*)F
@r1643
GCGTTTATAGTTAAAAAAATCTTTCGGCCTGCANGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCGCGGTGTTAGATATTTATCCCTTGCGGTGATAGAATTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTNTGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTGAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGNCGTCA
+
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
@r1644
CGGAGACACCACCGAATCCNGTAAGGTTGATTTGGTCGGAAGCGGTTATCTACTTTGCATTCA
+
?F10#$4707F;6(2=(-&(:5!&DF*A.F"72)$,<&'6=+0?'33E,&G,?%,FE9*C#6<
@r1645
TNCGGGCATCCACGCCAGCGTGAAGCTNGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAA
+
645A*>6>>=G.;'G$3/-(G4/,=&$C>B*3?+DC19B3/A6?6H05!7?+3*?:-)'CH$9"8;&+0$0;99>6?2-F@:+%,F>&5=5!;->B/&5&,5822-H&@!@GE?8H*%>/9F,)3H:6-4<C)=5"1G;:G6*>E($'$+6.C';4/%$2(HF+*?=@+E?=*4@+)2F47B.F6?$!*3/,#$)3!..B)<)H(A-HH9:5
@r1646
ATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAACACTNAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATNGGAGTAAGCGTATTGCTAACNGGAAAGCAACGAAGTCCGTGAAGACGGAAANCAGTTTCTTGTCNTTCGCCATCCTGNGAAGACTCCTCTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGNGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATA
+
0'H(E709)3+9H1(+%7;#1$?.-=49'6!/>$?(03"D6!@53GF8(C5G9G"G;0.,8D11#73%4A:'!8+-+;<B@+#?D6+92D70($0!HGE?"62(68+=2$F1DDG5=(A@##+>3;;93'4*"F:;54@;,&<<351$H."<3.B!-'2-GB3D;5,:7=?<3&),GC%=/!G(>77&&@8*>7-9&G:1*98=&+94686"H;;3;D.5@@/1D$4E*($!?4*CBEDB@C@/6G:B)..6CC,%-+&06"8*H1=7+.=)5@E0**<%8"G9A%<A?H/D6+:<#75@G"?H='9$=:>$-5;1:*.49!*',0;E8#B8C@E2<,,$"E1@A3""!)?:?B6$!/'90.D98(C31#F$7*.=*6@"+H@5)()3
@r1647
TAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCA
+
(6FC,;@8H2@GF9417):+:3D>BA683,6-!;)D#H'4<%A"
@r1648
GCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTTGGCAAACCAAGACAGCTAAAG
+
*+''$+*'''&'+'%)(&+"$'%#+()$*&!'"+())$*&++*)#)&"%%#*#$''"'$&"#('!#+%(+"""+"!##*&&&#*&(%!#*$+%)%)*&(')+))**("!+*!))"#'#$*%&!!$$%)!('#%)))%)(*""(#*"''!#)%#')($**+*($''$!&*'
@r1649
GGCCATGCACGCCTTTAACGTTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGNGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGTAGCAG
+
:6C?D;HDH9D(,:37$&%'68?"*=(!CE&D&*<=6G3@?A)7;=F>)E+2(?@0B/;'&,B*'49F/'8)5+5!1@<$?@2125?)6,:57%$E=99%#+4,,&FF12",G&*?1("D<#7+91)67<F5"@.0*%!&F/:'D?))G5(C2%EH(E*&*3'>7):F0*8$B)3A'B+%!,%.1F)+3**,F23@<!E2C*4H8+1AF0H5F(>G3;A*2+E'%BF5:-F=?E!!H>*.:!"79.8?D%G2@3:D-$&%-0+=0A'#B"5E1"(;8?ED<48>8,<#/!>HC94/HH<;.:;<F?-E*E6:%,/1+6G8F*)D7'<FH.D6)H$#"92,7G552"<,1!E18AF+B03:=:%.?C0=GD2H)!/(#G:$D>BEB?(C.B.6=,$E;A5)!5E;-0'=?@HA;;7B$B150FB@-G$@9+/C$?:C'7*B(100!)0(30415.;+E=<&6.!(84)(G(2#:5'.6C-:-'2/
@r1650
TAAGGGGATGTATNGCGATGTGGCCATCGTCGTGTATTCCGGNCAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATNCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACNGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACNAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGNAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGCAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGNAG
+
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
@r1651
ATACTGAGGCNAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGANGCAAAGGCGTCGGCTATTCAAGGATGCCA
+
0%H"<=A8>1H7>#'B)=<A(H+.?)?BBB>+6E0=*4AG9/GBFD!(%&E0@$9D:/3;')<)@274H"+G=%.'1AG93#EC/.-4882B/)!=>5;>%!,9C>F77:5!>B!D'G.F/),9D:'E&>@/C>(-E"&$F;(46B055/(&G-+*.*>G-43F#:58#A0%6.*7AE,$?CB.3G1$$)'*.%?)9&"2
@r1652
GAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACNGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCANGTATCNCCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTCCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATNAGCCACAGCGCCTCCCGTTATTGCATTCGGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACA
+
GA9--0D(10HED0D>1/?<7,F)=F=%)1:*>7>67G,2"DEG&48D.=+83?=>@+"7)/&>9$6#*9C$H<F/1@*6'"F./>E!G%34B2-/0&@<?HH24DF2B7;$:!61C8+792?(<%42=(6B,F?1E"437&7E&+'6/9*C!E$:(9)?,7;D;49"3E&0*+F6D8$D*+GF'7-<8E+'@'-F-'!.3"1FB('03*H<-"3(%49;B#8-1.?:F@D9=<<-*'5#=7-4,&@6?&@EC#DB!3EC-"'H"98.EE/&D@3"2$98#6EA"H*;8A6'8'H=GH/E>/@2'F=@/;@G=07C"3&=@!G&G4(7D2@);-C#7F*F#'*A-?0!E<?B5@56C,/="$F&5608$&=&BBC9D
@r1653
TCCTTAAAGACGCNGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGT
+
E-2/7;87?*@#B291&E#<#"@2$-@E,$E%@/'!1E13C-0?8="8(:6>BB4C:>6F'A65/E04)@0F*'!;$G!*8%C25?@$$#,D%
@r1654
TACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGNCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCCGAATATCAATGAAGGATACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACNGAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCT
+
HHDA><*-',F&:1#:@4/%@CF8E3A-<->8'/76E3F>@!@#%'((*.5B"+@$:0B/72%.G4*0"E,5%/=DCH?6&$4+"1<H)%6+F3HA+-5DE6!?5&4"(AA+@1##&91#H8=-&8E()C%&<0;A(D-5;9*6(0C5:">B</?#C7,28(.81/@A">.A-+,=+9(CHBD2#*;9?B)3=DG#6%6"(HEHH#AB&(;!(#?/8E8269CG39-)C,&*?"F,A<H40'*D<',7(--(-=2#97@#".95+!&#)D+G/@"*31+,2:$=<2/
@r1655
CTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTCAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTANCTACGAGAACGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCGGTGAAACGATGGAGCGCCGTGCAGCCGGTNTTAAACCGCCCGCCTGGGNGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAANAGAGGACGAGAAGAGTGACAGCAGAGCTGCGTACTCNCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTATTCTTTTGTGCGCTTGCAGGCTAGCTTGGGATAAGCAGCCTGACGGATGCGGTGTCCGGNGACAGCCTGNCTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCNGGCACGCTGGTCAGCCGGACG
+
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
@r1656
TTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACNTCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCNCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGNNATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGNATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCNCGCAGTCATATGGACAAGCTCNTCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGNTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCNGGCAATANTC
+
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
@r1657
CCGGCCTGAACAGTGNGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAA
+
9&A963+A:?1!?//=$)<8+!A%BA<B:,;;*E@!F456%&.%<EC@3EC$@C"/?<E8,?CC"&@=>"@,.:&9D44"(';E-C?H,(?.?@@9%/G"<7F,:/3/B61*%EG+.3$1H&H=F6)B%96""B(-G?8;5F"D(<2$?"
@r1658
TCTGNTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTCACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAANATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGTAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTAT
+
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
@r1659
TAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGCGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCANTGGCGACTGGCGTACTGACGGATTCATCGT
+
,$ED:.?D$*F'$+F':4/-305#E=&0)<+;58'6E?@*21185$&;F*HH3>$1;FD#7A8F$:,6C/!&EB->/G6B6%94977BF$1&"B"6!4%43'H9<1<G/!.('#;.==-EF88'"3"A5/(*=923<GE-8*0&F-3A%B5,C#;5=$04A0;%A(63=91;,$E3><D:*(C$G</*;39)#2=6A99?CD20,DE&#D@E97:1'-!>A'-@1!6G84+"$*.+D=&EE+9"=8?$E.5%A@%
@r1660
NAATGTGGCAGATCTCGATGATGGTTACGCCAGACTAACAAATA
+
&*+""&%&##%(#")"")"!#''!!($$#%"!$*!"*"#$)'&"
@r1661
TCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGNACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCA
+
+/2BF8F$&29G858#.&C/'A;'683CEG0"5E+!'!';25%"$'+?6CE5G<EAD#976."B"2<3$7(*?;0:89D.G-9$2$*##1:A?:-C1!B4,*578).3G'59*.!:@$
@r1662
ATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATGGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTCACCGGCTG
+
E-DG,:$'C+.--7)/E1($-H(-;%(H(5,23/..C,%9413+/4&?6C=EDEG>C'?H@1%=,$)<#5"3B>=A@*EH"C?!+'6$<4/&;A<11<.6F>$8<B,8G6#4F2$B66?>F1#>D57GD1E-H/!C2>6D20+5%;9#!F1!&7H309*!%<!1351
@r1663
TAAGATATATCAGCATCTAGCATGCAACCTATCAAAACGNAGAGTTTTATGACTAAAAAACCANGGGAAAGAAGACTTAAAGAT
+
%%)%)**$)*+$&'&'$(%&##))(&%*&$)%%%"$()'+"#%+)&(())"'*#+*%%"%!+*'*'+((%%#+"&+!)##"&&%
@r1664
GATATCCATCTACNATATCAGACCACTTCATTTCGCATAAATCACCACCTCGNTGCCCGGTAACAACAGCCAGTTCAATTGCAAGTCTGAGCCAACATGGTGAT
+
.!*;.9B,-:,5:!F6B==>)@%B'"HH;(337%C(:++F!)50EDD<%:!3&&8."(D,;/")<9+:B.8*7!=8A&&-6?+'>%=*;5A9B=C+"%6B340+
@r1665
ACCCGGCGTCTGGTCACGCAGACCGCCCGGANAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCG
+
'>:EC7-8,=@6.C2.9'GC528G=;*1+8*7GG%H:B"4B47-AG2*&>+.B,?+,6!277$*3&E*,>2B.?%"1"
@r1666
ACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCNTGCCC
+
$B7C(>$6?!8$*,4+G,GB'EC#)&H-'>"%8D$(/0D/;0&3!($C'4*2>A"#0:19@*D.F(,.1396>%1+2E")?>)H9E?B'E-EH57E%'82H"A0A747=H/6E+.25'>4'%#1"=/C6-#2-;F%37:1,&9:>,#,C-.'<3H=5F1D=*B=5-$!.+9A1)$2688#054@-
@r1667
CNGGAAGTGCGGTATCAGCATCGNAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAANGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCANCAGCACCAACCGCGCTCAGG
+
#!'*7=$)#.1'/H#350B#H'>9>;A.9F53&=075',?1#+?-9$C<#71ECC-FH/8'D9=5?;6*E5D<>0+F&0+C$A@C(A/96+#%H*4A8&(!>999@/:$EB#;=G<.FB%B1&E:<-D=G;E2475G2'A2@:!)63FC%%05+2;!/G<5+>./H2;-H)*=#71,)+)))&.H"F?0%8G7200C"2:4G!50:?&A<637*$9C>C3%:#D-G&7,/9D!9660,>-E+B(-7,%C@*,*<+/*EG(-A5"+2H;"%&)43)BB5CD>4@F?":#-
@r1668
NNGCGACGGGGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGNGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGNCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCNGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTA
+
(0#"C3,A?;*E<?2,<9=!+D<69&&7D3'7H&2!7=;+E*6*-F6>,4F13:*?835/$82'&!?!-&8/%C(#;.G0%/3=)9FCD6C99:#9A3>-<"5%?B!7FC>B34".D*9*&>F+$A7G$-HB9>F8C6'G!+2"1@"4$$:<D*6+/9'%341F7$@*4GD-."C@'D0=6'#7,@9D.AEF=)**8DF+4D4855*;"33#.6G:*)?7";>#8!+F/C);:@&213:<=#,A,A?.)*$:.%@6'$E.09.0?8$#!A#'"/GA7;9G5",;:(A#HB/AEE:#;,=B<!60%=+.3"<*(%)0+.>%431F&
@r1669
ATNGACGGNGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACNAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCNCCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCNGAATCGACCATTTCTGCCATCACCCGGGCAGATTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGNCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATNAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGNACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATATTAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCACGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGA
+
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
@r1670
TCANTTCNTNTCANCTANGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTNACTGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAAGAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCNTACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTGTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAANCATTTAATGCATTGATGCCATTAAATAGAGCACCAACGCCTGACTGCNCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATNATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATATCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGG
+
&&(&#*!$+*%$!(+%&+$"")(%'%"!&##&%($$%!#')'$)#"&"+%""%)#)%&)*'()+()&)$+("++"*%+"'#*!*%'(*#!!$%)+#%'('&$!"$("&)&(*#!#!()%%'%'$(+')!!#'$!#)%$'*'*+!#)()#*%!**'+&'*("'#))(*'''("!!&!"#((&$(+$))#(#*)#()&!'!''+&+"'!#$*&(+"("'!("(!#"+&("+!#!""*$%')(!(&+!(")'%"&%$**(&&*#$*!)%&!&&&")(++"%))%#&'&"#%&("%!)%*#!##***%)"#'*&$!'&&+'"#!*&!(&&"+('*#*(#%+&('+*()(++$"+$*$+#"$!%)!(('!*'$#&)+"!$)"!$!')+)(&%"#$'++$)"!#*)!#(*$!&)&&$&$+*#%'+)'+##'!('%#*)!(!+#+##$(&%*#($#"+#&)'*#)+)+)%'**&"#*(($"+&#"$(+)+*)"%&&*"+!%(&*%'"%+"#!%$$%#$''"($%"++*#(%*(%)%!%"!#&'+&*)&%+%%)!%))"+'+!*#&&%!&"(%*!!"(&&&"(&'!##!%++)&&)"!&'%(#%&&*$("%((&"#"%!'$*##!#**%&'#'*)($&)$!"#!(+$(%'&*'*'#(&)#'$)*)'#$"*((*"&(*!*&'&+(%+&%%!+"'"+%*()#%'#%**"+#%%)$"+$"%)+%'$"$)$#*)$$$"%"$*$&'%$"&$+#+&$%%!&($%$##'%+)*%)&'"$%)#$$*+#'(''&)!(+)"'***(!)'+&)%$*"*'''"(#'&($"*%#*$()''"*&'!%+#%"()*!*%"'!)"+%+#'("(""%$!*(&(!)!)$&'$*"(#&&$#$%"'+!)&)!($*#)&%)$(('#''*&($$)'('!$&$)+#'#&!!#"*$!++*"#%%&+)**$&%%'$+*(&)!"''))"++!$'(%%'!%")$%**!#$'"($&+&(%+#$'+'$$))$%(((&&"!##+*('+%((!
@r1671
ACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCANCTGACATACATTAATNAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATT
+
0>+8CE#:FD,:0,A#+DFC@$H%!:".@@%3D:C0-8@@#1G!$8<::0C=/'35(D'=+2*%16!(@B;0?",4"@@G2*"/G-3+CB!=!>BC1<6AD9&#B#&9$H"/+,8%$6F6:35&8-$1?@94%6->HDE&GD075H&%-52'-.
@r1672
NATATCTTNCGAATGCCNTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACNCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATANCACATCGAANAGGTTATCCTGCCGCTGACAGTACGCTTACTTCCGCGAANCGTCAGCGGAAGCACCACTATNTGGCGATCAAAAGGATGGTCATCGGNCACGGTGACAGTACGGTTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGNTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGG
+
"&)'%''"+!&*&++'$&$*&"&"&#("#!)(+")#'!&*$+'++)'##$%'('!"(+!"!*"+)*%!+)!%"+*#*'()''"'(**&#"%)*&#)&)!$$+%($"+$#"'")#%+*#(!#$!*$#+%)"(*%+!#+**#(#''*!*#%+*#"$+&#)'")$&((**&%&+"!#(*#)!!'**%)'#!%%%'!+*#!*+)'$+"!**(##*("+"%$!(*+"'#"$*+$'%"%#%%&+$$$'#('+!)'''+&(&("'%"")$"#$!#+'#(#&%!#$)"'"'+)''%)!&&'##)$'()+)$%)($!!*!)'%%$!*#"(&*#&&&!&+'+)#*&&(%*)#"'&'"!#('$)!$*+('!##%!%%*"!)(!%&$#'#$)%#'%'%&&#+"+)(+#($"!+*%!((*%#!($"+"'+!%+"$!$)**+$'*''%&$'+)**&'!)*##+)$)%+(%"#$&$#)(*&#&("%+))*'*#%'%
@r1673
CNTCCAATCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCANGTGGCTCAATCTCTTCAACGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCT
+
%(<5+?E#/+)<&D$)7-*?E"*11&A20-H9D+F:0F70='&.C1E(%D-A.0$)@*+E2;"G#32@0=9);$&>7#3%3E@D*3A6#@/.E9?3/;-<;C*%C>(C/23=B0':B=)(AD"HA$/2>E#',<9)B4,%4C/"$25?1?#'H>-<%$=60A:=:AE1*@6,*&HGE2#(0@1#43%8=955EFA3&%59..H1(,=>B
@r1674
TAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATTATCTCCGAGATAAAAACAAACCCGCTAGNACATATTACGATGACATGCTTGTTTCATCAGGTGAAAANTGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCNTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTAAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTNAAGTTTTCGCAGTAGATGAGGTACACNAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACCGAGCTCTTCATNATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGNGGCAGGGAAGCACTTGNGTGAAGTGATTACTTAAAGAAACTCTTTCGTAAAAGTTANAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTAATGTATCAGTGCCTAGCAAACTCGGAAGAT
+
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
@r1675
NTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCT
+
!4E9*>>2<D)+(/&(#(>(<''@CB93;A>'7C@@"7$01,8A?0<>H2)-4.-2,A*4G;H3/H03C>!,9C(/@?AE&G18+;0(8+97F<.HCE91D)<9,@5)8>A!.,#4H%:#?/*8>=+4E'=#A3$.-H:)BG4*A4B)>)*'CC0(#(HC-E(&%0<7C.)43<,$D7+>0=8#E9&5+>@:!A)%>7!H/?HF#B=(5;2C!,@,.F>85),=<5$=EC33&!<!@FC;1+A,;)7":3D:!2@-#F.)5#$&70),3%,-#4$"G*,'69,H@9/1+/;91&7""21+1?FH/&H
@r1676
GCATGTTCTGATACAGGTTGGTAACCNGCCAGTAGTGCGCGTTTGATTTCC
+
8A:<<@9(-A2F/$2;;C5H%;F%,(-CC7</!?8C?FCB+61$((/"/*?
@r1677
GCGCGCCCGCCGGGTAACTCACGGGGTATNNATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGNACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTNACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCATTCCATGCCGCTTCAACCTCGCGGGAAAAGGGACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCNAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTTTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTNCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCNGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTNCCTACAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCCCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTNGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGANAGAAACCAGCAATACATCAAACGCCGCGANCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACNAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACNAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTGCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCANATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGANGCCAGAGTCTGTAGTGTCAGATGATNACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGNTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAAGATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTG
+
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
@r1678
ATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACNGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCAGAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAA
+
G4&<643-+><)7;C6;B#@/-H7&3"?.=87*80>E$0%H@"61B4.'4%:,8E1&82C8G"%>E<*1<&(:69$4+/E*.52F6EB<+>?45=71<*,"=/(8%E.$&;-G<%(600H6"6D*@9;"/'C&4*G-?)"+G2,&-).8//)2B;H/=7HFB99,6B#$)66F>5F54=GE86*&2+7*=#!?!$3&F/(#$!#G?,?
@r1679
CTGATGAGCGACCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGTCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTT
+
C:A=%H0348#F68E)H5@(;.+D6#;%"DF:'*/:%/54=A7D(5*)")*G&.>=4F30!H6#9BGD+,$3G=074*=!<:!9<(%@4&(H3FFC!);&*2,**6*;/3AA2@"3CCCC<1D!%+C2D2BC:;2B,#)H,:<!&<$)6/5F()=C@.+;:@7,=+*8:7,!(A+1"H9&2!9@/4)@A4<DD?GG-5#@,A;&,BB=>-/370(,"=A!<G6-D0/**&(&3F)+B>(+(F2
@r1680
GAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTNTGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATNAAGCCGGCCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGANGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGNTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCTCGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGC
+
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
@r1681
GGTACAGAACTGCACNATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGNTGAACACGGTGGGCTCAGAGAATCCNGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTCCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCNTGACGGAGGATGATGCCCGGCCGGAGGTGNTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACANGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGNAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCNGCAGAAAATNCTGCCAGGGCGGCAAAAACGTACGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGATTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTCTCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAANAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCA
+
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
@r1682
GCATCTGTTTCTGAATTTCATAACGGGCACCCTTGCGGGCCATGTCACACACCCCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATAAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAANAATCCCCGCTNGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGANTTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGCTTATCGCCATACTGTTCCNTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGNTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGNTGGCGTTTGTACTCGAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGNGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGNAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATT
+
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
@r1683
ACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGNCACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTAAATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGGAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAAC
+
B@D=?5%4256)D1,41"!;*,(7:11DF)3F@GB#C(#!+,0'+)0>E:'(FC@=!#&725!@!7+E%D2'!,+#3$H(;0E<DD4E.).F15G$A>5G+34);82$G+?E,5H..*+!91)$F58B0&3;606%73;.!%(!*4"@.$6($4FF+'A>5C(:6!>$>&D72<-C,C8?F:&05'/%=);>*$6?6.?3F:%DB=B95$:%CD!&1?(#2&G;E*1#A.)'3%E!"!A82!3$1:.3'AF&17)5FFEC*9$6;,!4@A1F;4)/&B3'0?-?-18>#3E)G3<G$*9>?-=1A<F#/DH*D>575%)+,FC3.;=38/;AE$+%;5F=?0E:D'==!.890'DA@/E.BA!DGG?7H>D&?!F&&:A':E)6%"!4*>>CCC1C027=/!*&D2::F7%#C-2D9<A3&D7A#H.,1?!$4".1GAC/)$'")#0H
@r1684
AGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGNCGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGNAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGNGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGCAATACAACCGACAGATGTATGTA
+
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
@r1685
CAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATNACC
+
4;@FB1>6%CG8'53BC;5*"*A)5:9?$@?>BDE%-;G=$)#??E-8+*H-1?9D=4'G)&7=-53:A)5;D->C6-@:==@%2;A7'67."-.FF4:HF(2>(1=H<>0:=<5.46!B78=48>#$AB3;'24<!<H&
@r1686
GCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGGACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCACATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAGCGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGN
+
B6702-D0'359*>>(!335$#FE6@$6D#97;19C:6.,*8D=7'2'9;G4@=G/!H=3;4#?+:+'/<-(FE=,<+B8@*7%H+.5F5*,5#D(;:!8+!;9<A76F*6?3=:2:C?<&!#,;E"6)C9?;,'61-20.?)E-2:4H*8$=4GB1>/#::B".,D*-&FB!E86G1';@%0?B=?A-:<F63".29%-5<.>:@!3>5%C4FH"$1D(2%=2:"F7<CDG10"&)/C8:F-*+,G2%.F<;3%&69,FA$%(?HGB5%04D",3!!*?(5!#''5.($?#FG/26,2?)<<?83/70?,C:"&$@B/'E39"6?#":A>0!?$&(6&1;/527)/#:GA!)%<!')6'%E2$96.0<C"=9:!<,*"1:1@BE+((@/270;*-)78C!3.;'E?DG$>8)>64/0=BD#E@'25!%,$&E!5$0(!@'&.H!GA$@CH"*7-)F';=%?1
@r1687
CGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTNGGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACNGGCTCCCCCTGTCGGT
+
E/6-F?&@A;(+7/238(#<)/"C9<H>-.43'?=-,$3<61&/%=9(#H:5?*@%95)2?,,D%5962'%%=G+.5>#$29$;>47G:E8:?:4!"56H?C(7&/3(#=)170AB3$$/%3(2:9&"8C%0"?65?F5D@*%*2-&+4>C3-4E:*%5%75#9AB$$':<8G:0-568C)$!AFE!5*
@r1688
AACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGGAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGNTGCTTTCCCGTTGGTGGGATGCCTACCGC
+
9E#=.=7"CE3;D6G249=F0:-B(%-A;H/>,0/F=/:0'.,7'(/8A6H@05C6=C0D:32)H,G,0&*#3(+A8C$<=8?3,A7F:!/.#4CF'?*>?!2%D$13952=31$<!%H.18=9+?$?AAGG;EF3*=07#&=2'23B))+1(D
@r1689
TTTATCATAAAAAATTTGAATGTGATANCCGTCCTTTAAAAAAGTGGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGAAATTTTTAGGCTTATCTACC
+
878&)A7F7%%6-54(082E7)&B"<.@F3*.:8/&$<<EH%/8&'H0(:&45H.-G10!#GG-A5$!2*175/.+5#@;%G2G7.;!-1G51E*@=G,G1G1H(#954.9,?5%
@r1690
GTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTNTCAGTTAGCTTTGGTGGTGAGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCNCATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTCTGAATGCTGCCCTTCTTCAGGGC
+
2'G;>(?(*"E-?4&<A?*'<'#EG*D55'1C4?;1H31C5A1-/$/H,9(D75-7B5(;!(;>+A8+5)*7B"C99;@;+)*":2.C*?;$6<B<>0'.2(E55.'.FH/E+-2D(<3CF<C#?48;660!<-=FD94/H*2(EE"G$,.8(7%FG5C"#75""9)%%>=<D?,8H2H+$/--H7A2E<((+A9577<8G
@r1691
ACNCCATCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTCATGTGCTCAGTATCACCGCCAG
+
"%*#"'"+&*!+))+$*'%$'%%#$&*)'%&+'%(!'+%))#"+**"#+"!'&$+&%!#)#*!'*)+%!(!+$#)+*#(!(+*("
@r1692
TCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGNATCCGCNCAATATTTTGTTTAAACGCCGTGGTCAGC
+
C;/C+'6.'"&1"GG)/F6!:&G@//41>>D9*3%FD47&"1C,C2'=H3=C/F*</3,B:-2B'(;=.$8HA#$(9>3/A>=0=B?F105.:):'=!$G!".>=-%"<>7A.B$EH+H*#/(0"(#<45/.8"G%0*"'6G.%HFH:6A3+%;7BB3!A;6::0>8()93;C"/2:B>=8B1B(!"5>*<&A>-7?&%%*%1",=BHB*:77'9)3.F88)9&G65!2/".>;3DH)C@??)94?<9BH.*&*&6/:7"%?7%0C$#6-E5FCB*E@?332H@3-C12!6&=2G,H927D8<.:.=E?*F/7#&'.A+&57!1'FH=AD(%;,/:H?*GE+85=?.
@r1693
GCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCA
+
,B,(9H>$-9E%76<9D?5"?#"H).&69/H(*'B::-%8EE01D*###A,8(#C,>&.51,;41E%1F:')'960!>7<!C*.-@""''9
@r1694
GNNCGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGCGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCNGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGANTGCTATCCCTCAAAACAGGGGGACACAAAAGANACTATTACAAAAAAAAAAAGAAAANATTATTCGTCAGAGCATTCTGGCGAATCCNCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGAAGCTGCAATTCNGAGCGGCAGGANGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTG
+
#$*!+&+%!"&*!$+$$%(!'(#*!(!'+(+#!(*+*#)$'!+()*%&('*#%*$"(*(&'+(#*!&+)(#"+&&#&#$")&%*))%&+#'"($)!#!+*++'&)+%+(%"($%%*%+&(*$('%"!*%+#(*(&#'#)+"'!!*!)#+"#$""&++*$+#)*)'!%+((+%$%&'("*((&'*($!*$"%()(+&$$"''%%*!((%)&'(%"%&#"*(!*$('+$&+&($*()((#!#&#&+'+)((*%%+))($&$"%%%#&#"'**&"#%'$#+)!*)&"*"*%'(#$($#+"&%(#%+$!*+%)!&+(()#$)*$'"%'&++$('(('(*%&+%*#%)$'&+(#%+$*'''!'+&!#&)"'"#&&&#!%%$'*"$%($')!)*"%"()!%**+%%++'*#'"**'!%"+*%$)')$""+%"!$'+(#)!$&$($&)'+"+!%!$+()))$("%!$'!*)&(&'%#+)!($)+$(#"+)++*$%+%!#'#($()#+*&
@r1695
CGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAANCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTNCGCGATAACGTCCAGCGACATTCTTCCTCGGTACATAATGTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGAGTTTTTAATGCAGTATATGNAGTTACCGAGATGTTCCGGTATTTNCAAATCGANTGGTTGTTGCTTCCACCNTGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCGTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCNCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTNAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGNGATGTCATTGGATGTTAACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGNTGACGTCCTGCCACCGNAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTNACCACTTAACGCCACNCTCTGTACCGCATGC
+
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
@r1696
CATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATG
+
/H&+46:*(7<69F$?@@-&)"7?G;@DG'2C6'6'C9882:#=DB#23<=7'@4$F?#%?$(G#/0:AC(B#(FGH"00F8:<
@r1697
AGGCCTGTTATTAGCTCAGTAATGTAGATGNTCATCTTTTAACTCCATATACCG
+
:9D5;C6+5?>.3))"=G;H>E;%E!%+DH&@+D.GD)).0>3E4>7.3+&'&#
@r1698
TNACTCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGANTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACAATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGNCCCGTTATCCACGATGGCCTCTTTTTCCGTCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACNCCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTNTTCACCGCCAGCACACGACCACCGGTGC
+
$$"'!++"#(!(*&#+#*($$*""(#)*!)%)&$)')#"'$'$%"(")"%+"##%%"'%(#("+*$"('$&("")%('$$#)&##+$#$(%$)(+($+%+'!+$&)%*))#)+&$%%+%+#*'"*)%($&&!*$)*!&!*()##&*$)(*&&'(%%+%#$&&#%!+*)')&%%"#"*"$#'&#&#*)#'#!##)&##(*(*"+(*$&++$#(**")!))"$&*!!"$+*!"%%'")($(!&*##(#!$'+&!&+!#!&'%+)!!'##$**#&#(+'+)$+&((()%&)%**#+%"!"#$#%'""%!"))#'#')"*"+)$*+')'+'$*"'($!&&+$""!"#)'&#+*'&$(("'(&"+%)'%%$('%+!%&)*#"&#!*)'++!"%!**)+%%!&%'!%#!%(*!+'+#*&$$'(+*(%*%#*"+##)%!)%*&%!%$#"#%"#!%#'(&(#&)(**
@r1699
TTACGCAGAAGGGCAAGCAGNACTTTAAACTGTCGCTTNGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTNCCTCTGCCNAAGTTGAGTATTTNTGCTGTATTTGNCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTTAAG
+
*51*A;>$,%)))@"#$+*?$B3<9$24.3:*%"6+65D:78(F@/1G8D!>!51G'3:07B9,D0D38A.'5C*3-"9H=/2E+"$)1@,>A/78B;?EC1!7);6.<+9E!5E51D(5#?CA=HF3/-&#/0@H48H8DBC&2"F3D7C'7'B34*/0,6%A(9!"=%7$"D"-2*)A?:AFEB/().3C&;A.E>0>F+5&3&'D,B97"5))EBBF3&B67-1((-%7.@5!;@29#!0=/3&2&#!"?634"CD!119A@!:EE02!D>//*/@.)%E:77&68.6>C&3-"'77E9>8;+)-=B#/A;--=/-"AB,(EG?/>4,
@r1700
ACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGNGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACACAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACNCGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCNGATTATTNGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAATTTGAAATCGACCATGACGTAATGACAGAGGA
+
;88$(,+0?3!C4*D2+,)%E<0"8F*7%2E;.(:.9-&?$(2),"61&;F'5ACB,*'EG"+5@$)?+H-4)"G@A)$5.=5?"A(-#80/$D*2!'4F9,A@"<D.;G$,-7&?&6;/=D.2B-53+2*%3.C?/<5D>(,3)#2-75:7=<5>9)2*;H-:E)1,A7&)6B</,671,!-1)&$@=>+%"D(?*(A#79>4E'<-BB9@E;$.)$.;F*;-63AG4A/486":(%9(!'CBG1H2.)8/:%!B0>?*%G.37"C)C,*"'H'A--:>:/HE@$?!/(82F66+,'C;6'><*G&?<522'@=./35(A58+3B8*E7C%4E57<;B'')&56@"%<92BDC<'7H8/73->2/@1&2>);;8*($=?-<,H4(80,G8$=A07F?<)B'83=")-:;5B7*;C?@02%11;'=)D"1)!F!25H@+?4,BGB0BE?#*F0-,@82AD6/D%)&/H%1E/4:3+
@r1701
GGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTGGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCCGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGANTCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCNATNCCCAGATAGCGNCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGAATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCGGCATCCACACTTTCACT
+
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
@r1702
NGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGNCGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCT
+
(A*"8G.'1(4&;#$+,(3*D+(>?-C.+?,;%4=8$*"9%035$(19+@1(H)*2.@('.:3!E6=$$<A5;9/#(E#"3G-EDC#H99"'.+=@+5!AD!$,0#?H(E/!=<,&G:!E/#;'&7+=C"A1B*<DB6C=
@r1703
GCGGNGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTACCCAGTACAGAACAGGCAGAACATTGCCCTGGGCAGCCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGNCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATNCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCNGCAATGGCGGCAGCCCCCAGGACAATTTGGAATACGCCACCTGACTTGGCCCCGGCGACTNTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAACTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTC
+
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
@r1704
TTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCG
+
5#%@$#3!%%&>0(H)!4H""C-:A#&D!9-B=.62:&FH7"*
@r1705
TGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGNCCAGATTTGACG
+
*C?+AA4.F4!56"=3:'@:;F;)#BE8,@"22-.%9CH+%5?"G>EF%>?5!FCB=&1B%E:F)9-BG36;@7A@,1D*5&/#B:&4/132B>/)9:(4<A:-9)*C'<@G*<9/+:6)D>2A2@$1F,!!/G>GC>D"*82(,",D0<$'+D!!>0;4.8E57@332?A)*3$7?$/E,0-%!%0C61?"?1)$,4%@+F+8F1D2#!=D>>*BHH:2&E99#$#C3/@H&3:-7&<'2)(-D&'&&6D@/&236>E
@r1706
TGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGNCTGGTAAACATGGNGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGAC
+
''1>H/"4(1BG$:";B+:$<0F8E+C72+5>9A$5)./H$1.;3!(GH/$+*87&/>6-#%.6;>,;@A?8&=27-F3<G/.B4*B=F:;+=$(&,*.?54.;'A%8.(54E/%8&F;98>;H;*7(#0##=>'2;'@A((;&B?G.40G%(6>=(%8F1>*0)>:"*E61DH,$H40H=.GB69$F-D.=G):E=7*(&-)@+&)!("!=G1-A0A&F)%=!+01.!7GB%/!A(%/3A5-7,6'$,?0+"?<*%>)<73"?.
@r1707
AGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAACCTCTTCCAGGTCACCAGTGCAGTGCTTCATAACATGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCNTCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTGGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCGTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTCTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGNGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACANCCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCANAACAATGAGTGGNAGANATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGAGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACNCTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTACATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAACGACGCAGGGGACCTGCAGGATTTTATGTCTGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGAACGGCATGACATCGCTGCGCGAATATGCCGGTTGTCACGGCGGTGGCAG
+
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
@r1708
ATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTACACCCAGATATTCCGGCTGGCTTTGTTGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCT
+
0*468"7G43C6B@=;.C@HHA@-DA*<=""G9G3-728.=C.&BB@%(2700)20E7>BA>1B8$*-<*F8"8H?BBD#G<'D2!1B32./.'@'3@&3/257=?E"3%/%5@H#6+18,+FHEC
@r1709
CTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCNTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTNANCCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATG
+
?D$$;F9-;26H-H2<B$"??1+4)B&B):9E;E97,E1(7;:@+"4@#F?0H9<%2</8$".+2.79G/+=E7(H&$-$A=22#/?/5-@1,G"6343H-A7F/56"E-1$"/0':C?G(0D03;>+4.5:#(A9A$0H4)B3F&/89#!@'6"A:/'!!),%54.*75%:,
@r1710
CNNTCNTCNTCATCGNGNTTNNGGAATTTNCACNCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGANTGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAANTATTTGTCTATTCATAAAATCGATGGAAAAACTTTTCNCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTAAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCNACNCCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGNGCGTTCAGATNGAGCCACTGATGAGGGGAACCACCAAAGACGATGNTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATCTATTAAAGGTCTTAGGGGCAACAGANATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGNAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCGGCGCCTCTGAANAAGGNCACCAATGNTGAGATACCTGAAGAGATGGCATATTGCTACGCAAGANTGAAAAGTGATATACTGGAANGTTTTAAAAGGCAGGTGGGCAAAGTTAAGNATGAATTATCAGCAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTAACGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGNTGGTCTTGGGGCGACGTTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGNCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGT
+
'$""'&%'*%*('$&$!$)!&$+'+**%&'$$!%!*!$+'*'*(+***!)#'%#!)%*"))##(&"'#&%)(""%!)&"#)(#+($"!#'%!*%*!+$('#!$&))*!'#("*)%$""+))"("''#&+#+'%)(#(+*($+&%'#*(!+)(*##+$("#"($**('"(+!%!#&)!$!%)!**%$&*('+!!*(%(&!!$!%"!"+%#&$"%&'#+"##*%)+*!($*!$%)#+'&!%$+&#"+(*&!(!$&$%"$*&((&$#(!%%$#'$%#&$')"&(#+$%"#)+'$'')#)%++)*(#(+%)$'#$'+%*%$*(%#+"$%")((&++&&&!&'(#'$%%+$))##(')%!'+(!()*&!!'%%#$&$#&*(%"+'()'&%+%)&&"))'(+#$#*+)*)'++&'"'()&($")("*++&"$(%#%!'*("#(')+&)!$&)"#!"'*"*%(!"""&!"""(""**)&#""&#**+(#+&!$)**)$!&#$#"&'*)''#''("#&**&!+"%&!(&+*!$*(%+"'''(#)$)+$%%&*$'**(&!!$&"%$+%'$#&'*+'"+++()*)$('))+!*(!*"&$*+#'!(!)(')(&!(**%%+**')'&('+*!+&+("'(!+&+&)("&'%)+#+!*#"('!$)('%)$%++$!(*%"+&+%)$&)&*$*'+)&(!(($'*'(!"$"%&!"!%&*+&%%"%'!'%!!#('!'&#!)))(!*&#*&'(+!%#+&!++))("+!*%""$#&(+"%"#)(#!)!'"$&&#*'(""$*+!$++*!#"&$%%)!)*('$*)#%&$"++%#!%#$*"&*"(!(%"*"'&))#($(*&%#(+(+"%&!++#+*%*(&++!!*%+)%*!#!&*!&%"+")#(!%!((%**%&*'+$$#*+&&(##)$($)#*!%"++"+!%$!"$+)*&+$%$*""('&)#&)"#))&*+&(#))%$""%*'')##&($*"$$+"*(!%$()+#*$%"&)!#+*#")$"%!*"*%*('%+((')+&%&$!#(&&#'%$$!!(&$'!&"(#"%#'#+)&'*""*)+")%*'$#%()(+*%""&##&'%)!(%&&#*$&(&&'")#%##"&)%'('+)#(*"(+&'!!)+#*'*!''(+(&!$*+"#(%'!%"&"$##'*#+!'$&"!$$%+'$"*&!%++&'("
@r1711
TANCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGANTATTGCCNGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTTGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTTCGCCGTAAGGCCGCAGATGAGCTTGTNCATATGNCTGCGAGAATTNACCGTGGTGAGGCGATCCCTGAACCANTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCNAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACNTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCGATGAANCGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATNACTGAGCTAATAACAGGCCTGCTGGT
+
$*%+"$&%!$&)('**!%$'&$!+("#*!%&*#*#*$$&)$(#*((&$#(&+'*$")$!+$#%%"+$!#)*"$*$'"(&"!%$)'!%$$$#*+&!+($)$#++$'!($$!*&%#)'()!%"!!)%($(#%*$%'')#$"(&+"**)#%!%!$(!)++!)!+'$*&+"(%(!&!'"#*#%&'''+&!'"%''+!(")&#""*'!*"&)(!&*!+&#++(#+(*"%*$")%$+&))#'#+$(%*")*("*#(*%$+$+%'"%*''&('")+&"+$!*#&+!)#$%(%()%"'&(("+"%!"$&)("%&%#+%##%#&!%*(#("!)")*'+!*((#)$%$*#)!%)*)+%*&%)((&"(')!#!%!(&+'%)!'%%"&++)"&%'!)+#$*%%($'$)+(!'&((#(+)+&+&%*")(*'!&*%'$(*)!)+(#$*+&'""'##%'+)+$$$$(&#'%'*!+)$((*($'$'++!+%##*+&)%#"&%"*(%#*('&!(!#&"!(#)"'*"*$(!%&)!%$&**"(#"(#*(!!+'+('*%+&+*+'&"#%!!(&#(&'"$())$'%+(!&(&(*&*%"(#'"+!(!*"+%$(%%+#$""$'&"'#$!))#+&'$)+#*$("+"$*'&'%))&*+!$&'"")*#)*!$!"""#%&(++%(%$(%)+)++'"&*&)$"&"%%#!*"'')"&"&$)'#)$)$'$#*$$($)")%)*(%#*%$!+#(&)$!*(+#)"&+))#""()#(*#"(*%"&!*("
@r1712
ACANGTGAACTTCCNGCNCATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGNCTTAGCCACCGGANATCCCACAGGTGAGCCGTGTAGTTGAAGGTTATTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCNGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTACGTCGGTGATACTTCGTCGCTGTCTCGCCACANGTCCTCCTTTTCCTGNGGTAGTGGTAACACCCCTGTTGGTGTTNTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGAGTCAGAACAAGAGCCGGTATCGAATCTTTTAGCACGTACCATGTCCTGATACAGGGCTTGATGATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATNACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGACCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATNCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGA
+
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
@r1713
CNGTTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGCGCATCTTCATCTGCTNCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTAAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCNATGTCNATTNCTGCGCCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTATTCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTNGGGCTGACCATCCGGAACT
+
$!*#+!"#!!&+%*'+$'+*#)$)%*&!+)+(#'#!(#+("#"%(+"(%#%!!+%&%((&#*%&($*"%"*)&*+$&('"$%)+('&$$%((*!)$#)!&#&%*++%*+')#"&"&+")%*&"%'#&!+*$#!%%"**(!#"&*+*&$*"#'#""("*&!$&($+$&*#$"'&+#!#$)$+%*%+$')'))%#)"!'&"$*)+')"'!$*+&(#&%%!*#"%*))$$*')+)"($!%'##(*())*"*"$%)!("!$$&'+**$*""*##+&"*'+$"($!"$+&&!!#)')%!(#'!!!#'+#$*!&#%)++*$*!#)!#++"!'#+)((#"'"$%%!''(!
@r1714
GCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCANAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTANCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAANAACAGGGTACTCATACTCACTTCTAACTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCNATTGAAGGGCTAAATTCTTNAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACNAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCT
+
266H@7)3G>:9,&)C#5.7<A?./?"F;&)**H)93(D+H89>"5#6%776*:.1>*%2"2$?!1@DF2*<6*6$1C.0=);;&10#"5G&8;?G%-GD+5':",>)-3D,-/<8/6!+:CD*)3;2!;14@#00.$H*H-A%A%DE1A+/71"5G,B-;76"6C:C',"0)3'G9B@%-7F9%0'3&#,.CD3;!*<?-9#'1*(.(<"4.74D+<1D<#>5:@,$!>;F"<@+9<2$0"+C(2."><0#;*8#0)3(F3HA3D:&*!.H8,E)4(*2-4$">?>$%$0C&=B#&G3,B/5&+;%@GG'D**G?G#(>2B.;8*(*2)3+8+;*-/*4H!+&(D)/1#88=*/BAC%?((2*?;'-,5B=>!,32'!H,E@GCB8&F<HA+=45B<+5CA&(9.!A*EC#=F"/,;="'7C3/DD-E;G0/@;83E(2<8F!$!/=9-:5,.;F5%2B1)3,B:DEHB:7:&?-&,9A5:+5<,8!&"!
@r1715
GTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTNGTGTTCTTTCACACCGTAGAAACCATCGTTTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTNCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCCTCACGACATGGGATCCCTTGATGACCTCATTAAAAACAAGCTGCAATCCCTCCTCNTCTTTGCAGGCAAGTGCGATTTTTTGCGTTGATTTTTTAATGCAGAACATGCAGTNACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATANCTGATTCCAGGCTTNGGCTTTAGCCACTTCGGTCCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGNGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCCTATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATAT
+
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
@r1716
AATGCTNCNNCNNNACNGGNNCCNGANAGNTTANNTTANNGNNNTNNNATNNTCGNCNNNNNAACTNNCGATNTAGCNANANNNANACACGNANTTTNNNTTCTNGNNGNTNACNTTNNNGCANNCNNTTNGNNGANACGNGGTNGNACTCNGNNTNTNTCNACTTCNGTNGCNCGAANNNNNAATNCTANNTANNTNCGANGTNAANAATANCGNGCTGCNNANCNNGCTNCNGTTCNNTATCCA
+
$$###""!!"""!"!#$$#"##$!#"!#!"""$""$$#!!"!"!!"""$!"$###!!!"####!"!!!!"$"#$""#!#$#$$$!$$#$!##""$$"!#""##$"!!$#"$"$"!#!!""#"#"!#$"$$"##!##"!$!$$##!##$#!$##"#$#$$!##"#"!$"#$!$!"$$!#!!##!$#$"#"$$!!$!"!!"$#!#$!$#!"$"$!$!"#"$!##"!"#!#$!""!!$#"$!!#!"!!$
@r1717
GGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTCGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCT
+
#*)'&#%&+&!%')"$"+##'(%#&*+(*'!$'"&*!"((%%*"""%"$&&%&('&&#)+'+'$+)$&*)*+&)('(!
@r1718
CACACCACGGTATTTCCCCGATACNTTGTGTGCAAATTGCGTCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCGGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTNGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCNGTACCTGAATCA
+
E."6>)<A'>91>&;0#5&5$9-*>-9+*4!/'$;96$D$@<8(:&0@*3BE-H-<+@/8CB?,#(C%"?:%E/D@732<9E>;;H?B/;592:'H4:#7.0:"E31@+3?4.<*@DBA&$/B&99/8/*6-.>90ECE&!,%,32*1A&.,?E'F(<F74&D=->C"55?GDAC48%#E%6HB=E7!F%B6?)35482(41$+E!GC&6!:31:C/=+,22@=*"2H-BB$C/+:%@&0>A6304,CH<&)+#()*ECH3G.H?8D)3(*4ED?90
@r1719
ATGAATGATAATNATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCA
+
:)(:(5:/B?C9'))3.G5HFH!.8"3)5"$$2F$B'3&@G#AH*&?=8F7&#983B(/3E;90H=AFB*?+(18'?.+<.73%4?F3!-&;)D@#/+21+AC/)*9%34=$
@r1720
CGTGGTGCTGTTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAACAAATNGTTAACGGCATCAGATGCCGGGTNACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCNCGCCTGTGCACTCTGTAGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGNTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGGGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGNCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGNTCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGNATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACNCC
+
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
@r1721
TCGCTAGNAGATTGCACGANTAGNANGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCNAGCCTGGCGAACGCGGCATAACATGCAG
+
(%$$*$%*#%#!"#())&%&*"'*)$'+(%(*#%%*(!'$$&(!!$%%($'+*"*#+)$&$+"%$$!'()#&'$))+("$(%#'&'((!#(+$"%"%#*!&+)*)+'(!!(%*$"%))'#"&%%(+!##'&)&%%&*#'%*)$#*#'"##(''#&'!'!
@r1722
AATTTTCTATCTTTCATCATATTCTAGATGCCTCTGAAANAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATA
+
B1&$:;EE(,5*!/(3;<2C2+1E9A02A0E:'BD7#0;8-$2A9=""AB2:?"B0F'%F>@.%=D!#$8A/<2$0"A$/C%(+%3
@r1723
TTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCNGAATTGCTATGTTTAGTNNGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAANTTATATAGTTGGAA
+
;0-=D1FG.7)@*-HB>)>=0<44%?25,'56A!'=7DDF7"7%7/&6#%.)9/29B=:5%.@2,GC1B=9:C0'+A;""37/.&5)2>F6.3,F/24C9G6?#;@0!@#&CEH(B%G2,?29"4&/5!<)+'>?3@"=D7:HAG.B&"8=/*%6B+B-9@:>H(;347D,==CA?A9@@2$0=&H;HC<&B85>9,
@r1724
NTCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGGATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTNCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGACCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATNTACGTGCATCCAGTGCATCACGCGTGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGC
+
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
@r1725
GATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTANGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGNTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTNCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCGGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCNTCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGATGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAA
+
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
@r1726
TCGTACACAATGNTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCNCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCC
+
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
@r1727
TGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTNATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGCATC
+
9!==8("#2H,:53-G).,%+;$.!<4<DF-$(>G:!+!-)93H&0E)"3?&0G@1>B+-$<%=9/*4@&/(%B?E4&?*)B&A*/G0>B$9"-E3EB+?GA:7>#258'">@!$''9EB+9@7:+:)/&<)#<(;D0$392?:(E>A.B/$FE!?""A%>BA",H<+*H7@&32&E2023!';0FEG:("(1(!*23;'5'*E?9$)3#9*)#7E1"<F<&8F/-FA0FH7*>1E&,G(2HBEBA/*&F5E8!<G$-0-9C4?D+,F-8#=8#.G:7>5?H(49HH4<*=$%E6EB4&B4=!H6#@&7/"G+!-<9D4&2C0#.0:C>7AG!:E&#&%0:&H7F"#!B+B0<9=#==#(/9:%G?7A%,HH53&27?2*B:$,4(=?FG2/$%8CDF4.6'8&DH9&4B--9-A%)).%$&5F#/@?G'4<0E":#="A6!B&<,7EF?A0,??$6!5%9?#%#'")0D@&8B:-4=?&%?'D.G!H*:'5
@r1728
ACCGACGACAGCCGGAACNGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGGCGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTCATGGAGCAGATGAAGATGCTCGACACGCTGGAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAG
+
EG2,**E'6?$*4+3>FGA+HD%#'79'-$46+5+7&.$6+%!-)'&/(4@,>1D8&2C?!2;@162$%%H-46%1/1'B2$5+',")7/2@3'1%,!+90.$#,A>57:$90H<3<F6/D80E?1'3B3>7.E&C+27/.F;%G9397A-=>8=68(E?;B%<C:H4$&C=G5.+1<A:E5"8)#:;92+1@.-26'*47,D=.2)70>7!)$@*(*0-D>>,1)*H(0)2.5&C-G<A=/H0!$(=2;G?%/:$7,*%&@1!2+A#C)=3H)"HDC9=8F7G!1H)E;!8F-0'!5,(A!4
@r1729
TACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTTACA
+
EA!,,A=1>?(D=*@:=*9?5(##(;#*E+>;*5$5;>6,/=AC22,.G2*:'7+6/-65.=3*4$3&)*=6-AC592A>H1610'A5<1F%E?=-D-2/E,:=%-*?08D1=HCG#8"A$*",#-#$>)&'44/?$>$$G#F-"(F?0.7GB(DG.'D<?9!0@2)
@r1730
TTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGGCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCNGGTAGTGACG
+
/=<8<HGHA3AAG9$%0DD10%"&@(G&+&;,/H@::F"AH)E3(.E)$DC#:<ACB<+2<$8B+C*:51H'$$@!5D%H(%)2E7;D%6D@;4;'7G")/E'=B-)&@4*5;$&%0*5(FD+D)F.5%F?:FD"$F";+A?6FA48,+F?*>E*3>&3%BH/AC;&,E,5B73+<6*@"D1*0*);";*@/:4A4"FC6F90(D$:+C$F-E-A8%!,C9(C":;D225.84*6#=@26)*)C=/?&81"90A*&5/2$/6+,B&**9E/;G:=H7E"8-23,:;#:6F)?A'?@=@/0EH<0B+E*25%E1.=H+6'G3"$65/("5/D*/,!*5"!B-<:D:08A:E+/DB8BD8#C>
@r1731
CCCCCACCATCGGCAGGGTGATCGCACCAGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGNAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTCTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCCCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGNATCACTTTCCGT
+
:A:.<*$;F*;B8H-2H%B$29)33"?6'.4)-C-;>%;B10<8$$%16>>2@DE"*7#'-=3D(68@A)>%+#1+G,'F"(::(CF9F18D:'C-@-()57G),$38*:(#)3F-"@BH94#B-;1BH!E*?:<%'**7':G9A@18%>8"0%8+-%DD;:$,F+A,=81@(#7'7'7+>46H(>2BE93F;$*+1;9'4DD9:G$7$3,1EBA6C+)'".1=-09%.)#A+?7-17582"@05D+$8)0."3H:4%A>3*2'B#/D0)260!8-5
@r1732
AATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTC
+
81#G+,<HH,!8'6@E:2.67C9@/H2F/=?G+%-H1.80.G03'*"G&E##B6=;,1(*4#C"+.=4/+&<3#5'"0'FH>'E"#E)CE2,:4&':.</7G?G<,'+*,#
@r1733
GGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTTCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAACGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCNGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGNCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACNTGTCA
+
;;*?H&G1B+-?()C*,/ED)./4;--BH8!D&594>./ED=HC3G,$%300117@,>-.%95F@&H<G.*H977@0>(=!!D8#=8CH73=(!*%:)%E5#E5>*&G<>8!!@3;.+EH+#'9:-A%1G<%;GH"D5H(/#9/&*=D@9C#2%(!8<B8>%%+B8',1:?B"07H1H0CC4;>;<0@2>18>D;$/3'!%'?B*!F60.C'6'=-!*+G/(@D+);@>CG"21"9=D$)!)<-G=2F0#,6(1(79=20*GA=5<9;7&B&<+202$,31<7F/E)<GE)AC>F1AC5%<;4%650D+&4<+E@B3%D$"*97;.C11"CDBF-G0E1)B.;&.H.A4:'-=7+(1'("!4BG!&@D33!/A05.E74+EH><@#H-<1/H>7?(71<8D8'14@)@?:")4AA5=@%7+2BE,HC%3.!2):<F!)?H:-E1:8H01A'FC2E0#$*42@3,.B)4(
@r1734
CGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAAT
+
C08=G0D&6HB&-1&DG(.3%7<058G)B;6&(E8&>##?;'8G9!,=%%8E#?*H;=":+<(@%337A@.+2F2.FB@:/D+!/H>61>2"&)(<5CA+0@$H/9CF6=8EF2?F4%(9CF*FC843A?'3
@r1735
GCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCANGCTGATTTACAGCGGNAGCCATAAGGTGGATGGCAACCC
+
1B4BAD++7F,!H80,4%1D#)@@(+@):,/28%!H#4)!(7'171%/:>C#6=?&63@5/H.>F>&F@C7F%;$8$B;11*?8;(
@r1736
NAATGGCGCACNNCGNTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGACAACAGGTCATGTTTTTCTGGCATCTACATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTA
+
$*%)"'&&#)$$!%$+'%&*(%"!"!&(#*!)%%)"+$+$&)#('&#&')!#**'+*$&&#%+$(+&$&()*$*$#$*#)%&+*(#"'"!""++))$&"&'*)'"'#&%((&*$$)*&&'$$*#!$(*"%!"%*'*("%%$$*)#%+#$'("'&!(+!$$*%!"&'(+!"(+$"(&!'!)%!+"%($(#'++**
@r1737
GGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGANTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCACAGATATTGCTGCAACGGTNGATTGCCTGACGGATATCACCACGATCANTCATAGGTAAAGCGCCACGCTCCTTAAT
+
F8%)F8/96!*<%-8+H%0,(>/!#(+59-4B(;@=(45'<:@#;'<#>6B5'>*56')$$2C!C'5$++:5'A/'/,FF&B;(E:5E:?E8>+1!(/C<3'.B/<"'A!#!2+4;4/G!*E=5918+BFF+=-9!C3,*32C.%9$*BF,<7GB&&$2#HG<BBA.$6!%0@/@D'4(C"814<$7,.>0F+B+@96:"2@;F:<?E=/C+#%9@#-,&C<:D@%;8.8";#;D)HE08B?+B6CE2:3&7(($@-G89&3!667>%>!?F>8GH*B(3-5D.2
@r1738
AAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCTAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCGGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCANGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGG
+
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
@r1739
TGNTNTGCANCAACTTAACGTAAAAACAACTTCAGACAATANAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCNGCAACATNCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGANCAAAAAGGGTNCGGGAATTTCTCAGCTTGGGTCATTGAAGCCTG
+
(*!'(&**'%++"!"*"!!'+#+#!"$%('&+")"+'('+&%)!&'!)&$!!)++!&'*""**!%+'!%)"&%'"*(#'#()%%#")*$+%)%&!&)(#"'&)#")'"*$(%$!*"##(*##''%"%'*%%**"$$%()'#!+&(("%"&&&+)$"$)+"#)%)"+(%+&+)*!")+#*(%+#*"+$"&#(+$%"()'!&"!!(+&&
@r1740
TTTTGTTGACTTCCATTGTTCATTCCACGGACAGAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGCCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATNGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATACCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCANGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTAGCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTGTCCGGNAACTGCTGTCTGGC
+
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
@r1741
GTCNAGNGAAATNGANNCCTNNNCNNCGATAGCCANGNNNGTGATGNTNCATANGCNGCTNGACTCGGNANGNNGNCCTCNNNNTNNNNNNANNCTNANNGNNGNNNNTGGCANTACNAATANNTTTANAANCTNNCTCCNCCNNNNNGTNTGNNTGNNTCTACAGNAGNCAGCTNNNNNNATNNNTAANCNCCANCNNNCACCGGNNTNTTGNTANGGNAANCNANNCCNGGTCNCTANCNNTCNNAGNCCNGGGTNAATNNGGNNNANTTGNNTNACGGATCNNCT
+
$$"#!"!$$"#$!##"#"##"!!#!$$#!$"$"#$"#!$!$#!!!"$#""!$"$!"!$#$$$"!!##"!"$$!$$!#"!""!$"#!!$$##!####!!"##!"#!$""#!!!"!##"$"!#"!!$$$#$$$$$#$!#""$"##"$!!"###!#"#!!#"#$##"#$!##$!###$!!#$#!!##"!!$#$"!!$#!"$$!#"$#"$#!$"#"#!#""!#$$!!#!#"$#!#"#!##$"$#$""!#""!!##"!$#"#$#!$"!$###!$!$$"$#"!"$!"""###!!
@r1742
GCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCANACAACCTCCTTAGTACATGCAACCATTNTCACCGCAAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAANAAAGAAACCATTN
+
0A,>FECE/D@"FB!639@9;.#;$,)7BG@4=$(E18:$B5(=A@AA8,$/-FAE9"9C(",(9%D$=(."F+'80G+')!7D+,"9?'::'C5)'3=D:B%4/&<4B>5A%22<G6H!E5A"6%5B935.B(/+,1!3;A%#=/))$;@1G+A@G1D1$
@r1743
GTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCC
+
C6*H4737#'++G>!$-420G2'&6D6E;DA<165*8"A#A7B$9=5$7,8.A2H#=2B&G;.=H,-!.+AD:4D7</.??B>77>F&3=22B!632GH7:'3B3@%E!=-D5DG%/822F$/<+@?12+$"0,A+6/CD%=09:C49H/*.8&A8F5GG(2B#9?//)*A#.3"&/86&!9?&!4+'$6"
@r1744
TNCAAGTNTATGNCTACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTNTAGTTTAAAAAATCTTTCGGCCTGCATGAATNGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTTCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATNACCGCCAGAGGTAAAATAGTCAACACGCANGGTGTTGGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAANGCATTAAATGCTTATAACGCCGCATTNCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGNTTAGTATGCAGCCGNCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGANTAGAACCTTTACCANAGGTGATGCGNAGAGATGGGTAAGCACAACCAAAAAAGCCAGGGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACNGCACCAACAGGCTCCAACTTTCCTGACGGAATGTTAATTCTCGTTGACCCTNAGCAGGCTGTTGAGCCANGTGATTTCTGCATAGCCAGACTTGGNGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCNCTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTAGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGANTGAAGAGACGTTTGGCTGATCGNCAA
+
%!**#%(!!)($#!"(*+#'$*%&!(#)!%(!$!'"'*#)$%)"+*!%'&+$$&!+%*+&()(&*'&(%&$")*''#(#!)'&)#"**"$*($#"'+&)+*(+&&')***(!%"'$!'&*(!)&%#&)&$#%*"**#+&**+#&'*$'&!$(%!&!''"*''#*)!(()*#$#'!)+"()+)+"+%##&#&''(!*'$"($*!&(*#%()"!%'")&%*&&()$&+&&!(+"%)"'&#')+"!!$!")$!&$#''(+)$!')%'$''$"!*%'"(!"&)!%'&)(!!&+)!'$#*+'()$+&!!&'(()(+""+#+("'&*")!$#*"!**!#($!*(&*#$'!""''#&&&%(*"*%*($*)$'(&$*+#&+&$#$$)"##"')#)+!!*)#))&"*')$(+&''($'$)%)*(!()$'%)%(%*("*'*&$+%%*")*(%+&)#)')#!*)"$(&##)#')&'+%%*$#!+'&#$$'#+%"&*''%*"'!')*)$)'*#*)*!#%$'%'"&(+'(%&"!++)"!***(%$+#'"##*%'(%((&&!'+%*&(#"&&+&*)"$+&*('&""+"+)))$%*&+!!&%!(')'+$"('#!(!)!*%&)')'(!%"%('#*(!%#(!&!+$')'*&!&*+$'+'!%&#'#!&$)#+&!%"(('!#!&'%!*'((!!+%("%'')+))$(")(!"((&%(&#')$($'!*%("#")+!!)(&+!**"")#")&#*!'#)#&"##')!%(+%)"!+('++$%$"!&+#*&!&&"#$#&"!!!&$!(%)($('+)!)$''$("&(%&#!(!&%"*!#"%''#+*(!!#&$%&#&'(+'(%!!!+%*+%#%#&*%()"%%)(*#%**+#%)"*%(#*"!*%%!'+$&(+)')&*$((+*!!"!(&'%&")"$")!+*#$(%!')&"&'#$#%&&+((#"&$!#!')%*(!%)''##("%**!+)"#'%"&+$#%##)"$&!*(*((#)$)'"!!&+*'&*"&'!"%'"'%#"*!"#&"#!')"!#&&'$%('$%"#$!)'))++((+"'(%%$&*##)+&&)"$)&+)$(&!+*%')%#%#*"*('('&!)*"%*!%+"%#'
@r1745
GAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGNTTACTCC
+
44DE(4:A2F&2&BA"2&:7B<A5.A99"4.H2:""-7>=",@B>>F2*,<"!<.CH9"#%7;3@2A+$873@?6CDB!G?*"'<6=22@%520:+65%30=6A*:E)&1#BF6<7FE/>G"<*A)DG76&*1!A"A=/*%#!<;)+57B1=5$:AD31#/<;<3H(;;,.8!F@.)>=5$E+&?CC4((%1#"63A%G8!C(G179FF<>/F6H):(!<=AH8%;*;903.&C#&>7FCE?A4;A$+E,?-90
@r1746
GCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCA
+
><D3%9:6C,<?A-<8&=!H?D8HBE&94@-7-;1F@:'(*7552+@F2;*79B.;?>DABG,/186&2<;D&B3=-@*B3-E@2!H(73):B)"=5E9?27@6/5::
@r1747
AACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTT
+
C3/?8EB4+&EGA;E3>7*<02D592+-@71"!.%#(@G=8F-'$';!E.75+.'E;/#9@C+B/C=2,B?8C$$0"+>
@r1748
GTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGNCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAAGGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTA
+
A(:H(4-:(@,?'>*E=C!):.8,0&A3':.&%=08!)@2<1"',+0&-20=9.;9#>@A<&@*-;>>52C60:03E'1G0!$3GBDC+G@%79'9.H4G/7-"G+4A?CC&546E>G';.70$<C?<;!;BD.8&1B.>:A$0"G*FC'0F80BBC7(#5G5&%"4>AA=<D<'>7:3<#/="<,G+E&,4(6-/%>C)/C>*D#0D6'!".;"%/EE2H(C!7%F-*23
@r1749
AAATGTGAGGACGCTATGCCTGTNCCAAATCCTACNATCCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGATCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACAGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCNGGAGAGCAGGGGCAGCAGGCGCTGATGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGANAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGNTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCAAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGANGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTNGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTNTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCNGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCNGGGATGTCATCCACGGAGTATGCCGACTGGNACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTANACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTAAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACANCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGNCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGNGATCACCCTGTCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGNGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAANCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGG
+
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
@r1750
AGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCANAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGCAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCNGCATCGCAGAGCAAA
+
AA?@!8#(>HH3(9399"+>6H/=F?24,&F:C;0,%%1?2F-2%58B?$9F#**3<&B"8=(9D)*99;?+5&1-B"5!'28'C:60GF2/+-37F&&0(>-@D*,8+DBA9(!85+=E@F@H8#%#>@G;4.+4BA'0+CB2/.)2$H011<>+C,,=!//.DB)AEE)=2B&F<>;B&*&#-41G,!:F?9"/1<DG3<.*;(9?8H93-#H1H;6DC#GD'.$/=C%543<",8>A1.?),B%C/:D15FD-54$#2&D(*!3F0%$5B7*:#.&"&5H#G&=.E"&%/C2@A+73.E+.>57%?3?+4&'EC-(;=7:<"GG*9+)D:GH='"<%;0@9@A=)AA6)F.'5-'FE$285(5<B11.!B%;'A7+;/%'25/A9+-#!F(4&0:(*)"'$D@3!EH;#*9B)$EF:D.%&>EC>&1?*HG/"2+",47;1-,8G&C'=1!)!*!974(6!&*&9>+$E<<-7@BE=2;B!+2E/=?G%#;+:4//C<(#7-'&107@1>#C@;)C#*C&;+>#?A=115%#)A,F(1<!CE.<%E4/)"EFB.1G&);H
@r1751
GAAGCAGTAAAAGCTCTTGGNGTCCTGAAACAGAAAGCCGCANAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATNGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAATACCCCGCTCCTGA
+
:)D(6B+A+%/+(DF4E<;7GH:&+A!&EC,D<G?6B'9%H#4?-?,-81$#&(G;$@E0>'1F-A$?,=!C(<E!@1E/%BB;/G)G9A::+.C5'"6<?:@F#>.+$2A.<;%C$H,%)2C*)HC*H(91C-9))839+/A?0<#*'@?=79,AC6;.60$50&4>;;C?55)5E=B,=;7E.<G)&,>6-!7:"?#7
@r1752
CNCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTNAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTNTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTGGGATTCTNGACTCGATAAGACTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAANTCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAA
+
%+17642*D3A$E++.D788D(F:,+;#5"516>0'!-!(369?1A6!#=E;%."A"GD#0.$<$F1@#/E"(),3">=2FEB;,+=<-D;1)*/@GFB!=+/E$$>E*9-BA1-<?G(/D#84$9@1#@65!E*?H&AB'79'3*'A3+2/@'<9C8&1@*:,?#-;5D3%(182<!)0F.&1=C2D+<6*1,'?&@B#3-G:1("8/ADDADAF58/B$5EG*E4C!>97--?>BC:;D40>GEHBF42".&9$"9:*"&%D*=9+9?%3"@14?=6!GE"5<+0E?F.(.73('A4*A'$=()5+(C*3<H>#D:/;+!!H%2/<.:3)2174#:D0((.:@C82.;<1+F/>=0?9D<4"E+:&=-H*5=*D.@2*
@r1753
TNTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCNTGANCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATNACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAANTAAAACAATTGCATGTCCAGAGCTCAT
+
(!&+#$"*'**+$&'$$#$!&)")%'!'"!"#"#(!(!#%''%)!()!+$%"&))'(+(!'$+'!$)%("$)#%(**&!+!*$'!"#')"#&(+#%&%#&'%*$')&#%#%&$$)$$(%)$"#(!&!!%*$!"&&"&$$)(&&!%()&#)'&+'%%)"*)#%(+&$#!$'(#$!+)$(+*!%%*"!#*")"$+*''')!'+*$'!%##"&'')+'&$##$&!&#+$'!&$#%!+)!#)**+(&+'&&#()'"&($)&%++#*"+"%'#(''+"*%%+)!)""+%)%*"(&''
@r1754
GACATGCAATTGTTTTATTTACTATCACNAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACNAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGANGCACGCAATCGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGANGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCATATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATGAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAANTAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCAACATGTCAGTTATTTACCTACGACAGGACACNCCCTCTTGAGCCTACAACCNTAGTAGTTGCTAACCTGACAAAGGTNAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTNGTGATATAGNACAAGCAAAAAATATAGATCATTTTCTT
+
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
@r1755
GNCTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTNACTGATTACTCCGNTCACCCTCGCAAACTNGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGAAGCTACCAGCTGCTTTCCAGTTGGTGGGATGCCTACCGCAAGCAGCTCGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCNGCAGATTAAGGAGCGTGNCNCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCNACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCACCGCTCTGGTTATCTCCATCATCGTCTGCCTGTCATGGNCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGNGACAAAAATGCCAGAGAACTGAAGCTGGCGAACNCGGCAATTACTGACATGGAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACAAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATNANGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACAACCGCCTCCGGCGTGGATAATGCAGCCTCCCNCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCCCTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGNGTTGCCCATATCGATGGGCAACTCATGCNNTGATTGTGAGCAATACACACGCGCTTCCAGCGGNGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAA
+
)!!#*)'*)+('$'&%!*#+*!*##&()"(!+!$'+#&##'()""+$"&!''%!!#($+++#!)#&'"((&$&'%(%)%""'*'#(*#&%"%$!#$"''%&#*)!!&)*)"*)*')!($$(!!%$"!")'&$(#""')%+&!#&!&+&(#)"#&#%'+*&)%#$*(%$$*!&))+*(#&()*"%%++$"''(++$"#*&(+$!!"'&()%(('#)'%()(+&$+'++()(!'#!!)'+&%"'%++$&$&("%$"#%+$#**)##%*'!%"(*)&)&%'"%'+$)&'&(&&%'&!*'%(#!!&!$"(+%!"#)&&&&'%%+$''"+&"''!'!"#%)+"#%+*('!*#!++)&+#+"$($$#!&)%%#"%&%(&'+%$(*')$()+!&'(!$*!!(*$%#(&&+%($"&'!#'&%)((&+'+'#*!"+&+!)!"*#("'!!**+)""+&%&"&!"+'"(#"*#''"'%&(*"$%$&&#!'##))!(&$"#'"*(+)(*&(!*!$*%#&**)#'#)+#&)$*+)!$'(#)!%*!$'*#*((''%%+)(')*&'*&"+$')(('+*)(#"&$*(#%)($+#(##$!+++$%#!#"'+$%*+(*%+++!#++)(+&('#($''%*)%'&((*'))*)"&"($&&"%))&)"$#%')**#(("!)%#%+'$""")&)#)#&$%('")$'"#'$#!+$&#$&$)$)*!''#+")$*#!%*('(**$%(&&"""*$$#'*%$))&%#""!&*&$'+&$)!**'%*!(%(!)+++'%&!*&#+!$!+!!((%'+#$)$"!(*%#)"(**+!(!'#&(&%)#((+%#$*%"!*(#()%**'&%#*&!*)"&(*%$)''%*"$!#&(+(("+*)#*((&)$&*'"(*%%%''##"+%(&")()#*$$!&"+&!$)"''+%$&$'!*!!#)$!$#()$#!*&*&"##'$")#!'+"&!"#!'#''$#$+$)*""(%'%(*&#&"!*$'!)&%%*%!#'&!!$$&%)'*"%&+()))()+%()%##)("$!#(%(!+*!+$!$)*")+'$"))&((!!%*""##!''#$&#+&**!#)'*%"%"+&!*%&('+(&%"(+"&**%(+*!*"'&&#)$&)+$!&")**%+%&%&&(#$&('"!)"
@r1756
AAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTANAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGTTGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAAGATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGANTAGCCTTTGCCTCGCTATACATTTCTAAATCGCATTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTNCTGTTCTTGCGGTTTGGAGGAA
+
293CH#=E>>3+00H/=$.B@E+=43!F/?D38"7;-5,8@3(":'B1;=(9F""8<"76,G'8?218A%7C&%%4<#(&H+F9&&#H:A));C::"';AA=6A8BC,!E1)G0G#"D14:&,464D5&+;G/CHG;-&D@*/*$>**1E9A="$D&2#D35D@$2*+<G7<<)C-/+B/@),A<E"-::G6B=?(277=)#:E9!;=F%AF%D,*E.6"*#*?%>35.C5<'D*=+6>E719E<C6,H91/0F?>=B4!&HG8"$.@&;$</;FH*8%G9-AH1?%E=59>%7E/E)*($@D33!'<EA'1B7!B-F-&!FE4##!07'CC'H&DC""B:9)D*)/EA$9$)A1,98)$1!@(,,3:(9$<6"F@6E-(:#8++;0B8+<G1<&*#@?0<$.-/*:*+#<B(7(*H=-7#:F3FE0*7?@H'96C(1%?93=6+5*>5)F:5:6$9,H5";6@#ED#+E'8
@r1757
TATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCNACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAATTTTTTATGATAAACAATTCCATCCANTTGATTTAATCAATACAACATTTGAAGATCAAGNAGAAAAATATATTT
+
D-/&3=%H2=HH:5$#73=G;GG9;:'19B>599($!9FGA+E8*=3%,#H/%E.F<+A'70F*1B/B6-<!7"5+#,/7?5(<D3=);F2530$C;76",GG=HFD"GC.$/*;=-H+"(A)D/"(.<D6)3C;6!(>5B*B1=H*65?>(>7&8DHBH&9<8@?-;'):6F&=ACF=.GAD'4H1A!+.&.F"$8C7C';9'@"C6?7!0#;#('#,$*B$
@r1758
AGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATNAGGTGGGATCTGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGNCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCNCTTCACGCCACGCGGGATGAACCTGTGNCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACNGGANGCGCTGTGGCTGATTTCGATAACCTGTTCGACGCTCCATTGCCCGCGCCGATGAAACGATANGCGGGTACATGGGAACGTCAGCCACCATTTCATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGANGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGG
+
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
@r1759
ACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTGTGAAAATATCNCCCGCGAAATGCTGGGCTGATTAGGAAAANAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCNACGGCTTNACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGGCTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTT
+
+!'(%(%%)!$+")!"*&"#+&+%'*))$%#!''''"$&'#*#+#)%&&*&$+*%%(!#)!$$&+"%'$$&+%("&'*'&%$+&))(%*+*+((')(')%&)"##')*''*"#"+("'+(&(&&%%(!)&(!+&")*+#))%&$)+)!(+$$%'!')"*&!"')+'"*$&*'"%*)&*%!*$%$**%*)%+%&$*))%)#%"'+"#*&)#++#*&##$&#)'&&+("$$)')+!%"#'+))$)!'$)+(%'&""&##**($'!!!+&$!(#*("*'%%'#+$"%(*(**#*'!%*!$"'"#$#&'$
@r1760
CAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATNNGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCGCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGNGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCAC
+
91B-2&6G'3&$,?3"&'%"9?@<@9(-A27-A8+'*7BF/5BB)9<";H049D*F0D<+,&7."B(,;7*6!=,>!82C5%@(>@("0DE*AA5"H+;GD5,%#H)4E0#E5">FF&/HD$F4A>5=H(B8"C@+!=#0%=*$>.6*1G36")45D0@6C*F-.GD,)H"2;*<<;0B-@;-E'1%F81)(=96+&";CBA;1*990!HDC!DC#1&&.,/?3?0>(#49/3=2*%))'3::;$>567F%D:)%2)<8?&;<%)$@01$7%A7DC3BAF7,;(2/'5@!=8#@'49+-<3?E5,?%,3<9%A#D7@9D!?5E*,
@r1761
TGTGGCGAGACAGCNACGAAGTATCACCGAAATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCNTCAACTACACGGCTCAACTGTGGGATATCCGGTGGCTAAGACGTCGTGCGNGGAAAACAAGGTGATTGACCAACATCGAAGTTACGAANAACAAAGCGTCGAGGGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGA
+
#5A:%F)=9/)E/4D"?"$6A=G(.?D7E56DF/(%F4(-B7"&831&&.8/!*/HHH9!.E=*+/380F.<10'(2"FF4"*<<H?389(;(F9/.F*E.D'@"&?70%#*#=DEE+6A@E13,8*$/<+-C+B?4;&:'E1&?$G?:2!6,*9A#B')74%"1'3CH=1D:,HHGF#$#!'3753<,*6/D&HA928)-2B95((?1&EA!!-'1&2=B>2>!%!@+G!:%./=,00D'<))?9#1-G%%'*349A4&#$'(#>8A'7B@;>39<5,D05;;60/&(B@$3,5='7/.%3":'DF26)#
@r1762
TNNTNTCNGNGCATCCACGCCAGCGTGAAGCTGGTATNTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCNGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTAAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCNCTCCCCTTATAAANCCACAGGNTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACAT
+
&#!)"#($%$+!**)$!+*'''!(%&(%##)*&$'$(()'!*'%'*%%#%!+&+!*&"(&#$#'+++'!+$+&&$++)#"*!!'&)+'!%$*+!*&+**$$%+#!*$''#+!)'&"$*#(&&'*!&(!&'%$**'!*)+"%$%&'#+$#&+$&&$'!")%+&"%&*%$(%)*$"$$!)!++$))"&'+"!+&"!&&$"$(+)"!#+)!++'"!$('#"*++%#%$++#$'+"#'*')+%*&'++!#"#$+'!!#&)(#%$%!#()&)*!*"$$)!+*"%!#&)""
@r1763
GCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGCGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTAAGACTGGAAAGCATCAATAGAAATTGAAATCGAC
+
A$'C;()+8A!4-(60$@$?%=53*$.G03.G*'-$'A;$%=.3>H.:5E+B=1>>E87FA;5/?$>#$93FC-1#)/9=?<G=#5>08<;%GD-67::52!EG(8A!/,(%
@r1764
TCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGG
+
/*?F%)@$$$F8$E-+C5425?<G+&F*&&@-=@-6:">B$09#:!A?,$;(.#00%1!$;@.G9/DD61!#1$+9$;G=
@r1765
TGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATC
+
4D?1<A9F36E1?-#>?90'</4!0!98'.-&9@%#64=$%1.!#+4A800-3723/>D5)3"#14C%E'+$
@r1766
NGAGGNANNATNGTNNCGCAGGGCTNNCNNATCNTNTNNTNCNNCNNTNAGANCNNNNNGNAATTNTNNANNNNGNTCNCTNANNTNNCNCCGATNCANCTAANGTGAANTAGGNGTGGCANNNGCCNNNCNCAGNTCNTTNNCNTTNGNANTNNGCNGCNTTNNGTNGNNNNNNGNNNNNNNNNGACNNNNNTTNNNANNGTCCNGCGNCNNTNNANCAGNNNCNATNNCCATNNCGCAGATNNNNGANNTGANGCTGNACNNNCNACNANNNCGNGNGNNGNNCCGNNNCTNGTNTTGNNGTACNATCTNCNGNTNCCCGNTTTNTNNTNNNCNNGCN
+
"$!$$$$!#!"$$$!$#$##$"!!"!#"$#$"$#""$!#$!$#"$##$##!!#$!$""$"$$$"$""$#$!$"!$!!$#"!$$#$$!!$$#"#$""$#!$!$$"$!""$#"!$!"##!#$!!!!""#!#""$##$$"!#$$"!!""!#"$!!$#"#$"$!!""""$$!#"!$"#"$!##$!#"$"##"$$"$$!"$"!##!!$"#$!"$"!"$#"""!#$!##!!"$$"!$#$!#"$!!$#"""!#$#""!#"##!"##!"!#"###$$#"!$$#$$!$!!$"!$###$$!###$$"!$$#"!#"!$"!$$"!!#$$$"#"#!!$#!$$"""""$!$#!"
@r1767
GCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGC
+
.%0>.;F2@"<C'-%&===/5$:*+))B#6BF+G&")<D10$HG;1=G/:5)%+&.*EG
@r1768
TATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATNGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATG
+
C$+?"(//;#.;)$1#*H,-/E17+/1'>A:D"B;:>);=;5H4H8@4G'FCA#-/#+)&A+3>DC?0"8?208H(G0443B&4G%@;=)F'C;"E/@<52+25%2,@H$&D@>="@F#>:/:>#9F">!A.4F'9GB5)9'5A<$2!$5"FDH@%D8C"+.)D$(7AA3HB?C29B,:(&,,2@$94:1?)G9D=C;B97(&7F1-/(1G8&'/
@r1769
CTGCCGGNNAGGNCNGCNNCTNTCTNCATCNNCNNAANCNCNTNCNNATNNNNNCGNNGTGNNNGNNGANCNNAANNCNGNNNNTNCAATTCGCGANCGANGAAATCNNANNNNNNTANTNCATGNNNNAGCCTNNNNNNGNACGCGNCNTNCANNNCNTNNTNNCANNANTNGNGTCNGTANAANNNNCNNNANNNNNNATNNTNNGTGGGCGAAGNNNNNNNNNGGNGGGNNNNNNAGANGNNNNGNCCGAAANCNNNNGCTNGNNGCACNGNNGANCTNGNCTGNCNATCNTGNANNNTCACNNGGNAGNNNNGTCANNTNGNACGNCNNNCNATAGCTGGTCCGCNGNNNNCTTNNTCNCACNNTTNNNNANGCNTNGCAGNGGANNNACNGNATTNNNNGNATNNNNACGNGTNNCNNNGGGCCNGGTNNNCNGGNCTNCATGGCGNAT
+
$!$$$$#!"#$""$!$"#$$"#"""$$#$"!!#!"#"!#"$$##""$""!$#!#"##"#"####$#"$#!!"!$$#"!!"!#$$##"!""#!!"$$##$!"$#"$"""!#$#$!!!!$""#$#$#!"!#$$!$!$$!!$!#!$"!!$!"!$"#$!!!$!#"#"#""#$####$""$!#"#!"$$#!!$#"#!$!!"!!##"$"!#!$$#$#!$#"$#!!"!!$$"#$##!"$!!!!!$$#!"###""#!$#"$#""$"!"#"$!#"!"$"#!!$#"#"""$!$$$"!""""##"#"!$$"$#$"$#"!$"$#"$!$!!"###!""#"#""###!#!$!""#!###"##!"""##!!$!!"$$#$##"!"!!$!$!"!$"#!"$""""$!#!"$$"!!!$##!"!$#$"""$##!#"$#""$!!!"$###$$"#!!$"""#"$$!#$""$!!#$"
@r1770
NAGCTGCATATAGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTAAGAGCTGGATGCGTGGANGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGGCANTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGNGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAANCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGNGAACTGANCGCTGAGTCCTATGACGACAGCTATCTCGAAGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGNAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACNGCACGGTCGATGTGTTCCGTGGCTGAGTCAGCAGTATCGGTATGGCGGTGACGG
+
+$!$!"&*$&!)#&#)"!*+!)+('"$&"$'+&$%+*)(#"$+#$&'(*!%#(##''"*&""'%'%!!$###&'$#$)$"!#"!++'&'"'*&+)!)'+&%($*')'"$&&$!!*("+#'+(%&'#($$%(!"$*"!'&&"*')*'%(!+!"%')%%*$**$+*&&!$*(&"!"+*!'('**($+*'&)*&"('!&%%")($$)#())!+%#*#+)*%#($#%'%(*+)"$*"""*%"(+''#*%!"%%$(#*$*$+!&)&$+#)+'*%&(+!!%$&#+"*#)%('!#)'#)'$")%!$+)&"$"'#(%&$*)&++'$)()*)$$)*%%$!#!#**)%+#%$&$**&('+&!$'((")$#("+)$%+%%"(*+'&$$$"(*%')&#'))'%%'!)!(%$%'*&##('%&&&*+(%%"#*+%$'))(($(!+"$*(''*+&#!($&&&!)&&')+%((%&+!"+*)$)"&"#(%'(("'%'%%&!$%&('"*)$#%#%$*%##')+!#"$(')#$'(**%"%+%+("&+#+*)%&"'%')!'($()"+)(!!"""$#!'($$%%!$!"#$!**'($"++%)'(%++!)"$&((&!")**&(('#&&&(&%(#$)&****&(
@r1771
CCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCCCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGNCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCC
+
;3+82273A?/1>>2<G*CB#61H2B%*:;4#+@%F;1E&''3C7-A+'104*3">4'(/+>/,>C3;B!F/5D&?7!+1"$.BE"*A1F$4?06(CE;1$=3891&-#*)$A5DA!0G%C5*3?E'2>!=$1;*394:;("@@B14421?E"0$0B1)H964#H+*4>#$C2F+&@&*%6;))DB"-=+@8+F6$847'1$0;=7*E=2<)E%AF5")5<%DA)BEF(*!3=;9',93=,!-C56F4;"F0C!AF?C9$+:(9+>D3&;3HG38CE56)-;;),CF;=.HEA+,+8+#$3)F0)%.".(C(6BD-*-")C>AA>+3";D172;EH9+$34AD?0H2!*C!5
@r1772
ATCGCGAAAATGTATTCAGAAAAGGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAANAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCAT
+
947'G!@FB29B:$"E2?B58,&%H@>+-<7D3#$$,<72-AA8%'#,!11"3H#)1)HD/-&G%9)@04+F(*9&!B!H2A=%,#H;G3$5DA=B;38#D:E8F,!(,='+A&BA&5BE''H=/8431'?H+BG$,E4,H,B<'
@r1773
GCNGCCCGGATTAAAATGCTNCAGCCGCNCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAANTTCCTGATAGTCGTCACCGCGTTTTG
+
0@1F#&!,<3=8F*:)+3?39!98B!A"2*<D)9!B"(A-&G%EC6.19<B&+0?-*0$6D,(:%D()="F.D"<?H2")"0G998B=-0/*1-B<!!?!C0;=2BE3H44.*""!!AD/
@r1774
TGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGNAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAANAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCNTATCACAAAACGATTACTCCATAACAAGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGTCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCC
+
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
@r1775
TTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATCTCCAGTTGCTANCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGNAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCGGAAACGTTGCGGTTGAACTATATNTCCTTATAACTTTTACGAAAGAGTTTCTTT
+
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
@r1776
GCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGANTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCNGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGTCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAACACGGTGTGACGGACTGTTACACACTGTTCCGGGATGNTTATCATCTG
+
C1G.5?;.D8@B1.:3+BH'%>BHD?>2D$C-$!,B?44@1B+2B'*13GH0G8%F3#989);37G*)31+./==1)?=1F6,>77HH9HE4"74,D9H;>.D8)C@'*));=@?&8,D,8&($F'*@91!:(.;.010;$96B+/:&&'?4,".(-,*A88H:7+#B1**5;5./.@2G"G(+AC%0'(H0!@.,6'?:32HD:*F%B5.605C83;>1)8@$65"BA5#160G.4,20!934(3=.E7&*#C>>/*!4.642'$3/-C.6>C?%@*39E+,7&FA!(5)/(!DDC(@F9%1>&:C,4GD/&<&''+&5+E:0(44FA'BAH9.0*",7%C5A7D>6-E/>*1:8+A>?:)):<A-;%!A@;0G+F!F4&'3-#+C2=#FD*-&"F47FC9))D=9/A:%GD,-1FF1:#C8#:!
@r1777
ACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTNACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGA
+
.F>965:G%0C;!9*#,(C75$,!>1259D<)$.)%7'=<2>"-?(66?;F6;2/4!7H+98C>)//)1&37C13G*00:D6.<$A56*!'?F0."$2GA/''B:((G)-8@9%:(!+@*1C2B#)6691<A&"4<"57&)0"!F::&%8@%E>->6)>:CA:G<<$@C/;1.7$*0/B8-D'"A25E3HE!C%"&@?!;.81'BCH91
@r1778
GCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGANAACGCCCAATCNTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTT
+
(>B<262A;6,6&66'//4'>.%56=H:?HE>89'!247*,%H=H2'&A=4,$B&4!23)*>:.:)GF.+G2'H3&6=+H=@3B2*5'B,"":"<(3,1!1>7CB)/-"!E?(0E%=1AB6E'@?+8:;?-H"+6#8<F3A;(*7(?/B14564@=FF#,=/!6"4&459,H)(:<6*15-BHA=A!3'FB<5&4:3564-%*9A:#"6E,E;?H(E<<B>4+?*F><*9!B#?.AF)28GBF-C4!FA4:C0(#(6C//C)@2C&=A&B/!9F>;+@18=%6D>5E%C(A319:642B?(@,'H:"#B)?'@#1E45)!&>3*1?D#9G(6H51G8-H<=98?"AG#9H;FA;0C?C
@r1779
CTCACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTT
+
#"<?<;?8B&6"1=(H20932'40!76)B!2$+@G>:1A4A&0=3+*AC%'
@r1780
TCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGANTC
+
;5'11B1@F#GE9&?:)%B;C&D)1,A2@@%23'0+E'6C)7?<:F>$H;-
@r1781
CCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCCTACTA
+
B-,<8$0%-#8>1DB#?):&G36'</"$2G#=%0)ED#H$"**&/432A'EE,?36/>>*"("
@r1782
GANGCTATCNGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGNATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCATAATCTGGCGTACCCGGCTTACCGCCGNCGTCGCATCAGCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGTTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACGCCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCCGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCNAA
+
*)!)"'$"'#(&'+)'"#)*'"'+#%!))$''"%!(&)*)"&!+$#'"'&$+$$"#!++*'%"(%#"#+"#'!)"(&"#!!($&&!%+"')"(''"+"%&#&##!(*"&"(&!'%&$+)(#$%(*")&'('%#*&(+"#$&)"*('($&+%$%&#$%!!!(("(+)+$)%+&"()+%*$#'%'&%**$'"$%*&(+#+$&%!))('"*'!"#!'#*&"!$*'%'+#'+'%$+!*%"""&)$&!+"*#'#$*)#!+"(#+$%$)**#$$!**%%+*##(&%''#$*'+**&'$!!!&"&!*%$)(%%("&)%)*%+)&((#%!$!#!+#'&%(!'&))*!(*#&%+!$$+#+(&%*'$"$+%%+!!%*&($#$)"$
@r1783
GCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTNATATACTTCTGGGTTCCTTCCAG
+
F.67*%-?#-C78%32.A&<9G.*/'BA$F?:80&A-3$GFDC<H>AB#"*43G!-6';B(A+?0;(.,EE6="E3(-=3%-F/;=G0;@,561)DB>=G03",>75#9<#,(G)*E
@r1784
TGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAG
+
H.<E:BB;;*#!$(5+A5GG-47&3:<&.9<&+HHF-*$215"E1E+<)1E8"#76>'D8$,EHHHBC@*DB""C+?62DHA4#$%(1B1*CD8!=(##2*?$GCGHD&E#1!@5-'G7;&:3A...@,=/E:7BB3)&7%*<26HHE32(DC=,2'-";!1E;@6+/!H,'?#/72#4
@r1785
ATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGGCNACTATGACCCGCGTATGAAGCGTNAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTNTGACGAGATCGTGCCGGAGTTCGTCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCANGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTNCCGGCCTTTCTGTTATCCGAAATCCACTGATAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCG
+
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
@r1786
TGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGNATAACATGGTTGCCCAGGNCAATGTTCTGCCNGTTCTGTNCGGGGAAATGCGCGTGGGGTCACGGGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTC
+
*A2H;4.3:4#?*.=.&=./,-?)7>,C2.5<-4#$9,C*701;'7>)*>7+!,G)=+<HG1D.D)"'B79.*$G8.*$<G5GG'5)5>1E29:!E6C+D:!"<:/BA4-);B,1146G;:#<C<$G98FC:FF322''70'G833&29;-,$')<-3')>F?/>+#(.)$;$@0,7/25!%,?&8?C$+$-GD-1G63/,%468$B7756G6(-E:0C+)677)6F#7E1/,'0!,$E($"GF6"D$D2?D>=D/8=D%*'(7"4$)3==4(')=C)/#$+@9)(>;-82#+8,0%%)
@r1787
NCAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCNNCTGATGATCNCTCCNTGGATCTGATTCGTGGAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTG
+
?%D)B!(,0G>-:DF;),37(:**"H<#;8A6:,21-0616@941@9@C63=$AC00#%*FD@9@G'*#=>74.9GE&9&A1,@@B$@6DC#5:4<>H=<$)*.1?;$/?C6!>&)/1=29<,B5E45,3<G*'0D0./0B3,!6@+(,9A8:3B6:"&'"(H4(!<0/B>&-9?(-'*8C0),2"$+*"G49?CA9.(8>3)91@$>65"?@%6-,'%2027G%%4-"H7.<,F/1>G>F4%7@7F
@r1788
TCATTGGATATAGTNATTAAGCCAAAATTTAAAAGGGATATA
+
:">A16.E.088>.B(E9B=0DECBE:3);!"#-'455#$7G
@r1789
GCCANCCCACGCAACCAGCNTACGGCTGGAGGTGTCCAGCATCNGCGGGGTNATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGANCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTAT
+
:-(=);967GA7D#<F"/C+*79'62-;>E%$47(H0#'#E?8/)8&9A0?D)31E%<+?'@F8/!!)(E?4&,5?0>$+:7$>4:*C8@9@*;+B=,-(1:,?/<;+",F,B1*!%0@3H9-0;:$-EG.-7AEF>2@@8D(
@r1790
CACTNCCGGNNCGGATGTTACTGAATCCCCGANCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTNAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTC
+
*'#&#*'%*!&%'+%)!'"'&**$!*$'*"+"!'!$#*&#!*!&$&)"*%!*)'&&%&*+#('%"++)(+)&)!%$++)&$*"+%"(*)+'++!!+&")%'$'(*'*''&((")%(+*)%$&"+"#%&""%!&'%%"(!!%$$&''%#$("
@r1791
TGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTNAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACNCTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGNCGGTCACCTNGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGNATGGCGGAAGATATGCAGNGTCTGGTCNGCGGAACGGTGGTCCGGCGTAAGGTTTACGCNCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGG
+
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
@r1792
AAGNNNTGTAGCNGTATCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAANCTGTAGCGGAACGGCGCGCCATCATCCGGNATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAG
+
(*)!$&*(&!#%")(+*#")()$!+!"+'!#*##)%(#"!')+'&*!(%'*%$&!"+#"#%'+'$##"*(%!'*)"*!&#"!$!#$$$#!**&$#)'%&&&!$*"++*(!"%""#&"'%)()!')"(%)*!""*!$)%$$""!$&&*)%)'&)**(%%!(('*$*))!$*$*($#*$$&'!#+*'!))"+!#'")'#)$")%+%$'&&#+$%#!)#)%!+#+)!+'&)#+!&$$+(&!"+&$#'&*%''+!###*$')&$$!!$'*&&&)*(&($$$
@r1793
NGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGNAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTNGTTATCGGCCGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGTAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGNTGCTGCAGATC
+
")*$*%)+$*&**"$#$+'(""*(%+)&&)'$+))%))!(*")'&"*+"#"+$(!(!($$&+(#+(!'$%$($*)+((&#('"+#)#*'!"$!%+%"$$!()!'%%)&$'$#*!#(+(!!%**&#'$))"*'%&*(+*"#!+%'#"""&*%*"#!)+))"%)+'!%*+$**$+*"#))(''#$$*)%%&&&!#('")$&!(+$!+*$"$%'+!*%#')"%&#(++%#&)(!$*&$+"&$+(!*#*&#'*")%!+!*'("(%#(&#(*!"&&(%$+("&&'+*(&(+"(!'"+$#%!+&*#'"'&'++*+($#&(&")'*+!))&()*')''&##+(*'++'$%)&'")!"#*)+%"("+!#*$)#$$)'%#)*"!$')*&$'+)')&'&$$&#""'!%!%)%#""*&)%"'$(!()')!%'&'+)"&(
@r1794
GANGGAAATCACTCCCGGGTATCTGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAANCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCA
+
&')+)(%!*("%'"!+("(!#&&%(%'%*)$*+$&$#+##*!!()!'!$%#)!!!#"*()$$!)""(*)++"!$(**+#'!(%+""*))()$*("&"!+&"&"$""%%*#&!'$(%#"(*'$%+')#)""&#$*%*')#(**(&!"%&"
@r1795
NNGGNACCCNCANTATCNNNNNNANCGCNTNNANGCANTNNTNNTNCTNNCCNCNCNATCATNNCANGNNCANTNACAGNNGNNCNNNTCNNNNNNGGTNNATCGNCNGNAANNNNTNCTANNNGNCNTGNNCANANANNAANNCTTNNCTCAGNNGNNCGGNCNGCCNNGCTNNCTTANCA
+
!$!#"""$$#!#"!"$#!#"!""$$"""#!###!$"#"!#!"!#!""$$!##$$"$!#""!"!!"#$#"!#$!"!""$"$!#$#"!!"!#$#!$"!$"$!!"#"#"##$"##$$#!$""#!##"!!!!#$!#$"$!!""#$#$"#$$$!"##!$"!"!$$$##"!$###$"#"!!##!!$#"
@r1796
TGAAGGCTCCAGCCCGTNCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAANGGGGGATGTATGGNCATNANAGGGCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGT
+
*73(A)GH-&)&&5'35G:B<BE;>G%E-1<);AE"A6/(4@=;A33"E54D5B51G223@3)(9',)0=2.=E&=2)FF1@5E@./#<4$>0.!8(:!G18@.77:,FHD>9<>0.#-%D#EC1>%77<=;/$$):#.H&@(EE,:;6A?360@*+'>*))%).0,0,!$>E7>B1:78<E06'=2D%&B99E&;E-,%%17B2&(&386=2!53$:<*?.%.B&;94(!0)?!FE"5;5$D4+:'2$2E47$&"8+!>
@r1797
TNCGCCCNGNNNGGNGGAGGCTGCATTATCCACGCCGGAGGCNGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCC
+
#$)'$*)%((!!%)$+%#'(%((''*('+&+&)*+!*)(#)!))%"(#&$$$&%)"&"!&+%&%&)+)%&!$%*'&')+!'")#%%)%*'&(+!!&'"&"(((&&#%)+*%'(&#%''*$"(#')&!'%&")&#!'*+%%!()%)$%)('+$&$
@r1798
GTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACNTATTATAGATTTGAATGACTTCCCCAATTATTGGAA
+
-E*B=$>!B@<),H:(:).H1:%0F*&G@!,D=9@-<G3DAC%*60)65<7=#@4B?=+*G8EH5&6/-C)+HC1G?C:3.!3#=-B%7+*==*1A2,0=>$2CH9D39AG2&B861'B9"$1<$*':$3E6*:F2.@+E
@r1799
CGNTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATAGCNACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGAGCTGAGNAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGNTTCTGCGGATCTTCATCCGGCAGGCNACGCAGGGTCATCTGCGGATTCACTTCNTGCTTCGGCNTGACATATCCGGGCGTAAAATCAGAGGAGGAGCCGCCACGGGAACGGATNACCTCACCGNAAACAATCGGCGAAGCGTACAGCGCCATGTTTACCAGCCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATT
+
:@<<G0%3G!6@4H.(&>?$(:>$,"A%F@)B?2?@G<F6A/:F<64C9#%@,;=B;@0@CCA%@79E!2#&D?,-&?!?(1#=F)$H8,#H21)%H:HF(?%63,%"9/?$AG!G3CH0#?H4B3H$@<=.E(4.@>FG:%"3C;1/.*@G2.'A$04%:/AF/0(%84DG562C/C;0'#->,<2E75*8)>B.=8F(C+G!@;'&#71#=*H6:F1CEH<=@:</95((&/E<3'"-371-3<:;B.>-/4,HE2,11)'E>>62?6'3A7?4&--H!#)>1!*,$5?$:((#B;'->G/,);<EA1<-&<+8!<-+G+A,.2<#2+D3(B%)0*EG"3/$9C,1H35,.<*C7D8FE09G8%33;).)1.!(6>24E"A9A4B:?<8(A;!5.4*1?--;)A+-24&>344**=1G-D3;G>39H'(H=$/496,/<;H&"&B=>'"AC!89!:6,=2@*3A3@B,6-/4=&F20G7#
@r1800
CAGGCGAATCGCAATCACTGAAGCTATACAGGCCAANATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTCACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAANTACATGAGCAAAATTAAAGCAATCAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAA
+
E)*:57D(A<EB0%50E>'B=%F18*A6(@-1EEBFB6.*%@/.%A7+$,2?=G>D0?34?==&';"H))7?$H350'(#G!8:?>2@8@>(?6&;,FAB6";&+2(;3)B12CE61F5:&=0-;H4*E-8D!/0'@,)->;@3F.@31##D$*-+?")4F0;E+#$$"8-500=>!H0-1B-")+-6.64:&H3.+:6%G.+A4%/@72.0;&GEF6A"))";:"+E3E50':>;F#H&'(E9H=(&G$8E1HG&>6;7*%5-:B;#0#)FH!3"?9+="3,).!'G405DE8*,+@<&)2<$?(43+3?D6E1)"5??=+;=$C#G$&E=8+B@/*:H>+BC"'98?8$%@)!)-079H<
@r1801
TTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAA
+
)7993(;1;<2<==B"G2'53,-(-6=!HHC-;///%EA#C5C:EG>04E:6:$09$=?$8:89A!&@:,A?)("0D"%"9/(-
@r1802
CGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTTGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGNAGCAGACTCAACAGGACAAAAATG
+
/%6/@8"+-,.$+)1)$C(4"?'1'0'0@%+@11+/6HBF&*&4/DC7267?C"14F7C2F=DG77)30:G6$((14>)(/H=/->061/%:D04>=>@,22*G35G3#2'4C!#3C"$E2#80<?F0D6/#?*2,..4"8CDA7+D&0;"C-!4G(&+)2?,)?D!B4(F#8>+0%(F*:$A=<&E3D>(B/-22?9,9E48'*1-B"*954,,$0(E.$3C-H)D3/+006;,<3C!.!25#%7G92#FD4%+*@5@D%F2*+!EHC$E45/<H;(<=!"#6%*D>/87GF7980%99(9+A&("%$C8F=EB#A*C/=%12=?
@r1803
GGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGNAAA
+
"7-)48!GH)EA"$<-6CC";B&,1.F-C/@+2'<*(*4E@!?=5<EH!!>&*)1.>=:(%?2,G=-G9:#92>A-G@<$&>B%(-F5A$'@%H=)B<32)F;CH=:2B=A)CED5"334@#$@CA:!3<&%11*/!!%>A7G);G+-!H)/""$1#+D3@2?/9EH2.+;A"6G8$GD";)&H15H*#5
@r1804
ATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTNTTTACCTGCGACATACTGTCCGTGGCGCTCTNTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCA
+
(+$!%+)"$!"$%*#"'!!#*#*&$!$%$$!$*#'''#%&($'!&(#$(*$'($$"!!%%&#%(#)+*%#$+(%)*$%(((%%*"&#&(#'(%)$*+#'"+(#)*'!%*%!%#*+'#"!)"#(&()"(")*(##$'!**$+'%%"$!&%((%$'("'&#+(++"'!%(*&&!((&!(&+"($'"
@r1805
NGTAATACACCGTTCGGCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGNTG
+
(A'**?F<95'C&$6@;/46?:08/61>G*.2&C+8"A;.,,!<<4FE;9&$#:5;EB-(,AC-&5,88:>%/8'?D8F;5?"=%D28<6<"#
@r1806
TTGATCTGACCGAAGCGCAGCAGCTGNCTGCTGAAGAGCNGGTCGAAAAATGGGTGGATGGCAGGAAAA
+
04-1C1F5:HF.07/&0<!9D<D>"$>8>"9)2)6/%:0'+,.$<925+:&D@6<;4/#.BBF(?4930
@r1807
GGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTACTGTNAACAAGTTCATCAGCCAGTCCGGCATCAATGGCATCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACNCCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGGTGTAAATC
+
3+:(<4*>1B,,-=$@B>&'7+?(*@78>,"48'@?#?-(3/&:8/084G:-.B(/0+<%C4)-$"F,B57!)77"0'?C74A8D"-E6%23E#E&A0E*,).?2H%7*G&>@.*)+:G@%G@+020&)5;5#&-/F3>(6H6%6'!*@/(8E:H(.-"@8FF?7"E>-6<4D38#,?8D3)#"C2!6;8:&23!BD9=G1>%0>&7*3EF*GH1(</$-2?H)62"@:&2>B#&<326,..DB!45)**<4/;$!HF;-1(?=;66"8,)3"E:?-6B)B=>;5>-1'#/3C0B;H#B67:C-@/,6?@<.F#)B?B:!9H>D;%7C6&)@<?>.)FB223!G#FC;;'!@91>5!:6-0H923"D$B3#C6>G4&"0>$"H4F8B2F>BC56>0)>'D>:BE1*:@B9F70>("-?)6-#33;C16('C!*:-!0C;15>A-"('<C&8&3F8-C-5A?
@r1808
GTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTT
+
F:5!;F'!8$A+E6=)%+*GB%5B!A;HD'02EH@4,))?07(E<C:&96"/
@r1809
NTNANCGNGNNNCGCTATTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGCGTAGTTGGCGATCTGCACGGATGGTNCACGAACCTGTTGAAC
+
#&$&'!)&)"&!+*$+%!"#+*%&+!+!+!+'#*+*"($)''+)%&*('(+$+%%%+$+*#&(!!!'!$+"((!('&"%**(!$+#+$!)+#"#$&'*
@r1810
CGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATNGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTT
+
F>'&D8>798H(D:AAGH;=4A-";>@4+:36$=1%>)3';E;;><F1<AG26/B@*8@B!8$<#C8F='DBE#-C?&'C8236?>*70*<,5/:)540=8%H=;&"/+;9268&#AE#F2;F=A90%>'?F"))H2/6:F90..'2AE:>=-.<6>86&96@$@*>6*'D@@
@r1811
CAGTTTCANTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTT
+
G)>3:2H=?*6G&+-$<DFD57-%$+B>D4,$8E%6C5F01&("B5;;8)FD)6C3#!
@r1812
GTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATG
+
23A65(G:G-D"5(?*<*:@!*$./(/5G./:5.)&G"=.!!#A3E+7'-
@r1813
TCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCANG
+
0=<1<GBA:)5*0BHDCHD.H(==?$9#-(&:E&H+8?B='?D%D:#:D,1H%(E&A*&H@8'13(?G';/D=F%@H4;D->G,:A,&(!A.9+))A+'EB?2)0BD(*3";B&-9%#E29=>6#&+11:+$BF#91)D%1FH2%)3?(1#/#.'2.*4E#/>A<&7=%;!H67DE1C@B91>FG7A-
@r1814
AGCNTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCNGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGCGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTGTTTTTGACGCCGTTTTCCACGTACTGNCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGC
+
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
@r1815
TGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGNATTATGGCGGTC
+
E('B+'B)03'F:88*4&H*)".25$A-H&=716A"F'#'E$&$A*%/7%-!HB!65#6%7%0C,);*7%A;-F?E9F!(+D00CB0-
@r1816
TGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAAT
+
8&74"'E82B!/F*E/=87'?%C.68+:-!$$(.$"";*HF*8:E<17.F)
@r1817
GCGCACATCGTTGCGTCGNTTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGANGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGNTTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACNTCCTGCCACCCGCTTNCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATNACCTGNGAACTGTTGCGGGATTGCATTTTGCAGACCTCTCTGCTTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGNCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCNCACTACCACAA
+
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
@r1818
TCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGNTTTTTTATACTAAGTTGGCATTATAAAAAGGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTNTCAGTCAAAATAAAATCATTATTTGA
+
?='H9'=9,81!,E(>9G&'"H>5+*G#5-H#3'61$72G2H!1%$*-+E2&-C1G:$,HB&&;:D7$?'B-7=-<!*B3$GH-&.D24GC<E6?9?>G$CG.:58&:#GH4H=8C4!5>#%?45G0:?GH)+?,66"
@r1819
CCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGNATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAANGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCT
+
(CC=@)?:@8)(0+6H>/16)D$+,-)1AE':F8+?0=-B!EF0%%46+9C%'7F6)9>,5",9.D9&FB7?'-(/H-"-!"6;=CG"9*5=D<@:D9/:&E;9-:.)6,19)G0)E!H2#C7H53H9=F7&"8=5@>F,&CB;+>#<A(?/3B73#577H4!B0G=5#H+-.2(&9,"*-6GGC38-BB**9>/(AG@,;%!.3'&<$,?$"@@2=H;9/"8-"?40BD-G=B+4<?418H/8'$CB?51$*@D@*5A46(8C495923@=)89C457%1+;.!>ABE&?-H,''8,-0$))@#),:$;?.A#F9*F4@H%.<3=D2&B96*,D>G9?;1
@r1820
TCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATNAAGCAGCCAGTGATTAACGT
+
<)791A+#B"+%(<,#"90A(?-B>%9@'"@'>EAD06="B;<&/2>*.::)'3@/90EB%(:$>:,8CG),#/5<$7".?.A#<="5.#9<8-,3,BE$#C+-B8E8-.35>E"
@r1821
TGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGA
+
CB7#>;!;(4'2734?>*9?&BC!("25F3&A5()<%<!*6$9>,9.)<AG=G-0?-:5.+H5,3<6$#%"?$/F
@r1822
AAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTC
+
!-7$$0&+;(#3F<%<H<9EBH%2<11+.E$8;B-6>4%D"F
@r1823
NTTNTNNANGANNACNNCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCANAACATCATGAAAATAATGGGTACNGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGNCAAGCATGGCANGCCAGT
+
**)#)#!&"$%""&$'!+#(&$+!!$(+*$&'%')#(&($&$$'"#(*%$($*&"$*"''*$%'*)&'(%&(*+#!(!+)##%%#%+%$(((*""%)#'!%'#*#''"&(%%'("*&%$+"$%&"%!%$$!%'*!%*+#&))'("'!$)$$!*'%)"#)+'%)&%$$%#!&!$(($+*#+($$()"*%&'(*%#*%+('!%)%*#&$(")#%($#'*$('!
@r1824
GGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCNGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATC
+
,,2)D%>%@#',)$-"<AC+&$%')3G1.2#AC(E.:5+!50+D1E#"BHB0()@:?<!><4G3(!-9-0?F'".G,D(4#;/$0:H?E>$H1;CG3=#E))(B8=')22&<;H$C(701'&1?-1:5F$(26AF5B<59=-67(+C:7/!*3D;)$"
@r1825
AAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTNTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAANTG
+
51C4A@CC&>>0C#CF#?.!G*84.%(>(HEA!))$3ED@,;B,;7205G%6?(8?G5?HD&"5DHGD6D%9.:!%(+13%-5!'&-++0D+A9$+)4'%&-86"04=H,2E<F;#AD?&&H4052-01
@r1826
AAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATT
+
.0.A$+*G?;-D3+A+.2E$F@:H?-H@4&##H0=4(*576,H>5"$&H&@'$/$F.>"#7..C8=!,D6#FE9H8C.D%);$1=E+(9E/"@1B5%H3&?30?9CHE0C*;*!?(:#"&BHC1DHB$E;+?<97$
@r1827
CNGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGNTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGATGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAACGGATATTACTGCNACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCT
+
#%<;>A,F-D00/C;2HC,$$94B1,<*%(5>062(<%D54#B,1$H-=46)@/AG-B-3FC(/'(>F-/.,-E3*1*A!B4%D3'=3>F-;.)1F3'A!;*=3B-0B@$A/3&F+'B*28&-<2/"38A3),*3**>"-9<645':.0+@*;'?E$+-@?+8&1*@@6'BF3H.GDC%GD9439$)$6@?C-C9G@>2>811>43$9:H*$:&*-75H!$$?3+G#?8HA0E;?
@r1828
NGTNCTCGNNNNATCNGCTNGANCTGNTGNGANNCTCATTTNNNNNANNCNNTNNNTACNGCTNTTNNTNNNAGTNNNNGGNGNNCAGAAATNCCAAGCNANANTNCATGANGNNTNNNNACNNNATGCTNGNATAANANTGAANANTNGNNNNCNNNNNNGTATTGTGNNNANGATGACNTGNANTCGNNNANNCNNNCNTNNNTNNNCCNNNCNNNGNANNNNNGTNCTCAGAANATNNAGGCGNNGTGCNNGGGNNANNNCCNTNTNNCNTAANNAACANCNTCAAGNCTGCNNCANNNNCNANACAANGAGGGAATNCGANAAGCNNTNT
+
$##$$#"#!!#!!$$"!$!$!"$"$""#$""""$"#!!!!!!!!"!!#"!!!$!"#$!##$"##$!""#$#!!!#""$$""!$$#"#$$$!"#$"!!$#!"#$$$#$"$#$"!$$#""!$#$!!"""!$!!!"!#$"####$$#"##"$#!$!!"#!$#"#$#""#""##"!$!"""$"""$"!$#""""#!#!!#"#!$"!!"#""!"#$"!"##"""#"!!##$"!"!!$$!$$##"#!$##$!""##$!#"##$!#!""!"$##"#"#$#"#$!"#$#$!!!$"#"#""!$#!!!""!#$#!!!!##$!###"##"$!##!!!###$$$"!
@r1829
CATCCGGATACAGGCCTCGCTNCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTG
+
60.E#)+9?.(G*A@2A8"=9">0<?(,=/:'</=%"7>)FADA-+B)<55?7@G+38(@0-5-C/2F7A513C8@,/&#./3,A#/8-*'6*@1:)%=2CCE#&C>2G&463BG5=?9)&6)G&(7B6-F8*2H%0G)62D&">AB7=/3>G%A=3.G75D8:39:-
@r1830
TCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAAT
+
1<.-/DD1@%E"#2.>/0GH+H##,7!E?@?$5$3H7H?8HF!=68=,8EC6':8H$/F<5D/5#=G4C-
@r1831
NACGNTANANTANGNCAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCAGTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGNCTTTTTTAAAGGACGGTTATCACATTCAAATTTTTTATGATAAACANTTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATCTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAANGCCTATGGCTTCAGTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGNATNTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTC
+
$&"($*(%)$(&!#"+("!&$$*#!)"!%)%*#'!**+"%(#+#'!#$%+##%*+%+!)""'%+#&!#!&)&$+'!&))$!+'''*"$)+'$&#*%&'$$*&+$)'+(+%'")$*%'++&)&($&$!(!**&$+(%)'(&!*('&)&"!'#)"%#&*#&)!%)*+()&######)%*(%+#'$("%!"#'%')"((#%++$'$#(++#*$*#)(%&"(#"*%"($"!)+$$)""*!'#+'(+)'")$+#)&$+&"+!#*&*&(#(*&&*!"!%))"%)%$$*$!$%#+!"*!#$&*+)'')"'')'"(")$*)&+!"%(%*%!$%(*"(&+*&(#$+#"'"*")#)&)&$'+$*+$'*)!+(**!)&#''!)*+)*$(+&*#%!#(!)!&(&$)!#)*)"*&()(&()$"#+')&'#)&#)'%)*++!#$*!!+!$#%#!)!""##!$!&*&*""$"")!'!#%(%$#*$(&"()$+#(+#"!!&%(!*)(&!)%)(&(!("#)!%+#(%!+
@r1832
GTATCAGAACATGCGGGCCAATGCGCTTACTGATNCGGAATTACGCCGTAAGGCCNCAGATGAGCTTGTCCATATGACTGCNAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGACTCTGGCGAAGATCGCATAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATGAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCCGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGN
+
+#&)&)*''!!(''!%+*"%*)+$#*#)"%%+#)%#))(*+!'##""*$#+#(#%*+)&"+'&%+$+$(!!(%$!)%##&+*#$"'###"***$%("(+!%&&)!'&$*(''&%'"*)$""#!("+""$+++("!$"#$%)&*+*(''(($)+'&(#!&"*"!&*$&)"$*&%#!'*%*$+""(*)**#**+"")&#$$)*$*'%#&)!$!&&"))%)$'((*'($++!*!'+$*$&$##%)!"%*")&)##$(+(((%+$))##**"#!*))&)%&'"&)$('*#*%$"&+'!%'!!&++&'!"'('%(%)$'%(')'%%&((&''''!(!&)")#"+#"'$'%(('(*++$)!")%!*#)%%&#%((!)&(+"!)+&(&#!$"'%$(((#!%++&)%!*$#'+&')!&(+"!%*#*!%#$$"!*'('!#&!+$)(%"")$$))&(!&#(#$$#!*$#"#("%"'")"#&)&)+$#&*"$%$'*#+$((%*("($!'+%&%)(*+(#%+*#($+)$!&#$')!&(!)+$#$&#+"!&$%+&##$$"+)+!%#+##*$'$&+(($"(!"#'#)!$!&%(**#
@r1833
TATCTGAAAATAGCCCGGCGTCAGCTCACTCCTCGACGGTGCTGTCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCC
+
0A,8!D/%A9G&6H.C@D&@5%G&C%/C<0EFC<?6D30@1B%HF.2%*;*,7C&B:6.?G-,>?:/<F-A":(-'-!1HH.=06
@r1834
GGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAANTTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTNGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCT
+
7DG*:)&-C=C5@;#>E;#<7-6@66=357.1%-$>"&=-*E+6BF"8E6"9,&?5,<#1:)AAFF<7&F@HF/076#-H=7/'42BC(%21/!8?/**>#=%%((;A5#9F/-!8/07/F2G,H5@3.#+'+/1>!+%*#?E%>25G?/"!A@G8;C<6=.0':5&()A+/"C<A:C>.*F;$<<!C)95'%-$,6))602=?:)AE399%+E)=>6$1.-93??504E7F65F@'+?)+$/00D6:5A)#</F7;B#(@.>)@FB@<F?H/!-(;"A3G?''5.AFE?@CB<07=0<>6,#=+:.);
@r1835
CGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCNACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGTCAAAAAGCACCGGGATAACACGCTCACCATGAA
+
@-=(-.@=?(DA3"1%9>G59!<$H,00.@C"CH;(2.="D1/E%8)#<)C9D@7A%-H<:6-FF!;$"<)';&+FAFE:0#6HB-89H2CB53H$703?'H76$BF9D!*B1,@$:<D:H!!*'?@>5/E3D,D!3G(1(BB$A'(>698<*F<!7.H;G9$=.:/*-;G8E,;"H"+!/H'5+/E$;)BD&:<$(H/8,G.$93>@0
@r1836
NNTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTNTGTTTTATGGAGAAGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAG
+
)!+)"&&+")!""(&*%('+#!#("()'+&+)$!(%("%)*$+#'''$+'$%#*++$(""'#***$)'(*')*+++$(%&)('#'"$$!)*!)&#!+&"*+!!((*$(!$&(*''+)'*)!"+$)(%$!(#(&(+'"%&"!#%%$"+!!$'&*#"+#+&(#++#*)$&*(%"$#&+('$#%#*)!+%'&)'$)%!!&!"+&+%!%#"&(!"+'#+"$((##'))&#%(!+)$++%)'&*%(+%%'&'"($*$&#%)!""+(#$%)'+!++($&!!#!*%$*+*'+"")'(&#"'+#"'!)!)#%("
@r1837
GTTCATCAGNTTNNCACNANGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATCTATGNGAAATGAAGTGGTCTGANGTCGTAGATGGATATCTTTATGTCGAGCNAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGNAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCNACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCNCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAGGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGAT
+
#*%!*)(*)!*&&%*&($'!&%+#&#!'*'$'%'!#*##!'++)#!&($)!(+'#&)"$")$%+&*')$(*()(*!%$&++#+(#'"*#*('&)))!)'&"'&#&#)%!(#(*$$'%&#+*')"*&+#+"#'&('"&#%!($!"!+#(((&%*$!#&("*%*+&%*%&+*)"))'(###!*(#'*%&&#$#)+!!*(')&%))%(#%'"!!$$%%%($"'&*)*(")'%")'#"*!&*$+$%!$+*!'!#'#*'"$&'*#)*!**"#&(()#$"%$*"!)"$!#+(()$&!(!"((''%+)$*+*+$!!*'((%$&*"'$(('&&"&+&'"!%(%!#&%('#*$$++$%"*!!$%#!!%!%*!!""#)$$*&($+++!#$+&#*)))!!&*$$!+$*!%'$!""$&)&))%!$%$&)'!#'!)'*")#&+&&##'%+"!"*&'!#$#+(*%%$'!)*"$*"$*#!*!##+#"&%)"(+%*$)')"+&)((*(#%++#"*+'($$"'!+!*(')'%'!#(%('%#(("+%(())$)&+#$)(*)&$$#'(*"*$'$*&#))%+!(+++%+"'$*'#$#$&$+!!#*$!#)'!++#$$(*%+)
@r1838
GACGGTTATCACATTCAAATTTTTTATGATAAACAATTCCATCCANTTGATTTAATCAATACAACNTTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGNGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGNAATTGATTCAATTAATAATCAAAAATGTATTTCATGGAAAANAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTTAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACNATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGNTCAGCAANACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTT
+
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
@r1839
GGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAAC
+
>,$'B:<6$@3@4BG<G63>A"C93G;6>4(!@""+/F#(?+5++6<C1%-)306'*-.;/--@%+6#HH20-@&*7;#13<'3"@3=FG9;"3>@%H!",2/;H1%,<1D34DD;H7:<;5"0F5EC8701&>(5955-AEB8GD6?G
@r1840
AGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATNCGGCGTGGAGGTGGACAAGGTNGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCNAGT
+
%@E@C/*.@,.:.$1#9F-F>A@B0G24)@9DDF4&D<9*5,B8@,@D;38D;H/9:4*C##6;2?)0#A2E?C=!4%87))5,A<.3G!@G/$%1>92$(A(B3H5H8$/,;/F%)F?<&)"@DF%<)5&<4#<4/F->9$:78.B+4>3C/29H5:&95BD%0)A4G!D1>B#,9>,@*11"'<#(739<0."(76B1
@r1841
NGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCCGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCAT
+
+#(*#"%"!)(#+(!&+()!(++!%!#%&++)&'%($!!#%+*%'%*("#$&&(#+%$#&!&+)"($#'(&"!&)''('"!"%"'('")"'!)*#'+("%&'*!'*#$)!!
@r1842
CGTGATTTCCACACCCAGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGNTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCNGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGNGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCNCCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCNGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCG
+
)/(1$D03G@)?G%7!9'G')!+4$+5$9FF8;24@.??%/.5@?;9G.F"9?E3CD5H=@1!57(C+/@A1497???3>-<65=!C'$.-(E1F'@3C=()@=B(A334>1'<.(?F<CD)H0.G5G7$8G670',;DAE0FG!.<@G.+=!9>-0*285==,,E)*/3>,<)G79=/:&,'83(%62;B:(-3G32$?(6*04:!8H)+>(A)7B#B;62+A7$.;5H;847(,49.-.A4:"G+/$G=-$?B+!%4G2<@:'H43':5F<*F)7GF'"5)64,(=)/??'$(;E7D8"27B>G2)F)A2/!5/5+6:36@7;B!-9AH.<E:E+!*,&'C0'@2B:%.&%'0G0"8!2"74=+1"#4%"GH+,+C:21;.D(9(F--"&G#1C)1%B*&C9G.1;@!A;27!F--0&7.)D#90:!?,.D/1HF<.$<4")7726=CE&4)+455G9+F)(59)&7B)B6E-*7F=860A>&'B-70F6&(!95C2>-%75'E",-D6-/A8':-;!0.>::9/B8:)C:7."9B@&&B4;?0.-66C='CH+8""3",E!3B6DF)%6>C8>2"2@+4<,%#/.>AD+$6/(F+$>.62;2$/G"H%*4@A61EG3!#>?,-G9/5!+&4$8@H(1<,@*;)-:D?E2!&B03!!%5+A,#745;C*;19D83(F,3&0830!0+#B')?1%/./=;)>%DCB*(+-*:5"5FG1+G9HF$*H2-?&="%@90$.21D);54;2=&&&@E,==&:$
@r1843
GGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGC
+
G,54/:69'-&C7%8#C@/7?6#:F!(/9BH&A2-1H5C!)&>?0@?-E41#$&,3F6,;.HD9?=&$2B<GD%9$>-:E=D2G/3.(@!
@r1844
AAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTC
+
F00#(2$A-F#:*.='H>&$<2,4:24-C%/G(:'H?6>)-;@:;948B?87>1-00
@r1845
AGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTATTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGNCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCTAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGC
+
B;$1-$(+-:%B0"*>,'G@2=#;%.0AD'BF'00E+,9./@BCA$G'548#9=809C>B"5-@F39/E!06/8551.;D+G!':9G/=ED(0/9@G@%(D19)=9CE)9;D17&&@?$F4)2&%9<3.;D'8"E,;B/@!)H,?A5/%7E>3@GG=-)%++6%>?-'9B(4D<0.=H.>$'(=B:%$*<G1-17,G-=0;DA+)#ABFC3%6C:9D#,C<G%8G6E-8;'?=B<771#C'74E(D<H84'9/2:G1B%75*<2#AFE/@@<H2$5.;)-5BE*%=A&F4521=B--<#<18C$F=*6&=-A?9'.?$@?.+$E=9H/F11-D+D<.)D<#EG7.-=?5C!;?'6$%C(4$)#721'%7E,"".4"5;!7-(G?%1:AG>?##3,&C)E?&5F2=;%G6+*:.4@)11+0"C5'#8)5
@r1846
CAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCAC
+
&9.DBA:&B4A6,E9&8+'.#:</=#53?34<+0"<5#,#5.A#(=*2:-;3&HG?1*?3.*;.3@<!*+.(F-101!%4A3(A(,1@$%0H>
@r1847
GCGTCGTCTTCACAGCGATGCNAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGNGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGC
+
/6DH1*D+C>'D!<(?$<(#%677:02#(?C/.60F5&<;CD"G"8$/?D1<#9'1499A/5)?@??DH.>=01(>'!E0*<729G644B8",/C<-'AC7)2=,020'"0F;*<+(;GA#-#'&$?:1"'7;F'H@959G2=7?G4<80'E3036-("56:%1%H45A/0@>E1=)E1=?.?.-*&AD@"9F2A.:$98==FE2@=-<>2G5?66%@9E<?(G>D>/+GBFB=%6E=GG=<&108;2='G:%9#6%<:>55-A;D9+,@6-0H8/8<:*655<A7,@.;6@8;?9==C.*?>EB4@'*%.FC+@/G+8&!$1;(A;9F9=@)5134=9"/%D*"C1@-GDB,8F.5A#"'9-7:A'1'E0;2#/$9:;@#'*<'79CC=&'>:85,"<BH?FA;(35+5=',5!&C*1A*B0%,;'E1<2FGG5H:'"*D<3;1>C))"0<;?,-@%A(H,4;98GBD7611%24H,"H"?&H99FA93"&
@r1848
ATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGT
+
H1<6.!8)';";0G=#9;,=8A=C$:HF?*;;C/EAB9+0;B:3F76.;86+",1C.?A+D#02<:4&0?BA.,2D;)5,5
@r1849
AACATCCGCTTTCCTAANCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGNTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGANAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTNAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACNGCGTGTTGGCTCTGTCACAGACTNAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTNTTTACACGAATNAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAANTGAAAACATTCCTAATNTTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCA
+
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
@r1850
GCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGAT
+
7+>%G73;!31($)#A),E*$C140+%C)H3(AC0E/%D2"C12>>=A45C%:6
@r1851
CGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTGGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTNATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAANGTTAGCGTTGAAGAATTTAGCCNTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTNACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCNATGACCGCACCAACAGGCTCCAACTTTCCTGACGGAATGTTAATTCTTGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCNGACTTGGGGGTGANGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTNTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAANATCGATGGAAAAACNTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCNGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCANTAGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTNAGCAGTG
+
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
@r1852
TAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAAAGCTTTCACCTAAGGAAAAAAACATTNCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCG
+
H7022$H(E&60A@)1-%#=-F/#2C"=@D8)"G%3A4C:+?)"G(,?'8/0)G./9:!55@414?(H!%%:(>1A;&/?D;:>G@(,4>63097-)&#CHD&-B'F59-D4:)6>95?44,(G.,4%)D!3!#<;8$"H8C'&4).+%.E*5>%>A:(.<@$81%>0:8@=.H.0F57)&8>+:G#@0=5*1"9@(B>!<G;)DB2#()%."%9!1H%,:9.C5:FF%3H7.HDDG5&=>H*8
@r1853
CAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTT
+
HC:<:?;9@&#&.3.;B29=)*"3E@47!;7E--0!F73?@&.B,('6!E9-2>+<+-??1$5,)332C/E!.!2%%F7D(:4%7HH-F1%7/>B;F+0.G.0F6*1:0,)'-40E-#,&5.HC<DE21C(/+*HE-&)?<CFB@7-++*+/=$9C?-H!168%H4&G++E46(47$%-9;'%5!D<%9/.8)>?,AC5G=F79/.8,-7.%@GG;?@5?+"EH;("H"H9$7!H4H2E."H%A0.28-G<G#**A3&=$%(>8*D,A'@/4%#H/".C%9.*/$B9@"9
@r1854
NTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGNCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAACGGAA
+
!G-514:H#.BD=F*C7;B$$G'8,/,?*>&7($(GF285+AF312C)07/,?485''C&?>G45.(3)5?$44E*3?0!4)',0@-FF;9CH'.B**3H?DA:!+E'&3<<+4!HE2)HA4&9&*2/C,#='4);,4(F/+F2-%)3"%/-H:8:%D)B90">5$0*A.01':1057C"'6"##/?*C/;F4/*$>$/)9E8-:+$#,'%*A"1-/%9A>571;>@+7&('#%*8'5A<"G-%>3.9$,6=)<;82B8C1.9.D<#&+=1<"?6.+F:A08$E3/))@F*!H8>:%@A(;1((/F9"<<:A&GA.8-)4'>&?C/B1%3D$%42<'2>C<E#FAG!G29B;G#F%63(*$%G;%(38$38(@D*G"%E@*%384?$.=8H;&?+D;(1$$6B7B78H%1B0
@r1855
GCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCAGCGGGCCGTTTTCACGGTCATACCGGNGGTTTCNGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTNGCGTTCTCGNCCTCCGNCGCTGGCACCACGTCAGTAACGTCAGCCCGCGAAGCAGTGGCTGAAAC
+
5!+:6HG,<G=0=(6(>96:G&24/B+E9F;';E=@3?F/#B,1,;!>:0E@5C!9,C:!&/(GC:20=C199B!F=4-=.@9G@;8<+@E!0E:E7><83;%F?"D5:!=@?HE%FE&?@6/9A"*":>A6A7!"4GF(":<:+#+4'C>AE1&A!'716(=77,:":.EA1GDHC?G%/,:5/&0H.!054/C0"BC&*$C-G<**=-/0>E<('D=<3#/@+G6A0=*,.BA?=/!%&#6::;B%D9DE.<6GC239%#4""C43/:%:"2@<#@A-6-C/%94/8HG>B*G9$(@
@r1856
GAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTNCACGTACAGCTCTGAACCAGGGGAATGTGATTAATNCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGANAAGCAGATCTTTTTTGTTGNCGAATCCAATCNTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGNGCAGATCGCCAACTACCCAAAT
+
D!;3"E768#5/$55$$0#"+37$4>E<G4A:+23C*DF7,(>6,-4'7D!()%$E;--&$94?$>7;##1>7,$+-)$AE&*.1203">99,*4=1,@&+=0!!/#0)6>2B7;@(;7*<4!E&<9/+1,"&'%*#F#G0D29%9$71-AHB&*G+4"70G>@2-%6E>:CFF94G13=31?*F4G+00E834:22:0@!?(&D-C=(%0>#<:,EE?2==%3/4"'8B>8!B'(:"<=H6(449=%<F>C?55<,"-,=
@r1857
TCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCTAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCATTTTCCACGTACTNTCCGGAATACACGACGATGGCCACATC
+
B=,4HG)4;F:<#-787=)C+$@#67F)%B+$"F?!17-=;A56H.)!@@B=B<;;*&+/C;"%#(*;"%62.;2HD'DD+C053,/B'9%4<<A<B!,(5A49AD0/'=$!A((EA7*C&=BH.4A=::%3+<A;+3;A-8&6E84*FG+EB8>C)+#++>7823+?@!6AHD411+'(HA7'5H0(6?%-G(*-&',,6'D."6/B#5#?8)H2':)=G#+**"B48,$<7.2)H=+=6)<F7EH792@2<<H!79:$@9'0F+?!?;CD',/7$F9$/B94(5A"E5E)$@(4:-'%??63)D3#*4C@#B/"4B*?)EC4$27+55,3'
@r1858
TAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACNGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCANACAAAGCTTTGCACTGGA
+
;,BC)@2':9#:@8C9@3/D-A49)-@>@/1#"5-16#91',9,C*@6",50D#"B2BH>$0?:B'043!)*7@3<'/%83ED'-?"#D7>:';C/1)*%3@9EFC?;7/<C1!)&HFH+,6;-$4:>6>G"4.;(?5<135:D&-84C8?9E2$!G&.2C9.>8)2/;D2!)F&=A26)5=45E+6-$C;3:.%/++3?*$2.-@A5&"+/=*"
@r1859
GTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTNTTCCTGAGACAATACAGCACGACCGCTGGCGG
+
:-F>89#!+#/$2#/",+*7($-.-D8>9(49:#AHHA*FB:F&+&:"B?8.5"%3(,8/'/#-%58G6%1,!85>2@C
@r1860
GGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGANATCAAATAANGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACANACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTNATTTTTGTCTTCTTGCGCTAATTTTTTGTCTTCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATNCAGTGCAAAGCTTTGTGTGCCACACACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGNCGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTG
+
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
@r1861
NATNAGGANGGGTCTGCCTGATGCTCCACTTGNAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCANCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGNTCTGATTTCGTAGATGGATATCTTTATGTCGAGCAAAGNAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCTCGCACGAAAAGCATTAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGNGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACNATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAANAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATNAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTNTTCTTGCGCTAAT
+
#%*&(+("##')#+*'(%!'"*!%$(*&(&&*"#"!%*""")(**'"%+'(""$+$('%#&*")(+$"#$&))$$%(*')#"#'+"%)%&$**)'!'#+)&#!!*++#('(#+*"*%%#'!"#'*!*!''*&!%#*$&$$)$%$*'!)$)"%()"!($#'%$$#%*#!%&$'!"$&'*#+)+("(#'**!)#'"+!'#*)%(!&($"(")+(+*$+)+"$"!%#!$(%)'&$%)(%)*#&'#"("!%'%&!+((*)*"&&)*#%()%"!(%!+)*)"!*'+&*+*'(')'(%)#+&&%!*%'$&$)%+'*"%#('"+#*"""#%$##++&!'!'+&!%)%'#"!*''+#&%+!%("*(&+()'(#&!%$$!"#'++"&!*&&*')!"**$!#$++)'#)+"$#&#*%!(('+&'*)%)"%&(!$)#$''*(+'"#*%!)*#)+'((##'%$#+$&&)$!*"#$!#))*$%()*##")!)&(%%)))(&'!&"*&&**%"(#*'!**#$*(+(##%#!)&)$")!()#+"'+#!(!)"$%!*(#"#))$#)!)($')'"%+(')"'%(#%'())'('$"&''%%%&&%')'')!)*%&!+$(&#)*(%$&)###*+('#')#$""*$(($**&!"%((*!&)#$($%)*!"*"&"%!$#+&+((+)%)#")'##"#'!(&##%!!#!(&!(!((&*)(*%"%+(##*&*+))%'#*%#(#$)#$&(&(!+*(#*#(*")$)#+$++)"%(&$'('***!&%)&'&**$!((#$)&#!"!#+#('#!"+%&%!$)++($"!&&'+'*+(!)&$!+#)&$()!%***#$!(')%%))#$("#(+$*$&%()*")"&'&"$)$$+&(%+$&%!)($!&'##"$)+$(!%%!()+&&*&%!&(("+#!&+(%$$)*&'(%!%%+$!!(+*)!%)(#&&$(#*")$&!*&'!)(*+$$('+('!%(#**+#"$*)'(&"'!*!$!$*+*(%"#!+$&&)"#**!+$)!%+#&"*%
@r1862
AACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACNGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAA
+
GE6&5**$+<6;G6G05HF)G+0B=7)@8HA<+?H1?GGF)?D821"+5,?=5/:(-.$>$/64B.F@<$1+G4(*<;:073>A>=4&H)!F)=;A1(+E"BD50+C8%.+=8(&-.64!87*AB/0+":
@r1863
CGNCGCGGTGTGCCTGCCCCCGGCTGNTACAGCCAAAGGCATCCATCTTCGAAACAGTACGACNGTAACGGGCAATGGCCTGCGTATCTACAACAAGCTCTGTCGCCGTCACCCAGCCGTTGTTCGGGTGAATCCAGTTCACNTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGNCTGCCCGCTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTG
+
$$#+&#%'"$!$'%%*"%$)%))(#"'((*#!'&#$!!!!+#)*))*!)#%&%()*"#!#%*(+!%%!+&%)!+')%&*+!%$"(++)")$#"$*$!'!$(""#&+)+(+)))"$+'%!+$)(!*"!)%"$&&$"*$)#*+#'%!*$+'&!(()!+#%##""*$!&)*%(*&*#"%'$"+&()!#)(((()"+&(*&*)"$!$'(&$%&"&&)*'()+&(("'$"#"&!($)')%%)!!*$)%#%'%#*&%+&++)*#$))%+""'$'!%#"*%)''+'$$&(!"+%$%"#)$"!%(!*&%%"$'#)!#++*#!&**##('*$()"(&)&$)"#"$))")$%'#(&$#)""
@r1864
AATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGNGNGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTNAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGTGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTNAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAANTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTNTTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGATAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCACAAAACTACCGTGAAAAGTCGGTGNATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGNACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCANCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCAATGC
+
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
@r1865
GTGNNANCTNNGGTNTTTTAACTCGTGNGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTNAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTAGAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATNGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTAGGAAAATAATCTCCGAGATAAAAGCAAACCCGCTAGAACATNTTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAANTATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTNGTGAGCAATGGGTATATGCNAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGNC
+
#'"!#'%"&'#*')+(+'&+*&!$*()+*"*%$()!'!'($")(!##"*+$$!!%!'$*#$&(%+$%)(+$*"&)&(%$'!!'*+)"%$#&*&%$$)*%#$&$%*+&$()$"(!"&*("(+'(&!(%"&*)#(&#"++"!#*!'!!'(#+*!*##&%(++#'&+%&&*"&$)&)*!'&**+!)#(%!$&+!&(#"&()%#("+))"#+%!))#$#&%'&!$"#)!+(*'&$%)'&'$!$%)'"#!*$()'"%$&*!+!%*%$'&#($%&+$!*("$#+!%&"*!++#+++)((%)&$!')*))$**%+)"!!'!#')%('&"$#%+*)#'!*''(*"&'!&**'!+!+(%!!'!%!'"+#)+'+!##%'(%'(#'*"+"))+#'"$&&*'#)+"$#)!)!++((!(#$(&#!$#%$**%%%(!"&&'"!$!#!+)%%$")&(#%&$!&&%##)$*#%"#($$+#!+&!)'$$)$&#+*"&!($$%#&'"!''++#"$!(*%&&"*!*$''+"+#(!$+%'&+(('&%*#"$+"%'#(&+&%"'+&!#)"%!&'##+'+"%(('$++(*)"*#&&+&$#$&*++&'"("(%'##)#+%&(($**&%%(**!)!#&''+*+'%%("&'%!*&!!#&'(!$%#(!%%+!!##&*&++%$&&"()"(#$%$$)$''%)'&!%)*$*'!#&'**"!*+*'*$!!''+%"#'%%!$&(&&+!&#+*#"%!&(##(#*&)&$'+()!%)#)*"!$!$&*"+%!+&++!%#)'%)%)%'"&$+!(!")#**#&'#*!#!"("(
@r1866
CGTTATCNGGGTTGGACTTCTGCTTTTAAGCCCTGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAATTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAAACTGTGNCGCCGACTGCGATATCGCGGATGAAGCAACGNGGTTAATGGCCATTGCGNCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTCAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCNGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGCTATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAG
+
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
@r1867
NTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACANAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGNGGC
+
#C>>822(%)G!<,#4!H.>8)DC@H>$@-D*.#%($DE)1-;E,1:+;!A#/4-4,6C';5;1A&E:H-#E=.&$)?@/#D9*0=(#%3(.F67:@98.G@"7&'-9;!*8%F:$$+H:05D9..C,5C0D#E6"B7@<@F8+-80A%GCAF9+46<%(-!93D)$>H36HG3F2/EE9?*:":18@CFF#5=+-28E2C<+DE1'&@(7D
@r1868
TAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGAC
+
=G;!.0?=550(/8.%6H#=A:E,(*5HD=/2:D1)%;7F01+&B#<H#)9=?$?*F=@%>@,C&HA3D%76;$200-G26B:+5(=$@!1"+A/C,0?966>@&2:#;!,!7>C<,."*%*#C52452''27'(%432$E!?;C("D0#+'GB2.?@:5&;421+:-.#%!,;$+'C)/E"H?@'+4'4.0%-H@.E6#4=@45<&BFE02FE!/-6FH)(8A&FD63?87&=#9G?0>%4G.4!HF(9%?$:1"&A&@-H-6/(%$3AA8-15!GC/(<(:55*E.-E15:(@1F6.(-&E3
@r1869
AAACCCCCCNNGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTNGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACNGCAGATGGTTATCTG
+
;F):@,8'%B,D>#161:./!)F,1)A,#G<.039!/9?)&6D:83"G#)GCA@51)(!C4@.7>/G?AC=/!8(F#"719?*%>4G*>)*7H7:&BC076@@F#C-DD&A9)5B3')?"/#";E11B;,*9C&.&83E#DC6:B7D8,':@--B#1-B$<F3A7D<<>F$3"4*&.!+&3(&#@@&#'48>.%84"//6'<8=,$011AAHE"521+</&!&"?-3=$+@:*;/<+"%;
@r1870
ACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTNCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCANCTCTATCTGCACTGCTCATTAATATACTTCTG
+
*76"7(:3<:"EB5=9<?E9(1<81??*G-?"+F=02*$).+73&9%%52-E5D6?)37/<?#$H0AF-&=/@<5??+'@7;(EG)("DA*6C,*>AD.@G<"(3,1G>37$
@r1871
CATCTGAATCAAATATTCCTGATGNATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCAT
+
B35B=@6291C'-B()!.C7'3,C*26E!1964EE>G/2)?E6>FC>3'%D!79%E)$2?DGH.=B>G578E36DH0>BGG?
@r1872
CCGNGGGATCATCATCAGATTGTTCTTTATTCATTTGGTCGCTCCATGCGCTTGCTCTTCATNTAGCGGTTAAAATATTACNTCAAATCTGTCTGTATGAAGATTTGAGCNCGTTGGCCTTACATACACCTGTCGGNTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTNAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAANACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGNTTTTACCAATGGCTCAGGTTGNCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAG
+
$!*!$+()!()$((%*%&('(**#+!"!$(%'!#%*&$$&!*$)%$++++)$(*)$&('&$"!)#+*&'%&"+)*%*&*+#(("##)#(++&*!)($$+'%'"*&+!'+##)%++))&!+$%+&*))&)"+$+(&!+$%)$%("%#%'#*!!*#)+%$(('')"%'&%%+'&#'"##")"*'+()#(($"%)$'""(%$&%*$+$"'(#'(!&!)#)&"+#&%"'&)#&)(%'$'&!)#%*+)++'$%$)!"""!%&%$)$+(%+"#'&$++)*$&(&!)!**+##"$*++#*'(#(&!!!&'!!'!+"&#%(!*%""+&#$%'!&"!)(#$*""(*&!)*&#)'*#++$#&&"!()("!'&"""!")
@r1873
TTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGATCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGC
+
A1F!&46&$$>20!B978&,0D@4/;-<HF"+H?H6@(:92-78>$5<@FC95</GG4D0.-%$(#14A=>1D.%%%>CA"1B517;FG*A8<C((,>+/$="3<<(41B9<,&7E=+G/&2G1=3>B38'5(E-:9%E5)"2G/%1E%::5#EF$/<*#'94H$/827+.?5!0.16(&D?/65(18(0.
@r1874
CACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAA
+
C<6*:1:1;)7%.C'>E45+0>?:F2ACCF@),4F-,93A*0?1AD1G/*60";765:$0@%)&=:6BG(=E-BC(%AH?C."(@$HFD21
@r1875
GATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCNCAGGAATCTGTCGCAGANAAGATGGGGATCGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAANAATTCTCAAAGTTAGCGTTG
+
87A?;"9(.E(07#*;/*5F#;:G<>8&/-*$6!:*4(B,>19*>;B5*&?++-$&(D'"=@BE+4;?165A!*,@?1&1'-(,A;/B*+524;DC'H>G<0$#1D"*/65?.F*!H1B3@5G2.%7=9B9(D288;<(*?-"$-#BBC8.)=7$<*&AB<A>GF5<,$80+"/$0.$D0!$$,#+"))F&.1E<)65D83';;:!6G5339C"&29:E?3CG&!*62A>*B#8"BF0(&3=3:=.4G8&/#7':&
@r1876
TTTTCTATTAAATGAAAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTNATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATNATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCNTTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGNGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTATGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAA
+
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
@r1877
AAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTGGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAAT
+
&)'$%59,&@4-A?>A")750HEB2E8D8-&9*:9"!@5FE33:H$4"9"$!"/G8,B+!!5&H:9C<G<?"&&(F,/)4+H%!EA45C"$"H2@5';?&A.>%?6)+G'6-&76=G;%*@!'8;!/0./&#=H06-H&30)C??'&;>B7"/(@
@r1878
TCCTAATCAGCCCNGCATTACGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGC
+
#>;"'!B!(-8&0@&=@'$?%&;*H7)(F5.=8;H;?;%$!F&H*@;H,B1&+.'!/;6B/>%&G52;H,D9)D-9.5F%1HC)68C;'6G@5A>>DBG-"EEHC:
@r1879
ATAACGGTACTTCACGTTNATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAANATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGAGGCAAAGACAGCAACGGCAATACACACATTACGAATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATGTGCCGAATGCCGTGTGGANGTAAGCGTGAACGTCAGGCTTACGTTTACCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTANCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTAATCNGTACTTTCAGANAACACATCGAATACGNTGTCCTGCCGCTGACAGNACGCTTACTTCCGCNAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCNCGCCGCCTTTACAATGTCCCCGACGATTTTTTCNGCCNTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTGAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGNTGCCCTGCGCCACAAACATCGGCGTTTCATTCCNGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCA
+
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
@r1880
GGCGCGGCGGATGTGGNTAAATGGGNGCTGTATGTCATCGGCCAGTACTGCGACNAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCNGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGANAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGNACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTNCGGTCGGAATGTTANGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAAAACTGCTGGAAACGCAGACCGTGGNTTTCAGCGTCGGCNCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGC
+
**!+!%%($!"*'&'&$%$&+"%"'!('!)$%&#'"))(&!$))#%+'+)#*(%"'*'(+!'!&%'#!(!"!(&)*'!!&+%$")$&&)&%!')$"$$"((%)*+!#&)#$!#+&&!)**$*+'(*)#!&(&%!(!)%)%%#!"+""'$'#+"#)!+#*+)'$*"*++&!'+'#&(%$&*)$*+)!$%#(*(&)"#$"+)'&*((+$)&$%""()$!*)(##"&(""%$*"')%*$$*)*)'**#%(##!#&!"''"#*#!$$$+#&"%)!*!)!+(&$'("(##$+$&&!+)$&&&&!'%$#*($$*+$($+((*+#%)(!')!#*#'*%)#&#%!!&"#"%+#**)(''*'((#&"'*%)%*+(*)**)(!'!#!"*#!!!(&*((%)!('%""%)(+#%#$$&)%+"!"$(!*''*(#+#&)(%)"%*"$"!($!%#%+#*$+$)#%(")))(#&*"'!(&)"*"&)$%+&%#+'"'"#&"()+"$)+$&*%++'""%&)$()#%!%"!#$%&('+!&"$"'&)"*($')$*)$*+")'%#$#$!+*!)++%'$)'%#!&*%#*'***)$'!))+(&'+!('$"")))'%+(+"$#+*''*&&()#"%&*%+("&%"(%$(+*(
@r1881
TGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTG
+
7<;##(G&%'0H-C'>*9G9>#"G8;4,#%A*F;,E.%>CF-C>'>C=;>#%D%(,"
@r1882
GTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGG
+
?HDC?,8@E!@"8GB>C7C=CH'$'',42"F;7)#;#C,1%F((:%/#<H=1,
@r1883
GCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGANGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGACGAAACGATACGCGGGTACATG
+
4%@DH)%>75*'7D9<F!7G!"B*,BBB8F53*=<<5++9"$A58/E1HC@9%H3B4:>1#7F/'6#12!BH%"!-4F/6'7&CE+$19;+6=894?";D9>!!;8>%H3'<1+.&*2:08&.<$(F97'++4=6,8*.53C5F8F:1;,(/(=:3AC'&/<E&<<A67FD6$182G(A6BDG(4:%!?7&$B&$H
@r1884
GACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCNTCATTTTTCAGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCNG
+
G*+$<8+AE9.A>@39G<5-3E5/F969(45A(826F+&0B76:":?H6,>#H)#2(@$04=,3D>,.&G69;.6G#6@"/:/E<9358G0!0<@<1@,+27AFD,)"-2,7:F63A/E$)2G9(15&?(;B6:1*/,95-!!+1:8>:F>"#.+&@&GB>&B*=6H<BGC$6$0(4"!09B)C1#=>-0B)?*<-!9+F'F"!/"B!%2&,=(3&%;7"<4FD?<!3&:H3C'2DF
@r1885
CCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACAT
+
D%8E$(=2#,8"<*C%C<,=?6"/21)+-B38'/H*()"@./?)65@A++;,9G*+C
@r1886
GATTACNCNTCCAGTCNTCTNACGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTNGCCGAGATGGGATTCGGTTATCTTNCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCNCCACGAATGCCGANTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATANTTGCGGCTANCCAGTACAGCGCCGNACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACC
+
)'!#'(")"()**''%'%*%$!"+*(%+&%'&%+$(#"##!*')"+'%'(!!'&"#$#%"!*)%(#*"$&%$'*$'$+&)$")+!&%+#!+$&#!*!+'&&+))$*$'**("&$!!!!(!("&$%#!%'!'$%#+#*))!#))#$$%&%)&!%"(&(*(%(&**(#*$(+(""$)&&*#)+#*&'')"$#%)#%##&)''$*%&!##(%&##*%+)())&)%(#%+(%#!(*"++%$'*'"*+$!""%+%*%*#!#%!*+%)%#$")&)"$'$(&'+)*!)!#!"#+#)"%%+!!**#&(+(!&++#
@r1887
TGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCANATTGAGCGTGGAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGANGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCAT
+
A"*)/41F.B6F@'/$><:<*<-D,,4/;=%/62)"0+A(,3BG6#:*=0F"=03-;DA55!E+D)2;+5B/0'GH8/F3+:9&)$A1.5)!,4,2&<D@!3&)9HF::7286!7)/776C;4ED<#22$)+-H/B-9A$B0':@3)%>D',%87*D9)G?8C>&+FHE)G>DE7%717E!B*-A8:A1&31#E"AE<919<;',8C:;E703'<0&,E1*F=<7B?0&F?CAD2=!G,1(5676D85/$,F6%D+-#=021;-21G,@1";.0!4D81+91?H5(?7>G*<'=%=A73AG9:*/@9C-8H"4.E-!#$.9A
@r1888
CAACCCGCCAGATGTTCGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCNGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGANACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAAACCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCNGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCGCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGNCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCCCTTCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACNGACNATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACA
+
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
@r1889
TCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGA
+
2.F;9F2*/,<GBB4?>5!3$8;D4A1@-5#(03#F9$%*@B/C,.2/178?B2%8E('<7=%,BCE*61?0D=E*/;
@r1890
ACCGTAAACGTACCATGTCCACCTTCCGNACGGGCCGGAGTGACTGTCACCGCAAGTGCCGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCG
+
<2?**;%;7/863*:/D,;,E4$!-;9")C1#+<0C2,58-5).</?EC<%0%$-2>#(@%.,G>6CA0+,#"=2%A5&09*9=B&1%=?,6F?@@4(6=:%**".?(/B.,/?#9$'?5/5->&C-$'1@EDC/"
@r1891
CTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTAAGGCCACTGACTAGCGACAACTTTCCCCACAACGGAACAACNCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTNACCGCTATCCCTGATCAGTTTCTTGAAGGT
+
'@*256./$+7-."2F##*H>D;$-/>7-%:=5A-D9@!(!"7>3."<0<D/--$A3,2-0.4A,C85.DD@E';%9,72BA,H:96B@HA>(=;)6*+8$7H-5&:2;A/;<,1A=$'@>5963B8G!#:";-&@7&%5*."/<7125=+;*>A.-7+%85?6A41(E1'GC>4#0.EF26A.!);;&9=(E@HC=$D@"5+GE%#7(1#.F>1-9?1&F!">A/'%E)BH=<86-13;8D""C
@r1892
GCCGTTCCGCTACAGCTTCAGCGNCCTGAAGGACCGCCATAATGCCGTAGAGGTGAACTGGATTGACCCGAACAACGGCTNGGAGACGGCGA
+
EC7CC-*%?<3".9-GF"CE&AB)'7/B4G%*0:4F*+3@0#?$B>2/'1&H(;C$>0-4D-:=%7C29F+&(%?9#13=0)13/2><"@%F
@r1893
AAAACCCTGAACGACCAGGCGTCTTCGTTCATCTGTCGGATCGCCACACTCACAACAATGAGTGGCANATATAGCCTGGTGGTTCAGGCGGCGCATNTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGANCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGC
+
#'*+))%!&)%($!#+)$#)&$+"$"(!$$&)+)+&*++*'+"%(**'&+''$%*()'#$$+()##$!$")#$#&+%'%+$&'+%)''**++)&$!!(!*"'&#(&*!)$(#"&$"+(+'%"$#%!$%'(")(+")&)*+""&**'#*+$&++&!$'!(($&)"%"#""%'"(#&#"!'")("((#*#*%+$(&(#+)
@r1894
CTANNCTNGGGGGTCGTTGACGACGACATGGCTCGATTGGAGCGACA
+
)(#%"#%%+$"!)"+$!+$$(%*!')&)*+*&$+$')+%($&*(!!'
@r1895
CGCCGGGCGCGGTNGCGGTATGAGCCGGGTCACTGNTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATANACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCGGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGT
+
':H4/,((=4CG(C<2'*$<*C*D/!92DG=4+09=*B1=#;*$=666@:G,=.6A0$0F!(1-G@-#+DB,GE=;<H5.9?47*&&=?8(EC572)%)F2-#C7%"(6");#GA"7<)6;$9<?@-(41.@<?A2'10;.1H)B"+G6,-/>3@@33/A%8-B-(.0B>")E:))0D+2+A-$/..D(>C$'-:*8.D%?8%
@r1896
CTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTACTTAATCTGCTGCAATGCCNCAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGCTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTNATCAGTANATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAACATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATACGCGAGATNGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCAGCCGCGAAGGTACGCCATTGCAAACGCNANGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAANGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTNTNACGAAGGTCAGGTGTAAAAGGGCGCAGCGTAACTATTACTAATGAATTCAGGACANACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTNCTGCTTCCGGTATTCGNTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTANCTGNTGTGCAGATATAAAC
+
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
@r1897
GNGCAAGTATCGTTTCCACCGNACTCGTGATAATAATTTTGCACGGTATCANTCATTTCTCGCTCATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACC
+
*&+$+!$+#"&'!)#%*+'&'$*!%*!*%'&#)&%'+"('+%'('%*+%$)*"'%$$%(!%")%+'$#($(+'!*$%$!+$#+&'"!+)*((*+*%*!*+&!%!(+&)#%##"**'%!*&+*#$++&#+)!)'#*!&%+!$#)%)!"'"'!%"#('&!$$+
@r1898
AATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTNGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTNTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATG
+
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
@r1899
ACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGTTGCTGCAGNGCATAGCCCAGCTCTTTCGGNAGACGTTCACGCCNTATCCGCTCAATATTTTGTTTAAACGCCGNGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACANGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCTTGCGGCGCGNAAGGNCAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTANATATCACAACGTGCGTGNAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTNCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGNACAGAACCCGCAGAACAACAACCNGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGANGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAA
+
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
@r1900
TTNCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACNGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTC
+
F88!F2/*899-+"(.72@1-@,!-!?=</:A1&6>$@:+5<A"?8+D9*/>)&2((<+9$E!C?!F#BG=*1GFEF.H'.!E252@5&+C).+/?%H@E%'?";B,$G'#('F?#3;.2=02.'1),A+</E1!3;:*4&E%$4G$CE7/AC#1#D*3/)GG313H:E&?H0%G59F-$H$.H!
@r1901
GATGNGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAG
+
A7$1H%A#0;=6:800...8$E"F,#6<0.=,$"5,F+/B3=:$'B8,,/-8<E"8;G7(4H$$;(;.F.0'9E86D,).7:>3A77&?+,4D)";187#C;:5&(=6#>:5>22+"(!-5B--4)E"7G?H0".*/+.?E:6@B6+.C4&84FHHE@*B@G.'95
@r1902
GATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTNCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTNATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGA
+
90@;%G<G1+6DA.G8F)0:A$D+')G%/.5G+8;E?&3>6*D4/@C+/1!"5!1$B?-+(.0)D"1B(D1&%;5>>4/EDB'A(6@$)EEB#&:AE7!4GB-;3=8#8%:91E2#4(8;=219#1=(.$9,3+>,D#*--*25=6*)(=?3?D1;/E,8;2F2:0">";H6)?A*<>>2)+:8:<%=A51<5+G(,9&)&";>?GE*G(FB/4@)2+C>4)!+#G,)5:=;%3@F=G"4G9
@r1903
TTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTAGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGATCTGGCTGAGTTCGTGNTTACCGCAGAATGNAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAG
+
<A=2<"!)/="+482<C9B%7%,3*&.,@@/-;G9*#::E=,D#D>-=48!0-45GB02C;<H76F"'1=C#-D49&'?!;-*GD.*B>-!4=-FA9;@F@3*4D,B)6)49HE+$70F1.H6&A+0*E4=%"1<E19G:!'?+)*C@&$H$E0;D*C'$%-*/23;&C9'85.@6'.:<32B0G-35745@!%1'1'<!(D4E"%G57=**>15)"9-!@H!/23305E8-3B(,418F8:/FH43%"2G".?+%@28A1-*,*:/?("59)6:)"70=$9!'G'35+?
@r1904
GTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTNGTCGANTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAANCGACGATGTGGNTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCC
+
-."@-'A)0<696#FA>8D?'18(G+090@G&?+3<7DHB,;#=9$<7,>>83D14/?G8.5CC@7(29AF61BF6B$3)=*7,5=99E:%C1.0/63<&DC1>,72FG:0):D,3$)!(10-*4G'FAE"=E(/1<9<=?1-4?FD8FC?#<.D9==*H%C)<"0E8*=''"#4>D$6C$.8)?B.F&2,@%.-<<5,9.'#C<;:4&7H/.$%;",(%%DB>*+$&D,)$7C/0@A',FE41=B#693.0(.<78D5=&%2>0<F'3)#+"E!*H<-A?>@$!>+C%B5B4,/@+FG2=!B3A,D94!,795,<7E*4!G"*'E&2%0A*.>HG&5G!6(F=C.$$09%2.?#&'$?B)4E7:A>H=)$:
@r1905
GTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGNTGCCAATCCACGTGGTGGAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGNTGAAGGGAACGAGTTTTAATCTGTCAGTGNAGAACGCGCCGCCGACCTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTAATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGNCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCNATTACCAGCCGGCCTGTTATTAGCTCAGTAATGAAGATGGTCATCTTTTAACTCCATAT
+
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
@r1906
AGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCNTANCCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTCCCGANGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTG
+
>7%"7;H,%&E5)G-%0E3'D3;)84D0F5!"!84(2<4!D1%745&F:B?E,4.<5&7@)C<37G?.H@*2-H6>'.-EEF@'1/H-!64F.84-&02&;@&&*0A@#.7&.$.-H*".0@)D#$:E,1D(773$0#*+2D<<H.7C..=6>6613&)FE76F(8;)C-D.
@r1907
ANNATAAGGGTGTTGCGCTGCTTATGCTCTATAAANTAGGCATAGACACCCAGCAGCATTTTGGTATAACCGACACGGGCAGACTTCACCACATTAACCTCACAGATGTAGTNGCTGCCCATCGCA
+
"!#+*#+""!&#((!"+''%")#"'#$')!#"(&++""((+"%#$"'!%%%%'#+)'+*+++##++%"%)&"!(&)%&&!&(+!*+$!$$')"%")"(+#%)$'*(&(*'&%!+$$#%+%#*%%&$
@r1908
CGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCTCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTNTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATAC
+
.A';4?3,>6$C9(2C2C.9(-1GAG/8$:-/?'FE,F&1@A.1?5D:0H#G6B*")!=CF7=)%/34G;%&3&/42>B$3(99?*"/CD7<;@=HFG;'A,**E=,CE+G@(1C?A2$$9.>89@4C$9?-B8>D?:G9%19E>44+6?;&1'/!+465H/%A?:5=3F1(':?-28?8.9.*G2=@+#8<+A9D3#!6&+,+'FB=9AA%FA4">-F9B*+H(@*/+B)0,<!/514%>3/!D<C87&.B%C,":<ED;9$*$A"-G;0'&)E0$?$G>3'C3>:%9405G+'H8#C3<8?:B-9G'0
@r1909
CCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATNAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCA
+
7C30(=6F6.$15H:42!)A2E(=E9D9GH#4'473<"!(B7;G9<CF*76?!5$D5#E3F?1HCG)6159$C:-0E$?B)7!?-)-7@"0.G.D89+"E1)@")6?-E3E7B.%#)&8C@"4+-+AG2<69=F=5+.7B12H2(H>+9429*<':B%?<BA(3E3"2/
@r1910
NGATCNNTCAGCGNCGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCNCAACCAACAGGGGATTTG
+
!!(#*&$!&*("%!#+#)"(##!*%'"()))+)(()$)%'!+%$&**)+#(%)*')&)'$%"+'&+)+%**'(+**)!('!$(*"*(%#+++!+&$&+#%#"%%+#%#*&!&&)+*')!'#&#&!%%
@r1911
NCNCNGCGAGCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCTAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGNATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAATCAGAGAGCAAAGGTGGATGCAGATGAACNTCTGGTTCATCGAATAAAACTAATGACATTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTC
+
)#!!&!")'+(&#"*"$#"#!+&#&'&)+)&#(!#("'%''%+&&(+"$((%)"+#$$"+'#%)!'+'+$%&'&%)'&&'**(&!#$%#*""#%!'%'#+'!""$%!+')%(%"$+(++%(#''!**#)##+!$!%")#%"$)$)''*'#'%'(!+$##+$"+)$(&"+$%")#)%#%"'+%*))"'%+%'+*'!!+##'""!')!$(&%(&#&"")!(#$'(&"$&)#+"**&#*$#')"$%+$'!'"*'(&)'#)'(!+&+'"+$!"(&'$#"%&!)!!+('$&&)(*''))*&'$"")"'%(+*%!)!$%''#+#!&!%"$'(''%!!"&%%$+'))#"+!'!')$)(*+#$#&()*(()&*$)&%&'!'*'#%+#*!(("'##""(#"#*++'&"*++&*&*("#"!'!&)!')#(&+$!&*'#%$'(&(+&%+#(%&((#!#(!"!"(*$(++)&$&!$$&*'!&#+#$&'+$!)$%"'()"&$)+&#+)%$%*'(!+)+")!
@r1912
NGTGACGGACTGAACCTCCACGCTGNCCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACC
+
%H9A0A#2.:'&.0;%$#4-0DD58+=H*:7));>)7>7&3?*,./0:&5.F>'G:,D2;!HD&')4A=A,%6=&,,E$2E6=7C..(>+'8-C,9CBD4?--?,2',?A.9H'#E"34/#);"E19H<(!+0';?9B,C#>@8%*39"('&E%A5
@r1913
GCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGNGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAG
+
42H,6GD<9,%%DDA3,H56,;*&77H?3GB+G%.G=0E/H(@332A*C.1E15;<&,G91@98.6?D7C,'H3?DEA%12D<A-$-%F3%B?868H<=8.*,A,!H*::E@%&+--"G
@r1914
TTTTCCTGACGGGCGGTATATTTCTCCAGTGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGNGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAAGCATCCTTGCGCAGATTCCAGATNTCGTCTGCTTNCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGCTTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTC
+
@$GBH),@4++5?CEE?AC13>.,=!2/?8"A><D,A"A!8*15,%C:7797<C;+9+*98';'=")47?G16.909H5#C/A5:$2%68,8!0'/C98A@3E@.F?%7;)96@?:H9H&H'0<#%;0C<>C;/*533,G:29=93?@55.!H2ED=1=>F0/#AF.7"%#5.G)*7!B13#B-22/C=EH?/HG*&/8894A4<8"-1+83(D"64)&/G=FC)E=(0@B1'32"/.90'80!9,HD2=DAAH*E<>*%B3<4H?0@3BHCF/@--+:$4E",!H2?/F9C=*+!4H2G?E&EA7(?0@B("!@C9@,E,@F29'6>#%,:0)+@#5<5=<1/D(5"63+)HA7HC4$;G79")6=-'?0:&C?9%27=G&A=+59#;2A-ECCC:$
@r1915
GCAGACAACTTTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTNGTTGTGGTAGTGAGATGAAAAGANGCGGCGCTTACTACCGATTCCGCCTACTTGGTCACTTCGACGT
+
%E;62-DB-++)()(1%<;8;)G(;2.A.AG0(0D4G-09<>0,5%H4#D!1EH%9E1")",*D6"3,D61;)&&?'D'/<%&.95FA*1!AG8,#>+<7-4,&/$DF1$20.@*HAD<;,E%*>'C6B<7/&3"&:G*$H(D#C,<FG4)C;6>9F@-7/@F''<C":60/#30*!8:866G7,BCF+$"1-,C-=
@r1916
GGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGAACGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCG
+
$+)%$"'(+$#%&)!&'%*'))#+$*%(!(&"+)*++#%"###%&*"#'*%&$)+$+)$'))+%'"(+)'!$%!**$(+%%$#(!"'"!*!''#(*$!'$#")%*#&&('(%()"#)$)$%$#%$&"'+!$)!&%!$!$%"""&%(!#+"+')%&$#+$*()*%#"%)"(+"%#!$'!('+(&)%$")!*(()$$!#)(
@r1917
GCTTCGATAAATCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTAGCAACTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAANATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTNTAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGGTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGT
+
'%&*E"#66D?7>D:?,A*:*5,#(:1D?0)B/(=0-'<=49//*"=$E9E<@3.HB/06@$>315?#8*A6<:,-D.$:;.FC/>?24#F?5;5@>5-BD6';+?950)/3:>$"<5?1$8-H3##;7>61&.H+<5E@D@G*='G$8;0>:'"2<10E9=9A."/1$77/&.$@E764!:>B+D9626<H9*94?$:<;.:0DD6B9"'(C32"F>+?E7%BE6$"'.BF%4)&E!%)14)%&85,)?,-.01@"26=6(76:$#+5!$1DC*AH2F6D!&!))@9;6@-"!9;7,E62''5&*BH)G"657H&HG6="=#+7:&C<A(@0&14+9CD2HE""&434A!5#(GE0E8H4#H+GC>H*:9AB-;?$"<'/2)A#H+@2.).4>B*!22,*G$.9B871=#&E7D2<.649E)H!27G<-'CH8/=C.(,'*HCF+$BA#>*BE60
@r1918
CNNNNAANNNGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTNAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGNTTGATGACACGGATGAAACTGCCNGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTAAACNGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGG
+
$"#"!%'%!"&&%+)%*&!!)$"$%+'$($"!!$!"'**"&#*#(")!$")"%!"%!'+((&'!!(*)%$')%*)$&%)*#%)++*'"$#)&%+)!!)'!!(+)'&&*&(+#$)"#$#'!%*('#)'"&($((&&(&!$%(+%"#!"*$'+&#$)#'#%('%)!+$+$(!%'&!!#*+$)&%#("*+#)!&$%&$#!)%"*")"+&*"+)$"($''$(+*(&!*&("&'&%#!!&(&!%*(++(""'++!(%#'''"$*+%**((#'$!(!"!%!+!$''(#!'%"%*'&+%!#%*#)+!)('+*$"'++**+$!(+!$")*"$!&'$'$+!''*)+&&'+$!)#(*+#$$&&!*(%'$)!*"$!$("')*$)!%"!%$*%&('"#&'+#*+#&&$#%*"")(!+)$'&+#'!&'(+(%*%+&$!+*+*''$%"$&*!!+('+'(!''!!"%&$
@r1919
CNAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCANTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCTCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCNACCAGTACGGCCTTAATCCGTGGACGAAAGAAATT
+
#-7,114(/.!E-7.)2%,A?=7A-<$+21831?;9"0/D:G**CF5E?C@9B@-,D54D147&56==(>:!&397"'1%#>>$@+E:9?".-7!F9E7-*)2>'9&B170DE72D+GEB%5:2#),E.A:2<9*/'/7;!:BB2@=95+/13=,3?%G:(-E0&(,/C(HG>+13G4,,!8<E-::)@..1*!6>F2%91*H<1DB)7,5>D#,(@'3++8
@r1920
NATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCCTAGAGCCCCTCGTTTNTTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCACCCTC
+
!D;+<DF?,6&-;<:9!21(9<4=G947D&(>:1C+;H-&/?>4">B<&GG/B+>'@"E4H1C;C>('37%5F*+E/>7-A#**A?#";%&8//A662*:F7-16>E":>:>54=4C3;+BD6@4C$(<0
@r1921
GCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGTCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACTTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTG
+
>?/<5*5-"2F7<CB72':+%85@5,)E!1355;#G739"2E@4/*,*=(/:?CA'(2)%-:4=@9.(")<4<E1G=A,3HC4?>'9!?5(B8F=9!8)'=A";/DF(C22*/>276H%FH*H14&;<0D"8-D0C0+6*."H?$(2/,#4?2=$-;)6AD4CDB$'<%+D&.C0(4;7B.,,(A(8!+>9+A/@%!;E%#>15--5=8"(%H<85$)+'<-#"F*&@G?41-9=;!G2;2#&$$2#=38D#*.-6E.*0-5F$:85&G.)9+7%<HFD7*98*'>D:0<&D9F=6A)CD,9#7-=F4'D/G6031FG6E6*F
@r1922
GGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACT
+
)5;&).)<,)EA"3H>=A=&H5.07,@76BA+/=A!-1:>4#;G-?2*"9<A@=2:
@r1923
AGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCA
+
)+&!(**&($%)#%)%!%)))#(!'#($'(+*((&")$)%#+)!%#+$()(&*!!$)&&'#
@r1924
ANCTANGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTNAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTNTCCCCGCTTCCCCGGATGTGGCGNACATGACGGAGGATGACGTAATGCTGAAGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTNATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCNCAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCNCGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGNGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCNGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACTCTGTCCGATTTCAACNAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGNCAGATCGTATGCTGGTCCTGTCNAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACNAGACCAGNGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCNGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACANGGGCACGCTGGAGACCTGGGCAGACAGGACTCCGCGGGCATTCAAAGC
+
)'*#!!+"+(!##&%(#&))*))%(##")++!(')!""%'$(+(&"&')&$%%*(##+(!#))(+&$(+"&%)*+&$#'+$&)(*)$($+"$(*!($)''()*(+%+'%!))('(!#$#)+%!&)!$&!!!####)##(!))#(#!+"&%!&(&&(&('#$%&''$*$**#+(!&&+($&(&'"&&!*')##&"!'('$#($)&"*%+!#*("!'$+$$)'!+&!!&"%$(#(+')('+%+!++!#)*$$#)&!+(!*$$+#&(%%'#%""'$'$"&)+$'+$$&&#+%+++*!*(*'+%)('"##'$)$!))!$)!"%!'%%'!*+***'$*$#+!*$##+"%!*))"$(%$'!')"'"+"!"!%*&*(*&++++(*!''+"$%!'&%)#('$!!%(&*)"+##*%#')$(%'&'*+$!')#$+!"&+)("+$#(!(%#%#'"%*%*!%'$&)%#+)#&)$+)&!(!"+*)*!(!%(%$*"$*(&*$!!+$(!*+#*')#"!**"$(%$*&&%"'%'#%**"#$*!'!)$&+%)""&##''+#*"&+!")$#)#)'*#&))%!#+*)#!%'!')'$")$()$+'"%(+!!$%&)%*"'!!!"#*"%)+&+$%&##)*#!!$""%)++"(+&%"$#%('!#$&"+"&!%!$"##&!*)&&*##**$$&)'$'&$%$%#&)%"#$*%$""("$$#''!#(*%)*!")"(&#&)((''%'(%*&&$$*#"$'&+$&)%&#$##!!(!&+&$)$!(%*%%#'!()"&$"%'!%%#$''$*!)%+'!+!&*$(*$+#*"+#"%#')($!&$$%&(()#!%%!(!%"$%'%%*!(&$"(+*&&#('&"&%"(!#+#+(%+('*$'*#!$*&%$%$%"&%((('!''((!&!''(!+'(")#(++&"'"'&%")%')*!+$$)'&*!(+(**#)&%!'"!($!*$"+$+$((%)("*$$!+&!)!(*)%"'$!#&%$'&)()(&$*'(!$#'$%&(''&$+(+&*"'!*(#*'%!+$++$*%)&!*')#'&+'+#*'&("*&"$%))&#$')'#)#!'+#)%!$!""+)%+**#""%#+$!)&)#%#)#&&*)*($"+$&$(*"$($+$$#%(*))+%%&&+)!"'*'&)+&*&"('#(*!*('*&%#(%!)*$'#'!"%
@r1925
TGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATNATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGNTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGNTTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTNGGTCGACAGAATCCATGCCGACACGGTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTGATTCGTTTTATACCTCTGAATCCATATCAACCNGGTGTTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCANCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTAACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCTGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGT
+
F&A;!!.5?#@52$<8B)?$=&7?F;B$E!323764;),(-:D09*"),=8F,+)1,9A-7/-=#*;>69H(0><B)=D&@H!D=4A#.AD.9G0)+2#5H/HA&7H;8FHB,@B.3"8+F$G,';H2&&$0G/G&26.%5=762==0"(7//C<(&:C*?3?D8(%>2;'3<&4*@B47210B1((BD!.+6FD:C<!?,05-;)G7&1;+)3FHF?);G5B?-8',C5=1=?0B,;:9#?E7D:209.2:@?.*B=,%H/-1G07A,;D??E)5"&$8&%1.D/);?>&/866&70.:99B(EA@AD=*;?:9%@8"4E6>-D@F<0%4G<A:7!!;*.&+HE0"-7(A#-H1$!9"4;''082-2:F)'7(=B;)#<H6&$,C@%9D(HHD*B(!<;(B"C(/*+B,?<-@;+3#E2.G0D@,-"F2,84'&%@$!@'B0(D<@#=&)8F!6--3-1E:%2!9$.*==(&76!#(/?(#;,/DH9,,A,00+)!9C)'HE3?<0='?>6$87D3+2)&B;;=";EF52?/.,;&C1/=6D>52B45&HC<G>E404+",!B-7%><3357$<.21=<0D=&<5;,20A>/@))5-3;<G**8'58))!.B1*+9AC2,"A&87:#+(E+!9!+!CB<3%C8&#!!+@52.$,34,<CB/C/()D%.G%C<3A&=21/B.<%1D<+*:4E/F+?#$*6"7?+G"<C6!7C@/??D)8*'!+)$E"02+<C@D401#9*,C,?AG9#7"4:9/>A'<D2+G*7095/B+A7%H)"!.+<7-"5"%A?%1H4$G!@.F,9'9:G5>5$&F0=EGGE*(>,::>>F:''"4!4"@0?7H:/=*%"*3C%HH"@HF6,+8)86#A+H>+'.)348<@2$C%468*EBD<.:%@$*B7"$>&!<2B<(2#=7488@
@r1926
CGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCNGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGAC
+
D@4.F'EA>4(BC68+49#4H?:"$1.5?(>>HF=FG(1:5>+=)/!<5?GGA0?#.G/E0*(.?DG2/G>$F,3(5A>&1,:!F(!!56+B4/;&:;2H)782"43C:7?;<13B;*3"2@*D!?D-F"*$E=H0+A(A<5E?FCF>?&07%01*=!.?0'&F6,FB'4E7!(9.G-*#0:=C6@9$+FC-;BG@-*@28%CA5G54!A'=1-4+**A0%F:#D5+-($F0@G8='?<*3/$B)@H?$"8&:?4G+G
@r1927
GCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGANCAATCACCACAACCTGA
+
>(4H&"<.4H@4-/+B4F&"H>+$$BH/71H3"/)?9'ED%"G2<6&D"*DC>C.%(3)D=7G>@+4;,H4&E>2E)5&2C+1/9*69F4922<747$17
@r1928
NANGNAGGGNCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAAATCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAA
+
$%!*!')")!$'&#&+$!!*&%(+&#&#+)&#(($(%(**)!(#)$*'%$"')''&"%+#%"!*#+($+()(''+#+%!"(((&#$*+)$&*($#*((''$*$*%%%!#*"#")
@r1929
GGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGAC
+
3:.6<;>C)#F$.)5#B-4H7D/+:16?>&87B(2$*:-4<%C2:7?H(3:))@2.)<$D//&BD#)5/7(38:!H>+")2(44*'8"F/6H-@3.5A'64(B<+:>,1@@D'>-6,8<$4-6E68'.<?!H?<(9?(/9>)6F:8>1<E@@8!2C>F=.8=6$>B;A8G74,)))@6;.:14(E43E93=6@.)3:25"$G$7'@927?!@A@2$G237
@r1930
GAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCNCCGCCACCAACAGCCCCGCCAATGGCGNTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGNACGGGTGAAGGTCCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGNAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCNGNGGATTATCGC
+
F?&A0&95//33=/91<+,13%<3-):#%+A//GD6)BF'(";1!;2A@%/%19:.&)%'!6--55B!()@$AFE.'HB;:5C11+8"H4A24"H/?.(%7&3&*F/9(=25@"<F7D#(F$=78)!F$-$>8*/@CA8.H,FA9*D2&"+)6&9*0/'A(E;62"5.F>?01%#B.A;.=H";/A$:D,$9))10#%9.*&F$-+5EC1=C?;A&0(5*>*C%,9+1*&0,,1::H7D#A.<-0/A5AH>+"-6#<<G68"/3@C+/4B6E.A($:/$@4C"6E0(6FB.H:+=F7?F=6%*@%&;89ED&)'7E$+BE,$6!GC@@<1.A'('4'+HH49A@(=E*6+G-3A/6/F<5$.@)B11B@8DH/G4?7-79<3A>5/=.'@.?6;/B;*D'0B$*9+>=+,'5DF+<":>A-.?EG2)'<4<6--+H7A6975;!=B9-<
@r1931
GGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATNCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCT
+
8."=,BE?1.#"/6@%+2;.<E(.:7E>$G!):)(3*88B95*@-FE8.**(6';G*3H3A*6$4#@"@'+/&)5/D=2>+6F6+(G1(!>-@$)66A7C9=%?"DCC
@r1932
NNGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGG
+
'!<<+00G6(."E>/'B-'*07<44=2?2!?H5?A?A<=B-=(8F)F
@r1933
GTGCGGCTTNGTGGTAAGCACGCCGGAGAGGGNAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCNGTATGTCGCCGGACTGGCTGCAGGCAGAAANGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACG
+
F0%6&5,1G?53=A7=B=E?=D!0:BBB1;)&C71/H3-',(@;C:,G=39G&;A)F7$&1A0?E3A+8%4AE1,18?1:"")HA3#46EA$G*="2.&:47CE#,;F!@$*!4;H07960D:+"7,+2$.68@#.'@B@.+';F0$+E#-6)F:$(12!1@*:!&-.D&1B0=7-02?-HE*2*0C4;*79<(=%@3'=#,4(;994G)>:C@2<"8=D?/1+!'F#3+!F2(>!C),D8-<HCF&;@HA-7#%.9*GE0)3624"0G730714'>/2,3H376"C5(!56+&
@r1934
ACTAAGTAGTGATGAAAACTTTTNAAATATGGAACTCATCAGCCTCATTTCTAAATATGNAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGAAGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGT
+
7/-A5&3G<!?5F89DF>9(-'+E;:!0=B5%;-AH4<E+$&H?115C)'55D$9",5GE%G1(,$0DA!C8*9@4>%9(HEC,=7?3A?<&>3D4-8%*:'+;>6,::6<)&B?(6E2-F.H5?(C9<=+@20-6ED>)(,#-"H3,08*$4;""/<&=/,(?%-=(C$(8D>))H9A8!)BH'/26<68G#,H%1)049*E:&1)
@r1935
GGCCAGCTCGGGATCAGCAGCCTGACGGATGCGGTTTCCGGCGACAGCCTGATTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGNTGATGATGACGGACCACGACAGGCCCGCANTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGCACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCNCCCGGACAGGCTCCATCGGCGTNATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGNTGGACGCAACCCGCCAGATGTTTGCGNAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTNTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGNCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAAC
+
%AC>=?)#;'(4CA8C*0!%2)6-!-87ECB"DC+;+#/5A%87G88C+>)(D7#8D2158#::A&.))+26D4"-?7<G)"+=(+4=8A<(5+>>#5=/"/%9B7!C"#-=84,.D:&&25);."+H%1G1%'E&$3B&8653F6<102AHF)D8<)/E&*0.B');2?GG,3C))+<;1;C)?E!=7"('9<2"65<C3E4?"A79@+;@:1-":112!AA$D0!+ED$E<2"0.(4D<?=!D'(;'$$2>A88%5,&(0+)6?++C2C(.,A59$6#=/6%>735B@</B)4@H'+D3C.:*:6@C;%*)5>7H2>((-)%)8*)B"D:6(7H8&-H8426E,=#)5<5?C=;3-$<!*#@2>$C<=D&6,6+):;"6H@,D"E;55'""';E0:C:%<@++#+5+0E@16>"<A)F.+8ED3>8<+HGH<A6A7&/B%*1/5G!;!"**&:7!:"/C2%><00*>E?"C=$ADG">D'-31AB$51"F=$%"DG":31A<(0*7,.<?=)-984;,8>-EG=+("@DH!:8G$,%">.6G,961B0/<+A%8?$CEF:%&36&+H0@7%,/F05%<;(*6(8;%&G0=G'/3.%FCB0;/$62'%H+*#-$@A,3H?C@(2F,+BC'8E56!%8#!G4$:D/)GA5-F+G<=59F3(@5/#/;17%)9;5:1-,.)0+3@0)5E%A-%6/622D$.>>8?7)(+1=/$08(%F&63:&?=*H;4=+B8(A:.52=4$#G<!&E<6*H#9=697(;%>C:7:=DD44A7DBB.+13;"GE+!&+,=:@7>&06312#?;:%)6H8+?E;G,%<7>223A.<C?!+?18;:(-94E
@r1936
GAGTTTTGGGTNTAGCGTGACAAGNTTGCGAGGGTGATCGGAGTAATCAGTAGATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTC
+
GB;+:4E?1)-BG<F)H($3581(.!#'A'>0>)7.0,$%A<?'.A@D'+717?E'*'*37D?;4,GF4=G0E&2F>$5@%-8<!#-.9.@;@/8B&+CDD<;)!E&
@r1937
AAAAACTACCGTGAAAAGTCGGTGGAAGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCNCNAAGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCANCCAGTGAATCCCCGCATTT
+
:<9$!7:!?:H)/<;7A)G!/$=0F9A3,,F$?7%-EC5=!9="-?7D86.C/G(.2#</#+?;:G;%6$>8$/%-F8G:;/G>9A('=>G%"@44$(*)..?4!21"7=>29@7$*$AA&2FA.%85.@$/D?;':*F(8:-%/.*//.<-&?%&2!<%8=8!H1324GEF2*A;D*6HH?.'A/&30-CH&%:BG"7':9C)$&
@r1938
GTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGANGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGNAGGCCATTGATGCCGGACTGGCTNATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCANATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAGCAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCATCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATT
+
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
@r1939
CAGAATCACCGATTCTCAACTNANCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAANACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGNATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAAC
+
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
@r1940
CGATGGTCNGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAANAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCA
+
-B3:9'==D7-":6#0);E6:*78?@3%%AD<5<08,2-A/D&G3?G6B:#0E(G)-244.;%8+.>%3(!(>5.+;"0D=,=GC=<D"08'$2#5;(7A@+$2)"5C88F-66+#2#/C;!!B8/=?$+FB*&/20*:0);2(>*.31>G".&4?'!G)A6E+E?7;2=A+)'9,D#BF*B5;FBG'>3@,A$4"@:7!7D552D47.:).+<<;:H"5),17#>8$D'0D%(%;AA&&"H(96$#-CDD)#9/&!'56.<8;G2;..E(E+3!=A:E@&??'?/*=>D'3!4'-?2<C3GB-6BCE(DHG=3B=7.,(#9<:A#=6"EA:FH8GEFE4
@r1941
CAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAANTCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCNGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTGCC
+
#=++C3HB?>#;(9G<8@GB:C7*612@!4>,?)%;><'+:(.%,>:==781-$-5D!7H#D)C!-C=.G;/?2B4F2$;@28'7?806?4+>D8?#E,&(5!)4&3<@F8$#=E.%(4C%!?082(<DC!G+8*8"CB;1AA9?FCA6D.4<.?.==1<CC<6A,=:)0&)G1@?9>@'4,,:&;!G'!9334.4:<9044-,7637!.&9'2@FH(02$?@>?,-3&428@5!C3@@#E&.5BB.-04B+$"A="G*>2)/;9>=)01.4.G&:G:2-74!/C*D3(A<F346$&35D$?45?-:G)B:'144;6!.=*FF.*&.<+;)!!+%!B1B$">=!7$@8!=7-5'(/>301!@),!FA$)%?2+8#A<*%/FG0'$.#>,G;#;=/,*4</?@-!$/,6&%<B!59DF16>2812(%B8+F7?
@r1942
NCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATC
+
%>"5+CC&#HH5)$-D;GG7%;D)"$G;&"":4+83=&?3CG?D+9F$0#*>0H'B<>/#!5E+%8%9E*CBF<1D'469>29)G'1"3=D.3=6A@B+D7,*,1&""BCE6)H&&A;?GH#5D.%".?1@$'-<**;A/>(A##F;A#9E%%+/3'+-+3A!=<&+;*-A'H
@r1943
NNNNNTNNNNANNGNNGNANNNAGTGNNNNCNANNNNTNNGANGNNANCCGNACNACAAAACTCGACNNCGCNNGNGNAACANTACGCNNNANNNNNNNNTGNGCATAGTNANNTNNNTANTCTCCGANNCAGTNNCTNNCGCCNNCNNNNGCNGGNCNTNGGATTNGAATCGTNNGNCGNNTANNNNNANCNNNNANNANNNCCNTNTTGCNNATNNN
+
"!"!"##$#"#"#$!$#$#""!##"!""###!#$!$!#"""!!##"##$$##$"!"#$!$"!###$""!"$#"!!!$!"!!"#$#!"""!"#"!$"""!#$"!$"##$$$$$$!"#$"#!!"##"$$!!"!$!!!"$#!$$##$"!#!!"$"$$"$""#"!$"$$#!##$$!#!!!$"$"!"#"$"#$#$"!!!"$$#!$!$!$$"$!#"#$#$$#"""
@r1944
AAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGATGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGNGAAACGCCANAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGCTTA
+
F':1>FG+8%C&/4<7#A;'/<?>')/51.47-<<F4?@C%!.-E5;!&(9.*+?D"D<$++B0.='$=/$.'/8,C(1)/>!@7&B9.;.5.7!?>F>/3;GE.$3;34%-B'30:@CG00E7>58##>4>+H18C8%*5.&(=9-!="(#1:66)D=D2!.?6+"$%,,9!7?3:F
@r1945
CTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGATTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATANCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGCGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACTGTTTCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAANCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCNGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACT
+
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
@r1946
CTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGTTGACCANCCGCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACNCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACC
+
6C,>$*$B%$*/).21-<HD/86-C30&!!#./A&B;5E&:G,C.9C@%(1CG9H*>>)E1@:9A"%'%G88=(C)5?39&#-(6,FF(%C?&2A0/;:04!B9;>00E=18D2A;3@;AA9'.A!1?HBA5A34DE+:).!9?;3;3>.:=8F=10BC6;@.#GC/?E?/A4$"0E/6$H-E;5H'25!&/,%>-3:<-+7406&,**@6:254"="!,*+<-8(?
@r1947
NACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGNTAC
+
"/E/C*$;D;+4">A':A!570AG1>6H2*"+$-E9$/17!#4%/1C&@GE'/4
@r1948
TAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCNAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCT
+
H!$-G:6(5@55<9.21,=<F,GD:3(?5&7;"*A=A6GC9(B5"!!+G$&=:6(G,CH1:;2)<-05-;H:C8*G=88G3C*/E+9B4A17!:"-73-"89#5:.0=68F7?A4?&%G&&#,"/2H-,A6GF,CDEFA4H?E!7&+D6*=<=)(,)$<?6=!8=*F#5&(&9.!9*2E<)')-'D83A5B"5,G,B9&C=D:05+"EH+701=>8,+*2F.-H""7,>66/4F26C-+*E492"*,,G2,%8GA1=#29>((2$95'89<#48/C*'3=+!7?7-;6DD/*B%*:1"74&'9H!%$*7DD=+=3
@r1949
GNGTANNNTAAACNNTACGCTGNNGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGNGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATNGTGGTGCTTCCGCTGACGTTTCGCGGAANTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTNAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTNCACACGGCATTCGGCAGATATNCCGCCGTATACGCTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTNGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGTGTAATGTGTGTATNGCCGTTGCTGTCTTTGNCGCACTTGCGGTGACAGTCNCTCCGGCCCGTGCGGAAGGT
+
!)&(#$##(&$%''!&++!+"'!+**''#%+")*$%)('*!#)(''!'*'(&''$#$'%#&#+#$(!$*+$$&#%&*%(%%*%))''$&%(%&&*'&#*!+&+*'(#%+'")'*&&&'%"*"%(++!$!'"&)*+$!)&(&+!#'$)%#'"&$$&!)$$""#"&##(%&$"$%"+"!))#*(!"(+'+'%!%&!*(!+'!$'"""##&&#$*$$&+*!)&(!!%&!($#+'&%)&#&"+(+'"$%%!++&)'$'(+#*%!)+(+%&&#$((++#+$*%#!*$%%&!""'&$+!((*$+$$$)*!$(*')'(%!"$%$"(#&$')#""*#%)$'*%"''+$&"+$!'''($"'#&+%'#*'+!$"")($*&%%"")*)#(&#!*&'!"'%&!&(#+#)'*''))*#*!"''"!(&+*"$)%+!*%+*'"#'%%#+%(&#(%!'*+#&%)!#*#%*&%'#%&#'#(*)($'+%$+&!+%&(&(%)!"&"(&!+%$''$&%"$$&!&!&%'''!(*)!'&%+%)!%)#%$((#*"&"*!)**"+'(!#+'''$+"#"(%)$#%+'$&"%'#!$"'&*$("*+($%%#)*""&*('
@r1950
GCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGNCTGAAATGGTCATCACAGTATTTGGTGNAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCNGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCGCAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCNTTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTNTCCCCATCTCGCGTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCCGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTNTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTTGATGGTCATCTTTTAANTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTNATACACTTGCTCCTTTCAGTCC
+
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
@r1951
NNNNCCANCGTGACGCTNGTATCTCCGGCAGTTTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCNACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTANAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTNATCACCGGATAAATCCGTGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAGAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAANGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATNAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCANTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAG
+
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
@r1952
NNACAGCAAATCCCAGACCCAACCAAANCAATCGTAGTAA
+
##12A<4261!($%H"/''7>/-B$<D:62C6@/1=D5=8
@r1953
GCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACA
+
/;*2-EC11E1>@F!6$G12$*,=3;=0>B975H>C,D'E)>B908:A>
@r1954
CACCGGACATNATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAATAGGGGGATGATGCGTGGCACAAATTATGG
+
%/G4A>9(+D!**9-GA$#9#5+2F/)..EC<D+#3)/)@1:=&5>G8:$+H$C"/3#-%.9G%?"&%%7?815@)5;D)
@r1955
ATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGNAAAGGGCCAGGCTGAAAAGGGC
+
>.A8B9$+("39/G;.C:<%!#(/3(H;?6"0*>"(?G)'8/E3?'>7AA$9+(>D"E:H$?*<,6/4&9E:<B:(/2@%7
@r1956
GGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAA
+
0)3@HC2@='8%-7%.H&:5-?!=!&8;&(#0F/;2)?DDC#&)=
@r1957
ANNATNNCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTNAACCGTCGCCGCTGAAAGGGNGATGTATGGCCATAAAAGGTCTTGAGCAGGCCG
+
'""''%&%++$!'(!'(*#+'$'!#%**#*&!$#+(!$!(*"'!*$"%($!'+(+)'%!)))!$"&)()('+%'+*(#)#&*)*%)+'")"&*#$''*+)"$%"&$$
@r1958
GGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCNTGGGGAAAACAGTACGAGAACGANGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTANCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTCTACCTACCGGGATTTCATGANGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGNAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCANCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTANTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTGTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTAGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGTCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATNCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGAT
+
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
@r1959
TGGCGAAGCCCTTCTGCGCCGACGCTGNAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCGAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCACTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAANGGCGCGCCATCATCCGGCATCACCACATTTCTGCGGTTATAGGTCCACGTCTTATCCGACGNTCGGTCCTGCANGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTA
+
;C(,:H-:.72)>-1!7>4!(8%"E3H0$(G*17'!',<HCC-#59$<@9-GAE;5H#@,?/;$CE&-B$B;#C:6>@%1B?;''9'=3<<(HED@1&6.E0!8*,$5$G'//8=#!2:&@,;3'H1(3519$3@;/">;.G*+*F5?!F?;#$@;A*?'C$:H5@73(%A;#+-D%B/0G"B6B(34H;*H++-.<)A613;*0>-;=!&H%"'&&@?<@%<FA?6"F!G>#)5!@(1!"$G?6@AHF=F&''4F9%8D(-D$FF)H931;$D9E>493((3GB18(0;)!%.!87&"+"2;A@$.9*3!D(3B?=/.,*,8(=F-4>=/H66H$/&5D/?<++,G>)@6$'0,'%%4<!G)@:,#7?271$5$+&*2"(/4H&:A,C?-66*G.:'H2:B>*&,#$4(.(<%F%:%*,6/&>B/C.'8#A31-5F
@r1960
CTCCTGTAACTGCGCCGTTAANCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGNGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCNCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCG
+
?A(18BG4#FC@!)D=/&G&)9EH*D7-?8$9'7E@7</:0.51>,*F3.E1:'9"(!:?-D",)9/2<93@@*-B>DG71E3?FBC8E@2B>*";/-:**7%@4GE$)$,-#DH&."C9.;,3B61A4.#G;9"0<$C9!1+$'E*C=?)>G,4G0!+7>9B''36.&$,9%G)76(D'?G,4%>GCB/B<?#3F28=&1,3A45=6,:<EACH@!!E074,#34"08.#,CA;6&%2<-),)47>?D;G74C5>&'7>"5;EH;?%)%'.*+H!)';?>%.?(3>H/7'+/F?%<
@r1961
GTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCT
+
*8<E9@.GD5E,/H9"8.8BB4-4:9#>9A*7$@E**<G6FACHD'*7,9%$!B."?%:<B7/C3!2&;B/(!0.559"-02C)$G?5*?66F.">9/43A&D-/33=G0$GBDFD(8&"H+GB0%"EE/8-8E7/*2%'%9@"AB,(/>$.125=;'>,=,*-.!$(;5E6;*1CDF#(*:1B<'2DH7HC$&&-E-H:(=+D0D.)83E+:*H0,
@r1962
NCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATTCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGA
+
#G&HF$D:<;3()EF0>A*=(>&7'<3=B,?80,?;76@8**$5'!E*:@A.B435?+62<"@H!BF?E1H24'(4&<3@@E8<(8A05CHAF1A7,?>.;+$!D:CCB<(E-D1.$G<14)-2/.(3H#8B7:@+--!!9"1-"@6C95591DE"5$%#++>'B-+!4G@(FB:.?,E0(!>$?E=G8F;@)G;'"$'-(::A$84A(
@r1963
CCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAA
+
@1.+*2%C=6H:/;@4%&0C?A488,+2&&.B=D3,;=!8538?!!0H:8(/8&AD=
@r1964
ACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTANGAAGGCTCCNGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGNGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGG
+
BB'B3&4+&A+H:<HC37>35E0.'&@%#585;@5#==)G3:641>5<C+1F,7&!-)F?H!HFGFG+.;4!GD:F&<F!$>>.6G.>*/(?G2=+8,810<"7(C25801$:=1E:G)<C'+!)=&:-3G@9>D:'%C+@+5F4%,25E<(@5866+@2!.5#/E">CBA+;E,9,$/0A>"):C;'0)8;6;,:F52.D#.;B=&!,1%A&"@);?78,D)A'&E
@r1965
NCNNNNGTNTNCNGNNCNGACNNTANNNTNTCCNTNCCCGGGATACCNNGGTNNNTCATNCNNNNANACTANNGNNNNNANNANTANANANNNNGNTNNNTGAANTNNGGNNNTGNNCGCTTTCCCCNGNCNAGNNTTNNCCNNGATNNCGCNANNNCTTANNANGNTGGAAAN
+
#"##"!"#"$!"#!$$##"!#####"!!#""$$#$!"$"$!"#""!##"$"$""$!""#$#$#!!$!""#$#!#""!!#$!$""$!"#""$!"!""$##"!"#"#!!$!##"!$!"!$#!#$#!!""!!!#!!$$$"#!#!#"!#$$!!#!#!$!#"$""$!"#!#!""$$##$
@r1966
CTTTTTGCCATACCACGGGGCCAGCGCCTGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTG
+
F-=3'<5=!!"%D#B=?*(H"*;<A&D?3<#9H5+50(H4'-$1=!A,0+69;C4'6E;B-3G)E%%/6/+"97-"19%&<428(A;78'2%6H#E5C9"!2E++""&22"4D?.A,E-77>@*3+
@r1967
ACTNCCNCAAGAAATTNNNGTTGNANNCACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTNCTGCCGGTTTNTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCACGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTAATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATCAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCCACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAAT
+
!"(&&%!*&&!*%&")!#"("$(*'&")+*+#$$&')#$(""(''%&!!$#&!!(#*!!!'*#'%*)('*)%)*&'+")(*!"+&!%#'$*$)%#%#(##$!"!&*!)*)%+$++%!&*!&&$+"'!(#$)+"!####$"%&$*$%&'&*!!"$!*"+((!!"('))(+''$%+'*&*+%#+)&!'(#&(&+("++&'(%)(!(#$'#+((+('*#$+'#+')"#%#"'('*'"%#"!')%++"%+%$'+#%!)!(%$*(+!+#&"''&$"")'!$$+"')))(!*#!%*$#%!"!$+$")#&&""$$'%'%*&%()!#*)#''"$&!!*+#)$$''#*$!""!(%$$#%#%+$*"%#'%)&'#%$#)"!+)+))(%(''&(*%%''#%')*!)#!#$&(&&*$%)##!"##!!))"!"*++(+)&"(&+*#(+$(%)"$++'+)"(!&'&+&%*#$"!%#+''*#&)!"!&%"!$"**')"%$"(!#+#'%)(!&!"$*"&$$"
@r1968
GGCTNATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAACGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGA
+
G%<:6H6G:E,30)=23A=H7%>,/:5F/-4#4@AE03-C@"3'H)@26'+(189)D8:=</=D9*8#.D4"43D99;3D+?E-!7(2;20')?;5/"'=+>?07);!,.&B=/A):!A+G'D+?,5*$9'&>G+5)('#$A@24,%40DBB<$2658.0GGH"
@r1969
AGNTGGTTCNGCAACCAACAAGAAANCACTGGNAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCC
+
$)"*%#$*'+)*!$+()+"#+$"$(#%**$*!*!%*$'(++)!')"*)+(%#!)+(!+*&%)!+)'$'$)+)+$+'!&(!#"!"))("$)#+*%!*$
@r1970
TGNCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTGTTGAAGGCTCGNTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTTAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTNAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAATTTTGGCGACAAAGAGACGCCGTTTGGCCTCNAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGNCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTANATCTGCGAAAAGACCGGGATCTGGACCCGTGATNGCATTTTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCNGACAGTGTGACCTTTCANATCTGGACAGCGTACAGCCCGTTNACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCNTAAACACCACGCTCGGTGAGACGTGGGAGTCGAAAATTGGCGAACGTCCCGATGCTGAAGTGATGGCAGAGCGGANAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACNGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTNTGGGGATG
+
"'#+$!!((!&%"&""'(+#%(+%%#)+'"'*#(#%$$#++#!+)'"!#+#!'$'+("#(!%)'*#!%$'()(!'%#'#$!%&'(&'"##$()++#('$**)($+*("#(""()$)!+''+%#&($$%#'#+'#("*))"!"$)*%#(!)#'(%*&+%*(("(**"+'('!((+#&%%"!+'!!$((%(#%(+#$%)#&#!*&%'"&%#"")""&#*)*%$")*$*&+$%"*%%%'+%+")"$%%#''$%'%$#''&)%*'!!#+&()""'+)'(!)&#&$()"&+!+!)!+&!+&%%(!(*$&'%"++)!%+%)$!+*&((+"('$)!!$'%""(%)*)&"!)&+&')#"#*#*''%"()'*%&$%'#$**'"!(&%#*(%*+%(""&!'%)&!''#%*!&*#"'!"$&*$"&'#++#'+)*"&(&$#&)#$)&((+"+%('+*(!)'(&'&+(+#*$$+"'*!+''#+($&#&"#''%$!&#'&*#)*'+&&&#%('"%)*'$##&)$+(&*&%&&&!&!(&&#(''*)!"(&!)+%+&$##!"""!%&&!+&'!"%&)*#+("+&(&"+#$&)%*$&%+'")($(!)*)')+#($++"()#+"!$$&"+"%%+)$$&)"(+&"##&"!$+#&!"$(&*%*'$''#'(%%"%"+$('"*()!+$++)'%$'%%%#)'*"*&!%)!#'"&"&"!("*#&))'$$&+"%($"$%+!#)+"$
@r1971
CTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGAC
+
2#//'9#G04C+(:?0FF-2(H)4-%;'9?:8%:$(GC#++()(#1.,<A0>DED6=;@/A9
@r1972
ACGGNANAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGNGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGTACTTCGTCAACGGAAACAGTTACGC
+
)!($#'!*+!%#((*!((!*")++(!!$)''*&''!$%$"!%&)")$*''"&"!*+%(**"(%*&$(%*'!((#$$$$*(&*)(+%+%!!(*$'&$"!)'")(%(*%(!$*)!!$!$!)&$+%!*+(!'"%'$"$%'%*''"%%&!")"(#$'"&(#"!!)+(+)&")&
@r1973
TTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAANATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCGTTCAGCGTATTCAGTGCGTCAGGTGACNCGTCGATAACATCTGCATTCGCGGCCAGTACAAAAGCGGTGTTCCCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCNGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTNTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCNCTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAACCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTNTTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCTCGCAGCCTCTGTCGCCTTCGTGGATGCGGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCACAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCTGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCAGCACTTGATGATGCGTTCNTTTCTGATGATTTTGCTGCCTCTTTTGANGCCACCGCATCTCGTGCTGAAGTGG
+
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
@r1974
CACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAA
+
'G-F4;)G"4#?%,6F08=5"7H"3*(?@-2('/#<G-F:"6<G+AD3;6D5*/-<;'?7@410:0F+87<$3-C7+1?C/.EB09E*:<(AF/-9)8%!7??+4#;!2$:9,/,A<%0C@"9(3)0>CH#;9
@r1975
AGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACNGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATNTTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCTAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTNTCTTGTTGTTCGNCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGNAAGAGTTTCTGCGGCAGTTAAT
+
+?+':3BG4A@'$)36?8>B;*060/@&5'(<74#G'.83*>24+'$D@8A#?'@3&."@3*#H94#&=?&59E-&8(A>.EE"6')A2"3H9<777=D>,5-G"$1.=H0G-D?(<19&FG%>1771$!:11,4/C;10C%+B%0)/"F0F-F)(:.3D(F72.3E)BB;@)EG<G+H@.G1((4;>$!2<8A7@B(#=H&G0*CA&CF:/==C>'350.A*>>,)DH*CC49'.DD7D11&F62>!6)31"$#9//3/C%<%>=0()@"E3%2C0@H@,A+*-@G$8CB7)D:&H2$F2HF0;)B,'(.)<?(..#,';*2H?*-18-<G=&8"<%-#)?EB+"2?75;#.H0/>1EC!D+G&"BD7E8&A,(%),:0<8&G:-DFH*C%?:4!
@r1976
GGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGATCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTACTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTG
+
;+001;ADDDA:/3..7@F=E,(-@:!%G6/3H7C/DG,28%(H)5B<63E5/H@&:&>')EE41C:G3?=B?:+1!D4.9)5'C!2A=C(C:G@>H*.F;8+"*+#9F01(CBH!)(02,%=%;<@?;$??139$-:9H8>'8CG#*7C>)8+/3B+5#5:HG-=9%-CA*DE992;GB;&7GB:4?ED227H@H(>-)H<(:?2G3A#<;03<6
@r1977
GCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGTAGAGTTANTTGA
+
1EC>%.)+8+63=:5<)*7D,0B=4?8%2D/((732+$5&D(0"11;/,'=/7)-//%,0>$D,&<)9312$#H&C4$8!GC*+86C@%*!;8-,:E3>3",/
@r1978
GCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCNTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGNGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGANACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTAGCCCAGGAATNTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATANCGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTT
+
+&!(%(*+*%*+%'#(&(+$(&("()'!+$%%))%"!+'*$")()&+)#))()"#$!(!$!##*"&$+%)!(""*!"+&&#($%!+!+*"!)&*+*)&+*)'%$!"+!!%$($(""!#$(%'(+$'#+)%+)#$+&!#+%)*(%*%$'+&#()#*$$&*"+%"$$!!%(!!!)$!+!$#%)#")&$"+%!"&#'#+)&&"+)%)#!''$''*(%+%+"*'(!&&('!&"'%'()%+&&)*%)&!(#)#"!#&#&)"*&%&()"#*!*!%$%'+%%#$%'$'"+)%)+%))""'"+*%)(#((%"%)#++$&"+)$"!+'$'+*+%&*)!&(#"""$+!*&*'&$)+*(#'*%*%)#""+*'**$$)(""+&*!"&(+))(#
@r1979
ATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCA
+
46$6>D,%B!H.7/&-A?B2E*1*:%-!655,(?BC=%.;3#=@+:D#D3A/$AE<*G9C;%@A'63G'9G?(:+"H@$91$-C"H#*66#>3@G(/76?:#E;2??.29!E$1!+5"
@r1980
TTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAAT
+
/."C0*(;9/4(9/C>A<20$:AH8#;-=0/"-7=6A<054<1G*6@+FA%.7#F*%C4:9--&0/='(CEG(D*0((.D#<'11C.;/5>F#
@r1981
AGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGGTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGG
+
7@H&'H-14C*88/3;/97!H5D7?'!H5<->!;FD/+2*@!F#;#:?)<(A"H%'7BH6<-/F-E3@@,E
@r1982
CTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCGGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCNGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTG
+
)B;BBC%B$:?!H=?5D95,3?%DEA544C,=#9:/A=+H&9H2296D2)+'5B?&0+FC"47FD>F63?G!09-.A+>+!47;?C$%58>>(.B$(E92:">*"<,A-6,>74;E'0>4;=1B2<1=(>(D+D,6%=5*E#+<=/?#;5(6EB4?(&F*A68+/*"7DG<<HB#41E?.$/5#%A7+9%H(9
@r1983
AAACGGCAGGCAGAACAGGCGGAGTCAGANAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGATGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGNAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAAGGTGGTNTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCC
+
@(C5A?$=/C")F+";%*,+?2G/C:,&12B9::5*+F!*!8A%E0!)#':6?A#H+/$@'5.=A@(B?.(%.@"4G/G<DE890G"B"9%8'+;65@E>D;:*C""91FG3B!8+E>"1+7:?/"(5;?/D.!1':BB543;5@AABEH$.@(;*;1&9%)-=+"="5.7,3'54-F$+B4;G/HF*48%'"+H$>".BD)B30H*;*?5'CE?#A+#B.BD2(4'G4=!%H*E-!75H"33&.G"H!D@#:*>(*9&
@r1984
ACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACNCGGCTC
+
1,@+DE.E%,*!(;37C1:3%*--?*6%%"!H'03,8<9*6%'!@4/(+0"8AE<G$2!#1=:)2B32723
@r1985
GTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCANTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAGGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCANTGGATGCAAGCTGCAATNGGA
+
<"H)$D+6(,%9&9"9<HH6*B;>0?-B<>=6,CH9:?<3(0)=H#8GB8;F@(&"-4(8<;H#329H<E"H72:!4<1)+5";>?B>55F8,4?B(,'',B)::D+6BA'3("B:=*&;'/4?58,4(9>%-;<=@G%F1'F"@<>+A##:A90.!G">F";$0)9.9+94,*60"+)D5.>8-#F1?$;>F7*A!9-<*F%3#A<B)/$8/471',6F?C&%'%E%=&?;%.CB@-A/@74!2.2,62*9>F<CB/5:(?,G)-06/-@+H06!<+<=C&1-?.#@5C#'>E'.6A1!<."F;629':H$2C3)C3)@1>;?:A
@r1986
NCCCACCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATNTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATG
+
#GB@.'7/89<?*952&D*E*2,53;3$2+?.92";+?D":H>6DB,E*9?,294+4B4H89<9/!%@@3?$7@F+3&>1.AF/1B&G),C,0<$F(+#5H&%G8#9/*DC;&B:G2D)@;28+>@D9919:A:#!016G&&0-)*A=<.&;>."A;0,&"ED8@1.1(#5552D8<$-;,?;:-+(80-*7'HC#+D2+-$36BA6EG@88)66!-
@r1987
AACCATTCCTGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCACACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACG
+
*()(+*$%%!)!+!#)%"$$#'!)(!*!'()"'"")((&$*"++$%%('''$*'*'('(&%((#%''+"&#)$))(%)(*%!&+*"#"&*)%"#&(+"!$*!')!*)!&%!+#""!+++
@r1988
TCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATANCAACAGCAGACTCAAAACATGACGAAAAGCCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTAAGAACAATTGAGTCATAGACCTTCCAGTATTCTCNTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATANACTCGCACAACGTTATTTCATACAACGTTTCTGCGGCATATAACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCCATATCAGGTGCA
+
5@=":#E6#BG'#;'8+7,=-#!DA=-C:4G;,(,G#;)60**C+A#,38DD92G5C$@->7<*@;"G=?-0+51C(=8:$0$>+:B-;#F,877A<E:CC2H51A2?A.:)$1),2A3&*D2,F$2C<2:4+?8<<3;,F%B/!;###@7=/-$#.B?;%1A'852;=!,55!4C&=&7=GC59F'?-H"EG)"&:<G%5==56"G&:.B)%8&%3'$67F23&&'+A49!".8C8B5%%9:66083??!;:>E4./5;!BA,B1,?F5>6@@4:@9H3,.H+@>#A%++3&A<$;$;E'='95.F)
@r1989
NCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTNTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCG
+
$4$!3>+>&'.#+:EAAF&.A17?C$G;&15'D"A0?&>,9/#661:6"'7=*<G@@/;%3/#:@H&-'8E/405!10C,5ADD;A@6+;54.51.><-$E-.+BF*E4)HCE72@?F=;BA'3C5#92*&:G8)$**H:=@*-@6.:!610HA2+:/B=C/649@&20<C<'6##DH%9,5'90C*A8:8D5.A;H<<3$EC$G-$6'D270%'C?%%+!E;!/'8&$&?2.AB!:E15F2@9351D)A4+-<C0(=5H34?C@)C#/%1D32#C3%!#"E0:&54'=*D'6)9G&4B,%.F.A80<*6)2B0"=+6<='>@'A#6B'=:"2H",)9>)D/G=6DC
@r1990
TGNTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCNCTGATATGCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGATAACCGT
+
'"!*+;)0@>.B%/3F43-'D+85*D!EE8CF;9)&@1E%G,&7G.C#35-8=(F=/<*4?#"):90=B"49"4*,!HF&*+00@76&@>H$E9&(?:>1+,'GBC&BB3&3:83!/C<2#>!373%C?$/2"H3<6!?"+?B9/+*%+'%0:>/#HCHB&/<>#&0=A=*H@'9H!H.$@,=",%8-/47;
@r1991
ACTACCGGATTTTGTAAAAACAGCCCTCCTCATANAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCT
+
2?=-@F4$/=%"@6$(/52.@$209HC&<6!'?'FHHG2(-55%(<*5?G0+&>:"8+%+@?C'!"$23H6C$+<#G-G*70EF>/=%H<:+)4C0727/B6-
@r1992
AGCGACGCACACACTCCCTCTGGNGTCACCGGGCATGGCGCGCATCTGCCTTTACGGG
+
6C&!!H4"(3A!9?:,>3&$.*85>1-<2%9;#>6@4?8*D3<*B<!$#02A>%$/:6
@r1993
TGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCNTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGNCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGNGTGCGGAAATCACGCTGATTTACAGCGGCAGCCNTAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGNTGTTTGCGCAGAAGGTGTCGGCATATACCGGC
+
,!;A,,?)&F3'7&5@:D&;1>BB6&<E%<:(1*6@D5HG!A=G>?07EE.=%7(?3$>$4B<D522*32&=13<15D-6C7*A;*8.$;E->B;/1BGCD.@2%416C9D<!G9D/%A('33:8C,A0*99.(1.%>0@?2=(>CD%8!=/2G$.0(40>@B#D(D*<'F*2H)7:C72/48"925;8<CB(,8G)8A#%39;#*A+B!/?3G62$DA>5F,@'?54E5'G="!;!D,59&#G%C77*:9B1"-6C/47%+;*67,G8&$8@!/)3;2"=9-!A:6;+D<%95=?*G)<1D',;@%5<G5C&9HD(HHHB3/(*!?
@r1994
ACCNGNCGNNNNGNTTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGNTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTATAGCAAGATTTTCCCTGTATTGCTGAAANGTGAT
+
&$(!'!#)#$%('$+'"!&!$#!&++$'&'+$%)!*#"("+&(&*'"(!&!+!(#'&$*")')))+&#!+%()#!()%)%!*(#(*(!'($*#''"*%(!#'#$)+$(##*"!'$*)'"$'("$"+(&#**(#(+#+$'#''"$+$(+'+&)&%"+&)+#*#()&&%!$'"
@r1995
GTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAGCGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGNC
+
"(;E($95-097)>1G&BH?3'B5"0="BC#"@=4G0#+B0:)CE=)$DB396*?2*/:)02C&02/3&)(@*?63?&,?EBB'E;'E#&34BF*,5BHF:B=7&+:-""4?"'/"1H9,+/&/>D!G*=BHFF3C-?4C@,0(G=H03+.6><F?@.HG$E!DG-!#7D$676:B96$<;0B!$-08
@r1996
AANNGAGTCAGCGNGCNCTGCNANTACGTCCGCCGGACAGG
+
%"$!'#$%$*#$"!*%"(!(($*$#("+#*%&%$#%%))'(
@r1997
ATCTGCAGCGTCCTGCAGCGGCGCAATATGCTCACTGGCNACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCNCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTNAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACNAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTAGGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGNAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTNCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGNACCAATACCNACNGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTNGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCNTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCCTGTTATTCGTCGATTTGGTGCCGTANTCGAANCTGCCTGTTGTTT
+
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
@r1998
GGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGNTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGNCGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTC
+
9%C0*(8)!6D9H0C87!)!,/A<&*!;#)5G(#9*:%F:$B;"A9(2B;FA!;DG>#$@+(AHD.F/6)3=@*G*@&(.(B&+/B+1)F/8AD)":#:(:A,!'B0#6H3GF><9.E-6D8C4(:82+><H%%.8);9?-1;B*$"?0,!2@6/3$!'0<)%(63&C3DC"(9;9
@r1999
ACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTNGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAG
+
H@+1$+E?!4;G),-99::!#@>4??EF"%+?4!9EH0*&);51*F3<>F&#A&=EA:6-">B'AA3?0:A?93)+05$E29<4<&")>DG+323.;75E!>F0(>&*G8C>@9$&@@335F+?AE,H'/FHC&$@F$0?A2)8'E:@G0A2A:0B1&(09#9*0'"D./FA$);(1?#C(7H#(.#5D7!=>5"8."$#.!4D21(<-3)+?%1(&)4@6D.>G,BH,-6':=B08A1'6C>E;9A74@H@F/A=B:=:&1*D(<,-,;/F#'..A+2!/7;=6:H=AF+8',08$)1!9!+*"@-G5.@?E%%H9'<,%0(/B-/6BHF1?8G=#4257E5(0-F.(+G0=($B9/DC;8
@r2000
CGGAGAGTCAGTTCGCGGTACTGCAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCANAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATNAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGC
+
C"-628@C8G'*B/H"04#FD,C$/3+*<.A.0)5;AF$'CC&98H34E0*/<9@1#/D>2A:?4*FH+@F?)+AAHH/G4FG<F>8*,#9H4+!7:4&G+4'9*-??-4-B<)DHH)/7:>>70@-/7/';5$95D.2D,BG2E4F*5':)%%98!-7,94!E$0@=3>27A/-$9F4#B#/(-:/$?$?0-<'05/=%9<H,4+@'3#90-C*'5G?4
@r2001
NCACCGTTGTTCGGCCGATGAAATGCATATNCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATNACATTCCTTT
+
));'5C@4A;5"7*C+&>=9+5%!++>'#3C3:E:#7'@%9<$?>9$FC?*C2%C9/FG(1*$A*3BG@++FB0<5?4;-F4?8E-B=&C/)5@C7@$D6%":1/.3D2
@r2002
TCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAA
+
+:#'$D&?;C2/4:AG"CB:7/5C0'+B4"*A&.C+8/.(",A'B28$<+$C008@8
@r2003
GATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCTGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGC
+
GF(.-4+88#C8"?,/5F+D$$!$(*4!<*GC.A=7)=:=-!7>'1*3#0F$0=5-0::)7$8B3+!E#2;&4'*:$%6.'.85!/?H&&(E%8F+9='<*D<-0D.73944;=;20)@)GD3?>F30)?C!>.5':$(,)<E'0EH$=#8E.-*<((7;C,*+&+G/0%",+/19A!0>HHF!@9C9+(G>9/:F+(#"A)?.>6C$7G*&F%7G%)#HHH"=!,=@D?1>F@.B:5;
@r2004
TATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTNAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCCTAACTCAACAGAAGATGCTTTGTGCATACAGCCNCTCATTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCNGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAANACAAAAC
+
47G;:B)>@>:6?:<'"B-44&@(E19:(047"D97C@6#?64'9A0GH1)1-D.C<C7@';0+H&B72*DA?>1+2#D.3?=;+06.!588&5E<=%4D7;D(!!-/D:=E8$854C%2!F*?>(0*(#/1AF0<:!H8HD8:;HDE2B#77(<G:.16++5%+46(&C01%8-4,!>=7A"%':#@<#43D72G+66H0/=0#@!.3$D(9E3HED@47#<5&F*'%8+@'>=@?.7=F9E**.D2B/6<(716*!==*829$'A4!29C?*G//6F"4F(802,C,;/;(9=D)@6<E.>@?81-:/EFC0.+7D,>-4-/++1%&4AC%-+/78F+:D6,1<F/46>!53&8G.H!4#27!@#>'87=-#5!8(.'(H:0(2<:H0,($14/>7$5,,H#$/,91A
@r2005
ATCCNNTCCGCNGTTCTTATNNNTNTGNNNCTCGCNANNNNNGNCNNNTGTNGCNNGTNNCNCNTNAGNGNNCCNNNNNTTNTNTCN
+
!##""$$$"##!$$$#$"$#"!!"$!$$"!"#$#!!!""!!!$!$!"""$###$$#$$!"!##!#$$$#$!!$$$"!!!"$!!!"#"
@r2006
CTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTG
+
G*&B('$H?C"/'6'<>G51#)F08:8,<7?>+"3"8*'91'>2;(+1E*E:'B*G/)3'G/;C5,C($D/:0*!,CH,BD-GEC&+&7D@HCADF13<=EH"4D#7>D&D@#$F1?F*:/6(@E*"?0'>G6@-38D?;!E,3@/-9,5=<(<FB/'$!@&")-H;D1C)7@:);:
@r2007
GNGTGGNAGCNTCCNNTNGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTNAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTNTGTATCGT
+
%#*'$#%**)!#*$!*("&+%&(++#&"&))"()%%*!+"*(($!"*&%#)'%'+&'"*$"(*!"&%!&)!$*(+$%*#"!!)(+'"'')*#'%'(!#&**(&$!'$++"!'&*"&#!%#*(!%")(")"%%*(*)%$+!+$**#"$($)+#(&++%!&(#'&$%$"(+&(("+$++%!#%")$#"#)*%""'*"*#!$+#)"*$(*+%+*!("('*
@r2008
ACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCNGCTCCGGCACATAGCAGTCCTAGGGACAGNGGCGTACAGTCATAGATGGTCGGTGNNAGGTGGTAGAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGC
+
DF))B=4623@0H"H!&534)9*E0%6D:%=A$,2@831((H!><&7?H=,0C@01&5)-%)9=''.//)GE$./!:9!4+&<$"./*%7*E(4..2?5H,%-="'7'/540@#=>&;3H>H-C/1E2$B/!B%8)10-#G>04*%/$F:*!=+/&2A>8"-8H3B"+%62+(7F8#?#-93<26B!;#:91&3@329(?E(@@%E"64;"(!,'A@F1'.8A%&D68,?$$A"&@"2*1F
@r2009
CGCCACCATTGAGAGTGNGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCTCGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTA
+
B7E;/C858'A6(C1D9;'<*'=(<!>15@/"560!:B31;!77H>--2>&$9"<0?''D"78,?86/0G!'GCE;.'9D"BC)%.22@19#)E"(;A3D$6!,4:+C!0A%#<5-%0H778,6BE,0#!6>6>"ED35.4'G44<(<*!D?-*'C(@*C4/+?&$D.4<)A,'6)B;H),%+?/"-?<"H/!012G'(@&<F2'/4$52&64B9A+73B:.B<"/<G'3;"1A3F?*.58"16'$,#/2"#FCB?##<;!8E'=64G)9/>33=/9<C#23.3@17B>).08<1+@1:F'EF",/7@+GD:(8FF#",.2G=1HG++$(,(>8C1'#,-,?BB<68&
@r2010
GTGNANNTTAAATAAAAACATTAAGTTCTGACGAANAAGAGCGGANACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGANTCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGNCAGNCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCGTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGNACACAGAATATGAAGCCCGCTGCCAGAAAAANGCATTCCGTGGTTGTCATACCTGGTTT
+
!!%!%$!$)#+&$)+$%'&)&"+%***#$)!'*)$&($'*!%#&"&*+&(#&")(#)!$!#+#%$(#%#!'+)+$!$#*!+"$#&!"(%*()"&(&(!!)&'#!+'!')#!'$&'**"'(''*+#&(#&$"!+&+#'&%&!%$$$"(($'$"#'&%#$+!!!!+"++#'(&%"(%&+(&&))$&$$*")!"#($*""#"(&)&!"*#!$($%"")$$)*)%*%#$%&$'$#!&#%#$*&*!$!'("$("!$$+%))"*&#$*!%&'(!'(&&)"(#*&#"'*#+*#%!#*((&%$'%&'$%'*(%#++&'"+!)(&)#""!%)!$$$%$"'%"%+%($&'%($+"+&++'#%&$&%)&*(#*(*&"#+"+*$(+'*))&#%'!&!+#'*%*''$(&!$%%!+&)%)#)+)&'&**'!$&'+%&!!))!*$')%")%''(*"$$)*))''("+!"%#&+&"'!#%(+(#"$#+''!"*&"!""!(++!&!$!'("%!*"(+")!(%#+%''"+'!%+$&(+%*&!$%$&)#'(!&'%))"%!&($$'%*(+%+)"*#%%!++")""&%
@r2011
GGTGATGGCATACGTGCCGTNGTCGTTCTCACGGATACTCAC
+
%G7!7E<;/>1(C5E1093?=<=@E-F"5A0+?E<2?H?#&G
@r2012
CGAGTAGATGCAATTATGGTTTCTCCGCCAANAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTG
+
A2/A6</@G+BH*!B<-:+%6&2>?;:?8DH3141&/")G0;+)+1&B7."DB5#"D*(+(01*8A/!E#,/.:A"D2>AG;<1F8C9'H'*!4!9;55#A%4#AD1,4%C2.D)4,"AB20!);2/
@r2013
GNCNTAATAACAGAGTTAAAGCNGTNCNNNATTNAGAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAANATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATANGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCANTGGATGGTAGCGAAGNANTAAGANTTACCGATATCGATACATCAGNAATATTTGATTCAGATG
+
"""$(#!%!('%#'$!&*')%"'&%")*#)##'!)!&+$*)(&''))"('*$#"+)#%!'!%((+!+*(%!*##'($!#+"!)&%*$+*#)&&**"+$'&+#*!"(*((#"*'(")+'*%*$'&"#++((((!'%$&)'+)*)%(+%$!)$')$)')##+%("#*!*"*($#$"%'$&("(#+"(&!%$$!$!+&&&)#$+%'%"*%"!$%%%&(#$*&$"*(%($%!)!#&(+(+$""+(''#($"$$())*%')%!!!!'$!&"
@r2014
ACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCA
+
C-.:*C'H$*5CC4E,$8(=)D+6-/=2??=<5&1//4G9-8C8EBA";;B;+:+0<9C#3(98<5F,';9E&8&0"F0B+>"67!,@,'.#1AA8.&9:.'+@5E=1$6C*BG*9GD1,F=#6,/60GE9<>5)C814.(.6GCA=%"%:+F;>%(1C=;#1
@r2015
GGNGNTANNAANNTCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGNGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATNACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGNTTACTCCGATCACCCTCGCAAACTTGTCACGCTAAAC
+
#!!%$%$"!%&#"%+*'!''!"(''#$(%(%+#())#("&%!%)$&)$&$)"'(%'*!*$%(#%"'$!"))$#$'*)(((+&'$$"$%$"#)$$'((((%+%#'!#($%'%(%$#&*"#&)!((&*'*($+!)!))#$&&)$(+%%)""!#$"(#"&&$()"("*(!$%%#$+)+%$*$$*'&%%$&)'*%&$
@r2016
TGTGNTAATAGGCCAGTCAACAAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACNGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGANTGGNNCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACNTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACACGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACACGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGNTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAANTCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATT
+
A:G=>5,:$-D1#:<G#?:E(&8$6G-87):<62,(9E?-!%+4F;H?FD7'!)'D@'E"0EH,=.A%"/E6,<;%*(.,A@2;A4<1(4#G-)>C*&.&%?DD#/0G,!.<0!"39--#5;.+FDD+CC*0+/#A07/=5).F#E@)%(A.3+27AF4=9A><!10)=&CB,H8(&4E</'%@H)B&2B*F":73.38!>-#+4*D82-DC<G#-'*="C4B./C%,>4G&C687!&/,@*!'-1<HE5"G>;;('0;GC8H/C#$HC6877+G0B4?E*$F&!*+F1-)(D<35.7@.$+%=9"85BA$%3@00HF%/=B:C4@/@')!'5*&6A?B+'?E(>@EE!B,$G3%G-(1*!GA&*66A$.7A#EAC?7B$:*)?10G$5'0+<-,EA0.6-1BC7#):A:21.804BDG3.<B:/&,=0C(?0*E$,D%"=<<*;44-,+=:E=A((&==+931+8?H5C+(-.B4$GG9G8AA,/#&'/*#=3/B+;/GF@E@G7<7%;+:<DH:09F):%5?%?9%.?.@2"A7.3:C(/<G.1CB.(!&0*A#'A((.#46:C@"-@08C:5'F,C#A93(=?1@:G7>8(>;598?*"81<.#.FD?>59@"97H-%>#?.G@98)-%'EC"57!=C$*)D@=4=@&%,?>,0?/<6-%!;9GB.:.1)H+@E0)>/&;-,=,.@&&&$=5@02/5=$C#C3*E!6A18F#@0@4(9&#H,;E<(*D39H/972'8+7F(E"EEF8C"D?9?/(>1+&:4>'&#"8::3<2$/5&*?-7=/'.@@.C<=#*):@(+'&3.>E7.()8A//<F<H.D@=:/F:)7!EC@;!;!B$8*?G$"H.C>33!
@r2017
NATGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTC
+
"!+**"(&$'*+")"'%++'&+"("(+#%&(!%&''*)"!+)!*(!*$%+$%''*((&!*"+))"'#*")$"$##)*!%#!""$(%&)%!(+)*!*(#**')$"'%%'!#*(#$+%%+%(!$#)%#*!*"&#"$#**!+'%*&"*##!'#'*()$'*(+$%'("+&$*'%)""*'!%'+*"*#(*$""!&!"!(##%"%**+&*"*&#*)%)"$'%&)"'((&&)&)'&('*#'()+#)%*''#''&&!$"
@r2018
ATCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTNATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTNATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAANTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCC
+
#4"&01%!G0<5#"4F"8FH=4>/55,;B;)5F49$..34F>:"-.<BC;$HB2E;6C@C%*.:;0)#2@,F<@DHB@'!3/328'%3"",8H.$-@'*A!%H?:>C"2=#?BH(85";;<B0D.D</=;.F@(6=B-321A<1DF&1'A2.+99AG#D80(:4G4/C&B?C-E<,<1.)H$,7'&94&=2G-E5.$?5H,6)60.B6H%!-%&!)6"."(..HD1G8=2;%H:='01:B=(7"0/6:'"'&54H&"C,B(A30"8"&$-4"A)G<:F72H#?7A%-02)35)C:H&-%;$,;3F5+DG,-*8HE,:HEG9+BB,B5:&4=G30E..,;C*9@.")(=**H&H?8%+3(CC>#6>#>C>.1+D%'5A%:/8%3"=!-61D*G!!>61:0/:1,>9:?5(E":D0;?.E7-!2!E)@5!$;:H*+'H4C!#4C/)(103.04,#H1<>771'!":E/!DH8H&G:F,,B6;2$+G?E37
@r2019
ATCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGNCGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGC
+
#E4E5+C-0C91"F9;2E(/25-;FB8*D!-);:0B-*9C5*,DBHED=@6"5>7G%D-!8<85D>0@8>(<C#A%#!&+84<0,!&4!E:%C<?0@77)&9(A/0E6D15E0/.8
@r2020
AGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACCGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTNCACCATTCAGCTGAAAGCCAGACTTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCNTGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATNGCACGCC
+
D">4E=?)$&DE&%*3F,')!/C6>E!5C.,?2;,8("F#"7278F4$>)/!#/@>!"=!;0+A$:8;+>)90=B&?C""5F2C6<$>>4FG)62&H:7(>6E+G?&41>533%F-28#;:6&7-A@"8@8A$C%)=)?-G227/??&:E21C@B-*3(AE:2$24=D*7+680%4!D.0<@FE!57+1:F4-C168>/@@HA3F<31,6DD+=20+09:(G$F#503D+1>*B,$8F/1,/$$=C%@,+BC4F;H$)?">(B,/&DA.?<6":D!0=*.'"!H/4E%="4&9&39,9,G+FF6(?16AE?H+7,8G$-A8H!3@4D=&!9=-0
@r2021
CGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGAAGATCACTATGCCGGTATCAGCAC
+
09*9A0=1.C+<)70?E1)5FE2=7D*.6#$D=8/FB4!!3D,04.A?!+4-(9$D*99H:A&69EC@3D@"
@r2022
GNCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGNGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAANCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCCTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACNAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGTGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGACATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGC
+
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
@r2023
GCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTNTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCANCACCGAGGCCANATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGANTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCANATCCCTCCGGC
+
-/:;(-6G<HF</FBF7.(+*6GD*/FF589#%("DA-<?*==+4E8:DB##H1#1E1C<-502;)1G,2.E./DA/+3E!(4'!:?9?+:D7#<,;,(0<&1"80F,'/1:)?$42D-0*C(#7A,"/@A97+%89*(+F*B;%'<#<#6#4;?$"0HFA8:1:H@>".:H.5+(8+=A14GGE7C;+1?+?@D7*C=)H>?#0D5?3*B7741&65&#9,!=*A!H)18=3)#;FF:52#,+/77%@!=0!4"$?C/4E;(.6EF8%2AE0G?91H>;G69C:8DE)E)"9+7:-AH56@2E*.!:3G<=F7,F5?160+F(C:/934?/0+!8$96?7/?'A85.2,5%+-@5.5!3"9#B+'(#B57H?FBC=$-B@*=H>G:H;=:"5$3F&D?%'1A0$H=</G&$<'!"-420@,G+H65
@r2024
CGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCT
+
&CHD?<'D628&>F<+-@@0-=*3"4/C,#);B9%+=;&?=)..&<D3!>6A$(/D@1?!B337=("C*3G191B6''B7C5(#:*B=:"-/6+-6%47##2C&>1)7BD5BB139D5+!:<0$$D?9+8&A/'C.G0=2(43/>2/=%C027B7;5)=<*,D!#32H3F%$!3&H5=1
@r2025
NGNGANNNCNCNNCNNGGTCNNNGNANTTGGTNNTCNAGCGTNCGGNNAAANNNCNCNCNGNNNNGANNAANGNGANNCGNCGCTNNNTGNTNTTAACNACNCNANCNACCGNANANNATGNGNCANNTNNNNNAGGNAGAAANGNNCNGCGATNNNNNATNCANNCNCAGGANCTNGNNNNNNNNCNNNNNGGAGTAGNNACCNAAGGT
+
""!##!"$$!#$!$""##"!!!"$#""$$$##!##$"""#$#!"#$!#$$!!#$$#!"#$$!!"$#""!$#"$""$#$#""!#"##!$""!$$$#"#$#$#!#"$#""$#!$#!!$#!$"""$!#!##!##"#!##!!"$"!#$#"##!$"#!!"!!$""$""!$"!!#"##!#$"$$!$$#!"!!!!!!!"""$#"!!"!#!$"!#$#$
@r2026
TGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCNGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCNACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATNCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCNGTGCTGCCGGTGTCCGGCACGCTGGTCAGCNGGACGCGGGCGCTGCAGCCGT
+
7;F$97?,971B=(+!6:B:)''=2&;*""H=G*778!+52HF&7F(D?,:B)?5!(GAA$!9D1!228=):H)07%.9"9(=6:'/9+"@!(C1(50430%"==<4)3%:==("B'0&@2B/--'?H+$#E)=!71A<*(-<''D+$216'$20#,G0$*+(:,!43?-81BG3.5=B23D5D19(F>3.#%?1;6E&6>#77&@BC::):%+FGD4$1"'<"3+@$:@:)HC((&#5D&?0"/%3:(26>26=?,4;1!$8@54$F$H@/11-8AB*-&5!!%"?&504+25.>H83-+<D"00C*?;>2#"G=65=C+./71>:,5%E,0".ED2>):%4>6B(-<-"@)0D$
@r2027
GCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAAT
+
)#+#)+)'%&"$)'%'""!)!*%'$*%#'$"#&&#'&#!*(#!!$#&""
@r2028
ANGGGCGATTCAGCGCAGTCAAATGCCCCCGCNACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATNACCTGATAACTGCGNGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTATAGGCCATGCNGGNAATANGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCTCAGGCGGGCGGTTTAAGACCGGNTGCNCGGCGCTCCATCGTTTCNCGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCNTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTGCTGAACTTCTTTCAGNCCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGNGGGCTT
+
$"%+%#&+*&#*'(+%)$'""'$**)!+*(#(!))(%$+)$"&#&'"#*)%)$%"(+!'$"*()'(("$($#)*#+)%("*!"%!++*'%$*!)$+"$+'&("((&%!)&'!+"##(+$('$'*(''#%#+"+(+)"('+(&*%'"+#('$+('+*)(!('&('#)+'%"&'"''&'!+%#''*%$*("$"$$&'%!&%#%")%*&*!'*'"%!)$$*)'!("%!'#)$'#*%!#+%!')'&"%'$)!')+%*"'(!"%#(!%"$&)%"$($+&)%%%%%)"(''*)+$"*'#((&*$*)&+"!'&(%&+!!$#&%+''"++%&'*&%+!&(&!+$+!')&&(%$)'($)($(*"%%+"(!%%)+(*&*'%"&&+&()#"*&*$"(%')%%*!()'%*$'#!'*)+!+''((++'$(&"#$!)&""!!'('")$"#*'++!*&$(&"%$*))%"'$#*(*)#&%&##)#'("'()*#)&!$''##+#+&&$$(+$(!"#*)")+$"+"$'#!')!$%(!($'%'+%"$+&$+#$)'')*"$+(!)$&&+)##*#('*$'(#$%)*'*'*%'%!"&%&&#$%$'!*#&(%))$&!($##""'()&(%(+*)'$"&#$$%+("+()!'+($""$$'++$#+*&#$)!$!**)&!*(!((+&!(&"#*#!$&'(&$+#)!*#)**)+!%#'#'+++*(!!%)+**$(&&&&#'(&(#&!
@r2029
NCTTACCATGTATCTCGTGCGGAACGCTCACGTGTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCNATTTAATGAACGCAANATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGCCGAAATCGAATGAAACCATAACCGCCATCGCTGGACTATCGAAGACTGCAAGGCGATCAAGGCANAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAA
+
#:EDE,5,C:E66!CE;0&2-01>&":/(8.9F6GA>**D4ED=E8,+B&?(F(A<>,CC3!0/$D#?G>#H&,9$2-9$4?</15@)'18<+/8G'!$9,8@&191G.#5%=B%A3D1<#"3G3"7G=&<"G=>C09>=$'56,7A@;HBC"?;/8D=B2!+5C%!B%D)(A-:18C:!C(@()7,,:DGA-2:D;BH'35$(%D8H6-"(116&/E179)(H)B%8"!/H7(5/D#(>87'D*(?,>B.?(7*,9?%7E$+(-G*#639.>EG>:%572D0@$*F;;0.==9G-3=/>$::1+#=#D5*(.:G+:'0**E3H??:8H!%4?
@r2030
GCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCT
+
?7%D@E7,(7?;D8C/>-7,25;<ED8<4=)05;15@H-D"&@=E%G(5
@r2031
TGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTTCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGNTNACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCTTTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTTTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGC
+
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
@r2032
GTGGCCTTTTGAAGAGGATCAGAAATGGGAAGCAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAANGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAG
+
+")#'!$(%!$'$""#%**(+$#+"'$#"#$%%++)#"+')&(!*#'"#!(&+%$*%"$)!*'*&'$("$&****$*+!!$#")%!*%&"+%)%*$$&++'&&(%('+*%+%(!'%((((&!##($$$)#%!#(++))*!"!&(!&("#)*$*!')#'+#"!*%+$'*"$&"#'
@r2033
ATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATACATGATTAAACCCAATATTACANAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTNACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTATCCAATATTCGAATTGAAGAACTGGAAGAACACCAAGCCGCCTGATGGC
+
;;/#%91(F:DBD"785AA=G()AC0$G>.C2;:7D&;(;(/"-;0.*900079:<G4+D9'8/7)/+3/E*1BA846G7FA*D9;3>+.+<EB)5=.:>+#8!:HH/<'EG*"3;2G<)79E(E0DC3-&=<BEE*19CC@+'FC.;F<*<)37)6=7,"*7"E:381:AD81+9(#,'';76C'/3)H:&,;D,;./B"<(;D<;6'BA1F7>73B0-2*;F)%BA3+1.#9*:4E1,-5,5'A271!FC7;7.8G+4@78949,#H#$(E>>!,:4&"+=";2&*#+"23"',6!059&CC:D*>5<)2*A)E,FB(9<A%)C"A@?D.$@#E&F:6$#3G2E@!/<D=.7"
@r2034
GTCAGCTCAGGAAGCGTCCTCCGGCGCANAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAG
+
<.>0'628A6(;(7=31@7&2%%"0%,'2%2.9DAE11=6!$*7::!:HDB:)@5=.9$/,#F646
@r2035
TTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATAGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCANTGCCCGTCAGGCTAATTNTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTC
+
*G.836*E#;A=H=*'=HHDA341/)HEG(#<G'4@(5&CE#D2BC;7H9C;(CC.509C5<D77<7<'9BA@"E9FG#:.%&%=8-0/.4(!>&H&2',</6D;/+$+5&.91:D;3+0%2BGF%+<G$*;9CG>>F4*%4:8-!)7:1,8G4=7@B
@r2036
CTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTACAGTATATCACTTTTCATTCTAGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCCTAATGACTATATCCAATGAGTCAAAAAGCTCC
+
<#$CD0)"C6H=,2=91/+HD&!?F>0('?@H+B:(-%>!:A0;&?(>D,1*4&A5%1!'/%B),:,H:@D%<$+&-3%9@),?D,F2*DB;5$/(>8%9?!;2F#+0@B3-/7>1*6.,(6:+?5H0?.D=A$C+"84E65:?@+1.H(+%@+&.3>GG#@>>"H9-573*"'0'5*#"7@6%<55E2)!,2@>609"''!=F)%!738'1.0/6"GG@#$,51D%)'%DF55A$!.EG>D-A8+48/+75"C-1@+:"/$:+>7EE'5/78E(CA?<+E4+@=$H.2.4AH+/3-%5CA66=>1"/>A@-6C%3<;3&CC*&%D!!,6$C-$@!B29)H2F#CH9
@r2037
ATAATAATNTTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTACTTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTNGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATTACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTNAATNAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGT
+
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
@r2038
CGCTTACGGCTGGAGGTGTCCAGCATCNGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTNAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCTGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTT
+
"*/99)4?/2#8!89;;4188,3&>%:*(8%!"$))8<<?!;98%A,*/F6H"?D8#(A69!/-@18/4%;!:A3A,F*)445$=B'%,G/%C=!GD'E8B'559?3@<1$>>80>%!5"31C47=118DAF'8DG:#%)'C36>661;'C917G2?/<4A;A%D)E-*8-"0#,'6;-B.C#9#1G8&D.:+&&&<7@-/;'E3D<>6A&1<?C47B(+F<CG0"&)46-3E';*,32D5+0)G61E16#3$=E60(=)=H2&:#9;/+G*B@74@1;AGB@2?'3:F)4/2)<E9HH*3,AFC22%82%?.=F%-44-+"H53.-F-/"H<1?@7/41B55H94
@r2039
CAAAGACGATGTAAAAACGATGAATGCCGGGAATGATTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCACCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACNCGAAAAAGCGGAAAAANCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTNACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATGNATCNCGTGCGGAACGCTCACGTCTGCTCAGTGNGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCANAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGTGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGNGCAAGNCNATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCNAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAANACGGGAAAATGTCCGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCNGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCNTGGAAACGTTAATCACTGGCTGCTTAATGGCGGNGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTNTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAACTATGTTATCTGCCACGCCGATTAACCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATNATCAGCAGGTAATCTGGAACCGCGAANG
+
'"+#+%)$$&)$*%$((&)*)(#('*(**$((!)*)$$$+#($)"')%"(+$!&*+()***+&++%#*#!""(&'$"%#'!%&'!!(##!)+&#$#++&*('!&()*''(&"'))$($&)&#'+!#**&()"''+$*(*(+&'$+$)#"+"#"'*+%#)%*''))'')%&&"+)+%*#%*+$+%*!+((&+&++!$**&)(*(&)*$$%&$#(#$!)('#")#"%(%%)**)&'"##)"*(''$&'%%$#!'!)'&#'+)$$(**!"+*+&%#'"!')*"+()"*&(!'(!&&+"#)&*(+"%*')&)&!(#"$!)")$&!!$!**'!'%!(#)*#!!")#'#)"*+#%"(&$#)*!"$%"'()+"*&!*""!(#$'""!"!*'"!!'%#'%$&()##"("!(&+(*")("!+))()*#%#*+*""%%($'!%(%#)(!))*'"#+#*)$+*)!))+"%(!(!(('*'+!!##*+'**!""*(""'(#(($(&$#('(("#%$%")+!(''')(""((%$%%'%(*%'(#"%'#'#('%!*(&*'*#++*+$#*$$#()+*)!%%*&#*&"*(&)+'$%!+")"***#)#*$)%&(!!*&!$%%!#(%(+'*(+&+'$!#&#'%&()'*%+!*"()&'"+'''$!"%*#%#&%'!(*+'*('"!+$('"#%)')%$%(&%$'+"#'"("(%(*(#!)%%##&"*+*!&*+%('&&&')%("$"*"!#++!&!($)#"!)#'#+%%*#(++)")%&('%!$$+%&*#&"*(#")$**'*$+*$$$$$*("'"))'&$('$+''#%%%#'$$+'%)')%(%"%#($+(#&(++)()%$'*(()"!%'*(*"%"%#+$"('#&#'(()+#!$&(&$'$$&#&%!"%"""(&(')#")%$$%$!("#+*+(")#''$!&'&+!'#!$*"'$%!*""(%+)!!#&'!%+%&*!*%#&!)'*%&$%$(*"!*($)##")"")$%!!(&&(!(%**)'''+%!!"+'$+"$'%+"%(##+(%%%&#%(*"(((&*("%!*(($*#)")%*(("#*((#+!$)!&)$&%"*)(+!(#(#!!'&#)&)"!)(#)#''#$('*))*((#&%+(*!)&+&"+$*"%$)+)%#**+%"&"&)+$+&"!#('*!("("!("%!')#$!*(%)+!#)$&+)"&&++%)'&!*)"%##%)!('*%'!)'""&+#+####%'*#'#"&"*''+'#%$&&$!#'$')!"#*)%)+#$('%&*!(#)'("+!++%$$+(()+)
@r2040
TNCTGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACTGGAAAACGTAAAACCTTCGTNAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAACGAGCATTATTCAGCGCCNGTTCCTGACCGTGTGGCTTACCTGACCGCCAGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAANCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGCCGCTGCTCCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGNATGGTGCAGAAAAGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAANGCTCGAAAAAAN
+
#"(%+!)$#)+!$)*!'*+($($"'*#%#+'!+!(*)*'"+'"#)"'&)$#&"%)#'%$#!("'%&&+(#(#"%"')(!#+"(*&+'"!(+!"*)'(*!#%)+)+("&'('"+!()*#+(#&$'*'&!$!$"((!&%%%"*$''')$*"!#$+)*)+*!*"(&*'"#*%#"%$($##!$&!)+#++('!")#$"!#%%+)#$'#'(*!)$'#)$'*$*%(#"$&&'*')(&*"*!!#'*%#*%+'**(+*#%$"(%%!"+&"'+'&!$!*))$*&!"(*##%*##!(#+!$##!%++"*'#!))%+*$%&%%)%*))*'*&)"#$+&&(*%&""*($!%')&!)$&+"+*$#*'"*"('&((!'+#'($+'))$&%&*+"+%#"'!("&#"')*)*+%"(+"#&%&)!$+#++%'#'#*'&+"&'")!+*)&*'%&'"#!%*#+$*%$%(("+*
@r2041
GTGCAGGCAGAATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTANGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCT
+
3499=HC72(E?72.,!+'+,80C6B)+">2&"/@$%*,?3G%!3)&D-32#.'E(FG-#"'%;<D*;-@&F(,-3",94#%FHE,$HCC4-%G.<+>EDE<#'E#&;=&F->'(F/54*AC13;*4H-.;F3;&1#&GF1%=E3G5G2<$:!EFD92+.?="3"DA)35)-D,=#?$C7;)&F6=-DAF*/"3#CE'C17*2-FG8G013.*;4(6-)>"-)26>?G.C$)?&7>C:<=7174>1<@$0/((01:D89"":&0A+"6!2C&$+.C:5==!9'"'#*D&(A-!.!:*HFA4/1#$:";5@2;,G<(;#%"@*.;%:?0DF#2FAE=19D>'$5G7&;?E1E)&5H&A<@29:G.6A(;=.2?$5,;+?H>)9*H
@r2042
TGCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCACACAGAGAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATAGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCAT
+
'2!F$H#FCGH1-,==8FC5E8)!8+!F=0C=*618B#,H#1)#1;0,7'E<0F!F!C)*F&H3+4:*G#D;<"643"'"8+46&B#'<(.'B-%)3G=)6F=DCC,E(B82<;H<;H5%6$>#(@816=03#A@+"<E$5439$<3":./7&<=+9FA3"1!)>7,3$4*+.3(#4,=+55F$/+.*)-67/.+1=A)H'C3*93=@)H/+B&7-0)%0?2D/75401C782A&53*+./$F$3C?B5D#E&888;7E'DF*,>5E81(7+F+"E-5/G217/.6A.D?2$&/%=@6))D7$3F5*.(E0-$0:$=+)93'-&2%%&;G9E@>
@r2043
CATGTTNGNCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATNAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATNTTCNCTCAGCAACCCCGGTAT
+
$#&$$)#*#(+!$'"!"$&%!))(%!+%(("$"%*++(%$$+)"&*!((((%'%&)(''$$"!%&("'+#*%%!+')(!%('#"++!))$*$+!"#$$*+&)%$*'*+"!%&(++#+%((!!)%$'!')'%((&$#!)*)+&&#"*!#!%**%'(''$!!*%)+&&'&!))(+%"'*%'")&"($*'"++##!!%#%%#
@r2044
CCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGGAGTTCCGGCTCGGTGGTTTNGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGANGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAAT
+
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
@r2045
CTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGTTTGTCACCCAGGAANGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGA
+
$.(BF$4'7*=8$A?:EG7"60",.'05D;$=)-=-!%A>(>?!7D'H,+)75ECE5>%6;A@B%4?-7D*G.&GH<A+&#+B,9CC*9@%+9G:G(B.,)G=:A5*'5A%3'$):@D@:C8H(B*:.!B.<BE7;EH:C)##?<$3072F,=H29=78:6F>HB+;#+
@r2046
CAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCTGCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCNGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTNGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATAC
+
23+;<$*$B3?5?<;;E,+7%3C26:(5'*./C23EAC582+%&%A<8&5>F256!A1.7":#>.$G41363/51,:>%A!8,F3?7/@A9?D;4B-)!E=H5E,-5>H.H*6:0-(++>>-3FC''#@@+#9:821==5846&36'2D:/:.7#&$!@A92B2>B2E-3;@8B?45B:0)4F<EC0B!-H1-D<#(",5)-B6'7#1;*;'&!GD2.D1*A--/51&0%>)%(,D35+.H!,6-#$78)C1,H#$+F%144H29A&8D0A(6%A-)0#94E;,C4/%B3F'E5$F-%(C#2.'?$2G@9+/@!3;+"!>/H;H7F2D@(/6#"3D"A.C<G@E&'@)"D
@r2047
CGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGA
+
/D$9@3/@9"(>=.521+:08#34!+#)$A4#?.;E7/2;%4C;."(:**H*-?-A3D>)-23C=EB'66/DD6!:'0?6!F&#GB)DEABCE0(<;;4C7E)B+@:9,))14
@r2048
AACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGANGGCAGATCATATGCTGGTCCTGTCCAGNGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGT
+
;6GC(;8GA$6B*;@=:9'+,:7(A->BGF&@!.F)2A!H32*3)20"/&D8>%.*1!4/#36$;/?D?=#'--9(%DA;#D;CE#EGD&?B941"6463"56&7D4;E?2"?A=*!-3;D(FC%71+')8,>E&G/F2>49C&'3"3EC.A'<D6F4;0&.'0"'/5G5;=/">'23F3CA?4E#$1+F>6;%0F1A9H5'=-0DD.#82>
@r2049
GACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACNCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCC
+
$D0/+!A;'>+D@C5>+"-/$>=BB7&%1FC?=!4&.%#"2HD?*D%5/*<@"(.H67-1@,=.(!#2)++,G<A(81G&;$A95E;(':"1"3"G=>=#"B;1"8$@5%4$@>(H./'"4,D50$F5C;D%%4);2<84.,?+A9.26<$$
@r2050
NNATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTNTGACTCAATTGTTCATAGTGTTTANATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCNGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATATCGGTTTATTGGAGTTGATGCTTGCTTTTCTGAGCCATAGCTCTGATNTCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGGATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATATTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTNTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATT
+
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
@r2051
ACTANGTNANTTCCNCATTAAGATGCAAAACGATAANGTGCGATCAGTAATTCAAAACCTTACAGAAGNGCAAGCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGNATGGAAAGCATATATTATTCCCTATTGAGGNTATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTNTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGNTTTCGGTT
+
$#")""*%*$'&##&++&)++#+""%$$(+%#"'#(*+$$$)()$(%%)+)#!+#!+&+''&()#!#"*&')&(""&+!(*(%&#"!"'$%"&*+#(&'!'&!!!#('!*%*%&"$%(++!%'"%+'$('#')+"")%'%&#+++"(#*!#&*#!""(*(%$&'*""("#+'+'%#$%#%$%+"&'+&&#%%%'#%#('$*""%!$%('#!+!"'#'+$"'%!)&)$)!"$(+$$+$(%'#$*%&!""%+%'$"+'&$%%*+)*"""))')*%'()#("(")'++#'(*($'&#%&*$((#"!$*("'#!%$#%+%#$'&#"!%")"$!)#+)!*+)"""&"'!#)'*"+!!$)#)%(*$#%&"'&*+%%)$&+&(%(*$**$#"%"&&"()$(!!(#%*!!!$!+)!")!&*&##)*)$'"&!#$"(%#*!#+)(''*'("&$$'%#%#')$&!)*")*)+!&%&)'#'#&#$()'#"**!+&(#*#)##&*'!%#%
@r2052
CCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTNCAGCAC
+
BA;1>9821E&A',,6903H6:%"@C)HB(%+-40C.B*2E=17B
@r2053
TANNCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACNCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGC
+
&(#"+$'+!++&()(#!#"%$!(+&$'$#($'&'!%&*#!#)&&%)!&((&&%("$()+"*"#!("%()+(+%**++(#&#&%&!(!#!*"'$+!")'$++)++!!#"+$&!%)'*&("$()')+%!)'$*$+!$'+'$)**#)#&+%'+"#)*''!)*!"("&+)"!!$#!%*+#%("'%+!%)"
@r2054
ACCTTCGTGAAAGCGGGTGGCANGAGGTCGCGCTAACAACCTCCTGCCGNTTTGCCCGTGCATATCGGTCACGAACNAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCAATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGNGGCAATCCTTGCGTTTGCAATGGCGT
+
;CD&%'5*(;@C-8/GAFD0G53.FG/&85%74'AC@F&@AB%7)4.6'D74%)F=@2C6103B-4-D=DDE6>B2B:9?BA43):(E@109:')A"55!"D?$>51;>HE;B4+B007(%17B3?52?<GA#='*$$!A+-";3!/:>)"&0:%/*>?#-:5H1EAD?H#3?B&=95)F:2EEG@7&!>$*4:=<3?=+B"#98"9($).:..!E&$#&7$%!.H:</./C3$7)1A9:F/G475GFB<>#82'H'&0:*'8%
@r2055
CAGAGTGGATGTTTGACATGGTCAAGTCTATCGCACCATCAGCGAGAAAACCGAATTTTGCTGGGTGGGCTAACGATA
+
;$<@->.34#9/:F'E&;@@/D/%+)3+1"@0FE"1="'#%4,*70F6':#863CED)/B7!GG624A0$$<+89(D@
@r2056
CAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATAGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCNGTGCTCACACACGTGAACTTCCAGCACATGCAGCTACTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTANCTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATT
+
:)E5A+?(;47$/;01<@:)&=G2A;77AC">-FGB@:AH;!?.1=%>892"FB=!E<<26$F;?B&+%%%<BA2/>:<:B&H.-/@2#E!*(<H@/G&E9-!)F13($4A!%F'>+(3F++71-<E?/@.$@,0/=%<274!3B8.#576"21!902A@?-1FE0/.$$6>,*(A0=95H"!F*/2>D2)0"56:$?F68*/##@&?7G#4$9A+&>.+0-%&6:;2"!B&/;F9)H25F91.3GCD:1!+-#@%B;@D<1)83>$9#6+12*>F7!.#<:*9.5;*<G!*E40":).9<-
@r2057
GAGATAAAACACGCTGNAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTNGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCANCAAAAGCAGCAAGTTCATCA
+
D7,7!G!B*0**;9&D%:(&&4<B+>$2B5/GB==5((D.:3+"F!;+'A.?*!E4%->H=(&,3!*+3:8'85&$B/BG@7/A93+8C@20F+D5+.1:'+&3=E@-"46A"/-9::D@#1,5!4!<#!B3#(,6,7/48E(A1.:3@%<'G=(35'(/D%?$'')6.)(7(A14#&.97BB3<'A9BB@8.2$3$@-8G%C2$=$*+<@$5B'=?7'84/A,0>H0?1BF,213*#6.7.0%:?&2?&.D+E*:%/B;;BC6B%=$05C'7DC.71E210=4+!B74
@r2058
ATGGTAATAAAGCGATGAAACATNCTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGNTGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAG
+
+D,6D@8'@%E*-;+;&"-4-3GF"@@(H,/7C@0C.F<=9'!CG27<..0$.5',.,9C@)':,4B1A(=C$0H!C!)97%578(B=<!+;EF%"?0.E+?3D0A..!176F>'649"30#+%@7-H/F-04*697,?;=&F'/7+G#$4,6-C30317@91G,5H
@r2059
NGNCNNGCCCAANNNGNTAAGCNNCACNAGATTTNGGTNNNCAGGNNATNNGNGNATTCTTATNNTNGTNCNCGGNNANNNNTAGTNNCCNTCNNGTACNCAGNGANANGGNGCGCCNTNGTNNTNCNCGACGTNCCNATNNNNNNAGATCNCNCCCANTCACANTNGGTNGNNGNNGNGANNANGNANAANNANGCGGNTGGANGCNNANACGANNNNNTGNNNNGATCGATAANAGNNTCNGNANGGNNCATNACTCTNNCNAAAGNGGCATCNNGTNNGNNTGAANAGNNGAAGTNGNNNNNGANNACNNNCANAGNCNNTGNNNATTNCTNNCANNAAAANTGNAANTNNANGGNGNNATNCNANANCAATTGTATNNAAANANNNGANGAGTANCNNGNNNGGCATNGNCGTNCCNNNGGTCANCNGATCNNTTGNCCANNNGTTNTNNNACCTGTGNNTNNNGTACNGNNNGCNCNGNNNNNATACGCCNNNNCNNNNAGNTGANNTNNTGTNCNTTCAGNATNNAATNGNAACCAGNNNGNNGTTTNCNNANANNGNGCNNNNNNNNNNANANCNNNGNNNANNCNNCNAGCATTNNCNCNCNGNNNNGCNNATNGTNCNNGNNNNTGGNCAATNCANCNTGGGANNNAGNNNNNNNACNGTNTNCNANAAAGANNNANGNNCNTNANNAACNATATCANNNNTNNGCTTGNNATGCCNNTNNATTTANTACNANNCANTNTNGNNCNTNTCATNNANNNCTTNNCNGNNTNNTTGAAGNCNNCNGTCGNCANTTNTNN
+
$"$$$#$!$""$$#!#!!"""!"#!!"$!#$$$$!$!""!##$##!#"!$!"!$$#""##$"!!"$!"$""##$$!!$!#"#$#$$"!#!#$"#"!$#!$$!#""##$!""$$$##"#$$#"!!#"""##!$#"!"!$##!!"$"""!$#$#"!#!#"#$$!$!"#!####$!!###$$#$!#$#"!$"$$"$"#$$#$"$""$#$""$###"#$""#!$!#!$!$$####"####!#!!"$!"##"$$##$##$""!!!!"!##$##$$####"#!$######!""#"$!"!$!"$!#"!$#""$""!##!"!#$!$"$$$!##"$"$"#"##"###$#""$!#$$$"$#$##!#$!!$$#$#!"$#""""!$!""!$!""$$$!"##!#!!""!$""#"###!$$$$$#!!####"!!$$"$!!$!"""$$"!!!!$#!!$!!"!""#"##!$#"#!###"#""!!!$#"#"!"!""""!"!#"""!!##$"$!#!"!!#!!$!!!!""#!##"""#""""$#""$$#!#"!!!"""#""#"!!$"!#$$"#!!#$$#"!"!!!!!#$$"""##"!$!#""!##"$""$"$"$#"!#$#"!"$!!!#"#!$$"#!"!"$"$"$"!!""$#$!#!""!!$""#$!"!""#$$#$!""#"$$!!$$"$!!"$#!!""$!$#"$#"#$#$$""$$!!$#"$$##$$#"!"""#""$$$#$#!#""#!!"!!$$##$$##$#$!#"#$#!$#!!""###$"!!!#$"!!!#"#$#!"#""#!$!"##!#"""$!"!"#!#"!$"#$$#
@r2060
ACGNACGCCATCGACTNACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCACAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTACGTGCTGTCGCNGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCA
+
#$)#'++#%*!**'#*+#(%)'!*%((!+&*'+!#%#(($*)("""#+((#"*(')*)!$%)!""!*(++*)'&%#&$#&(""++'+(#'+"')'$))&!$(!'%!("$!!**&$)'!'&#%$"%++)%%&"*(*%$!#&#*")%%$'%(&!%(+#*!%+**+)&#"+%%')#+&('))&(!($((($*$+%*"")"'((*(&%$(%()%""+#"!&!'&%($#"
@r2061
CNCNAANNGCNGAGNTNGNACCCNANTCGNTGNCNNGTTNNGCNATNAGNNNNNNNNCNNNCNTCNNACTCNGNNGATNANCNTNNCTNCNTCCNGNNCGTGNTNNNCAAGTTCNTTTGGGACNCNNTGGNNTNGGAANTNANNNCCCNCNNGNANANGTNCAGNNGCTGCNNGANCGNNCGCGCTNNCGNTTNTNNTGNCNGNNTGNCNNNTCNCNTCNGACGTNCCNNANGNCNNNNCTNNNNNANGTNCGNNGGCGNATGNTNNNNNGNNTANNCNTNNGGNGNNAGGGCNGCCGATNANNAGGNNGANAACNNNNTNTNNAANCGGNCNNGNNNNCNCCNTNGNGANNANTANGTCACNNCGNTCNNCANNNNNNGNTNGAATNNCNTNGNNGNCGNTTNTNNANNNNCNTNNGTTCCCANANTNTANGNCNNCCTCGGACNNTTGNCGNNNNNTAGNGNCTGAGGNNNNNCACCNNANNNAANGGTNCCNGTAATCNNGGNGNCNGTNGNNNNNCAANTNACCNCGNTTTCNNNCTGNANCNNGNTNNGNNTCNCNANGNNACNGGNNANANNGNTGNANATANNCNANNAATNNTNNNNGNCTGNNCNCCNCNCANTNNTNNTNTCNNNTATNNTNNATNGAGNNANNNTCTATNNTNNTCTTNNCGNNCNACTANTGTTNGTNGNGCNNTANTTNNAGNCNCCCNAGCNNGAA
+
#!$##$$##!!#!$!!$#!#"!!!!#$#!###$#$!#"##"##"#""!"!"#"!""$!$#$$####!"$!!$""#"#"!#$##!#!$#!#"!"!!##!#!#$!$!!$!##"!#$!##"#!!!#!$!!$#$$"#!"!$#!$"$$"!!$$#$!!#!#"$""!#"!$#""$#$"""#$""$"!"!!$#$!!#"!$$!"!!#"!#!$""###$!#$"#$$$#"!!#$"$!##"#"#$"$!#"##"!!!#"!!$$!$""#"#$#!$!$!#"!##!###!!""#"""$$#!$"!$$$"$!!"###$"$!"$#$"#!"$$""!"!""#!"#"##!#$"##"#$"!$$"$""##$$$$#!$!#$!$!$$##!#####$#$$""""!$#"$"!$!"!"$"##!"!$$"!!""""$#"#"$""!$$!$$#$"$#####!##!#"!###$!"""##!#!"##"!#!"$!##!#$##"$$"#"!#""#$"#!!!!!$$"$##"$#"!!##$#!"$$""$!"##$#$$$"$$$#""$""""$#!$"#"#"!!$##!#!$"#!!"!$$!"$!#!!#""!#!"!"!"$"!$!$##$$####"!!#"$"!#!""#!#$!!!"$###"##"$#""$"##"##$"#"#$$"!!"$$!!##!!##$$$"#"##$#!!###!!###!"!#!!!"#!#"#$#"$##$!"$"#$$#!#$!"!##"##!$#$!$""##!!"$#
@r2062
CAGTNNNANNCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCGGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCANCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACNGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAANAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAG
+
$&"%%#%#&"+"+(#*&#!(&"(+&(%'$*)+&*)'"%$#*#*''#'$&+$)')'#*"!&$")"(%"*#%')!(*'+%%*%+%$*"(*(*)"+""(#)%(#'&((*$%'++)!)%)!*&+*&%)+&)%*(*$)+#&$)"$&&$*#()')**((()+#&(%(&(""&+!)%)!)#+'&+!&"*'$$%('"!&%#("#&+$$*&"+%((**#(")+'(&'**!*"*)*$$+)&#')(#)%+$++($&!"##(*%&!)%!(#&'&#%&'()#++*#'#)#)+(!$%&!*%(''%+")!*"%(#!#%+*!!'#$$&#))'&"(!+$"+))+!$'#&&$&)!!+'!&#!*!#'*+&!(*!&')+")!$+(*!)+*')((")&%")'&!++)"%(%&("*$#++#&(*""!"'%!%(#')!!#&#&))&*(%!+#*((#+++$$"*$#+"*)!(*#&&(!&)+*!$*'()#%'$%*%"&"(&%%)"("!%)(+)+#'(""%$($+''!(!+!%'($++)"*#*'&())%++$*%$&#"$'"!!&$*$"+!#)+$
@r2063
CGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGAAGCGCAGGATGACGCCGNACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTNGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCNCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGNAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGGGATGTTATTGAAATNTGCGATGATGACTATGCCGGTATCAGCACCGGTGGNCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACNGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGC
+
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
@r2064
GCCGGCTNATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTCAATGGTGCAGTTCTGTACCGGTTTTCCTGTGACGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTNATAAGCAATATCANCAACGACGG
+
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
@r2065
GATTTACCCCCTANCCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGANACAGGCGAATCGCAATCACTGAAG
+
8<)21F1C)(+-#E0'D0GC=!':'"$D;2FB'4E5#*-E%$EF).07'GH?!-,H)C$*EF?"@GHHG+&H<3+!5)H+@G*5E""#(@;69EGEAE>C,$@7$&H7/B'=
@r2066
NCCGAAAACAANTTTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTNTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACNAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTNAATCAATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTTGCGATAACTTTCCCCACAACGGAACAACTCACATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCNCTGATCAGTTTCTTGAAAGTAAACTTATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATAACTGGCTTTTTTGGTTGTGCTTACCCATCTCNCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTNAACATGAGAAAAAACAGGGNACTCATACTCACTTCTAAGTGACGGCTGCATACTAACGGCTTCATACATNTCGTAGATTTCTCTGGCGATTGNAGGGCTAAATTCTTCAACGCTAACTTTGNGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGNTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGANGTGCGTCCTCGAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATANATANCTAACNCCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTA
+
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
@r2067
TANTCANAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACNTCGGGAGGGAAGCTGCATGATGCGATGTNATCGGTGCGGTGAATGCANANAAGATAACCGCTTACGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGG
+
#'$*$'"+)!#%(&'**)*'""&+&*"%$"*+$!##%+(+*!#(#(+'""&*'!('+"&(%$""($*)%+%)+#!$"&+&#)$"&"+'$&!($''("!(*!(+%+'"#*+$+'&(+&#'&+)%+!()'#)#$#+*$'$*#($&#($(&&$'!)'$+"&+)$$#!"#*#)$'*%+"!!%&'*#+$+!#$'+#($&#&")+!"&#&)$**#)%)&(#&$*'$!)!**$")%&%"+&)"##
@r2068
GNNNNANATNGCNGGGCNTACGCNNGAACCGNTGATTCTGTCTGTGTCNTGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAG
+
*"(##(()('&%$*&*'!&"*%*"##"'"&'')+)*"&&*$!"&'$&&*!$)&&#)$(!+!)+(%&%)#*(#*&+%#'!*&&'!')
@r2069
ATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGNGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAANCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTG
+
DHAA230GE>=@?"E03BG<1(!4;89,+!!>5+9@:9:4(@$8/2C0=&'/A&>;F#+H?!*!73@%@!<9?A.;*!3$@9=232D@3(++0"<?+>+B?"=:=<626%-,D85E,1#6,59+%;11!H9&A);C26<":6F3A#=FH0+<%%CE>3E2.>8>;?!;!?-C>D2.(,$7<()!7H4-G;6B%@G9)E'%HF74:#3*"?&$!;&91<)#-0+*'4;?DE925+BB@",.)@?78&E;(@93*7(0$D/?9G2C()F3@+/4(+;;GFE7A=+G'2.38(/H5:!3"97&B*$F6)"%?DA2:/6&6>/:G0E,$-D-+F2=?8DF#1,"7F.)3G-*!320%)B0,)=:&FDG'1;G+?$';2FDHA.!.,F$8F
@r2070
GCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGNAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACT
+
@,9220#6H?&F<9&".1:E>:**!"48!EB#$B&:E-BCG794*E,FC8/%F+"+A+;E5G1<+CD#:7-:B7153E++<9.933=:(G$:1+=/8BB2,81&$F2A7H'!"GD9B,91.G(4:!?+6H,9?,<&%)6G#
@r2071
ANNCNTCNNNNTNTATNNACCNGNNNNCCNNGGNTCTANNNCNNNGTNATAGCNNCNNANTNGGGNTTNGNGNNNCGTNNTNGNATCTTTCCCNNGNNGNCNGNGCNNNNCNNNNGNNGGNANCNNTGGCNNTNGNNTCCTACTGNGCTNNNANNNGGCANANANNNCGTGNNTGNNACTNCNANNACCANGNANNTANNAGTACCTNAGGCGNNTNNATTANTCNNNNAGNNAGTCNGANGNNAGGNNCNCANCNNGCGGCNGNCCNNCCGNCNCNNCNNGANCNGCCGNAAGNNNCNCTNNNGGCANCNGNNNNGNNANNG
+
#!#$#$$!!!"$""$$!""!"!$$$#$$$!!!!#!!!""!!$"!"#$""!$#!#"""!#!#!"!""$$!""$"!"$$""#$$"#!!$###!!$!!$#!!$"!#!$#!$##"!$!"$#""#"!"!!"##!"!"$#$!"$!!!"""$!"$""#!!#"#!#""#!!##"!"$#$""$$"!"#!###$!"$#!$"$!#!!""$#!$!#!"$!#$"$#"##!$!""#$"!$""##!!!!$!!"$$$#$""#"$$$"#""#$!#$$$$""!$#"##"#"#!""##!"##"#"$!#$""#$!#!!!"#!#!"$"#!$"#"!#!$$""#!"
@r2072
CATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGNGCATCTCGCCNTGATGAAACG
+
39A;%.H"+4A-/*-+E@'#4$@+0>&H9B3,5>%+!5%4/+7!*982,E$2@-C/B$&H3@%:()=&3?-
@r2073
AAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGAC
+
E)5A9D44B23)>1#);AG/C'(=/:*:;722G?#C3H72&7-C;#;<@E3D@=@@4#73.G<65>!F6#D)22&-#,'7F8E3/%@#59@
@r2074
CCGTGCTCTTCCANAAACGACTCCAGTACCGTGGCCTCCTCACGGNGGACANAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGA
+
@$=E#7:=F/:8>?$GG8A;H;=&A5<!(D-F29,*6.6<3';F14!&-@3+<0H%H3+6CAB-?=/#($5(>!<)"B1)!60)G,:3,,/=>8/F1;*G&5!2%7G=>3/($:8!@*>1:7#30:&%'75:%D(8/+#(<;"9<F?G,+&2
@r2075
CGTCNGCGNCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTTNTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAANGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGANGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAAACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCNGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGNTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGC
+
&(')!+)**(+$%+*"%"##)'#$(!&*)!+&#$)!%!%#""&'$*"%*#%)$#+%"!**'+'!#'%')#"'"$&+"#%#"&)&(!*#&#*)+'#!!''%'+))+&*%*$!'&#')$"#%''!&+!)#'"###*)!$)')$+#)&*+%('*%&#"*'%'("!%%'&'(!!*%*$%'%$'+*""#")(&&%+))(#"$'%#)#*(*#*!%"%#!''!*)%"($(!("&&$!!#+%("#&*&$()*$%!#+*&$($+*%++)&($#%*"++')+()))""+'#+++$"!"+!)&!'(&!'!$#!&&%''+#"*(&+($%)*)%&)')'%!#"")!(('+)*'%'#'%'++$#)(%#+&!""'%%++'!$'#!+#(&$+""&*&(&'&#")&")"
@r2076
GGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAAACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGNGCCACGCTCCTTAATCTGCTNCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCNGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAG
+
E:=?GE9+B8?.><.=G!5@<?G&'=C>-',8/G:4"-EDC187A,F&-%C<A;"+#,*?"G9&7$3,),1(1G"-&>6?'#107>D2,;9F?=2-B>F+(E:)%'"F@022(;)E8-0$.$47?.5,7F1"->23"/:C.!"<F/$1;"&9$8%9:HF*,0<;#-8G199%#+36C"AC(7B<E+CF/8#5',-7"08BC,&7,%)!431%#:-&E"#D04:7;D08?B3>#"+B%*.;:@=-!D?"0%<8A-='@H6&>3%=GG?')#<8A&@=.C:46FB01C@/2:07:23"'*47)H?45C;?CC@5-;@$A'AA%%/,A9!+,A&)G)5,AH&4:D#:4*F
@r2077
GCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGNTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAANCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGT
+
?:""5?A:H2$%@,4A:1&6A>$-7#1H/5!1C6DB;26-D7;>.G')1>@B%C@+=>H#93CE*,HH#//<50E4&=;/?-#;0=G41&%0"115466",$@&@<B+,@78!F!@#C0*E1";A=G)"HC+E&-,;H$55GG*(G@6D7FCC!-/,$F?=
@r2078
GATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGGTCACCCTCGCAAACTTGTCACGCTAATCCCANAACTCAAATCANCAGGCGCCGGACGCTACCAGCCGCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATNGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCANTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGNAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGNCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCNGTCTGTCAGTCAGTGCGTGAAG
+
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
@r2079
ATCATGGCCCTTCGGGGCCATTGTTTCTCTNTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAATCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGTCAAAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGNCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCGCTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCNGCCG
+
06#%.D#,/F(A61"&A06*7@)%*%%C*9>83.GF2<),.AAA(,;(4,F/1";G?(CC8!-/G9<&H:2%@$B?84*&!.H$'E15="2>'//D!:D1D6H,#?58/+0(.FHBA4E4-.+*&8>46H64EE?7:8DE;.$@;0)9!7->$69BG"A51;C1FC5D479'*:4A,?F3B5>H7%52#"H->=)91,=G5E1"0&@#(8D+5<&7E>4%1*:&+$;/32$0/:BC!;<"<<9A1=1A=EE>E!<GB@A=&"F1/0C0;DD99)+!0#+45947<(<'$7&#2:''?!=.?&++;='8E=(@92F3D!;/$?5"23B1(/-5?5#%6'E>E%+.::#,93+H*91#!@?&/;.62=8:@
@r2080
CGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGACCCTC
+
!7E;4<%/1'3CE<*BB>)971FB-@,$F0?2700H(1-?D%#-')3*!:GEG<3?,?D?1
@r2081
NATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCNCCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATANGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAANGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCNGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGATGCCGCCTTTCAGGGNTG
+
$HA@@;&%<2)/(=>EB49$A/BA&&,8??<ECD5"2"1&G@(@A%/#/C%C;93C"AA&,/5=21&E<E"F@)/.959&&C)-1(6$G:D3-*BA:4B60$%,$7+37-0H1#0!A2$1)9-&"?:7.!D5D!@)04F>$EGA+7$A:3;/(!.7$@!5-1"G,*7/&)C-#;8<'%%$2EA+=81F1:9DB9+9F1#:.;:)*(A=A?B+FF.7<"@112HH=020A?>F'!8?:=""1%6,8E;F)6)7>(-8DE91,9+#E;HE4!78B*505&$1&=BF1$!78@G):#;C"C.7%/DB9"-@D/..D1#&7<>0H-11#@*4)8+E(C1">/<>8.9/D,2>6&(?,H$?."(EBE,@%G;9!5:.%!)*+F>C392-==*5!<&23G4D?1=G:32C"D<>H@!82/H-3A%)09'>4(H'--H1"90B;&/&4?>HE+*3BC'>?C@8G#G#.4>AE)A7%97&58F%G!!9+43A:3<*96H>')0EE$<1:=$(=?<.64%@4=)A*E!8F4;/1"?7H227423&'/(D9(&#;75$C&>C:!41>$0A<:96E>37B4.>69/3:$..5-1'EH)BE4*9+'1):5-'H-'7!6>$#36=9("2*(--F"F5,:
@r2082
TGAAAGAGATGCGCTATTACGAAAAAATTGATGGTAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCNACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGNTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCNATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTANCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCG
+
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
@r2083
GCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCA
+
5@&35*.@FA"8*(G<:E>8*/=+;690#96*96*@6?F&F!BC*A1?1A(>'&A?$EB&E9:*2+>015D75'#>.2C1<&@)#H%B!7)+#?5@%+H--$D;)(4?0/%%+&EF1G@91'<,#+D,7EG<
@r2084
GGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGC
+
>:+4+D5(DH-6;F-H3D)$4#@),!!.C?;/C;.&-H+H@18/;)#>C42$H<>59<:6-<59258&#,,<'/5&-/%"H+EH>*2&$EF(H%752+2=F1:#?$H05C&.2"-,6C.F$>(<=FG/<6,FB@'=G(;H(D,!2;@B@,)CDH5A5+*>92)2;6$9&89)CH3@H3=1>'!!2FD;C-,;:*92)C%9<(7&?B483/%=!H=(@>"=28AH1)E0<)'5%DG@15==@4E+'3?(*;.,#C)>C)(C.':%)/1B@E5-39F?
@r2085
AGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTANCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCNTCAGGATGTGATGGAACAATACCAGNACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCTATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAANAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGNAATGATTGCCAGAGANCTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTAATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCNTTGCCCTCCAGTGTGAGGGCGATT
+
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
@r2086
GTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGACGNTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCNCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCNGTCGCATCATCATGCAGAACATGCNTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATNCACCATGACCGGAGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCNCGTATGACCCGACCGACGATAT
+
?=:3"<5>-D0?:08.?-*E4.?+)GC'A>8+D6)7,7)4!H;0'5$9?4DHG?"FH.9E@0+9"0+=#5%%7(C03=+3,4GE@0*97)'H#;=H%&.#E/'"G<=4G1>!,.,C!0$'D7/4C>'0D0%C&/>="*1)#'"6+&'&6B?13?%!DB@38&!2EB%2:;8"$*7F.=7..A&3)9?B-,)7A9,4F=+5AG7,D(:(>A7DE1DB>766@;C/0A9"7-H,9(:H!=(3>*DB"2H>+(8H/:@EB5+&6D.C%55"A7C')4%)CH""*/+'/G.3D9?(/7/4C2":C@8B8.=:);D44+!&$&9=)H#<GD,98$D$1C98-E</.@!2G,,A8'-=3H,F*?C;5559--F@><(;@(2"(@2H("@(7'A"@)-3>,#;;'+&<%?9@H+E*9
@r2087
ATNACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATNTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTATCTTCATCTCNGTTCATTATCATCGCTTTTA
+
0D-;(E'/9C,E3A?4F&D1*9-.',;4050G!-.-D5!-7)29F>G9"6*D:6<'(4@63G4/?#=)@+?;&:D#,:(',3?FC8'(%60?5152::$74$>53<F"))+8)"7,G/7EC=%E+&-@)9*?-"-@H:(8C#:&$+A4FG/D""5"4B%109+9>HHE#9;#)2%C=9";73)87-:>#(847.$E,HE#5%6
@r2088
TCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACNTTTTCATGGATACAGGTTGTGAACNTCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCNGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCNATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCTTCGCATG
+
HD*7/298BFF4G<G.8$$!"<78F0*014-9$@5(63AE+5'&.ED<+?38+"$9=,6!2/;"8)<&H5/15A="?:/EG@;.1.6:G<%"9*-1+*;*+=?2'5(!0"="4=7".1H@D*>D($7(EF5"?E0C<E4/<98*!H";&%70FG/"B+:1>;<69BF$%->1B<3*9#+DF(3F$'::(1!130E@##=!65F)@F/30C#C>9!9000$A8,-)*;=,5"!08?2"*;EA8'&:++<2*'37(43BC;8D>>&7=C$B=+7@A5B/E<8!.H?.$@B/%A=?49%2/.92&<7DB1%G<3G@B,E*63->6(G52G4=3BF547D05H<AD7*'1>C"1>?8+1/5G/AF#?>:C%H1(*?G&?+";/+'F1+48'8,G#E&?#6"3#:>%1"9D13B@>'"%8H#FH27)H!GB)+1&.""'"$!7G$6%+2=0+(;;*-A()'G#98
@r2089
NNGAACTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGANAGTTGATAGNCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGA
+
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
@r2090
TCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCNGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTNCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATGCTCAAGCGCGACAGCTGAAGCTATATCTTCNG
+
@?8B&.%6=)*82"-7@.7%;#1B+:<&;<68/$FFD3C(H:1E:2;!0.;)3'-8#$2*7?8>"!*<#&%(/@%D;>(+/B&>242468-50D3=0@)-0B::?>B@/'<?*F-9+D)?95;89E+B@&D=)7@3-;0GA!=+-G23@0G::.>D):"8#-(E?#?C#!:A=;('+',?:;2/AD$988*6092HE7>2H+(9%GG2&$3G<)5+!;G893=*&6C7$/DF#:2BBD024C<*F3A6H"<!DE9*A
@r2091
CGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGCGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACC
+
0(,1>?DGE3+7>4+1"D/H!$F,7G$+2B#5)8,D003?A<>("!@AD-2?919(D9'&0%)31#/*08B4*#4GC/A'<=9#%6-?"D)&<CC5EH842,831).)5+/6?*2GG"??77/*?GE/:/>EA"A,GC@,&>C;-8&-+;$3BH?6@B1=H&"'@F#21.GE$!!8;4;2FHF&1C@A;$B#.?'
@r2092
CTCGGGGNTGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCG
+
7+=1-5;;2&G6#8%/,2/#!?'.A:'B"5!21>A=AG*02*,F.4H'"C#2-+B$
@r2093
ATCTTTCCCCCTCCGGCGTGCTTACCACGAAGNCGCACGTCTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATNCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACCTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGTTCATATTCATCC
+
5+:=F8,5@=%74/*:?<0-/(":5&<2C:D$H,F)C$',@631:155(+3'$74B;5:>8@#?B?E(/.>,0!E$4+1<;;*').99*,C<4HF7B?)<!/97')H"-C*7*9&/D0":0,).?1EA+,:,<'=29:21*">FC$03>G9$G7E&*%?<.2,+B'-"8.6;0B+:10626<F)B:E;&$)C4-A#9+CF$.*<)2'<D%&,-;@<!!,.:(64!12'%A57
@r2094
GNGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGANATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGNCTGTTCCGGGTGATCCCCAAAAGGGGCATNCGTCTACGGAAAGCCGGTGGCCAGCATNCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCNGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGA
+
$*+("&+''+)%""$+(+*$#"#!!&)"#"'%!((#)%""$+(!+*(&$(#)(*+!#$%#*++")'($)$)'*'&+&"(!!%!!&"##!%'('&&#''#!+(!%#$!$%!#)*%%(%+(&)*)!!$'')"&"$$#%)*)&'$'"*&#!&$(%))*''%**$+*#**'%"%**+'"+$#"%$$+%"#")!*$%#%+'''))*$&""*$+&'*)&$)(*"!+#("%#"#$$!+%%%&*#)($&(%$'"$$+#+&('+*')%"!$&)$)*+"$!"*)(*$'*'+#+*&))($$((*"'"!!(#+$$!%*(*!)""($!*#*)')*#&)#%(%&!(%"!&!)+%""*$"+)+#)$)#$)"&#+)#*
@r2095
TGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATAATATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTT
+
7.*3"30#/E3DGD(/)8=-,!'2739D$B%,.98?=%*6*'21%#+G0H)C=-?<*<>G8C42%(22$@9D.9G-H4B9&7$26$E#5.FE</&>=++<%*":/6(%H9;?@(27,3$4=E$H*GFFGA5=7)$?9BGD(F."3)$!'!;&C$G#2$2"5E2086.D,2$**75H,>@%6G<?)C48"-#7+?&C8$CH6&@BDG=20E.2&3-DH-H/'497/E:G>G=!C@8-1H,A86:-.81E>-7(2H?D<>.7#
@r2096
CGGTAATATCCGGCATCNCNCTGAGCAGAGGTGAGCGTTCCGCACGAGATACATGGTA
+
60F3#91./2)*B>(%0/&0+54!#F)2E77<"0)<);'D!347"%CC?A$H1A;49B
@r2097
GGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTG
+
>!C4<9/H>!353FD89-8'G-,'2BA7-:%/,2"3E@$,HF2,&&?*80@,*2E::(-;A<E(6@?98.*;++</*.1=49*A6;=B*H?E4=1A$C%5-5@(@-?C!&<'2=4?;&7#-29>5!20DDB<GA339C-0E1:%:3C*8D/4G1=A1$@DHF&-0HB;)E,?-!A-#2&55'=B3H*<:F#'GAF9C?#00:H7-;+"(*%C&D=3;(>,3?'G2"+1.((A*9FB/7)G%#/DBH'6@G1">8#73'G+5%(,'@H6C&2=>%<7E#$.=B5E)('4'#=<@$/+
@r2098
CGANAAAAAANTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTC
+
"'"!!*#%$%!%(+*+(!)$#%"!'&%$()$#!")$!&"%$&")!""#(&'#%)*%%'"$"%&*$*"((+*)'$$'+*(
@r2099
CATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACT
+
(42-37=4$C*%45C<;,H"E;CC:02"?<HAF(<'31!$FDB'246#$:".B$?%3"32&%B3)!;B5E*C1A.H!06182B-79A(8G03*=E
@r2100
GCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAANCAGGCCGCAACGAAAGGGTTTGATGACCAGANCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGCAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAG
+
7)9H324B+$7A./!55D.>+03A2*(AD/>77C63,BG1!-?$257F!AH)2)34E9=7%<2.%%/'#5;2*16+B'3EB).,-/)E&5C2;757)87"<(D'G8GB9A3%+'6""E*.!G@?<@<==29%4$)6D/?F);*09D%-=460*&%4E":F?2"A$0G=1/$,G5(.G;+0%3&5)DE.2H<4=<:7;46!G#9;9&0C).GG-9A@104%E@G10(!;3H',),&GA";E(G*%840E$F8-:3D3
@r2101
TTGATGGTATTGCTCAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGGGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTG
+
CC9G967@,@9D=(D.;/(!'$;%#;(C&27<8B$"30DC?-#G:5?=5H=4!H39F8)+<9$(?C>B%(*"#8D?AG'(HH<7;6.?)#AD(7=2G&/<H9)FF/?5;C8:7=6F53,40,%CD=;FG)!B2%%5-)"6!&>EF1@,5@<$*4@((A-=4,F-F:ECGB2+>(/<9-4-<;$E9(;/ABB-10'8;12@',3"!$.&,B((&.CE;)15G4(,?;-76.G6@&#,&0'F'H8%!%@D92HB*;G&'$A&57@56:H;H4A5H<<
@r2102
ATTCTGACGAGTTCTAACTTGGCTTCANTGCACCGTTTGACAGG
+
@84.F$>8+);E5*/<2E-::,G);"+&76C?)/C'GA;".&6E
@r2103
GCTGCAGCNCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTT
+
='%@4181+2G,=9(:?1H9HF$27*D@&,!>A205":/4<+D@4/"%3)-.):4-$".*
@r2104
CCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGACCGTGGCAGTCGCATCCCAAACGGATGTTAGGTCATAAAGNCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCTGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGGCGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGANCAGAAGGTGGCTGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACNAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCACCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTNATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGNCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTNCTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCGGCATTATGTCGTGACGGGATGAAAAGTACATGGCG
+
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
@r2105
TTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAA
+
@DFDC2,$#!?5&<:&.%@4:16/@'/G&<&=/-G./2<+5<C":;>'6H96H1H$&&*85"G=!35E0?A/'4C0)6,,<%<&:@A(7F.H0$007=7:-(:6.E-1H+;A#>9-E=)C*(6E>"5=5G;G=-!:$EBDB87=
@r2106
CTCTNNCTNNNNAACNNANTNGNNGACGNTNNNGCNGNNTGANATAAGNCNNCGNTGNNCNNNANNTGANATTCNNTATTCTTGNATNGNNTGNTCTACAGGNNNNNTTCCNNGNGCAGNCANCNNANNGCANNNNNCNNNTNTGNCTGCGTGNNNAGNCNGTANTNGNANNNCCCCTAGTNANCNGNGNNNATTTNNNCAGNCNAAN
+
"#$$"$!$$$"#"###"""#!!#$$$$$"#$!"$!!#$!#!$"$#$##"##!!$!!!$#"$!!"#!#!""!"$"$"##"$$$#"#"##!#$!!!#$$"###"!##"$$$!$"$!!!##!!$##$#"##""$$#"$#!!!"!!"##!!!$#!"$$"!!#!!!#""!$$!!#!!!!"""$###!"$$"$##!#"#"#"#$!##!!$"!"!
@r2107
AAACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCNGGACGTCAGCATATTTGCTNTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGAGGTGCATTACGTTTTCTTGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACTAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCCAGGGAATTACAGCACGTGGATTGGCATCAGAGCTGATGAACNGAAGNGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACNACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTA
+
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
@r2108
NCAAAAAGCATCGGGAATAACNCCATGAAAAAAATGCTACTCGCTANTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTNGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACANTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCNATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAANCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCAACGCCGGAGGCGGTGNTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACNGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCNGCAACATCACGCNGACGCATCTGCATGTCAGTAATTGCCGCGTNCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATCATGCAGATAACCAGAGCGGAGATAATCNCGGTGACTCNGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACNAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTANTCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCNAGCATATCGAGGAACGCCTTACGTTGATTATTGA
+
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
@r2109
NAATNNNNNTTNNNNCNNTACNNNNAATNGCGNNGNGNNANNANGANNNGNNNCNGGATNTAGNNNNTNTNCGNGGNATNATNCTCTNCGNNTNANNTNNNANAANAAANNNNANNNNNNTTNCNGNANNNNANCNNCGNGGTGGCNTNNANACTTANNANTAGTNNCNGGNNNGNANNANANNTTTAGAGAGGCCAACNCGGNNAAGNTGNNNNNNNTTGCNTAACANAAACANNANTNNCAAGAAANNCANNGTGTNAATNNNGTNNCGTNCCATTCCGTNCNGGNTNNNNACNNAGNTATCCTNCGCANNACAGTNNTNNANNNNNNNACANANNTNNCANANTNNNNACNNNTNNNNGGAANACGGNCNGCCNGGGCGNANCNNNANCTNTGNGANACAACNTNNNTCNNCATTNNACGNNNNNNNANNNNANNNNNANANCT
+
""!"""#!!#!#$$##$#!$"##"!!"#"$"$"""!!$"#$"!!$$"!$#!!"#$$!$#$#$$!#!!#$#""#!!###$!!#!##!""#!"#"!$$"##"$#"#"$$#$#""!"#"!"!##"##$!$#$#"""!$$#$"""#!!!$##"$$!$$#$#!$#$$##""$$#$!""!$!"$"#"$#""#!""!"!#"$!$#"$$"""$##!!###!!"!"#$#!$#"###$!$##"$""$#!#$!"!"#!#""!#!!$$$!!##$$$$$$$$$$$#""$$$$"##"#!"$#$#"#"$##!!#!#"#!#$!""$$$#$!"#$"##"##""$"!#!#$""#!#$$$!###"!!"#!"$!!$"#$#"!$$$$##$!""!$$!!""!$!""""#!""!$"""#$#####!#""!!#"!!"!!###!!#!!""!"$!!$!$!!#!!!"!"$"#!"
@r2110
CGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAA
+
3<<>F!>3/77E619:B/'83G(G052=!;'%.->6)*;0$$3CH7";D%@+8<E)<57&-H-%#=084$
@r2111
GAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGTAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGCTGTTC
+
A!,>!2834*+36B:&H.@+7G5;")7,!/$*:0*=9EDBH@2"#2G3=D$=3>/:*<@:!A8>B74DG!@G8<#$:38+,AE<B@=G4<6/*33</.,H8824;6<FE839*=2446H0G;0(;%'6D=4>G'&G))%#:H0/A0=@,'5=;+(9*C1A7C>;$G<$6=DC$*)6/A7HD&*7?(D=:047/&*?;><?9;3=F?F/G77?H)9%+8/01,2(B%#1>2*(!.$)%87:(0BFD(.
@r2112
CACAGGCTNTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCGTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGCAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAATGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTCAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAGCCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAGTCCCAGACCCAACCAAACCNATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTACTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGACCATTCAACCAGATGGATGCGTGTAGGCGAATTTGCGGANCTATTA
+
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
@r2113
NCGGNAGAAAACAGCCGCATTATGGGGATCCTCANCTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGNACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGNAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCNCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTNATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTNACGTTCTACAAGTCCGGCACGTTCCGTTAAGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAA
+
$)**'+($%&!+(!**("*)'"+&#*&$*("&$$"$&'%!$(#'("%)%*!)$'&'+(+()"%+#(%*+&+"&&!!"#!#*+"*&")!*+#)!!&(+$(+$#"""#&'+$+('%(*#*"%#)%++'''$*#%)&)%%'%&&'%!$&"*&+#$&+&!*$+%'+'%((#)"#('"!")!#'%+"%#*(+(&'+&+)#)""%&()!""&(%("'$**"&'!(%(%&%+"'%%**)$#!!%(%*!!""#(%#"&(*())(#$#+#"&+'($"**""('+++""&)*+&%+!"&&*"$#%)&))!$+(&'$&)&&($&'+(($**(!(&#"*$!'%!'()'!)!")$+)#"*"+"*'%"'"($%(!***#()#$#)*"!"'!*&'$$#$%'+&"(%)"%'"*&&!%*#$##(+""$!&!&&)''!('%"'+$*#(+'!(*!$"*+%+#'#()!***+((!+$!#+((('('&*)&!%#'(&$!$&%$#)%"!"')'#*%(+*++&*"#&!'$)+##($%+"#*(+"+"$%!'"&(!)+%)!")*+#*!%&$"&('*)*#%*("&
@r2114
ACTGCGGGCCCGTCGTGGTCCGGCATCNTCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAATATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCT
+
'+##&'%&'!!++#&!(*%+(!+$$+(&)"$!(+)$"#!+$$%(#$%*)*!+'!+*'"&')()!'#&%'*%(+%(*))#%'*&$($*)($"*)*$$%(#"')%*')+'!(&&"%+*%(*(+*&%&!%*#('&&#!!!$+#)!('&"%("$"&)&$$''""")%#*##)&%)!*#')(!*(&'++"##!&''$'%+*$!*!!%&)#$"$&&$(*)*)))"$
@r2115
GCTGGCAATAGCTGATAATCGATGCACATTAATTGCTGGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTGAGGCCAGTTATCTGGGCTTAAAAGCAGANGTCCAACCCAGATAACGANCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACNATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATGAATGGTGTGGACAATTCANGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGCAAATATGTCGATAAATGGGCANTACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGNTAGTGGCCTTTATTTTTGGCATAAATAACANAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTTAACAGGAGCCGACATGTTCTGATTANTGGAAATCTNCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGANATTGAAAGCGACC
+
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
@r2116
ATCGTGGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTANCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACNAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAACACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAACTTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCNCGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTNATAGAAAAAGTGCTCCCGGATTCAGTGATTTAAGTATACCTTTTGAGGTGACGGTTA
+
(*((*#+)'$)+(+")*%&"$!*+'')*&(&&&!+&'!()'++'**("*%(()(+'*$$##&&#%(*($!"'"%+&+%+*"()!#+)'#'(%(!(&#")"+!"$%!$+(##'+&%&$'+(#%'+'"&+"!%"&$'*!$*'$!"+'&#&%)'###!*)'"+"*#%%!*")*)&)+)'*+(*&$(!)"%'$'!&$&!%*%')##*$&$*(*&'!&)%"!!*(!&#+$%$('+'!)+'+(%&%#$$$&$)%#"!)$!!#"%**)!#%)+$'("#"!$#**)'#')!)"%("$$'!)*"#)"'$*')!$%%)*!&#!)("&$*("%$""$")")'")'(+%++()*$*"+*(%&"+!"!)$*#%(%++$(+*''*%#!%)$%$(!))&)*&(%&#(+*&$%"++"(&%!&((*+"++'"!*'("+(+$)$%(()%#(!(')!"'$!#'&%#&')*")*%("&'%(!*""%")(#"&!$)*&"(*)#)###$)&&+#%"%'%++%"%$&$+(+"*((!'((%"*!'*#%&!&*)'&!"!"('$*(($#&&)'((##!#*()'!$(")$+(%&+)%$&+)##%*&!)%'()"&&#%)**$)'!!%!%&(((!&!!$'%!!!(#+$*%(')&$+%'(#+'#!!((+)*#*()!+#'%'"+(""&*++&#*"$+#&!%(!(%'!%)''%!$'!)$($($**&"##$')'*#*#+'!'"&&*$%#+%$'$+#*!&&+%%&%&&#)+"+'"*+"##'*(($'(+$)"
@r2117
CGGTTGCGGCAGAAAACAGNCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGC
+
AA+,+?!3,1'%0>&EB'511EF-<?--F<:9.**=8*%"#==8%1=%/G&/@>"!@-:-D?-G47E?D%$5E
@r2118
TCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAG
+
+60-2FC<24D4@#<B417:'C>)?#,7<+,D<G8(%A=&2!.,@@%((%B)$#,E:96HG84F5DD2%8C@1EBC)'9;%,
@r2119
GCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCCACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACAC
+
(+)+!*%"+$%#&!+!+%*"(&(!"&#%+(#*##'##)($'$+($&(&%*'###!(&#$##'&$&$(""*!)*++!&&)!+!!*%*!%(%!()"+%%!((*+)+)+&+!$+$"%($**&!*(')%#""#%%%")**)()&!)%+**'"##)()'+*!'"''#"%$!!$$$$)*(%)*!"&*+*!+'!$&%"%'&$&$$$%*")!**%!&&(!'#'$$!&"+#(%)
@r2120
CTTGGAGGCGANGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGTCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGNCAGAGNTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAAC
+
$!)+$'$**"("&+'($+""&$&!(&%%&##'"*#*+)&*%+!*+'))+!($)#"$("!$%'%)(&$%)"%'$+%&!$$!'%*&''$*&&#&$#"%!'"*$%!"!%+)%#*'#((%'""%"%)!"##++#((**"'!*!%$*%'"&+"!+$!#&!#)%"$'%$%(+#)!%*#+(!$*(++%$&"+%!!&)*$&"')!%'(('#("$&("+$()(#*)#("++&%$'("**'%!#$$*%*'#!""$#*
@r2121
NNANNNGNTCNNANCNAANCCNNACNCATTANTNAATCNANNANGNNCNTGNGCNANNANANGNCNGNTATTNCANNNTNCNNGTAATCNGAANNTNANCTCGNANCTGNGCANGGANGNNNGNANNNACTCCNGNNAGTNANNGANATNNAGANGGNNTNTNCNNANTTTNTAACNCANAANGAAACGANNNNANNNCNGCANNNNANAANNNNGNTNTNCCAACNANANANNNGTGNNTNNGCCANGTTNCNNNCGNTNACC
+
!"$!#!!!###"!#$#!$"#$"##!"!!!#"$""#$$""$!!##!"!""$"!$$#$"$$""!!!#####"$$""""!"#$"!#"$!"#!##"!!"$!$!#!$$#$#!"!""$#!"!$!!""!$""#$"#$!"$#!$!#!###!!"""$#!!"#$#!#!###!$"$!#$"#!"""#"!#"!$$#!!"$"#"!$!!$$!#!$$""!#!$"""#$!!$$!!#"!$"!#"#$!###!!!$!"#"$"!"#$#"#"$###"!$"###$#!
@r2122
NACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACAGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGNGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCNGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCA
+
&E)<,.F1"+=G?GEHE$&(?1108=)=0.G(#$$0)B.((++)FE-?=)1)B2.HA6)(?7A<?"*F?$2D:?2AB,?8+.26,"5E1;.20HC2-*=&*H>#BG*D(*#->@F26.;08"&4.F1.8<!'@6:#G0+0:@,:./""7--&/%9B.31/.*7:D+71"9>FG#?)H?!*FG.2?+)3E0D>-#93@G:A7=DG>H64.E91$C.&5??=!!=92-67D9*+&8F,B,
@r2123
GTAACACACACCCCAAAGCCTNCTGCTTTGAATGCNGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGAGAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATANGAATTTACTTTTTGC
+
,C/:0=;%512/!2"=D#@E0;8=2BA:+F63--DH"1?$?D1:20:&:7AA/7'<AA*8&%,FA:$B.ECBB4;-7*$!607@(:#-6:9$%)D.+D,3F3&==!GF;*H5!!A'B(>DE-!0AH0:'H7%5F>865",:"<-B#F-):.25)%C@6-E%>#*70<7E?.$H%6+48375#*.E,H&13/6'E7G.*C9C)8
@r2124
TGCGATCCGCGACAGNACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGANATCTGCCTCGCGGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTC
+
,'*!(0)589:HH!HH#EDAH?8)"42FBHHD&,;1A<H9A:"A86$(28-<&8+%8G9,6&@,/&3<+%15+7H%1CD@3B7++5HDH?DF*=?>1#/6%?>6H5C=6600@5,>>=G,&2('(,C&H86-F6;<+=6(C8.A4,AC':'A)(G)G#,2%6)7)1F99A(G0&&=H8.G"3D"##C>C=)'=HA+G8"74@H=&-=D4)FB.+:>/G)7:;$?-7C!85):,0;,26'#B<AG69;?,8D302>"&*?@#9@=<.<AD16=15+
@r2125
TTATACTGCCCGACGGAAATCCCCGCTTTCTGTGAAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCNGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGC
+
.)<6'1>(A3D$@=%0"7"H@+(=;@=>@=D7E+CEF0132(B:"+.*1"0-BCC,HH!>D/-=3@0D3",,'*42D=!*0>*=2.#3-=/'6(>8>;,*!F1-:;FC!8!76G&;-,.8,D;*:AB+8E)H(5E+-+":H6,&.?=,'#-D)EE',70F>+C*<9%>1!!CG:(1.A$D89%,E+8,"?9*!)-F)&$*+(6G0;,/0(?-C-1A'+(5E26(C1E=7@A&8B")9/";C,)-G+4%+0@.D,(;2>%G*;=CA$2E.*F*/"04(<D
@r2126
TGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACCAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAATCAATTTAGTGAATTTATCATCGTCCACTTCAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCC
+
4"!=+2.69#5042:+.-'*%?:&H!4H+!6"?<E$#'=H/0D7=/.,=,%08#4>!8"1;B7.?(F6A'-H*-+#4H"B.A9)19'>(%;C'G=*<9-!24.(8+>FG?+;"5"D!&0D4<D<AA*&#?;/:721GH&A%:(7'+5D6)ACD/CFD'<A/@/$'2&/A";E!D".,(2GG*5H9E,7-:B<DDG?$A#:B!*5@@FD<#.6.2#4/%G%C0;E%0"1><<*!A(!B,:'8+5!?<C92>B0@&%.<@&B7H4*(;--7/!2H!>,H8B#@D"84F!*=,&;8D#3+D'E/:$172H/-7+<9-"527?E92>/EC-!H?'-04B:C<.(+?.(/F"-&>%!;G0*E>@83H8$+4><;C72A16,G.4%9>BA6E/$%'$'&'.1=0!A>(%
@r2127
TTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGANTGAACATCCCGCGTTCTCCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTNACAGACTGCGTG
+
5:8+A96<1%6*2D&"9+8C,*?$/@39.@6;(G0F@F@A/"F?B0HD,60;.F2$@C##8+54G?B$,6FE,A:7=$8H?(:*BG%4()0(@?<A7(?<&'F07"B=/G'!.-4C94-'&15&E;6E='<(*@8E4)62-?G54HC%461D;F"'(D-">4:5'E"$EA('D0(.$,#!=)D;#"
@r2128
CGAAANAATGCCTGGTACTTTGCCANCTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGACGAAA
+
+6/#/(67B$:,;<B!C0G=%2;A";1))-:'$/7-&<%C8*6":0B>!/D(9(D$GAF*",@4%2F>B,(.CC96A6@A
@r2129
ATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATGACCGCCNATTGNTTTTANGACTGAACGCATGAAATATGGTTTTTCGTNATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAA
+
)+&)*&#%%!#&%'"*()+%&+++$%%$%')$"'($"#!%+&"%)%#(*"!#"!())*"$*+"!$'#%!("''"*%'&$(+!$()("%%%"!#(*(!*(((*+%"()*++$&*+$%)!$$*!(!*&*&$!#$''&(!)!('("##&&(($!*&+()#+&'!*#*+#"'('$#+("+"&***"(#++!+('&%#!&$(&(*+#!)+*&!%)"(%)
@r2130
ACAACAGCCAGTTCCATTGCAAGTCTGAGACAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGNCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCAT
+
.>4A5;E27&8..<*/>.4(:38%;F3C0?=$H@#1!4<65!E?8F3G<>:"$C$0"B>>>4D;EC?F,@1/"3&.B5==5,;,7F<*)>&C04!7&2;60%H?">!%@@G/9BG8=;?69>+&AB+#AA"-F@;,"2!?@6@%13<F;0?AH%F@&HA%9/E+$E3+&&E?4343980,+DA+*?/1*+713+9&-<=84+9$8(C/<<?(>D2DACCH+D9(1?#9H&.AH$AE.C5%*$9%)
@r2131
ACACCGAGAATGGCTTTTACNAAGGTTNTACNTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTNTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGNTGTGATNGGACACACTGTCAGGTGGCTCAATCTCTNCACCGGATGACGAAAACCAGAGAATGACATCACGGGTCCAGATCCCGGTCTTTTCGCAGGTATAACCGGCATCAGTAAAGTCCAGCTCCTGCTGGNGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGNTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAANGGNGTCTCTTTGTCGCCAAATNTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGNACGCTCAATCTGACAGNTGACTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCANCCAGGAACGTCGGAGANCCTTCCTGTTCAATATCATCATCAAAACCAGCAAGTTCCTCATAAGCCGCCACATCCACAGACTTTTCACGGTGGTTTTTTGCCGCTTTACCGCCCAGGCACCAGNAGCCACGCCCATTNGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGNGCTTTTTGNCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGNATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCANCCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAANACCCAGCAGCATTNTTGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTANGCGGATTCTTTCGGGAGNTAGTAATTAGCATACGCCCATTCAACGGCGGNCTGTGGCTCCGGCCTGA
+
$$(*%)*'!$'*("'"%*&""#'"+*$(%!"$&#++)!)%%+&%%%"$*#&((&'!*!""*''*#+"#'&'!+**##)*%+($"()$'"%+"(&)!+&#(%')*+'!&!)!($!*)(%$%&+*%+&))**!*'#&#*#(("%))%&#++$*$%)%!+*%)%)%'*&*$+++#)'#''(')&$)*'+#''!#")*')'$+('*((*&"*%!'*''+*$!))#$#+"$(&)+%(%*#%)"(&*#"'#**'!#&(!#%$(+!$#)!$%&!#"$!$(%#(+))!"($*$&$&%++&+%"!!&&%("%(!""#)**%$)+$&$'##)')%(&''(!#%'!&!%+&+)"(((**"&&%&#!)+"(%"$"!!)&)&#%(&*%*(&&+!'"*$#+)*+'#%#!(&#%*!&)(+"'&##$*'""$)&%"##&$&%%&$'#"*$!&"*#)"&"&#*%)+""%((!"%)++'%*"*+"!*%%''#'#"$'(&&!%"''!&&%$&#'(++*+%#))'*##%#)"&+&+"*'#%")'!&%$(+'#*(%+'##*)+##!$##&(#+"'$'!#'!#!*(#+$(+'!")*($(*$!*&%'$+(&"$""!#$)&(!!+#&$$!((&"#*&(#%!"'!(()""$$)(""(!&!+")+*(!"&#*)+#*++'##&#+!$$$)")++!'(#*!'&)&)()"+'!('*#!(("!)#!'#'+'!$$&%()*!'*#'$)%$!$%)'*$*(#%(!#'&$'%&*+""#&%&''%'#$#*#'$#(#*#*$+$$)%#$('(%&(&+)"(""+($""''!#*%$(*($)'$!#%%*)%(""#*+!"'"!&$+'"*'&+#&"$+#%!+)'$"#!%&!#))"+%!#(!"$"%%)""''#$')&)#$"$!$'$&(#$%#()"##(%#$$)(##$%$*!)!#)#"$)'!$'#"$"#&%&)%+$#"&)%'*#'(##%&*!%!"&)%&"!+&**($&&)*)&)+"!#*+###&'$%*'#*!%"%&*!%%&+*()&&)!))$&+(!('#"#$#$)#
@r2132
NGCAATNNNNGNGGCNTNNAACNNNTNCNCNATGNCCCNNATNNCTNNNANNNTNNGTGNNNNNNAGAACANNAGTTNTNACNANNNNNGNGTNCCCNCCGGNNGANNTAANCCGTANNATTCNCAATTNANNGNNGANCGTNTCGTNGNGGCAGGCAGANNNGNANCGGNNANNTCANNNANNNNTGCANCNNNNNCTACNNTNGANGNNTCTNANCNANTNNNNNGTNTTTCGNGTCTGNNNCCANTCNNTNGCNCNNTNNANNCTNCNTTTCGCNGNNCCANAATNCCNAGNNNTGNGNGCNTGTGTNNNNNAATCNNNNTGNTNCANNNNCTNCCAGANCCANAANNTNANCATNCNNNAANNNANNNNNNNTNANTNACTCCNGNTGNNNAGCNCCCANNTNNNNNNCTTCTCATATCNNCACNTTCTNCNGANTG
+
!$!!$$"!!$$"$$#!$$!#"#"!$$"$!$#!$$!#"!#$""#$$#$!$$"$$$$##!#!!"!""$#$$##!!$!#$""#""!!#$!!"$"$$#$"$$"!#"!"#!!!##!!""!$!!!"#$""!"!!#""$"$$!$$"!"!#"#$#!"$!$!"#$#$!$!$$#"$#"$#"!"#!$#$"!!#!###!"#!##!##!!#$!$!""###!"""$!"$$#$"$!#$#""!$#"$"$!!$#$"##!#"""#"#!"!#"""#$#!""""!!"!#$!$$$$#!!$"!"#!"$"$$"$###"!"##!#"!$"!!""##!#!""#"$#$!""#"$!!#"""!$#$##$#"#$$$#"$$#!#""$$$$"#"#!$!$!#!!$!!""$$$$"#$$$"#!$$$$#$###$!$#$"$#$#""!!!#!$"""$!$"$!!$$!!$$"$"$"#!"$#
@r2133
AAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTNTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGGAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGA
+
>13B"=<*F81'$HF<">&E#/3F=6/;G'&#8*+D)0G5'#05%<,:5F:E($92D0"88G'#8+%G7HF#(?=D28G#0,&8!$F?*D?BA9&91.<E)C)EF9..=)=F"C2>A@F*+$'$4@H-%77F<&"3&./H*G#85%%.C$B2&>F(0&8/(>#3*:AAD%401@AH(H3646:04$23#/;.!D/C:=3->&?,G38D%9%FD3%&B:F:/%&*-39?'41D=.7.(=D*<96-'D6-27&$?+E!">,"D"*1#B<7!$"1DH4<%;>%!@-D!C.+
@r2134
ACNGTNGGGTNATAAACGGCAAGATGCGGCGTGGCGGTTNTCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGAGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTA
+
%&!%+&&'$+#+$#**%%%'!%")$()*+%("%%&)%!$%(&#+)$(*'#)**!&&+%"*!%&!#$"("!#$!((&"%#+*!*!**''"'!$!'*%+))#%%*(")'$)"$#'%!!+*"+++)(")!'&%*)'")((*'!%*'"%"(!%*+"*&#$*'+
@r2135
TCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGATAACGGGGGCTGAAGCNATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATNGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGNCTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGNGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCTGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGNATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAATTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGACGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGC
+
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
@r2136
GCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTNTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTNTTGTGTTANTGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCNCAATGC
+
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
@r2137
TTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATANCTCTGA
+
*B?DH4GA'E4;7'(E$4390%&3<3#81B0+1)H/?&:0C.<':H<75,7%".!97A!>+8,B#=+D=:$53*H?F?;0-))"E$(G.
@r2138
GCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTNCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGGATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGANCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGANGGCTTTNGCGGCACGGAGCCGCGCAT
+
-#"/3,H-<##C0<B9,$=5$E@"H':D&<.G4(G+!>9,!(6->FG$.H6(?9>:E0$H"=<;@5)*4>5CC.,+A9#C.,D,7&639("#F=*8D%HHE+<84-.!/>,,:D*.*BH9B/,?6(?ED?"650A-$:8/-C6-)9&CA@80#'-.F6.4E/+&<9='.%/=&3B%-#%D45E6;24+/'&G)%->75$,92F='3/)$9H1",G5-,.7#DFA-88$=14<6/"CF"@%=.!1#9!#?<F(:"/G'264>*F=$-)3?<03(H#"C,H=;-?.6?A0B'*GC,69.1#:+3(?;)G1H25=D<(=G&**30'&06BG5E4?C6#466@-938;B/>=$74HA(38"5"E8$;C:GDC#:&<+C:F-)F>7;3$CH&H2=#164(4C76);59"=>64.)?'0@G<(6#51F8*
@r2139
CGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGNCAAAGCTTGAAGGAAATACAAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGG
+
%;(&/<C++1<B?A5A48H44$'A)=C.3E4#9&:?=;?!$=311$5-D27/&33D>8<2.83"C883--+449!/7%C/,(@16H10<$*G.-$9%8*0FE@6DC""CE7GF/E+>!!F,GH(!838-H*8/&%"FC!%2?FF/F,<?(*91
@r2140
CGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAANGCGCCNGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCNCCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGCTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCC
+
>?A5;H9F3>?6*/A+?0531<?'E!4;>8!?(<>1=/=H=6C@<:*/::-G%=":+=4G#-9C?9;''#%1G(6*.;&<D)/$2<=4'3#F@B=>/>C($*72G!9%0."-4'</5(7%9=<C=&H'*-4G/))-&8<#B<>68;&&BH9*"9(C3%+A2+*E3@('-:B?.3-<)-$&.6E-5=C%5A&D&;@.9A7(=68:E("6HG%A&5.<8BD#1*"1<=-:A%(A=A8!+9G=#GG59+'@FB@<==BE@:80,2##7*7)#.18&B48D2@#:<66/GFA&$+<CB:'*GC%A*%/.0B*61(#&,2F6>$$',?4=-/-E*7<=@166+8.%D,&'<8#&&2>2C()E:01C*E&H#G30$+D1/52C&0!=7<9$4D&6.6+B0.=+#63=93=D@F-+,/ED&#D>E+-8,,9=?G/70*EBHB2AE8%@5*A2&5H@(F$)"$;G%8"&+!H$>0D)#7:$)'B95"#CF-)"D?2)D&<HH4,)B8G$3&3%'-H18>$AF5:>D':5A9',@H#&9H4!!=0'"9*DG/-BF8?2,
@r2141
ACACCAAACCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTNCGGAGACTTTGCGATNTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGANACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTNANATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAAT
+
5&<;*7)D30=54!+('G.)55"G:8!='3:-234$@4,5<48C679%(,=;!1B%+5</>"@,/>&<((?41+2,D&H"C1?CG#)!?%@(=AB22/A859:AG))'3HH$F2(>=+4&9.G9)D#"@5G*.:D%#C'"5+&'EE!7$=FA;7HC,>%/"<FG@G3D7*(/,F6!+%369)-/")GE5A7H72FC:,EF'"7$0.E@+4D0GG&A;/H=8D>@AF0%C-"3'3.4"2E61-#+*+(6:&#C%
@r2142
TGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAAGAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGNCGAACTG
+
&CD;574'"H#3"$=617F5B:+(4=)3DF0&(7*;9%3"1"A5?H(!(E;6),</H@4-919@<DD!'&88B56;7C*AA=F%7;'%+->5?:CB.!:=<>".,F,
@r2143
ATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTCCTATCACGTTGTGAACTTCTGAAGTGGTGNTGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCANGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAAGAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTNCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCCGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAGATCCGAAGGCCAGACGGGCACACTGAATCATGGCT
+
83;5*:G(929,35!%7&CB4A-*90E8D3=@/.&'+FD4?6F#5967:00.-0.88@;-+E2H+=>-;C)<;1,?>"3,EF;"<A(4,?B4#7B,*31=>AB*?=A(<C>8.;34--E(76.08C>+9*B,+-$3&304.D',;-A"D21!:<C<5,:7C%+9->('!##,+4:&(57.!8GD*3,2-F!FG7HD%C?*5:@'C<6'#$D=F.!CD"4B/D%-)=&0!B*$9?&'!-&$<!5G'/(>D$5E0<$)A;'4>@3C)7(;=5419<47"6BB0(E$05:+?/5$5A*47H3F,%!A5HGB!34<.==@-3D!:+HA6>F<8E!3;:?+G-2<$$F#323;B<ED7?626*'5A!5CFG2);>?2?C-A"8AH&220(-4"-=0%"55)(8=7(#%F,H?H@@.=:$&4:-%590=":EE68@@!=C-#/$%F4(?=>$*)A?%?!1737.(/;(!<-7).#(H4B?33=;6203F,G
@r2144
NTANTACCNCTCTGTTCCCAGATATTTCGCCGCGACTTTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGNGGCAGCATGACACCGGACATTATCCTTCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGG
+
%&"$%#&&'&)+)&'#"%'"&)#*$"'#(('()(#%+#%&#)%"!!&)*#!$!%*+&%%#$'&'$#'!+$&#)(%"'"%"&((')&*"))*"#*'$&)*!)$"+!')!''"#&(&%"%+!*%#'$)#(&&!%')&+%&+!''+#')"$%+'')'('"")"%''(")($$*%'!")"*(#*!+&
@r2145
TCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGG
+
1=-/-<296-4E#8(7$?8:/3/?G';=<.D&"#5"EFG404C-D+G(:;+E@6(8$6/B-@15,EF,0--CC4H(!5;:>4940./@2E*,@,C4<'2E6*5(0%B9&2:(%5;':01>B!A9+26<"<A2.#$:G"H/=7+A555GHAFEF?"-3!C'!/1;)/#A*!,741;=<H0.84$=EBD;*,B/H$H2BDC27(%@712:;E?:)
@r2146
AATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTTATTCGTGACCTTCTCGACTTCGCCGNACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTT
+
&70069,.7:,*-7(7>0F>.B?+/E"-(89"+G<><+5-<.'41-.'>;B-A)B$5/1<(*7-3#=03(,*21+!0!22AGA4<-?$#!01!A#B>.8!(%/6,?G)-!G!6))'6B'58C7%D
@r2147
NTTTTNGANATTTGATAAAATTAACTGCTTAACTGTCAATGTAATAC
+
!%'$$!!*'*!%%+)*%*$!(*$%%!+%+"!!)$'*!&%%!&&#(&#
@r2148
GATGGCCAGAGTCAGGCGTCATTTTTCTGGTANNGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGNCGGGCAAAGTCCGTGGCTGATCCTGCTGCAANAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGCTCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCNGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATT
+
E.0%)&($DD=E>./07G79G42F-E'>)B0=7@&=")#$%5B>;!GDG58'"3C;+5,++'$>A+<(,*/D(?3!2D!B&(.?$!,5#==F4;815F#1<F!66+-<A/*G:*9%&F.%71E(37C/&3/6'?6%?/:<H)+<5D'"?<@H-(!8:C7*-C=:8D3*./-@@7D:@#<@531B9.306+,5-E/0:'H!</7"62@>?31?2+G4://%CF>F.-E3;5.$=E<8F-!3?AB=0;0(B%)3>3>=;&>.H+#0#'0B2)BB5G*85>/<7(.#CA"6;.41(@8<4&EA?B08*9G?,<?=HB7:#&CHA/?/8&.H#+"/A,?#*$GAD7?'(9AH+H8G+?"<H%%A;"9%E8:*)D@=&=7<6G@5
@r2149
CTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACANGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGA
+
BD00'6)BC1A3HE.')(@<E,&/*4;$ECG7.#50:9=5DC9H#/+";!1"1>&5:")G-''GE@778&H9@4*%$!?4D(1$A.>0%EF7,HE;7+'78"*E5)CC?%:=A/198@=8-8CC=+B9&,&/6';C8@1-5-#+25'&'E;728,(4/2#@0/&$.6*<B%!?8G>(H#A809F&(0<=35(8,@&(B/)E10@<%C3%:".:2E27$,)E;G9*0@A2,C2E@#?1F5&DGH;@81+3/>DH?@.CH,#39!89>G;*?BFG&5;F1>F#//!E?B/$%;?)9)B!&72B7EF-)%9>8F5-D0?2".A$(''.8%A1!+"9$$$0#D@7;-3A1"&4*5C"9!=*2C;;A;B&6$"5=9?4+6D#8/=2>?F0>2"4$F.!/1>;D8!@,$>8#C*27;;/"FB6EHC?",$G?$,?1/--*,<*"A43>29=75+5'D.%7$+4%9.CF&@:229G5BC
@r2150
GGCNTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTC
+
752!;!5BAAC'1F*%$:<1,BF<9%2(<GH?@"76&D).C.<>79;B<H-/4HA&5(FB6.7/D:(!D,/->A&5(5?5032+D53D4H&<,02#E78-#FG6%*?:(%:?F/4>!C6>3F%%">)7+=$6(/&B
@r2151
AATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACANTAGGGAAACTGCGTGTTGAGCTTGAAANAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTNANCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTTCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGA
+
F?&?.<>$'(0(/&B#C>4'"(?-!%2?24DF?A:30B,"E:-5-+#C=1%64"+9*:;6418&1"E65+3!0<.5C>%=6@@/E$%9.C#,?:=7D%#@0(H*($@F>@/3D.%E(B+*$7+>D%/7(=?9:9'>9F:,8,D%96A+F4,1>#*1!=->9?G8F4$'!(B?%9-+?8-5F<9A"1!+,;H1-23;G!E?/72F+-'.;+'1.$9@1?,/.E=G)73"H9(!44G)(EAFH0&&)01,)5?10&-&%;G46&E7.98G.:,(D2FC$#4-0:/1%?'G&8-8?2!;&#A14/0-"39#8?E%$8)(&1;64?1%;01C3)</<+:#G4AH&14"0=6"12B=0F&:-344%864,@B+%$68D@7!1H)*&!=-194$<,%H%H44@1+2'3;<9C:?30.:8$:6%GD68%'03>)EA<-5/;(@?E;=)21%3$1?@0&#&'85
@r2152
CCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGTGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCNGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGNGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCNCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATTAGCGGCTCATTAAAGGCCATGCTGNCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGGCGCAGCCCGGATTCAAATGCTGCNGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTNTCNCGGACCTGCTGGGCAAAAANTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTAGGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGANCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCNATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCNTCATCTGCTCCATCACGCTGTAANACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGNGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGNCCATTTCTGCGCCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCNGTTCCGGCTGTCGCCGGTATTGTTC
+
A#(F%%(2:#)57G%)8E;6'27(!6%9E*,:=8;=":A08,*@D7'%./EH1+AB&1.0/<+%C''*)&E)-G3&C;FG!(1%F<C*!("-04,8/')9:)'F*!5?+FFB!4H?"6)'0==H6&$2A'!)?3G3<E*><)BC.*3H59FF"B-(5*B,#GH?DE*C1%E?6)38=/A;@>1$A>3:HA88$3:$&361&H@F@+!!#-8.B:B4@(4!+&6:$*E?56>&<!)0>8(8<&0H1:,D;+E&3E"#?%:4/BD'.9*@9/8;7H5!H'2:#A!*3G5HE$=."DB/=#CG(0CA64=G%(.!H8H:.3'*'8.@F$G!:#0%&91F6##?6+)<4CB)A2-9%CF2=7@9@5B23(5">/!5/@==,D%2DD!(,>)@H%3A-D/#=0'=>A7<2:)?6D//8-D/@:<4H1,2&?86+%627B1+7!.D><+DH:-(EC8:A$&<,E!?,-;9E97DDA9/<#<!*>"5H%'@AH>-C?0'C>),"):"+)0-7:-9G+D'4+-A.8'"%(&5A?-7H5>199!&"7$!5F"#28<29-E%!>?"9?-G00%)2BHF897">604CE#<'#&>$0*!!(E*81&5*A5@E)<G8F1$<0$')A@!>,/<@/H'52-=%4%:(C<"(#)%6,8";-@7;2-B)"@F<&6!&&75D118=B"1*+"?&>B8G/E495G0G9+F(@C#)==GAGC?G<3E375D'-'-:=GB7"%!,041#++'AF99&/C0)5'"&E6(9<!?A.-)6FB<9'2D5>.7(6@BG4=<>&95>H?)!>3C7#D.6H<989$$?&55*:0F.9+6'?4E&9+)1GD1A#G!A=@CD)1)098?/5-7G2:&@$;.'@6@$920>G;7?@BA%9.C2;@&*).+:=<EE!!!=-62(/=',B,ACF'&6&5&=,$*/0C&/63-*?-G2HB>/>#1"(.=A'4=;6,6+F08FB7'=/=$?$F8?:$?CE8@;9.+10%HB"?13;+H1G9.%H=(E444&H2A"6>/&B'23B+%,@?4($8""(++.&#;@388)7"1$;7E#">D"1:&4E0E4%;::;8G&&':G)31%D:=5408C;+#F>0B'&&,9#&!H2'8@HA;F3%*-*CH-8,03*.:=))*8+&25./;G8@)0&$/H)+$3++F(+2/+H9:G(.;C+?/3@6004(A>03+!6B"7/:.H"H1!.?8;(/,8.&,(,@$=11@4A7%:A$?!&76C40F)?1A;;#F&B,(5?=$,/0.-7&**2-9?==857*.-=9?9B/%<9'+$C#>@5'981,!6:47H/+%E*4;>&5GFC99C-C7&8!D'%69)#AD+4;963+%%"0#8!=#3,2-<433?#!>E;9()1/@#,D,*/02D0&G96G>"$),20$F$);'2&79E9&G)',.*F346>(79)=6,5%G;C=DGF:1?1)0!/C185=:(H&';9:&,/62C@*<'"2?G@%*A>954>
@r2153
TATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCG
+
+)!#!%#'))+'$)'%*'"%"(""*(#)%"#)''!(####*'(
@r2154
TNGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAANAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTNCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAA
+
'&1!,6/))E.>:+:F%301#@+E22:GB(35;$2.;E=4.;H$)$7G/<C$56!EFEB$'CH!4;&A()4/C-$&!*2E;,0>&(.?6%4$&H,3F0G0"":FE)6-.-E/4/C)4F1+;5<"HE2B=+HE9#DDF"F?B"!#/D5C9E,";2136
@r2155
GCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGTCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTNCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGNCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGNCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCGGCTGCTTTTTGTTGACTTCCATTGTTCATNCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGT
+
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
@r2156
GGCATAANATGCAGTGGACGCCAGAAAATTAAGGGAAAANCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATNCAGTCCAGTAANTATCCTCAATAGNGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACCCACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCNGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTAGCATCTTAATG
+
,@;$*G/#%()>7%H<9.-$6HF8--C*,*2*0<'86$42*2==89!11'+",:3)&8!&AG7=9<&>A*14G%$7DF/=.4'37#2!4H1)7HH<C0''9,B#*&#20D#@>/*EC815';G+G)GD?1AA9'9%A#A$=*'44)DFGF!-))H<DG(!:F#?G<G>&6H6G4.DG/"6>?GA=5-/3A&$/E1D=A&(&5;'?;GB*4)@:/26'7#B9$@=+.'!."BD8D*&-BFC69#'$03-%D'2>E<%&1/(+(7=@@;+B9?E#>D%5*;&/DD3#E/4H=A&7'$B1-2!"1=;C-1.8D*C&#B9-8#7%'GD;/A#4D:F!<$3',7(>.&
@r2157
TACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGAC
+
D%2H>A4!'G;*25$)1)BG*&CAF6G9C*8*0)$(HA@:3(CB(8)5-?$)>/&A5<!4F<'5;%
@r2158
CACGGTGAATGGTGTCACGCCGACAGCGGTGCAGCACCTGACCGCAGAAG
+
<-2C@$3:B3B2?B9(<0:.!&B!##+.)')-)F"'F=%4452)H@42A)
@r2159
CGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACNCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCT
+
FF16,CAH2/'D@7#<?.1(,5.GE*'C*?E%9+0G53&>*:,?-%'B+&?/:.G<8=F)80/@*?E?"*E8-4@/@1-8;%&$8"F4A?55H5F+<@"D06)<,2C/47*$580@7'F(!$A?G.$4-:"!>.*,,@(.<-H(*9:+FC.*+<:-47>1;)0*-99-4B,5;"A7
@r2160
TATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGNTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGA
+
95%B'-5;>63%#*!.&/>+9E!HHB5D?2%?7$:5%D>1(,=<!,<*-A(/;0E8G(:-8GEF9>4G<D>-"G-A!".&71;.&'(*:%::CF0/@?H6/)!60=H()"/(:G&>(H:9758@!;-/3B-+5!F9E00E'=B%&@+7A:*:3/9E&1@5):':DG<GA=+C+?6.<#H-
@r2161
NTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGC
+
$=429#4'+42-A?40?,1-F.<9%C1C8"@)"F(7/C4303BF"55/5$G0*=*<>G?)-9@8
@r2162
TTTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGNTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGCTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGAGGCGTTGCAGGCGTCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGNGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCCCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCCCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGACTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACNAGGCACTGAANGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAANCAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAANTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGNAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGACTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGC
+
)!+&"($%++"$)()""%%((%$&(%$#!%$%%#&$!()%#)"!'((*%(')(%"')##%+!%'%#'%($)+'+(#)$#'*")("**$!%&+*++++%"$%*!!(&)$!#$'##(##""'((%''%*(+"#")$()')!*'%(!+")+#%+$)##+("##(!&$%'+%(%'$'+)"!%!''&&(&)&##$*%&&#&"(('()!*!!%'''!""#!*%"&"#'")$$#"%)#'$(#+!&+#'%!(++%##)$(*!!$'&'*+&$)*+')#("*%+)+$!%!%+%()"&(+%+"*#**(*!%'%%"%%$%#$*%*$'**!&(&+&&"+&&(&)&+!!)($'+$*+%"$*(#&"'#"+(*)'##''*!#"*$!&"$!"#!)"(((+$('"+%#*!$+!""&%$'+&!%+**$'((()*&*(""+%&()'"($'(("$!+%*'!%&#)#(#)$&&$'%&&(!+)&*+($%(&"%#$$*+%$)%&*+&#$$+"$"'+'*&(%#)#&!(*%'!$!))"%(%&'!+!)+$))"&'*$&+%%%"#!**%'&$*'$'"#+'+)+(!'("(('"'!%*('$$"$#&()("#+!&#)*&'+#)"(+!&#'(&)&+%"""$%*!)+(#()%(&%%#)"($'%&*+)&#"'*&''+*%!(&'("#$&$#+!!"&$!!)()("%)+$&*$$''%!%%!+)&+%+%&)#*!(')%)"'*$$+#&!&%!$+&')#*"'!)%&$+((""'!+)*+'((#(*'$#(%'%'"+!'%"'&%"!"#%+)$'$$#!'#()""#*#!!+#&&%'!'#+&!""&(+(("("$'!&%!$+(&#"!(&!""!"+*"!*"%+(('*(*'*$)'!!'+%*%(&&%+&'$(!()')+)(+'%*&"&'!%%(#$+*'**)#!+#*+*'(%#+#("($')()$*(&#((#(#*##%'%((*&+!#%!)(*+%)#+%+!('%%*&*))%#&*+*(++(*!#(%'$%%!&##(++&$'#(#$&&"&''%%%&'!)$+'"!###+'($$!%)$#"(#+#&*$*""'*)
@r2163
GACGATGGCCACATCGCCATACATCCCCTTATNGGCCACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTA
+
/B*(8'?A7@*1@B.HC;>'4<7>97:#'9>;.$@G0*;DB2C.9<*=G5"20>)>@*-4.:D"F-%=A:H94=/H6<BDE#
@r2164
GTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCANGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCGTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAANTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTNGAATGTTGGTTACGNCTGCACGTGCTATNTGCGCNCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTNCATTCTCCTGTGACTCGNAAGTGCATTTATCATCTCCATAAAATNAAACCCGCCGTAGNGAGTTCAGATAAAATAAANCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAANAATTTTGNACGGTATCAGTCATTTCTCGCACATTGCAGAGTGGGGATTTGTCTTCATGAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACNAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTTAGACTCTNACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTANACGGTNTCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCAT
+
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
@r2165
NGAAGTGCGGTNTCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGNCAANACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGANTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAACGAACTGGCCGC
+
$':A3/#,A>F(-H?++F-<H0>7*#@82??23%*"%8,DHE*7#<0<?E60@9;!2/10:=)'@9302@/;9CC<'86780&@;);D)9/24CHD7=*D?"*FG)3=/5E@D%$)'B,58!:7CD8C#'9G8!4"64)&H6*/4=&C&%;A'477@.F&0C"H0..;$-3-*?8"1+:8E+F7A@-.0.<"<.@@0$78#!7>H:*6&%3E>@$E%(H#,+4B2,<BF:'@)G*8D;&FECH+H-8@"$>A>D"9$>)"78):7,1-<4?CC4*18*15;5'7(*7%7=!BB-*9<143%,59&?D-%7F,?.;7;"9#/+/>E+@&(HG/EA:*CD5F'=+E8-1!5HD2,C6=A(5D43:/23:;H+A41,30;)",!-7%B8C93F9*",
@r2166
TACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATNTACTATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCNTGTTATGCCGCGTTCGCCAGGCTTGGTGTACCATGTGCGCTGATTCTTGCGCTCAATACGT
+
3F>(<.%513*35/(<2'G2**7'"H?(&"-)&!.*>+&5A384<686E<"F@F-4@>7=54418)4&89=62;?E;=D"E<57C2.*0?':>5)'AHB;;/&;236E5):/F"B?42#C,'AE/5-%G.B5!D"E>GB53"!61;'"A)D"'&?7;>G;$9F5.)6&-@H$,B761&.;</H""@:),$-%&-8(.(@/>.&?3+H%.('@&:G<BCHDC6(-/&@H.6=+,0'".+:8?(,-&-2@;09)!?BE?*3?1#@G,A;.&7C9#2*7*4:-<71D31=.G7
@r2167
CTGTTACTGGTCGATTTAAGTCANCCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACACAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGNTACGTCTGCATGTGCTATCTGCGCCCATATNATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGNGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCT
+
6-(/:=@C@4.<",=.B'D&%)4H5@DC4$)*";),#%+E%3'D;)(%+;('B""E*+#37!8!?.!36,;2#5,:1E:96D*%-;!%!*@$9A+/3+1#8H93:%(=*?'22&">?<D$H$A-.GB<!3)B#)>=?>#6=,9!E*1-%H%EE-=B((.A1..(0>&)5-+*<&'@/B>1#3<1''"((GGE*2?><9(%*%HBB-E-?A!909=-;-81;;/AC/3,G8'8%%A:2&*=AD!?$9"*=A+.@44A%,+3$16:@H(7C7%%5$;,+&:2"&<$@,"F=8/A?G**3*+D:,G8):-C5F'-9A=&&#56'E'.13#&"%+A!!=CG67*%C.D5<<83)<11<43F22*6C30F?3@&>@2E>.HC"*F'>$4HB)C8@/7A575F'H08E+&=?H+<1*$H$08EA+-214<4H7G)>$5H
@r2168
TTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCT
+
.4=AB#D<53BFFB-,#H!<F;AC"@'1?).)6/:!.64+D-F44F9#8.5"*E2H;ACH"6/A0A;1?..?
@r2169
CGAGATAAAAACAAACCCGCTAGAACATATTACGATGACNTGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGNCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGCTTCATCCCTATATCGACAAGGACATTTTTTTT
+
'3!51A<!<@924!/)/;-14196"*9!AG0(#52CA@(9.G!FC3=A++1><C888@F)DF:70>9!F60.8C#(G5(3+G1B0@!C#!51B-@677;+(D<E23"=$B68G/#-/97G4/CE*E*7<>!,,-7:*->;/D!G;(,);8*+03<F(*:0&G>?,9H3>/E$G,;$;0@0236(F29?F$8>>G5$/"*1=94"-A7-1<2,D0G-0=C2<?@DG07@D=,@)4BA=HHB$/"84A3@#35(&,+4(H2'-4.*
@r2170
NGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGC
+
$&''(>H=',.H231D&/A-=F>BD;*:3CG<&1/:0#+<'5.E+G&!1?-9.%@E*@(H;G,&9HC.;@=6B("F.9(.:F&F8;/HE0.>+7?.1.))D7.F!@D4D-*.*D2%C"9!-%@%!$?9;A<.G-B"+8:3A//;48:+*?$,>:?B'=-9*D3,;2"&H;B,9'4D+6$#A,AE:">'1*+@&8$'3%2@F40;68'(*D$0++D'12:A3<%B5C"2%"%A,#@12>C4B06C476<E&#3+44)<D68+0H1FA0FBH687F?-/8A.6FDC%5/4E0>1='%/1A/GF8>=$(+2;/<)0H4955B<E$C,B<<0(H4=;?%"9110##C!5C5:=6<:,BCE:8C4/=G49G)9+:#.-)FB3(7)&@2(A#F+BF)0F!F9
@r2171
CAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACCCGTGGTTTCTCAGGAGATCAGCACGNCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACGCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCANCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTANAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCT
+
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
@r2172
GACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGT
+
6-+22.:H?1@764HA4);%?H.%)+B$##F";E143$*?49<D>>A592*>?C?))D9,
@r2173
NATGGAATGATTGGTGCAATCACCAACCCAGAAAACCATGAATATTTTTTCTNTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATNGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACATAATACTTT
+
"5*(-/5$&)E<BE;H<.9?;4/.1C*:$-?+@?$>79E:C@1D:;*D/=)85/F(E+;F+F5#8A#B)1>)?2*FD3.+'%%D.,62B4%>CH2G;E-F8)B)306&5-,EG-@2D8$+==G(?(-.4$5'E7?H?:'61G88"F$H/)13"(G$07((1A>7:2;?"86$A,=+E.-,E<($9)/GG
@r2174
CAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTA
+
F).?E?G-G(C05.CA#D4=B7@E>A;,+<#"B5ABC$=CG15C&=G>
@r2175
ACACGCCGATCACCCGCACCATTACGTCTGCAAACATTGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAANGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTNAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACAGCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTTAAATCATCGATGTGAAACAGTACTACCCGAACACGGCACTTGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGNAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTATGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATNGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGC
+
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
@r2176
GGANCTNCGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCNTGCGTATCTTCAACAA
+
$'&%#&!'+)#)++*#($($('#%&(+")*$%"#'$%$$&)$&&!')%!*$#"%+&'*((*$!!%!)#++"$''%#('"")(#+%!%!$+*")+$
@r2177
GCGGCAGTTAATCGAACAAAACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGG
+
@5C:.5.'=B+H+/'G==5/BHB;9D7!;.BG5)D!.*3CD)A:+D&4;<794?AF,&52&/C
@r2178
NGGCNNGGCATACCGGAGGTGTCCGCTTTGNCCCGGACGGGAATG
+
#'(%$$)&""%#!+("*&!%!&*+'!(##&'"'&&*+#)$*"+#)
@r2179
GTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCCATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTNTGTTCCCCTGAGCGCGGNTGGTGCTGTTGGCGTTCCGGTCANTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCTTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGGANCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCNGCNTCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCANCCTCTGTCGCCTTCGTGGATGCCGTTCACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATG
+
@32/'&)*>$1C0%,)(H97A:%'02.0570>5()@/!>)-6?=#DB@G9@-@,/0<$EAH%>*E#,'&HGH-&G4*A@D5D/6!)F=2-C/A$-37'5A?@9@:15D3B>+8'&+28?71>(DA*)%=#""9F.%&(D%33/@+DC7D,;!>1+.B)@;+<*,8&(@#F-F6H/)4C()G7$'&;=,/2B%<$9>AGA#4<E':E#:C(C)8>C9":CHF;C1H<,-#$D(BE3A%)3=5*:<3+.=.(D*45E75'C&1D"G7C.6HBHD-/D9%A/D(.BH6:0(?B1*=1$7<G.DF#3.$18"A7@C5")D+F2=&"#C-FB9;;8?D$#<*2&'*;@H*B104).)46@H2?&2H')@(8-A.C<BBF9)64@=7H3;F%7+F822,B+:5/"$(<BCC=,/>536H@+G(.D4=&=F$7.7+E7C<;4A4A;&&GF<#8A3+*;.43C@C1.B=+;1-&8:*=2)2B*%0?*H>212)1.=$2)$A9@&0D%>8G:'3D#)*GG7+FB%>>711$7H.-&$!>(GF<=3"G/1:>=?>7<(20)(>,+8&9#?8'#A;.4/,>BD>#*
@r2180
GCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAG
+
G:-AE<<'404=)+16,@'%E45=H%*<$!/*1;AF;("18*)F7
@r2181
CGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTNTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAACTATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAANGACTTCCCCAATTATTGGAAAAGAG
+
94+<6$*++<<?H1;H<?G@76,;9CE&:?H&(C2A%"<'G4HE=;99;(->=&?;"!"<5#::=6*BG6<!5%7?(63152;5D==!#D!8<(06)G!?#D3.4C"=8?FE(@2C6+0%"%$:3=*F(C=$%36;:8(-F554&FH(D.HB20:<D0.62?E$;?76)G<-%4+>$!8,<16/3@*!=HE2>H%7,F#F!3-%B1>6A7'*@1;DC5*97@%3H,G="1:4$?H8*G&!@'F37'%%5)5'$H="(H1:D,@(-%488(7'6F7<<")7.5C<-6%6?<$?@<.F9'=<4;@*&?7%-D+'?#:C>"B%D29(-B26'896&:C%13E=:?3*<)F(!(5&F:E9%#)6E/E0().#E;F2%H%?#9$;'#0')-<-$>G508/;>:/:)1;<@-*,<D70)G(*7
@r2182
CGATTGACTCTTCTGTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGANTAGCATCGTCACAGCGCNATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTNGGCAATATCAACCGCACGGCCTGTACCATGGNAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGNAATAATCCGCATAAGCGNATGTTGCGAGCACTTGCAGTACNTTTGCCTTAGTATTTNCTTCAAGCTTTGCCACACCACGGTATTTCGCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGCTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCACCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTC
+
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
@r2183
AACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGANGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGGGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATC
+
%AH@:@:#,:*F9B6A8<$&1HB<9B.@)@=;E*-1($2+==B>@FE&0!&%5&06D/E&G/D(H7%'67/4':+57E3.3.!,'/!EC;<169!-':;<F:2F&=!E1<8@<6<E,D;4'+G=-35E(CD$B.!6)$B(=<@F-
@r2184
CAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCAACACGGGNAGACTTCACCACATTCACCTCACGG
+
.1(F&<"**--$#!%:,>"#%@+E2/%8!!6*6-4)1@C;4&$"DD?;8"&E1B<>1"5,>9))&G7/BH(4&>=B4<1%'0(>4-$9>!<%/HHCD;(GE%"A&6:C0.1;5G<+"$?@$A<*A+:199,0.,)(6'/6%.AA3E:+!;?9E2H&2C>8&%(2H/58!CFC-&6&B-62%?!:0!E)<:H"7(0157.0/)023#.E@(.D'FH8'6=0+*6F'-))(6$9@,=6-;*(/25?%)++8<*@.A">%1@<6476A#F;80@"7C>6A";6+EG-8@@#>0$!'!-0$1?)8E8+<$?70D/).3@6H@.01,/-%C)*C*&<'=C
@r2185
TTAAGGAAAACAGACAGGTTTATTGNGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCAAAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTNCTGNGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCNTGCTCNATTGTTATCAGCTATNCGCCGACCAGAACACNTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGNTAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTNCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGNAGANATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCGGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTN
+
!)+'&%)')%"'%"'(&+#&"%#))+$'((*&$+')+++*$*''*!!#"&'*$"+#'%+)$(+#'($!"$!+&#'"$+)('!!(!&(+&"+'(""&+&&&!)$+*++""*#$!(!)**&!("&$%%+(!$&#'*'($!)%%(!!$)$&)(+!++&#%)(")*#&%+#'#))"&&%##'*%"%")*#)!)*&)(&!+()(''"&+"+*%)(*%)'$&"+"$'"!"$(%"%'$!%'$*++"!""+(&)+%)*$+("$+%*$!#()%)"#$!(*&""'#!())#)'!)#+)#'$!"*#!)!"+$!&)((!+!''))+**'"&*'')#"!#!)#((!$'!%+!&(+&)'#'"%%**'+"%)**)*"&!*(+!!##())*)($$(%**&*+&"&%!#(!!%*)%""&$*(&)"!$'%"*'$&$%*"%*"&!%+"#*$%&!+$()"'(*)()'$$"((&((+')$"*&*(+#)&+#(&&"$#"$)(()$!+&('"&")*!+'"$!%$"'"&())#)'*()(%(%+*+*
@r2186
CCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCATTCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACANAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGNCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTT
+
"H@2-6+*>-2F$=<9#:F+>#$4H:$.82-H%?<)2".B%>D>F$*#7%&%#0#H!&#@;G@9)9?#B#.8/,H&="C.+?B!C?;*@"%&A;)!1(95#2C-D2@E0=;4H49%?19/!.+AF$"03@F0-7=*AGA:=*CB'$1)?#$(9H%1)#816DE%84<1H6&88--04?$9C(D17&.7'A$D@(@CE8&/44<.=8)2-,*'(;#@1@E7!=.$@:)!0/E)7A.&F#E%++FB=-485G0-%>;!31<5FB;1G(6FBAH$>?(27F$'F'<#BF,)*#>9&&H5>540"'$&91F"!HCC?9"&20E>3C+39A;D.2C'=84!A>B-H":?760:-#!8&!7#7%C-%$#4BG%(#<@=)=9#F-F./:$)!"<"F"/24&(H;-+;5CG7D/8&+<+*=7>7>/,B68;2'H/=D/!F;7AG&.$,9C2056>':>>BG00&H&C0$&&DD?16=$!$A8?7#*=D/"G8.B-6&D6ED5B@8BD&A2-8<&9E$&$5+B4,#8?FA$%&+#A1>%&.C($G03=</C7$9-&)'-<&&'>A;4-G!.9>8<E!!D6G-:;(7#C/?'!6=2/C+8249@40H8--)*4$&!$C
@r2187
TAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTT
+
=3E##12$G"2<$'?,?;3-H.?.A#@>BF>EE1%D;C.562F"D"==01/'A(82HB!CECB!"AAF:263@-1(.69!C-B,:D(+F1;9+=$6B&68,*6:0#(;?H)2+%?&61/5;,57"&:D1H+.D*)-66;-
@r2188
TTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAANCGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTNCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGNGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATC
+
=(2BC;)>>6:.++>+.F%587(A";6/>&.5+=4#''#&-*6C(3+:;D7(C9-B$EG,';?=D4/(=2=+$8<='&70<,=HG&6D5(0)EB8'65+(*">$***/55&C4@&HB)4A@1#!9&5?2%#F-3'A&29/8.#@*GDC+!5E-'#F!;740;H=!(B'A62)B(A!@E?GA,.)!>,99:A#99:A0/=!!&F.H!A@"(9',>#AH&B,?4&:@"=@H/.&4<(!''6*6;$*%3-E<=B/C9966.#H'B)*'?B.+921&C9E%%D+G@4,F3-*%=.<191.(844$9
@r2189
TGCTGCNTGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTG
+
'5A0-5:(>2@6-0"17%*4(;)13*#%<,2)?B-2:6,@#"B&$/+6#"E0,(#A&,!;$=21#&>31$6G<GE!=*,:@?$&17.H-&F71E(/0*F>BA,.;-G.,C,6*06=$1276F53
@r2190
AAAAGCAGAAGTCCAACCCCGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATNCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATNCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGNCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAANAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATNCCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCNATGGATGCAAGCTGCAATNGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAANCAGAACAACTAAGCTGCCTGANAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGNCGCTCGTAACTAAACAG
+
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
@r2191
GCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCNGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACT
+
/8/4>)@C,A605&GG#60H3%.H-9(;"@3&#-'%;"%,6>;D97F%'61:C%?GA;=:B?5A4F($);?6E3<:GF95A:34@C')3B;86H.-#=$-?#.!16-;$?)?3B!08;.*C?'2'1;#;/4#B>G;?1;:&440(/D19@+:-%&<2>47&70:&4!?&)@./"A!="B>D#HE#-&:)B1@FC$/+F8@2(4C!(-"-FA#>7E(7?>:4)H.4:B;G8&GFH#C.1,7%1,.*!HFG056G3?+9%#9/=$789A1$H,G/8-0?21EDA4%(F+75/-93:$-:H/%(/@?<C=7*(*!3E!B-,?1F>A-A#;'D19<AA6#D+@,587,7F18("D#HH;B+<5--=;@93((*<5
@r2192
ANACNAGNAAAANGCGTAGNNGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCAGCA
+
)#'#!&#!"%%&)*#*&))!!+"%'###!&"!$!&"%%''')$!++&##!&#+&#"*+'%&(#!)!'%"$!'(%&#&$"&'&&$+!$*#&
@r2193
TACCGAGNTGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCNAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGAGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTATTCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATANATGGCTTCAG
+
@>!3B0.5%=(%!G6&"!8+)/1A<1)'7-<B5?>5;.:6<>!'3'%2"9DC*3&&=$A8D@'@%B/9G"('8D-#>+'&=C96(@1#$,8H"?A319:$8D3B-#HG+!8/>-&A@/(5<7D8--*9B2,6?5%?>6#!H*/&:ECH#:!9@"<E(&G+?220F&6%/0;".<!F4C9>!8.G+)=393B?#C=589-C&+')?$8!*2)FG37#%E8=%3#:BDE3HE8G%":5<()'!'?4125,67G$8H&&#H4F=%.E@;84#&)%&&D+?@E//C86E?
@r2194
CGANTCCGACTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCCGNACCGGAAAGAGAGTCAGAAGCCGTGNCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCAC
+
<1.37D(%82:+;B+83&C0,0;$1G$H2;2/4C9:*?=H)0F#,"A69*-@*=59D@5E$6/54//6A;35B+:2+94,D6G/,!'%9=50D.%2:;(0*#2=D?28B7'%:D3+D/G?676$=%A0@:3854-A2F;'/=2+B6;BA&.<-D+%">8,26F4112A+>5"1?B#E.D.5&/(G7>)"*+0;HG#+$"G/@"7-45%G"+/C0?9(.3951&+A#F*G$/3+E0?6
@r2195
GTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCCCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAG
+
+!#'$"$"#'%#&)*$(+%+%)%!#++'+&&))"&'#'!)"'%%"+!))'(#%+"!)!(+(+!+'(*'(*&+!*""#*)$(**#*!$%)'**+"'*#(#)$*)!"(*)$+)&$$+*$&"#()''"#!'&*)'+))$)&&*("
@r2196
TGCGGCCAGAANGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAC
+
%F",<!,DF=?4HA$<&5DF)7-%86&$?".#:C%<A6>6%BC(H-/'<H%"6.8:%
@r2197
NCCCAGCGCCGCACCGCTGTNATTAATCTGCACACCGGCACGGCCGTTCCGGNTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGCATCCCAGGTGGCCTGNACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGNAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGA
+
"@()5%16AF#G!D"$)?6*,*6@=H*#-=%A%B7>7B07*'468GCB7,G('<B>+;(C-25<-*11<4@@<!("H6*8))"0>(E-*7$(+='1C(A03HA#GA)!G-#@..;"*1F''7&4F-59(;<2,*;5"C?B:CH49&E=!'75&"<-;!!GD;18;HA8;FDF25/:#-!,<&&%!H?&'!)-1A+=AEDBG*@..'.#>:C.0+EDC?>7@>@<#>#<F,=A.E$AA3"A,;@3#':++<E;GH(FE0$C8((96'81-!="(%7=HG#%52!=F9%-G+DF5&":"A#6&5H6#G)&1%G-B2BCB-H@'A)G%/8"0;30B3(@6%64/CF*9@>.C'F#D/-!C10&%'%!-
@r2198
TCGTGGTTTAATGAAGGCGATACCCGTCCCTATAAAATCCGCTTCCCGAANGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTNATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACANCGGCAACCGGCATGACCGTGACGCCTGCCAGNACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCAGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATTACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGNGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTANACAGAATGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTANGTATGAGTTTGTGGTGAATCATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGC
+
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
@r2199
ACGAATCAGATCCACGGAGGGATCATCANCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTGAAATATTACTTCAA
+
%;FG">.+2"4+:;')A8A)+"=9CFC493!53CE8&#A#.;4>'%>79&B/7+)C1'C(58D51%HC"@)C3<E/FB.>.AF&8>:!*0H-'810'CFB
@r2200
TTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAANGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCNGCCACCGGAGAAATTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCNACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCNTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAG
+
$4$*D@BBC2-7(.*C/12GE&@:">GB;%E)!&A#GB+G%57:;(-H>'B556"1>F?*8794%(/62/AE27);!#(16':6*:?-$-.-.4*7%*?@5D*-/C04&6=#)"E&@H"5H,"4%E#H-C%67/<4"#1E7HD>=D8H.,7-E-D04+6%3&E<@H-@2=F>:)*!C%0G<GD,+(-;:(,8?+9=DB2*A@*$CD4C$6D%;;5$!(DAE&@'*!.C+(<"B/#-%&:$CA-3+E+*/G04<4AD52E#1?>3A'1("::+2G9F5>2;B;B1638DA-#9$<!3B>,4#%(8;+%*A/)$..3H19+7-:@?0-E<?'$HH0).?19B""!,8A*;/&8&?+%?6@,+,,#B#86H%<$>*>B'6!E<-=<C6-B%C4"#GB03.&)*084=B%<6*,:=+%E4C9>'.(*:CD,5GAC10;3H;0%H
@r2201
CACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGA
+
'38C(F*(4'-+="+!H,"81D<7"A?.?G*.)2:E&G$3B9/7@B:!>B*FH.A8@+?7+:16@?+83,%$=A/&0G8=A4D,(<A0-4-&2'H.*;6B<81;!)1<-*0F6'%$!B5#0B6>D"#&G8:D$5:?=,*,@(>-*8463$B'!<$9H,<:D<(5B&;#1>33#<4C!+(#"
@r2202
CGGCGGCCACCAGTGCCGGTGCGGCGGAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCANCCGCCACGTCT
+
@/8.B;H5D8!'E3?)C-.%?+&1'&.C!6;6<5H'9,*B;2A</!FHB<<2$7A/!A)8(8H%+?FG/"$@A055"
@r2203
ANAACNTTTTTAAGNTNTATNANTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAA
+
%"#&"'*&*(%$&#*"!%!(*)+#+%*$%&&*(%)(#%"#((&!'#%%'%"#(*&*$$&!&%!"#'#)'!$#'%$("#"!%*#(!%%'#*""&+()$'##($+'%&#*'$''#!)*%#!'%!
@r2204
GGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGANANGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATTTGGTCGTTGATTTGNGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCNTCA
+
?5!()>&DF9029:*;#')==8HD.';6/7H#+4C03:1ED1D6D*-9B<G/1=0=E93>#C*7D:770*81%(/$66F)E=:24G(6.&172"+7;).C8$%B@6!::2>00;CG5B65!*@589=(8*DA<H82G'1%G,-D?HB?3-CE$&%A/80+%?=>$.,E<)+7&B3/GD?&<&"78:9@C/(@0&()9.A=8#-+H-.
@r2205
CTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTT
+
!>55:E!A.>E/5EA5;CH%&6F!?;D2>79<ABG(?"?CG2;F&"47D2A2=HGH(7+/FD/&717#6:3$$?=0%5(>2!;?.7)1D%&D$E#>.$>6FF8D0.+>C&"G0$@50.>9E*FF,7GF0*1;'/:2D9!!@*>9+A!6F9#2HC.:G$);
@r2206
AACCCACAGTACCCAATGATCCCATGTAATGAGAGTTGTTCCGTNGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCNTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTATATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAANCTGTCTGTTTTCCTTAATTCTCTGCTGGCNGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAANNCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAANC
+
()02"-'.*697H#,12327&G$&G=:339=";5%&#7:19?>=*-*"64-*4+99=&"H@6#<0!93%3%>&C!"=5EF/!=G@>&<";0G5@@903%5,3@FE:G3"B*8CC*&22*!.@>(-<.:>64$A*D0<)#70G#5;;GF"F!D(644B&1A!@*?7'+?4G8=668/;79%.F(9AF-<B*)-<03"G?4->5)8B4#FD044B?A3=;74@=$,$/7:A@CA<+<C=)?B,"G*,H$E465(CC<A7EC@0'BH8"5!*<,G?:8+(F'4B6,@;H@@$D#@:52!F079'0)A%AB'&/<<D.:4.E9!#5845<E"9<B5&)G9'81)GE,=8--<)3:%8,F$1?6$%$B8#%""H@'%"?+*21.8H*$<!!49!#?H//4-!>2G':@7")?E+(@"0
@r2207
GCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTNTCTGTACAAAACATATAGATGATTAAACNCAATATTACATAACAATCCTCGCACACGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGNAGTGGA
+
/1;CF>:5<E'=B5+4G0)0<*>/,B&5#'9CG1!%4D(;1;=%A.'D#06#>"($A$?94!+%58#%,!$BG=0@.,;C!A0HCFC#>-3B=/''F%;&BBC11DHB<=!:G>-/"'*GD6E?-4HA=0!8(F%:++(5D-"@1(;,:CD&=,*F3##//$F#$D?0-58BA:+1))?B&6.76+&38*E=5802B97(5+8*H!=</050G1;1H9-FD*E;*5:6G*H=E+BD5FE@2!>93H,"C$/*1H'4H@E=;),1C>.$9F2.E>1=;?FA.;@8<'84CH1AFHD.#.G+1$D&@":4(!0"4%;8&1'C5DF*:@(9D4F#+E,11=&-)>2A#G37$E(8-0H1(&9>8'7F*@B,9<>+0?F$?23:-E&;%@'-#/>4DHC%.C&!C90&?FC9:E'/3H$)013+#B)G*'7>>9D(B='-A1+$!'2GE(E'E/8G1/1"8,G9?9H=E9:D/*6$:#@'.3*9>E&B5GDGE$(HF(F"*.42:?7.'3';F6@AD@G.9)>+",)H>'F><'+H14G<"'E&/GBC&(/
@r2208
CAAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCA
+
)%-:<*H/F8@!5:G'1E+=1@GGG23,/1.G-E)29=CG1E"(&%1%8$:/
@r2209
ANNNCTTTGCATTTATCAAGNGTTTCCTTCATTGATATTCCGAGAGCATCTGCANTGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCANGTCTGAGCCAACATGGTGATGATTCTGNTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGG
+
%("&%'*+*("&#%%'#*(+'*&)#+%$$#(#'&"+&!($'('()&$($)'+$$+!#(&()+%+)!*")'!&#!'$"(%((%#*(&&'#"++!")#)%"("+)""*()!*''%%(%%%)#'*%#+!+!("#'**%++)#+#'"#**+)*&)&)'"()#)&**+*!&)#*(&("*##!+!(+)&#('#*"*)()'!*&(!$'+""%%(+*$('***''&'(&$*)$))'+%*!'*"%*)"###!(%!)+(+*(#"(!")+(#%)+%(**$"+("*(*!*)#'+(+&$&#!*)$('!!)#)!)##("&#)+('&(()#!"!'+&'+&(!)#$*!!#)$'$&!#*'+$#!&!))!)%!!!"%($("'*"&*)%+)
@r2210
TTTNCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGNCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTNAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCC
+
'%!#+($$!+%!%!$")&###'*)"!&+%'!!(++#$(&'!($*#++$%+%)(""&)%'%)+#$!)'")!&&+*%'!!!)%')%!$'&("+%)#!%$")*+"*#"*&(!(%)*('$'%)!'!*)"$#&#'&"$&%)##(("("!'()"$()*&!'!&)#+#$+&*%%*(&#+!%**$**%*)%#
@r2211
NCCGGAACTGTGNCTGGAAAAGCCGCGACGAACTGNTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTAGNTCAANGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAANAGACCCGACGATATGATCCTGATGCAGCTNGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTGAAGTTGGNCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGGGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTNCATACATAAAATCCTGCAGGTCCCCTGCGTCGNTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCANGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCANCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAANTGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGNGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCNAAGTGAGCGAANTTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATG
+
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
@r2212
AGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAANTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGC
+
4%G-0E7*>>#A-6<-;:E95,=)<8+H/.FB:B>):;0>=<."+.?>G+1E8.#7'#>14?3/D2BG;:0"+-9*&<F+;(>1F(;65.8"4$6!#,>A':+3)=>='>$#$E/3$>2$>>>0=;8,;*?G*;0D7/-C:8148=G%0%E-1B/B*1#'A<;2A599#;<0C@5>.'!8E"E47"F'4)@-C1;CG7DCD#*(<);E&F)$5",9)5E2)?($:A%
@r2213
GGCCAGATAGTGGTGGTNCCGATGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGG
+
&2=BEG!"C2B4<G6?3:(H'#/$7?#'.;CC9(=,@#';:FBEH755:5BA28.F<<DA8/!=24HC*G8+"A&45B/,H5G+85&806'+/,-A5**H6(13)9AC@)B-('&>+C4D6B/):,?-G;AB$
@r2214
NAANACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTNTTTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACNCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATNGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGG
+
!((!+()"*%")#+"+')'#'##$&")%"))%!(#!*(*#'($"%!$+()*&$*)%%)'%'(!'%(!*"'#"+)($%#$&%!#!(()$$%%&)!"&%#"+)&'$"'"%#'"(%%'%#&&'"(*#'$$%+'#"&#!%"**$"+"&%%!$$!"%*+"$)%&('"%*'""%++)**&'+'$&*#+(!)"')&($%$!*)('+#$&)&"*)+!+#!$"&*&%)%))&')!'!*(()+))#!!&$"+)"'*)%((*%+$$**(')$*"&+%"))(&!!*"!%"'+(*(!"%*'&#*!$*"&)%)()&'+)#&")#%!(+'$$&)#$!*%)$+$"+"'$*&(#*'%+%&$$%$*!$%"*+&"%'*++#)$(%'*(#)"*#&$)%+!!)&!&!$"
@r2215
CCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCNTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGANCTAATCGTTCGNCGATACTATATATNCATTAATAGACTATATCGTTGGTATAAACAGTGCANCATGCAACATGAATAACAGTGG
+
;?4)(0(6)/-E!3/1E,=2>30#@#:5G;AB(1&@(+7D;$/";8BD2#'#=*87?'553'GF"C27@.9!7)@?;;4F"6."B=DG(1=!0%'D)G8D"+49=#HD/=94?'-661,%8,C@9B..DH7";E,*$<)%EAE6#@$&-<B+G22G7:$1>.35C(:G6H;"/91?)0.,/95%4F8(-5AG7B1#:EH,32+@2C4@?EC$A5H
@r2216
CCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCC
+
85:73C>(G2@//=?5H9=''C("H7696C?0+%,*#24F=@,D&-/<1:0)HF6E"
@r2217
CCCGTCNGNGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCGTCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTNNAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGAGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGNGTCTGCCCGTTCCATNNAGGCATACAGCGC
+
')%"(&"+""!&)$('$#!(!%$$'%+%&#+$++"!!'()%!#'$$$**"%!$")'%'$'+)$"*))+!#)(!)&)&$*"!+#)'!)(*)*+#+%#(!+"!$'(&(%%)$!!&'"!$"""+""!!!!*#%'*)&$"""$(*$"%*!''#%%$'#+)$$"+#!+#*(%*$(%++()&*%!'%'(%"!#**''&"&($&&%%&+''#'$(%#*+%&##*!&+!"#*!*!(*$(%+(+%$$**)%#!%$$)&+**(+)$'+**%++!'''+!)*&(+'$!%&#$$"((+(&""#(#+'&(+#$#)#")#+"#&)$$'%&#&"*!&"%'##'')"$*()+**'""(!)!$'#$+)"*'#($#$'")#))&!#"$)"+
@r2218
AGGNNTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTCTNATCTTTCCAATGATTNTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATNTTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGN
+
#$*#+)*)&'((%%+!"""%!$*&$*!)($$(+'$*(+!&'$)%+!*("&+(##)%&#$$!&)+(#!)&(%**(*))$%*+'*#'$(%*')+')+%&&)!")!!'*'*')+$)*(("&'%(&"*("'$"#$(+%*!)(""%)+#$&!#(&)&"&(*&)&')(+$&)!)#'#*&!&($&*!%#""+%*'%#&"$($&)""*!$"$"&%+*!$#$&+*)'(%*"!+")$"&&'($$)%"!!(!%$$!'+!#"(&")(!)&&#"+%&%*!$$'+!+$(*$(*"'+"*((*&)()**+(")&($$!'$
@r2219
GAGAGCACCACCTCTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCNTTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCAT
+
EF3D5#&(26.4)H7"F0+&,%26G;&5G9&/=9.1G3)>3:<3=+8%901!88;?@G>E;?,=*5(=!9<BA*..HCD+"7-B,3B&%0F31+,><"BD*F17-%B
@r2220
CATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGCCGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCNCTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATT
+
H!:=='84=2E&8(4(##7&!"&FA'9*"<5,<E31''@#10-4$=>C((?<?:A6&6FC(2'=3:,B"$:!6!$2+$#HEC*4@4H")GF=H(G5(78%2!F,AC>4=F9)A%!!E,)2*F/F*=;>A3D(#CA":80,>)?/*$3)?-E@*A>/8<@;1*=-(%84>2->0F*A85C)1<<D-*..76B-$"0-<($-,-%=%")4D4!E&+%59DG0'1?$>.)7*5:(2@=A(=:""A?@EA3+?DH)&GD>A$?=<*GA1;!B">4BA4.3*6@!35&?;7F,;!*)>6-!$-7/,8*G+7;2-,(D34;6;"@1"&F4:@*7"<9H;(,%C66@<>)<3=#=9G
@r2221
TTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCC
+
!BH(7,&!3;8&2)?(!(%DGC3&D8C-@%;6A5,+HD3!<G!*=8-%'5&HA5=569;/'-=7.6+12@59D.-6007,'07$21#D2!!38C>
@r2222
NGANNCTTANNTNGNTCTTTCTNTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCCGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGNTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGNAGGGTGAAACCATTCCCGGCATTCATCGTGTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGA
+
"(**#*''*$")!$$+$"#'&)*+(+"**$)#"+*"(()$+)%)+!!)$)*($)!&)++&*+$'$'+(!"+!$**)#%+&#)+!!#$+*!**&$%&!$#%+(%"*+&!))+$)$'")"'()+'!#+"''$%###$'#&(*&#"(!'&$$)$%$&!#!$"#'*%#'!%*&$"'!%!*"!)"')*""'(&""&!&''%**%%"#+#$#($)!$!%+&#&'#)&$)!+!)(!'(&$#$'#'$'+)"!%$!$(*&'+"%+*""(*!##($+&+&"*"&)()$"
@r2223
ATGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAATAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCNGCAGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGNGATTATTATCTTCAGGAGAATAATGGAAGTTCTATAACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTNAGTCTGCTGTTGATATTTCTAAAGTCGGT
+
".D*9+=H.D*E->!>9G&*F.8+2&3CGA;7,@=+81<9$>''C-!*A)+-@,B$@=;&H=D;(1(5$'G?=E:8%9(0C-+H=(?5?>03F0#200=,E/#)>H!3?C:'60/6('>BD>'(D$7A5F73<B*>*;==@8(>/1**FFF80G;C98?2)<""E<1DF'<+)=4D2>&1F@CH;C.##FC?-="8-7/"F>)$$#889;?(!G'5$0B:.+5&E6G22B/@D&3'B7D$F(D,@C(0$B7;,##'.>2186"4E=4-#?4-&3:@2?));::"E51*(<&6G*1."H#A;$#C1C9!;'A:#1+8(,=$-<3,#B7/'8DD6.$)28=H.G+E!+0@;,1>7107/()%9;<%1A348A94=A$;$&@#@#5,C?%4/:F.4@:5*$:4+/'.H<79558@;$F*B<BC>/.%&%9;"D'-4$-/68*.+-B>97E;;C20D>F!A-F7EH9)C;G@;&8$4=D,.+F;@''4;0!!.3B1=)DH/"1H<=B707A#;B2";E/!4-C(@!-"C#$<@0;CC,0C'8+,%($"*E&;8=0H/6!7AF>C!?+61>F/6'><D*@*@1GC;C">.1'29>1H?&+A8!!98F,"9D-<)D2@9=C3"9>@)#A<
@r2224
GTGGGTTGGGTAAGGTTTGGNATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGGCTTAGTATTTCCTTCAAGCTTTGC
+
/.)1/?$,.8(C(ABD3(9/GFE;C%6>9E&)DA<8*D63"6!(A7><7*-4,H(/->,"?F+=@F1;7-=.!B%A1H<'9E(-+)D.'D3>FE::+@!//=:2?1*E4HA2<59</='1=0=@D,6G:1-!/30/F;,$D:>=6+3)4,@?A7F+'"A2,C(-5B*?8%=CC#E!<=.:%F?%)"F@A#';@<H0/;::5)'9,//*F"F=,!7-EC?"G4+/H;*B21H2E&"*E5>'!:9-#!5$2=GH(6',,BH@,:G2,5$4=,BD
@r2225
CCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATNCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCNAGTTACTTCCGGATTTTGTAAAAACAGCCCTCCTCNTATAAAAAGTATTCGTTCACTTCCGATNAGCGTCGTAATTTTCTATCTTTCATCATATTC
+
/(*C;!D4,1/DG3=A)7=;*44F;1*(;+5,?!3FE)!B&(/)E6#1#<<D?33.()146)+/H*=D0C,2#E7)4!8<!-#0;/&!2A:D-H=E:)E'63/8$,)H$(="E2>;H3?#!614,HBEG;$"8-7H#&F$D?F#/G=9,/-@)H3=D11.-F@745"C!6AC>772,B;#$++H#!.'923)'3-/
@r2226
GTGNNNTCCGTCAGGCAATCGACCGTTGCNGCAATATCTGGGCTTCACTGCCGGGCGGTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGT
+
*($"%"+!+"#()%*"+&%($+!#")"!*+#!#"$#&(*!+!**")$$+*+(*$*))*%("%+"'!*%()#(%$+%*#$#")+'!"#()*!&&!&%'*+%$&&$$'&"(')#")$(")*'&#"(*&"(*+!!+!"!$'*%%+$'("*"(&'$"
@r2227
NNGATATTTCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAANATTTAGACTGTGATTTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAANTCTTGCTAAAGCAAGAGTTTTCCGATGGGTTACAAATATNCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTANTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACNCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACANACATTAATAAATATTAACAATATTANATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTNCGAACTTCAACAA
+
#%*%#("#"(*++%$'"$$$&!+&*"($!(!#*$)'&$+((+&+)+*#)#&"$*%'$*%(%#"$'&#*!!&*(%++!'#$)$)(!$"!%(("+'!!$&)$"$'(%*#"+!'*&%'&%'*!#+*!*$$&&)*'&)$!$*$('&%'*(!+)*$("(#"$$(*+&*&""($'+(%$++)"!)#''+%(&+&(++('&%&%'++'$$)''**)"*'!(!+)!'+'"!&####&))!)'!$%#%#"!%)&&%))+$($#%*%$"*'#$"#++)!'&&*+$+$##)%+'&%!%&#"**'')*$+$&$$"*($)#&(!*'$++%'$$+*$!"%(++&"*$!"*+"#%$''%#$)&!!%"!!)$"((%)!*$($"!'%!'((!'&((%+#%"+#$!(&)$($(%**"+()$)%#$&&!&$)&!*)'$&!(+"#(##$'&""+!++)*'')*+***+%"*(!*!&(#'"%%&&'$('+%))(+'+*#*"$&+(#*$*!()%%!%(#$")(!'(!(*#""'#!&!%&+(!+"%#)$#!$""!+#+'($'%"&#*'&+))*$%"&)"(+*(+&)*#!(++$*!))(&#($%*$%$()'+*&!"&)*+)*(*$)%&+#$)($'*+'&*&+)++%*"+*"&!$(&%$"$$!$'"#%''$'$$#*&&"+$*)"$$+%"*!)#!&$!'*$+%)&&+#**$*#((+'"#"&("++*%!%&$""%&"*+'()*&#(("''#%%#"!#$
@r2228
TGCAATGATTCTNATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGANAGTGCGGGTGTTGAATGATTTCCAGTTGCNACCGATTNTACATATTTTTTGCANGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGANTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATACCACTGTTGCCAATGACCTACCTAGGAATTGGTTAGCAA
+
00@A(-?66=2:4F/B7),*27"7CH!B.'+)&5#2+840,=B06F")7),#.4496@.':?,&+=;F;?19>!G<.=BF#;1'CE'G>;!>8!&28'HF74?)9D!8,G-3.>&'5'*;>$$)8)A4>7A"%%(D&GDF>2.!:=F1/GG+9"33.!%3$A(3>B!G9C:/</!)'.@A)6E/64:7GG75(@?8681+5(A:;$9A@-&72C!368$("E,H8.374%48,4FA996F/6<$=,E36(:#2.,C!'3.">*E4C@<'2'*=.4*1C82@D'GG'!#'$;-()9,>.?E=H%%5+B4@6E#/80:'?-&?()$".!4GB*/H?"/5)=.?@4,/6'0=00;+*;?$@/)3+?6.@H$CDECE#?;"@59A?1$>#.?804,2C
@r2229
GCAGATGGCCANAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCNACAGGCGCTGGCTGCACAGAAAGCTGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCC
+
10(-5A:;61!&*7)?0C9)3D+92)&%B.9;/(5F,,&H0).H1C>3.@;"C$=$G?"#9-:1?CHC=/C=+;6350(6:+?&35=;$=C*/<F?<$-8#6A@BBE2D..(4':?B!,D!;>>.$A'?,(*.27;!/;5'A%/:F&C45.&60>144::1,+D+8'H<&9&G:F@<G-@*B<!H9@?&?!*=.&'666G1"G:<!('A<&.##1?18<%2$)E"0#5G8;$:?!183/7F!A"A?964+.+4'2BDEAA,90;H,C,6;"G'<9709C0821.5G1#C?$<.9'>B@/!
@r2230
GGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATNCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATANGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGAGAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTANTGTTACGAAGATGGANGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGNAGACCGTGGATTTCACCGTCGNCGCAGAAGGGCTTCGCCATGTACCGGGCGA
+
70:8=E7.--3)9)-@G>H*8B,/7:9(:>H?&HG4%C**4=,$<>@05E.F"E,(>%=/0F$7"C1:.C'"ECH@"02?A'>A.+*%>C=.)&#?@#>1F45$F0/1#'1$@#0!>->')'"8'D2>)(A#/+)!7G$3&A7@37!8H2?/=A=5??FC=E>#%/HF566&G&C.)6><#/;26A'=FF$H#3*2;3E=/$5C:'D2><"?&>@GH&D/B<-3*&<>$6A#9%&ACC"&;4#F)'0.<+G0BC>0$D3(+D.BD7@/48>+;:C7E01620&'3)4-$@79HGAGH6G?-.+929&!%H*8!$"*<==*:6!*<=A>(81952=;&4<3=*357$CC!A&F8$.6A0:@,>%8!-<D5$9HG.<6#;'GA;,82%=BH!#'HB0%53D>@-#=/H&-%-)2:)-!:7,#C42-GG#"782(!;C)C&77F>-;?-2A4*.H:!"(+!?0,"/=(-7"60BDB1>.:?E.-*
@r2231
AGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGACTGCCTCCANCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGTGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGNCAACGGCGGCAGANAATTCTGCCAGGGCGGCAAAAACGTCCGAGATGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCNGCGGGGAGTGCGTCAACGGCAT
+
H4B956>%("ADGC<((?<82&C>"B82GB?$%?D=BB-4+(.??,7/!F:!6:C('A5B5+3/>+'H.@9AA++0'">B&26$+*&?4<F<#+'3(0/1.$3*#1!%%;(=*'*F7%1'!'9>33.GC;5D7G=/.G)D5<96((?6A"+"?.#>0CBD<A%':GB=G64)?91,?4@"H&A0:'$@+74>9-1@8")/<&+$C.'@.1&.0>-DF@##-0D8)HG1/&>EH##6!(C1.2H,*,/-)42'-H>/5$$$+B&9#7D%G(7(A>3%A.F>G($!(C8$#/GC.54;><."=GC*:G523=!D/7"*3?6/@9.,<;8EG;*
@r2232
TTCGGTCCCTTCNGTAAGAAAGGTGCGCTTTGGTGATGGCTANTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGANGCCACGGTACTGGAGT
+
5<&!@&@2?9:#(>C#),F9H*C$2<8"&87#74*)CGH>?CG<A6?G/AEC"?,54.2)7#8+$:;:<<D+ABD)6+5CE&?:>A"H?87>(1&DEC#,A"$#48.8+".'5/59;96;/+%0.&,!'=&'H1
@r2233
AAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTA
+
D&8?:E=B?"<:.<6$&H15G&5%;H*=H1!55BE'BB1,':8A"&(<),-=33.5D#=0@.E4?"#/3"
@r2234
TTGNGACNTATTGTCTCAGGAACAGGATGGANTTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGANGAAAACCACATCGTCGCTTGATTACGGGACGAAAACAACAGGCAGTTTCGTTTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCNACCATTACAGGAAGTTTATCCACAGTTAAAGGAACAAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCTGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACANCCACGGACCATAAAAATTTATAATCTGCTGGCNGGAACTAATGAATTTA
+
')$$)"#&+&+"(+'!"(%"('+%+"+)$%$)+#$&(*&!(*!$'&*()$+%)%$)'&&"*(("(#*#"#&&&)!%*''"+#%#')+&&%"!&#$"#)"*#"%"'(*&"$"$&&&&*(!')(!'+)#*#)$#'%")*&'$'%%("*+"#%!*%%$!!*%&"&("*%%*!'#$$&!++*$"$""%#!$+*!#))*+""'!$"$$*#%!+!*%'$!$)*!$+)#!''#()$$")!#%'""$*'&$'!%#!!)+!!+%)&""$$'*($'"#()###'&!)%(%+(#+#)#$##&&#&)#%&&%'*(!!*''"+*$'('(+''!'#&#+)*""*#'!(&#$($$%'&"+&$&#++&(%""(!$*"!(%(("*)$#('&#"&+*$')#()()!"*$!&#'+#%"')*##()%'&"))))*%)$*!*#(&(+"")$"#!*!#$&+%+!"**$*$"'&+)**"++*+"&+"$%#(+("(&("*()!&''&'+'%%&*')&'"#$%')!#&#")"#*$!+("%+*(&)#)%*$%&"+$#$)"*+)+")()#&"+#$''+*!+#(!*"))%#"&+#"'$#+&$%'*!(+)%%%((*+"+&&$%!(&!("&)!()'$"!*)"+"+"**#')"#$!%"(&%!")"#'(
@r2235
NAGGATCANTGCCAATTTGGTNNGTCAGGGAAGTTGTGAAGTTC
+
"*"!!%)*#$(#($$#$")(&'!#+!()++'&$"#*#)#%""&'
@r2236
CCCAGGTGNTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCNGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCNATCTGACAGGTGCCTCTCACTTNTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCTAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCANGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCAGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTGTAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTNATGATGGNCCGCTGAAAGGGCAGTGTTTCCCAGCGCCC
+
=909$7)#';C=%DF,"D60?498?;96AC&?)93=&B<,@!0:&4<1738?-4-;<FA;+GH;<1=?/F!1'2'&@1#)<@2:<3@1>31#/G,;#6%;=!:C=0;!>5+>@<=**1+*28;<DH2'5,(F",,F4:A32/H0$-*+%83!41=+0D'1>F+#%7)<E/9#5C+=8<)3469+<4D:'0AA5$9.0#!60G5)?:8E0;60>''FE2,;+17#&DFA5=--2-(G$>$*/F0,7".4"8H!:?;7,88E,<9-<&,0$#'A/<&FG=:(E41/,?51>BDH=6*5A4;0@E"@5+::/&''++0;76HH1*990,-BC5+A>5E;*,6+..<6;$+=.&,H1D1?>+HE9,=2,0FD.!)2<!<&9.BC6+0F.!*BD(726E8?5H>?<%<@%0'2)F/%0C?164D3.5D(>>-G$"F:&3#'##0'4/'#%-:6:;5&'(?C+>==>"'.H;"$+&.D%C5207F'("+B#H1)6)+G>?BB91F,8+'43*%6!=,4/%A&G=+*./F;&5>*;6A'1H087F@(8<D,A'!;211:<0?1C@-"3$F2.!G<)B<4-*95?):?=.;((7$*214:"C8D2@*6<GC,A(>8HF$:1<-:94-%@'9#*)#*BH<C#)0.!AF%);"<!6)+=885<!:&2%HBF/7;GH8"'6!#210-!(B!&?@!'94:45$EA00@;>$*C!D81%D!8A75H&:=15=#)%B,*0'B#1A)!"*007*9.5B0('E<"8+.$*DB%0<;?ABE,'.,?@>**A?6/<A141<"2*-1031!EH/3!(>D%(/'>.1?G/>#G6,>E!:2'B2D21'<A(%#$H=2(H635&=C7=<?5H7F<2%AD,4$;4?:=
@r2237
CCGGCGGCAAATATGAGCCAACGGGGATTGTTCACCGTGGTGAGTTTGTCTTCA
+
06.;"G*2><E0:.23#+@1@+4>C44)83*7.?9"D!-7*9H6)11?G#,H5C
@r2238
CACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAATTGGCAAAGTACCAGGCATTTNTTCGCGTCACCCACATGCTGTNCTGCACCTGGGCCATGTAAGCTGACTNTACGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCGAGGNCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGNCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGCGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCA
+
D4(8!-/H0'AFD%C.9$()C=54.<-H2+>)24/,(=@!5(F7(;D'1!)'9!*!+!-:&D&)+C<)#*H3F#AE"'BDG&"=94D*0(+-#0(7=8,<)+1+-08.G@:*,,>.//$FFG%C+<&.5F2),/0$)4/4D8@G(.:+,,=""0C*9/',!*=8;(H>A-FAD8.("=07F9"!7>/@G!:%C;/$7>:&**E8;#2G6'DB&G#A!;D<G148C<9;$@->C!:#$)=B85$"&(694;A+/D35C;-6E-2*.5DD/!85:76CBD&":<&..?>0HD->C.2#2:+C/4%69(F7F/)2D!%@F?&$!G1BH?"D?#,F9*F)$3-D$=B531<B80?-E=GFA4E&,)+/.+71&B-D'?2H<4(:D=/<8$D6?96/7?@2&$#:09%7/$89(,78.;##DA7DHG#9H>%HB%A$:0-.3>1/2'#!2F?+;'!*071A;$!@!6?;H<9@F#-=D?3593CH'-G.@7:!)5<84%@4*81:-,)-?6:870A*5<-F7$(:,'!G9@5DB:$.&+E?."B(78GD0&+@-1=<#6DG9"+$+=0G4F.7AG$*F?%C$$$,F,5!0G!34!.3B(11E@;.>!/,:'.'.,2=E1@(E583+<=*GE7,@(.*#+&#$;@EDA',@!
@r2239
CGNATGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTCCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACNCCGACTGCGATAT
+
))!""'((&+%+)!**#%!!%)%*"!("%"&(*'"("&!#'(#%&)&&%)*"!+!!**"%&%%*+)*'%&!"%$$($(+$!%"""*((++!+&$'#!&%(!''))!#"&%'*!&+%$+'!(''#$$!%!#!&%)#&#$**'+"%'&%)+$%&')"%
@r2240
TCCACGCCAGCGTGAAGCTGGTATCTCCGGNAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGNTAGCTGTCGTCATAGGACTCAGNGGTCAGTTC
+
+66D5=7E$B5&A8#7+=!'3.@+CB%@#!9*5F)H?A"F/+&1?1"9B).FD'9-,'3..(2/H3EC4!G;&2.&0,.AF70&+:";D")#CBD/"A?F+-=2B0*H@2=B<E.
@r2241
NCGGGGNTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGA
+
()$'*%"+#(*!$!!")#(!&)$**+'"&#'#"**!((#$'!%"+%%(#$(++"%%*)&$("!$!$
@r2242
NGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTNCTGACACGGAAGAAACCGGACGTTATGATTTAGNGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGCNTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATANGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACA
+
#820'5;-4=0>#1#4=D+!>H-004"%H!'%F#6%*;7E!(+<FFG,A*+@@>:>3463G(%=>D$(G/@!"7H8D+,6&,1D05%9!+$)>!AG+6B<C0F7<<BB7<C30?<GC$#!?C,?!$9.6EH222D=!!.=5>E-D,8E4'6569H(85B305,E1A<0-/<6=)!0#;FH/%&3;7)"D?FE+$FH4@=5B</=C3C-88CA+='&G(2$.%%B9.?1/0A;$5%A#C;4*@3:!6+/>(3..67;5!*E6C64;1D*/01?->*2?#*-.-4!6@#2FA@$
@r2243
TCAAGAAACTGATCGGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTNTCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGANTTTTCNCTCCCCTCAGAACATAACATAGTAAATGGATTGAATTANGAAGAATGGTNTTTATGCGACTTANCGCAGGAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTNTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTTCCAAAACAAATGACAAGTGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTNGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCAC
+
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
@r2244
CCNNACGGGNAGCGGNAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTNTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGNAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCNTGAACCACCAGGCTATATCTGCNACTCATTGTTGTGAGTGTGGCGATCCGATNGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGTGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATG
+
&)("+%&%""%#"%$#''#(&(#%*%$''#+#+&%*$*!+)(()(#&$&%'(*'**!&!*')"((#'#)&#$&*!!'!++%$)"*"$%(&!'&%%"++$%#')%"%#($$(+'!+*#!*+%'**"%&!'&*"(')$"(&+(%&!"'+'#')%#!)#!#"$)&&$+(+)&!($%'$++*)+##&*#%(*&!&''+"'"$''**'**+'"&'$%&++!'"%("(($+)!''$!$*!"'%(&##%#&#'%(%##(%!')#&!*"'(++#&*(*$''*##+'!%*$!"#$%&#*%$&+!*'$"***++'$&&&)"'!'&%''')%(*&'(%"*)($(&$+&"*+'!+#+(&*%(%+&#&(**'*#&)*(%*($*#+'$'!"%%&%(%##)%#*((%"+'!)'$
@r2245
AGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTCAAGATCAANCAGATAAATATATGTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTNCATGGAAAATAGTTAGAGANAA
+
2<#058,0;;B/%2$(H?B730EDE83/758=/<.>0D57A(/0528>$9(*0#"E@79D.AE(*4+<65$#;-1<'9!$,C8''.9CE.%?-@?&-::+=&*808*.3E!G<%F09AFE39#E6!5>8/+F")#8(%76?<:1"'H"3!%G66G35-@3?@$"*?7*,7H9?!B/$.>H>@@F/?3@.#A%:9#B<;>%A"0>'93H,4"@D;'71B"G/=A($66-/D,1G8A$C85<D$3F2%)1.-2D?.AD0&!,8*;:+4!E9%)?%G=/%;B/$'11;$44,=@#8C-*$,E")C,E=*H*?((-0
@r2246
TTGNACCGTGTGACAGGTAACTTTGTAATCTCGCTAAGTNGAGAATNGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGANCTGCGNCCGAATAAGCCTCAAGCAGCATATTTTATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAA
+
((%&')%)'*+)#%&$(!'((($#%'')&&'$)+*+&)$$#(#%$$($()#$*(!*)&))'#"+"*!##$(%(*&*(%!%(*''(&'(***(!(&#$'%(*"!("#!**+!(*#)"!((%())#"#$&%"+&(&&&!$*(+)"%(%!+((#*#$#$(*!(!!%((*!*$*!(+#")')*"***+'($(''($!$+$("!'(+$"!#"'+!)'+"*(('&%('&&)'(*"'+$&
@r2247
CNNCTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACACGGAAGTGCATTTATCATCTCCATAAAACGAAACCCGCCGTAGCGAGTTCAGATANAATAAATCTCCGCGAGTGCGAGGATNGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGAT
+
##"!+#(!"+'$*!($(+''!)()%(('')"$%(%%)*&$$+#"!!"+**%$*+*!'!!"!+*"+#)#+#'!*$"%&*#!'()%!)'#$)$**("+)+'%%)!''(%)%"%*!""%$+*"*"&"!%'!&+)"(&$+#))'%#%"*+!!(+&#%*+"&!*))"$''"'!&%&*)'!"&!"*'*$)%"&()$)*)*"%+&(!+"'+*'%%$&+$!*&*+(#*(&)*&%'$$+*)$+'+%"'"($$!()((%$('$)))*'!$()
@r2248
NNATACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTNCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGNCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGNGCTGCCGATACNCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGG
+
*#")$+(*))$)((*"+$&)$("'""&&()!"+%(!)"'+!#"!(#!++($)(%&$#!!&+""#&&+)(&"$#%'&!("$"#)$'+$%*#'#+!#$$%*'%&"&)$#%&*%&$#+$)$((%)(")(&&&!(&#+++'#*&(%%#("!+!+!#!()$#!''"*()'#&($)#%#!*+*!$'($!*'%!(%"'!%!+*'$'++)''$%%'$(&)"
@r2249
CTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGG
+
=6&;=-*+#.4=*<B#(+.$"?FA8E9C>3-648!=--B-.>/DAG:!0>8973'B1>@#@F-C
@r2250
TAGTAACCCTTAATTTTATTAAANTCACCGCAATGTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCTTATTGTAGTTGTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTNGCATGGTGCACTGTTTATACCAAGGATATAGTCTATTAATGCATATATNATATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCNTTTCAAGTACTAATAAGCCGATAGATAG
+
0B!?#5D=#D4-3E#+$04'+5BB.5<0>0A2/(23C)BB$-3<E,?DDB&D<E(2@,2$%.A2;73$%(=;@-A(A8;?"$D38E-,B6-)32FD7#HE>!8*"6E=B5,<1B)5D0!"6$5;F.HE8E;3!D</)#'/7,!-!.E.G-%A+D'>:,6-=#7BA=4/34@4*.%#<;?C*0D-6?C-&E&:.+<+$3EGB=C*7:4+67-8*!>6,*F8H<'0?H1!$E!A+?+5<&3!5=FB7!71F4;:F#(<3DF2D0C%,H!2*E1,<2!A5512:#+9&F0###=>8E8F74')0$,D<81D52!
@r2251
ACCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGNTCTGAGTCATGCGAAATATTTGGAGGGTAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATTGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAATTAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGAAGTTACGAACAAGAAAGCGTCGAGCG
+
"$++"+)+(&*!'"$$!#''&#!(!&*)(%%&&*!#''"#'("&*$&#&(!)&&)($'+*$+#"!+%!"'!+&&!&+!*!(%+*$"(#+$+'$+))%%))'%(&+('!)*++(+++%+"$'$*&%)+&+++%"#"#(+"'*&%*%")&*%"*"+%##&#*%("($&$((%*"+((('))&$!(%('*'#"$')())*'&"%($"#(*#"#$'($*!)"*"!"'%"$&#+!*+#$*$"(*&%*#!*+!%&('$&"#!")(!$'#!(##*"!&&%$%"))#%)&&'*$*'&!"$&!')(**&&*%%$**(!$%)&'&""$)"#%*%#*'!'"+%$$("!()*"++'$$((#)#")%'%)$*)"&*'+&$$'*('%%'*)"%('*+'#)''+!$*)*&+(+)$$*("$*+()!(&%$(&+*"+'$#!%")%+!(%$)'+''&((%%&$)!!%!!&##%%(*&'$#)(+&
@r2252
TTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGNGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTNCAGCCAGCTGGCGTTTGTACTCCAGC
+
C#=44<F&4#7>7B>9H.#,%'F6DA7"A1:>6;+;.>E&,1"/5EH+*8F*1'(($!")$1C#7,"B-#F4-''?@%/@:9@/2=;..<"GC&=A&5B>&DF1<8@H(#)8)H$1>(+%H+1@E($D,B)-
@r2253
TNATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTNTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGNTTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTT
+
F:H>#B=BC43=F/,=.93AFC@!%6*&*(?79$;3@/H=HC;;&"@H$#/2/3C@6/>1E0E!+D6!#B#;%+HF9.@E@=:!.:D0EF;G-G8),';#D=E)C?9H06'H&2594,)C8!)8?22&*G$B73=<:%+0)/>4B%15)<(59%(4;3!D1C5F6A3?7D$4;HF%%#89.3/(E0>68569AF1!G"=/D2+%/?<B+G,8E%=5G)-':7E:C&G+@4<;
@r2254
AAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGANTTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGNGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCA
+
7G8@B.2HDHB"$B#;01E>D39$)1,9#=%D$#5E?4228!;+(1*/*1F@.2*(4'459&;10C<2*E3/';?"#1>$/3*%G-@/7-',1#1='0>'<5G9#C#B-5?$=BHB!0).>9;+GB@%A5<"?7/>5",?8,86/)CE$2:?A:49)(F:EG1?D(:6!728)%"AA.(8
@r2255
CTGAAACAGCAGCGGAACGGAGCGCCTCTNCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACACTTGCTGCAACGCCAAAGGCGGTTANGGTGGTANTGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCNCAGGGGAACAAACAATACCCAGATTGCGAACGCCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGANTACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGANTAACGCG
+
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
@r2256
TCGTGANGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTNAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGGCTACATAATACTGTAAAACAC
+
=>6<98#/A;6*.*'E@77!*3/8ECG&?E@5#-!<F"9G?00@9<$DA9==4,;0>B7+>795/@=AF/@2GD5B4;D(7807=1.!AAG41=H+(B3!#GF+#>A(>*=>;#B(D,#7@<'184D89(>3C%*E%;;A7:"B."F&>D8"9:1H=>H6'(9#BCG'>&30:C<B(/D(A=4'A8563E')H0BG(,09)FF;B(%"+4(06<9
@r2257
GTCTGNGGGCGNNCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTNACGCTTCAGGCAGAACTCCGGNCGCTGGAGAAGCATGCGGGAGCCAATGAGAAAATCAGCCAACAGCGCCGGGATTTGTGGAAGGCGGAGCGTCAGTTCGCGGTACTGGAGGAGGCGG
+
'))*(!#))'')%*)+%#')++++*')"'(*'&'"!("'%!+*(&"$($!))&"$++#%+&&)%&))#$$&'('*!""*)))(&$&"(+#'*)'%#"*)$)(&"%+"#'&*%$(()+"!'("$*"()!'##)#+'"*&)"%"!'+!&"%*$#'#'#*"'()"+)
@r2258
GATCGATACGNAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAANACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAANAAATTGCGGCAATGCTCAATGGATACATANACGAGGGCAAGGCGGCGTCAGCCAAGTNAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAAC
+
DC="?.DF8#7#!H0F3'E55;87%7.-G6&6E9-3=+>'4HAF55B0F0C6@17#-"H:;?B8,D&/.4;--($+;941!5>#)-@D*"+>!G2#4G$+2FCA<H&"!6D6(.#4G5:#A<=;7D5@/-@5%20@819F?*B<6<B(').AHBH**)G%(*7HH$0!2C'%<H,B%+&(H.C1'8;-H>C@/-6)(B"C6HDG3%;080DG(+78+@GG5%881G7@HB3)+76&GC2%#)
@r2259
GTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGGTGATGAACTTGTTAACAGCACCCATGCGATCACCGTCATGCGTGATGCNCTGGATGCACGTAAATCCCGTCTCTC
+
:51B56%H%-&=1<2>,8:#=.%:35*6H35#4<7.B!-H.!&<#47#C(E/%5+D+3%<"A8<C@B%3;3$1)C6/&/02!*63+?G-<;(B5*')C=503G5+44;&)4??-A4-G6#/'$=HA33*!9#7-B'*#-#,?B:11#8(=A<F=:&&)#'FG37'&3
@r2260
NTCACCGGCGCTGAATACACGGGCGAAGAGNTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCG
+
"F0-(3#%'D>>9<A*%,+,B%:"7E@!$*F70AH2A<4EFA.",B4A1745EF/9!29F:(7HD!6(0/DC</32&-EB=E17#?@G35<
@r2261
NCCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTNATGCTTGCCGACATGGGACTTGTTCAATGACACNTCAGCAGGAAAACGCCCTTCGNAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATT
+
!(#&#$+%%%$!"!$+*%$&*&+"*+$(*$**++%%+%&)*'(!&)'*"!(*%#)*!+(&()($+*!*+"$##&'*")(*$"$&"+%'#(*%%$&%*%$)'$*$"")!%'#$%''##))'&+$")!#((*"%'"+($&#"#)&#$!(%&(+*+*!)$&&&)$)$!+'$%+!#!+)*!)"#
@r2262
TCAATTACGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCTTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCA
+
6/!CDC0;)3%FF?A1G*HAD->64CA3G4B.--5H,@.#:280+<'5!$&6;<(12!-.%29>*/A66!6'4GG,E9@5#66(5=;%E8))>.F>7*2G<>2&,2CHB<D#7AA@;9G@*$#BFC+>5@:@B$-D7##G=<7"$B:B;B(1?64B!=21:'F.-#A5BH67$>%!G/(:5H38*;;"2:';>&G'GF<2&9/<H&&0(15.))>!0?98(5*5=8%6#-H4F+7=%745D*E?#8110!?@C*!-&-DG(.(6,".$)H)<,;DF.B(EA-&D11$G3;A5>B?"8&5>(!#',?5&=/1"-EG;@EB0(B!)23?23/5<.'*B.))G%0%'>(&>F6+!6E;15CCH*E)7-13G#<BB(1':).B!C"<6'09FE>2?89620=5B$'20.C)"51F3#9!?,6.4F"H
@r2263
ANTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTNAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCT
+
+%$'!!++*+$***)*&+$##(("$(*&&&!$$+&!&)*)((%+)(#""!'!)#!')!)&(#!&%'(*(*#')(')''&()&'$(**"##')$!##)'*!%)&%%)"!$&%$+*'"+$'#%'#)"$#%!!&*"))++&'("%+$+*($$*'
@r2264
NCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCNGACCGTGGCCTTCCAGCCGGAGGGCGTAACCNACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTCGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGCAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACNGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACACAGATGCCGTCCATGAATGAAGGCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTG
+
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
@r2265
CGCCAGCACACGACCACCGGTACTGATACCGGCATAGTCATCATCGNAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGNGCCGACG
+
@*'F?$B;-4=C<@0BC946;90E7#"CH9(.B72,/?@!E*4194(452#;;!.(!4+?;/"FH=?9?-&A*;/E)-*/,5=:,%-)2/?:(,>'"
@r2266
ATACNNCCAAAGANANAATTGGNNNAGAAACCATAATTGCATCTACTCGNCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGNATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCNTAAAAAACAGACTACATAATACTGTAAAACACAACATAT
+
)&%%"$!$&'#'$!(!$"%(%%"$&+"'*'%&%(#(+)!()**&*$""'*"!#%*'&)*''%'+)&!#'))!$*%%)!')*)$"$&'"+&#'$!%*!)##$##&)(%*#&)"#%!&&$!')#()+'*!%&%$*((#+&*)$*"$)%'%%'*)'!'*%$$**(#+(*+#"*!$%)#&&!+'$!$'+&(!')!*"+$$)$("*'$*#!("!)$$%*)'+&+#!*&#&*))*&&!*$$%&"%%!)!'&+(*)"))++&)#(((&*"()#+)&&*#+"'$")$*)#+$"&%!$#$&'%$"))!($'%*!+#%&%%'(!+)%+%!'$$%"+%%!$"$'+"!"#!+!((&))$$('&)(+()&%&"#")'#!)'($&(!""))$'($('$$*'*!#+)!)('%)%%#&+'#!(#)")%+)#""))&%"(&%$+*!"#'!(%%"*)$)!*&)%++#*%$("+!&)''*$%#
@r2267
TNCGGAAAGAATTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAANAGTACGAGNACGACGCCAGAAGCCTNTTTNAANTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGNAAGTAT
+
%14,2?..7:58?H4H3"=,@$,4A:CEH2DFE9B-EAA*(=F?';BE#)+3,-1)B2()HFB))#E9?2=963#1.6!8BC<8:1AHF?7D(HD.!H1&H>@"2H108B!1A+BG2B5+094,&=#*.56B((331=EH=<3H$(.(&6$+8*?6F38?'C*>(3=)G&DBH@(+'238/B3);D*=DF4B=$#(%.."
@r2268
CAGATTTCAATAACATCGCCCGGTACATGGGGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAACCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTNTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTNATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTNCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGNGCCTGTACACCGAAGGTAAAGCGCAGACGNTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTNATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGNAGGATTCAAATCCCTCCGGCGGAGCCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCNTACTGTTCAGCAGCACGCTTTTTAAGCNATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTNCTCACGCTCCATAAATGACAAAACCGCCC
+
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
@r2269
NNGACGGACGTAACCACCGCNACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACNTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCATGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCNGTCGCCAGTGGGTTCTGGCTTTTCGGGAANACGGGATCACCACCATGGAACAGGTTAACGCANGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGNCATCACCCGGGCAGTTTNTTGCATGGAGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTNCCGGAAGCGAGGCCTGTATCCGGATGCGGNGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACC
+
'%*+*'(+*+#&(($(#)(!)"&$&'("(*!)'*#!+)%$*!$)*"!'"*$&!)!('!*(&%!+*&'(*+*%"&&&'(&')'+##'#$$"&)+*#'$#&'))+)*%)"'++((&")%!++$!#####)($(+%*#+&#%(*%$##*&"$**&#($!))'#'$)#$+"'*&)#(#+'!+*)')&)+)""&*$()+!&#)!*&#+()&()#*""#""'*'("#("+!#%#$%!'$!"%*%%(&&*)$(*()%!!*+$)(($*%)!$*($*#'$*%)%%#"+#&#$$""$++!#*""&')"$&)&)#$&$%*'$+""#)'!&+''#()*+(*"'!"!%)#(%$)*$%&#)'")"'"#'$%")($'%&*!+(%++$"%$'&"$%"%'#&$()+*!+!'"$+""#(&%*&#+)#"$')'&#(("''%'*+*)("%*&&(")"!###"&$"'!*#!*$*!%*($'&%(+%!$%+!(&#+')"("&&)(!!'+#"#%'!"!)!))!$))'!($&%+&!%*%#+'&)*$(%!#&(+!))$)%#"%"&"#%+&)"%!$"%+)$!(")#%#"$+&+%"+(($$%!%)%$&+"!$)#+%!!+%+#)+*#%!*!(#'$##&%"*&)&$#&"&!"$!(&'*(+!$%!!+#*#)#'&"%"'&+))%%"*#!!)+$%%&''#$#$!("*&)#(+(%%!'+#
@r2270
GGGATCANTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTNGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTATCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTNTCAGACCTGCTGTTGGTTGCACTGCTGAGCTGCGCTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGNCAGCTGAAGCTATATCTTCTGCACGTTTTGACGAATTCTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTT
+
!$&%&')"&+&(%(&(%%!"&$"+!)"$'(%!+#(&"%"*%%*!+#*+$")!%"(%+"!*'"")&"&)#(!%&!%!"#*%%'(($*!$'&'")")$)+*#&!))$!+*"+%#''"##"%%&'!*"$&"#($*+$*'$$*"!"!((#%+'*'!%)'+(!()($(+$$)**)&&&$"#*'&$&)&##$!*#'!"%(+&)(*"')$+("&&($%#+*+))"""'+(*++!'&()$*('%*#(&"$$'(&!$'%*+#)$)")"")#&#!#)$#%$'%'%""!$*(%+)+)*%*+%'%**&#*!)$!%+)'$%(+#)%%""!+%"'+&))(%"(*#'*&'$(+%'#%(%$*&#(*'+*&'($(!+$$!("'$!+%'$($%!''(&)!'#"#'+((+!*#%+)+!(&#)''(**++&"&"!&**''!'"$(*+!##'+*'#+(*'#)#!++('!%%&((!%(**!&##)*+!)&!('
@r2271
TACCGCTGATTCCTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTNCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTNCACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAACCTCCGCGAGTGCGAGGATTGTTAAGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGNATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCNCGCACATTGCAGAATGGGGNTTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATTAACACCTTCGTGATGTCTNCATGGAGACAAGANACCGGATCTGCANAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCNAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAAGAGCGATGCGTAATGATGNCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTC
+
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
@r2272
GAAAATATCGCCCGCGAAATGCTGGGCTGATTAGGAAAANAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCAGGATAGCCATNAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATNAGGCGTTTCCATCCGTCACGTAATTTAC
+
/>(H194%EA0(3AF!CF/D&HB0,E!C>.&8077<!$0-H@F-?%A:"2=1F$?&=,:;296-7>:&3D-C:-E;?9(.!H7#H42=5#G,#C)F!?D?C10!14&B)97.@.$6%,<+1221"3&;@>&*04'<&#&+C%/!-G,?6(H>5324")#C99:CE86+@@B97/A'4E@>,#>=)F;@EA(?!!GB!&"D%F(+:9D*%!"G<%D;,7@!,!?8-G2E6067D15-%:6.8!DG/;AB#&D+"79.$.
@r2273
ATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGNGATAGCAATCCCCCACTTTGAGGGATGTTTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGNGATGTTTT
+
2D")&-5#,#8#$.;!#<6.B8'$@C@EE.5DFE87.'-+B6)%74(E*-')B'*$280)8*F"6$7#>($%%E-AC&D6"A#F#$6E6;+4,*:#C:F.A<?H7/,E../(CE86F>:!(('9C<@=/*((?5(C0"/96=:C(<6$='01FC"?633CHE&G:95(/)F=+>96+H+&;9+*#$#48-"*$<A;8($>A=4*=$,D&".$=A*155&'3!2H@<"&BD?>97#8AG-(B5'D!",&D(3>$0G2CHD!%H6*-D?&>;-B?D6<!;;4"%5?F#-G#DD:;3>=*!.6/B1E(,9A>5;><*G5E%AA<#2<6C5;BEA+#->'%7:>*
@r2274
GGAACTGATCACCACTCTTCGCCAGACGGCATTTAGAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCT
+
A6&9;;07H0$(D3G"$,<:2?9"79$>&>--E%B=E-;9D-'(,H;94,5??>B;;!;A1#-,;.</?GE$8?0:88&?3;=3*HF>FFC?9=5G
@r2275
CATTGTNTAAGANANNNATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTNCTATGATAGGTTGAAATCAAGAGAAGTCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTT
+
"*%&&(%*&*"'$*!!"#+$!$)($!)!()"'*'"$%%('($#*(&))+*$$!#($+*%)'""#'&%(!)#%&))")'!""$')!*!#!&&'"#+)&+&()&)##(#"&'%##+&&!"'&%("(&)*&&"$+**(%(*)&"+''&('*)+*+'))&)#$&%++$*'($&')"(**'+'"$$)+$!(!!)$!$$!$&+)+&*(!"!+('&**$#*'&*")*"**#!#"*$'&+'#$
@r2276
ATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAANGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGAT
+
91<6!%B*;D8,7HE<8>?+B4D<:".7*F@.401A7#1:-C':>?;E:.4?9--?H=HC7!A6'/7F!%=>268,HG600$6+B--&5*;>G"3178'.H6="A9F!'*'<CH8HG0@5H!5B**0H6!!<,!'-F=B*0+;F1%,G=0(!(,=*5:"A'<G26E::,$F;/6394>G;475E:18/#2(08=C!!>;D15787A8674!:%85C1%$A+"BD/:&BE-@>C';33+-92A9277
@r2277
AGCCNCGAGACGCANNNNCGNNCCGCGTTTGCCGGAACGGCAATNAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTNTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGNAAGTCTATCTCTCACAAGTTCCGGGACTGGTAA
+
('#'$$*$$*)$!%&%&##'!"%$+"!$($&%&*'$+###&%%&#$!%+&!"($*(&!*&%+!*'(%&+%(""&(&)%!)(!!%**$%&(##!%+!+&!*#+$)+$$&+#*)$#%!%*+!#$*(#*(++)!&)"$$""'*&'%"%&!(&&')'$%*%)('*%+&%!'###&*$'%!$**'+&#*%+'!"#$%$#**#!('%"%*%))'%&#!'("+*%!&'"*%!%&%*(*!'+%*%%'))%"*(*%$%*&)&($'!
@r2278
ACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTNATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCANTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACNTTGATTATTGATTTCTACCATNTTCTACTCCGGCTTTTTTAGC
+
<2,8'66+G1#?1;@$+0/()@D,6@.(@*:1$*$1H/@$*>1*F@F,?:0.=$-H-)>7")'@#@;.(G#4'/<9HGB$*7<8(%;/-9H.D76),73HB',<:7A&/.B><3&.<1B)3>GE?/+#4A$7+F<'1:DHC7,,B,/>;"+74#>5!@9)%"/G!&>3+A015;0@;6-FB45B#G':3."6(0G8&EBE"/>&B<?C'668*<@)-F>(5&*.?HF.B./=F5-EDA<8+69>"6F::12;HC1@=%=>!E/H:;4%!(A-C3,F<):D>/C15<!4F*G$5";$@05BB(B'&,DA7)D1#B"74!AC")'6$35E
@r2279
GGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACNTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCANGACACAGACAGAATCAGCGATTCTGGCGCACGNCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCTGTGAGGCGGAGGCTATTTCCGTANGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGCGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACNGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGANGACTGGTGGCGTAACGGCCAGAATCNCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTCTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCNATT
+
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
@r2280
TGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGNCCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATNCCCAANAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAG
+
B30(H-,&3+F17C(>B@7H&81E#%G5??"!79+!=379H1)!4!927GE,'*F,@39-<2'4H7.36D'FC)-/:?/4E4=(<6-8#H$3-3,=;C<<:5'FAH<1&$*#6A#%($@<A%$<C(5<G'<66:3BH/,F$<1>23G2135BCC,2,%F16GD&1?'!E")-B-9;5#7;#/&>,A6E+/H8@07>G(H1G='71@7!0(8$2><$4)<2?1H#-@/,8A#2:@(1>0C586B4<2C*8.,$<-82:*:+G9=58,%5,&(-!#E'>4G10&HEHF;2G9B.("=$251A.$;BE*$)@"%#CGA.C>90$";&*26,&E4(B:D'"2)&:%G9$="&77;007-EB2D)08B
@r2281
ATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCNCGGTACTGGAGG
+
38)8:5".?6!-/-6G08,?($5$2911<H"3=C+!=;;<4$27+5"<%!7,=:CG8:);6,6C#5746<#=.'69,)G;@6+F+<,/,&=7?7(B*E8?$27':6(-0>$3E!B13=9>,3;&)%>G'/D9.>0!(E4-D>"%!8-
@r2282
TGCTGCTGGTCTGGTCAGCAGCAACCGCAANAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCANCATCAGCGGGGTCNTTGCAGGNGCTTTNGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACNGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCACTAACACTGGNGTGTTCAGCAAATCGTTNANGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCG
+
*'**(+'&%&()&!#$*)*$!'&"(%#&')#!)%)"+'#+'*($&$%!()(%#!%*#$+)&*!+"$%#$&!##%!$%+!!&#+(+$(!%#%$&&'*)+(+$#"*'$&%*+%$%+%(()!#!)+$$+'&*(%"*#)'*))&$(!*"''+!)!&'#&!'$%)&$'#$&(%+'#("((#*#$*'%#)(")'%%&"*$"(&((%#&"&!#*'&+&&'"+!!&$'+'"%$&!+(()#$#)*!+"$"*#*&%*"+)(%"#&('"'$'*#!*++&(%"&*#)**)+$'($%)%"$))$()'#+'(*!')+!*$*%*"#*'!%&"'!()"**$+"(*&%)"
@r2283
ACTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGANTGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCNGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTAC
+
*"A%7232%60EH<BG$@"9"48?2.(F6:6GF*0<F.#=2F%?@0E5*(-;1A0<)A4"'"%##!:$GC"&4!'4=!?A,CE2?*4C=!)G=+=C?4#+$>9%37#*#GEH#./4./%7*4A+3#<#(B,0<E2*<E06#=37-7+%$"H/(A,4-E<B'(G,98&&0!B@B06DE=15%D#-'-#,A2<D30G.4-$'3@=-H(BC;&E80&A6%&*7;02CA47+%=<DA#35AB.%-.H<<+9+0+5:2+-55"&'<&.)=:@.FAG2%@H14E04%::1=<++9F4@)#<&=FAH?=;67G&$5@0F"918299>B.!E32/50F;%*4),F*+0"928$,&E@A=/)!3@092)C54"567':A2?='*>0&B7$8+&$?*F&/"))$02BBA%7=8:01F+7@?-3?E4#*?F%2@//C((.!B@0:"A1:G?G>>$/5*'4EE4#,0B##F=&-5H3"@6==&@!2<(BE"+5.A5%%#+0!'),41<#G%;60CC3*)DA*%1A==88-$B*(*;$@4($%94%=E;@A%=F:'!&:H.$()>.DH>#8C?!;8=9-DH..&(9!10)%4(*H*<+,=)9.<502#+.%4FH&7$3!)55D?#6),B#955!"+?9;F!"><?*%H-F--*8ED5).3@?$@;+%%9*%E+5+*H@:)*:H*$#(!;C>#H5F(30A,F5H320@.,E/D73%0D(>2<'!'#;B?!&A<=3G62&/>3E*:A7;G;($:%::G=3H50@87<&$7H);C,47B+*-E2(6;8%B'49%#@EG$3=EDE3!+3.2>35B70=*250B.'8.B=%,'?.-7-A..07D2'=.)?F#8$=2/G=!3?+B#(!<@7G%,!-9!&>E:-6H$,-H>-C(/1.!700=44
@r2284
ATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATANTTAACTNAATCANCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATTCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCATGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGACGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACCTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCC
+
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
@r2285
CTGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGNTAACTTTCCNCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGANCAGTTTCTTGAAGGTAAACTCATCACCCCNAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTNAACGAGAATNAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTNGGTAAAGNTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAA
+
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
@r2286
GCGGTGATAAATTATCTATAGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCAT
+
5G>=@#+&:0;9?:,!H(/<8>2B3EF*A/5)1/E<@=)':%@3CF%37G+C>(<C.(F=85$F"B/D-E$19(<),:%03(&?-6%<;BD0+08<3:='0A=/:C7:8&F#/?7&'(@(AD3/C."8'F9D4$#<CH",(+"+>;?./.)H0+*8<1FF4*61@+(&=6),1
@r2287
TTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGNTTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACATGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGACGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTNGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCATATAAGAAAGCAGNCGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGTGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAANAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGNTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCTGGCGATCGTCAGGAAGACNGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCACGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGATGGCGCATAAAGATGAGACGCTGGAGNACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCTGGAGCGCCTGAACGCGCTGGCGCAGCAGGCTGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGANCTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTG
+
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
@r2288
GGGAAATATCTTTCCCCCTCCGGCGNGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACCTCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACANAGGAGGCACTCACCGCGCTCAGTTCGCTGNACTGCTCAATGCGCCAGCGNCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGNTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGANAT
+
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
@r2289
TTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCCCTACAGTTATCGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGANGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTAACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTTCGACAGGTTTGATNACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGACACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCANAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTNCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTNATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGNCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATATATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGTAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTNAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGNTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTNGCTGACGCCGCCTTGCCGTCGTCTATGTATCCATTGAGCATTGGCGCAATTTCTTTTGTNGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGC
+
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
@r2290
TTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCNGGCGTGCGCCAGAATCGNTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAANGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACC
+
*A3(,3H#@(*<%)&8/")8,#:17/1@0>0!BH,%9H-'*G."*+-$$=!<>1=F.=0BA2:<2/6>8;G($/:<0)E.F3(4A36.<D0)-B+-$-%,8'<*%3A4*2*7,0/:C)(;1+,)/8+<D3C:!C2;5!F4GH">+CG8*HD1C6&4A&H50",#'.7@@FACB3>C4./)?2%0$//
@r2291
GATTTNGCTGCCTCTTTTGAGGNCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCGGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGNGGACGTGCTGGCGGCGCGTGCNGAGTCAGTTGCATCAGTCACAAGGGNCGCGACCTGAGCAGCTGATGCACTGNCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGNTCAAGACGACGCAGCACCTCCGGCCGGGCATAATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTNCTGACCGTNCTCCAGATCCATGCTGTAACGCCCGGCTTCATCCGGATTCNCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTC
+
&**+'))'+'"!%)#&('"&(&)'+*$**)"#!('*!++"!'$##%$!&"*)(((("+'+&)*(&"'(')#$)+#+'+'#")*'(&#!)(&*#*%!+($))(*)""+)$+'$#+%'))+**)'))+$%'#(&#+!%%!**"+&+*'#%*)$'!$&)!&(#(!(&"(&%"$%!"%%#()!%+&'%*%#"+)(**$'&+'#!!')(+%("("'##*"!#'$*%+"($+&%'!&++!$(($)($""*+&&#+(!$"#"$))"*"%&)*&!%%+)*)$'+'!#+**'"*&%!#%"+%)%"++$'"!&#(!#&)%"!+%$#&'%'()(''##(#$+%'%%"+"('%""#!'')"+#)%%#+&#""##""%&#)!*#&(!!'$*&))%)(*%"%%+)&*$(!(&)"!)%"%)'*))+*#)(*$%")"++&*++%'!#)($&*#)!*#')("(()()+*)&$'#'($'#"+&')!)##'""*(+(!'"!#&'$!'")+!$"+$*&&&!+('&"!!)"(++#"+*#"#)"($&$(*+*##)!++(+)%"$&#$()%(&$'$%+!#$"#*&%$*(*!&)&%#!&%*$!+("*#'#('%&'"&%)")+*"%%&"'$($%)%")%")$*!*(#!$('$$!'#!'&'"$!!%$(+(&%(('"%!!***!"*%*%("
@r2292
TAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATNGCTTCAGTGA
+
G:?5:&*.510GEF*G;?"4@#(=F#D8@)<8%!#BH'7-11!92?,B0'(E<046<*&8H!-CH8;B3&56=5B2@*;B+%1/<8#8;
@r2293
TAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGNAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAANGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCGGGTTCATTAGTGACCTTCTCGACTNCGCCGGACTAAGTAGCAATCTCGC
+
/CD=$+CA:.%&3,*D6DEA7F&:62&2?8-:C"&F&&"76>:/#&<B!%H:.3?./A@H/E?"32/#+;,"?';H(./25F"-@A*3@A"?!(+-&BH=-#(=(F8<A!#.3-?F.3&6)?A:+6C>.#,#48"/0%"EH!,0B65H2;"+C1)$EC*$*4B0G0?F9A+27=A*@+H@G?>G(!/D8;(/?2&C%@9-3:2@2=,5"%7,F,3/E41E525%9),GF@%;>$3'.&*'<E5@+&?%BF#48:-/F5-%#?C='D4<"$#1A4BG=8044,/?B#:,"'$E$)<:%:H60<1@40G#!1?E+2!9#%D(<,7;.E7>+"224$5C8A%,+@7964C9B1&49B<3#*C?-6?7?&HFG<2-%/:%+.#<:"6H7:@6F71&8B-1,(863C!G:!3F40)4535
@r2294
CACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACANTCCGTCACACCGTGCTCAAAGNGCC
+
#G-7>"D>048$#3#=HG$"7-8*GE%;'B,#;F:'85G3((:"B(G+=(A4#E!G*A5"*199*0*,B6D'$(@1A)7DE3/8?7')9>"34F7DEE?6&:&
@r2295
ATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGTCCTTACATACATCTGTCGGTTGTAT
+
:D'*49E<"6&HFF!(H!9?5?&F!(3,F'2A4(<62,'7%4>*E!9A7,6D+2E)>HC$2D"-)D%/<*!?*<;""7(C/7
@r2296
GCNGNGCNNNTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGNGGCAANCCGGAACGATACCGACGCCGGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTNTGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCTCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCG
+
$("$&"("(+''!!%"(#)$)%$%"!!***#+**!"&$&%*)&$!&%#!(&*+"%"&+*+&"'')+'%$#+%&$'*)(++#*'"+**#+&)(%%&"$&%"(&'"*##'!*!!'!%#!*$+)%+&%#'*)"&%'!&*'+($"&+(#*#$('#(+#&##!"*#+'"(!(*$&!!&&&&#&)(**$"'++("')++!%+"'!+%""")%##$+&$%$)"*!$#$%$*)'''$'""+"&&(#*$(*++*!(%*!+#'(!%"&'*$#'%(&$""(%&(&!!#'"++)*'+(+)&*"'(
@r2297
TNNNAAGCNANTNTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCANCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGCGTTCGNGCTTNCCGCAGAATGCAGCCATA
+
%"!$')$&#'"*#+$!'&%'&'!'+)"#&*"&'!()'!!&$())&(%%*+)!'")**$)"++"#)''##*#'&$#*)')*($+)%&'#$"$&#)+)'+(!)!$+$#*%%('")!$%"#+&!!$'!+"&&!#"*+&(*(&!("#$)*)$##&"+"&%#)&&(!"'$!#+"))
@r2298
TCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGNAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCNCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGCGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTAT
+
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
@r2299
TNTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCT
+
*"86:*16-A';8HA??=+.1=6-$22!3/=,H2,HE&+7)>,$*@)";22*/</2
@r2300
AGCCTCACAATATAGTTAAATGCAANGTTTNTGACGGTGTTTTCCGNGTTACCCGCAGCGTTAACGGTGATGNTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCANGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCANTTGTGTGG
+
;</*B2";=9B!<*B,G/<D854+>GH(F7GD8G@<*HB.E9D&#5>)G'1F#7=(2.,66CF0<.G-@=)@&:GB(#4*<5#G.--7H<!="5/E6&+-)1#)920A933&;DC.@"42;$<B-23AG8BD*G1#=/:7@C=$'0!$937'&5$0;=?>#37,592@(?$(;/4%GE7C8DF@?@>@<9((2D0E%A?>(5?53#:%*;E3#$%>;!A*?BGH4;G))-#E&6%(06:A'1(,!5:;$H$'2)DEA@EF4?<$%(@*1H8%6.!,+;D!5F2C35-B;1&!;<8>)82'*>"0#1H$%6H0B624GA;0<%H>?D3)2)9C%38+;1"/@,8;7
@r2301
CCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAAATGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTT
+
GEGH9D00:$E/9E#<;FCB*E3-@C30%44'3:4*G0&A)!"!+<E98'&*@&;3/0;(/&@FE,-A$/#"%?!>,F:")/8C-;CF&92E39,G1H-G,D464B&CB&2#F42354457C!#B:AE<#&H-C<%0+C.BB?%4@;#=%>,6D1#;'$-=+H=C$!+7;1=(+@!@=?-=09//#/H
@r2302
CCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCNCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGNAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGANGAAATGTTTCCTGTANTGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAANAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGNTTATTGGAA
+
9"C>0*);2"F6<8)'?A&03(F;<=E""DA>*B.5=A3+(0GC"8H"1'6*,+5'@?,987(;DG.=#GC6C%.5B4C-F4&"/0?1#@4);@D:/@C#;H'<?4,1'#67*G?A1@*5G/2:16D4.<"3+)6=BEBF7781G7<)>7-$:&:%%.*.4(+4>HH:>+G!#$GCB1"+(@?H7298(.=-BH&-=9G2(=/-38=@%.(EC?6F:+'4>B?6=;.,!99H!$6#&G1*%(07,H35.-)G).2.A/$'+EF>2</794>$!6#'6&*%.+045)CBD#6=(-?5&*D-:-A/6&44E:,+$)(&-99>:AC&"><E8;B"80C@&=-D'1!>")AFFH7.$<*G?&;"%F()E23,@2*)E+A,;&<(')CE*8033H93*=34;5"64F8)!*5G*9=;:G%
@r2303
NTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACATGAGAATCCAGATGGATGCACAAATACGCCGCCGCGAACGTCNCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCNGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACTAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAANCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATAATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTNTTAAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTNGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATNATAGCTAAGACATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTANTAATAGATGATTCAGTTAAATATGAAG
+
)(+&"%!%""+#*!'%+#))$&'#&+%%($*&##**&()#($'*(#"%)'%&)"'#')$"**)#$"(&+*&%**"*!!"'!%$'%'#'*&)'*#+$$$)!*%#'#&&*!)'##!&("(')&*+&*$#&!*(!"#$#"#!%$&#)$)''#("'+$+*%)*"*%&*!*!$)$+#+*$#!##&$)(%*+%%%)!""&!#%#!"&)!&)((+#+'+*&")$+&$$%"#)$%+)$)()!!+%"))"+&!$(%(!""$"$!!+"*'!&##(%"($)&%#&!"%'*&+!#)*(!!)"%""$!%'%!)$*'*%#(+)#+!)!*++!*"&"*!")+%))!$"+#*"!)()%$'%*!"$'#')*%+%#&()+"!$)&*'!+#+(##$'$%+*')##)$*$+!!'(%#**'%$$$%+)%()"&*$'#"$&+##+"$*+*+"&'*$('&+"!$)!(+*#('('$&#)+*+"#"'&("#%)'&'#!')&&*!)!$$)"&##$'###'+**%"'!"'$#+(!(%!%!)!+')&&&!)"%!$#'"#'#'')$'(#!%&#&'*$!++#!*'*$&&$()$"((!!**##((+++)(&*"&"%'#(&%&!)''''"&*)+'')!#***%($)%"'"&*$$("&*(&&+))'))$&%!"!+*$"!$&&+%'#!'(*+%+%%+))*")($%'!$+)*%"&*+*)'#$!&")#")"%++&"&#$'%)!)++!+"++($$+%&*$##%+#($%&)!*+)!"!%+$#"#%!%&(($'&$)"'!&!)#+$+)*%&"%&"!(!"&("#)'"!++'+#%"*$*#"$!()"'$(($((&+#+!*&%#''!#!"$#!)'&&("$!#&*!"*"!!+"&*#%#+''%*'!
@r2304
NGCATAACCATCCGCAGAAGACGCAGATNCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATNCTGAAAACGTGGTGTACCGGCTNTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCGGTTTCTGCGGGAAAGTGTTCGACGGNGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACNCGACNGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTANAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACCCCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGNACCGGCGCGAGGAGCCTGAAGATGA
+
#+(A58%FC";1H.>=;1>H&./=0(*93$!7A8#B(F90+@@-"<10@H5&&07,-B2>@5%6/%0#)F;$6-E/;92E*<1/)<-+661/5,H&3$+60'9@#7%"%B!%DA@'5.%<8?>7'-G4=5:&B@EB%!!E67&,:E!66.C@;F11.A-,=78A2C('%3E=.=,5+$3%3H1H,(0D%5'4/8*C156#>4AGB;9,F+)0&3E$#:E$/1+;%,1E@3#23$*&+?0.9BGB)%7-&7+<%!$@,0D!+9?&&FA+@>!C(#9=A=B+AH$6@'F@404-B@3.='AFDA&G0B&'05)?B1/:6,(*DG<?D9-.)0+#F436:)F-E25BA?B*2->(@0%:!8'.>0)?H,:*-3;<:>7*-3#)>E8CH55!*)82>%3$?'@"-:2-F&:,&E%=E3-;+H9A'/BF2,1EC<'=FB5;:(F0)D8!#-$E!B6**<)6/+3:-C2!AH3?<)*9:3
@r2305
NCCNCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGA
+
#3GF<#-@?50,6*8&?($.5:;A8#>+?57C;(F-=>7505B9C+)=>5(D"05:7<H$!;;/?,%4(?+9@*C2B!!2++F-(G9(?'924<ED1#2,'70:795<15."9-C
@r2306
CNCTTCTGCGCNNGAGGACGCTTCCTGAGCTGANGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAG
+
("'&+)+&"#&%#'*(""##"$"&")!")$)%)**+'')##(##%"*$%*'!(!"+%('$#)((!'&%)*+#+#%')'&+
@r2307
TATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGC
+
F)9->6/)<(A51&@!8.9."@'!D*7&?0C':</#%43F5%&0$+,6A,F+*'1@B%/C'B9.B
@r2308
CAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGANGGAAGGATGGCCTCCAATGGATGGTAGNGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTNTACCGCATACCAATAACGCTCCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGNCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCNACATACTTAATCAGCCACGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGATGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCNATATTTTCNCAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGNAGAGAAAGAGGCA
+
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
@r2309
TCAGGCGGCCTTGATAGTCATATCATCNGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATNCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCAAGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAGATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAACGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAGGATTTCCAATAATNAGAACAAGTNGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCNTTGGAATGAACACAGTGCAGNGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTNGTAGTCATACGGATAGTCCTGGTAT
+
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
@r2310
GCAATATCAACAACGACGGACGCTGCCTGATTAATCTGTATACCTGCACTCCACGCCACTGAGATATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACNGACCTGCNTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGNTGCTCTTTTTC
+
2H6?#=9.@3$/B4B-+?="./:"61@,"><1EF&9CD='D!6(=-6!G6981F;D5H9D/B%#A?0&G&A!%GF3A0.(H'C:/1E<D'FHH.(E)*%;&0H9?)0AH5)'!9:HG42H?D>"0E<$C%-.87@#5:ECE26C1(#9;G'*/(%C5.#89+;)=;DA',73F%87$/%'';H$21.)F;5A9"(9+??*23(7"$&,3%$7G;302$3)-!)):F/!;:74!<-0742=C96!G45!;(@.G#+1)4.(A2BG56@-"/,A#<A=#+E)$26/7!<4F(3>F=;&<)-$;3*="1C"!
@r2311
AGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGNTTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTAGAGCCATCTTCCGGATGACGTCCGGGAGANACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCNCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCNATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGNCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAATACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGGACGCGTGCTGGCAGAAACCCCCGGTAT
+
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
@r2312
GGAAAACGCACGTTTACCATGATGATTCGGGAAGGNGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGATTTTCCAGACACAGTTCCGGATGGTCAGCCCGA
+
(/-)2?A903A76)!A"F1:)72=$+A=-!#0&B(>1$1?"8:!F64D#)#-EFGG#",D)#>H1'2%B?/1=-6;-+0=HF?:)6#E*!:1%6(D.0-"+9(.A"2;#""A%!<'@D%1G:8:-*,?,71:F2:?
@r2313
CGGNTGACGTCCGGGAGACACTGCNGTCCCGGATGGACGCAACCCGCCAGATTTTTGCGCAGAAGGCGTCGGCATATACCGGCCTGTCCGNGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGNTGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGANTCAATCAACAACTGNTTCAGCCACTGNTTCGCAGGCTGACGTTANTGACGTGGTGCCAGCGACGGAGGGCN
+
D-/+-1@@*8C?F!4$G@<3GA%3+0F*FA'D&1*3-&.B'8,12C@&??*4"!'E*01%A.81"(B$4G4##=5!!4(5$:'92B-2.F&AD&)8''0!E0/5E*>!@B8CH2+G&!D5!B!#67)4#=A=C?76;B2:**:@:C?.H3A:*+'3!.ED.11'"HG&%0<&"#%<GD0/'F<E,G-1"/+5%CD-)(G:%/62D5%CG)8%9%7HD&*5=F1+!D7'A/0-63E9'9BD5$9F4==/=$.1*+!=5,9+!$=*7,7G/(G,)'7=6"F(%<&&".=)<>AHHHF+@GA!6H;+3:-+93?&&;'==(%/1/'&+4"
@r2314
CCTTATTCGGAGAGGATGAATGACGCGACAGGAAGANCTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGNCAACAGTACAGAAATACGGACGAAGGGTGAAGTTTACGGCCACTNCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACANCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCAT
+
0&6!$E4?(4:!?%3"GF1$F:97A<F683$;%H;);07D#;#D71/=847*>+'G#8/<0D58*/B5"D$CAEB5::.5"8D?81:2C63H0)3EB?$6C-B%(00@0:'#<;'#88".70)-08?9.:BF*58B/D+A4!9"%?;2"1,'!/&=D6$4%5&7/?5?1,+:1(-.;8>6,6=='2"24$)79.!=%"!+..B"@,477;D3H':,E:''.C0+#20:BE"%9%-F(!'
@r2315
TACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCNATTGTTCATTCCACGGACAAAAACAGAGAAAGGNAACGACAGAGGCCAAAAAGCCTCGCTTTCAG
+
.)>3"3.>.&H(44D?239G24>5<8;!C#>;,(?::0@&%.=$G'1#-HAA+!FD:%,G-D9)0#@:78,=@>B$+>5F%;5CF6!5.F0<%H.77<E'E*"0A<,6D/H88(('2H(<HF6+0((@3*;!?;/=:)@8'CDD8/F>)"<!@:-<+2>!,<#
@r2316
ACAAAATCCGGTAGTAACTTGCTAACCAATTCCTACGCAGGTCATTGGCAACAGTGGAATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACATTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTANAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATAGGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACC
+
5E&:A9.6)F5D!$#0>2E:E/!1G/C")@$-/0:79.2H/=*$H40D93%:>AG09<H88=C#=)A<GF'&EH!E0!CF:2,-F%#0&*/G61<H.F!;;+H#">:20+DE'E-G968FD.$+"D!()95.2,C5%5=).D:EG=/-D,(4#.(>#'H4+5&?$)?=-$BDH&14*92:'"5>=2"1E8+<1:)/@)G25>%02#0C7>;!:%/!H:35'"!!@2F6.8F;7G"0BG</F9H6/3'B-&.6FD>?/"E540</"?B(<>/=:<4;*-A2GA#A<C'(<6G270G>)-0&G:H61=(2A0=89(;H-8$="(7<A:@@<,.*A;)//89F$%8-$*.C&()'?1!?+,F*(9@3&/@'#D39?!'@)H'+</!1D74")";@A<+':3709H1?=18.GEF)999#"!G**A.;B&2$D>!/DEHF&-H<5A%G6$0991=<A*8=6)>B>D>+
@r2317
GAACACCTGTACCNCCTCGTTCGGCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGNTTTCACGCTGGCGCGCAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCNTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAANAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCT
+
6!*%9)?D&&D,!.)-@;5'%$'=.<)D1GB;<;!13(0$C)!A",0/3<E=HB*CC"6+9@#FCGCG)G9&6"-9E/CAHD*+EC+",-)?H2G<%,4E=:C:8%):-?B72$C6B.*#G>E&;BC*3.7;%$CA,C;E:AA950&23,,#?20?6(D<05F(0+:)$2BE"*8<.@68H(F$9DAD0,9>E;D=$D%>;E.(@6D'"*-EF(G+(=##8+9"C#41@@/82B.281A&@,1*.42F+/@9E@)AD-E@A>4.9&"=F6C:@$?;&C+3@H1+"6D#3GG=7A&C?)*->)&%9C<,:>"GA4/A!'%&<>:*)#8;H:)<G/>D4C"40(.8+,C"/6>;(48,H(8B5A:$+=2%H@":(4.%0:E5-8A#?!E>?%:6H.F)F@:5:7%20BC:H:&C<,%,!+A;2<&H$306=67:CB44*,<?7:8=<,B'B<2G./E#EFH=G;;%H339;!2H%2/'7:$"D?9#
@r2318
NTATCCNTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCNGAAACCACCTGGCTCAACAGNCCGCTCAGGGTCAANGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCACAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGTTTACCCATCTCTCCGCATCACCTTTGCTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAAAATGNGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTNGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCC
+
!+*$"+(#(($!'*&"*$&+#'"'+#!(#&)++"+)+*"$%!$$'#""*$%+$#"$*&))(++"+'%+!+$"+%'$++')*%!'()##!%'&&+!"!*&(!*%+*+%%%)&"$!!*#'&'"%%#%'!))(&(#*(")"&)+""*%!#%&($&%)*)+(!+%&#%*&#&'*!'(''#"!#'+)%)!(%+)$$*%)&*$%(**&#!%#'(!+!("'&(&!!')("++!%#()*"#*&#+*"&*+()!$!%!'##'!*!#*$+*#%$&((&"+)$%'"+!!%&"'#(*&"$#+%&!#!)+(*'+)&'"'&%&*&*+!"&"&"&$+%('$$&&!#)%(&##!#""+$!)*$(*+$)!())+"&%+$$$+"'##$%+#%$+*!"!*)%'&''**&"+$#"))#%")*!'!$*!&#(*"+)+"&+(!'*+*&#*+!*
@r2319
NCGATTTAAGCTAAGAANATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTNAACGGCAGGCGTTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCG
+
-G&E.''>.-C8AE4,;$02-7,6C%)G@'@DB'G4H5>05D0<A>?,D+A,*9&%EFAF9830(,'2C'>/A>'?"3>6A@8@9=?>D>7G#D>(2'5?;A<%4GF+0C$->DC.8AA-6>9)HG20@"EA**9*($%'$6=9@03<"73BD752/(/72>(>$H3A<3/43E970;.+8*:H-D1.%)'3C%1.4/,>'DB#'/HA.27$<2*1);"HC=2"A=:;(*<44BA5602@">*43:D,AE8&H!4-?>%<<$F2><#%+&*'$=C=+0AFA$0/(>'#"'F#1F8#E=D$*E"@)3?'79$6$*:H5*.G-&+C%6<EH$9CA"/+4B@0&*!B'55.%%B=H:G+(12<=5>;$@;@?-.#>(#
@r2320
TACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTNCGTNGAGGCCN
+
7G/*59"G-'#GF5-4*4&7.1;8@"=%6#0@%"D'&72*!-#?@1$7F(6BD@C&F'2,G'C%.GE):/;D;73*6?D5GFE*@?69#.925+$"6069"'1;C>.$0H&0$H2<C=CEH=C%1,:,4*0A)
@r2321
GAGATCGGTTTAGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTC
+
.G3)3/&!7=/,)D=(%&)74GG>1*F7EF-/A;@)B91#";=E@G03')HEH;0(*
@r2322
TAAAGANGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCA
+
*+$**"))(($$%&')!%!(!'(%#)&)"&$!"%)))&'$#%%$$(
@r2323
GGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCNCCGCAACGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCG
+
+*%*&%(*"(&)#*+$!####%#%+*'!+!(#*!%#%!'(#+"++%#*")**#$!#)*%#$($&**&*#("$#%+')&!"+)%&'"!&"(""(('*($&#+(*%&)*"!#&&*#'#)&$"&+%++)++*%!'))$!%+&($%"#$%##'
@r2324
ACGCCGGATGACCCCTCCAGCGTGTTTTATCCCTGCGAGCATAATGCCTGCGTCATCCGCCANCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGAGCTGGACCNGTGATGGCATTCTCTGGTTATCGTCATCNGGTGAAGAGATTGAGCCACCTGACAGTGTNACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAA
+
:6@=HAE*)77C"D"26:!0#&E8'/*4.!$6($2!-//H.)#H(&"/.>17=FC"=$'<:B>2$*">-674.//A*:09(09DD-"=E0?>/H?H8%/638&6=*8#!0D6>F(@F/;$=9H.+9'43;>2A")A525(5H54D-%+@BC:F7=F+$%@>*//*+0+:$;<H<D/.!10)6+1!==+&-86E<C=45608*B3EC)4A%F"==+6'8"-@7/6-CC,1D/@8.BF$=4;6=F3"1C3-;H(,)
@r2325
GAAAAATGATCCATTAATGGCTTGGGCTAAAATTTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTAGTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATNCGC
+
28-+>691)#<HE72$6D39B=))4.*@8()5B.HB60#GE)-1D8"6B#',A@*D/:6"!A3&'$(5-H:477%,5*9ACB:)BH$'C#$0G36=2#C=38:C=(;0*:&4D-'*H(/"&83GF#<C$C+'&*F?H*=ED2%72E22*0->7?&:)317;:F(A!HDH4(E;#"<#D.64HFD7E4%H3)75%"&'#D*96@.GC+".<5F85<"#=&)5H51791.-=%%+713072>-#@+?8F%&FB/<"#7'F1)
@r2326
CGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTNTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTAGCTGTCTCGCCACACNTNCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACNCCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCANCGATAACATCGCANCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGNCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTC
+
A?G&/48G:H43G%?'=/D1-@>#';20?'1CD!;0()!#%%+A8&9@%*,*B.*E>&$H("(>G.BDB004-"$4)&'"!*;?('9C29!3DC"A'FC53)";B!353F?3.%:#>-<G<C1D6?*452@3?H!F42</2*;((<,,;8#6('FD'5EC$$=A@1><H@/G9"#7E?!@88**C=F.$4'6#G7D<!4B%3=66E5B='E%1-@9*/.,;):ACA@5<=8$A@;8!'?1(G40=+3B/8F-D/C94C3&">0@89H>,;B(7@=5(:/)G00B2,'@608@,)!<E+C9=2<,AGE@E)$@#A>CH),':+,B)4?##&>B/&!$0&91.5G:)-/!+81A9!<C/!0=>23>'!:9!:(%',".;7@6/2%/H'3"0F#9)?A/B$'GB&?$-55&6*@D8B>.&F";6.'(-?+%9=$5!'8A+=<*F/()F&2
@r2327
AGTATGCCGNCTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTANACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTNCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGANGTTATCCCCGCTTCCCCGGATGTGGCGGACATGTCGGAGGATGACGTAATGCTGATGACAGTANCAGAAGGGATCGCAGGAGGAGTCCGGTAT
+
F"+'$!A15A52E@'/@63A,)2C@A$0;4*1$?C&!%$2!3#C76H,:E5@&)B@CC6-0'D?@?F?2:G.FBF=DC5"9H79-HC#+75@*+.B+"/9)&:"21.+?::0):.-4"H;$A;$"$C;<C5$(C"8%BBH4.<*)(09A,06%1D!:/?+5/,5!G=/32!7=B?BE<E8@)$-;6?2A:$!A("%G554-%A:G"@(9>#7/2!-G-(F,9$7%#$07''+&$>@95>F$+<BF*,>2B$;GC))..$B'G/@3*'#6?/"&<0:A#/3,:1"=2G;/8D?*6E4GB#6F!.!(+4E1%*E,/E%"H&/9%28B1
@r2328
ATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACNAATAAGCCGA
+
9DA00F==>#."8'2.4E+:1%E6-044480##!$!$A:+*7#F>,AB'50%C:2>'A<E&*84:D;$H!*/'.+>EA2!HG7G7H?374;%0@2C";&,?($8C#%-DA6!$->D46?4:8E)1#%=$?(!C>5"'A-%<7)6$>EE1"60C=!'9%(E!4(F&43.#6<?#!3)-
@r2329
GGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGAGGCTCCACGCCAAAAGTGAGAG
+
E,"#.!C38,A&$;'+>16,A>A+1,&'+(8)-%/)<G89'-.F1?G!:023&+/=@*48.+$?F:"
@r2330
CGCCGAGACGGTGCTGGGTACGGAANTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGA
+
?*#,/F82+0&/H56F7!G%'>'4B5(A3.(@>!$/$3!13?%+G398D.2:5-4G65<B.$(-;%+7?;0,;3F
@r2331
CAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAAGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGGCTCTTTCATATACCCGGGAGTGATT
+
</#08:9*;2C//,947=5:EADG!4H(+7(DB("H03"B%;200;,5=<<BB">#?().9=8%==5''=GF,*>C,>$/$*#50F9;,?@5E)-%=&;=#D+2C%6F(E>32$;(<;G=#A();0%7)(&+"%E"AC>>"8AEFD8%)(<D.':B),H.C&H0:7=9!)F7?,1H
@r2332
TCCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGNTTTNAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCNCCGCCTACAATGANGTCATAACCATGATTTCTGGTTTTCTGACGTCCTTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACC
+
"?+=,:.C/*4.4G266@#4/E;,D*G):*0(E=!7:C;6"?7?0G"D:#!1"9.HD96B7/>BA18FA&1@:&A+<6@AB!.@)F++.@1CE%EBD'*"6'*<B8E90+D$@&,"%185%'B.;%%<A@FC$<;@-F+H-&H/6'B+#F!"1.7'9+!&,9"+!)3B%6'5'E9-+4;<&A-&.@)FC?*+5$:(%%1>93;D55#<==!!8<28%,B4F4:!:>""+?B&(77:-$$A;2GE*:0'4'=C-.;()7#45+$8.=3--&H<A#;)3DA><
@r2333
GGCCATTGCGNCGGCACCAGGCNCCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACCGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGANAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTGCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCNGCGTATCGATTCATCGGCGCGGGCAATGGAGCATCGAACAAGTTATCGAAATCAGCCACANCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGNAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATNCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATTCA
+
;&#H,'H3&-#.<2,H#)B%BD**0-4&0E@%*;-?C@+@(9;?9"30/+04<90@8)C7=42"7$((*CDAE8!A&#+!*G3%<5%(D9G:,6)+67G,8!(E7+G'?-8(!?:=!*0*EH&E39HD2B%285757<)-4=/C:7((-/2"H(2/F.4'E;!';B9$3E-C1)%.><-/()893*&,%6C87AA2@&HD$0@8(A;=4=?=*2#7D%@:'!.'%8"-A7$/44*8B8<)((1+GD!>$5+3-+$<7&"F(8>-1//;+D/+2)D6(@>:=4&=2?9H.$%H+-F;-FF0:,*8%A,G=G$#(0&,*4*:5(H7$2%(B*F3E&=DE2-G%'D5A-(29:C'8)1*?6>6%F0E72$7?AC<CA;8*#%(4B(G;=.E'F6/0"-325(%=+3.?;4309&/!1G?)%/8-;@F,G;>8$,6=/)*2D!%1"'<%(D9"C/E&,07<>*=4B!/CF'5."4=.G9%64-6E;DGACF7*35G%D(;:07-A6,=:/'7!/<:5A-18->)#%2$2*BA725D5F'.2%HB*,H"B=H$&19&;/*$;/*+;,,"FC%3@>$B:F8"#0&H+#=7=E+?$DA=:G)576HD6EB#$9/*E,7<1!)(GA<'7#*?=)+>
@r2334
NCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTNAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTAC
+
!,*,$A<1B4GF.F*4BE@(@AF">4@E=)9B-+=F!<C)&G+88/C,6/+/?$C,'>-0,&4&2A";.=0+38+;H@0%A??1,%!BH36-"&3,+9;@"13:H'8,66
@r2335
AACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGNATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACNATTTCTATGAGTTACCCTGATGTTGTNATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACA
+
F6#<"F-7A3&&E;8185"$:B8H"HF,FB&@>A-6-9;-'4&'4)!8/*F>)46$?5!HE@+87D>0("A7$/@>9D-%*)<%5%D"H8"E-/C)=#)-**//08B#67E+!1E>E6.7+H6#D66@BF%3.D*/71)0/'H-<"&#9!!%7@?,7H4=@='@2.1(?2!F4EDC/9=D?"G9+;(#7"GD=F"@#60&',E$5,"-'"D:=?7>+:(8HF"D4+C%8%?99D)H6;2=C?%H-75/'8)A+A='.B38439%?G,6@:A<>A1&++;51)HDCC,-46?7'"FG+"3"E*"?/"@61#,8DD#7+#+%3C@7;;C5?A<!*6;?%*E0+<-!'H8!E5#C!C<)%C%!<!,7#*.;$/E/*E#()E553EA/D/:4"."!
@r2336
CTGNCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGNCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGT
+
C8$B#=,:2(?60<&?</622<81D9(!>=:;GAA9H,<1-%,1@?*)$71D:!.+/+()-=FBD5/%<@GD15H)C),%98&@;.28.(4>$//"96;?D?7;6!+=7;+5@3*;?D<#<00%20##;74()$>/$-D((7ED8D21=>*/)"'B8*DA,42#"D+C@:/B
@r2337
GTCCTGATGCAGGGGCNGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGANATGCGAGGCTG
+
E+("=52+H:+9H(5("1$-FA;$HA75%BH"B(E1!#:;8'3'5(19>C7((7%BG6>D9%9@07?>1."-(&,5"5@"3DF04<-@?=;!
@r2338
CTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTCGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTG
+
HH<G%117(C:6=&.%EFD%-#"<4:G#2/G0;+7:?%)(.66+4+F">/=(70&A.-3(@H*='#C=E58B4C1>"6"+@:1(C=%*F.=H("+:+($F0G*09&<!H18'A/(%9+!-*9H)H9,H*C;@;&*B%0!#A3*3'&%6C20$&$;%=@3;:>((>5H5<+42=H#E'G0;DB(G,A)A>>')E,C43@1H+E>(3$$7E:2A*46?"5#@!14+)="H/4+?)>91A?9C1*F<D@@*'H?>=;!($H*8*="56)C"=688C==GH2)%;$H3@#4:0*H(.%>%08>9,(<7,;AF>'"/':?,8E?/F:&FFD)(<9G>,>/(3E-0B7)G9?>02+??80&+@H55B%'$<CA=&2#)"45-6(2;&F@D!.@%E3:"=<2?50;13,4=.=&:3H:841<!;6E6-!50<$0%D)=4C:.0'%G*%.C6?$->?3-:@4+4G!0-005=G='4)&$D8=A$%)$B/2#FHA5
@r2339
GTCCGNTTTTTCGTCTCGTCGCTGGCAGCCGCCGGCCNGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGNATGAGCCGGGTCACTGTTGACCTGCGGCTGGT
+
3B3*<)>.!D;2/F&$$#<0'$,=G+%D2@?8<<A+@<1"$#7<;6*6E0(E9+5>'!*/>A%83$C*'?1(FG!>5F0:"&71#+2'?@(5%?(42E*"5&=-8/!>G*E@5$0E,:D))>==?G,#CA-B0H'*''C27H-H@4(?8!-B>418;'7<.%%-<H>!9-=53@A&9%%7#D/)06!DD@>;/+.27>)B*:HF*/G.4)"'560':65.@7+9+3';<:E(<@%2+$C7*H5GH%""8GD$@0'6%BH>D"B=%@;*:"/
@r2340
GACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTNGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTNGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATNAAATANATTTTTGATTATTATTTGAATCAATTCCAATTACCTGNAGTCTTTCATCTATAATTGNCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAANATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTG
+
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
@r2341
GCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACNGCAGNCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCT
+
BF?F%:>%:-8E./EC%,A;/=*%C"9B2DC;9<1;1/0%=HB>7F3EG<49938<,*A02,8?4<D"!A38D!3(HB=*?/#-2%&80:81&GGG";$HF?#7>DH*"97!)FB-2C1"<=>*D38'HEBH-%4.:21@=?H"?:(40&13B=75&+D%!>/<0C8!5AGD'AB172F/EA*B:+C5+G>)E'5?:.H+/<><-2**+C2D&)B)
@r2342
ACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTNGGCGTGCAGGTGGACTCGGAGCAGTTCGGCA
+
4?.#%2($.9C5((-0AG($/C4;#868A/$B857!0=55>9;,9G*#6D85B"D'D2(*7E2F%97)A*!#FD25>F(04H@3<0=C;:%;3*=8,:5;>'!*6@$2C7)"-F/&5$?-('?-5B'"@)G#!6D9C3!FE7.(G6@*)<6?A";69?&91+8H7(G.ED@0A<*,E;A:-!,D=$CH+;<4$.8*C.5:&3)EB0",(*>
@r2343
CGGCGTGATTCGGCACTGATGAACCAAAACAGCTCAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCCGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGGA
+
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
@r2344
CGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTNGGANAAACCGTTACCCCATTNATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATANTGAGAGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGACGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTTGCCCCGCTGTCTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGNCAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGNTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGANATCNCGGCACTGTCAGATTTGTTCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGNGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTNAAAGGTGCCGGGACCACCCTGTG
+
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
@r2345
GCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGNCAACCTGAGTCAGTTCAGTNAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACAGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAANCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTNNCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGNTTCAGTNGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGNCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCC
+
4&B><8/@+!'(%53$-=':6@/G,?;46B:&A271)#+4@EB,7#@%5#3(.G3"H0=E(=3GH@==,=/6<&4+@5A0-GH0BF3-6H#H"#'>5$&)E/(H?2(E+)CA*<A/&G,+D7!HD)!;=%H'HD;<#7',"?2.8B303*F115/B&3?<,F:/A8HG>&291+;!>H>./<7B>F&;3$6:$+0=H!)>0HE.";-82-BC/:;&4AF..E)D7""A"#"6#<E0B$()3F++6C8<A)&-=DD=+%.,'A('<1+#42+>0.&CA=!5=58#))F(."-.D.#G(=@.6<(%7,/HG6><+9/)1<G:GC/:E2E$$%,H$:5-,%#"2$2C5$A6G,2=2+'B;..#>)"8--'0&-H1C,F9/.A?<&(!@6<),'(3">7!)A@#86'F.!&!&@,H*>=.="<B#<GFC+-.6?.1:!2-8+:B"!@!$5&1B(.)348+C9,*A02)F%219(#!.@:/H9$2@,5%:62B"%6(-G#+;8$01<F@63?)8$/A+C%!/.'$92CA8FG."CH'#B,!%<3??.*GG2!>9-20B0*H8=0)=G$9%=E.0D7AFA='4+&;4>4D!%3-3:;+98$;$(.,B":A)$38+/G)CHCE,550EFF(:>58-(-4<"==1'8--/3@)2=$CA%'+D?)D4,0!C$:=4?;D()0FA*"+2,)#5$+&@H7C/C39$.47D$65+=&4,$;H%&B42A29+1-HA")1F;H)=!G%DF1EFE/&&/2+#9D1-?0)12G,@BFC-B3)+HG2>H5)3=65'"?&?/+DH.FFE>*$""$-1!CE*6E#H;*17+8<-&7A206%G=.))6#+"8&/);'EF)<H,/=C)5.2A>0+#!0-#/E3($+/4=,D8C(0?8>"./2,<A"132>%A39CE6H0B?D"1*E;17&FG!4;H9/*$"C85@/E/9!G&B2!9D4&26<:!+@*+F226"C7'2-3!'E$/H1D*=(2@:#7B2F.G9)/G"(D5*=,49$(G*+F28B"2C.>:59D9GAE0')<#4*C0'?.*-.76:4+D19&-)>EC/07H1>)F?>=:>%)A/<H$7;$C97"!*?"'@<D@28>E'">E<5()/=%>D6&-'(=H0?/?7/%("GE'=,293;%<2B/-%4B7"+%1E,-$%8E%)C/+C+$F>&+F$D508A/C:'<*9H@,"@@B$8?F2)40?;%''62(;9GF://#0/77E;(6*D!%4>%5E?&H>5$%.D%H&0;(-B>.3H12!1B7C+9H?*/BBE)6+HDA3*G6,.6)CF-8!A=E-,5B'H(!H"+"%H++&/?C(F(#E07:C"'.95:.B;=,:6(#26;@>,+<7$F911">H3$5&:9>%96+/&.&!>/1A3E<E#5)B=4><HE++ED<F<E%$4,.+/&=;E*=/83+>:24+&35;8&<.30+F<=*7)F-'-:(%+E84C/*/$=DCHH!F#G*"F)-893.561/&</=&8%5482=(4#A#74=*@+A(+%0$=EA:4DD)5;<7#/7<#>><'?64=FF=*:1HG@<F*&#=5E)E+9%3E<1'5CB0$G5>#+(E30-E#$;+<!=!14B(34BA'H8$33%&,3A<&*:"/0/&0<0A?4?@7H4'%B=92D6:C(0"?@GAC28?:#4F5A%1$7$%+*D5<C?;)?'#B#.B%&BA-2('5B&65.8>+/!B;)2C",=H8;43-."G"<+GF290)#2"%0#1-81:<<33F>,A+&<*2710D">86+$.%2G9=<*62(135*A8H2A?14)F#37G8?E7;*7.1D98.5%1<"F"-=@7@5
@r2346
TCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACCGCCGGACAACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCANATAACGTCCACGCAGGCTCTCATAGTGAAACGTANCCTCCCCGGTCATCACTGTNCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGTTTTCACTTGAAAATAGCCCACNGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGCACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGC
+
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
@r2347
GNCGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGNACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCGCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTNTG
+
%%+')&(()'*&&%*'*(#)%%%!+$"**'!'%"(*+'&&#%%%!*%+'))&*!+*+(#'$'%$+#*&'%%#+("$&)*$&'++%$)('&%"##+#(*"&'"")!*&)&!'(#'%%)'%%(*%%%*"$+!#&"&##&'(&#*"#(*'!)*)#&'#&"$$$)&("%%*#$+*'*&&')%)!+%)*!"*($#*)#!+&%##!(!(!$&%*+)&%(!+*#%!$!!!"#+&)%"""!)*+)#'%&''&*($(%"+#)#$+&$'*))!#
@r2348
TNTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAG
+
"&(+"#)($#+"!#!*%%$+)"%(+!)%&$)*$+"#&!#%)'+"()*)#()!+%)%!&#%+(%!))'*!+*$#'&&&%+#"(#+%!)(+!+'*##%%!"#(%'%*#*"'($$##)*)$#)!#("$#"%(%#"&#"+")%+!(+')%')#)%"&'("'(+&+!#!#*%%)*$)&)#!$&%'+&(($%%'+(*(+*'#'!(!"))(&&+&)&
@r2349
TGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGT
+
9H9%:)2(>+'#1=%E8#?,50.>03/1HF0+:G4E)CD@9%B$4&=B1;%0&982?9B<D=3(,@FF0G+8D2D"6G*8DEA6:%1,H?:$3/5'DFB+-4.HD?+0#D3.7=CF><E?@D9?.%+15<8%9&#/@"6+@9)0+#E-<"B
@r2350
ACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGAAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGAT
+
>01:D".++2D"C8;/F-1A89:6"HG6=?%<H@>)3(479G8B$G&H-'(18=D#)%/3,A8!ED2***H&<(H>FEG8:-?$F;F<*)1,C:,C,5<5.=488BB,D:2#@<=>'A.D98*.<<0DH>":0,/02>(;AFB!/E1A25E*.!!%-4;>1$%=F2C>",&1FFB>$;@</#+(/#93B*:(7-A=2=6626-7@0C@-#0H0==02,:!D+;A.2*A34*$EC"+*?>BF7C*CF%>.',F13>>!5G32*3=!&,F/E&-:7B+>H$#A"+>-9'@9400C&'0G8/<;()
@r2351
GTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAG
+
8!!$G+6(%*5&F#0DF8@H!%G+'&A6:+&(7A.&5H!G&(*6>5<#;(A)H9>?3+2-6/$*=",!>F2+D9/FC$C!12='/B0G
@r2352
CTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACAGTGATAACGCCCAATC
+
+"%+"!"+#+*"(!&+&#%'$%)"#)"('"*&*!%$&*%$"!'')("'++'+(*(+'!$$""%*%'*$+()')
@r2353
CTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAANAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTCCCTCCAAACGATACCTGTTAGCAANATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCACATACCCATTGCTCACNAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGNCATCACCNAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTATTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTNCTAGCCGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATCTCTAACATTTATCTGCATCATACCTTCCGA
+
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
@r2354
GGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGG
+
/,+?/$='%H20GH(BC+DE#)H$$88=2#7*#<&<H6D<%0($3#.#D2%(%>E%$A;5#40GB2!!*F89%.@0D"0<8,B$$04#3!?/:%D1/$.8&0H0?2>4<;G%>3(H$.8E"!4?!7AEA5+7:.9A/HA<27+E:F*,C=%
@r2355
ATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACNCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACACGCCAGCCGTCGTNCTGTATTGTCTCAGGAACAGGATGGAGTTAAGTCGCACACCCACAGTCCCAGTGCATCCGGTACGNATTTGG
+
+>><67/"#2G$78*51)38*-4;!%?3>GD)/@-8$>G6*/"-+@"8">7?=-%)"@?=A20AH$8?E<18B2)H@4&!')GB$46H184";*#BB8#A82FA!6<=/*<=B.?&8D60F>++G557$'B>2*$#:'HF;?"H$AG%*F.F-E'@>:/A-869.,/--6B<8!,9F0:3#>$7.(@FA?G=GAD93%"FA!!$&:,>,,"%6-68H)E;/E%:9342:5>C
@r2356
ACCTGTCAGATTGAGCGTGCAGCCAGTGAATCACCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTGAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATNCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCAC
+
7C7!5/A43*3>G-8!<)>+:"27F"$!#AE+19;9"AA1<76/9,E./B4;-7*(@22B&1+9?A7B(H'581.26>'14:?);4**<438.:7(2;),5-"7H2=D.;F)-66!-"@"&4%;@<C9E6!9F8>%C=2F5C0#"'/&&*$!@/6D,7(?&69<17C,?69F.2E142BC?)C2!4(E)6C%;./B;46D+=D+:*:C/BA"/F<EF6,A@E;6B!%8=E$HHG!EC'#FAG,159<2H:2@=<4&-,;5<>=A6@%0$,-%=6H$4(EG!#"+F5C958-=/8C$,37&/A18E=<!:>%C#3.H/6A97:,(A&/;@0/+CD4-.!(7(#$:2@6
@r2357
GACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGG
+
0D41)GGE<@:9@D71/4!A06DF6(1*02E%BCE885;:FH".B@.8*8=9':?#.:$3(D*F,8*%F@+%
@r2358
CTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTT
+
873DA5*><8.+FB.$1=C=@9>4):5(:2/=+.BD0&!4C+3
@r2359
GTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTNCTGTTCCATACTGACNCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTNATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTT
+
;5H72B*A=E559';1%=C6"1E(&C%:</9F(0-EB!=$>7>%F90!BE,E!)-;+D!,B9.&<2%<28#(4$;9,')=3)==/0GHA*D9#,DAED9/./"4/$$($:D1:F+.8>G7.CG1))0):<>'/#A-'H&0;&(9>*5=(,A*.4#7'*H1>?=%,)"'0=CC3<>6/6A(@6>>4GG(.5"/0E:H1D1BD4?**/G&#!G32*"6!,;$!03F)B@
@r2360
ACAAAAAAGAAACCATTAACACAAGAGCAGCTTCAGGACGCACGTCGCCTTAAAGCAATTTATGAAAATAANAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCANGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATNCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATNGCNAGAGAAATCTACGANATGTATGAAGCGGTTAGTATGCAGCCGTCACTTNGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGT
+
:@4!A*E/$?.<-3-%/$4D78>(-F<2#,G)"@8&!,ED)/%2E.+=5>+?7G@-/-6(*#336F$&0CF)+?7FBD.=(,'68+:/)4:;+9H,!:;///#300;+<2&9<-=1&#F+332!0"7!.B,A8)5(079"(,A1AH0#!F;<6<@B,,@-22$8C-H@%3"7->=)('E<!9'.13&$/?0"!GGCH8/59>#F;*#G)%4=BA(*H4@.#1%/>>?!==5*A-#,)B/;D@CB6(!B28%),2<=G$,-=C4BDF.CHA=80::""G3"7;"$8/F"#)E>EBG,1H6$/A%'/%%C,9#'GF/H.CDA&%H
@r2361
CTAANGATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGGTTTGAGCNCGTTGGCCNTACATACATCTGTCGGTTGTATTTCCCTCCAGANTGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTNAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAANCGATAAAAACGATAATGCAAACTAC
+
)'!%!%+'$+%$#$'"'$%*$#)!!"*+#++#&)!#+&*$)+))!$&"&"*#%'(+%%")*!!&!*#'*!&!"(!(*$("'%+&*"'(*$(#&*%!+"+*%')'"))()#%"&!+"'*"(()"$!$))(()+"!!!*#))%!%($&$"*!'"("()'**!)!***&(%#!(!"#!)(##%)()%#$('$**#"%$("*++%%!(++#!%%&!'"*!"*'()('"#(&*##%+%+
@r2362
GCGAGAAAGGATTATGAAGCGACGCTAAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGNCGATCGTCAGGAAGACAGTGCTC
+
EDC1((.7&!F0<.C=)DH9B"<D2*A>$D7&(1("-08A"8>C:!'=G%:0AH.=A4"!3,/!11F!*0F:446&A?#*29(>=:/#
@r2363
TCCGCAATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATNGCGTTGGCGGCATAGCCGTTANTGCGTACCAGATCGTCTGCGCGGGCATTGCCTCGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTAATAACNGGCATATTCGCGCAGCGATGTCATGCCGTCCNGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACNGAAGTGGCCGTAAACTCCCCCCTTCGTCCGTCTTTCTGTTCTGTTGCCACCCGTTTACCTGTCATCAGGTCANGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATACATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTNCACCATCCTCTTCCTGCAGGCTAGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCANCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTC
+
)(!"&"+)#*)'""$(+((+)+')&''*$%%&")('!%($"#$%'!*"*+%$"#*)!%+*)$%%&*)!"$"%*$**$*!+!%#+**&)$%+"')(&))!+(#$#**&$*&*$($'*('!%$*%&*'(!"'"*#")*%!*$!'#&$)%#")'!&'"*#('%'!+(%&#''""(%#'!'"$&&*)%!)!)&)+"((('!%)!'#%"&*"!%##+')$*&*'&*'+%$)$++!!)+$("*%!#+""))&"!*$'$'")#"#!"+#"*!$+$&$&%***##%))"+&+#%(#$$(#)&$)#'+#+(++)!&!'*($'!$))#*)*#)*$'"&#"$&&'))+!(%"(+('"!!%+!+!!%"+(&)+'!&(#%%&#+!*+#%*"(+"&!)'"+(&#(%!)&*'#*"'(+*"$)&)*$)&!%!$)(+!"('!!+(+%%)(!$#!(&++"%&%&!#!!%#!"*%(!")#)&"++))"!($&!**#*)"*)*%!$#*#&'*#%&&)#+''+&!$*#%#$(%#(!'$#+)%!&&'")&*!(**!*()%$+*#"")+"!$)%&%!&+&)()(!!*$%$)$&'")**#&"%+!)"+)#'')%&*+#)#$$(#%!+%&#''*&''"+#(+&&!$+!*!&#(*!*"((!+(#*"+&"(''"$#*'+*)"(&!!*&+#('++''(!&+!+$#+$!"+("'$+""(!"!')(&*+$""#+$*!'!**$(#'$!&%)!!""&$%'#((+(*(+*%%%''**"#)"++!$('$)('""&%")$!)')''%+()%(+%#*%+((%'#$#)"*$+&""$&+#'("(&%"!)'+
@r2364
GATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATNACACGCCGATCACCCGCACCATTACGT
+
.*:%3)4:5<53=G<=HH8+&#3:$1!5!57,"/79/%<E=3:2,$,3H//D9"$?681%$0DF2(-4B#/'/'?B#&9?:-<"??BC6%>"7<@.CB6.>E6187C+C-G4$(DD%;#"2G%=B+;-068:908-)@>)89E$83,H#$A6E$'2=57$,(!4E*B<<)'<DC60-"=4)+(8&H%3H!51E"1)7'E=$@BA%?.B?<*)&!<@G%/'(?<H&7G'F/HB+0DCA4/
@r2365
GGCGAATACCANCATATCCGGTGTNACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTCGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACGACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCTGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGNATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATNATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGNGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGA
+
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
@r2366
AGGTGGCGCGTAACGCGTCCGTGGTGGNACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGNCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAAC
+
B#29.&;$C6/+3468!9G:%E>,;G4%?6':E.F-#??%3<H3D,57;$>')9!%-11@&)",?<2</@>)D:?-*$H9'?)!BE9-&<5F#'E7?8AC9F&>=<C->+E%FA%/"6AC0A!@3,(F=5H*.DD)$%.B3:%B@E5F3F!2A7D7.>$"'BC.$E)@/&<0/H:.7*7+;%=A(21=1$HC5+GH#1E51:9;FF/ABA!)%>&*A"@3%D29*"F@F(,&778G.6.-B'"/",5>?F(
@r2367
GGGAAGAGAGCGCCACGGACAGTATGTNGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATTACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGNCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCNTTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATG
+
B(F@4855<FD*<0284)8)-94.*;B)"#;2$-?B2@@?@=+9,F"H7$7:%F,*-&!F89)2".!6!(F/53)6083$/:,6)=@#4F++8B&)*%C?A*>5F9*<.24+$H>=3"C6&2:B5<8G7C@#!AG*8(24,@-$-HHFAG8>5<>/(GB22C44FHH:)G""EBA!EF!G(&05!G4+.&1598@'#.?)6$)7E,?:FE>/$(#/-BH-&0.D'E)03?'@&$2:A6H5@1)/=H1&-G<12690GH21A%:=)(+#;=73*G9,"@1+:38G!HD(5F+86,-92-18!2G.F?/",+B>#);;262:&.F/BE..;,,';*#7@02*1.B6>52>C6-H9757?A54E7%!@A2=5:.*!E>HE7;:54>>"B=;DD7(!-#0FH$'2+9($5<2:>,-,':H+*G#4?..8#)##0@D*CA3-:=E).2:;.7+6)@:$F@*?89/BDCCH@'5.(;&,";<"?93=-2(/<D<%2#)A?-",&6G.9-2=*,%+DB$8.>"=0,'09E8>96B0?&";E8G,?H-9C9CC61A!7HH2H;CGG7%90=2D9AG#5.:H)17/14##:6)"D:>C@9<C9'->3(/97E9/=?
@r2368
TCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGGTGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCA
+
*%.()5#(6!>F'AH<59>2/E=22'."263H&H((,<D!@0'(-F/D>$,AAG4;&E719.$4G$C.E-2)H;52B>;0@2'%D->D,&7#'56=)F<A&!=D!>3-<>4.@/@)=50<A+H'03=021=?+!D7?2?E?8%6%$=/1!=C5AD05BE</?H/6+D21*<H6G#'(-9E,D@"@:':3/6:/4/)7:-4?#17<5&C
@r2369
CTNTCACNGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGNGAATAATCCTTCATATTATTATCGTGCTTTACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAANTCTTTCTGTATGAAGATTTGAGCACGTTGGCCT
+
'%%&%"&+$#+#+"%*%)&"+*+&'"'')(#($%!((&&'!#$$*!$'%&"&*&##$'*(*)#(&&#+*(+('))"(+%&'&))%$&()"($!)!")&"+*%$*+##"!!"#$(('!$"""$++(*'"%")"(#*)#%(%#!+!'&&$!(#(&+#!+)+)&+&+''*&'$(!!*&%)*'%#*!$*+(#)&%&%!$)+!*+#"++%!"(!*)&($)#)""(*&%+)!')($"$+"$#(%&'"(*#&&&*('"+$&*$*('(%'$)"'""%&)&$&%$%'!%**"%!#%"!&+('+&+#$**"("$(+$$+$%++)$')$$$")%()#($*')$$'!*
@r2370
ANTNGNNTNTCCCATCNCGCCAGCACCTNATATTCCCCGNTGTCTGCAGTGACTTCTGCGNTCAGGTGC
+
#$#")#(%!(*%#*%)$+('++!*$*+"*&$!%$*)+#))!$$#++"%&+!$+(*#%)"#!%#)'&&&$
@r2371
AGAGCTGTCGAACAGGGGGATGATGCGTGGCNCAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAA
+
7;*$3.:3"5BA)+3B,;B1=:&!FB6C$@:6G)B2</892>%H#9#5&D')$&@8918),32:*'B?":H"%?>-D@8,2;"&51
@r2372
ACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCTGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGNATGTTCACAACCTGTATNCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGNAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGNGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTANCGAATGCCTGTATAAGCTCTAATAGCTCCGCAANTTCGCCTACACGCATCCNGCTGGTTGACTGGCCTAATACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGANCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGNCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGNGTTTTGCTGATGTGCTNGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACCNCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCTTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTNACTCCATATACCGCCNATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTNGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAANGTCCGGCGCACCGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAG
+
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
@r2373
GACCTGCCTAGGAATTGGTTAGCANGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAA
+
1<?/HHH:%F-(07#F3B).)(0+4+1<.-6$-26H"45=HH!5-.G)-+4<E9C31#:<#+B9(.)=8F("'5C-H7.%6D(F>%DA8''75'.'G.
@r2374
CCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCNAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGTGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTANGTAAACACCAGGCATGATTCTGTTCCGCANAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGGAGCAATATGCCATCTCTTCAGCTATCTCAGCATNGGTGANCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGNCAAAATGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGNTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATC
+
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
@r2375
ACGGCGGAATATCTGCCTAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACNTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCA
+
-71F"-H8G#1614<B'G#-$H(+'/:;E%G"4,#D#C/55E:D.,A3+E<@D:-*C00?)9D4'%28E-FA3;6E?740;%4+*&,*E3H@:#$E?1+C)6E+#!FD!(%H5)(>(,CG72<6=B<+'."DB9.;1;>/1A*/)*6)DG5C=(<GH57!&0>!?8:F;3%!A#%(():%:..6,!*00#71D!%7E)&#/$;A7>H3HD?'H2-5G39@-1@$95>!"/7<%G'+$@DE>%+4!/-89B%-:E-,/(6))
@r2376
GACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCAC
+
=F;A.F85=&>-?#9@&.&@D:!H)11$,-?,8G2&.(?E@#3***%50(&8C!39?->31%=*,5H2*<A4H>469FDA5B9?B(C97+"G5<>+!7#%H,>."A8*A(;!B094,*=?'@"#/D;?38
@r2377
ATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTG
+
99$'!5E)$C<(<5%B4&#G=B&/5A;F!4;))#<71;&2#5#B:?9%8.+G1*.'F%>@%-00"*/$B?0(9%+?90);2"/8=$:2EH4=GB=-HF'30.+D)G/!1?DH:$2768/C%<%73>-4!369<90
@r2378
GTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAANCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTATTTCCGGNGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGG
+
.2E54!>#6C)(-%9<?5.*0>)E!.!+=+<6>)@;/B=8(?/78015!C#8'1!8F,A3-!%ED>4H=#4A>)F>A=70)E#1?(",G<D:@B@;A&=%?+,2.1/B)769%,3%-#/A?$D8EE).D*FH.32721:GD?7@-*/'7-B08&H59)+6>F=2C%$30&>7@0E@#!+8E$/<!<.2H(;549(*@50+B8B%2((3C2D<A&1("+0
@r2379
CCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCNGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTG
+
1,&9)&5)65*85H4G(25!C919+5*!6$15<?''3FC&@:62598?:'!&:9G7CH=017:$)C)GB%F);<#%@+!5)>$.E2838+25-F)C(17)C&-3;%7"18H$?#'HE!=A<A?@,@G?0,0DC#341D=6:AB(9)/$>)F<1G&.DGFH3B"C,((#7!$
@r2380
TTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTNAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGCCTAATGAAGACAAATCCCCATTCTGCNATGTGCGAGAAATGACTGATACCNTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTNTTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCANTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAA
+
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
@r2381
AGCTGAATGGTGCNGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCGTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACNCTGTGTTACCTGGCTAACCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCAGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTTATCACTGTGCTGCTCTTTTTCGACGCGGCGAANCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAA
+
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
@r2382
TTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCNAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCNTGTT
+
.0*:<4;!%)F74-;16A2&@<E4B6:F09%#3'.+9:)/)<E)#0,:&E$BG;=!#((H$'1D=EG;?9#+:&3=23167&2A/-7
@r2383
CTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTCAGGCGACNTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCATCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACNACGCATAACCCTGAAAGATNATGCAATGCGCTTTGGGCAAACCAAGACAGCTAA
+
G+7=?5$G:+$6B97<*C1#*8,A6-%*A?G@'71B>1<C5,*F4;6=67"CEF*7./+G)FE717)/>BA=:8</%.>C12$E=!6@<)<)A1B34:-261$F.'F$DG)9:FB3B8/6>7HA4?'3<0,%<0)1E0E5&:3%#9@AH04#=)&A79&>+%'442+7)%.(.),45C=H;E5&FH'*9)".8/*G;>;)3>6,@7=EE'%G/6&=%(<29'8"67//"&-CGA&"5HB179E;B,BB%435.%<F=C'/H8+>-<*2B)@/C?4B;?(!(,@;99/)G#(9;A6*464G(357*#HA8?>C3@B-/!D:27'(#G;(&55=9G<3(3F:(&@#F'F.+2-/,?5E#?#6$-315@56G4*64-(D?>C""=D.A(4>"7.=EBAB!E9DG<,??!7<$)@%<8*"%!C*8C56=-$&<<?($381+8+'"@43&B+D)9'$F:DE!0'8@
@r2384
GCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATAACCGTCATGCGTGATGCACTGGANGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCATCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTNGCGGCAGAAAACAGCCGCATTATGGGGATC
+
<D@9A&?11$G=0:)*/FC$3:+99<53$:36'A(:1+4!!>+*:F;G9&%@!-31+%=-136,<EF;.;;.B5B5?9C:?(A@:C%66/+%=)A!-37*2<359F22.>3HE//()D+?!%$85<,6<6/9363;."0F7)H8-7%<&7CE</&-+9;F4%9G3$HA)A5A<'750!>D3$'.#+%!02=(2@/7H<=/6B>G>!'9'>5)E0E1G*A@$*:>=?F?A14*H>7,88!E;35/67;=,-$A1:<'&(&C"$.F?A-F%<=0D'816*"6B8-#F:<E5=-D*AGA*
@r2385
GCNATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTNTCCCGTCTTTATCATCAACNTNTTTTCTGACCGTACCGCGACTACNTTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTNTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTNTCTGTTGGTACTCTGCCTTGATCGCCTTGTACTCTTCGATAGTCCAGCGATGGCGGTTAAGGTTTGATTCGATTTCGTCTACTGCNTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTNGTGCTGGTTGCACGCCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGNCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTATTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTNTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCGGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTAGAGTGCTATCTTGGTTCCACACTCTGGACAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTT
+
)+&!!$"$#%+#%$#'&+++$()"%!&'%"!!%+%'$#+%)+$"+'*$'%%*(#+$%#)#*$!&"$')(!(%*"%%&!#+!(*!'!%#*+&+&'#&))&%!()*$&+(*'*#("')'&&$"'+&""+&*+'!*+*!("!*)'*&#"(#$#*#%!!(#$"'!(#('&&"&(%+$(&%(%+("&&'%)%#%+$&'$#**'"$!#&&!%%''%(#!$+&$)'!&+"$$$$+*(*%'&&(())'*(*!'$'(!!)*"+#!(')#%+')!%$!"$)#*#*$!%'"))**+$%)'&*%%+**&('')%'$(&+()%!*'''$!)"'%"((&&+$)''%%#)%)#*(+#""((%"$$*#&&*##"+&)!&%$('++!(+$"*'+$)+(&%$++#%(&)()")&$'$#!&$)%&+#)++()&)%%#+#+%$!")&+&*"&)&%$'("**#$(*$&*'(&)!'($)!'%)&&%%%%(%$&%)$!%&!$!)"$#&""!&*!&"&(%(&!#**%#'"++!&$'#(()#)*&(&)%')&"&()&)&%((**%)&&%%'+*#(%&+'"+$+*'''$#)$(*&""("*)!&!'$%"+"&+"*&)+&+'#%$)))+#(#(%(+)'$$***&!##&$(""%%'"%$#++%%*+&%'(&"(+$&(#"$&))$+#('+!)!$$")$"'&"%(%#*+##%)*)+%&$$)&('#"+%%+%%#(%+$*&$%'+"&'!&"")*%+*%$)$+*+!"*+*)'&#&+*+&($&%+!!+"'#*
@r2386
TTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTNATCCNTGNAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGNTCCCTGAACCAGTAAAACAAATTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTNGGGAAGATCGCAGAAATCAAAGCNAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCA
+
;=*/7#+?E;D&;*#DF!"7%2.E@&56A"C&(G,@-@D1C)4*+.$-*HED)1CBHAA/>-$(0,F'$+6>"$&265$3!6%18.&536.17A7/C1')G'<*?6-4G3G%(&G5?+)9;;*#)-4"G8>55HC4&>F@B;!=5.4>2G<B#6#;.0@(GG!1H!E.-,"=@%'(%3CA7@")$**0/3(,&2DG'A-DB@F,8#:=G5:G>G!#A"7.'4)C!$CHB>D-*:5>B6D3"7F3D8<67>@*$-+E'*$#2,374CG9,">1(%67-&HH2$'3-G"@:>D>>+HHB*.8=%G!="?=@;391AC5@.5&8"G7897>/3$!7=)F>2,G+.=H>@>D0F
@r2387
TCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTGGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACNCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAAACGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATNTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGC
+
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
@r2388
GCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCC
+
'1#<$%/'#34)1$=B9)D&-<8"-6-=<5@D75C/E-&(3#DGB?1&7%47C+@@1B,57<=.1C/#,,,C=/*!/638/4BAF/DD,()511@#'4:+D
@r2389
ATGCNTGCATGGAGACAAGACACCGGATCTGCACAACATCGATAACGCTCAATCTTTTTACTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTACAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATNTTTATGTAAAGAAACAGTAAGATAATANTNAACCCGATGTTTGAGTACGGTNATCATCTGACACTACAGACTCTGGTNTCGCTGTGAAGACNACGCGAAATTCAGCATTTTCACAAGCGTTAGCTTTTACAAA
+
(%&!&)++!+&&%&$%(#"*'(*$&&&*"&*'%%')"(*$"*)"("%)%%&")$##)&&%!'*%))"(('*!(+&$($+*"("#$%&%%!*%%%!#&#%#$!$#$!"&%&'')"'+*+%$*'+(&(!('!)""'+'+!'")'#$)'")"'!!%"#"&''*#")'(%"#)(()&)""+")&#)'**&)#"!(&!*#$$"+%(("%#!((&)+("%!+'#*"%+%#(+%&*&+&'!%)&"*)(&**%)$$#%($$%#!%"%'&#+!)+)'!##
@r2390
ANGGTNANNGNAGGGGTACCTGACGGNCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTNACAATGTCCCCGACGATCTTTTCCGCCCTCAGCGTACCGTTTATCGTNCAGTTTTCAGCTATCGTCACATTACNGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGC
+
%(*(%%'!#'%+'&#&#+")%&"%+"!()!$#$*#&""''$$"%"#''(*'%$(##!+$#""+%$+**&#(*($#*$#*'"$**)#)!)))(%)$&'+!%%)+'!+!%+#%!**%"+*%%'!$$%("&"'*"*+!$*"*"$$#*(&)%*%&'$+')&+"$#(&)'(#$%)&'+)(&***($%&'$$$)!'(&*"&!+*'#*%
@r2391
ACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGNAGAGTTCGAAGAGCATCCTCAGNATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGAGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGNGGCCTTTATNTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATNTCGCNCGTAACTAAACAGGAGCCGACTTNTTCTGGTTATTCGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTNTCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAA
+
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
@r2392
CGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTNGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCNTTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAANAAATACAGGCTACTGTGNTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTCGTTAGCGCGACCTCCTGCCACCCGTTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTNACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGNTCCGGTTCTGCTT
+
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
@r2393
GTTATTGCGGAACTTACAACCTCTCAGGCATTTGCTGCATTTATCCTTCGTGANATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCANGTGTTGGCCAGCANGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTNAATGCGCCAGCGGCTGATCANCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGNGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGNCATCCCGGTGACCATACCGTANAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCAATCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTTCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCAT
+
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
@r2394
TGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTNAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAANACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACNCTT
+
%F;88-G9C&G$-A+@0GGF,-A+1'?G*B<$1=)E3=;84><=D?='#C,0>'.%+!('"+(F43BBA*@&314G49+433C>.6)B20"=30?H&35$1D'#)*>;1%;9!88CDA/%HH@&>#"5)AE4(!5<AD"6-%55.(A8=4(<7E/7;)2)59"568+;B.AGC"?*13@*)D"(E*D+.#%"1>.'!B;B">;G2<A>HE8.?D14#F5&3042$8E0HD+2;&7A#(>3.42-'2496A+C=;&#"
@r2395
TCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCGGTTTCTGACGAAACGCCGGGAGCT
+
.5!H)"&@79B6D528;@6.CC2;0C99,:C:,@-3%$0;8!;8(5?4>A'B<#"/E62&C(32C/H:4&<$HC95'#/-.8GD3E4B@4$@6*3>)2+-
@r2396
TCNAAGTGACCAACTAGGCGGACTCGGTAGGAAGCGCCGCCTCTTTTCATCTCACTA
+
*&3C(C3H!),68@<F@E#10C0>5,=DG+H03BD(!#+?348F2DF>D75B/%!H8
@r2397
CGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTGCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTG
+
&%*F@5("!9'CE=*,*%%>@H91/,0'&3D1=='7AH?<2*6C.>=-G6E,+#3HH.*.,=D>.92)*B28)7DHCA97;&H8)4@G15(.(%./(=D5C&(@%H(3B!*GE5/1:"=)0"06':@3@/<DE6F=A;(D501C87)A81A:4+@0.0G#'$9.5?4D&*5
@r2398
GTCANGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAANTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGC
+
=$<FE7&B(.2%270*:E>(0G5#G"035697HG2%.<%/)$;!;6#<F782D2</2"3D:=.?<$4C.$.F6*'&@";1*C2:9..(F0(@#68>F+-C8BGAF<A"$*9>&)@-A28F9+;DH8@>-!+?(?2G@1-94<"';G"5C,#.7FH0H.5C430@$E'EG4;"A@%>'5B677$0C&,H3=5+F1.3)!:&&?F11E>4BD;!?7C6G?'>763-("=9C?2#3E96:F5(C/#;@1=+##H3$6(;!C1:/BH3:7C.,)1'F4)70B)%C!7AF$D/2>0#,<,D;1<5&A:5;+"D67=<3'6C68;D793
@r2399
ATACCNANGCNNACGNCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATNACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAA
+
*$"!(#$')'(&$'(!)+""#%&'"")%#((&!!#*!!$#(!!"%#)%)+&)%+$+&*$*%#+&**!!##$'""*"!*%&*'*$"+*#'$#&(#)!(!*+""*"("+*%$+)(*'&#*)!+$%(&##%)%$#)!%$)!$%%"("#$#('+(#"(!++'&"+"'!'**+*$(++#&**%!"$)()!+"%!(%)**&*!)*%()*+*'*'&
@r2400
CNCACCACCGAGCACCATAGTGGCACCNAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTNTGGGAACAATATGAATTACAGCGNCATCAGGCAGACTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGAC
+
6*64')?+FDE<=0)BB&,4<@7?(C@&>7FEBC$,>3%$"3)%HDB%$9%82A,=;3DE@*?*"'H4AH?GB"2AE=/1,(<085=GA.@>(8G&A88H#'E#D*:FG/'1$D(;9%><2E+>:(<8#F-)9&)C:'=-"==2'8)"06.>1?);F$%H#0=%-.#C!'6(,;HC?@>396"&/6'F3=E$0#@?'F+3);F&-E#%13C72/6A8-4/"C$?96(%/2?$$10#!<)H6AD8E6"H"
@r2401
TCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGNCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTNCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAANCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGNTNAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGANTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAA
+
F<FCH#:3)6!6=B4?2!9+5)94.-1$=%=-1=$;6>#./#!,/G)G7#<-<%F/0)%AG%C:36)1468)@$6>37/&!D!*F&'4E.)7,%++8##5G479+.D&%99.==!D!D!;CC#4HD)H=0#9:H<82<-7,5">9.B?)(%?EA6!@@55-:.?<'=0#;)B>:<7;-@GHA#40/-D51(,H/31FCF,EB48-/$3-H@-1*@7D8%**B36,6$;G(34H!A?1+5@78#";'+,3"/:!.?(D:46<.@-))#H9F':9(G5'/C<?4&&FF?B$DF0?5:1945<GH@@&5@<C+D@9=)%&31E:8F-.(A,!8'@"6;'!H;4)=A780.2=')9HG.DA=.AH.H*:$C1D.CH)79$HEF'>+)&;?+=EC?$6#(*59:FH2@6)8B.=4C;1:4?+5!+<&6*E34)9.2!>!65=FB!C&1+D>'#23
@r2402
CGGAAGTGGCCGTAAACNCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCGGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGNCACGGGCGTAATCTGCCAGTNTTTTCTTGTTGGTTGCTGC
+
-@H';21.4$A4<7!*;8FB$3D;15>'3F"B@)'+%C)7>7.C)H*@B6B(((+%&#.5724*F+:=.'%59D?7F;?&=*0)H9=%0*2./'';HBC.3(6#C37<='H!42$7:*E&:"70"''H?F4)20#FB:A*9:<;>%2C86=HC5"-44CG"7%43;3'7/(.%A&5*
@r2403
AAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTNCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAANCCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATCAACACCTTCGTGATGTCAGCATGGAGACACGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATNTTTATGTAAAGAAACAGTAAGATAATNCTCAACCCNATGTTCGAGTACGGTCACCATCTGACACTACAGACTCTGGCATCGCT
+
!:/4)*5DH>)A>2#-0/.;&.BD16!D%$9345,:'#,'7+5/&2E,)A-0H!,%EDE/0D.18CA56(H@&H(.7.12F36A+BFBE?"BB=!A$,C:640-1)G>)B</%F(04,%B",C4;6CA&#+'622*<$7"2@D%0@C2A'G?'8,C6D7#7E:<-72>="D"A2-H248D'E&"0,+3:F/*8;*'4(/=;B1,0D76A)9AG0:B#?B5-43#"E*F<<3'07@1H,)(5/&<#%/2-*?9$2%3%==<$CC&3C@AA&<0)@#6F,H.<E4G&%)H03,9>=8<7$3/!25%$D(@'/)A7FG(G-9+;2//"859@H64<D@F?5DH(G5,4%5/BF<'C@F3'<E%-$$&?H$<1/%14>5$"C:7,.C;A%)*?<9+?=2-,#;,):>+@7/%%:G@+;.
@r2404
GATACNAAAGAGNNTCTAAAACTGGTAGATAAGACTAAAAATATCACTTCGACAGAAGAATTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTGTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATNCAATGCCAATTATAGATGAAANACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGCTCAGTCTTAAAAGCNATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATNCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTNCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGNTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCT
+
))**"#")(%'$#'+&!$)*!#)#($$)!%("&()%'(!+$!!)!(+'+"$!&'&%***'(!'')&$""%+(!)$(!#*)'")'(#+)*!+"$%*&!'$!'%*+'+!!*'#%"$*%*+#%)$)*&$""%)"$!#"&#$()&("$)&+!$"#!+))&*(**#)++)'$*!(#)!$$$"!$$$&!'$&'**)$%")!!"%#!$$**(+"+%'#!#*!%!$#'$)&(%+#'%!#)%('+'*'*#*#(&+&+!%*!'%*&($+'#$)'#+"$*+!'#$'%%''!)(+'(*+!&'!&!$%"+!!"&!+#($!%#!*$)(+&*'$&%#*%!%!&$&&#"&($*!&""'))$"&&&!"%$!!$'$##"()#&$)&)"')+"*)&$#%)"!#)!+!*)")'))&*+!$+("+*+$!%%%&%!+)+&&)#%%()$'!%*+""(!##(*)!**&()('#$'$")'%'#$))""#+#%")+(+'!+&(+'#+""))*+(%*(&$$%$#)'(%$#+'(%"!")#(")+%++('!!"#%*+'(++'&!+!*&%%)*"!&'%+&(!"(!%**#%%(#+*#"!%$%'*#*)'$")!%'#%&'')'"'&"!+!)*#")#'''+$*))#$"'""!%$&!*&)$!+!$'#*!*$%$)&%**%##*$$#%+'*#+%%*+)+""&$!+&$'$%!)*#$&$"(*")(+#&)&!'$!+&(#(&+))")&&"))!(+"")#(+%#)!)+#)'$!&(&#"*%**!"%)'$)!&%+&)+
@r2405
NCTGNTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAAAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATNGTTTCATCGTTAACCGGAGTGNTGTNGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGANTGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCANGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCNTCCACGGATTAAGGCCGTACTGGTGGGCNACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCCCCTTTAAATGCCGTCTNGCGAAGAGTGGTGATCNGTTCCTGTGGGT
+
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
@r2406
ATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAANCTCGATTACGAAAAAGAAATTCTGGCTAANGCTCTTGCCCATAANGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTG
+
DH'6@F05A01%5'>&&.)4HD&)$5?34'C7?9"C8%DF=&0@*#!1A>-H39!(*5/5&?)&-=&0">'#=#%:5A30#F93#4H=06=@3?:E3!!F(#(:-!E-:GF;2$;G>+-G94('9BG+@>7/>D$H3"GA*27:*=/*&3,:6+>/.A4=,>
@r2407
AAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAA
+
=-8F)(5?,#@(6)"*$1'*E=3C%HC5?57@;28B=-H/5=5$!)49%(-)B<E#D26%6(&C+</!.0HFG2,($,**G
@r2408
ATGACGACTTATTGCCGCNCTGTTCCCAGATATTTCGCCGCGACATTC
+
F>@=<)H:0%=0<1D&16"G.0-+EH'#9/B"CH?&=(G!;==F3&!6
@r2409
GGAAACAGTTACCCCGATCCGGAGCAGGAGGGGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTNAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACNAGTNCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGNGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGNTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGC
+
".)7#:+89A.0CAHF?+"!/&E*F'.@%)*&!8%+A7%1@-/+FEF5)6;C@,9:5$4GHE935%D%@6$)1")<E:.5%)=+1)-0=E%EC*@C7%H>.;(/:/#=!G%E:"F#F2C#)!(#+9)G(+@5-0%;HA8561=?;8$E&0>0*6&</?8,0:"DG+BDDF)#BHE+GBB<4+B5:=-4E9A<"&!&><(F?23:A(%3:,F;D@8(>"*"E56355+'<G,!428&19(&3.!'&?&#F:!/:+A#1G(C71".2%7.@4(1:$8:6="FF1;=221AB4G.9<2GF/&&-@(7-.9+%(:,B,57@.!BE6.BF+$*,F5412+15%&(*-+;#.82,4-'@9H1=",$*6B-)C0%H.CG:C(-8H)-@:;&@)82E'7*G+3)C
@r2410
GACGANTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGGTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCNCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTT
+
CD&=)1:F*71*<H+:+A@":*A)").,GF0<9,5;%;2B74@9GA9(@"#H4)+.2.=)8,&6<:&*=<E3$,09+""A7=5?;02B6!-G2$2+'<<":2*+7?>C?A!1#&6&F<%*(*H"!C&"/,FH2&G6'A/;(EE0HD12*.H3-475/8*A3G1-'/8C1G"&-,4;HAFG.91=G640;GA@,+'7CH''7%/19110"+/2.>&;+C.D"+/B0*'4;;4AF&EE5<8=C;,F.9H62!A>(C+.'A<(<23H"B8?:2?.(H=;G@%1?>8$96;#%$-A<<#?0<=0<)C'$A"5@+C-B!@1.)0+19D?(05A'G,H779<D+-+E1&;1E$/)3-C5<(1=6G'<9F5E#E5//,:/F?2B';.":C#C2:(3B27;9#.@F.:92CE9?GAG=:E!<D@G&2/<B+>%H=/!B;=E
@r2411
AACCNCCNNNNNNAGGTTTTGTCATTTATGGAGCGGGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGATGCTGNGTGTGATCGATGCCATCAGNGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATNCCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTNCGAGACGGTGCTGGGTACGGAAGTGANATATGACACG
+
*&&&()""!')!%#+"!$'#(+%$&!'))&$")"%)!""&(%(*"(%')($')!*)%&&%*"#)$$(&)"#("$#)")&"+&++!!)"$*($("&*!'$("+)'&+&$(('"*$**%$**)((#!!'!*$!*(##$"$!(((%&(*')$+($+$$&+)*$(%*&))%*)"&"!(%*!*##(((&'*'+"'%&*'"""#&)'+""&#"$(&&"!+'%#&+&$&"++(!"!&*(#%$+#*!''+)%&&!(%)%('!+'*')$%%'%##((*(%*"*)$&(!""")%(!!(&()$!!*'+++!(())#'%%*()%$%)%+&&$!%%('))%!#!'!*"
@r2412
TACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGT
+
E;63CE!65'H6&92$A$&@/9E/F*@>A<5H$7-)(4(4?!8EG#'4+&
@r2413
CCGNNGAGATAAACGGCAACTGCCGGAAAATCCGCNTCANC
+
6:2H73);;'A9H.'5>#/8'?40E3E/#9=#/F)+433B<
@r2414
TGACGCNCAGAACANGCANANGGCTCNGGANACGGANCANGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGTTGGGTGTNTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGNGCCAGTGCGAACGAGTCGTGGGCGTACTNTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGNTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGGGCTTCANTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGNTAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCANC
+
%*&&$%(&%%%%$"!("'#%"'(%$$!)(!"%"&"*""$#*$(+!%%#'&'+"#(%$&'$*)*!*&%&!"$!*#&$#++$$!%+#)%'%%'%!"%*!+$++%%*$%"#"'(#)&)#$&($'"&#!!(&"%%*)$+'"&+!!)*)+)%&#%#$''!+#"(&%*(&+**$#"+&#$+(#%%$)(!%#+)%'&"+(%($!)%*+%"(#+&!(*"#)((%($*)'%%"(''(%&*"$)+#*&+'+'&)*%*!+"&+#+"*#")!&''#!#'*!&#"$(("#%+"%"&"%%'')%$+'(*%+'%%'$&!""(+"))'$(%"!%&#&$)#)#$'%(#$#$+%++($%+(%)*)"$"(#%"!'+#"&!)$*)&!*'*$**("&+#*!&$(%"#)"&&(*!%**!#"&#(*)%'")!!&%(($%'%*"!"+*!'&%#!%"+#)'"')"#&)('&**%*!!'(!!&'*)$&$+)#$"$'
@r2415
GTTGCTGTTCCATACTGACTCCAGCCAGAACTNTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACCGTGGGTGTGCGNCTTAATTCCATCCTGTTGCTGAGACAATACAGCACGACCGCTGGCGGGTTTNCCCTTGATTGTCCAGCCTCGCATAT
+
=020E0;AEH?:67-=7B:%,'3-H'%+A$1C/#<,;9D3-(&00G*C:!B<?<(#(6C6+G=B:;('G8"22:G9*-.(A(<E7?)2%12>4(840.C#5@%=9&70(%H;)@?DC&6EF'F27,?A$(>:/07!E"1*<%11%F1C6H/#4D%;EE%B%A2;<A2$!":3F;5-@D)&'*A:15/D@@7%+E6"(*B2&D1'"0,'7+%8HH<*"*<")"225#E7=>H6<5?H/4F-;!+0$"=GD4)/GA&F"/G"(=@/"*E?:/4"33>-:?<)D2C6>$$.;4G3G@C0F+-<+*'-.B5#&A
@r2416
TTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTNTNCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGG
+
'*&.-"G$,50)9$H?F%$A)E(<7>-B%!0HH8E51B"90HG4?!+4=H3#(9D;)?;+!4.(8*%B0/1.B!E)F@@"9%8B'*+D#D=5="7*:)>D042<@-)%+&<!G#A"-4C=,;@3F2H05@E6,&=A*)F#$:-)93#A6<,8'((-H)"
@r2417
AGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCGGGAACGCAACCGCAGCNTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGT
+
/.H>-.1)./A<7F)!2A7!3D-<-9&FB(.D*?8"3@!<0!*4#5)#.!E1H@=%:H;B&!,,-'<6.&--/8D%/-<@;9<)"';>:HBEG39'0*?4=;:5(9*,.:)=)@>>0?21616&60'>HF;/!:2G6;?8A;0E:&C;/#.&#!G8,2"DB122G(4/F!BBC3?*&+&8";@F5:500-%+01?5A>02>1&>(D519(,4&@#",-':<&AA/<@#;4)2+5AH#5($D!3%'%4;96#33.#-$&8():?7%1#<=1*G)2#-9/(.5FA&:/6%DAD/7;A#6):&G-:/C;F7H56E5H;4B+=G6;6B80?);,2F++&0&DB%F7G>%A0!DD9*.-*?(A?%*<2/,B!+,2!56H.?%645)@+C;*G#+#B$G/3/@>C("2!=-C&HC.;47';HD,:!4"4%,6)4B$/=BHF0;3=2&*8H<$;/A778BF<@%93
@r2418
NGANCNTNCCNGCACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCNTCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGNTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAANAGCATCGGGAATAACACCATGAAAAAGATGCTACTCGCTACTGCGCTGGCCCTGCNTATNACAGGATGTGCTCAACAGACGTTTACTGTTCAANACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCNGTGTCTGCCAGTCGGGGGGAGGCTNCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTANCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCATGNTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTGCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGNTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCT
+
%!($&!$$%%!$&(++!((+#($!')+($(+#%*("$)"*)*)'"()'$+"*+*$!$+(*'$*&)#'$#%!&%(($'+!#'$%($%"#!&+)"+!#+*+'#*'$+$&(')+"!)'$*(''#(+'**&$+%++*"+&%!!$%(%"*))"'&**#$+#''"%!(#$$"+&%#&$"&''!)%$(#&#)&$"$(%(%$&$'!*#)#+'&%')#!"*'&*'!"$'#&*$!')'+&%$('($)$'$(($$%#))+")()!(+&)(*+&!!#""##%!&*(#+#&#&+#)&'(#"!)&#'&$"$)(#)#$%*!'$)#')(%)!)$))$')+%("*%*(&+*''*'!+&)(%(*)()*"!((()*')'"'$(("+$*#+"''(&$+%"'("))+""'(&+&%%#")*(&+!#!%'##!#*)+)!"&$"""$+*$+)"#+&")"*&)%*#+*##"(")!*'%$)+")&&)))'&*#!)+#(""$**)&**)##*)%**%$#)%$)'(%#(%#*'#("+&)%)%$&!$($%'$%"(#+'*!'('(%)&+#'*(($*($'$&"!$(*)%$#+$)#%!("%(!!*!%*&%)#!'+#*"'#*')#+(#()*'+&'+!$"#($!&#"(!'))'$&*$!&')'*)$'%%'#(+)!##)%"(++%$(!*#$%')($"'!&$'+%')((''(!)&#+!$"$)'!"#!"+&)%!*!%!$'$+'$))#(*%+!&!$#!#(%"(*'$+$'+%(%'&#%#')($+(&!**$#&+$$$%+&(#%#&!&#(&$$))')&!++**")*%%(**""++(")!#+)#)&"(+*%$$*&#''*'#&*)!+&)#*((+%#+#*'+(%(+"'%)##+$#%$(%*+!$)%)*+)#*"**''#+#''!)&!"$'"%%*("!$(%$)(**)(&#)($$$$$+()'()#'($%&!!'"&!(*(!%#*!!#+(+(()#&(+$*+)())!&&'*'"&&***&!$"**!"$##(#*&'$
@r2419
TTAAGNGAATTTACNATATCGTCCTGTTCGGAGGGAAGAA
+
*+&%$&$#!#(!!+!&*$''"#*+&"*&%)(#$'#$)#!!
@r2420
CTACTCNGAGGNNTTCACGNCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCTCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGA
+
%!)(&&!)%))#&"'*'"#"(*+"+'%(#&!$*($*!&(*#!")!#+"%%'!!%%*+%%%#+)%$*+""*"!**#%($#&&*#)$((&%+*(#""#$+"'')+++(*('"#&+*)#&((%&$&$&!*'(*"#'**#*"+%*"$'+)*)'%$&%'%%%"*+)()+(**!)'&%&+(%#+(&)&+$%))#&%++"!$'&!%"%!!"&*&
@r2421
TGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGNTTTCAGTCTGCNGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTT
+
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
@r2422
AGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCNAGTNATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCTAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTNGCTNTCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCNATCCGCGATGAACCATGAGAACGTCGT
+
F#84=*'1H9(<<?H&-/D,@;#102#!)8C-;A;<)B$?*5E>A48"1D1><>E5<+-5=6?F%F=GB/6;H3;(*-(0F7&FBB32/A!<%#C06'&9%9#2!@+*>:EB,+#2/22B;?A4<HG,F<C='1*=%(E-;*:3>5($G<1%*,3:-%'&8.F='.?5?4@>++/..869?4>CBE7'$#+GC.+2=C(GD(09<1!"B3?3?*/16<)$;,54!C&95/H#:C,BC1(!*C;A/8%8-+8<<>!-$/DFH&2#B7B*B3'%0',)?;,*%.(@0;'0@81A,:<H$CEE)#$B(0@!&85,.C#!E&@96.A(&:<81"!8"C*?9(H1@*?1FB@@D>8B4!>3H226EC$/?B7>B>?9#*D(5=50CF$?=@!2/,E#A0?+80,*?="0.8'H1,1>?:=01=#%!7.@276)G!<1;'6;;!3-B38*1+<1%-
@r2423
GCTGGAGCATNAACTCGNGCTGACGGNGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGG
+
$(#$"&&%*!&**#'**+')!!*$$!)+*"!'*!#$#)!#"'(!*)'#**)$*++#%)&)'*&%!*))'+%&$*%)%%('#%%**(#+(+')+')!!$'#
@r2424
CATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCA
+
%>$054>>408.@&0(=*54H>15*%7;=DA.747C+:5H<D/!@AA<6HEG<)./3H=G">#1H>@3!:!!BC/7*33E@"/3%=#*?3B<=D%#2?$>5)@%$@A=10')&#FG,+)0"H@!+>?DD!<:&'1*$>#(.!A(,4E3;8B5+=A9+3)&!#@1AB:#;=
@r2425
ANACAAATCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTNTGTTACAGGTCACTAATACCATCTAAGTAGTTG
+
'!()!&"+*)!++%&')'!#)**)#'(++"#)%''&(!'!$*)+)#((((&!*'*'"$!$'*##&+''"!*'*&')*&$(#'$(##&*#++(#*+''(#!!$+!((%(+'+$%%*&("&&#*))("""%#'(*#+##!!"(+
@r2426
NAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACNACCAATATCCAGCACCGCATCCCACATGGCTTTCAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTNATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCA
+
!(2:*'/8':$08!GB5-=*B'*",9)C2"7/6F?GB.:20$)6;&G"?+/"/H)#$;6!:G*'#21EE/=+G3,"?+,4GA@;E7373-@3@7@+<B.>.5BC,/4E+3D&:-89")HDH(":C@;$>74-8'*$?!+<*#6*3%&H9B4274$6-8%H#E'"55@>%?.$!*!8&A.':@8>5(@25CH8/8F>61F#3H2ABC@:&?$+2C;4"(.95&,GB@H7:'5+!"64H;1:'(-+)G8:"H.H<1@52("<H0;<9#:E@-66>>!#"7&A5!D866-:<157!"@G;;,!0G=*$:@%%C201.(E%%/C*944.-5H',:8+><,2()#5%?&:13)!9#"71@B&<;4"BF6.54H8ABE**87H!(<@&9G@EDE.%0C1:"@*C$(?8#%<>%5!&94C0(>8%HG(#&14AFF@'?%B,6/5G>B>&EC$)"G!3<'<;D='"2/;D#*CE2+?7%
@r2427
TANAATAACGGGTNCNNTGGAAACNANACTTGCGCTCTCTGTNCAAAACATATAGATGATCAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATA
+
#'#%!%$$%*!('"*!#(&)%'''!)!(*'($'+)"!&)($""&%+'!'!*)$(&&!!(*+#***+)'(#$&*)")*)(!(%"+*)(($)*#%+($&"'"*'''*'%%"()#(&#"#'&$#+)#$%+*!$&$%('!!*"%'*&*#""##&
@r2428
CCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGANTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACTGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGNCTCCCGGACGTCATCCGGAAGATGGNTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCNTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTAACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGT
+
BCA@)#.)"418@?)FG?!C?1'6'G"=!/;?(@;B3#<=HA4C4(+<#6-C4/GA.3!3@7#66*/<C.%!'92",'H*>=4#<,DD.67!<#@""@BA+*4)3DBA/1+=)H=??<*-/B24*B0118!@0"B9H8&26#/,!DA0A%)"+D'5-*6B9>#>;1.=$>@B0-@H!8"&5:6D';1!:'#540$%*'G%=$%;($<5F&E:C6-@/B6,.6%=E*(3/51**;9F%;E&,?5/$A,33/=9@$',%D"6,=D(7DG5H-D8"A>G:."%28!0;,B//2D%)%#-A2/'7'@!7@B30<B3'>(?%963?G!2D4<B)CC:';;H1B%*:31;AH/91'+C:.6,-F:,?B:$@7E<26D$;2&E8A6-6/B(EFB5#H:%>&6?E3<A2!7@D*44;HA8&&61G5'47.)B*16?2?5!20FE5=<C!D6)?(&(7#!@(;24840)/.%B479)#E7H?.)G&;%)1E;D+)D<88&>A1*,E0B!#B@C.F+
@r2429
CCAGCANCANCGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTCCCGCTGTTACCG
+
')#*$"'%(*#*+(%)#$&()!$#'$&+)($&%*&%$+)$#*(&#"'+%**#$+'*))*"#)"'&&(#()&!+%%$&#")!#(+"'*('+%*%'!%(&*&$!(%'+#(**'!(#*#%('#&"+'#+!%""&"+*($"#%&+*&%%"!"+'%)#"("(++('"(#&%#!#%$%%$"('&*(('(!)*$$"(%&#$+*
@r2430
CTTTGCCGAATTATTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCCCTGCGATGCTNATACCGCACTTCCCGCAGCCTCNGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGCCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATNTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGNCCTCTGACGCTTTCGTGGNCGCGGTGGAGGTAGACGTGGCGGCTGATTGTTGTGACGCTGCAGNATTCGTTTCTGACGTTTTCGCCNCANCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGNGCCGGAGGACGCTTCC
+
!+#"(!%%+($++#$#&'+'"*)((('+($$)'#+%$&'+$%**#*&))$!#$*()##*!!((%)#%$"%'#%+$!$$$($!*)%$+&($##*%(($*&+#+#&+!)(*)%(""*#"%#!&"(*+#!'$+%"%(!($+((!%$#(%*+(+"#**"&%($!$)&!+!#"#*#&*#$$""#*(*"%+"+#!$&)(*$%)%#")'*!'"*'!!)*&)+!(#'+(&!%)"%!)&"$'*"#&"*"$%)+'!+'#("$(('+'*'+*)"$(+*%$%("""&"%*((#()!("&''!)!'+)&*+((*#(()*%)+&%+"(+!$$'!!++$'("%)"""))'+!&%'"!'%*(*'$((!%+)("(&$"%#+$"'$'$*&'#('+&&!&%%&))*)("$!)$&$"!%$")$%'!"(+#!!"&$+(!('!#(&*&&+!""(*'$(+*&&+$+(!++#$"%+!'++"((##'#%)*&!%!#'(#)"%%'&%(*)$&%$("&'!((#&$$#"#!*$)$!&&'%('!$*!&'&##$+)
@r2431
GCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATCGATTCAAGTAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAATACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGT
+
9$A%=6);4H"!$*201=<C1=G>7"/!/:'D(HGB$H&.$4#-636,,!BE"'1-@GHE$7=<B2.:+1;""(97C;*-%E17F2HB9+7/H969$E>@C;$?H$*82#HF*+%#4>>!7H0/&58>-<G!1&B+4"HH$3;G,;B8.=)(4<.)#16%D@;"6=>/,B90D/<"F/.A<%C%?.#:4@H21B>C;B:H+243>=$7<.(B$#+,'G"H3/DD-4,!7%0+6F)17FB4?(+/+8A(3$8F-(12AF/D-)*;15A)3
@r2432
CTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTAT
+
#6/:3#:C)H<"(=?8=G<<HD@#D<!+@38('.4+;=5DF!#&9DA/G'%8*B5B-/.HH11A!?8?/-5+:BG(/96*$)F"=FF#0(EG)-3'#C7(+<5C51-7C6D.'?,C90.?&:4A58$>)#@,*,$-A:5G<C:1B=!
@r2433
TACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCNGATTAAACCAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTNGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGCTGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATNCTCCGGTACCGCGCTGATAAGCCTGGTTGNCGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAACCGTGTTCCTGACGGTGNTGCTGAATACAGCGTATGGGAGCTGAANCTGCCGACGCTGCGCCNGCGACTGTTCCGCTGCCTGAGTATCCGTGAGAACGACGACGGCACGTATGCCGTCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACTCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCANACAGCGGGGAATATCAGGTGCTAGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACNGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGCCAGCACCGTCGNGGATTGAGCTGACCCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCGAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGTGAGCGATGATGCGGAANGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACNCC
+
%+'(!)$+)&$'&*'+!"'(#'$$%&*!%*)#%$#*%"%##+$"%**%)$$+'&)!!))'!+!"%"#*')+!%**'#%'*'"*###*("%$"#%""*+$$'')%&$(!(&!"+&#'&'(+"#('*+%()(("%#+(("&*%$+*&&'''$$&%%'!'&'*)$+''+*%*#))&(%)&#*")!&&$"#"&(%"%+'&)!%%&!*!$%&"#*')***+'$+#!)$*!!!#))"*)+!")!$&!+)"!"%##%$))'!$!++"+&+!(*$"!*$'%("'&$(%%*"&)*$))&#)*$!&%*#')))#%'(!*&+%'&$!*%*!"*"+'*$*$%)"&&+(&&)&&*+*&$('*&!!#+$$)*+$%(#++!"+*$*$*)*+"*%#*'"!('!#$)**$$#$!(#!')+!&+!%*$&%'$$'*%*%*()))&+&*))+'*"(++&++!+"#+()'(+#!&$(*"$!!&$!($!'*#*"&#"&%"&"'#!)+!&"'('!$)'&+((#'+"(&$%+)*'#+++'$($)&$##$%("%+'%')&%+)#"'&+$"(!)!"*&""!+*%&*"!&($$"+)!&$!"$#''('%""#'"((+#)'&(%$($#%&&$!%)*+$%%()#%)"'+&()"&+&)+$"(((&"!&&*+#!&))%($+"$+)*''*)'!$!'$!'#&&&+&')*)$"$(&!#$"&*&+'&%*'#&$*%)!"%+%!+)'##+(''$((+#)++*'$(&%&!%)()&%+"+')$+*!'$&'+!)(!((++*'++(*!%&"*+(&#&'!$"$!(!#%+)&#)"((!*%(!#""'#%!%%%*%++*'$"*"("&+%"'%&"''"'$'"+'&+#'!%***'%'(&%*+'!'%("%#"(%$(&'%$$%$$+&%+$+**&+$*&%&()*$#!+#%&*!(('"%%"!#"'$+!#(%%$*&*+'"$$%)"%#$'%+$%!$"(*+$!"#$$(()'!%&!*#*$($*%*&!')!$*&***"!&%#+$&#$+&*"*&#&$'"#"(&#&**%%"%("$&%(%)+%()#''("*!()%*($'&)(")('$#!#'"&&!&#"+$)&)$!%%!#$+&$)%#%%**%+)&+&#+""$#(("&*%")'"%+)"%*!&()'*)#*#+(*)!#%+(#!'!!&&+$*++#"+"&+#"*%"&**"*#"*!'%+(!"(*'!&%%($!"""&$'$"!"#!(**'+$*('!+'$($("&&$%"("$('#"*&!!&'$#*#!""'++!)*)&#((#%
@r2434
NTGGCCANNNTNTGTNCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTTTC
+
$''&&&)#)%*%!'(+&$*$$&!$'"!$(&#"%$+!'+&#$#")!&"*(+")&&!!!)*+%)
@r2435
NGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCNCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTANCAAACGCTTNGCTGNTAAAAAAGCCGGAGTAGAAGNTAGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAG
+
$D9*&.+@6?0#51D@D/0G=FGG3%E+>')9!=62/AF?"!9&(&E,*+0*.1#>HE,665<,&=-0-95;'24'-2-(@814'5#1E(<%,;8B.?G&+@480(1+?0!@*//B>"BB@5:+;>'E4%;@11;8$.0.?"?D4:&0!"A$@+/$2"<A3A%#%!>/?3GF??*4#:3$>.>7)-@D"%&.H6+1BGG1/3BG:(#%=&22B00#1,F+'2243?45B#)@93E:'!;A*"=9=++0D#;%?3
@r2436
TACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACCCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATANGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGTATATCTTCCTTCTCAAAGTCTGACAGTTCANCAAGATATCTGATTCCAGGCTTNGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGNAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCT
+
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
@r2437
CTACNCGGTCAAAAATCCGCAGGCCAGAATCAAAATTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCNTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGT
+
$,=ACD'(G1<'=4?@E!-GE$66A642&#;1G)D!$&,(+,*C9<B:C2<88?F/(&,0,C<+1D/=;%A07H4G9?&7#-0/,E$B>#(0$(25B,&F$*6H,"G(74E2;AC8?5(H5@5(G803#"+$5H83>+/8%;B2=7$$"-B)&7
@r2438
TGCNGATTGTCAAAGACTGGATGAAAACGNAAGGGGATACGGGAAAATGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCNGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTATGGCTTACCTGACCGCCGGCATCGACTCCCAGCTGNACCGCTANGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCNCGACGATGAACAGACGCTGCTGCNTGTGGATGAGGCCATCNAAAAAACCTATACCCGCCGGAATGGTGCAGAAGTGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGGGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGNCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTANGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTNCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAA
+
+"#)")+)+%&%)+$$$$+**)(++!"'%$%)+#)"+%')%*#*&%!&!+#'#$+(%!#(&()(+)!(++*""$$*+%#*!#$*'%&)**+$!&(#(((*!"#(*(%!'*#'$('+!++&#&)&&#*%$%($!+""(*+')&('))#'%$"+#&*+#&('!!(*)"#)#"%%))'%"+$#(%+()+&'*%*!"''(%#)#!!$$()*&#&$#+#$'!!!'%)*+!'!*$%%$*)$%&%*)##&'&*+$!#"%'&'%#++&"&*(&&($"*!#")!)%&"*'$+#*&"#(!!$*)!*$%#(*)*"++$&%+*+#!($$#$#""$#+)(&*'!((%*#%(**))"%%"!%$&'"%+("+()&#!%"&*&)&("+&!!#)##)"*((&"+')'&!"+'!#&(*!#'((")*")%($#!)#$+&)"$%$!$*""+")!&!$))+('&&#$)'!%'(!(#&"!)'#&"))'&)!)%+'*&"*%)**"(%+#%&+&$%!')"'#&#%+#$"')&+$'+'&$()+#!+'"!!%#(##'*++#$''$(+$'%%(+)%!$&$))&'!&#%'"&!#*&)*'"'*"*!"!##$&%%#%#%)!!%")&(+'"#&''&('*'($($)%#+#+#"#+#(&($")&'$$$"&%+')!*"&!#+##)$*"+$'&#)&)&%+'!#"!%"#$+))(++!()$'$*'(%
@r2439
GCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCAGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAACGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACNTGGCTAATCAGAATTTATAACCNACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTANACCTGCACTCCACGCCACTGAGGTANGCCGCATTGCNCTTTCGTCCCTGGCAGTGGTCGTCACTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGCGCCACTCCGGCCATGGCGTACGCNCTGACCTG
+
,5A=3E).4$$=@+6H0.D):->-$<!+-H!.(DHCH1&@"4)!F0H%#)2A.$!A%(.4<'+);3%,7/@E"%C7B.D)'!H=9ABC7#C/B#2>)G!HE5<:GA%H6;C;&+A(<;!><!/94'F169$1C'*C/@4'0$2;1'1,8&&/%D6),,0<$@=21,'!(4%64F&0?A$)(">*0<;//C$=6#.'68+10:*@H$#%/9/%><20/;5#F*$$8&AE=!:E3;250!DEB,F%F<5F:'CC'G%3,"C,:G$93%9)?+4*E'D:=%,C7C,*(.&-H1.$,.!;?;='(.FF??%"4%@)480,3A<3>E?7+'>"0"AC:7"20E(6!!21>89C&;"@%?C+9FF<"6+*/@0(6&2*E@E14*+FA2E9B3!0A=@4<5-+AD>&43-B9!&852%?.D
@r2440
GCTTNNNNANCTNNNAANANNNCNNGTNTNNNGGCNNGNGNTCNNCAAGNNCCTGTACCGTTGGNGGATNNANCGCANNNACNGTNNNNNNNTCTNCCCCGTCCAAAGNGNANNNANTNANNAAANAANGNTNCGNTTGCGGNNCATGCCTNNACNCGNNNATNANATNCNCGNN
+
$$$!"!"!$!"#"!$"$"""##"!!#""$"!$#!"!"$$$"!"!!!$#"!#"!"$!$$"$!"$$#$#!!#!#!!##$!"#$$#$#"!#$!"!"!#!$"#"###"$$!""!!#$$"!#$$#!#$!$"!!!!!"#$$!"$!"$!!#"$""###!$!#!$""#$#""!$$"$""!#!!
@r2441
TTCCGAGTGACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCANATAGCACATGCAGACGTAACCAATATTCGAATTGAANAACTGAAANAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTG
+
:80=#$3$?/+.*DBA0")/9-*17)0G7<17&G3@EA"(<=#5"<7!+-:E%$=",)E?=/E<D:3/G7B,8('7G;,:@%>5@./#*)0G<2<&BD.'1,6!8+E673$'GGGF"A9%5:B!$*+#-/43F:;)*H:,G.-%+#%CF;@;4>(:80177%.(#)8D69+@=C-!=<;B&04;/!:H5G?)%,<FD>*A9?)0+:/B$'
@r2442
ACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCAC
+
C2F%(#A7;@H,+G98+8F"!G.6BBE@4)%B.CF+E;70,F=B(?G!(>'C2
@r2443
CCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTC
+
DA/&5>FF#"B?DA75;>=A&:F!<@*9:/#H3F".E-F"H5"7,CD<A8&H6
@r2444
TTAANTANNGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGANTTTCACCGTGCGGGTGANCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACNGAACACATCGACCGT
+
)#&)!")$$'%(+&"$(%##$+*)%&+'&(((&+(''&"("+*)!)&'&('($'*'!*%!%$(%()(+%()!)$"!+#)&*"#&*$*(&('(&("'!%$&)+&&"+%!&+$)*!()&*%%)#)"%)")(+%#)&#''+''#!+*#)%(($*$(#%*&("+$!*$)%'"+)#+%#+'#*+
@r2445
NGATTTTGCNTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCACGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGNCGTTTTTATCCGGANACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGNCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAANATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAANGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCGCTCGTTTATTATTTATCTCCTCAGTCAGCCGCTGTGCTTTCAGNGGATTTCNGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTCTGTAACNGAGTAGTCGAAAGTGATTGCGCCTACCCGGATATTATCATGAGNATGCGTCATCGCCATTGCTCNCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACNCCGGCACGATCTCGTAAAAACTCGCCATGT
+
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
@r2446
CCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAAGGGAGGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATANTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAA
+
%'8!HF)#,,4B!/A,@$'4GD>-8'H5"">10?.1:D6.E62H2C',/0>C:B-2D7%1E7G?+<,"7*A"'G70A((D29&%4%&32%E=D@F4?-#+9)<HB3H.EB8/5*#&G0"C2!.-6*EG;7D%#0@#->G>H9)&0$8"@H95$4$?-<B6?1;,!4B.>%$<A@4)D-D*A+'(7!G$+?#B9&1@F43;#A6$+E0<EB0(/D#</24C+;8!7(/4B14G537C2%-:5&%17G9"?3#$9;@C-H:+D4#A5&(+0.7"'89.):#%9C;<?::(A&2H;G&F+1$B:B=F*.@&2F'5:H<:;+4396C$2+EGE(:5D?:?3/4:HC&@80;2*4/)5**'4E9BF,),?E.@D,%%5:?C&/F;-/85BAHE3=G>5F8FD85B;57)%5+D><)<H.((F7*+1<5;#(75<=
@r2447
GAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAACGTNTTGTGTACCTTTTTCTGGGTCAGGTTGTTCTTTAGNAGGAGTAAAAGGATCTAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTGGGATTCTTGACTCGANAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCNGGGTTGGTGATTGCACCAATCATTCCATTCAAAAT
+
6'=*.62G"0)6G7<#,'=//=DA-0,0#=<=?,0?5#E''+@F3.5+>#=F.""5(1&/@4190E&/C799=G:,2%09E03E2&1@&!82'/,G7;2F;5G*2*#?8>/DF"%-E%#86:'!#"&?5$D6&+:-8@-/:72D1G/37AH7F.@2G#**0('%1E#9BFF?.5CD2-FF)D/(/D!47=%;DE@)=28!&>1GCGA3D7F8D8!<>/E5)4B:F92E200/E>(7%@0@E(#HBH=+G&3>)2'.+4"75
@r2448
GGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTT
+
H#</>.;GB@%&B$=/5",4'!@2%;D/9GF74)0")+?GE8$&C+&@"@&E)!,(-&9:&255$$2A:7CA14!B>>B5(9B@?G(--%/EH(DB0.8?1H364F5$$;;%B0F/*:2$!G
@r2449
GTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCGATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGANGGCGGGCTTCAATGACCCAGGCTGAGANATTCCCGGACCCTTTTNGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGATGCGGGTNGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACG
+
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
@r2450
CTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTGTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCANTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGNAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAANAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCANCAAAAAANCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATACAGANGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCNTGGATTCTGTCGACCCACAGGAACTAATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTG
+
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
@r2451
NTTAAAACATTCCAGTATATCACTTTTCATNCTTGCGTAGCAATATGCCATCTCTTCAGCTNCCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTNCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATANAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACA
+
$EA&.?B67BGE*@#87@>(9*9.6"-=-0$/'!:%4G()((C)HDC.%@:5-/9''B-7@C8F)9.(%F')#&,E28?77E8&D;:*4)&E"@C!;/G282>D+!8D2*&B8+7F#716/EG.@<.4&H('<'$.=8A;C)+37!CC,2)<6":)7;F'!(+89,%018>@,'206D6B4+53-=57C9=)D%@0/'"880??D@):$0@9%@78+<::G1?!*.G5B0-"-B3?2%*1@HF'3+C.=A;4H8"&:67F($=D;-%G7%%2<E?'*G@=H0%4=D1<0-31%A5%9<7;C>@HF<*"7G>%?2&A)+9<CDD1)0F;1B.@=?#*E=4#!@<DE@D<6E0DE((F-6CF9?#5;6>,,&2E'31&5+/>0C9?'/29#.69=0#$0=;22%00/(<3627',%9;0H*8%3:!-'+@9#3)('3;<>4&
@r2452
CNCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAAGCGTGCCTGTTCTTCGCGTCCGTGAGCCNCCTCACAGTTGAGGATCCACATAATGCGGCTGTTNTCTGCCGCAACCGCTGCGGTGATCTGCGCGTT
+
'12#B4DA$D-"@;?#G8+;)D-&.8C&H2F)"@BA4F!#6)7*1$?AE->CAE347B4;G+H('27>5.B56F4C85$@3F+>H5A8>?F&7&678>E,.D)+*@>2FC?+7+3'%"E/>6!1G=;,$"3)6&FD0GH7B/4;--:E'@
@r2453
CTGGGCNGTNAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAA
+
*%'#&#"(&!'+%!"('#"$%$%'&%%)+%##))##'&))%&)*%"$%*+*#$$$#+*!+)($$#))+')*!$&'(*#)%(($+&""%+"(')''#"&"!+!%%!#!)+''*$+(!('*$'*)*+&)!'&&!#%%"*
@r2454
NNNNACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTGTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAG
+
"#%+*'''$$($)$'&$+++%&$*+())&##!&'(!*&!#+'+'#%+($%"%**)$(+(&!#'!(!(&**!")+#++#'$*$((%+!"'&&%"''($'+!*&+((&&'")#"'#&(!*+(!#)(&++#'$$!&(#%$*'(*)!))(%*%$+$&&(#)#(%&#()'&&#"*&)!"*$%#%)%&)$!"*#++
@r2455
GCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAG
+
;*=+GE%;"A>8"<%@=(:F&1<<D(:#5#'379>170,1*A!355-+'+D13,/773'4*@6@32H885/86&7B12<"89&C$"A0//!CA11@84;"++'6./:%4&<&=-
@r2456
ATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGTCAGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTACTGG
+
1=+"64HD.%A!?-8;650GB&7:=>"<#)14&>D@B&'6=2+F>5+)/(EF",7'2<98.7H#";)@GE2(*.;CD>82H/,EC:>B2)B.,#E#$C9)B9(3F!19FBH;F><+20#0+)/1'(-@6$%#B'B=AF),:('/+8BH)'H:6?&1837D7>-)(H&;F)
@r2457
ATCCATTTCTATACTCATCAAACTGTAGGGGTAGTAATAGTTTATCCGATTTCTCGCNGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCTCNATCCACTATTTAAGGTGATATATGGGAGAAGAATTTGAAGAGTNCGAAGNGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGTTAAAAATCAATGGTGTGGACAATTCA
+
5F<-09BA7&?/(.D24=37*A,:E7>3&#'C9<<FDC:%-DCF4*(F">8.C1@'2?:/E4EEHAD"E?9DFH>1;&1290GG=E<35)(/HE.1H#A=%>-&";.C&(0!@9@=A5-9)&8.2/*"8C*?">%/;>2$=@B;4';(?90BA-*$C872B3%:+B6:@?3&E<H8'.8;0A.<$6!:&"=&8'FE7B?8,C,+6.4C237B91!*+8'3?-,730:4=?>3+"*#DH.$..!=+8597;$!)8';'/
@r2458
CTCTNCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTTAGCCCTGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGCGCCATGTGATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTNTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGTCCGGCTGTC
+
)+!*#!&!'#!$)!*#*"%'!#&(()'(#+'&+"!%*&&"&"#))+()&+*&#%&&#$)$%"&$++%%!&*)))"(#"**)')"!(%%)$&&*!*(*#$&#(+%#"%#+)(+'*#$&'#!!$*(&&#%#&*()!#'%&"&'*"&(+'*#$(*("'&#"#%#("!%#!+'$&%%"(#($(*%"$))'#)!&!)'#'*$#"!'#'$"%'%'!!'+)&%(('*!*'+"#!'+"')$"'*%(%**(**$$"$%*$($()+(*$+!##*"+**()#+#*"&+%()"%)!)#(&%("'!(*&*'"!#*"*'!%$*'!#*#%%"$+*%)(*"$%*%+#')'+#!()!%"'!"&*!)((#%)*'&##'$'%%*(%'&!!'(+*#(
@r2459
CCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTT
+
'73-$G0<H$;>)2/,7%/71B@@?:<6(0%/4!+<:6E;82A-$:<"C!+EADE'A)$5
@r2460
TTTTCATGTCCGGTCAGCANATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTGCTTTC
+
&*+%'%*!+'"*!&#$'!(*)")+$%)'#'*!#%&"))"(!&&*%'*)"%#)"))!"!+"'((+!"%%#"!!+"'++"&!&!&($)""'#'")*+##&!*&%!#)&+*&%$!'#*&'
@r2461
NACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGAGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTNAAGTTTGATCCGCTGTTTCTGCGTC
+
#-H-@+53$,*%'7@)9!/$?3'2@:<%$+0-1&872(9;+EG>,9CB'7@-DD):3"&:D(:-?4<BD7$%/A:+&#DG(G6#033.&3.=1!@,=.<?>?-"3.3?G)/5DA0,=?C.C/74:1+.0C.9E5@7<DC3*'(/=ED$A&:*7>2=5&2>#**H3>4E*#!=F$%'&-27$F'-H&.*-2H07-A";4)E'D53/F<8+>:FD23&7+@)E!(,BEF5.34D;7-G1G3FH!:17&
@r2462
GGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTANCATCCGTGCA
+
F)(#:?57EC)A,+"/8=2%!<0?&")%"F02GD45(1D@'2,?EF,GA/;9ACA-B$.+5<2-D<5%=:*3+9",)"=&=55!&:35>.EF>-94.9AE7,0<E("&'*&>C?'#E5D.B-?+E18C26;B+$,$&(81'+/1?B8C+>!;8F98E*2:2A77BE&->G%)<$A"#E+"(@'79%6359AF)<67F/5#0GCG353,,C/HA/.E8"9<0!-$FEE%-:C0.%C0)##(:F+47F(F:83(%!#E70G-G7'7=EH&*:=:%:,7$G(CC1#?"8&++=D.;19!.$5'4/=C=G(D!;0E1"$E&#(BG>?1/6>D,B<@2"?!(?7!*.7#@@@27G&+C0<-3:6
@r2463
TTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGAT
+
>>?"4D.*:;1:52$#@8&@27%A-&5,$(+1D>$-*($3*0<540"8-+/>FAC)A4&#1G&;=GE8'G"&D@='$.5E=<1CE$/#G.E2$//B1D
@r2464
GCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTNGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGNTGTAATTGCATGTATAGNACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTNGCGGGTT
+
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
@r2465
ATTGGGCGTTATCAATGTTGTNCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATACTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTANGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCAGTCGCGGAGAGTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATNCA
+
++*%%$#*"%#(&++(*'+$($!!!*(+#*#"'#(+"&$"$&&&(&$')#'''!+!#')'""$!##'(&%**!'''!)#*$)'!'+'##((!&$%$)*"!!$&*&%%'*+*!&#*)"*&""(%)*#')(**"*)$*&%*$#(")''##&#'"&$)%""*#*)&%!'$"&!)&""$*'*%+'$!'$"#'"%*!$#&'*#&'**#'(#%$'&$**"$))%*!(#+("+)+*"'+)*#&!&$*(')&'&*&'($#$!'$*%!+&(')!###()+#((#'%$)*"$)"'#!*!"&*$'%*##(+*+*&$'*!!#**"(#!*"!*#%+')')&*$*"%+$'&&!"&
@r2466
AAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGNTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGAGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTT
+
%F3#;<@)526H.D+<$3DEE0C8(/8<G#2(44=,,,<-=>52)H'*D,12+$:.;F4;8<:A;!&@B,33?2B"3-,G'!G=?@;='=&G5CGF=@H&:G=D&0."7E,8&-54'3B?1"<6C$-H?")')B9$=?"5)$339$./:8+*60'6:;<?+)+A"3F6&BE265@E2<9'7G%$&F-%82>6D)(,@3;$-%)&1A03*2(=.(:A7.B662<3"6<3%0;6%+5/2'<&7,F7)G./H@'0E+3'G0/D:>*>)*:92E"<*A*>3!,A5:B$;2'6,>'E1C>&32))82F)$'%=8E@6&H%:&:E(1-9%CEB<CHF7?(9((1-769C)DC/
@r2467
GGGCGTGTCCANATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTG
+
$E9-67")9D3:=0+2;#B/F.5!2>#%12GH1B27>1B.$71)F#9!808E&)>'0
@r2468
CGAACTGATTAGCCGCATCGNGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCG
+
.D4@F$C!8.50*@.E%3>./@H?E+'/H<;%#*%</4%8>#5@D>A5?7+,HH/2:H!1&**5;&7/-:@&#3E9,7?<GC8:=%B=F-F.F#0;B7:C5D/8=#7)&6EC.E>!/#9*!5$3%'6%+GE35%F:85F2:)=<D&'=%(,$83EF!"A%B?CC;.'+*'03%G)HF3@.0@D$2#8$8H&7'=+A.(=+?<2:@DHBB=7<4!,2))?3F821F#ABF)2').9E?*)-A
@r2469
AAATCAAAACTCAACGAGCAGCGTGAGTATTANGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTNCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAATATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGNTGGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCAAGCAGACATCACGAAGGNGTTTATGTAGATGAAGGTATANATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATNATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTCTCTGAACNCGCTACGGCGGGTTTTGTTTTATGGAGATNATAAATGCACTTCCGAGTCACAGGAGAATGGNATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGAAATGGNCGCAGATAGCACATGCAGACGTAACCAATAT
+
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
@r2470
CCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGNTGAATGTGNTGAAGTCTGCCCNTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGAAGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGNTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGNACAGCGTACNGCCCGTTCGCCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGATCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGNCTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATT
+
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
@r2471
ATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGNCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCCATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCANCTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGCTATGTTCTGAGGG
+
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
@r2472
NNATATCCGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTTTACCGCGTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTNGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCNAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCNGCGCTCGCCGCCTTTACAATGTC
+
#%!("''#+%*&+!$))$"+%%!%"&$#'&(+*'(#$!)*$""*##'&"*(**+++(''#(%*"$%(#)#$+$*#++$*''+*+''#)#)"'#!("$)"%&#+(#!"#)%$*"&&!$&+""&%''&*+"&$#"(+#*"+))"#+")#!!+""'%$$*''*'&!%!!)#&'$$$"&"'%''(&)"$*%!*&$'"")+$%!('%(*)%%(++)*(%&)&$"*!+!!#*"!"+*"&*(!$!#!&"!%*)((%$)$("!!'$+*'!#'+)(*#%%%%#*$&*)''*#*$&**&$("(*"('$)!&%"'%##')&'((*#*)(#$#"""&$&!(((#!'')#+"
@r2473
TGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCT
+
@-*G$4&835,<3)F88?7H&??%GAB11,<=21,9B?19?1)3D..%B))6
@r2474
ACTTNTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACACACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAANTTTGACCGTGAGCAGATGCGTCGGATCGCCAACTACATGCCGGAACAGTACGACGAAAAGGCGCANGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGANCGAAGTGAACGAAATCCGTCGCCAGTGGGGTCTGGCTTTCCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCANGAATGCGCGTAGCTCGTCGGCAGAATC
+
:67H?8(B;)/=!>H;=&@%@3G$.6.C3(A&%-1;)A7.3<$C9D8'4=E''!)B--"<'<9@,G="FFE)*7$G35$&0,C/E@@H-A3)256!+-.1H0#$>&2F>,$,*178>%?D2+<:?+"7+$FA.H9<C-&/>@F!/E(4C'<7>2("/$-;;)3D98AG.%4$!@;7:1@D1!638@&*7*-2"HG+&8;BEECBEC+9=!75$0$E?'G>64,FFH897E?'(8>1A#9,0>5"!-%"$0H5/:*(=BG#?BG+9>/5@#7?'4C:B?G<$2'!-FE>!:<34!E:3<72$)H6;6A7@DC4($*?69>,114!G:2+B5,2B/>D97E..0B$B>9(&$*=9*%=4>?'7F)9:*7)5+E&7:$6(,G-,=/)D$#$!1;5,'$A6=$8@4-5&9%B@).0!C0GG:&A23*E/<(D7A<$?G(3)@/8
@r2475
CCGTAGCCACTGTCTGTCCTGAATTCATTANTAATAGTTACGCTGCGGCCTTTTANACATGACCTTCGTGAAAGCGGGTGCCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACANTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACC
+
8*7<?<F""B=D/<!H1B1G@A>7&0./:3H'&;3%78?0.0:-F()3/>4!C=';<@EBA:%,26B9:/&=*C"6<:,.&E7F8*5?26926"5,9F;4#;B%90&-9/3H>1,57=5A7!71:'(E6"<".CAD;/B-;-78@*%.2'7=E%5(+"F7C7+"B('#E2HD'*F+)"!*1'B)9=#384:5&:G9+%A4)=7--G9=&F<:5E,AA@,B9='B+#;#"1;%9<G,!6D(A36*B-1A5-%+9#?D'@%
@r2476
AGCTGTCGCGCTTGANGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCG
+
/%?69F?0.-,'D/&6&70$B50,G<.8"'1(.#2#$!"+/;5(:4=GD:F8;3>3!8)6A562-0,2.?=A;"?/(=E+2E965+&--4HA54B:%2)3!>9?CG>,"B+86E95,DB@*,9-::G.-@:>#$D>A5"83(7;CFH40DA/>%G<!A83%!4
@r2477
AATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTANCAGGAGTAATTATGCGGAACAGAATCATGCCTGNTGTATACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGNAGGAACCATGATTGCAATCCTCATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAG
+
;H>$937%)$13.@+#>'02-EC%.#$H*+5?7-)>#')0<09-G;3B5),@')+-507DC!2&2-F9-;<9=.<%?GE4;@@*H$:#!+);#:>17;&8)>;.1=AC2"C;/C,6BCF*"B(-H8(@:B6/C,+!3.A834?;#<7.$1AFH;&6=!G#C;9(?+,F4>/HGD+5BCAC6;/!>,3;401G;>11E3>E.&.H%C7'2A?)()5,B3D3>:6A&/(E>0(D07<8!D#27;666(@''=;990>**(9B;!FE42-7G<7DF3<@:-=C*<++,F3%H35B>>C3"054%,58:%<*041$)D@'H%05F(:;?GFD<2/9?7ED$)B<<%H,/G4E?###G>90<$5,(,B#A5+@5G>1H(#,2>1;>D-!+'
@r2478
ACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTNGCTGCACAGAAAGCGGGGATTA
+
1./";4.F%@#!"485/>4;.AC>41AB?&D5"=-#5?,D)@5<)0F1B24<B!"7=.7G*H;;66%?5;A.50E*)./C7"/)<
@r2479
GAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTA
+
9.<.E#G8356@0,;,:6)*3B!<20..3?E"G>6!&'/,<-*-7%A17+?),':.@"5<)111425"4.9?;)E1>;%6
@r2480
NTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGNTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGACCCGTGGCG
+
$A0C&#%0),>-..!.,"5&HH#6G#%#8%!F=$<%>47$2=@(E&1"/@>"$1%%H*B:*9%+?'/B>FDA/:5.-!7$B//0!8(447%9B&++C*-:/DFB/4';*GH15,3C%63,449*94'1"A>+5(*+CA>CC@E9.+7DB58>*<9$#G+2%(?!DB),353+*;2>88;21B19E.69?%FG9*+*%>,11:9:63%@:.E!3'D7%<$C7(-.6<':(D@5*>@*'(G0A&:C51D):#!72#EA8G@@&AB;>?8CC!!H!=)3@"04#*;8"&H:*)C3E-#80;E&/46:5&*(5H;F;F'D;3A:))3%2+%+A32A)01C,D5.9$9#!C-6EH/9H+;$!"(G8FA)'>-*9-/('!)=FG+6#E')8F&)@C1-7DHC;5-.-(;6A9*<'&83>)3@.H4C7;!(#",#F-GG$=5*+#A#5#4#61;:HH,9A#2(A0=='BA!:,'->'
@r2481
CTCTATCTGGATAATCTGGAGGCGACAGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGGACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAANGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGC
+
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
@r2482
CCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTATTCACTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCGTACGACCGGAGCCTATCCANTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTNTTCCAGCCAGCACAGAAACATNTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCNACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGNGAAAGCTGCTCATACGAGACACCCAGCCCGNCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTANCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCNCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCANTCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTNCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCGGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCNGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGG
+
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
@r2483
CAGCATTGAGAACGTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCC
+
A)BB>=@!"8/!61:=2B$)D-?E(7)%H(*1.</<918"?<38<@C4BCD?08/B)H+*',A
@r2484
GTNTTNATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTNCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTNATTTGTAAAACCNGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGNTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCNTTCANATGACTCACACCGGTATCCCCGCCCGCCAACGACGGCAATGTANCNGTTTCNCTTGAAAATAGCCCACCGTAAACGTA
+
'"%((!+(+*%+$'!%*!#('!!(+'"$$#)++&)+)$$#!+#+"+!%$'(("*&'*'"!''*$%&**%$(#&!(+#("$''"#!'*+'+*%!"+!+((!+&+*%"'*'*$))(+#!)%*&%(#($)+')'&++"(%)'&")&#(%'%()!!)%!$'&%)()*(!&#&)#'$)($(&!)+*&)%*#!!(+%%$$'(*!!))#%&")!$(&(#(!&)+!)&+(%$#'$)&(+$+'(+%%*#)('#%)#+'$+)(%**$"!+("$%*!&!#'*##+%!%"*#*'"#*%*"+))%+#))+$*#$&$($(+'##)))#(+!#)%$+$#)(%)'#$&'&!"$#+)*+'!'(#&)'$'&$')*&!'&+''%$+*")+(&"()')"(+$"$+#('*+"*'("!"!%#*"&#!%(*%&$#"(+"!))*)%"')!#!!"%'%+(#*'(%$'%)*'!*+(%+'%&$($'#'&'#%%"$'%$!$+($+!'&'+*'(''+&+*+!')&#'(%%*&'+!%!+'"'!(+)&*(&&*(!!$*%+!(%'%
@r2485
CCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTNTCGTGCGGTGTCTGCGGATAAAACAAAAGCCNCCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTNGCTGCAGGCAAGGTCAACATTCCGGTCGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTATTCCGGAGAGTCAGCGATGTNCCTNAAAACCGAATCATTTGGTGACCGTCACGTTTTCTGAACTGTCAGCNCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGACATCAGAANCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACNGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACNTTTCCGGGCTGACGTACACCGTGCTCATCCTGTTTTTCAGCGANCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGTTAATGTGCTGATGCACAAAGCGGCAGGGCTTNCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCNCCGCTNCCCCGGAGGTGGCGGACATGACGGAGGATGACGTAATGCTGATNACAGTATNAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCNGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGGGTCATTTTTCTNGTACGGAAAGTGATGNGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGNGCCGACAGGCNCTGGCTGCACAGAAAGCGGGGATNTCCGNCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCANGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACNGGGGGGGCAGGCGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGNTCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTNCGATTTCAACAAAACGCCGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGNTCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGG
+
):E0:'"HD;&+5>%87.$8CH"G?B<'(3<:/07$#0H2(FA5821;@:3@+&6=%E2E:%17,DE4>8F0*@@:A3!)0"/:!>72+3F"#H%C"9:F)B0FD2,A1B+.+4&'?D-?7-(;?85)*7"1:#-G!"(%"*!$>9,(>!C$70''10BF5B=?'+?A/F1,62C0(/?>"/5A<8C!70"H>)*:=>%=@+2A?BED727('B8#8B--#@+G9G$>"37/.>$E/:A74?:,53"9<#61H8:ED7.A%9!>=79!-E8E0;";%E4*-%))43*5GD<!H8*A?F5!@4;E%E3;*HH2E?=;%6*?+&-E;?76)2&"776A<GF,.#1,H@5E$.5H=-!G<CAA,EE'@+"1,9!7>-*#+B!7$=%7,2"6?':9H4(0-F<1:C#+B&1=-5G7CD0C6%08G*&(CHA8-,$#97$8G))%2/"5/5HGG'C7F6".3,1"<..G!F787C-.'C#*HG25C4-,B7FD91,62%)'@ED44H!7E06B!38,9CCF*<.$$/F(G/:1/4@2)+0!.0=(%/>&4G)B:C3,$96"7@D?/B1;)E?89)CC2832#9#>%A&8+87"30H'30/>4H*4=*.-2#)G&"174G+978AH(3E5?<-$GB(73C8;-'@."*#:7*14/@+G?0GB!*;%.*%868&?/,*>97(@"*%<>;30=.D9:&@'7H2/1E1>>6A2<1@1/2%+D5CC,?,56=.&?<.;"99F,/3/G"0;.>0F;2-=3;=%3@F%",$G<50(;/(7819?;%%/(*"CF>$$7(+86@G)->2<8$HC#0!"%459BH+B''=1*?)4+7<'*9*G4G?#@A<3A>04$68"':9E%8:(3'?D.C0;!+=:(C)>'"?+<0#F57<!9@'F9,%=16%0%#;H'61?6(+)GBB=$AC</505?547-(8&%2FE)(1F$.-4&.6?H6/:+34+F/46H?/#"8.B$*0@#>+E"&/<$4?:5:A'88)C/E,A%"*/?!B#*?2G8(A%G<&.,;*;H//--CDE<G(,,?/8E(BAC'"G2$.B%+/%"0(?)8.%G77'=:%6E4#7G#!;("F$'//,?CC-AC23,2/,G!:&519/(;(9/82D,+E0*<:631366(8&DB.'AF8G+4!C'5/:>84#/$1.?A)09A50&"7<2H=DDH"B+./B<'!"@B&E>C32,60)((&8<@A-$E;,+D).7;@;G?6(&1E/(-,..)2/=%4/*H81%!!*(2:',>D62:;CH=+(>.'C1C,)9A!#8A%73?2@&+D!F%A(A<;E0F4",B,99#0+.D);'.F3.&984BCA@7A7.BB:"9@"=BG;5*0)*5F=,";*52)E"B?G9/*.G8?8!2C0;(')H45A9#/@2*,;4.1C1F(*-5&,/+%C)E00E'H&2(%:31"9,)@@&2$%1>$$+ECF0G/68);'*<A3C%BB%+<#>E&%3#%1->C"50=4E<1&+11533B$DF-;8+#F57A3,4(:DG6C5A$>5);"CG=>;A4*E-E;F>DAG*@;!F$29.60/"@,7,DE8C>>B:GHG87E5:?/.E!2H'?1=+2<H@%")DF7=B='B-/H7,(!2%%*+14E>6=16+8B#!H#,A;($A*<B5=#<!-(2=!2**,,,2.D'-C6G&:F*7
@r2486
GNNTGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGNACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGCCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCNGCCAGCACGTCNGCCGGACNGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGNGCAGAAGCGGCNTCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCNGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGNGGCCACGAATGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCTGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGNCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCNGCGGCAGACGCAAAAACAGCGGCGGCGGGGANTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCNTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGTGGT
+
&"%(!+&(*&"')&&#%)!"$'&$%&+(+*%'%("&)&*%'$'++!%+%!$!+(#!$'("%*+'%'&#$#%%%!"#"$'*++)%!!%+"+)'%'%#!!"#)&&%'#&)(!))&)&$&&)'++"#"%**+)$#!&$#$&%!))$'&"('#+##(&(+%)'!$*+*)##")()#'+&#+'")**'("!)*''%(&*++#++'))'$&+$$""$+$&*(&'&)#)%&%"*&*+&'&)))"'$&+"***(&*!#)%)'#!*+!(%"!'*$#'&$+++!&%("'#)%$%(#'+"*)"!'+'$')&&('!()'*%''"!$#$)"*#&#(#""*((#"%&!(#'+!$*(++)&*))+"&!("!()$()"%)+!*""+'+*&"%!*("####(&&$%'#%$(+)+&"&&#%'(+"&"%(%""")')(%+')&)$&)"#&%!#+$*)"("*&$#*'!'$&+%)&!%("#*!(&***'("#!*%+)&+)""$%'*!"+++)!"*%"$&!*!$&&%$)$$$)$%((#&+#!"'(!('*)%!$#&**"#'$'$)&()###&+&+#&$##'&!)%&#)$%&$$*+*"+(+%'*((!+)%((##+#'!#(#!$*%#!$)'*"(")!!%&'!(+!%*+!)($*%(&)!&%!'*("*!&)'#)$!!"%('#)$$+*!*)$%$$(+*%%!%$$'"+)$$)"&"&"'*!+*%&)*"#%&)'%"#$#))!*#""$!#""#)"(*'#%'#+*$"%+)*!#!"'&*)%)'&")#%&(!($"''&)+!"!'++(#*#%+%)%())*$+&!*%+%!$&+%&''%++)"&+'%#+($&&&))+'*$+!'("%+(#&++"'!(&'%$%")%*(&+)#*()+%&("))())(#)*+'%#(%"('(''$$*'**&'&"(()
@r2487
ACACTCTGGCTGATGGACGCAAGCTGAGCCTCACCGCTTACCCCCGCCNTNACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGNCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCANACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGNGGTGGCCCCCACTANCGGCAGGGTGATCGCACCGGCAAGCCCCCTNAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCNCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCTGCC
+
:)G@EB*&%9,>@H9B@8"&707G7FC(9"==5A?3/#E@-;3374<H;B#1BH/@";'05<5E7:2.0=9)?34+.&8?."5G86#(';7$1D;3-D@D=:<>&;50=B,%68>;6>-<C/63&-;,3EHAG=F%4&2=>/<C.@@9.2+A6B,52G/&>1)##E>9E1($83H$9G#2.*%"5!>=@&<'3;"7EC-$#4;:%%.H9!71G=2-&!*;/0EF@1@EH=)?A,!D?B:+/:4BH85#5D=(@&63H@65)8:H5//>>&;B4-7*;&0GF4C(F%4;)!GH>2'?.0C8/E3*4;HA@AA(D;8$:CF@+($AB)2)1E3"2#A(9:6=)%(,A?7"4752A5;-!>":EC9E(G&"./@7@3
@r2488
NGACACCCCTCTCAGCCGGGAAAATGTGCTGANCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCNCTTCACGCCACGCGGGATGAACCTGTGNCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGNTGTGGCAGCCGAAATGACAGAGCGCGGCCNGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGANGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGNTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGCTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCANACATGAGGAATACCGATTCTCTCATTAACATNTTCAGGCCAGTTATCTGGGCTTAAAAGCNGAAGTCCAACCCAGATGACGATCATATACATGGTGCTCTCCAGAGGTTCATTA
+
!G1%!-"0D=2@F=57"1H$.>'6F#D01&)(?,E/B6H#G4!>E'.</2(6DEHH(&,%!&,G02;42625'1)>9),.@339*B6,A"+5E;-30'8#1/6E$88&9%70-,(E8#-'0.H*2*,:'&$/57>**7"28@'2187;!,2$H""..G9>E7)46-/%3'>B9-,(58A60=72EB2;@@&H3E'&AB7290&6G@7.9E7;14)1H@G9H"+!),.%8*8E&%HH1D4@*8.48(@+G%E;*&)=AA?4G@)H@"7E>=3.0D0?+AH/1/$*!</&";(;H4:'3##'A/G:F7@/<-F5@/07+;'9,C6E"G:0)(H6H>7B%A?'$?<G&E3;AG:F3(CD1GGHHF=->(D/(6#?@03F<'#0D+8A47B;,F!;EA#=%,5).9F3+D*9*5-;?E:/D1?7E-!D+D,&#4?=B'H?,;&?34F;>-9G,FABH@(7C$=17F38/F61%2HAC$(-G2!!!F)@717G*5!9F$863CHA8?!4CC>8>:B$/@4D?;=F%>""87B'11<E4D0%/A4)8;)G+C43-('4@",@(@*("-=>26E#3A#,BF<).&9'D<B3?5$.,@24E'-&4HD.A?."$**72.E#H3F</&'B%D(H@$#($%A%B6=8H-@=B!*?H#"11F'3#78/H:A!5A,&?72&!(?G42,=716?%?-..!.#151%#(B9:G3=6'?6&-AA%23EB0+6'%A9+9GH1-!7!86;B?519+8.BB2&%)!B'!+35D&8E9(>4?B57($E?(8@=5H0>)B,4#7+H5EB"EC&"->=#=E"=-E-%#0#B76;D051*E-G5'6E4F,?E@3(9.#$+F,%$19C<C*'(G:"H7!",=4E>@>FE!;$0C*.!/=F:=0G*,=():5)76:?!;'H"D@!A2%'.+G(8253/66%:=$9C+0!#-3.3:B06;F041>E+2B;>>#-;%;D93<**9C71.6FH%$8%/**;!@;&A,0,F=!8D:G),1'A2F,H'=4;G.49E5>#!5/570,'?%41950C=28&$3B'G
@r2489
TTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTANAGGCTCCTTTTTTATTATTCCCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGATAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGNTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGNAAAACCGACATGTTGATTTCCTGAAACGGNATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCNGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCNCTTTCAGCGGGCCATCATGAATGCGATGGGC
+
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
@r2490
GNTCAGTTCTTCCTNACGGGCGGTATATTTCTTCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGNCTCTTCGGTATATTTCAGCCGTGANGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGNTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGNAACGCGCCCGCGCTTC
+
*"&+*%#%+$*%(&*!!#')'+$"$&"("$!%'*&"&)*&$$(*%($%"$##&$)($)$"**'$*+**+##*#&")(&*"$+'+'%#%$#()'$&"+%+&'$"*&"!*"*%"#""+%%'()((!(%$$!+#$'+#$)"&#(&'(*'&+#&%'$&($*")&'"%#&$#$+)"")##!++""*)'*#)")'$&#!&!&)%++$*%%'*(+*$(++(*%'(&
@r2491
CCGNAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCNCCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGG
+
(!&&+$"*$&((++$!$+(%*'"'#)'$")$'%&+(%&)&")+(%($&($)((&(')!)$"()("+!()%'%)!*##&"(#)&$"&(*#*&
@r2492
GNAGAATCAGCGATTCTGGCGCACGCCCGGCGNTGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAG
+
"#$7!D%F6@<0E06)7-:H2E:,&1F@(&1,:H6*,C#93E'HAGE0C/(HD/2$E#GD%E3"@%(A,1&$46@;2F?-(@="C;'E?"@8)%F2!;,'*+=.(C6A+1H#$"=/&4B8FF-,%<&>&=%.23=C=.&F3D-5=-<;193$=C:7+=&
@r2493
ACGACGCCAGAAGCCTGTTTGANTTCACTTCCGGCGTGAATGTTACTGAATCCCCGATC
+
?..==!D?A(3#(3?0H6=973/2DBAECB,,7D,:)4E9=&3B3)?)*=$EF42CC2&
@r2494
ACNGCCTANACCCGTGNACGAAAGAAATTTACGCNTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATNATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCGTTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGNCTTCGGATTTGCTGGTATCTATGACANGGA
+
#(%*%)&#%%)*&+!%%+&#)%*(("#%!*'"!!++""*()'!$(##''"'%#*+"#%!+&("(##+&'(#%%"!**(**($+!"+))%+*!'(+"!&&$%#$$+()+%!$!!*)**!(&'$&)))$($)$"&$$*#'#(%*&&+("%%)()'%#&&*($''+)"$+!)'%(''$!#+%%!#$+')%#+$+&"+$!%!(*!)(+($%'#+$*%$%++!*!&$%+"$""*)"#&!#&$")#"!(+"(#'$#$!*(%)*%(%%+%)!!"("*"*%*'&)#*+*%)()'%'$)%($*($+*+%)%#!#(!'+#)(%*(")+!"%#(*+%"'#"#%')'&!&!$&%)$$+(+)+)()*'+&'
@r2495
TCNAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGTCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGAATACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGNTTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAAGCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTNCTCAGCCTGGGTCATTCAAGCCTGCCGTCGGAGACTAACCTCAGAAANGAGAGCATANACATCAATTAAAAGTGATGAAGAATGAACATCC
+
%"!%&+$&*"+)!**")++&())!+&*+'$*'')#+&+&()##**")(%!(#)+*&!('")""*(+%!+$+')'&##()%*!#)"$"(#)+#&")+(#'")&(!)#(!###)*!&$+#"(#&$'!')#!")!"%&((!)$*%'))!"&##"+*+#*!(+&*)(#$$$*+!%&$(%"#!!'+'!'*+!'$*+(*"((#%"+"!*)!("+"(!(%'"##*#%"#+'(#)%$#(+*+%&(#*#$+")"#($!$!&(+#($!)!+"''&)!*$%$!&)%()%!*!&!(+("(+'*&%!%))"%"("*"'$"%)+%("+!&*)%('$#**$')%%"!%!$#((+("!#+)((")+))'($))*'+$''%"#"%((("'#)+)%""*+&"'%*('$+)'!$"")&+#($!"(&#(*%)'$%#!*+$*"#%)*+#+!&%$&)#"(%&+#*)+(%$+)$%#$"*$$$$!(+"'"(%*$+)!$(")('#$#"+*++*#*$!$)%($#%'+!$&&$'&#+(!+%&)!('&'(($"!%"*'"+'&("'"##)%*$$()$*!!(*!&'!&'+)#+(#""$#*$$()&'*%""#"!''*!%$$)#*)%"*$"#+""#!%''#(($)!('*'
@r2496
TAAAAGCACNTAAAAAGGTTGNAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAAT
+
*$"(&&!(&&%)*+!%(*""$)'%)$)&'%!#((#**")(')#'&)%*'%(*%%#'*#+(#'$&$%(%&+*(+#"%*)%(++!'(*#$*$%+!++*#$)+$*+!#'''*'"(%"#!
@r2497
AGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCGGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCNGGATGTATCCG
+
;"?<F%??:#-6@B<-1&&&7?C+F;?H;AD64?>)!-><$/#%669=42"@?"=!<!D*'?-/#8/3$1+1,-E+E-AHD)C/8-D.*5=+#9187
@r2498
CCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTNTTACCACAAAGCCGTTCCCGGCAAGGTTAGNAATAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCNGCATCCAGCCAGCGACCATG
+
5<%7"<H2G.G%-/2AH?B,#(#$1..47F6-6F')%$'F7+:=09@B5B=B-2%6;4*AH+@*()>C(E":E+41$110?</.0CA8G70E3;&D=/=F%;5?3/66+-7A@59,0)'!-/?7EF46#</6>B=>#)G=A4*5G!(B(H$%/&9737D0H8<#<=,&@&<C.
@r2499
CAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTT
+
4B'<E/*2*2%0#D?74D#-5#00-#407"/+E"0;!F:'.>0!C7$H(=5=$+>/<>9,0B#<&D@G-/D-09;2ED1+587?1!=B8A9H62/5GD$=
@r2500
GCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGT
+
':/"<05E);5EG@(=.72>A$%&=F0($@.:H'+)@$'A9!-H;)B'$5%7),)C@47#F"=4?H5)"ED&8D6(=;+9%G
@r2501
TGCTTCCTCGGCAACGGCGTCAGAAAATTCTGCCAGGGCGGCAGAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGNAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCTA
+
$G#$&>D:0?E!"8*'.<#)??-E4/E;9:DF.:7?B>""$=@6.*D*6;(7#)<9EHB+1$+7@+1$;1AB!&!?"B<,=0.D9</:BB(25'EG>$7"E(@#1(;.+1+%H8))3A$?)$>4$#48C725@;2+3H>6:$8F0A=6A&+$1537A'!E?9*-1&E1309H.<>+F<B=9!'-*.:9%*>%&&.=%+0F*
@r2502
CATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAA
+
515)@DA!!37/<17B'&&E9FG)!<)BH(+)>)8:4@4@9,<H('4'GG?'@*CDGA/5E,;>B0'=.8,&)<#%<:3*+6=A4A/$AC??.E#460"58@).(+11=F'"*
@r2503
TTTTCAGGACACAAACACAAGCCTCNGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATANGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTATATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCATCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACA
+
$=&H7-30+9G0H:8@>G"!>$=B%F:C)B<>*>B$09*E'=,8#%AD#8/AG@=+C<B!C2;/+"&<?E&;HD7@BF+B$2-D-"4D>=G,;2"-4"E60$2F.2<(&#89%33B:A*=E(3<D57$C&@@-)'9!+@?#ABE+&?HB*)7&)!'3G)G89(0C7"5"(3F+%0!DA!"0H%:A5G+3,4AC0A,=7F1;/%&D5(4&+FC4:3/.D'A$H,E&8HE/:F618?@9=G3@,3B9768A1=2/<G@A.86@)=!+D*.-<EG*>D.871*D5@&0=*#0!BC,2;4?F7>=3!<6-E7(2,/'B2
@r2504
TATTCCCGGCGCGTTNATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGNGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAANTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGG
+
'&7B>!3,;=84H*/*;F!''A+$)EC=1%&9../&%*B2(:BG5H"@9B7"*%A3)$&;"$A0G67>!:#2&+HC,></AB38573=/"BCF+3%B5C8G)G7H3/9G81-&H?7)7*B-*83"B(++)=9HC(6?-2AF.,HE16&5#E6.4E'):C-EG4=A*)C%A#),FCB<H5.$?6,&%+;/2?*('7@3$"-.=+DBE254.6C1#%F:10A?6E)E1,:=)5+=15-6,(,B$7B)A$(,0"74%G@0("<+#7G1"=6),-%//2#8$!?
@r2505
TCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCA
+
/=(<='3"/%F%1/9G!"<6<E.@=482$64B"?/'CD%C.,+D.!:B+5H5G.%>7E=8>#4F>8#:6D!H6-19.*:H4?D,)/E?>*&,C#9G?;4E5+.(4'"*A$G2=+@F9+@A7-*-,2)$C&?D.+3&*#%+280E>3'*>;)".')2F++8:D19&E=948F326G!)4=?'2E<'-=,/2H$2'-B$=7!3C)C(BE*//43/>@FB<$E-(?$&-C><7(GA9D(%=16!9$&*/+>F(0"3
@r2506
AATCAAAAATGTATTTNATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACTGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCNGTCTTNAAAGCAATTGGCGGTGATGTAAACACTATGAANAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACG
+
,BH&D7E+*E6#<)59/5!#,D0D;7/D=$7;90,F-8C//F1D(>+'*&G2,E#F@%<G5.#?#B5H-D75&AA&D10'EEED?C9/+FB'&-;DE=&!B)7==4,/37BF)B6$,$?91).07%3:8-B5,1#'='>B"8G/?CA($*C/;440C=,GB%:-E-()E3-$478"?;@9&CG47=<0B=3-:A%5C*#1=@B.+BAFE?A;,'&3@@C0-<,0!;H.30;:;:"E74G"2;#8:G@&0)(H+(#'
@r2507
GACAAAAATCACCTTGCGCTAATGCTCTATTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGCCTGCATATGTTGTCTTTTACAGTATTATGNAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTGTGGTTCAGCTTTTTTATACTAAGCTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACT
+
0*("8&#3@4D92*"7(%FE)&E7@E*+@<32)(%.+F$938F7,F6(&+!9$8<;"F3-0)EF8$G1&)=.*#)(,@'..+"E9HGC(>0&*2C#B+$A=,($3/5,#;4DH=A6<F448+!%D%<A<,98#?;/7==+H*H8<?3G2;+%()@1+6*@;B7C4E/2!,!A?6%?6'##85(152:2*D17D4B'#</(1,".25.:";''0H,1=%'F!;;;*.9<?7<&6G-@#'5E-,D!1(G*D5;F2)0%D=&;$E-A'AA"C?-<*$D(:;9.6!#8E*6:"1#1H/3+'=4HF
@r2508
ATGGAAGCGTTTATGCGGNAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCT
+
=8!5.<B)D=%D1/;;#&;4#,2+?,/-+4*></699"3.=9-2?+E*-$!:'<'A;D,'67/&"4;H5:F688C59#>E6,$@7F17.7G
@r2509
AATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAAGGAAATTATTTCTAACANTTATGTGCATCATACCTTCCGAGCNTTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTNTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTNCTAATCCTATCTGACCATTATAATTTTTTAGAATGGNTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGNATCCANAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCNAATGTCTCAATATCCGGA
+
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
@r2510
CCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCNTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTAGGACTATTGATAAAAATCAATGNNGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCNGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAACGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATANTGGCCTTTATTTTTGGCATAAATAACAGAATAACCACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCNGTGAGGATATGAACAGATGTCAAACNTCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACNTNATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTNATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCNACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAAGGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATACCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGCGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGNATCACCCGTAAATTACGTGACGGATGGAAAAGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGNTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGANATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACGGCTATTTCAGGAGTTCAGCCATTAACGCTT
+
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
@r2511
CGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTC
+
=8?7H7C"E!2<2A&H7&7<&;..?H/++1B45)*3<0D?H98F6(>-!#*D0256HE*,A*E#H6"?5B1*#;?:!CA"9'C./,?12&>E&7$BE01(6/997'--5F&B=*21"'=1?@C*"G!,,!86,4A3,AF+--7#CD<%8;573@('8%--H;?!+6)<2B)4#GH+?F$.',739$5":<#G*7/AA#)C&%:F0)4,!D:9+7FE677C4A:.C26@')7*60A#?G$&)E!28.*?!E?)!27+.9AB-<6*&<(?H=<4H>&!<H$E-)"9D!;">,#!==1>:8GE%:;C&%,6+D
@r2512
TAAACACCACGCTCNGTGAGACGTGGGAGGCGAAAATTGNCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCNTTCCTGACCGTGT
+
,94#%HD(#:B&!?5"#!,9%&$9;.G'D58*%"@-AE?<)%F@!<9+0DCC/&-G%)1"/720;%$)9BD08!'+D,D=562:1(,):3D;H)<@AA'2$4"*A+8%"
@r2513
AACATTCCTAATATTTGACATAAATCATCAACANAACACANGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTNCGCNCCCTCGTATCACATGGAAGGTCTTACCAATGGCTCTGGTTGNCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTTTGAACTAAAACGTCACAACGTCNCACATTATATTTACTATCTAGCCACAGATAATAT
+
&0?=%550HB(*;<7.>9A20&E-*3F@3?3@<H1$1"")G@/8EH?05;E1.1#@6EA1#(1BH6G9%&&H-D6%5+,-2::E:BD:H;9+!#D.&/2?41+B*321<E9H,*9A:-D266)1**57.1@$=,>0#1!H9F*.#H%C)(/>HCH@)*(2692/,H6;A4!6"=7>A2@0H1$)(7$B2'2%$E?(693::/=%%!.A;-,.5C+H$060:#?<D;=1,%:3#$?F5G61?!7@"G0>"
@r2514
ACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTG
+
,$$)9D2)2A":..A-$E?,+F&?6#.3E425#:%>86C949=22+(>*@:6H:/.0%*$5<$0C%,4;'$
@r2515
TGCAGGAATACCCGCCTCTTTCAATAACACTAAACNCCAACATATAGTAACCCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAANATTAGTAGTATTGAACTTAACGGGGCATCGTATTGNAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCCCTTCA
+
41G/G>/%F,"B!19<;+1(>D<32#"$>"%7H&*+C*-!-F<*D4;<?GFA*5")A%4>;H9+(?<73#)%B0;C5'CCC>>46D2@#2D658F4;.AD7BH6AF:+C/)*<!-,A5B"4,,9')1GH+:5*-B=C<AH@=E+!C98*0H?*8/#B2F-+1+7/5)?EB:8!'+2*A/1DBE31EC1+<@GC%)+E6"A75G.?0B"'CE)*8D@2D,%G%/?/E>@#E4;9B;D9=1$10C.,&/!,0B-A+4@<'!E$/&-&7=ED"-@*'$B$;),&2;:1??B4(!;"66B>EF<0*5@E*<#D##
@r2516
GTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGT
+
E0!=')-A7;&+4-3B584.%&=20B%G$-&E>&=G3G>*2G54H)
@r2517
TGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGNTATCAGCAATGTT
+
:.0%-D-:>6GF9"1-B>.G2>'3<A2$'H+0"!(.C>16/4#E:6H8B55DF#80*!,,--1
@r2518
TGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTNAAACTATTTAGTCTGTGACAGAGCCAACACGAAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTTAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGNTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGG
+
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
@r2519
ATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATNGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGG
+
B74ED'&#7,"*A11F#"?)HD/(>,):G>=*9BC==/6<81GG/+47:HGBBGFH'?9"3A=DEH$D*0$,&(3F5>64,"(5>60C6.1?0AD?2528"837A8<")/D4$802:6441%.7AFCH=,G?%#>@&4<=56!+405G,#/!H2:E"%%7C&C&F4HA#<E/G4@*&8:9/-?5(D)"=2#>?G#7=9<"@2'5128$/
@r2520
TCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCNGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGC
+
*C72*;)029$4&/)=/,8A,&3@4?>3.!;:>$("7#C+2,!@)!!<)7:%D:H*71>!3$(4D8*-97>0::,3A-<*+77580&H:H0C2:;5&@$:5A:)G;2):3"@B+$(#!?0&>DA!3260*,9&5$@("F79!;#6:$FE#/+%/8E*0F:2%ED;?)!27>',1E3@**=2)463"F?%&46A?')$03=@C('C>G;A=C</<,02:-F.A9=>/&EC.6#-00>D?(-D?7('$6.!<'C=B?807?)11&4-/D81'=#12G/,;?#96!
@r2521
CAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGNCNACGACAGGCCCGCAGTTATCAGGTCATGAAC
+
DC(?$=/':453C?G3@5"E/%.6::;4#0BE87'C%G97.#E71$G?9,A@>E'2;.!9!"%%4'7:="';AGF;6!
@r2522
CCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCNCATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCNTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGGGCATC
+
F4>=4G@#"G@,:,B@0@"8*4>>-5@@E0F2?,'EC?<D>$7<&00)4-&CG8")'))+DGD(AH@.BAA)%%!.&C@)?$;6=*B56/,$E=("4+1!26/8*EAD749&@?7B$DB)1E++?@<?'"8><)1?#1<%%8;>2A!>F#)(.,.2@F?#@-5<6G6*#26-3*"6"%'&E%9!<5DH?<E;(3#,D-#9@B8%!"/C=#/2A2!/A=(98@F6#&HG71B,/B+E3A!327D/>#,%:%E!C30D>>6:4A3D75F"DD?E*>$C?78)B0"*583,32
@r2523
AAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGNAATGCATGGTTAAGCCTNAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACT
+
'.'<1CD@27(B.+303>=%-,C/?F..%H+*;$8./2('FA8=?+;B-&6"5)009EB'+>0=-;1GC&*98*17F5@G4.);22C"%1%-$0E31:="B:48DH%*/-/2/?2245G!B:AH#;$-C2+%(G=AC%>49=0H;(.!<$&?$@@H;&+..$7)@F)3.'78F+/7B8FC&$!@"0CB1??0>9F"7<432%&.?<A+B!/EA(5(G:84#*/6
@r2524
CTACAAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTATATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTNAGATGGAAAACGTANGTAATAGAGAGTAACTTTNAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGNGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTANTGTTATTGAAAGAGGCGGGTANTCCTGCAGTAGAAAAAAATNAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGANCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATANAAAATTCAGTCAACTCCCT
+
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
@r2525
AAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATANTCAGAACAAGTCGGNTCCTGTTTAGTTAC
+
)D)D;<77DD-%(68B,>;7F%"4-9317,1E=/1?"2-19?/8C-&GC3FD8H)',,('?,@;#*,@,E;,1-,!D9
@r2526
ATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGTAAATACTTACATATGGTTTGTGCAAACAAACGCAANGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAATAA
+
(H=H2>(5E%.HE&((''#+#'A*763(9,+,G,2D#.#39C/,%%,3#,G7DH$;B8?(B%=8"$;=/?HC".1?3/>)='GB;;&1@&C'##18E+%%!?)&=5!4@;<GB%C%.%)E#1*;&:B/0E=*21.EF#97?:%(8,E"216-!$,?25777>/E>GH*B@1E8&?.@<1"/.!%3BE+8/-B="=7=BB7$5!A<9>+;85.%9<GBE1--5#CD:HB2B:B114!#!"4&A4ED23F'!F?29'/#?D7?296(?8!>A6=,5*%:917)92?F=3C"7=B-/A443+9F7+(86,;9A#8=%#&+@;0$>4)80@D*8,<-0F5,4D!$:?08;E":H.>+G)$2H+(!H)2>(<'2,CHB;>&)D4/71.!,F&'<>&?>B372B./+5+!D2(=!$
@r2527
AGGTCATTACTGGATCTATCAANAGGAGTCATTATGACAAANACAGCAAAAATACTCAACTTCTGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTAGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGNTCTGACCAANCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGTATGTTTGGACCANATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAGGAAAAAAGAAAAGATT
+
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
@r2528
TTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCANATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACNGTCCAGCGACATTCTTCCTNGGTACATAATCTCCTTTGGCGTTTCCCGAGGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCNACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTNTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATA
+
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
@r2529
NTTNCTGCTCTGNNCAATAATATACTTCTGGGTTCCTTCCNGTTGTTTTTGCATAGGGATCAGCCTCTCTCTGAGGGTGAAATAATCCNGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCCCGCAGAGCNTCATTTTCAGCTTTAGCATTAGCTAACTCCT
+
%""('*(*$%!"!!*$$+$)&'!*'&&$&#+"*&"!!&$#*!"*"$))+$')&()&"+#!'%("+"+*#)""!#"#'"(+*()*)'##!'')$$&*"$**#&'$+(!)%%$()*'''+&*!+"&$+"'&!(+(%(&&$*($$(*&$*($)%(**'()*)+#%#($+'"$&)(()!(!$%*"!!"'&((+!%"*($#&)+)"(**!"!+#*%(%$&"#"((%%'*'#"+*!%'$&!(%+&')%$)'(&#%"*('%
@r2530
CACCTCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCACCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCNCGTGCTGAGTCAGTTGCATCAGTCACATGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGNAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGTAAACCGTCAACCTGCAGGATGACACTNTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACC
+
809H6D'2@*0"FA?E5)AE12C*03-/(F):G"388>A=)A*&H"D'D2<3/='499$*H.>:B6))6.@D+&F)<'(@-;6'7(8H(6F<%$D8:C2*?("0(79D=*C49(?H)+?B/G/-C'G7%+<F"C5*A-$5-".*@0,23-%6<=C>D(9#A0<D*:11&11"9!9DF>6;6?$#E.@8E.#8(A*3(2E(90'CE#76:+2F0<?'@4*8#F:,;G2'+H8H9(#?#&>=EAE-+=H01!<&(6A:40:EE$--<G<AHC#8E9258A-31G=$=7=0608(&+:H%H/5!8CD""H<DFD'C)+D:<$4>*/,E0!8B4H;3@$?F4!AG=%=BH'CB93&<8=+-=()&:+<"@?4:*%E(#">>H*&;8*#<+@!G#9)70A;:=3"A</6!@<2/840E,<@&>8#C$"</4<98#'6*:530&%=;.G0D9B$*8?69GB551:<:%&4!:B<B'0(+=>/G;/1F=C@'%E-"0D:.--"09D)&0'.6/6()<0@8:.(A*)&!.?HG..B(;?6;H08@&3.9.0-36?=@27=@G<<"!-':<0@-17);H07%9:(H,B3%=3<E=H.,*5/*:34-0G9=80951%;',
@r2531
TTTCCGTTGTGCTGAATTAAGCGNATACCGGAAGCAGAACCGGATCACCAAATGNGTACAGGCGTCATCGCCGGCCAGCAANAGCACAACCCAAACTGAGCCGTNGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTT
+
+3C)4#G-A:"->+*;A<(;&'7%?*):'F/713-94)9=,B@HHG3'F<?AE5+BC?*:(*8&.%435BH79;>'G%$H2F0F88)!:!<?2C1$%.'*"7*DG%!8:17#9,?DF.!3$34:!)$$#=81&0>5$H%A>.)@5(D8&40!A'C@$0F9HFD$/F
@r2532
GTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATCTGACATAAATCNTN
+
%?AD,G$*9)-G#3;6;%'&#,;B*4H!?;D<0;$/3+)!A7ABEEDD$H<BG03F;"?8.-$H8F?)A@&*E2384@:"DBH0#9)G6E!?@#G
@r2533
GCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGNGT
+
-01:8HB0*78:/@<@C<</%3D%B6-"3*E8(9E<5-1C
@r2534
CTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACNCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTAACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCNACGCGCATTTCCCCGTANAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCGGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGGAAGGGTGNCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGNAGCCCCCAGGACAACCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAANCCGGACGTGCNGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTAAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGC
+
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
@r2535
CCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATNCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGANCCTGTGCACGATTCAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATCTGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACTGATAAGACTCCGCATCCGGATACAGGCCTCGNTTCCGGCAATACTCGTAAAGCATATNAACCAGCACGCTGACGTTTGGCAGTCCGGCGGTTACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGNAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACNTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGTGAAAGTTGCCAGTAACTGGC
+
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
@r2536
TCGNGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCANAAATTACCGTCACCGCCA
+
/(5D>,,E/G*1,GD-9/A!++3)??"%F/9,B1DE=%-@=$3G;&D0A.*':(;?6!1E2+%B<$C24E.?%!H6>#'=(/!=(=)@7G):7<+A7=56'%1#:*8@7EBEF$):C4+."?"078.8A$-50%C3)<0"3;!"E-6CAE4;
@r2537
CGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCNACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCNTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTGACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCNCNACCTGTTCAAACTCTGCGCTGNACTCAACACGCAGCATACTGACNCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAANGATTTCCAGCCNCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGANAGAAAGCGTCACGCTGNACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGT
+
+)&#*+&)+(#*(*"%+*#")$&&+('"$%)+'%#%+"!)+'&$+)#%#"+&'!"!++*%'!%#$(#&&)'$$$*%#!*##&$#"!#)($#%($"()')&'!&$+('+$%!*!$'*"!(#($!(#%!'"%&(*))*#+*"'"(!('*$#%%"!#+''&##"'#$$#!'$*'+((#&!($!$)&+!#("&+%"'()#&*$%&####%"&$$"&*&(&*&#)%*+)$!+'#&&%*+!&&("!*(+$+'"*%(*'$!##'+)+!!++&")$#+(#+*!')!%*)!!#&$&(($!+$$&%&##(($!#+)%%$+#**&+%+!+'")*(*("$&&!+#&'+)()!)&!"(*)$*#)')!)+!$#&*!%##%)$$&+)*$&#$!)#$*&'$%(#'!$&&+'"!!+($$'&")*+$#$"""'+'*%"'#!'*$"!)(#+*+&!(+$#$!&+%$(#('!&($(&$$!"*''#+(%!&((#)"!!)!+$#!!"*+%)(#'+)%+&'%!(!&*%+%$"&+%+(&!"(''!$+(&)%&"%$$!%)&$*+&()*&!""#&)#%#('*'$*&#()*(*$%(!$'%**#+$#(!&%**$$'%#!")#+!#+!')'+!++&%(+("$'"!"#*!!"&'"(#+))&$)+#&&$#%%""+"'#'(+"()"+&$$)%'(&'"!*!("%!+*+$#')$$'"""''(*&"#)'+"*&#"(*$!(')%+#%())&%!+%)'))%'**+(#*()'"(!('"*!!)"('$#"%)+#%"$$%%!('&*#&#*$!+)&&%$+''%)$***!)*
@r2538
GTAATAATTCGNAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTANTTTCTTTTGTGCAAGTCTGACTAACTTTTTTCTACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGTCTTGTTTTTCTATCNTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAAT
+
;)E92C@%+75>FA+H.HG-,(BG"-B:<.476"@$#(!7CA<?1;H%-$&*>;9G)@>E+FF$-B003$$"#;@!F*HA7A5.-G0+/4!31"542B:<?%AD,92E#8G;''$BA?)2!0?@B?0;$)A02"7C6#4).E2'=*G4'!DC%"%3!&9#))C.<9:8B$!C<(#)?H7B"->10#G=8&?91;A497458(FGC$7'4/$?E-A1G,G,&#-,5E+/&:0%:%6*7/89G-35>%:CD9'(>6'CB!ED<#DG&=36?+/6=(0!F*':@4%5#H*"H01&4DFA1<=D12H,FC">$"-,5
@r2539
ATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTNACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTNGCTGAAGCCTTCGGNCTGACCACAGACCAGNCGTCGGNGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATAT
+
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
@r2540
CAACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGNCGACAGAATCCATGCC
+
A66/(6GD"96?7=?@@C2-59)AG31H43!<C*7$*$B8@E;:A3-=#!6:1F/:18">2GC.@E7863A;<C%FH<E$((ADCAAH3*377D"59&H2%C'=*G7)!+CF8,H&9?;.E,'',!D:<
@r2541
GCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAAT
+
CG90:?C7@"7?,;&"($-@><)6&2)%$9/57#G):G..:&8*=B&A&(36?!GGC5>$3+$"D/:$13@)CE':0:E6C-E$5+;%(?()7#;4!#1"!$"!":87-<(3!G%1&;;EG2*<A!C1C&:0C2/;>0A-0DE>C@71@>.$1H-&<D"?<H>!,)8#8C8=67.@=/9**42$6/)%=D0#GE=(/#?D,C/F
@r2542
GATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAACCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTNCTGGGATAAGCCAAGNTCATTTTTCTTTCTTTCATAAATTGCTTTAAGGCGACGT
+
-::HE"F'-+*/7+H,=8.GA<6<0E+<3>"!=G:'$GD&:("5B+&.413.(40>6=-F73!A8(<E!,C=%2AG*(7A$9H4$3;/2H8*'>*=D$DH?%<A'8<D('*/,?D-!GG&-*%0@2#+815/(?+;!8,:G0B@'2%!;+G4%(;BH6&+!>:*#1!D3B"3%0"C,%63!C;>>@:A1E04B%<)
@r2543
GCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTNTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAGAT
+
:D=-57=5A(A:>5B?19$"=/<&64!6&66'"3=&!75#;E=@G>-.DA(A@9'#E-A*'$BH-=BB(D4B;F+)$<?(.91#E:!.4%;7)=3-6,1H88")6+1"?$062BF7>=;!D:B"HFEF<1F,/'<"$'9-6@H>5$5'F:GHA%7,F=&0HF$9,6C7*?F61.1:8,6A940@>&.*AF
@r2544
CGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCA
+
.E>=.-/--8@9G@%07+42!8@0?1"#;$8-1&@:)+?=B8'0+AA7@E($/)3&7@6@4"B6,2."EBF$A4=;*H,3FA0ECED+$=A8HB3&/5.-/HF-74!2'$;>G,<-!;5E**7,4.2!+B(7<=A8;D$$+8FB7,88$:<@.,&(#@0A
@r2545
NACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGC
+
)@4/$))**GH-(E6&E'2#@H6,DF2@.3CAC"'DG1"9$D6+.21+8!B06<!%7B:?&)8*BDB#5$C<,/
@r2546
AACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCG
+
4EADFF0>6$$*/!86<<,B;C#;96</0#/E=C:./";*C@='$$2
@r2547
TANNGCAGAGAGCAAAGGTGGATGCATATGAACCTCTGGTTCATCGAATAAAACTAATNACTTTTCGCNAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGA
+
!#!%#+*(#$'#+!$+$()*&##'&(%**"%(!+!$'"%#$)%%%$'$&#&$*')+$#*!*$%%+*''"'&*)()%+("&%')'"$+()"%+("$$'!+$*$%&"'$)*%!&$*!%#"++(#""+#)'&&
@r2548
AGGCGGTNCAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACC
+
C/2#0!<C!:17=,&611?B#31+5!@22&764(H/7<!(#+,F1-2+G+E84H+$H2%1@:>3?-&
@r2549
CGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACATGGATCCTGAACCCATTGACCTCCAACCCCATAATAGCGATGCGTAATGATGTNGATTG
+
"+((*!'$%&&)#$"$%+&#%#""!&((&#")"*""+)"'!#!#%++!*%%"*($*'(*$$)(#(+"#("))+'%(#+#%!**%"$)'"#!))*'#+'!*$&#$!)*+#$+(")!%&"*)!(++'&&'")&"&(&")"()&%+%'"$$*)(!((%*%+*$
@r2550
CGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGANGACCGGTTACAANGGCATNATCNCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGNTGCCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGNCACGCAGACCGCCGGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGTGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTNCCGGATGGACGCAACCCGCCAGATGTTNGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGG
+
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
@r2551
GCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCNGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGGGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCNGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATNTTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTACGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATNTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCNTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCCGCTGCCAGCGGGAANTACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATNTGGAACTTATCAGTAAACAGAGAGGNTCGAAGTGA
+
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
@r2552
GTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGNTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTNCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCG
+
9"D(@HD7%F#!C=$$/GD!<6B-2,HB#%)3;#2C3.9(AH&%%:C>0F<'&;:5-2+</4)3*B5)1AD.7=1,*5$.>H<DH&&&G.6=@E??)18C>#G62("%#10,/.$;E!4<6%,D3G2F)*!#.=9G:3BF#2G>6"!B3C!7!$A&CBFE$$4C$C1A21<1(!;7-$<H731>C(/;CD!A)>;$E280)49:E?,E3H"1>5B*6/G(8G941)2'%'G%H#3;000$E;0;!3)G(C+8(%$>;A6<1+*,#C"2901%-?2!@F.9-H#6-">5*:?E(F4#'BH)@4+</7/.&6'67+;:A&*6@G,G17!C9('0B"*=2G,6#.G$4*)*?!4"G%HD$8."*@5@C-1)7&;905@;1C<$FB+G:">6"#:)H>A1F3*GE8*+4C5*/,C8:G2#"90/*$,54167D3C/<0E#;/.FH+!9A3F<.8(>>C@?*9
@r2553
ACGTTAAGTTGNTGCAGNTCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTAGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTNAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTNCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGNGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGNA
+
@$F;2+94HD&*-=(011&)/1@>F<D"(?);B;16#;*'9C)H#F%&@C:*,&H4=.7/ACF?6<')3&(7#DH?:1C4;>+3:+)*H@*8-BH>9>%6'G/59FG.H,)&)DFB0B.#>1)BDGD9C,$<*3)8:5+26-B-A6<0#,$+#87<0E#,?%#"%)%;#6%$"''2=7077'F?,:GD3>-B""&3*CBB,&'&"87A>@,%G47573>)GE&4@%$73A+H85.!5)D,@02,0.<4%!:!15-71+8*.)/7/A<E&1,,00!0B$+-D(?'</(!HG?&?$G!+>6!67%7%*+>#@(>"G.A:(1)<8?6F;&<(8G(3=6/H;:+4,1<:B7&"#."9$4)9@.CEA,C>.D1B43FD5*'.(1*:5</0C/3->&B<!F'&4@&75;.3//=*0-!)%&B6&(,,E8@929.(0+E,?(D8A&957EFB>#D2<&?'H,9DH-3B"+3<42#=
@r2554
TCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCNGTAGGGGTTG
+
0=*/B;=&+H(33#(CDC),#(,A'818$G:@&*7FD0*5D/4EB4A3F9!$??HH7G4=43;>,!+E&&1
@r2555
CGCATNNTTNCTCCTGATAATTAATCCTTAACTTTGCCCACCTNCCTNTTAAAACATTCCAGTATATCA
+
!&*%%#!'+$+!&"$%$*&+++'(+!*'*''+$%%!(%+')$$#)"'""%$*!#!#!'!'*+*!'$$'%
@r2556
NATGGNTCTTTCCAGAGGTTCATTACTNAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTNATCAAACTGTAGGGGTTGTAANAGTTTATCCGATTTCTCCCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATANATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGNTGTGATGGAA
+
#))$&"+#%$%&(%!('#*(*$%!$#&&%'%&$#"%!!"+("'+(#'&%%&"!'!$+(&'#'&&)""%($$'*"!*'")$%&#)))+$"#+('*)*"(!$"'()""+$!+$+((+*#+!!#+**'!(+*+$)!+%'!!!)"'$%"('%%#+"%+$)$"!!&*#"$$!"'#$#&%+*!"&+"*#&%'&('%(*+)&('+'("!($'(($+$(*(%+)((!'+*$!*#&('!"&&$"$**(%+&!+'"$(+"
@r2557
TCCACAAATCCCGGCNCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCT
+
AF1D%E1"FBC=0E6*'5G?%F1.21&7;,!59:!'*7,BE1&C&6%/H*<0#F.CH2D0.;/%?8A/4AH%9:G=3;!2<&B:A6!+5&A>4';)A3,D+%-4:EC)E!36891F:1E@>4-).,'"0688#93"-.+@!0A5<&A7,,)&AB6#4.G4G-C;E5,
@r2558
AGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGNNGATGAGAGAAACCAGGTATGACAACCCCGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGNCCTTCCCAGCATTGCCCGTCAGGCTAATTCTGAAATCAANAAAAGCCNG
+
-='8D&/E',,8B,19-!91;?0A94842D6A2CD$7BD=B@F2D3@?A=+F(=#:,8/AD;,A")6*=8!30D4*)0'!$;2F*$,,/4AD@C858F-6D"5>5;#)DD=G'#E;#A$GH>&60/!+2=%"?H=/1BA)7#5-6?:=G9G6"44/F8AE@.-7-"/#,>(C-8F!09.1?@>E76$$%<0;2/1#@487"DF/'#:7B+&</=A183+8G27)7C:6F;0<'//>%7!>9-1@AH)++6"C%#=F1,''!<8D/E*;!E(7=C43,)(A*H54/@4)H31%G@&>=C#;?/=B-*:
@r2559
NGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCNTAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAANACGGCGGTGCCTGGTGCCGCCGCAATGGCCNTTAAACGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACCCCGGANACTGGTAAAGG
+
+9,H#@#.10"*,)(#)2@/4G?8'%D:1.D-<24AG>%GC,!$'=@7@8@&%6FG*D5C!G134?7GB&3;.$6":(&!72<>(>?F010A90"0=#"<.*,D8!'*H*9(32HB5:2=H0*()>39D&%70D9H.@<!ED(&2FDA),3E/8CFHD3?28(4E<F8,<')$A-#F%1GC<3D*:79C?65','1#E?2C
@r2560
NATCAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGNGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATNAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCGAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAA
+
!'#$+&$%%%!"$&(##*!'(*)'**"(#)"""(&!#+("+**")"%(%'!(%"+*&+&&$"''"('+!&+##(*%$(%+'"')+&%)!)*("*&%!&$&##+#"&+&%%%)#(%!"(%**)(&!!)#+#&$$)(&&)$+****&(#()(+())%#*$+"*"*+&*'%+&+!!!*'+#$)$!)+$%+%($#!%&&''!+'*)''*'*++$()"!**"#$#$!$!&+&!%)$#%'&'#+%'*$(#')!((*('")++&)#%))$(')'!$&$)(#*(**"%%'*$)%)'(!)&!$##*#)"%#)!
@r2561
CCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGNGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGTGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTNTCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTCAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGANAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGA
+
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
@r2562
AATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCNGATTCGTGTAAAAAATATGCTTAATAGCANCATTTCTAGGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAA
+
,;=>A$>)2-0#(9.0(*E1"#EHG$0D'G;4.82$%G,?#D(-+-:!7+/'C=0=5)"D=)(<:4B:!09?2@,$20!G+';>?&B01D'(=AH'=,963&-E>)@8@H5+%C-16.H=D"!"DHDF.&0F689F#74>3=>>EA:0%5,4C3(8G%,(F+4'0-.<0?$GD$F-H&0CC-(
@r2563
ATCGTGGTGATNTCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTNGTTATGGTCAGTTCGAGNATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGNTCAGANAGATTGATGTATGGGCAGAGTNACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAANTGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCNCGATGCAAAGTACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTGGCACANGAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCTCCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTNAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCATTTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATNTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGNTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGNATGTGTAGAAAATTAAACAAACCCTAAACAATGAGATGAAATTTAATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCNTGGATATTTGTAACCCATCGGAAAA
+
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
@r2564
ACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCCTNCCGCAAGCAGCTTGGCCTGAAAGACNTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACNGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCAGTACCGTGATAACGCCATTNCCTACAAAGCCCNGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAATGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAA
+
EBG<#5<0:E6B=#8'B<23C>)+6"?H,'.:,$;7=4&;6?)EG&7$!D:5;,94G7E14'1?2=,&.+H=B?%:*'+8"G'#;FG/HE1<,@5:0(FF<=)-#56@?F?2,0F#-,)4&!13*22@*G9/DDCF,G%*F(%6/D6>9/E?09")002,62>#986%>$-+'=*B'3H?E78:C4/$A',;&9812F%&C"H:%$87;<EC+2'&9-7C"B2!$8)C=%7F=0+'1D9$G2+,-C.$:FH:D+)#F5%-/@00E"CBA>&A%(,G!3C$C,/,)$*=&-30:D>8:F15=<:C%6!-4)GE/?CB.:B0E()=/F(B26.2/4)??-"=E/63<.59":7@#87$-B42D+FC$,5G=&CH683(/G+-*HE72"0?),<#)36A1H6**'6"7&>#-?4?;#G/,3"/<//-@61F+-)!15@C5?C$B9#:?*/A#6#(F!&5/2/.D+@9A!27')A/(/GG<!#B1$/&(70@02'8G6)*</.@D6.5<653;$5E8G-=&++2!+G@2#)(=A>*!)GC@<D
@r2565
GTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCAGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCACTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCNTC
+
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
@r2566
CTGTNCNNNNANATTNACGGTCGATCTTCACGNNGNNCTNNTACNANNTNANNANCCNNNCTNNNNNGNNCCTTNNNNCGNTCNNGAGANGTACNNNNGNGNCAAANNNCNGCNNCNNNNTNNTCNNCCNTNNNCNN
+
$#!"!"!!!"$$"$"!#"""#$$$#$!"##$#$#$#"!"!#$!#"$$""!$""!$##!!#!"#!!!!#$"#####!!$#"#"#!$#$!"$$####"!"$$!!!"$#"""$!$!#""$!!$"$"$#"!!##"!!"$$!
@r2567
TTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGGGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTG
+
>4&@>,:DD13=3G6G#D3*HG'=$'5$.(1/C1#!AH15G;B"'"-E->E<<291G(01:HA"E7/793#8H6,A6D!3C4(1,7=#D931#82C/&(80#>@;!-F1=9;;)%+9DH4(0C$>7,-F5D*F#@>6B89BDCBC6*@=4+A5F6C3E+0C58($H8&,3H)A'G3GB0D$<3/#HD$7=3&*/1:+#D&8:@.>G/;GHBGG/)5F"HF,('HC3$@-+21/H*A>.,/412$3EH.:0%6?A=H&B-A)5!958HG3,;"'G482:E<B#E60BDH6:<#(/B-G.+@F=;#@'4
@r2568
CGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCT
+
!/64E?+?>#@**3=8GA<&;28>51H@C:,E%$'F<>?<3E?1C<E5,,5=0F31B-G=:.8G&5<&%7F04,CC##-A"E'A)?7:1(&<&',!=F!CF8=;HF0G@BH7"D,6'4H@-8&5-<7E',3?/EB+>1#,G1
@r2569
GGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTNCCGACGGGCTACGCGCATTCCTGNGCTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGCACAGACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCAAGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGTATGCCCAGCGGAACCGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCANCAAAATTCGGTTTTCTGNCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTT
+
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
@r2570
AACGCCACTGAGGTAAGCCGCATTGCACTTTCGTCCCTGGCAGNGGTCGTCTCTTTCATATACCCNGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTNCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCNCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATAAACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTA
+
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
@r2571
CCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAANGAAACGC
+
)0*+;=H>"<29.<+<HG,DD)>GH(<)0'7E?3C(1)H:@F>)H'8-52;*34*D%&D&("5.G.E1,F0D+!,E&?FC"1/H*3>F3&3G3G,F6,
@r2572
CGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTCTCTATGACAAGGATGAAG
+
<),:99".&E?6-?"?3E:60D7*D?H%5?D2'F*;4D5<"B5DE,.>92!EB4:>;78*8,A#6"*9<81"-/4G(E5.D(B,(3-5/<7E>9F:F1/BA&:@4
@r2573
ATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAATAAATTACCTTCATATTTAACTGGATCATCTATTATTAAATCAGAAAGACGANGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAAT
+
:+C-A!)2&@>B!0;G56=&#0G.0@+@*4"D+=20A+4F;+-<<?F0#%9*(=#896$C*@$F&8C!::#8F+8,9G(FF0$;FE9H<7B($9;!;)?@)'($1CF2A$**5CFAE2FH7';1=.3H>C8+-E.!2=&?F)<C#&#;&1->8<'%A#$#8"+BB&$1/+FG+B9DCC=E5/1<$$0<%6&277.?90;7G/0*+B!3=ADD,5&&;/7@1"')2,0*/5@15F1$,A=6-3B)8G=)*E@+.:8<A-%=*90,"%0)*(%4C=@0H)BC5H22>@6B&:6&6A0(("AA)4-E.&F16
@r2574
ATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCNCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAGGAATGAACATC
+
6&=B6,>$.2%&C4(E9=*G&-BE,*C>1HGG.9E2'$7&=+:!-!)-C4G@19<B?DF=/?!::<#G#63?17"+*9::,47'C7GH<"!HE2$'3@"?!-8";G(.;:!00)&3&04C'*A6A"@0<2-6=?93A;%.-<=E:@*;+?8$<B%::?*AD%&)5$9HC("$2>-A2"?/@@&>4A@G1(>;#&%:+%GD+3)HC<-3G<0BA:H".2GB#,*E'H%:3!@+-$H/1ED'08E?A3D:-)70&E$44:/D'8$*D
@r2575
NAGAAAATCGGTAGCAACTGGAAATCATTCAACACCCGNACTATCGGAAGTTCACCAGCCAGCCGCAGCNNGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATT
+
#&')+#$&"&"%&($)%'"#%&)+*!*#(#('')"&$!()"%+$&%'"&"+##&')("*%#(+&'&&!!%(#*)&(*''"&*"!(++&$($%'#$+#)"!%)**%'(+&!*%*&!+!#!+$)+(!!*"%)##(**"$($!$&*'**&%$'%(*&*")"#'#'(!)(+%!&#*'+(*#$#('+#!((&&$*((#&#%$%$'!*"%*!
@r2576
AGACGCCGGGCTATTTTCAGATAACCGCNACGCCGCATCTTGCCGTTTTTGACCCGACGGTACAGNTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAANCCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCAGGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGA
+
#?:;/$A1G2F;(3A:D"($E640.E4"0%B@,;:--)/,:%?F<1;44($*F,9<8);$<:,/"C6,&E/3H,AE5++E/E'*=)5?0A>0=#@,<A>3<'5"0#05<<@'?*-!;.''#A2':58():"/-2$#@/2*GE;>)A'B769BA.?>=%2F"-33!=)2CD?)7/2;;E.EH'<G22>.23DB+@B'A?B-*A7!9#!424C@#,#D7B*CFA*8:%6594/1#"5-BB%)DB=;&"@%/;'9<6D4D764(2CD6&)&%$H
@r2577
TCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGNGCCGGGTGAGGAAAGCTGNCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGNGTNTGGATGAGGCCATCAATAAAACNTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCCGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAANCGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGANAGAGCAGATTTATAACCGCTTCACACTGNCGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTNGATCTGACCGANGCGCAG
+
01A'-!BH@21?C6;&<+&=B?A>5")3A-)A/)3CG2E'4=#<H6F94=+>5:H-9&G:A;<#7!#==!>-BB84(<'5>$";2H,A=$101,C>F4C.808$4A:>:"G96$0&"=GG!6B5E74HFB?!::>819DA$:8:'?F-:<B)0)>?'6CE)&('H=$#(FAF>124F49$96&F+B49E-7%6?E*D,29696,/C&8&=B@5C#B"A:BB1'*H>.=7D8&741"'9?6E.$57GA5)>=?0:)87%@.!$%/&!8HC!HE/DE='-(@$G<%*8+7$/*B83&?!2%6;9H-96:@2/8D3A&2AC,H-<"=90;A%:/$-3/6!8(5("B/=>;.#'A@6.$1=1F%53D@!6G$-!?>8?&F<22':<AG/!";%?+=7A,>6F8<"67D/FH&.<=8'6(+E#C)>2F5E*F5'$;/A34:D(,CG"93>6B('F6<1%?>.*9&@?<*?.D76
@r2578
TATCTGAAAGTACTGATGAGCGGTGCGGTGATTTATGATGGCGCGGCGAACGCGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTT
+
7H&%DG8$+0-6&7B/&>@;%@,17'6*F2>@9-F-8$07<D=H!H8B7,B38&7">G%EG-$3:+95EB6$=>%"(8>!28!?0'H1'(*3;//H&'EE6&1%4F.3!&/,E-976>02D+2:<8>FB39%;/3?>D0%=.-:G:4BD>,'+2H")+":;9--19>C
@r2579
GTCGTCATACACTGAAATCATCGATGNGAAACAGTGCTACCCGAACTCGGCA
+
0/>F(1"+*1#*B-3>&7E@H$;/5*<@E@$;B*8(6G5?0&:#FDH'0&#&
@r2580
NGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGANATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGG
+
$+**#$$!'*'!$"(***&'#(+"!"'+'&!"*'"!'(#(*++#'"!(#+)*&%*!#%%$+*('("'&'&''(#+!)"!)&*%$"+&*#+#*"(&!+$$#!&('"(!'#'!($'%"(*("'"!#$'+#)(*$+'&*"$%"(''*'$
@r2581
NCNAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGT
+
)&!42AB<#(,:?"0;,AA8=>%H46:!("H1CC!=@9'53-
@r2582
TTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTANCACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATNATGGTTGCATGTACTAAGGAGGTTGNATGGAACAACGCATAACCCTGAANGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCNCTTCCCGAGTAACAATAAAACAACAGCATAAATAACCNCGCTCTTACACATTCNAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCACAATTCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCA
+
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
@r2583
TTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGA
+
(>G>!G&!8"!-+)C9D#F7'%9G?3@>9!(,13=),(G>(&+278))2/-+0$:FA>@%;C,,B1@7=!5'97(4C8D0F%0/9F#:A=,E/<=)A?%)@-E#'H#++"+ADC1$9E/HB"$?%;2B"1=F%B1E<$=G@-%76G931",)7>:!!2AF33#D(DF3"**D=.7(+B8&1?@>'%
@r2584
TCAGAAACCATATAGTAAATTAGNTNCACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGNTAANACGTTGCTCATAGCAGATATGGTAGAGCCGCAGACACGTNGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGNGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTANATATTTTTTGCATGAGAGAATTTGTNCCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTT
+
+F)A'7"/A;8#4D/F02!?7*13A265%!<7!G1;)*+2@5'43DG,755?G;G>4F';=0$(4.%'7>F102>86<+/:AB/F$$'0*$A&,5E:65+/.G&?EA'=";5*B--97*6*F-4B@9A'G>4?GB4B,"+1A&)2G$,+4C?C<,@-2A):-$9G&$&*GE;<)9'89BA39>4$&5E@71AC4.@1#"%"/$*/'3BF*-H@1#>#H.:/G*-';;$:3>D*#!C3?;D)3*F537,//#3/F:.C"<D*4'F":-H/<A'?..#9$4G,0(GH81FE01+822E<C4;0:D0!@0C<!?7>C+:-)"2<9E/?-37.0
@r2585
ATTTGNCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGC
+
+,HH4A119##A1;4@$/5+2!6"!2,<H.=%H1>2'4:G;!(
@r2586
TCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTAGTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATANACAATAACTACCGATGTCATATACCCATACTCTCTAGTCTTGGCCAGTCGGCGCGTTCCGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATAGGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGNAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATT
+
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
@r2587
CCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGNGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGAT
+
&/6/746(;F6%*36)H00'1>A:=?2C*@4<7;128,+<..&H8'GEH0'>%*6C(6$:!%;?:%B4(<?$:G:$>.5F9,-"6/C#7)H.*@!$6'>0@9,E06$0H8G>=?.GF6-+*D9/C#16%#@.)&.(91=6A8E4/%E8">7>@$E0G$C6:$F2A+G.C(":0"@7BFD!2F8>.;/
@r2588
TGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGAACAAATCGTTGTAAATCCCCG
+
A1%><B2C'-#"4B4?=,:*;"$1@6&=%?%?A45:G!+C4FA.825E')D4?5A-F=<!C8
@r2589
AACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGT
+
CE'E5$A<C;'9&G%2)1H+'(6:#EE<4B74E2=>'(*A:C(4,"1$889C4H*,)(//A+)A%(<0%H6##E:G7+#1,%!"D(#749A=CE99*F/%0$+%9$/H6,'HF<:'1/-6&223#6':9&-"30DC8!?C)'-'2C4A.&27)&("=A%.@&'AC!#+)/9/1831596-:5?0+;.61$A#'#BE.@<.;>/.F@A)=G=31@(2"1A.9+4-'74('&3/DG;HBE2"A8*38+;F,:=E,+:&1G'"@.:438$79+A#E#0#4?%*G2?GG:&;2.$E
@r2590
ACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGANGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCCCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATT
+
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
@r2591
CCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTNTATTTGGTCCAAACATGCCGCNTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACNCATAGGTTTTACGCAGAATNGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGNCTGGCGTAACCATCAT
+
#683<:37<4'-A$3*!/&4CB+B(*29D35-2!H"7>?G"D?,<96D3'<;2*20D./9-+9!A?7-'AH=8G6#4-H;H'6)?%#<@:G?)@3;.=4;$F8!FH)8.48;3&%98:C7G.&5C*53G>B4*.A,%+F=08CF-=*%1,/%:029)''&;6=<H*'?#:=CC;>(9)B1;A%!D*0$HEE.*6='BF#H$:@;#AGG##.**-+15-ED&.4:B"!H?#D%?4+4@+74F95#'%CABB5,C2//$6>59&$.'9@%:<G=?,.D=A/G8-&B=)("%&E'6)C@,1'E4F,,1&3"4
@r2592
TGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTACTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGGGAGTTTNATGACTAAAAAACCATGGGAAAGAANACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAAC
+
?->DG6C!2&"D*6?&?2-2,,<"C0=EF,;@5$%1'8%).1-6,#4$+BHE%2.'.(CH@B16:687+A0>"G-;(;D9:,'/:(*@7?7-0*A&.-E8@'(6!A),AA$<-.F!?)B/,','+2C;+?'8)30@.?63/<7/=9&<>D3"//AE9*?('?43<5->7!"?-%)<23%:62-"G9=D"292HDA$E6%>02:>4D(16%=E*<;($C<5@3CD'H>AA.37),8E/FA79;D%(DG-$BH/1+4>G:+;2=<=0C=@3F2B%E#/!E):')-)!@D$31=
@r2593
TCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTT
+
A1A'0;$9$9?4+C?=680';#-A9D;)<3)H#+,<34#:!%@9*:!C=&6($+2:?8:)<CH'-;%?8G3D@;@%>*F;/D-F,G.+>!:)
@r2594
GNNAACGCGGCATAACATGCAGTGGACGCCAGAANATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGANATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAACTATCCTCAATAGGGAATAATATATGNTTTCCATTCCNTCGGGAAAAAGTTTTGTTCAACACACCNAGCTCAATCAACTCANTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAANCATAGATTGNTCTTCTGTAAGGTTTTGAATTACTGATCGCACTNTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACATCAGTTATACATTCTGCCATAGATTATANCTANGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATT
+
&(!+!"&#!$'*%$*("*"%#(*!')##%'#!)')#%%)(+)*#'(#$$(!!!$*)*+$$*+'!)'&!(!%#%!"+$$!(*($%("")($#''*'((#!*&&(&*'!*"&+%#&*)))(!*#+%!+'%'+'!*&&)"&'*(*!(!+%#*$'%#&!%)'&!*&$%+&#'"*(#(%("%'(*&!("+%%!%!)*'$)%(*%"(*"*!($&*)(%#(%)+)(##*#&!'*+%()#%%#+(")))*'%*$$(#"%$#"!!&'""+*(""*&()"+$"#)!$*$$*%$$$+)*!+%+**&%%+&##*+*#&+%$!+%'+'))+*'(+$$&#%!+#*'+&*'#!($%!"$))**!''$#'#$&$()(+('##!%*$")%)*)&("%"&(!($"!&%#)+%$)(*)%#"!!+#)&)!&)+&(*#!+$''')(+++*)(*!+&&!%+%*'!*#$*))#)!'"$#*!&!(*%!!*$%$+"'&%+("#%#+(!)#)*%###)""!%+()#$+&')+#$(()$&)("&()*)$&')#*!)!+!&##$*+!+'$"('$%&#&(*!+"(*&(((##$&*'$$)$"+(%'(&+*#(%"""
@r2595
TTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGTCTTCTTTTCTTTCACGACTNCCCCACACCCAGCATGCANACCTTTCCGCCATAACTGTCGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTT
+
+%#2G@"#2;9=$;3@<0!E;%4":E5#9=-&53-*>()38#<DA"@>4B4F&+9,BD8D.#%".(,<B</5A-?H2->E1,B2/5#./4>G71!'99.*/@>>57>9?*F?D/52((A3HEH6BH/#3$H081/>)$:3<->3=<0;%'?1G:%?*0D@,:;=HA-"C.G0*/!&(G#%%4&'+$-.7#A/*E;G!*9&'B&C5-B9(;3%2/#D>?82GB#:G.3.$
@r2596
AGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTG
+
9,1.+&:)&C1G.8H%8,B9.5G412(?BG+>99$)-4#$A!%8G:)#.5"(FH:,9>?-
@r2597
ATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACGTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGNCATAATGACTCCTGTTGATAGATCCAGTAATGACCTC
+
G+C$+<7'"&:922#:!$)<A@#$$<.B5AF60F60.4>D+DC!*B1;6&DG#(3@9?=(5.($D(1;45>/-&*D-E1@=#-'9/B3<%?/(*F47)#.D%/D),+)$"7)-1(B6=%03G/331<8:'/*=@H.BH6(A<B+,:B)@D?/8E8./+&4GA.4?/53/>4G)8A625A#76*B4&:7"D$:"AGD1-F"?G>@FB&)D;-2((*-#D(FH1!-;3#<D1%15!-G$>::#>-%?@6">@$H=.08'3'$E-#@5?).17<HD7>>&74&F(67(B<?@>6%9=0"B'$8FE*2*'%"84G$F::$G/*1'4*(A-1)&+&%!).)<<-1$C&2&'6B&&=5=2'!<*(.;1$5@=#&5"D=+@<G;=>(<>19"E&,632.B:6@,6E)HA,59;A'46!:"A)F61&;/
@r2598
NNGCCTGGCCANAANGCAANANCGGGANGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATCGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTTATGAACCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCNTTGTAGGCTCCNGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGNCGTGGAGACAC
+
"'*$%"((*%"!*#!'%&)'")!&+#+$*")&$$!)!(&#"$''+&''&"$#)&"+"%'%(&)+"+#(!&##%&"+'!&))&)%&#*'**&)!'%("'&+**%&%&+($*%)$*%%)'*$$!$"+$+)#+!$(#"%*"!)++$*#%&!"&('*!$+())&''"&(+#)!#"+*%*%'"$!#+*%'+(++$*##&%)")#&*+!#(+)$++)%"#!%(('*#+!"$'"&*$#'*%%*!+)'*($(!!+$++%#!*"%$%()#(+(&*#*+%$
@r2599
CTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAA
+
.:C$6A$23))G%1:!"!90G5B('(+$.4;6?C8:>0F9-#?=(HG;6$%>D';5?>%;53*9(.8;&>$()<0/21'=4'9H6A0,H$D-+G%C!HB);;H7&#A'<8>;6<.#&<&35!20GE&?B:/90GH27"6=FF-2#8D9'"(>!C!F@D</A</$&0D3%9
@r2600
CCTGACAAAGGATAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCNCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGAGCATTTTCTTCCTATTGCACATTATCNTGAATTTTCGGTGATGCCTATTAATTTAGTTNCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGAAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGNGANCAATGGGTATATNCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGNCAAACACAGAGCTCTTCATCATTTCAAGCTANTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTG
+
?3!$618'2/&"49C::67+>#<1@-E44).-/09"4)-G1+.--6@6%:>G"%:D6@#/(64:>E-A,:@.E2?D-6DF88/4>-!&#+&$/@%A-6),"B#.=;/'FH#+D!#0$C;=9DG4(0DF9<02,&379D%>H:7;"%D>*7<4BA='@;D0537"02*/.=-;H"?70D&2,>0?BF50':#5<577#F$8@4@.;<D5CG=FHH1(1-&B51>1+G7?;:CC3)E%6F%&B3EA-=/*/C@,%E!/<1C7;0095";-A69(/9FF974C;5$H0.(8CH<;)>H'>2-F*)%H!!;=?!B4(B##7BB1.76)6(:E/($H%;+;G"D4B+='G+-86#(AD=,10*49<G?0:83F@@+)D:.(D.,;,B$6&,$*?F%225H0&+9;0B63#3BD2D:*5=(+53!B*)'3*C6?<!0#@)02GE8=/+?BF6><-0+-;;=@6@50;/)2H6:2*BC:7..
@r2601
GATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCNATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGNATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGNAATCCGACAATTCTGGCAAACCATTTAACACACGTGCNAACTGTCCATGAATT
+
$$E=8$01%$',$2!0@,H;:!#+%+E@7B'-5=E5*2HB=G42/.@*A5@348A6$+-)?/-?!%-E;>4;.G&231#=*'49#2E!0C.,!H?D5(?4&?FA<?(%4$97@9?7C'(%%CDH3!;A31A/?>G*G5))H?:=2.6<@20');E76B?!=E:28:7B".#&*:#8-+8'B1%.=/'=+$2"A60'BDA**AA/8'%%H5*=1E
@r2602
CCACNGATTTTTATCAATAGTCGTAGTCATACGGATAGNCCTGGTATTGTTCCATCACANCCTGAGGATGCTCTTCGAACTCTTCAAATTNTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTNAACCACATCAGGCTCGGTGGTTCTCNTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGNACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTG
+
(*(#-#1'AB-1*/#&*=F:E#9B5"A<<F;8,,157"@/1'%E.:$',+=8-$C%0"(0)<H-HD#E4.73?@.,(FBCCB:5%=@A<<G#%8D#'DB*5/(2!@%=D)$63$,%;8F-D?)A+#-7;5F>80B9?+)?A0:.=!>84(C(&)"1<+;B-+6.1H&G;8H!277.%92+&%4;)$.-)BFA5.>DH7GEH@@!;#2E$A*FG,=5!!F)C9<"G+'48&,#&:)&83A<F39B'&.,"<"="7"/D&A3*.&8*%B6H)!5%/4,B?0+/B.05>,#4H?:08204:8''+H'.>>&5!8:5.!&%0"8BEH&,2-F@5@A6//%"36:1915C99A0
@r2603
CACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACANGGTNGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATTCCATAAGTCAGATCGGCTGAACTCCAC
+
#'%(+'"'&('$")'"&"!"#&"*+""#*&#&*$*&'!#&""%%!*&%%'((&$&&"!)()+++*"$)*%*+#'+$"!%%+('&('!)!'&)&)('#++"%+(*)'"#++%!)*+#&&""*$&(!"###!%"$!'(!+!!)%'#*"#$!$(+"$*)'&!(&"'!&)')!+*%!)"%%(&
@r2604
ACCACAGATTCAAGTGGACGATGATAAATTCACTANATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAA
+
*+**!!"*"#$$()$")%#)+)"+#!)*'!()$&*'%#'"()%$&&*)+'''""+"**)*+*!'%"$**&'$*$"&("%++(((+"$!)(*$+!&('*(&)&+#)"+&*#*$'())&''"!+*&'+!&+($"%))+$#%+'%*+#(&*'&%&%*+""%)+)'""*"%##!+&+&#&'+'")%%!!!#+)$'&%%"($(%"*(&"!*!+*$'%&)"*#'#$&*$%"+'%!)#+(&
@r2605
AGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTNGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGNATTACACAGAATATGGCGGCGATGCTGACCGGCAGTNAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGNGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGG
+
0"*<3+,&+<=$2&5D"&ED9$;G-++7C52F?H?1<DD+0.=F77C>./>"A*>=&E4:2F,8511%+/7%FD.5B8(+&5H(G)@C$?@;A<5<#B4$@E))182889:,-G9D))0)72D-4*&8&)3146-'&4/"?9G7.?+G>7*5A%:%#&1E.-BG)7$G''E?/(.,"C6>.H.8-C.A?(8(D5;;+F<"0H?"2?HH$6:@*-#*G@?#9B".!2=D?'+(6&B&*3!AD'7!73>3=/:!H0<>2E11AG)%,/.7;=-3'<0
@r2606
GCTCACTTCGAACCTCTCTGTTTACTGATAAGTNCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGGATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCNGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAATCACTGGCAGATTACGCCCGTGCCTTATCCGGANAGGANGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAGGACGGA
+
;2(BHF&FGD580-?),F/52;1"7-G)%4;C"C'43,=>C=.5F<4#84E;99*.C*=(/=F&:!813%!#-C66#49<%47(>B<.)!4D?E&%16*34G2/):>2&B)0HG=$04C0.&,")&BA)8H0)BH=E8G!<!B3.!:$:B=/%H$;;56(!#>@(/0B'0H?008?9'CE$2.<#959G4F:>FC+!7./=5H;1,$CB>3-"98H6D'D(.$=9!G'A?BEDH("4E/!0.=#CG'B(<A!+C>6+#HE/(G71&,94.4;)57-0''F&3+(@283+,B>/?:#9,*;33H>/,=%?B'62F&+-1E.5%/E42;1?-B,-#+9;*1/*76+'(&;?8G$E.8:1D%*70)D$B:B*#9@+*;(C85**+><"8;(=9:1(6A;960/B@)/:)G
@r2607
NTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCAGCTGGCCAGGNTTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGGTTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCATGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTNCCCATTTCTGATCCTCTTCAAAAGGCCA
+
$"+&!&$'()"&+!*(*)!!!'#%((&!''")"!+'!*$*!#"(")+&"%*($(#$"')*)%)"##$%'$#+!$%!)#'*#)'"*&%*#$'(&""%$%)&)!#(&&+'&+($#)%!!"**%(#(&%#(*)"%"+**((('!&*($+)*!#'%%%"$)"'!'!("++%'!'#")+&!(%#()#!!"+&#*('$*+&!''**!*$(%$%&+!(%&'"""*+))$!+(*)''***)*%$%))$&')*!'$"&(%"$$%)'%+$*!$"#%'"""%&#'(+"&$&(+("&%#!%"*"!+'*&#(*)'(%+*&&*$)"%+(**'$*"%%&%(+&"%&#)('$*++)
@r2608
TTAGNAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTAATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGNTCTCCACCGACCTCTGTNAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATNTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCNCGGCAGGCGCTCGCTGAGAATAGCCATCACCAANGCGCACCTTTCTTANAGAAGGGACCGAAGCCACATTCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCNCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCNCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTG
+
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
@r2609
GCGNGTCNANTCAGCNACCTCAAACCGGCCNGTGGCATGTCATGCAGCGTGTNGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCNCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGNGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAACAAAGCGATGAAACATACTGNACTCCGTGCAGCCGT
+
)'!#%*(%*#$('))%*(!""&)("!$')%$(%+"('''&+!"%&+*)#))'+!!)$%'+$))(#+'!&&"&'$!#'"(*#'&+&+%+(!))&((+''$(!'"%$*)#&+)''"*$*$%$*+&&)($%$')(!($*#()())#%(!+)%++$$*'$'*))!!!%*"$()"'+'#%$+')(+*&#'#!**&!)!$%'#$#'+%#+!%#$$"!''*)'#"*'$(&'$(*"%&'%*#$$$$!)
@r2610
TAANTNAATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACNCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCGATGTTNTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGT
+
&*(#)##+"")*$"*!$&$#'+(&)%*)+#%&+!%('+(*%&$+!+'#*(*!&+#(!**))+(&((()$!)+!!$%#"'+&%+$&)&"'&'+)'($"#"&)"$#'$+"'&$&!$*)+"+&"$!%+*+()(#'#'))!$+*+'()+)(#*""++#$%"'(#"+!
@r2611
CGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTNTCCTCTGTCATTACGTCATGGTCGATTTCNATTTCTANTGATGCTTTCCAGTCGTAATCAATGATGTATT
+
E)D,;H6$D"F"'E2?A7>@9B&1#2<7(8$E8#(!G:-+F%?A&;$+:@A+/'#!%G#?9DA1B8<#AA)643;H19?=>#(%;253%28DA.(.<&'$"@5068%A/:10.@AEA98C13$=;E-#;
@r2612
ACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGNGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATTGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATANCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAAC
+
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
@r2613
NAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTG
+
-@);(3=632B98G<-<>#'(6A-=>H*+.0#$8**:"*4"'@G'7?!#30:3-%:/1##))/0==9%D(52/=1&.'74,F&@+$*C>*?G0,34G2:)H2=8.>/D+=698%/,F8E@-%(:="*C=()8!##'%A/0>)*21<3F/&;5?:>0GE(2$(06?7$GF%AA>2-2+)%/(ED&1;G618G)8DC*"<.>3".;@FD85
@r2614
TTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCANAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGAGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACANTACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGNATACGCNACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGNTCGGCGCACCTGCCGGAAAGGCCGAATNCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGNGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTNTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCTTTCC
+
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
@r2615
GGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGACAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGGAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGNGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACT
+
H+"?F?0<$GA6)A>,H397H2?$6B2)5DH+@-75,.ACD>;:?)+;@)9E1@!A,>22F5C;+,#:-!-9&79/$(3:.%*1?5'HEBFF0!%H9F:*3F!*"-"H89C,'2GA,+-=6?,(=<'D-A4'@E""7"3=:HD@;F8@=B?=<3A92$<D+9GH,;E>77?;!AGB;00$13%D29)5<A:1:5=D#%/:>F=1%08)9952:50>1</-"H.8E78%@D>%H)18G:9-:4/2/A235E,
@r2616
GGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGNACATGCCGGATTTACNGCAAGGACCNTAATCATCCGATCTGCGTTACCGAAT
+
H"B>'8092"<+'8'(<:8B<E+E(879G%!:B3:2#ADC"?;54@1E-D#,-.!3>F=!)#)%"#9HF)$24>9#8:"H.?!*+,7)7*E7C#A-#"<.9"H5++!"@;>&41=0:D=37C*G.,!%-G83B-4>->&+4&(+$)D!09"*/*72@CDF+7+8(4=0E:F5?A;"'-(8<!-74:(=)<98!7+E7+%BDB231(9+E+)%D79@?9<)6BG0:&BE!B-HB;6'9+A<9G.''>>54+,C&(B?E.%(F97;@'5-+B=BF2C?>,+6D%'G7-E0D.$7G
@r2617
ATTCNGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGCCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCGGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGGGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACA
+
A5#B(5G;(!?C*96%A#*<46324'+A,$-9-283H8A?FBC+602HD%4G+;%E$F,)*)-F&4B9!;<-:;('>?B?'2.&@&2+HB&/G</-7#$*5E9#=%94<-D'DE@3:6B72"/F>H:;:+$2E&/'"D@#3?#/!%HE4>*BB1'.C&?*9'"!'<204($!6B'3!B%H$855:04C()<@2):4D<$&655*'%$DC*;4%;,!DGE'<8B
@r2618
TCGNTNNGNNAATANGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGA
+
*')$*"!$!"*%%$%+$(!&*'%))**#$"!##&&&)*+''&*!%('!'!%&#*+%+#&"'&!##('%(*'&')*)*&$$"(&()%!")(#()++(##+#+'$()"#"(#%#"*'*)&#*&##(%)#*)##*#$
@r2619
AAGGCCTGCGATTACCAGCANGCCTGTTATTAGCTCAGTA
+
H;5BC?G2%4EC!8E>?-2+3#1@A;A381<"*@01,9,1
@r2620
CGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATC
+
8$HHA$-?+B41H?$F8>4D!&DGG;6FA&#E"2A4>D$*."+<&F4=D,
@r2621
GGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCANAATCTTTCAGGGTTATGCG
+
>5A;)6B316&=G+0#H5=&@7@?-7E0F54#>@=A+=H+,G81,"4D>G1*EH-(*!A2B%C*80E-C;>''/79*>9-E/#1EC)1?@>%+B/0%;'9!BB)68,0,GAFE?!>:"E?2B//:C9*C0GE<;AD=?GD=D"C"*=04+6;F!.,HA:"G2.*G@"=A*%0/)"#!>#"F>7>298==*3)69/<;;%
@r2622
AGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCNGGAGCAGACTCCGNCGGAGGGATTTGAATCCTCCGNCTC
+
;<3D#480&>&B9%%'8!C'))??C'<:?2#"7*=,9*"68D00.%8BF.@3+'/1/3G&E429)3.BA';D&(-?'DD/2<G>A6D+6#5E.((C$&A2@/D(9.AF))73E>:6,945+'-"2"+@$;5)!>*&:HD/?827B#*("4:4>2$15)07>::+)2&7>!?'&(';B*,+:>G>-.;?7+"2//6)7B9@5@,D3;28&9>H1(;>#0@91%:2:&D:0%G<*@<C6'<!?<6%"GA0:'8?(1)AGA),!).?6E/H65.>81B20C$G8$+9>/$-"D*-4-%%%$%<!63B-B'C/G.G&#3(AF(*1D@""G51$E.E7.3E%?2&$.?29"!B%*,*.4+E85?4&,C#E!90*B@#!*B'
@r2623
CCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGNGCATGGCCACACCTNCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCNTGCCGNTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGAGGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTNTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGNTCTGCACTTCCAGCTCTGCAATATATTTTTTCNGGTCAGACACGGAAGTGGCCGTAAAGTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGT
+
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
@r2624
TTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTTTGGTTCAGCTTTTTTATACTAAGNTGGCATTATAAAAAAGCATTGCTTATCAGTTTGT
+
1@A*2G0GED45@!.'>(>GG7>9=!&&-+:15B(+$%9)+8=C=)%45(@.4.*'FD(3G!9012!%(!-*8*268@9(G0&2E<0$)(1-6=%#)/$0(67+(
@r2625
ACNCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGC
+
>%6.C#2!8*A&/,?,4>=#5!38($!#76'3+2*4::'7+%*'?=&G).F++;-@5,/":7?5A%DC&D,('%&GF!4;
@r2626
AGATGATAAATGCACTTCCGAGTCGCAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGNGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTA
+
3D)5@9681%.$?F1%'D$!=2+B=%.498:$E2A::8;6=1"2F/$07"88&(:,B7%>?'CD**A%+%@./H$GF9-*"C&5*68+2<8./D5@@;%%;:A+H6=$>09191C4G,:@4AD>C%G4"F(D
@r2627
TTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGNAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCANGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACGCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATCAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGNTGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTCGGCAGGTAATAGTTAGAGCCTGCATAACTGTTTCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGNAACAGCACAACCCAAACTGNGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAANGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTANATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGNCCTGTTGGCCGCCATTCTCGCGGCAAANGAACAANGCATCGGGGCAATCCTTGCGTTTGCAATGNCGTACCTTCGCGGCAGATATAATGGCGGTGCGT
+
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
@r2628
GACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATA
+
</A1<;+',)C75$@(9F->!;$)'19?2;E.F4<+):'D@>G0!=A/*80G=3A%H#H&H1=?+%F0$<"17G2,'"E@+,#2?D(G(6(
@r2629
GCTGNCAGCTGGNNCNANGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTNCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCNTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGNGCAGACCGGCATGA
+
$'#$#&)*(&'%%!)"""&)+)%$)%(+!"**&!%!')%+*$%%%(!%""&%')'')*"#)%#!%""%!(*"+((&'+()&"'+'&!&#(!+")$+*$)($$*#++*!'(+%+##(+!)&)%*)$#!'"+'&(&'%!$&!%"'%'"%"$+(*%'*#)$+$#%(#*$!%+"+))$"*%"%%)("#%#%'"(!+'$*$*&&&'(&)('(!%"!+)($""$#&++!'*++"+''%$$!*$'%%%%)&$+'*((%)%&)))&!)$"*'!$!(++"%%!&%#+%#$
@r2630
TTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGT
+
$B3%.%4+<+%+/#1#48""):1<0HH&E,;!H!&"8H2G4&*36-$=GE3.5*<4!D!H4><?$=BE9,-0/<-?-200B:.(E4C+5??CF4/&/B<
@r2631
TTAACGCTAAAGCACTGGCCTGGGGAAAACGGTACGAGAACGACGCCAGAAGCCTGTTTGAATNCACTTCCGGCGTNA
+
+&"')&#++&#!!+&&"&&+%)$#&*!$*"(&&*#)%('&*)"&'*+'((%+!#""!$$')+!%#%%(+$++(#!"%+
@r2632
AGGANACATTGTCCTGATNAANNTGNATNCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAA
+
(#"'!%("&("(*&**!)'$)#&%!!'$!++#*(%$&(&"*%'!+$%#%+)"('$*"!)(##!%*%!(#(+%!+*%+)%#%$#%!*(""'$*'*%$(#("&*'**#"$()'(($%*$$'*%"
@r2633
GNAGCANTACCGAATCCGGCTTGTGATTGCGCCATCCCCATTGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATG
+
*#$&#&!&+!"&)$"#%#*!'+(%!#"$%)$%$++!##"!%+$$"$&$))%"!"%))(!'%+!%!#+$+%)$)#")%+"'&!&$&$&'#$'$("'''"($'"#%$!+*&''+&%+!!#*('%''$
@r2634
TTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGATGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCCATTATTGGAAAAGAGTTATGTATCAGTGNCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATANGATGAAAGATAGAAAATTACGACGCTTATCGGAAGNGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTANNAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACNGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATG
+
)*%:>-$"',5/>6,8@:C%'6%8/CD-)+7;+%13A9.>+9#50814/25H-10::E84+E4E-/8;5(%.>:)>$4G(&=E"8:;4H<AA+1<E.$/:G>":'C#6F:(?AA'2(;<E+'-2/*&/D?7@%7=3#;A=)%E/D/7"ED:@=25=$5.@@3FEG/=5,C;B?$"E?<',8*46BH-F==9?83"6F@H@;E)B(@9-,C.HG=439H>FA)-.4C04EDH?<*G+0B5A8G4(<#"'.CD@2/D5#?B>5+#*G+2.D$<!/-,52.:?!?@<-3??40G))(/H+7+>4E)F;<,%0>*/&1285%)?7A?D-.4$52@,E@;;B3"<E2;!'F8&78C')49!&:)#9EB+47.#$!0-(26+.B!3:</1@8"5B3"49)!>HG!(.=@(35G(&%3&+/:?G!$45+%:./C056,=4/%1$,$9*5F!1!)-');!!17="1D20.8HG.
@r2635
NNATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAG
+
&&&;.H4A=-92$@A:?5"!75>#41D76#0AD>5%@;:HA,>1D(>&-9'<AHA!01$=6/&FG-
@r2636
GTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGAGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGC
+
8GC13"1.%;!1$@G>DF0:;E.&56(>$>*'GH8#-FD--66&",4,-/GD?7<4>5)!9!&3%<H,)5G7@B#E?)#<&079.!'<-?:.9!G(*.%;H=:(H+:>8)E?7571>7C772*&&9.G55>5*B<""@--8=25>31:=)A/83$.&HH/C<=3&+7*-*A0%&>)">/ECB).(+%A"*3C&+@A</#(>
@r2637
ATGCTTGNANNNCTGATTGNTGNCTTGNCGTTTCTAATCGGAAGCAGAACGCGCCGACTGNCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAACTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGNCTACATGATNCCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCCCGATCGCCCCCAAAACACATAACCAATTGTATTTATTGNAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAAC
+
$*%!)')"'&)&))%()*)%)$+(&%"#$$"$*#'(+)%&(#'!&"&$#!$''+%%#$"%#*))$!*%$"!#("$*+%%(''%+(%#+%!%%!(&#!(&%!'$+'!+$*&'#*'(%#$*('#)(&#($#*'))($)(&)%""&"+!''"&"'$+#)'+%##)"#((&%'#$#*(()$%$!("')#%#)&*#*)#()"(!(*&$!"*&+((&)%!!)+#)'#*('+*+"$')+&*$(#&"*('%%!)"!'**+#!*(!"!$%"&#"$&('&*&%)&")$%%+*$#"$!(%+%$"'$()+""%'(+$'#$(!!%+#!%"&&+(*%%&*!#+&*"*(&!&+$%$%!#%#!('+*("("($"%(')+$!$!!$!*%($%%!#$(*!$!%($)&+%(($$+%"%)*#'&(((
@r2638
GCTGACCACAGACCCGACGTCNGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAANGCCATGTGGGATGCGGTGCTGGATATTGGT
+
(3(!>B?*/$!8!%&9@-A%658D";B35>5'0H6E=17G;++C59G@2;<!+#<"G(51B<>3'*!%G(.=(?8"5@A&*<+))/8>CB1D7FG@,54HF)?/05&/5+>!2,?G%6E%G'E*#7&F,6@?.G.5<&(.FB:"!)G:=@/!C+,?>?%(7C"=/<GB4EC;8A(5E3+"<*A/1!F8?)*8)6$..>'50:@+6'=8#HGB%",0'=93E451&D%9645=0'):,3H('EA4CH+CD57.?241C/H.2G
@r2639
CGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACG
+
.C0>-#2,C:<A37>>?B,E':-B10!9E>+C*,"<?=!"'+%=;,:%*..D!8;?$/G432&//569)&9$AA
@r2640
TGTTTCGTCAAGCCGTCGTCGCTTATAAAAAATGGATATTAATACTGA
+
0!?)#?@53B->';:DF/!'1'##E&(14F;52/EC.823"4-/#3$)
@r2641
ATCNGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCTTTGA
+
-C#:-<('@1'7*H%$$1?8C!%66/('B!@@;#=$/=.D3%'0,.D1@7)96F
@r2642
GCATTCAGAACACTACACAAATCTTTCCACGCNAAATCATAACGTCCGGTTTCTTCNGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTNAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCGACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGANGTTTACTGTTCAAAACAAACCGNCAGCAGTAGCACCAAAGGAAATCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAACTTTGTGGCGGCGCAGAAAATGTTGTTAAAACNGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCG
+
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
@r2643
CTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAA
+
,=$6':%B:#%:D108+A8.6=>0E"'A?::9H/6'D1D=-'>?0E88D@"0)/E6$
@r2644
ATGNNNNGNTNCNNNNNANNTATNCGNNNCNNGTANNTNTGAGANNNNANGANANNCGAATGATTAACNNGCGAGGGANNNNNNCTNTTTCCANTNNTACGNNNNNGGNTNTGGNCACACGACACNCCCGNNTTACANCNGTNCGTGTNNCNTTAGCGNNNANNTNCNNNGTTNCNGNNNNNANNNNNAGANNGNNTNANTCANGGTNNGCNNAANCNTNCNNNTANCATAACNNNNNNTNAATNCNNTANCNTNGAACGANTNNTNNNGNNGNANNNNAGGCNCNNTATNCNANAC
+
!"!"$!!#!"!"#$!"!!$$"$#$!$!!!"!!#$"$#$$"!!#"#!$!!!!$"!!!$!#"""$""$!$!!"$#"#$!$"!$!#"$#!$$$"$#!"!!!$!""#!!!#"!"""!$##""!"$#$"$$#$$$$"$$"#!!!#"#$!$""#""#!$$#"!!#"!$!$!$##$!$##"!$$!#!$#!$!"$"###"$"!!$#$!"##!#$$""$#!!#$""!"#"""!!$!$$"$!##!!!!$$!#"#!#"$"!#$#!!"#"$!""$"$!!!"!!!"!""#!"#"#!!!$$$"##!$"!$!
@r2645
AGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCNATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTCCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGANGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTNAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAA
+
,4+=54:'B4<3*8'+2B.E)!'3=H0D>(,"64!$5*1GCF;,031394&7?7#2@<2#-&D6<317.2077'1;.7='DG;G=:)F-4-E3;?,C=9)@#!H9?8#5#"-@+&5&6)DF:.?6C$%-G8.%592;C8/DA.A4"5"4D;((@H-0%$DB'%-5BF;?H225,&%*$E5*#03;%2+<:6=&"@&.F/&*44&5!E2(A.!-9=26A")>5)@,%@$8?(=$'.H!CE&#,5>/G#:*')?36!CA78H$-=/##3(027915@&4,55@G2!&!!+$0-;)=-,,4G/01-+=+G/'28)!7:*H,"/05,#
@r2646
ACTTGATGATGCGTTCGTTTCTGATTATTTTGCTGCCNCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCNTCTGACGCTTTCGCGGCCGCGG
+
?)(>=-!(66".,.&D,@,!3!A++:5#=03$4&*"=74.9>7026!9(6FF;(9,;03G$+2;5BCB;9DBE9-8#/?BG''3F1E'/8*/6:%@69
@r2647
GAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCCGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATGATGACTCCTGTTGATAGA
+
2;B0<0*G--56/,/',0>>7@H'+#&0*+7(=!>#A9:8%:67:;?H+'CH=#<0+0(,H6+"".==3!%'EG;"G2&1/;;#C=H%%G@G(+H>"#1'97*AG0187(@((D,3"&-%C!<,5*;H=**,E<5"');%44:<$%.#$@F==45@+&="6D1/;9>6%#6+G40)3<'+5&)-AB(9!HA='C?%604"H'-:B:2,%3:>&+F-+3;->:)6)6,$0="F84(@#
@r2648
CGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCGGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTNTCCACCACTTCNGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCG
+
,'8='F$*985#".D("4>'(:**8*185-)$>49>32&H":E+2!6!/84<6&*&D"%8CG/>@)'<0%$'#A.0<&"80(1&GA)7A2AF?*#D6.0)/??FCG.A+F>6$#B5@?G$D7>C*;H46:G#59#'+1AH#B%&
@r2649
GGCNCTCGATGCAAAATACACGAAGGTGTTAGCTGATGCTGAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCNTGAAGCCACCAGCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACCGGCAGACACCNCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATCAGCAGNGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATT
+
"$&!;3240F7E4*-4)>&&3DE:6*H8F.8<(;<'?+BG5D@C()!0+(=,F2)16=F8B!*?',G=7/.8*/A7!>'@6@"16/B!B)28%&>*>BG91").><A:4E=.E=9/=#-%0/"=D,-<3<:%;-#GG=,B58@C!=H<HH9@:$F9'219@$=-:1,="?2H:G2/,,@60D(%1=?5*7BG!?0%>#4&944A5C(0F*50EG:5AF@6$)B$5"E030C#7>!56(!+0'!#<G"G@81$5+EF:/+,5B4*654+8BCEC1/+G4.FC+D-7B:DE.5?+1@/H$97(@!-/!B/F!HF62.56+$=GG+.>"=BEED,5D>7:?"$3$?)9F'G)"1%@7C%+0$C(E$;H;B8B;('33A=2:4,
@r2650
TGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTACAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATNGCATNACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGANAACCAGCAGTTT
+
34F,:H:+H735D+'9/<:592H+G<"E8B**?8.$A5&'1.<3/D=H0&(.45/D:E1";$-&(2!>H(,-"(':/%6&/G'#4A$!4&9F?+D?-D2;G?:)72%@8/;/F+%A8=->A.C+G-'9?C#G6"0*=)5D9D=;+#86<H.@HD$H./.39B;11B=@;.6,C@9CG"048BEC17<,%&8>5('?%H>HG6+%/&?C)<>8/B8'EBH?9=B:%%GB/9<'-H3>6:;'&!+/8?'60DB!8/(4,+G">29=9C>1F+G:/(CCD6*9)FEA?+!;8<G/?4":$87%C=*8"&#-+@G94)*441H%2G>F&A;C>>B8!9F=E";3B?@),-*A?;>H</:*76;>9C,0(7%?D4;?/B4$?**,+:)*B#=<8!":8F+*9#/"9C14%)"4";*E>D?*9@/D%(@;G6;3<"5.9**.5-C/+#+$9!'',';(G&A24GG<+99
@r2651
TTGNTATTGCATAGTGATCAGCCTCTCTNTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATNCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATNATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCANCGAGCGCAGCAACATTACGCTGANGCNTCTGCATGTCAGTAA
+
$('$*)(++("+$(%!+"$'+!$&$%*&!'*%%(#'"(#!)'%)%!)#''%'"$$('%*)#*!%*#"&$'#)#*#'"$%+&+')&*("'%''"+*$*&(#)'+&&(%($#$+#%$+(*%)*$$%%+%'**!'!$!+(+$$&*#&*+$%"$("#+'!))*))(+'!(((+"**(''*()%))*'*&("&)+$#$+'*$!&!)**&%))$(#$'$&"("!+'#"*&)'!$&!*$&"*&$&"''#')(('$'**$!%&"!"*()$%&!"!")
@r2652
CGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGG
+
4%4D8$(3B%/6!EC)4!?5$$8<!E!FD!='/":!#:*2-24&@9<,9C#F/++4*F>H<A7,G,G093E0
@r2653
TGAATCCGGGAGCACTTTTTNTATTTAATGAAAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTACATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATAC
+
=9('=%-H=.,(><+&?A-*/*.+5C*;5%B."*!4</%5+?D3<*,@!>)(<.2)&.F,!B3,(4E0$8H@!9;13H7F/(E=;+87+B?<:/4772%,'D'F0?+$(%;E>>0)%#$=>604G?+/#30<"7,8C>B!H7F2?@2?>H%G5@%D8C9.=3=<EF6?=':#9.F7%G(""*E"7&#;09)B-6(D-45(1&="6-//+9-,34(0=,%*(*?!'-,*G?<4:H/"-!'<8<@,;4'3+C3A:A00E?8.==:#"%C?CAD3?C-$E(:*<#!9(-D&(4:;,C?C<F=7@$0*,H#C1%C1(2.&6H,D?:*.AC@<$",*4!=/;?18$"2D(/04&6D1(,!:,>@6H6#B8$-&0>B;$)F%<0%B!,!7G26%G=F.E3%$!.4D?8?:=<;1?A-B@3%(42091;BB$5/>./(?:=98+&H4;?A(G(12&"E>;%:G0=B=CDF79HD=)$C
@r2654
AGANCCTGATGCAGGTAGCCANTGAGCATATTGCGCCGCTTCAGGATGCTGCNGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCNCCTGATACTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTNTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAANATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTNTTCTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGNCTTTCATCTATAATTGGCATTGTATATCGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCGTTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTG
+
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
@r2655
CCCGAANTCTGTTTTGGCAATATCAACCGCCCGGCCTGTACCATGGCANTCTCTGCATCNTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGNATTTCCCCGNTACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGGTTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATAACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGTGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCNTTAAGNAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCNTTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATNTGATTAATTTCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGG
+
*'!&'$"+)#++()$+)"#%(+#(%'#*''#&&'%)%'%%((*#'(#*)*)+#&)&#(&(!)(")$*"%'"#+#!$#&&!#!*!!()#$'#"#!*&"(#+"$'&*"*&+&'*%)$+#%%'##)&$!!$&%(!%#&''#%#'&+('%%%)*%$&&"*%%'!&)!&%)&""+%'!&&)&&'%(#'#%#+$+%)!+%('&(#*!#""&$'$#"+!*('%$!'#*$(&*"""')')&#*'&"()%('*!(#"*#""""$)"&#%*$)#&+!(!%'#)*'!*""&!$+!%&!")$(!&"*+(#'!#+!&**&("%#)")"*"#))*()'#&$&'$"!!(%#(&'!'"(!!$+)$!'***"#'*%#)&+&"+*#%+"&*'(&)'""#&'$'!%)!$($(!+#%#%&#'"'(("&(+%%"#%%+*#&)$((%%'!##"(&%%$*'$*)'''!*!)*%''"%"%(+)"!"'""(+%'(+%%!''#&)##(*%'*%$"'+!!%)'!!+'"&*&#&+*&"!+#(*"%#*'%!&*&'*#")&%$*&#%()&!*"(+'('&"++$*)$$(""$+*$$*%'%+(+('&*#"*$%"%!%##*+'(*+))#'(#)&)("*"$"("$#!+#&)'$&&(!*"+*!+*""!$'"'$$$")+&+&(%("%"(%%+$!&!')&)"+%(*)+%!%'+%($(!!(%(&%*!&$%!()''*%!&''(#'*%$&(')*&%+%'(+*#')!!++()*%*%*$($*(%*$*)+!)+'*(!%&#)%+"(&$&$)))&+&*)*'$%!'**+&&(+$#)'(+((""')$&$+*)%%'*!#)&(+!##")(%&&#$!+(#&'&$'!!&*&)&"$'#)%#&!)&!)&$%)&!#)"&+(+$$)%#&'$+)(+)++%!)$)&("&+'&$%*"#)(#)(+!$"!)%'))&&'++)+#)'&*)))('%!(($+"))&#$")!%+$"!&&(()*&)*(#%#!+$%**!(#!"%("+&(++&+#'
@r2656
TAAAACTAATGACTTTTCGCCAACGACANCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGATCTCATTCGAAGCAGATATTTCTGGATATTGNCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCATAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGT
+
;8.<39&8B$EE(E4DF:50$E07?;$F;A!<6D();4'!9D8<+?$H922,G@'<5?:#5;AD0?=1?2.#6F&!15@@0;;8*A;/;/7H7?=&)<#"4/=7;)7;$%$!G:08>G!A$<95=7FD0#!)=<@45-;=AA763(5->+%F"9"(HC&0B"G8%&#A'1>GF,-+'%$F%-=-!0?-!1,)=&4A,%(D-$:@0,$56E:8?+7";B@@17;<B""%*:E;C63G3)44<!B9B#286@=,>
@r2657
TTAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGAG
+
$3D.!@?28%!4&H@&A1,$?=?D$4".";/4$/$0A*G/8."3>?!.D2G%365;B2$."?%(=98HDA#>B,D/:%6F%%/8BH7E)H2:-'4D?%HF1E53;+3(A,7@!1-/97!&2B)1.0/
@r2658
TATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGTCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTNTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATGTCTAACACCGTGCGTGTTGACTATTTTACCNCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATNATGCAATGCGCTTTGGGCAAACCAAGACAGNTAAAGATCTCGNCGTCTATCAAAGCGCGATCAACAAGGCCATTNANGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCAC
+
4(#4G$%,@%(;'6%:?'456/@;+04C(+(F<:6D(=)H297H4'6FG&90F))/F56+A&G5!C4?72(77*BF>!EH@,34%0(5@#9,5=HG#D-275E*?CA/"@$,;,1"FH9!:)=44>7E?1B8#0!6>4$!%7.2A5CF8D9%4FC8CE:+)?8H+;-@-%G#==()E*%64698!8!D,H9=:,##55-F!)?4@3:C83:.D*4<B.9G3E4&1@4'#)<=8/0*';#7GFF8+&*&"%7*5//./033D.9C&2+(!)=9#!5E)75!3-F:$(.;&2H3)A)9,$1B5>C:FD<9/#AC+GE'-1>D<!1*/@!2=9#B7G0,H.1$;#32+:@@A$<$H.!)+-.!E(.*7$1+CCA$:F,85FF$$6%:?9&B"@73-62<-'G=57"D&@%(==?$+:"08#$94/=71GE&#3=D!+7,%:BFC;!H'8,?A+A#;!67:;5;04$.,3D@814"9F=&=07(F>F')6(DH9H>5/&$:,<+F*?'GF6C=$@0G?G6B((/+968-@B<470D-72"A*E
@r2659
ACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCNAACAAGCCGTAAATGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCCCACAANTGCTGCGGCACCTCAACNCCGATTTAATGAACGCAATTTTCACAANCAATGCGTGGTGTGNAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAG
+
:>8?0$@3F2/H'GC"F;6@6,B,+10?&*.D$)(1>H/<!=5H=+4#!A6,=C*A>@E'<>E.7#10.)7.'3B#E)#F4>-CFD5A1!,B:1?6>(2!04:!!B,--2,4/"C:,;*!46#=H223+./<G7=41'@F3.AH57;$*!*44.!)&?B;!?1#'!!#8?%G>2<=;,%.E/$&%5&G:C2340C1F=1:(6A/5,"?!H:#C44<$G&<-$G1()(-<%%4:>#6G=31;/1:/AB*=41&,E!DD!G4=9GG4/C$F@2D9<&&08?//8("0@'A>5HC-8;CCH)F2&807')0<.C>>'"/3E?2<:+D;2:<AC8D3C"=2>EDH+(.":H3#66<1*!#<7D9(;&1+@4)52%>&H("BE@4&,?$7&89,G6)H73E@7-$.5D:%*,FE'4;CH#,>068B!'&1=%
@r2660
AAGAAGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCNTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACANCTATTTCAGGAGTTCAGCCATTAACGCTTATTACANTCAGGNTCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTGGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATANTGATTCAGAGGTATAAAACGAATGNGTACNGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGANCCACAGGAACTGATCACCGCTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTNATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAGAGAAATTTNCGCCTTTCCTGATAAGCAGAATGCCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGAGCTGCGTTACCNAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTNGCGAAGGC
+
'"(*!"+!!)'!"$#$+#&")#"'"(&&*"&!!%"(')(%)!$##)$$')#+*(*#)($"%*)##)%)!%+#*)+!*+'!)!%$&$($+$+#!&%))'!))!*"!+''!#&!$)!()"$"*$(#$%#$'&**%!#"*#*("#%)'**(&$$%*)&&!+$$*&'#'#'""+)**"("%'&$&%&*)#)*%!($!'+(*'&+"#("'($&'%"%&&%!)"*&'#+#$+#&)&)!()%$'(!)+(!$'(*)'$$!!'*))+#+)*%!%!%%+&*#$!%$"'%&"(()'&*%#')"&$+"!)(##(#$"')#%$')!+''&&!%"($*!(++'+'$()*)**&'$$&'"&(+&'(&!'!*'%'"&%))((("($#)+)(!%!'"("%*!+*#""&)"!&'&)&&!("%#'$"''+&"&&#$$!%&))"(#(#%+#*)#%#&*&'"!#""))'%"*)(+"'&"#!((#(+(!'#%""+"'!(+'*"#!!'!&+&!&$&&+'!"(!+!)%#+$#&#'$'#)+&%#'%*###))"$("#&+()$%+$'#'"&)$&&%*%)$&!'%!'+&$%%#'!"!+%%')!%%%#"+'(%*#*&"!**)+!+("++!$%"'(#(&)'&&'+&*(#"*&#"%%'(&+$*"$*")$#!)'*(+(&$)"'(&$!+)(**!#'"+')('#*')"$*"+"((!"!%"*%)$$#$)"$'$$&(+#(+)#(')%")$&%!)$("")#"+#")$##("$'(+)##%"&#)&*($'*)$*)*!'*()'!'*)*!+&$)((&)!"%((!*'*$*)#"+%('"$%*!&&%"%(*"(&)*(+&""*(+)+++'*'*$!%($(&%#+#')'#(#''(+!(+'()')%))*#!)
@r2661
CCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCCAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCC
+
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
@r2662
AAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCNACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGAT
+
=8,0>7F>3,(?;4801D(6(&D=B5(@=3AH&B5*&"4!/0%/-!$E>HADB-H'!=&;-=2/8%GG+90*3/#F):):4*1#?G*?76/&B?.*>30BBDBEDHG00CG?B0307/&<A9@3.F'@F&(6>=4:C(0;!4F+D19?89/60@%:"DHH7)CE3):F3F=$@%+&;F&3'BH3/&)844E')&ECA!1:="587A%)C&D#F7&HEBF=>5,*F#/4C#1-48#;875%32E!,$4#&3&0<"570!01#:7':CD5;H@FB4E<@)EH--$@65@9H<!/BE4#*8583>&&>
@r2663
GCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTG
+
2"4;,7?:=#)/<3&D>/'$F3HD:D-<0;;6(HA7;9"6%%@'CG$,A
@r2664
CATGTNCNNNTTTNATGCGCGGGCGGCNCCCCGCATCAGTANTTCCCGCTGGCAGCTGGATGTCAGTGCGCTGCNGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCNGTGCCTTATCCGGAGAGGATGAATNACGCGACAGGAAGAACTGGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCNGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACAGAGCGNCGCAGGGGATCTGCAGGGTTTTATGTATGAAAACGCCCACCATGCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGNGCAGTTGCGGTCGT
+
''$'(%""!")*"$%%'&''!!(%)#&")"'$+)&%+$!%$)+&'&*(%)%+$*)#&(()!%+)!")*('$)%+%*$+$$!%#&&+''+!&!)%$&""+""+')*&&)&*&(!)%"($"#%'#(%+$#+"+*!)*)("())"&(++#&%)*''%#!$)'&&"%"+(+(+#)&&*!&'%*!(+&&'"+!&"+"'!(#"#'*!$!*)*#+%(!'')"()"%%&#(+*+*#!!#)")(*+$"(#'&")+$$#%&%$#&+!%)&$&*#%'+'$$)"$$$$'%*#'*#$"!!+(+*$+"!(($($*&*$&*"%"!+'%*$%#+(""$!('&!&$'"(!*!(*&!''#**#'%'*#*!)($+#+'*'##$%#%#"%$(!)$!!&+!!"&)")&%(**&+"$!'#')*!#')%%$#)!#++*%")&'%(!&!"+#+)#'!&&)'#)$)#"($)"%!(!$!%!(!%"*%%)%('#'")(('"
@r2665
ANAGTCGGCTCAACNTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCNCATCGCATTCATGGTGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCC
+
#"C."H+4#?!F;>?C=9-B'&24D+HD+(3(.>EE&B;/"61@,<1@11%B@4B0E%-=F$+5>#BF://#@!A"4D=3(4:?18*@F$"$&%1,=;)4%6,*:G347@6?@?9,6+"06;2$;,64FG8&%075<,3!83715B7+@;&</H:*>72=#07.=F/>HFDE..$'E-((*407*:+'B5/ADBB+>?+)D++"+H?""G26?"5+%!+'0%&D'6,5>9:1/@EC!!,/0$*):5;%;13#EEC/9-A78>;D27;(.;%F6C+=>406GC%C%*+3:B8B+,.5D@
@r2666
GATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATNGCTGCCGGGCTGGNTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTNCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATNGAAGCCGGANTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTT
+
8CGEF159);8B((9,*'2E:+?#1E=("6A5".;H@&&/=E)B=;$&%.8-*+3901?48"7)B.)*+C/=)00D0("G$-A=,!.,)-.16.4CE)3$25%"1=2%"5=."*"EA;)=''*;F2?<8.AF*#E@5!#7>&+CE/FA4#-,AE>5+!&:>"@5>&C/29:=+H"E08?4G1G?,A*;4H&"+3#E9'*#2D*5:<G=B;;C5%6-(A5!00@G;;+A&?G;*;3&635D$<(&4A*""83'G="*G$-3*E<?%=G)@:@*0%7D"FGF.H4=).7&"E:>"5=DG8F=8;()'#GC@!H>4*+9E<15@@A&9+73(C),CE(,G,57:>B;!/'!@1$H"8F?)-%403-02H=2+(506DE/<8$-7+,-.8@%7$FE#9!?*>9'2=)<6?)D$DH<;F+;*45"@!>C%?$=,9<>5,C-95#0F0B@:><8:DF5,+G@)F2>E%F&&0+#@'
@r2667
AAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGNCATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACGCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAANCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCATTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATNACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATNTCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATAGCGGAACATCTTGGTAAGTGCATATTCTG
+
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
@r2668
CATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCTAGTGAAGCGTTATTGGNATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCNTATCATCTGAANCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACNAAACACCATATNNATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTAAGTCGGTATTCAGAGTCTGTCCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTNGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGT
+
$*+((*&'#!#"$)%"*%+(&""&"%%&!!($+*$%#(%&)&%#'($''!&'+*)!!$!$'#&!"&+&("#$%$)%$%"(##"+#&"'$%)*$)$))'#!#*!&)%%((')$)#(&$#+*&&'%(&((!*"%&!("(!$%%%%*('*"!#')#+($%"*!!#*(%'&%!(#)(+$%+)%+)+)(&%%(#%#'!((++'#$%!$%+(!*###%"$**%*)&*%+*#%)!++!%&(*!&(!+&$($*%"($(*%)*%$)*##")##+!*")+!'#%'*#*'%'(*)$!##%&!&'(!#"#$#(&"+*'#*"&%"#+(#%!##!+**(+$)+!'!'#+$!&((*%&%++&((%()'(#+!&$%'&#)#$+&!"*$#'%#+!'($+%#+)(!&(%&"$%*++"#+&"##++))"'%#'*)*!!'&+()*++#%%!)!%#'$'')$&!+(+"#""#$('$"+$!%##"&%#$"&()(!"*!+&&!&#$#))&##***+#'"&"&#$"(+&$($%"*+!$$$!!)%'"#$"+)'""+*'&'(#'+"&'('$&*!'%&$
@r2669
ACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTANCTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCAC
+
@?H%-C.G-3B/-!>!!;)H>%D49E:9:A<<1<6:B;-+%$#";9;*E(,5##EA@G+784B&-E)G4'2@7$.G46%-#93&/)"%(+;$3!,"5/B&/+!9#F"B';7=)=24#E("14&/$7<2$31./*+3$11=H&+;$>@F%FH$&11&9CD6&@B21,#1$.*5?H&"@0=(1380'B>D#9)5=GA<=,$*)&2<D,>/$D2#,/$BD*24@1=#67=AC.@(1/B."$6!HB:&(8-7$>G=G#/*<2A#*8@3'?/A7G560(0*A!F;B#/#6#.6*'%CBA$&76(3/$H+"$-2&0D%C9$52C(C=:=/>+@;*"+A-%7G3<#+H@20$437-&&08!C4F,3D
@r2670
ATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCC
+
3*8?$@%-7%HA5HG@/,=7F1.,D>D&2?'3"$6,HE@GHC@7>,<G
@r2671
GATGTCTGACGGTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATG
+
87G/*'/*C7&<7C9A(21E279(%)0>1;1%$9F+3@150?C@(G::4E66,(:!<E"C":/A-$#/G=-(
@r2672
TTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGNGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCC
+
4H*;#)?*6BB(HH7?4*CH!8;"4,8@@C8=5.(!+3-2>$,)#08?)AB;A(-:B6A()1FE,6GC',.<8'0$>9/G:FB&,50023+$F.::%7:C0DEB#*251(#1*1HA-.2-9-"1B1><8>(8=+2EA+';H6(?-"1048FF;4<?563%?FED@%;.G:-38&!@F=&C&C9+3):FA5DF7?1=$(!B2#6942$:G940,87:$=66E"!E#B#H46#0'$%7&75)@%-0)<@!4!5==9@D*.>)317C&0#4+E-5)=F5B9'"'$)(8:3H?=.A1E/@)CC*#=1H%B=F@E!9!B801=B7G1,3D*F987E!?(CE':.0.,,&%+=D(=HC#H#&FHH24,.0@@6@
@r2673
GCAGACGAAGGGGACGGTNGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAG
+
==C+9$'DDA0"1+4C)B;";!%/FEC$E?C:(1(E$BH&%$*E6#66,!9BH*"G9&&(*;9)$EGD&H;?9=D@5@6+//,->-,1)'&%@F;+-4+.F;/!#-&8G1,B:'*#>0(5>912.>(,;=.AH?".#B60=!#C+##<>D>?17()EH1DHC?(%DFF4C5GF:BAA<$1*'-/?=<4D#6&.,><*7<&)6"="%DF-5/$%G
@r2674
CAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCNGTGTTGACATAAATACCANTG
+
22&8(1).*$$H=C/#!*6*$(@+%*)%D$$(+;;=,7)3>@4*4+&%F(4A17?#%9>D$@-+)>D:9%-#55*,E@4FB'64/*0*4".G;A.F'<
@r2675
TAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTNTTTTTACAANATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAANTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAA
+
$6##D07+8G.46"!E++&:A($'=&:657+8*$1;&*$*5C8:$69@HD0?'=":BC,=-H32)+F4!%1B&,8@C;<?&B#<C:,8E"?,31'%59B=%B$@>.(EB65CD0:7D&:D$71B?E$&6$)<6;G/9A$*922%9HC;@B90!.0,H,CB)CHF1?G+)))7(%EG@=@$8@9'/D!1-EDCA6=.!'C/A$E&<//E:-G9/DG+C<G?=G<%"*3#-<4-,/2C+"#FE6=4<F"%FB+8*6'<'$4*!%(-52+G#+@$/G;2>D26A-H&&HG.0@%3%A4&8"A%2*2D1%<7$A#3,D"!B+."5-'*E)%DECC"""8#2*;5-,0'F/7AA38?3=BF6
@r2676
TCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCGACCAGCTCGCTGATGTTTGGCAGTCCGGCGGTAACGGATGCTTCCTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGGCGGGCTACGCGCATTCCTGCNTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCNGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCACGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAANACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATNTTTTTCATAGATCCACCCCGTAA
+
E6)8<B*24'5@E3953G#+6$(.6F8!?<36;D.''%-"0?GB6:.FDF+>!*%+=<$(#/%CCC")?3C9$#9B&.B/*9-GEG@$':E",2+9+>%AA)G54&C(/'#&+H5D5$A>CCDF4*/50/"1:-3:4:!3?C6428@,)C--8;25=C&E%-(+".=B=9D8(//,<='-(.3?8E@<4;>F),;'>(;E@;'HD-A;2#267&?4-)062DA@2-!GH)8%A!9"+:<G.9<F?7!<$%/"5--;7'1(+'3)0"/107,B"G=3*%)6H#(43A<D:CE26=9%8A::B<#9G<=-(-/"A7-"B#-88)($)5*H<$?A77H/!39!E$9@!!#C(!7=G,#64"-@D!?($'5C%#>,&+E/E@6-E:,6A*DB(DF>:9#'7#0!GG(/B:??;D@?+643CD7!-F8>HF@$01CB4$.0#0(/
@r2677
AAAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGAGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGNAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTNCTGCTGCATTGACGTTGAGCGNAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACNTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACA
+
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
@r2678
CTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCANGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGA
+
"3*#2<4!79F?'=&E:5$9B7HF13E44C'93C%9?'9<5&!21FH1*/B6FD+15!(9'*@HF$7E;8B48>H>>565"'=-483C:@.H$GF"=A<;'*<G$=!3E*0*!?):>E
@r2679
ATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACNGCTCTGTNTTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGNGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCA
+
(&.%49/G*3C35H0*)7(:2;..-#5'A1@05B@B<6.+9-HH3A.':+1D7A*3#DG-/66A?-.94F273-C#)=/"B(.@A;0>2H1#E=::EH3)*05-DE3G$/!'1GBD>0*%8CC>#0E8*=,6/3//7'3F8(>(35,@F01!+(*?79AA"HE*,?24>F9G+6A<+!.8(*+!0<$(!C)0)'B,7G72!/>##'2$B0449:%%"#3)0"@B2B@4?H?@'-A&5HB/<@C71&1**2G/9)/-F#6G4%GC6,A92DF.*9>A8G>"#1?<D;,G(!-=8>$=3/0
@r2680
CGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTNCAGTCAGAATTTATTGAAGAAAATCTGAAACCTATTATAGATTTGNATGACTTCCCCNATTATTGGAAAAGAGTTATGTGTCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCNAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTANAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGNAGTTCACCAGCCAGCCGCAG
+
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
@r2681
GGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCNTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCCGTCCGGCGGCACGNAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCTGAAAGGCT
+
)$+###)+&'(#'"!!&"*+##&)%)!"!'$#*')'(($)#!"!%$$(%*#%&&)()%+%*&%$!*%$*!)+&))+%"('!+("*#%!+*)%"*+'!!##"+(%*)!*"+&('('#%!*)(%)"$#))+)("%%"")#+%+"')((++%"+)!&*$&++$)&!'&""%)()$%'"++(!)&&"&'!&)#+$*'####%+!++$!*)#!#''!)"""!*#+%$)"!$(*%+)"("")*))%$"$%$!"#%!)'*++)$"*!#!$("*#&+%"$!#%$*$+'$#!"&*)$"+$$&+!)'!+!&$
@r2682
ACANTGAGTGACTGTGGCTGCCCTGACTGTCCCTTTTNGATAAATAAGCAATACCCNGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGACCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTTTTTTCGTCCCNT
+
(%(%*+#(&$'&"%"*!"#'"#$$$("))&#!&!%%%'%++)#*'"#$++*#$*%"#&$##$%$'+)#'""')&!)%)*''(#%$!$"!%!!*(#($()!"'*(!'*(*%&*#%)&%*+!+!)$)!&'+'"(&"#(#"'$**'!$&&%)(*$($*"+()'&''"'$+%$%!'!(&%'%##$(!+"#&)%%'"$*'"$+&+)&&(#$++'&)"%"$+)&$##!*)$"$*$#*'&*$&*$!(!+(&+(*&*")')(%)(+&)%')(
@r2683
NNNCNNAGTNGNNANNNNNTATTAGNNACNTGNTACNNNGNTATNNATANNNANGATGNNN
+
""$!$#"$$""!!!$!$$!#$#$#$!$$$$#$$"$""!$$!!#"#""#!$!!"!#$$"!"!
@r2684
GACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAANTCCAACCCAGATAACGATCATATACATGCTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACNATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCNATGGAAGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGC
+
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
@r2685
CGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGNGGATTACAACACGCTGATGNCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCC
+
4.9=@7)9<6>@2C5!F>@>;D?(6A>BA83C!1!3H!H98&B9<-"/@F),0B)-5->8B&2'/5?!'8'0/-12<,/;=3&+$5=!.*&BA'=!?<>GG,?1=%/:4E##F$2610#0*;FG@5(D;F7#9("=:#4G0>%)(4%*<28@@/H=55=-D745)=>B8)E'")C0DG@8'A*(HC&*82)=75A6AF?*'9=<%!?D
@r2686
GATNNANCGGAANTGACTCCAGTAGTTGNCTTATCAAACGNTTCGCNGCTAAAAAAGCCGGAGTAGAANATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCNGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTANTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACNGACGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCNTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGNCGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTANGATTGATCGTGGTGATATCCTTCAGGCNATCGACCGTTGCANCAATATCTGGG
+
'%&!"(#*"()&!)#&'*'"&%($%(*!!$&+'&!$('++%#"(')(+#(*")*'(#**))%)&)%(%%&'++($)*#"%&&')''')'($#!+'&"(*"))*&**'*"&"($('(+*$')(+'+(&'+!#&%+'('!!$(#$%##%%*##$#!%)$#$$$+(++"'&)%'&!)!%&)+*$"'#*)'#*!!#(+#*##*($(!*!'#&!)#%#$&'%+)!"%++$$&""'&"*(&'(&!!*(')&*)$#$(*&*!($$&""$"*)'")%&+)(*(!#((!#(#)!+)$""%"+'$)'&"*!*$*'+)#(*!""#"(')**#$'(('$+)!!'+!("+&(+#$+)+!"*&&&"%'#$$"!%*%"##"$++''%&!'+*&&&!#+')+*"#*&)$$(&$##")"(("$*&"#(*&("$")#%"''#'+%%*&"*"$*(!!'%$!
@r2687
CTCAGGGCTTGATAATCATTTTCTGAATACATTNTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGCCCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAANGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGATGTAATTCCCTCGNCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGANCGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCANGCTCCGGGTTGATATCAACCNGCAATACGGTCAGCGGTATATCCCAGAACTTCACAACTNCCCTGACNAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACNTCCTGCCACAGGAGATACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTTTGTACCGAATGCCTGTATAAGCTCTAATAGCNCCGCAAATTCGCCTACACGCATCCTACTGGTTGACTGGCCTATTACCACAAAGCCATTCNCGGCAAGGTNAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATGNAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCANAGCTTCCTGTTTTGGTCTAAGCNGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTCGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAA
+
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
@r2688
TGGGTGACGATGTGATTTCCGTATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCANACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCA
+
CG)*F2H3G*@=&9.2+'@;H*1(/$DH9<)@($080&1;4)18''35A<5E?2A5B3*>CF3%F./;@62%!B0)'639*D9>@;"@7H0=8A;:G'B4)*?A=!#,<&-8:/%C,:60EC"AB(2*+'#"/&$$FB566.065?8GA."6:64"&:)&B=$=AD+/"09)4E@+0:5#$H-7+"GF:"EB'#H6.5:H*66;7>F!@?
@r2689
GACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAANAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAAC
+
DC.!*263)F8!,'%G+2'1@)+DHCBA%(8HA:(#7<*=*$-80-,.CA(/&#7A!A<%BE//2=B/6EE*=(961$=:G:BC.$4318'=!H!8?;'"/(H/:D(<2-B=*7618?B"8E3<3+!&/90)*F/&0<0!&F.D1-BG-30*9C.21"HB((),.!C;)F!C2*17"73/61(A<)2(95;386(C)2*2&:75)1#=!-4%F6<E*+/:0*&.(/7+1:B+A8D(A*CGD89?:#D9"")0*2A*"#*E95C!>5.*=G>$H,233$&
@r2690
TNACNNCNGNTACTTNTNGCNNTNANNNNNNTNGTATGGTCGATTNNGGNANNNNANGNNNANNANNNNGNNNNNNGGCGCNNNNCGTNANANTNNTTAGNNNNNTANTNGTNNNNNCNNGCNTNATANNNTTTGCCNANTCANTCTACCNANAGNNCTTANCNNNNNCTTCNNTNGCAATNGGNNAGNGAAANAGAATATNGGAGCNCNNNGNGANTNGCGNGTAN
+
##$###$#""#"##!""#$""""!"!#!!#""$!##"$$"!!#"$$###"$$#!"#!#""$#""#"!#!$"!!!$$!"!"$!!!$#!$#$#"$#"!!$#!!!"!!"$"!"$$!#"!$!"#"#$!!""!!!#"#"$""!#$$!!!"#!!#$$#"$$"!$$!"!!$##!!##!$!!###"#$!!!#$""#!$##!###$"!$$$#!!"$###"""!$!!###$$$"!$!
@r2691
GNTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTNCCTTGTTCAGTTCTTCCTGACGGGTGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCNGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCNTGTTGAGTCGGCTGCTCAGCCTTCTTTCNGGCNGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCACTAACGCGCCCGCGCTTCATCGTTAACAAAATAANCATCCTTGCGCAGATTCCAGATGTCGTATGCTTNCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGCTTTGAATGCCCGCGCAGTCCTGTCCGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGACCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATNTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGGTCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACNAGCGTTTTGTTGAA
+
*%$'+)!$*$*$)'!"#%'$+$)'%')'$*$%'#'$!'!!&&'$!&%(")#*"&*'**()%&%%##*#('%$)')'!"#+#*#'""'$"*!&&''%++#)#'(*'#)%)++!&#)*$)(&+$%+++'!$!**"#)*)##*""'*!$'+(!"")((%(+*$*$("%'+"""!*''%%+'#!$%!%(+*&#&)#$%*!''"(%*#'"$!$+()+'!!$"#!%#*!"''#)**)%*"*+''#%!&!&!+!#"*(((+'+&))"!*%&"((!)&*&)'*$"#&"(+&$'%*&$$+"*##&**()$"$$#())"!)'!&*%!##"#)($'*()"+*%+!$&)!$'"&"'#!&("'$)!$'&)#*#%*+%'&(&$&"!*(&&)+*$#!*)&"$''$&&&!%&+#(*$*"+"*&*)!+$&!*!#)"$#+)&$*(('!%)&'!'*'$*%%+%(!*+)&!!+&&+%"+%)+*+$!$&!(*%%(((&"'%$*%%"#%)!)'"%*$*)#'&('*+#"#'(&#+&&#&+*%!(*)$$+()'#!)()!#$"%("#&+%!)"+"!$'$&*(!)*!"$"(%%''(!(#&+$(!%)(''$!**"))'")%*#%&'$)#(""#'$)+"*()%#"%$#$+#!*#!+%*"*)(()**+%*$%+''#'#"!(*(#+(*+!'""$$+*$"("#*+')$##%''#$+*%%$()#(+'!*#%!!+#%$$+%&!#""(((**!"(&*("+#*#*'$"%(%!'((")&(%&#*"!%''#**(&)#*!&&%*!+!&+"!'&%!%"$(#"))!)*&"!$(%&%"#*'%"'$#$(+*+(#+(&&(*!$)"'&*)'(**(($%+*"$)%!!!$))&(#!!&#&(&*$"#'%%"
@r2692
AATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGNCGCTGCCGATACTCCCGACAATCCCCACGATT
+
6'-@'8B2.C20C/?!&B/=961,>B8CA-E8-"4@9-"=-5&7?$$-7,2E3/'8/$="/+.3.BHF240%79/CF.,+2*)B''+;+&+@.%"+&8B%B*(A4"&A,
@r2693
TGAACCNGCAGACNGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCGTCAAAAGCGCGCTTCAGTTTTCAGGAAGC
+
H&(&AF:-H#(;B,5+:H7E5)&A43<0!.(GEC:*DB)1A4G.75()F1D5,45-@81+/-==4@CC3.B8!7D8$&&(4G@998G.1"72H7;+'G-82?+'70,<2"$27:1(B2532:H9!BB(%#(%H*25D6.$D@H68FC9-B*A#-4?GB09A"+*3(-BC4/@(;(!:(=(4C0##!+6A124+HE01B,2H/;H2F=,C(.:91=".0F.9>?7&>(B7?BE)3FF=/0D$=#10!C463HE00>?19A2A21<?.5!4="H#AGD/!<@DG/0?.:/F$)+1B>>@5
@r2694
NGCAGCACCGTCGGTGGTGCCATCCAACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGT
+
!&&+$!*'%$****(%'&'(*&!'$((*+'*"&'&&%!%*"(%!"!$&!&)+"!##%'%%()''#'&)!%$)&#%#++(&!'$)$%%%*$('$%!$'+(%$&'*)!'+&&+%((*)+**&*()(%')&$'!
@r2695
AGCGCGATCAACAAGGCCATTCATGCAGGCCGCAAGATTTTTTTAACTATANACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACAT
+
@*?/@:@C+9<A>8)&1B+#5.#3H!8?<#";9G75:G0H*?2@A38?/@?F)-!++?*#HA@HH</62(4AA+**D2)E21(/GH7*(3.4C>>>:&DDFF-!%%'$-=A6DF#@9C0@D'(7"%+>(,A*9$F.!48.
@r2696
AAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCC
+
DA)"DC/'8<9"7"B+>!=09051"CHG'H%>+&>/1B5"2)";@+/&F6G(=@(&('",)#H((=CC;%.6A0F-:@*:/1C6+)(
@r2697
AATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATNATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACAATGACGTAATGACAGAGGAAAAACTTCACCAGATTCATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGANTGATGGAAGGATGGCCT
+
'',;09(A<8*#0#(%!>B3+39E'?";0>94#'60:@)";C#1/0#$H9*1.CA&"*/6G<<6D+07F!=>@B4;./<$F$-'7HA1+@4!E55==;#1(=7F(=0H-7!=&+(%7#25%<7-5F7=+)5*D@!/6#H*$B.10<?4?H3,,/7-9#A,(7EG6941;23?<,,1FA(;1B:&A78<-%&!=*04.:C57;;-+4>$=.A!@-5/*)H-'?>C9"%!-."5,G2>@0A,8)>5@8<5%2/E35$'@0<'#:$-G74H$@G5!FHF?#%BH0"".6G0(E!*$85AA.8B"/HH8&181:73/21%A<D(&"/D-A/D0G+H;$)/';?H)D):0BF(7"B0-@D.7G-@:H%A:692@F"
@r2698
GAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCCCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTTACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCNTGATACGTCCCGGNAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGNGGCTGATCACCTCCTGCTCNGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAANCCTTACGCCGGACCACCCTTCCGCCGAACGGACTCTGCATATCTTCCGCCATCCCTGTGACCATACCGTACAGGTTAGAAACCGTNAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGA
+
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
@r2699
AAAATATCTCCGGCCTCATCTTTTGCCNGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCNTAATGANTATATCCAATGAGTTAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGCAGCTTGGCTTCTACCNTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATNAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTNGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGCTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTT
+
7=!C4HH@6DC94'CG@19-,3=<0#./:0C2+5%1F*".096'!-+:&7$.#@("(8*)0<)-4H3/@0>#3*4,@6<?HB=G/$"EA>2@D9*9'7;56B()922-?5D:%@,+)*'34@C;=6(/:;/<A@D'><2"6G,&#&>8A#+<C=-GH=;8>9:8-/9)<8%6.2$;73'7)E,'GC7,>'6'?0'-EAG3:B4+659A<HA?+/>G;</1(E/?97>+(G&B3G:,4+5@8'933;*'005D;#B9A42:(='#0GC=GGF2/)B>+.+*/=8:.(:)?6,9?E/H248*D.@),0'>H8E0';D244.+;.9<@(*=8FGD=?D:+,"6(<===($(=/@)B2<H.0B#4')D%)%84G,CC,>%8DG*8:3&@?'C5:*G>)0<)(<14DH4F?9(DCD9*-+,76!G'$:$#-()'$)50CC9;,BC,-5%0H3B;HC%77<2D*$)/DBD1@8?(&%E:0G'48E194#3>7%*<D1@F+3+?(DB)8?/DB4!&#4@E9,+>-H8C!C"A;A#5F41<),<6D5+5(>0534-:'E84."E'(2D(0;3:7'E%AHD+/@DGG?89!$-0D&/1-#"&DA/!/41:D48179=D6,E2$)"&5E*4/219=@C9%"CBF-:;/+0#9/:,>./9=ADDF60@.EF,%%;-02'7F8,!42,D;/;$B&0AD6.)$E*B#E5;<381&#A)))
@r2700
CAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAANAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACTTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATT
+
.@HB78?-8+@(D@&)H,04$.#"G4(0G?%!6!:F3D86/$C;:="%E:#$*(8>3?.B2C!*=B'CA')AB5D="G1>C-<B@0E@E.!321ADD;'>?,+B)5'G13.2#"D1C<4+CC(E.),=0(+0H7C3=,64):+(#!.7?='#>'4/>8E-G?+;087G4=!.1:C'-5G!'.7A>%==C6"B=:**$G&<=)0@-";%
@r2701
NNCATAAGTTCCGCTGTGTGCCGGATCTCACCGGGCGGCGCTTTGA
+
$)=!/5F,?'C62#B4,*46D8E;AHE'?8!=9B+%'H-8%%"8%%
@r2702
GAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGNTCCTCAACTGTGAGGAGGCGCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGNGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGAG
+
A5-),?AD9E5-@576&E>>&*?@H%"-EF=+45#1+'#"9(+#9@);1*%9;@$?$'019BD"@C<F(;)2*C==B5-1$)4&>>(5D"5E==$6B@)1@93G"1>4=621<!=*<67<E?,+9E)2.7C1;<AB2C7'-4G'">/;$57C:BH=1E'H87)B7*).,8F9>7#*E-!B#?-A?!6/21>&257AE8E@&*$95*H:4./F<>3063;#AA?=@:#,!/+253H>"2@8G4")@>.;'/#0A(2<DF',@FAEF&=?.8;:E?&!%)A=3B28+6E.6&:='E;8D1H#"!;"F1@F38:<5#.7B6ED;B+C?2,+<G=4*1=5G3!1=
@r2703
ACAGGGTGTGGAAATCACGATGATTNACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACNTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATC
+
.(4'!7E<A5:7<&C:-(>D5(#1&>)*=5FDD55D1=*G./201AC$5G3=(/@08H'/&@@'*<1D.A1!-BH"5(H7@64**BB,28/*9&<//&>+45(%EA#.1.!HGFFB(3-!2!1;-#/!26"57)3(D/;@/71H//?46+@B>$G'3-E9C*0FB9<*5E2D@HF1H1$"6?$9F)DF'4FFF%1./0%&;'"9H0-%.AGF033C0/?'#%EH9;0;0'D<@F1'9-<6C@A.1H31A?/GDH@A"0?C++%'"HH;5/.9GB14<)-<))-88/GEF2A<F!
@r2704
GCAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTG
+
#(>$9-&*;GE)>501)#;,<29+=G?7,,1G%GE5:+4#68*!A@33H?7,
@r2705
GATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCNACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGG
+
..'D6-*<.A489B.29C2BB%E10D4-++*=.08>0?;D##G&@D6AE6G;'C3'B',(.??D5,*)+93;%C/+2:3=!/.2*4#0F1'0?&/1(
@r2706
TTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGGTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCNAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCG
+
2;>H'B-(E/=#0.?.&%//<-<8;+:F/.*F.E,?G0+&,-FA!4-&8,(-('3!"&7@A17@9%/>C@3G83H3:G/=53$.)=($A4=58$:?-@/G<4'E=(<"C",*'&>5C/"':@89/0&=)%2)9A@-H?E;/;4#C=E4@>A(/"5'!9-2'(9%0)C*%,2:8=F2.:;-B8&CF099??<?H$8?1B>2?C!2?/?'GD/-0$)4@)3F!5,)7"7>1A)(0F##)A61(:"#E-F;*4A'5,6@47B7D"9"C9"E)%;<%*C6"/7688A#3->5!:=0+8D34,)'
@r2707
TGGAATGAACAATGGAAGNCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGANCT
+
E61115C&'B.64/1/$)-;5-61;5F089<H(<,G)@?0#27=&71B&)#!"<#E@"/)GHC'%)5-'E(+=(>
@r2708
AACATGCTGNATNGNTCATNCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGANACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGNCTTTTNANGGTAGNTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTGTCCCGGTGCTTTTTGCCATACCACGG
+
'&$%)'#"%")!"*%*+&"#(("'*(#&""*&+'#+$"')!''%+(+("$)*&!&%$&(+&""!)*#(%&+$+!*)'%$'+((#%#%!#!)'!#'&*%"(!**%!+%!+*+)')"%$#"%!($($('!&(&!%("!")#*&((&''"(##$!)'#")'$'**&'*&'%%'%'++"+'*$#'!'+(&'((%&*"!*)"'%'!#'+!+*%!!'&*'"*)%"'%'**%%$%(+!##$!$*!('+('$#&%&*!'()$!+((++#%$)#$(""(%'!((*(&&#$'+#%$%&+'%"*""&!#*&&$!*+*%'*&%'*)&!*##)**)"!+#+&"((&!+#("(+%#*'#((!!***"+*%)#!+&"!*$*'%#"*(+!%+*")'(+*(!$'!$$%%(')$(!(#$())%*$!)*%%&
@r2709
CGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGANAACAGGATGCCGGTCATACCACCGGCCC
+
BDE/2H-89B@??!*$3>0D:+&!3(&%?)#G:842:''(8H)*@EH'A/589-B(GC1='"&$"0>F-6<.*@,,!(@@3#?)11&89.;?#@*&G0.5#0*"G1HE>:8";+$<,"8,@GB';<?A82."<<==1#4%'!!95-!57629%9"-9H7432*A8#9!,1762=&..C!H=/C8F'!;!$;%H"+1/5ACH)!E/617"B*4#0GD$4GE?D'G"D5+&01:'"5(;G,+1+<;6@G)9=#3-!"6G(+6*('9&#,2&#HH45/)F@3(;!H9@@;45E%)B;B7)C$4*%"@DBGG+*C383#$<,!;101$7<78=:01:B&;#F<47D<7H5A'D,5&D11"+,=F#"8:$-0#:A.AG4'F!:?.$G?
@r2710
GCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGTCTGCGGTCAGGNGCTGCACCGCTGGCGGCGTGACACCATNCACCGTGCCACTCTGTTCGCCGTCAAANTGCGCC
+
E3E2-7=194D?G"196C2(%,)*3'&)(H'B-:&3=C,G>>3;)1.H56,8,//<0",1"F+"6G-DD.<D)81#5<)4F-D!5AE!>:!-)H%(A-??5BB:7@;&&()<)
@r2711
ACAAACTTTCGCAGTAAATCCCATGACAGAGACAGAATCAGCGATTCTGGCGCACGCCCGGCNATGTGNGCCAGCG
+
*+%#&!%%('+(&"(+%")!(+*$"'#((*")'&#$(&!(!)$'"&!$*'(!%(*")#"!)'$#+*))%%!%+%%"
@r2712
CACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGCGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGNGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGATACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGNCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCNGCAGCTCCTTGCCGAGATGGGATTTGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCNCATCATCGCTCGCCCNACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATNTAAGTAATAATCATGGTCCGGTTTGTTATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTNATATCCGCAATCTTCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCGGGTGCGGCAATCCGGAACGATACNGACGCCGGATCGCCCNCCCCACGCATTTACCGACCGG
+
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
@r2713
GCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACA
+
*7(?$6E6%>$/:F9#58HH'3D!"0,-7-G#B98'?E8BC%-)21G"CC2:/'9")1%
@r2714
CGATGCGGCAATCCGGAACGATACCGACGCCGGATCGCCNTCCCCACGCATTTACCGAC
+
06FD.'D(<9G*2>;7H@!:6,AB#@2<AG#$&0D$:,@':8,,D"C@5@*"8)D+#9)
@r2715
CAGTGAGCGAAGCCCGGCACGGACAAAATGCCTCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGNTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGNAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTNGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCANCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTNATTNCACGGACAAAAACAGAGAAAGGAAACGAGAGANGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTNAATAAAANCATTAAGTTATGACGAATAAGAACGGAAACGCCTTAAA
+
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
@r2716
NGGTAAACTCATNACCCCCAAGTCTGGCTATGCAGAAAACACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGANTTACCTTCAAGCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCANCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATNCTAACCGCT
+
"65F8'3,CH=@B!F0E>BDA+@"3-G6G6-05)F.9&+&/AF9GFE588>9"%A>:A(!+%,F3"F71*,D7-%*D+CDEG>D156"@</E",4D6C">*?,E0EG?0(8"7AE:*%",G!23'*9B:@@/>7F:B&B=#=.B,GE8/)'29/7H.73+#:B,3@4!6++0!0-@9.B,/D*!*83#@0A<!5H27A%C;C69H1#$,6D+%'/A"9C8G%=3E#&#;1B0%5B49B<&=)CD"H"49>CF;@2/.:DA.!*2'+,A16BA0D9.B*$3<F("C$=+A.7%-);?+0-
@r2717
CGATGGTCAGCGTGTCTCCACGCCGCANCTGCCGCACCTCCTCAGTCCGGACAAACAGGGACGGGCTGGAGCNTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCGTCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATATAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGNGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCAGCTGCCACACCGG
+
&5GH';)3,<!4;5>,.+B6+:=9C?F+-"3EAA:>.;/G*C;E'&57<@;D/6C>$27:@F"1H>'"E+0,15).#"8F.E?.)>6".B*(0);4B#06C8%5&36/:A%EGE%36''ABC:,F5+:23(=7!C&F</#BFCH50280GF%.G7$(1%/A5@&<<-!:$EE'.@$GC0:BE(4FH3<4'"F<4:!=!HG!16"$:E$??4*;=6!?&A+&2>C//$#)6B-F5E?1/#G9G+7H#>%8<=6$%6"&G/39CA)!7,?39%*)-E8BB,?BG.-.$54@*=*G;/<;E%/GE=&+A'>8!
@r2718
AACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATANTTCCGTTACGTTACATTCTTGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATNAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCATTAGCTGAAGNCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGG
+
-82E5%)H76%,1BCG@:1CD'2B/A&)&903(<@!/H98D8**%=."!!51(=*B95-6>G:5@>8>G0E2%E!"+=$(17H>&;8D:-DBB*,964:F+46A<)"1E'45B$5E4(-E151$-7-B?6C:<(16<!C$(),F&2%#;>B!0+'34':.@",@'(66&4,'>2=1(?'@10162+1.2H:29=>@G<7=&+D<>=F#)@/F38<474(0'(7G/4C4E8GHB/?=;##>@:/H=*!7!@+;@31077C!(*,1*,2'9#3H"2038#/,'1?97*?/FB9G==!:G,=66@=(=:)HA#>&G$E*C&#!.#-6$612>0F+B8H$4%3:-7%3"+/&$<A3B$<H")&8GG(AF4:==?#:;+'3,"E85?14*%@"1E<<B"A<+&<3E+$56@/#*!3;"$<H9?$5@">4:EC"(8/85#@5?.B<EC5-E2"A++1"9H)$=?D",5-G&0G50D7#0G#3*$64C
@r2719
GTAGGAATGTTTTCACTCAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTTAGGCCAACGTGCTCAAATCNTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGANGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCTGTGGATCTGATTCGTGTAANAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAGGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGNTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATAGCGTCCTGTTCGGAGGCAAGAACGCGGGATGTTCATTCATCATCACTTTTNATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGNTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACNCGGTCAAAAATCCGCAGGCCAGA
+
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
@r2720
CGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTNGCATCAGCTAACTCCATCGTGTATTTTGCATCGATCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCNTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGNTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCANTCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCANTGAAGCCCNGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCNTAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAANGCAGNTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCANGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTGCTANTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGNGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTAT
+
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
@r2721
TGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGNCCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTNTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCA
+
=@&#/4)0$(H<2+F68"0%5&5#/HG;4CF0;88="*:#9AE5(G@,)8=*>3'!2$!:"(C)&-)-!3/4"161.73(54/9B5,/<>*DA@-%EED>FA#C3=0:B*#3=E0C8'5=5/9'D4'<4?G875"4G":4$"(?AA"?;0.*+71$A/.40D3C>06&;451E8;H*@%BB':2BB13/
@r2722
CATGCTGCCACCTNCTGCTCTGCGGCTNTCTGTTTCAGGACTCCANGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTC
+
7B8!A'4",F$2#;4*(0C%,&B5=2+,0HB6G"2B07$0:?-)!:;D1*/8(D%+,.)A.0#)*5$19'">33HHAG='!11A?64:7#6)3A/%;-F@//%0,71F-EH,,"8*FH$C79=(#(7.>?E?,:BE8?2@?76$&@?1<52D&+-6!,#!2"7H5B+$*:0&9/GF
@r2723
GTGTCGGTCATTGGTATGACCATCACCGTGAACNGCGTTGCT
+
$E.2F+>&G5+!B)+0>73&'8FH%A3$B3)9,<3&!3.F(/
@r2724
CNCNGAACAGTGTGTAACAGTCCGTCCCACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGNAGACCAGCCACCACGGCAAATCANTCTGCACCTGCAGCCGCCGGTNGGCCTAACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGTCATACGGAAATAGCCTCCGGCTCGCCGGAGATATTCACGCAGGGGAAATATATTTCCCCCTCCNGCGTGCTNACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCCTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGACAAAGTTGCCGACGTTANTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATNCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGTCCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGNTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATNACCTCCTGCTCNGGATCGGCGTACCTGTTTCCGTTGACGAAGTTCNCCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCANATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTNAGCGTGGGGCGCGTACTGG
+
)#*$()"+&#'((')*''%!))&#%$!#''%%)'%*$&*$'*(!))'***!&)"#()+&+&!""!$$"!&'('(#""##))+(#"$'+&)!$%$')$'&"&'#)&)#+(*+(+#(#++*#&%)#%!+"&"*)+%!&)$!$'++#)*%!%'*!"%&)#)+!(%$()*"$)#'*%#!"!**+$&%$*"%'%$'%%+*''$)+#*!"!$"$!!&*$(()+##"%"+''"&*)"('$#+!'""!!###&($!")*'(%'%%"'#")+#+*'+)')*$'!**!*#!&*+!&%*$'&'%(+$&+%(*(#))+&"#$(!")*$$()#+'!"!&*(%&%$++"+*!$!#)$"#*#&*%&+*%"++'+()!&##'%%%!*+()!+!'%(&&!!&#(%*)*)!)%"&!$(($)&(%$("&)*"!%)*""+(")%'!'($))*!%%!'&+!")$+%&&(#)*&%"+*&)%)'"&$'$*)$$('&&)("$+*(*%!(!&*$#(($#$(%*$!+*!(&&#"'+&*!#%+)%(+''")'%%!!'"%+!'%&'+!#))"$'%*''#(!*%&+(&!*$(&&')"%*&)+(*$"'*%&""&$**))+'!**%*#%(#+#*"$"+(#'"("&(((&))*!$$*+($'!(%($&*#&!#$$$!%)!*!#'!%($)"+##*$$#+$*)"*&#*(!%&"$!$$&(%"'!$*!)%)#+&$!$%")$+!$'!'$++%$&)*+"*&('(&($+%%!%)!*'"((&!!!#%&(*+'"&&(+'(##$""!""!$&+(*"(*)#!('%#*('+$'*%#*#($)#$%&"##%(!+'!'&%)()+#&!*'#*()#"!")*("!'+%!('"&&&!+##'$%#&')*(%%'+!
@r2725
GTNANCANNNCCCGNNTGNTTCTGATTTNNGGAAANCTTCNNNNNCGTCTATTNTGAGGGCGATTTTTCATCTGTGAGGATATGAAAAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATNAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTNAAATACATATGGTGTTGTGTNTGAGTTCGACTGGAATG
+
#*#'%%%&#$!)***$$"")$)(%*%''$!(($%%!#)*(!&"#%%!)*"%*%+"!*$)"*(+''!%"#++"$(+&(#*(*&&"$(**'%"!!*($#*"+'!+(+*)'%!&(&()'(#)(!&*!++'''!$*&!*$)&!"*('''#%!(*!*')"&%#!%%"!*')'""'#!#*)%(+)!%""#+$#)(&)%#')&%'((&+&&(#%&!%("%#&%+)"%#*&)+%*!(#&%&+'+'!+'"'))'*"!*&'$+""!#$'")!%*&#"&'*"'"(!"))(&+!&"""+&$((&*#+'%'%%&+($$(%#'$#+!%"#"(&%*'!!+%%++$)#+)$&&*+!)'
@r2726
GTGTGANCCAACNTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCTGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGA
+
!)%""&"#(&$%%+)&+'!&'%*")'%('!!&%""*%+&*$$)(*#(#)")!)%!+$!&(%&#!$#%#!*$$%(*"++%#(&%&&"#&++!($"!+!'(#+!&&+"%(##))&$)%+)#!%%(*')$%)!+"*
@r2727
GTNCCGCCCGGCAATCNGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTTCCCGGATGGCTTCAGCCNCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTNGCTCAGTTGTTCAGGAATTTGGTGCAGCANCTCGNCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCATCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCNACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGNAACAGTCCGCCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATTAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGGCAGGGCAGACAACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCANGCAGGGGAAATATCTTTCCCCCTCCGGCGNGTTTACCNCGAAGCCGCACGACTCCGCTGGCGCACATCGCCGG
+
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
@r2728
AGCATGTCTGGAATGGTTTTTACTNAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTAGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTNCGACGCGATACGGAACGAGANTTCCGCTTTTGN
+
0B-*@F:&+9-G01HA(A,!1@=",5D:=/AE!'=#$7.<"@&.$A&?H,&799C%<$DH?4%$86#?>:47C6E9-62/1-E7$FH5!"8-8+H->8C!B0:%;:),)2AB&<AD,A3?'*40+&+,H&<G,99-;G)?=:)G="H93/F)01'+-C:AGF;8.(#>34")69'#H<.;C:F&F5:*A$)'",-#/?&G5E<35F<(;D?B,5A)
@r2729
GCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAG
+
E0$)81B(A&$H1?F12$2C3&+4!D8'"+5!@4.='9+;..>B%7-
@r2730
TTTACCTTCGGTGTACAGGCACTGGTNGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTNCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCNACGTGAAACAGTGCTNCCCGAACACGGCACTGGTCGGNGTGCAGGTGGNCTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTAATCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGNGGTATCTGGGACGGAACGTTNAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGGNATGCGGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGGGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCAT
+
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
@r2731
AGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAG
+
&=16119%<3>)&1@G4+@.F='5,)9@B>.;94-&FGE,3=+/;*#H(2F>B$>-'>3$CAC?"C9.71'&#6F,>D1<G!G:(G%H9'3$3;=,*5:,/;49-A;1/4.7>&FF&1+,G02'E''?;H!DC(8+>G139;="E9!7F
@r2732
GAATCCATCGCTGACTGCGTATCCAGCTCANTCTCAATGGTGGCGGCATATATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCC
+
!(%+*'$&*&$)!"#"%(+**#!"#*#(!((*(+"#(!)*!#%!&('(+$&"%!'**%&$'*%#%$#'*$("''!#!(&'*+*#$)$!'&&'&#"+"(#'$($$%)&$)"+%'"#%%++$)(''&"'($('!%'*$($"*"%(%%'(()&$*%%*++($#*'$+'#'""&)%!'*("$+&&%""$#+$!$"'()#(%%&%+##$)&*)#%**(%%"$#"&
@r2733
CAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTG
+
6C+-<A$(%D'*9>&=F!"#A'2/9898)7)>,"D7(/60H46AE,).6'6'#3!='6)>6?H5-#'<GBC'8D+)'>=*$40?/?-5:H%H$09#*#B6):FC655!3"8)@.(B7>-5H#>454,)-H*<624CGE
@r2734
CGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCGCNGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCGTTNATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGNATGGGTCAGCNTATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCGG
+
-E=:,227<G@E2(=;-/*@8-60/-(<"63+%(9&34G$.5398.3B%-FFD"=*G9.03'$E+'0%54C+H63*G:>28&.H(-*+B;HB23'/B:"0'#49#</1)+0->E<';-0.6:E3*3?;:0)BH.,7&FHDB!='31(CF$29!.,G'17"B8*E!:)797-<.#F349+@2/*.')%?"!9-3,/*)(:4*4?6+4.$1*:4B$8144-,=FF-C1)4H!+;F*$04/7,E6?*BH"4'76,1&@F!!;'1B@D/H*..B=-EB>(%A.<%62E@.?);<D3>)6155,3#=<0)
@r2735
CTTANCNNTGGNACNCAAATNNAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGT
+
&$$)!*$&&(!!)!)"''('*"$++!%'"+""'$#)(*')")"%$(!#"&&%)))&"#&&(!&)&#*$!&$"+(!*+'$!!*(&*('*+#)+$#'&&#'+%$"'!"+&)')$!!+)%)"("&*(##)*%)(%%+'''%!$$"#'*%&&##)$*$&+$#)(*#"#((+%%*%!&#&($*$'+&&&)*")%!%+%*)!&(%)$$&"%(%$&"&+*(!%#$"&)((%!#)%"("*'!#*$"&#!'))&($$)
@r2736
GGAGTNNATGNCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGNATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAG
+
&*#&'"#%()%((+!%#"')+"(*(+!)")#$&#!"&**()('(#&$!#!&&*&"!'+!''!#(+()*!!(%($%'&&"**&*+$&"#)&*!)($+++**%!$$&)%'&)*!()+%''("%%%+%*!*'&#*!+)%+%$!%%)+"!&!*(#+#(*#)+"$("*$'$!#"*()%$&!$&#!!(!'+(#$')#')#*%
@r2737
CGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGNCAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCNGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCTTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCNCGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTG
+
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
@r2738
ANGNNCNNCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGACTGGTCGGCGGAANGGTGGTCCGGCGTAAGGTTNACGCCCGTTTTCTGGATGCG
+
#!$"*'&+*$%"$'+%&$*&$"+'&%!&'&$+&&((#)$*")&&*"#($$"*#$))'!&#("*&&$%&(*$(&'&$$&+$('+)#"*#&!!#)#&)#+*)()#"&%"#++&#)*+('))+%!%
@r2739
GATTAGCAGTTATGGTGATCAGTCAACCANCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTT
+
/%)49,BD")A>3A<37?9D%:=1B/)9/)FH>7*5@>#<7.:BA,8*:2)<&5'(,,@G-C./=G0?6+=/$;6()%2:8=GB$<:D)1<)%;513G#6'87&+AFB:!5A+
@r2740
CCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTNAACTAAAACGTCACAACG
+
E95(+C@5+0)'@<8C$H)G,?(.H;?7>5597AF)#0-CF1"E'!'6<F;B1"H+';HG22@??/*<1#>8C%4/5*G33(14*9-+*867"79G-@/4+.C?3*?%(>&84.4,1GFB,
@r2741
TAACCCGCAGACGNGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCNGTCAGTGCCGGACGGCTTTGGCGGCAGGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGANGTGGACCTATAACCGCNGTAATGTTGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATN
+
AD$4DFH;1),GC.B<*$',7C;?E0',&'?4G.G'9.E1$4D.15>"7&)+62;H!9"(GD697957#$7,$#"<).H#5663,H!41/HH'A=1-H=:H5=G9-.H5H-47H+GEB+?@6C!>E7&&<9+;@</=;.?6$E+H>3<6:H=<%F,$=;$888E!1=H7*-%$#1'G<"E"!=6=*GB$)+5F%0>--%;&A(<>:7#(E<1'',="HB-4:D2&04(;D5E/*9EB'$6EB/1%;-9#B7DDA018;2&GBG=7(.F+H59CDB$+,9F(8B:#3D#=*0*3"=C72>%BB'8/>EB7#!<=)E!CB04))0G#E)AC19"9!BG'H=-!*%)()&==93@1$-A%!<D9*#%=?E7D32G;40@7<;H.E'"G&)-C)G,?+>F$2&?B#.1D%*!?FH%*:-;B42"5C>,BA#<EB=B7")4'4*F1!4+5!$%=(&5F=+%@2$@>*$1CD
@r2742
GCNCCTNCACAAGCAATATCAACNACGATGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCNCTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGNGAGTGATTTCCGTCTTACGATAANCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGC
+
%#!'*''*()+$"'&+"$)!#))+*%!*"!%#)**!*#$)"&#&+###+(#(+)#(("(')$'")+')&#&#)'!$'+)($%%$#'&!)&""*"**##)(%+$$!"(!#&*')&$%%*%$"!!"'#+)(+**!+(%#)&#&#(#+%$+'!)($+&")*"'()*(&#$'$$'&%&"$$#+*$")('(+%&($(&'%#)*%+$&%'#+!"+'#'#!!%(%"#(()'"&*+&%!)$%++)'())')!((#)#+'')*(&+&+%'((!#!"
@r2743
TAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATNATGACTCCTGTTGATAGATCCAGTNATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTNCCGCCGNGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGNGAACTTTGGAATCCAGTCC
+
H6%'06$7!G-"B,#;&<0*/9#6*6=-;$3-+'9$0'*2E?"8?AA;,!CG$B?;$B!3;,DF-.;(5<<9#C%+H83D4F!<.5):E)H6/*$8=68BGE=DA+*#1)(/?=$(7,G'G%%',6A#-,3C2#A"3,4G+B!&:?-43;A82?DHB+@GEC'D':.B%C*@E6=1??)?=A":G3"F2%EA(E&658''9AG7"/2:"#0:,B,F8+AE-!)3><G('B-7FE?!<7G-G@4>7"-A*2%%087*0'.14$9>:$D:604>:(CE,$
@r2744
GGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTNTTATCCGTGGAAATCAAACGTGCACCACTNGCTGGTTACCAACCTGTATCAGAACATNCGGGCCAATGCGNTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGNGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAANCAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTTTTCATTACCTTGGGACGCATAATAGCTTCTGTGCGNCGGACGTTGCCGCGCTAACAGGCGCAACAGNAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACC
+
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
@r2745
GAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCA
+
4+?9B40@-:E*A'#3F:+H-#=E9);:@?:G209.,/:"7&3'G1;:47,%!*7)&@1'B;1E"A+3>!F51"%F/-=,1H.;8C9$G(-&.(A26).<>:>B(B4$03G6!9AC#):+6#B=CG+9<(7:2$15E#(/=09(F&GH
@r2746
GGGCAGACAGGACTGCGCGGGCATTCAANGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCNGATACCGCGCAGGANATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCANACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACNCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAG
+
)6:1%>5%H/G)*$=B)%-<32/9+D*CE!"7$.=09-?#!(,5<<0'=3+/GDEB;98=3H8E3C1%BH*,)8B9>,17H-@/918?",;B;*'.%DD<7G4AB"&=G$,=>A3-*:*;@'A"/F68*GC!$3/053(7H<</"0@6"$E+2A?,<;$5GB.D?478B.+#A(2?GF2FC2742@"1B880(!>,ADEC6<??!+)7%,@,82&2E/&C*#E)B!B&AA#&H".4"B<B/DD0=GG%!@>$C#D#2>C8,%!*.4BG<E<B73/=+B02G2;C"HD?G1+:H%A"D@?70EB@;E?D2DDFF9C),'/2)>''.9)1+/8H>$H(11*>G:+;7+%-=A8/*A?54B8>;3,(?8(2=5+(%+3G%/>&.AHA6C"+8$;2H
@r2747
CCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTCGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGNCCACTTCATTTCGGATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCNGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGNCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTNTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAAT
+
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
@r2748
CTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCT
+
(9G*HB0<DE'&96?/:1>$>77#!H1+(E;$9A(*'?)#AG38A8&.93>69".1(>-C+FA);C*AD!58A=7A=BC%'8.30(9A17?@HA%'73"+;&5-?'80#78."D7>#GH''D1+/-(*9().A=?5A=7#!.)!0&C7FB9(@F45CBH%CGC')-E+E'40G0'>9,'H2>,8:"F.@%)'="2)%6C4>%$F>,D/4%3
@r2749
TCAGCNTGATTTCCACACCCTGTTTCTCCGCTGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGT
+
/:AEH%"B-'D(16">H$F%'161#*-;GA/=B<(>-3=F!4#0?%;-FEA<,$G879&31502;(BEHH,(<@56#!7%(F$E-)"%<,:==+G@%-;H,7:!$"GBB(E7!27(:;23*GH-95?8D4.=G6=($"+'3
@r2750
GAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCG
+
81>.!B7%6.3<=<H7>G3'$("-5>3.8:#G8:H#73@A>3$,"H1/@B!B@3,#>
@r2751
CAACCGGATGCTGTTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCCGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGNTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGAGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCANACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTNTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCNACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACNCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCNGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTG
+
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
@r2752
CCGACGTTATTGCGGAACTTAAAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACGCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCNGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTNACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGNCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTCCAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTNGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCT
+
7/G$;5.,$;+-(;+F=B.+47<2.)&<=")56-2C#$DH?F(B2/#D>A,"B<16)93?+1>026A/3$/'3A1(!8GH?:9&>8D/80@-)#@45!#-:A/*#'.1B023B8"$<"H*9@":F=+%(867>--36,+9<EF6,=5<#35D@(.A=!>&+33#,)BD%<DF4#G/$?1'9@A->/*1"%;,!A71%:+C)G;(4#!B8<A$03B-!64%H59/-)<4;/GD<!E9*<@..*4=&H*-*;-;98(C5><.*F@;A36&-.)4B,!EH>G)4(&B3:@;"/5/>,04-,?#FDB>;&8/C1:-C5H7&/(!+/&=,&4&-<5G*-$E4.A9E8:#-;.%;"&8>E(H(BH=8"4%6'@E,D2)<GC1@6,<3$2B<9!*G)2*+3'/)>8G@;BC8D(:3==<<,*1$16H>=D%'!3#6G:'?-54C.=;-503'1A"D&CB44).0=)=&1%?=152A&8&E@&$"37'@@'HEG"<<-2B4;(63"96<F<E8""-?6/(%(=1G'D2&9',!<;FG;3+B,E*/H61>G(<14"@"8G()A6@##",*+;C,('+C;C66..C$G'(GG//=("':@1D-%>6B)$
@r2753
CAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACGTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTA
+
0G3!A!"@AE%93=/9AD.90""<'5/?>6,441BC3$D@-7C>C2GD-32$D4E18(?7+)G"@"=7>-H2,'+:D>8A5'77ED?!"C5DC3H00=/'3D&;?=&/=+D&3F-<;7<"=:G3
@r2754
CTCCTCCCAGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGATGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGANACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGG
+
%.!HCBC0-:5@D<*(2!@747(6'3?=95>-G2*:,DB;<7B5+7,'?5&'.&697B)AC:0#12:=6<H@=B8/C$<GH5,F-$8),1*1D<:$+*&CH5;-+G(=+B8A.0E<*<5%&EH-)F;%D).?G+D'==B1G-2F76<-))@"9.%9>:>!A3)F"H41/G+!'H0!2%&D@+%7,96!.-F(13(@7:5?><!DD+-?G/!)*9"=9:%-H!HH:FB-.:4$48/=+H3'70406'+G.$'8#5<3FCG'3A<4BA?B)>G&E2#H,1E%(9?-8581GC)5)#=3(+F#&;@8>6,*:F3/&GH0<5--=>G&%+>?>%8,+"2E,HD5>
@r2755
TTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATANGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCACCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAG
+
241-'96'(B1/0;?G>C2"..=#&73/4#0:3:(E6"#'4,AF2@@'9C7H%87-FH4?.0@A;A>7<;9E%@E!:-$3<BD&.$@C!H%*(-4E<!-$E29+2C'2A*"2?);@-,>.;@B')',%57;$DE<2:49.,*&('&>GE?0"H=@B"C5A6D!<79HAD6/'G<:.2DC6005=;%D=4:0%"&#-!$AG222-=41'&(G=(*0F'=+-6?=&.93F!B'+(*$,*=$BB.209>9,$>DG9<,H&@/>6D0HGF7)7,*?;;<DEB6$$2$#?#/;=#7$C3G=*/F#78E<9:(<H#>G#284.(G=,3/H;E0(<'C))>,38"(07C&G=4*-5+2A$;.@?#HB'+(9+';')'F8$;!74G
@r2756
ACGCATACTTTCGTNGCGANAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCA
+
*..A82C*++B0>=</2-%/67@,$%4,8%,5$26(D34)C7DG)2D?D9AH?4#:A8!+H@=/AG/-"G'>-.&ED08G>/G500H#*/*48"E1#:-?%AF3B+66(E;,:G6?996@0$H@<.;$5B2:B4(;C/:E;/#B656$7%<,25')@$A"/F+E('6(5;>)37B8<+"0#'
@r2757
GAAGCGGCGCAATATGCTCACTGGCTACCTGCNTCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATGCCCCTCCCGGCGATAACCAGGTAAAATTNTCCGGTAACGGACCGAGTTCAGAACTAAATAACGCGTCGCCNGAAGCCNCGTCATANACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGNTGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCNGGCAGACCGGTATGAGGCGGNATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCNTTCTGAATGCCATTATGCAAGCCTCACNATATAGTTAAATGNAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGNACCAATACTGAAAGAACGGGCATGAGCACCGATANCAACCNGATNCTGGTGCGCACCAATACCAACTGTANGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACT
+
:HHC-7E"7-59<@3,7;-$2(;1+H$0B+D"1B)(0(-/F&:5%-FB>1<A1&6#$AG;C@4C,"A!HF-&!H"A0;-B123+/78>%*-!B?ED*%#7/:D3"3AG>EEG((+@-3*+7#?0.8/D'GC@?5D5&*F:=681%G;:94);08:5)7/@;7(.!/G(4#$'=?'>?H"8;GED<@;*66*E;*9:?2,5:@,/4G@%E14$<*?6'GA=?">FD?=3E6=0@+)A".H7E10C!((,*$!F+>.G:%A5>F>$+D*,)9675FFG+*C&!<B(/.C,B"8//;"(<'$>>FG6C@)4"+0.H-"C3?!.9$=5A*7!<G-8'FEE5.839,)365)">"C.0<BE-&.=#='-H@&G91)8!@*?)7(5#$,H"6-457FH70<4A?5$0!'&(H/DC96?.1<$D')G6D1!'*E';21';&896>EE36B!$?)#@;)$)8$0C9&9/5+'7,+=5/F6>'&749;1A<BB%5<)%'=/#20>2,>D9G-B:2$!?5;#%;/!:"4"62=<</%+C?,)1CEH5?(?B1599"-(%.8"8BF5B('>A?8%G717(,F;.B2>7%/5=70'+;%2/?)-#'9%,7+H<3E5#F0%!7"*7$(0AC*1/'?0<.>3/C'1@2>#:40</<@$9B?C9@$:$+*3?,*HC3B>3C$><?-632<";7,0A5%>$+0A'-'::.0!G/:@+*'E!!C2'"):/*&9+7C39'/-G07(=6C/2-C!;.$$)819?0>&-6)+>2#04"#%(9=??A
@r2758
CGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTNTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGNTGACTCTNCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCNTTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCAGTTCACGTTGATGGTCTNACCAATGACCGACACGGTGGCTTTTGTNTTACCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCT
+
-"1)!B(G&8).>(/,5?HD-,-H+!C76+,A4&9"@D#53=;@'B6(H4??0"&&6?E%EE/;26D26&AB.>40184A86>%"AF!!)9HG*;E-H=6CB(1%601'8>@C.'6,)E314FE-EHE44);D*6H46&0E50*EH=H'003'E1<1,+,.?18233%#.(;'!7:$./FB#'0?:::':&.;>072;5"4.#68=6F&(:,*AH2)?#3$BF%HB$+2@&"=7G57>:3"9/2<2<"B5E$$%*)=,!))59C!)@-=@=E&1(.-?49H?,H//H'>%;1.G)E"4>"GB5)!=1;/*=!)A5$#6BA)&G0!7+-6*(A3/A9:<8B((@6#139'8+&B@%(>7><(8"BH')*,133*AE:;G/+%7H"GE;*0B.$+B7F-;5,AB:)?@7#E)1.6&$84,%?!+01$F51%",64C</4;F>&?G,
@r2759
CTGCAATATATTTTTTCAGGTNAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCNGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCNGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAACAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGAC
+
8GE9&6&H-,651.$=44CA$;2H!A+6.7;,H&E@C;@G5:B,+CD-!55!3@!=B35#*;(7>5-@.*E/97F=>7?-"F#%*:;">!A,;789%2D7+/&1>2=8".$H@#>3-$(=B(68B56'<6H1?'/5(&,@@>HF=+F8H6?**-@$G?#<A&#C+!@)9:/&5-""!A@A;<#;*2E<$F.>D/D-71<A>EE140A:)!<!8*":!'AF>)C)9<#F$3"(?B01?:(:G2/633'=-6$5G:44&F)H*:8.G*7F@+A#=><,(-"?=;B@"'D(!F&2,8%*'&D$$$#)H/H$-@9>E34C?D9("4E-"FD+5!2$3!(/-@2B==E91B&90F!$+!H!#'0!@//?14#+=A9/H8%31
@r2760
CANCAAGCTNTNNNTCTANNNCNGNGNNTNNACNCNGCNNTCNGNNNACGNNTNCTGGCNNNGNAGCANTTNANTGAGTTNTCNNNTNAGNTNAACTANTGCGNCNACCCNATCNGGAAANNCNNGTNAATNNAANCNTTTCTNCAACANCNGANACACTGNNGNNANNNNAAANTGGNNNCNNAGATANNNTANAAAGNNANNNNNGTANNTNGNNANANNNANNCTTNTCAGNNNNNCANNNNNNCNNNAGNANNGTNCGANGNAANCCAGNGTATNNNNNTAGNTAGGTANTCNGNTCGTANAT
+
"$!$!"$#$##"!$#"$"!##$!"""$!#!"$$#$$"#"$!$$$$##!$#$!$"!!#"##"#$"$!$##"$#"!#$$$$$$!#"###$#"!$"$$$!!!$!$"#!#$$!"#$$"#$!#$$$"$#$$##$$$$!!##"!"$"#""##"##!!$#!$##""$$##$#"#""$##$#""###$$$"!"!###!"$$!!$"!$$"!!!!"!#!$"##"$#!##!#!"!$$""$!$$$$$!#"#"#!!!""$$"!!!##!!#"##$!"$#!""""#$$""$##$!#""#$#"$$$#"###"##$#""!""$#
@r2761
TAAGGGNCGTAATTTTCTATCTTTCATCATATTCTANATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCCAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTANCAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCT
+
#!$($+)$$!*+#'%+)*)%#)(((*$*#$"+'$&+*+('$)*''*(&++)+"!(#"*$$)"+#'()*)$$+)"$'&)*&%')*"'+"#*"%*#)')+#+%($+*'&%!"##&"#('(''(&'$"#)&%%)!"!$))**%$#!'*""('")#&$%+"%(+&'!(++!)")$($%''&$#''!"")$$)($&'+)!"(++$'(")$&%%**("*!$))'("+*!'&#)"&"("%&$&(+)(%!
@r2762
AAAGGCGGCGAGCGCGGCNTTTCCGCGCCAGCGTGAAAGCAGTG
+
0/F#EC<$:29&)D/.B0G:?DEGEC4%12B>)*0@4/!E3></
@r2763
GGCCATTTTTAAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTNCCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTNACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACANATCACAACGTGCGTGGAGG
+
#+#!!*))!)&#+#)&'%&*("''"$()))!*$*&*!!"#+#%$(*&!'")"#'(*&)"!!*#"*%$%)"*!!#(('!#&##!)$!!%!(!*&)+***$&!(*%&%*%%''*))&$+%'))$(&)*!$#&!(%(!$%(+%##"))#(+)('**&(&'"'+!*$"%'&)")((#()*!&")($'!!')&##*(&"#"%%&(!*''))**+$)&$!+'$%)&##%%#"()+()"##"($)&&)$"&%$")&$$'%+($!'((*)$(($
@r2764
AAGNGTCCTCCGGCGCANAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGNCGAAAACGTCAGNAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGACACTTCAGCACGNGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCCCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGA
+
@F>4(4.4673(?<";A+2'(-.AG*"(G<F)-8?-(1A4'/00?<<".$&2014*!=)AG1=417,80$9D!7?+-9?C..E12*$*!1,51"$@C4*"0$E;592'"@82>?)@B*3?=14B6E?4"*6*4C%5(,EAA57&""7AH<!9.B+A4+CAC!!;8"/60#3:CG'9C+("6'2C:+0G3=;%+>1-F%D)@C79$)>)<0:F<+0G%4!B)39C.+,0.0:)1</3;'AA.-*A01)#$:8-&6(H)G+A*9=BBA27F72B4HG>8>*GEC<=G,=#*?E-13,H:::CC>D4=!<3,"1%G.A1H%"6.(#?.D+F!-&@0C1/!-7<7F$,HBG/E59!/,@C.5.=EH6$743,12>F<*48$1,&)&E28?=).5CD%:.<7?A/-D5&E"'?H"9EG5267%(9-A$5?C,10&,2G@2<53
@r2765
ACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAACGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGC
+
90+E#;.(&HF74+;8C&%8'+/6=3)0=2*1;;+"!@'/)>3H9+D/B!>,D'$858AC<169&0D8D)*;7F!0!!)C.0C.55*=#:>)BC!*)<'@&&'$(:A3GA3>@.B>8069+E;+D@97:B<<(#(&"*"<>24%-2*DB>C%BE:3$B18)>C</A8#!C!'707?0.$H)9;0.:$3#D9+,GC.::FD08,<GC1"F55-7"BEEC;?D?&8E#57"/">?%"922(3(0/C<>'&D*>#*=A+)A,3>88>9,,$07,=!7*AA@&E#1A*;$)</5E)DG:)+C*F72#2*3.<:C.5@?@3?=$,9$-:$7?95
@r2766
CTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTCTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCNAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAATGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGNGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCNTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGT
+
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
@r2767
TAGGCATCACCGAAAATTCAGGATAATGNGCANTAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAG
+
F'C.!H"#$E#25=4?F?:>.>FG;$6$:$95=1(3H*@!(BD!H3@,:1>=E%6.37$;8>=F?2)*"476(5.*4A,,2E+>*$4@'/&8%=,,,')+=0G4)A!C;0:GH*@#07@23799,:-BC(#>"9G+ECHD/7)B;$C96F,#$80"(97*B?F@@B)!>&?)%D(.842--?6G?=!(96+78A0&.!+00%2EE,($;21(F)H5F4G-0/2CH;A4>#(G-(4)97$",@8)DF==CC>A>E=FBC1&8)$!B,$AC80!&',?1D41&F@"*<C?=6/,D,0*%BH,=!<(5?8"425/@7'#=-?-7D8D;F65;'@:509'G@0%>;-$E6B0AE%A=+<?A@B?@7CE;H!
@r2768
NTCNTGANCGCCNNGATNTGNGCNCNTGGNNGATCANNGNNAANNNTCCACNTGAGCNNNCTGNTTANT
+
!"!"$#!$#!$"#$!#$!#"$#!"#"#$#$!!#$$$"$$#"$"!!"!"#$$""$"!$!!"#$#$#""!!
@r2769
GAGCAATCTATGGTTTTGTGCGCAGCCCNTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGA
+
.%!)108(0;1)A)05<?((/D2C02/'C&+&D4F,A65@03*$4'5@$7;)-!'@)>B#G#,"*791A:-$;4=4F.G7568G0*.63"E9
@r2770
NATGCAGAAAGCGGCAGGGCTTGCNGGAGGTGTCCGCTTTGGCCCGGACGGGAATGCAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTAATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGNAAAAAACAGCGGCAGTCTTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTNCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTACGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGNCGGNCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTTCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTG
+
#?0==<962DE84?=$/=*>&A5E*'3<&4(<4;4E4'&GD33GB120%@)$D/993?E>(+++=4.(2)6*D<9D()),2&B:6C7*F*>$:@'H0#;$*E+*,;C9/69@77A51@B/6*B:/2F>D31'(6'H2790%5>?%1??D>>=*2@-#36A:D?"D&%&5CBFE=C-)3A9:%7+8=$?CE1D2,:@G)-/(@>@:/711/3357)1+6B)4;G5C'G;70A=(7B:/*,15CA&'*;,2D!;/HD9A"'&AE;F5)%;E.?>&?-();!/&&G)/4(9#)B2%5*61=:>BA93'2:.#6+%?<@;4.H9CH8)3B0FFH%?H!>(H(&H1&<@'3A+("0DD2;;0,/20/HC7=,3<$3A15F3$'CB./<;A2$'+7##+468:,HBCB@3/9C-,/?D1CD.1,<BD0=2&E3%*,%43D"1,?E:A28,B:8>3@,H7$D3"/,+"C('0?HB?3->F0&<<4G@E7!.70'F:*7C
@r2771
CTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATNTGGACAGCGTACANCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGANGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGAC
+
>/'+:2$",D'=6,F6"(>?H,@$13D'.=<0;D7>;H>".$#'%(<:F-.046*:9DCE<'G-<9?,-:'3=?"4B.*A4"**$,>07'D*G;0A)0;<:76#51='$1%1@D$D>51E+?DDAA-3!>EC)&.%E(+-3%F*=9#.--4=9@*49@+(.?@C;,3(EFB6D)A8+2>%'7E91FA-73G')#!F#@H-@<-F<=DH/(/.#F)#40@++DB&)!AH64<>E6(FE$&.2-1@$??+.D5B2,#&CGG)@AC'2=8D:>1*@$7G#>4"@A%-0)#;"#BE+H)@!%:3/7E.-4@*A1A7'6-E,44.(F=:C8G48$F*>:9#*,G;#+)?76H,+%
@r2772
ATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTNATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGAAAGAACAGTAACATTTACTATTCAAAAAAACAAAAACCAGATTGTAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATNGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGATGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCNTATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATNAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCANACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTTCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCANCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATNTAAGTAACTAGATAAGAGGAATCGATTTTCCNTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCGAGCACTGTAAGTTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTT
+
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
@r2773
TCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCCGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTNCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGNTAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGC
+
E/A@"$+G..("1)&+?<F>#5(!'#D5()/H:+DG%3-1%-8FFA8:@=9)8>96#51"92,G*/G?F>A9/6=&1A7($-?6F5"48<#C(8@--8,4-0/(G?%1'%)&&G8E)8)7",-@:CF%3?=8G5#'D@,.9.GBB1BE4E96"4,.#&A@"@"0+F290'0H>@>A.8!)-4H0/(!<,(*%>.!@$')8A.#3<"DH$3A.&D)A/4="982;=F9)9)C*2,7F6-14@,G#08#*E>!6G@."E<'7%H)H''?@/.=01G#F7((+(
@r2774
CATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTNCACACCCTGCTTGCTGAGGTTTGCACCGTTGTGNCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGTCTGTTNGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTNANGCAGTGACGACAACGGCCTTGAACTNAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCNCGGTGGTTNCGAGGCCATAAAGTCAGCTTACATGGCCCAGCTGCAGTACAGCATGTGGGTGACGCGAAAAAATGNCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGNTAGGCGCAATCACT
+
*#&++'()"+()'#""%#'"('*#"))%*%$'%$!('*"#"')&(#('&)+")#$'!*&!))!(($&+$!"))&)%&"&*"("!*'*!(*'##+%%#!+(%"++)(%$)!%#'#$&%$+#'%+(()')%&)%&*!#"&+!#))*"!*'&(&&)&)$$'**#$($$*%#%)#$*')"(*'$&%%""($&'$'$"!%''$&$()#"(#$+*!)#)%#&&+)%)')"%*')$)##&&(&$*+**&*(%&""#&&)+#++%$*#$*")++#*#!##$&+%#)(&%)$*++)$$#%$+'(!#)*$#'*%(&(&!&#!'($+$+*)*!+%&$$!('++$'$$!'")&'+(%$$("%!))*'""$"%!"%)+("!))"''#&%%""*')%&'+"+%()#)("'"*!")!$&$)("(((")%+%)(*+*!+)&$+)!&(&'$+(+')$%)#)$(*!++#"%*(&$+)$!++&$)%+($+!!&"*&%$)'$(("#!!*(#%&+')+"%(*""&"%&!+*$%$%)#")"&"*+)%&')+)#&'!$&)*%!#$!$#))'"#%+'"&(%&(*$)+)()(+$*!+!%%(%'#)"%+(''+''"!$!+"+#!%%#%%'&"(!%'+*$%%#!(!("#+%"*(**!%(+""*)*+"*&&)"!%'&#(&'($%&"$%)))&+&#!%#$*)"!)('%**$%&+*!)!)!+)*%#!)(!$*"
@r2775
ACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCNTCTAAAACTTAGTAGTATTGAACTTAANGGGGCATCGTATTGTAGTTTTNCATATTTAGCTNTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCA
+
5"?E9.57HF-:<-%&./DHG&#)73#02D3+"GE./>;$@5B#F7D:A,+$;H"CB$4D5!66-(=A42"!%A)!:E6)'=H;D$?!12;9(GED=$>>"28160@04GD'B6E=$%<<B:.3;/6EC-:<<56G%B()?,H4=:?!/:5-5+',$<>"+F(2/D320H0"$HDA!&=A#-?5!?6$HB0?&F&02"<53HF,,1(,FD>&+07=8=C)2/354C8F.'0A9.5))?G(/AF.F%=H/5(;),$%%>#,75!GHD>:G878*,D(A-H3#?9
@r2776
TGGGATATCCGGTGGCTAAGNCGTCGTGCGAGGAAAACAAGGTGATTGACNAACATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGACCGAATAGCTCGATGC
+
D148#?!DF?'7(%'6;?GH&4B+',H;:#DD1!''7-@"!E36-2(<(,0.+%#*$D$%+(?.+37*B@9DC4DC561=;2'6%+:/0@&"$C+C1!:H&;H8=")E*=EH(G!/G<0/50,:)",*#=<:$5>0-4/90(<!$9EEG&/F#?37!2-A@6%B;:544H1#D#$%(.0D#>(0.$.9
@r2777
NNTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCG
+
#!3*2/4-!<*(9HH&B@5*EBDB9B=2-(3:.)/,*CG-D7><7,8,9F"?3-5#,?92B%"A8B:/5G#5%62,!0=2&.%4
@r2778
CCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATNTGAAACAGCAGCNGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGNGGCGGGGAGTGCGTNAAC
+
$&+&)#+!#%!))$%($)''''&"+&!+%&#)+)%(+))$"&&&%'##''&&"(!!*#%"#%(!")!$*'''*(*%(")#$$"$""(&'($'!"()**++!%$+(#*!'"#)!&"&'')"#'!&%&$!)!#%($('"##))&&""%*+%)'$!!'$)%)$#++*&!$#(#+((&%#'&$!+$
@r2779
CGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAAGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAANACTGCAAATACCTTCCAACGAAACG
+
D'>&'A/HF25D4'G)HC5D'+AD")13!=33@A0+>6E?1#D8E<<)5'5*86$G$!=5-;?&@H&.C$/40G0;)6BG9C?,5=&/CH,/<?E0+8E!<4@7"H:?$'92E7.<6FG4=7'G)=6;+B3(6DC5%)(D($1-(3"/5GA>059B7HE/%(-@(C
@r2780
CAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTNGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATNTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCTTCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTNTATGCGCGCACGAAAAGCATCAGGTNTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATNATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGT
+
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
@r2781
ACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAACCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCANGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGACCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAACCGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGACCGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATAGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTG
+
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
@r2782
GGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTANTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTNTANATGTTAAATTCTCAAGA
+
-0+-C$*,#,#-9DB01B$?E>5CC-B(3FB>,+F,*2GC4=;#8#+%4>/.:4#3/)!-&7$0;G3@6+4'&&)'6!*$9AA+(DB=40A7#3(,1B+86</G*?B7#*6,$0AE!4(&@>>*G6$%F!!7)&*B4F7!E"C>0./A9<73.'$C(<;@85B@24D+6A;B+*5C1=@:!:?+(D<C6FCA;"#4%H,
@r2783
GCCGCACCTCATCAGTCCGGACAAACAGGGACGGGGTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCNCCTGACTGCTCACCGGATGTAATGGTGGCTGACGTNCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGNCAGCACAAACGC
+
EC1,/;/$=41=!F:+(6=8=4B":HED),&&;?2BB90%B@0)+2HG&1/,%CDD.<#;>5'G*'@1*$DG+&,G?)A),9<4;'EE;<<@=298(.<''37:A0CD2B96FG?H,5D/;20!.:/=+-85BEH<##D=/(G*.%.0F2C8;6*E44G(-A<!'#=%A<7==$3#:2E<;41-%,&D&3';"<-3B*H9;)CCF=5E@56&#)B6$/4*/(B<4H<)-:8=,6@+<'%::.E$6A716!@6.%C.9'FB:2$%B%,'!<3.H/"=$-4?G53EDF6*(+($$*)D)=*&*"67?(.HE+59-#==E
@r2784
AGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCG
+
F'G:AG//&-05$'B52B.F$46DA-=FG6>A:A085&82>G*@!DF:'42F=H=>";14@$&=9!G57A6<-!926DA"'E;#.!4(?*+@4.58!&'0AF-'E/E70(+=B83>8(-6,=/4)!.7HE58E8!@F?)680
@r2785
GACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCG
+
8;?GG)C/<(CBH!$G6'*./%E-)C(@D@!?>@)A6211;@8986F-+.>7G?:0-9,<A=!*1192.5-23*09!>D&C;.0
@r2786
TTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCTACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACGCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGNCCGGGCCGTGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCNCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCT
+
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
@r2787
GCGAATTAACNCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATT
+
3AE&"-1BG+%H"3&07=#FDF2;A&2C07H&0A*%91'+"!0'$D2&1*BG,#1%FG8C'5F#6)B0.?=8),#C"#'A8A-,)B04?<"0E9/%=$,6G3#/.EA3A<D3'
@r2788
CTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAACGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCANGTAATAGTTAGAGCCTGCATAACTGTTTCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCT
+
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
@r2789
AGTCATCATCGCAGATTTCAATAACATCGCCCGGTACCTGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCC
+
-GA3%#-8B8:B))B0.?@.B;)8.E6#?C:+D;:4>:0"%C2%GC(/>(,9%<7'#7+;1%)*#F"$(G)@??)4D>,!<*3G01'<<3-#%:),E'>E11('D**9/'9&-<4(%GE:+@9;@;-E
@r2790
NTNACNCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTNTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTANTGCGAAAACTTGANCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCAACGTAATATGGTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCTTAGGTAAATAACTGNCCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCANCATACCTTCCGAGCCTTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTT
+
"##)+!"+'+%)"(+'$$&$&()&+&(+""$+)"*)'&+%#))$#%#+(#)'%)!*&%$!"%*+++%'*("!&'#!("$%$(")"''"('(""%&'(##%"&*"(#%*#&$"')%*)+#"##&$#!*)(%+'%&'&)%$"($$#$!+'(%#$%'&+&!'"%*+&)+)(!&()$)(+!#%*"##"!*)*'"'&%&"*%%*+%&!)%*+'$"*("$!"$'+)&!*(*###"()%)##(%$*%'"%''*)+#&*(*)#(+*#&'$)$"%&+('##$$#)$("%$+*&!#*#%+(*++##*"$"*$*%!+&&*&#()#*'$#*%!"'%')""#*!+#!*%&!*('%)'!+*+#!"%)'(*"&(#'#*"'$#)&+%!$%*'&#(&%#"#"'$*!#+'!#%$#*"*$!)$*!%%+!'*!+"&"###&(#'##%("(&&&"%*+###!#(*#"$&&*#()&*#(**#&&*$("%*"**#!"&%*$$'#+++$*$*(#%))#+!&**&$*$%!*&+!$*&+((%#!*("''$'*('$$&%#&$(+%!"'&'&$'"&(')%!)(!+!)+##&)+!+"+%#$+)&#((!(*#++!(%&!$"*+*#)$$%+&)("&#!#*+!!%+)""!)!#)(!%*)((#)$#**'%#%$'$(!'#'%%%(!%!()!+'$'))%"*%)"+'*%($&)($!)"#))*"'*%%+
@r2791
GCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATTAATGCGATACGATTGGCGNCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCNATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTNTTTGGTCTGCTCAATTTTGACAGCCCACATGGCAT
+
#7F639.B*!!HC"$'#63;8.";/C%?+/4<=<?&1,18D/B8:#*@9&4<(F4)=*B)&)@<.G6<8-A0F6H))CB:'8:4+D(F7.#FD&$9#H96<'!:BF*";F+21=/-;.4D;=,;B+9$,H%-;:04DA6F-:;1,3'67+72E/5*;CAD@-:97:4%-2,(/C"%B?7#,"#>B/=C36HE3+4=0&H,$*'H:D<4'G9H&4)&$H-6$"5B/B
@r2792
TGGGCAACCATGTTATCCAGTGAGGAGAANTAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCATTGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGCCTTGGCCCCGGCGACGCTGGGAACAATCTGAATTACAGCACCATCAGGCAGAGTCTCCTG
+
$&.9$D&%36E!3(D00@=5,C89C;1#(7%H!$)79='H:DF.9%=D4&'&9/811:/$*@F#'!/=?7@.<1"8?.#E+#8.*F<<3>!<D.DAGFB6<*,6@+819%6C=#2@#/9!@$59<%0&FE6/?0D62:9)/;?2(,+8HB&5%881>42H->?C.3H-?D9&69#=B825=;-#">5#9@,)0*$B&-*6HFF@#HH+!B.<"/2)G,?-4+"<,&#/+?D-"==%<<0B2<5H:0#+A)?<&G.";.#&"H#%6$=G9/4B921C&;8?%!4.*GB?;D!-1D2?#69F8G0>50-#F5E4?4G45GC%
@r2793
TCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTGCGGCTTTTTTAGCAGCGAAGCGTTTGANAAGCGAACCAATCNAGTGAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCNGGCGAAGTCGAGAAGGTCACGNATGAACCAGGCGATAATGGCGCA
+
,972=F?+28@#@-91='H6+B9'E=*F81%A)@)'B=<E3FC"#*!,+8%)-F#655$60)CC5'1"/,,GC0/"4G;'G+EF;:C*@?4D3D1!2>4><C.=(/-B:H*>!->=C21G3!);0"G/?,3)2-13@@45$3;#.F>+/G=+!?EFG'0F?2-%5F8?+G."14&&A(C#.%,")G3H.'A9>4,1(=B9,C>H/:"#&17'!27&4>D,*"
@r2794
ATATTGTTACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTCCCGTCGGGTCATAAACGGCAAGATGCG
+
4AG%@59:B6A.<8C5?&A#8-82%4'<$G4>BE$HC)!-D&?4*A53DC2".!"E)C.#$7@,4D<C&%)4B.:7$C7:(->4AGA&<!>B$6!C4?:7<"9(<3/6D2&/?:F<7@F;*<-'G:>4D&1?#/<8332
@r2795
GGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCC
+
C,(84!+'6!8H-=&F"?::6C%">%2D'D547*-)0(,(2HF.;#4&E>*+,7,8DG=E74:/4DE,/*B#>H7EB;-@71.H8<4=9D"?!8-87=(!)!C*E%,2@D+G.<!?(*!5/'F)HC1>8DDGB0&<8=:@8+9@!.C1'.D=11@-E?=*.<&.9*6',233;?'4;C;5G!F>E:.#30>/59F$9@)B>=4(>=.&93?F=C0G?=$:$;%'577><%+B9F8("!D*,.5F0"B<EGB*'4;-E%.H-'6";(G3&A9<-'<
@r2796
TAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACTATTCTGCGAACTTCAAAAAGCATCGGGNATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAANACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGNCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTAC
+
E3C</$&8=:#?#DDA/45%E%'&CB$"E+5+H)0?3:%!&+97$0G13?>.E-1)A*.C1.",*(+589EFE=/CF//'F7%D@>$E?,7H.!+;D73#ACF=!FG9:71B5.#@8"%8C&.;.GB$*";42,+2=,(F?7(A997-+3+<"42&+"G&-:#*@D4<73B=0(.,*+B*/BBFGA#$2E(*%1?0-=F;5A0&BD:@)!,8!E/#5&?.%5>+$G=F%$43:*-3?=1-.E:)D5$%$G.?%:F?FFEFH"#<06F=C0'0?&1H68#'669AH77>D26:7!4&+.F0'!7!/E88;+05!)'D*G($&$"019'"B852>=431.
@r2797
TACGCTGTGTGGTCAGGTATGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCC
+
)4&D28$E.A-69'+?AB=26)0AH07#@(H$D@B<HF%4'>%'1@@G?5*:!*(D0D57<%
@r2798
NNNCGCANACGGGNNTGNNCGCCAACAACATGCCGGAACAGTACGANGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTTGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGNATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGC
+
"'$'&&""%$'##!!!((&+"#(''#($+!&$+*&%'&*$#""")'$%&'(&*$"$&"#(!#!!#('*'*!!$$&")'$"+)+$"*)'$"#")!*(+$*'*)($!*#(&*!(('+'$!%')(++"+'*+*#+&!+%))"!'+'(%&$$$*&!$&#%!"((*%)$"$#(+"+$&$("&(""("#'(+!"!**#$!!%"!()&!*&&(*!%"!%'!&#($&)'*&)*!'!)#+%%($)&")#(&"!'!#'$+%'+*"!!$'('!!'"(&)%%#&!%*!%#)!'+"$(+!)"&))(!%$$!((()#!+(#+&'""!#%!%!!)&""!'$)($*+($'#%(('#&#)!)&)&&!%("#)$+!++!+'%%$%#"%!%*$)"+
@r2799
GGATGGACGCAAACCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGNCTGCAGTGTACAGCGGTCAGNAGGCCATTGATGCCGNACTGGCTGATGAACTTGTTAACAGCCCCGNTGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCT
+
DC!').0.)(A0D!$04"6AB01%C$H3#H<1/F.C.9!()&#"F0BF?0%9*)E!GG3<?F=6(GFC<20%#F=C#HD5).>?G18<</"(:B62)!AA)0,?3'&E)19#7@/D("/H?;:6!8?8+>/C*)?$G26E!&A6F9<9;1@0HD8+G,=C:B=-=%F/+3,=8<.#B:2A*7A5.2H6FBFGDC6+E=8
@r2800
NCGGATTAATCTGTATANCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCAC
+
">;@"B4=EE,<&>6#0%5B./=B4%,>#,;4D;;,<'-**G0%)5A.E/%BG8=7D#@:!G?<9/300=-*9@5;5@%'F7.<<&3<5/'A5)E@6#"90->7HA>7.G,GAG$&7C;;:,,7:%4HC#+453/>E$!9"&94-E%1+%"&#E."'.<'*H**A(:,,H<:7;936;A'**'0D@3/97@)<?!'<2'7.!":37A#297*)>:<&
@r2801
TTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTG
+
>.3A15B*$54!-G33G7=,?<89?3;G9C)%54#*'@G-
@r2802
ACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTGAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATCTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTTCTGCCGCTGACAGTACGCTTACTT
+
=(B*F5@E)8<41C%B%&H4C46!4G:#78G9G:!1;$%0A%H<;)$"FDF"!DB+DB!("#7D.$G68HD7=9F&,&3C-B6*H+<50:E6%F$.=2'(%,(68@E=73;BA%778?F=%;E46G5@9+8C6C,B5:/+9#);"H;!4H'*96D-8>2?1?03).38/%/B3&*&6,&/-6377B>/,F!.*"+B'A0$+3")<.2#%G4(B)A'='6CA2(E>?>E,H+E<:HB;0)E@C&)9>;2>2546,<-8,&B,;,$<?4&;'$>,
@r2803
TCTNATATCCGCAATCTGCTTTTCCGAGAAACAGAACTCAAACTGTACCGTCGCGTCATAAACGGCAAGATGCGACGTGGCGGTTATCTGAAANTAGCCCGGCGTCAGGTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCTGGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTNAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTGCCGTCGTCCNCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACNTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTT
+
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
@r2804
GTNNCNGACCTCTTNNNNCNGNNTNGCNAAATNGCNNNGGNNANTGNGAAAGNNNANNCNNNANNTNNCGGGTNNNGNCNNNGGTNTNNNCGNNNNTCCNAGGCNTACCGCNNGNNNNNTNNCCNGAG
+
"$$"#"$##"$#!$"!!$!"!!$$!#$!#"$#!$!""!$!"#"#"$"!"##"!$"$"!$#!#"""#!"""#!!!#""#$$!!"!"!$$#!#"!!"$$!"!#!$"!"$!!$#!"#$"$"#""##""$$!
@r2805
ATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATG
+
&)++#*"+$'+!!"%+*#%(+$*&(('+$$+(")$#""%%'#*''"#!('+('#("'+%&%("+&##&('!+!%&$(*(###'+
@r2806
GCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACTNTTTGCATCAGCGACCACTCACCACAACCTGAGCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCGACCAT
+
#'$+!+#''*&!+)$'*+#&#"+*"&*!'*$"%+!&&*($%$&!%$&%(!"+$$)#!*!%%''*#++(#*!''#("**%$$&&#(%$*)('&!%$*!%&*+!%$"+""#&(%)&'%"!+'(!*$(+%+'+*%&')("!$%(%&%('*#'*'+)&)#''"&$)'!!&%#)')+!#&"&*$'&#
@r2807
TGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACNTGCCACACATGTGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCT
+
1&-&699A!$.<8/<)@+(!>BC>$"507EH.,</EB/:(84#(D%H@+(>)?H9&,;969*0@4?8B79=5/)("G=*'2<?F:F)/F$C+E5F?9@E/$6"(0#+H)FB':B-3%?+*)H6,#6,55F+<8.-E*F'+'6*-59,EG$B)/A3--$#FB84:<D">.>A3%.=C*
@r2808
GTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGNCGTCATGATGGCTCACAGTAATTACGGTGCTGCGNAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTNCAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTNAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGAT
+
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
@r2809
TTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCGGNGACTGTTNAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTAC
+
@,<:A*>C'%@';8@(B/E;>#+@>D$E/?GF/4=;?0*,3D;%4=H8D:*;A+46*3+H:+C&624%GE)A!$&#&HC#C(&3?G"@9&*3)A;!+:>A-<BF).*AB3=&!7(A!246,*-;C2;BAHG;(A>'=;?<E/2!7H1ABF>%0%6&>GC20$@%12)*?+1;1)-31:5F,7(=4)=%BB#-C$'-,8>E>(+G/86B$30+7;F:FE%B@5!%&#&)16:'%/;?3E$75B(8(E!9$-B1?4A75?5)---'F3(8$+H/&B==8@7<?H<1B%2E7E(=">1BC'/H-HG)?68:
@r2810
GCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACNCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCT
+
B6*8>2&>$)/+CD<97D!G3/#B1EB4%.,>(=@:A&@:6D8#=;%::C#D7:9;@4#DD%>*E6&E110%8?-(@,E;;EAC"C@;H=,#(329B<7,1,.
@r2811
ATGACACGCCGATCACCCGCACCATTACGTCTGCAAACAACGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCNTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGNCGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGNAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCGGCAGAACAAAACGC
+
-@3=HEG>E,3BE'&.!"&*1;4.6F7(#F%A8E5%71G#2%*G@%1;4;@,+69G8$>-1D5=$)A59@((=0(*&,)4$.HB&#5<9)#(7(#G/!H$%2!<F*1&$1A>CC5?%)##;=2+'&2)D4)1,04D9#DC9CE@/8$6)!A&(<*!'1.:.-=D$GEG@87EG&.F(8@7?/+&)F6-E!!%#@7?F>:4GE(*F2>(=.8&(,2:7*$>0A/8?+C+)*@,!/,@;*@:=0@:D"C5,"G)(%+>:@G%-<.6HCC35#0)('E;E>D(),E5:EAB570(+6&3@:-,%*,HFB
@r2812
TGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTNCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGGATCCGCCCATTNAACGGCGGTCTGTGGCTCCGGCCT
+
F6;'H&H)$,5-9+FG-@=6+.342??!,8B":?9#/E$&5"=86?.5="?))/B2>=$G<'+FCB)=82..#.H159/2(%/;*4639!+;*B)GE>682:>E-FA0=>F5/:E>H37G4<1?A)12?5".?3))9D0;!/'!A7AEB@?@3&)#G*F-'522(F,G)-9*(13:6?"?)
@r2813
NANGGCATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGNACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGNTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGAGGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAANCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCNGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGNGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTNCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTANTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCNTGACGTTCACGCTTACGTCCACACGGCATTCGGCNGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACAAGNTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGANTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACNTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCANAGTCGGTGGTCCGGCAGTACAATGG
+
#'#!%#+&*##$)*''"'&)&)!('+*"&%*)*#%#!!)&(%)!)%&'&#%*%)+'$$"$$))$!*+&"!%*#'+"(+!$*+#$"%$'($*%))$(+'*""*&!*%#&$#)*)('('(*%&"$"+#(!''!('$(!")"&%%$#(*%$%'%+(%"+$''+##**&*(&&+($"&$$")+)'#$'+!%#("(#))&)&&$(&!!$*$!')#+)++*'%"#)#'#($'%$"''+$!+)!$&+$$+*%(*!%$*)#'"))+&!')$'$$%'%)%#*"''("+*#")&!''$#)&$*!'(*%&!#!'('+(!*#"$(!!()+)"!&""*!##*!"'$($+"+)!)+"%!+*(#&%%)+!**#!#&&)(%+)+##'%'$%())!'''#"*!&$%$#""+&)*#++'"#($$&')!+!$+*((%+*+))$#$"##+!*)*&+!&%+#('(""+!&$+(++*&!(#)'"+!(+(''"*&*%#&+!*)(#)')**#'*#&+"+&+)+')#$%$!$'**#+""(+)")%)'++$'*%!!*%%$!("$'!'&&%'*!("+%$%#%*!#!(#(+"#'#$'"''!#%$((#''#((+)+)$""%'"$!""+"*#()*!%#&)%&++*##!"(*&"%#'$%!$)+!*)&(!#)#+*&%*+)*)&(*)"((%$'#!*&$+&'+'$&!*''$*"&$+%+%$#$$!"(()&'"*&)#'""$&**')(!"#%#&!%(!"##($)))%(!(&#()(#"%%*"'$$)###"*+"$&!%)''*$&*%'!&()%#*+#%+&%(&*+#%&')+)+)(++$!#("+#%"'$%$"$&)#$&$'+%!$*#!!")'%''!++$(%&))(%%*$!!*($#"$'!#&*%"&#'#)$+"&++$'%*%!"#(*'%$*")&(%*)$&*$*"&%$#%$!!#&*$*"'$!*"&'%*&&$&$"$('&!)*"#*%("+#*$#("%*%$$$#&"$'(+)'"!"#"!*"%!+%##(!'"'*'''()++((&*$!'*%)$+#"+$$'$*&(#$(+#'%+%'$)&#$'!!+*++(+&"%"($&$'*"+(+)#%#(!#'%#&*)+&!&''$)+*)()"%(!'$*&!%+&!%%#&)()$%)**&%(+"%+#(#+!%'!!#'*"'$'&((!$*%!+*##%)#*&$'"*("&#('&#(%$())$+*#!*%*(%'"&&##"*!$)$#%%$*%+$)!*&"#%$(*'*&')($*('#$"!+)()#+#"+%+"*#&"&+)+)")+'$##%)#"&*+$')%)+'&!'%#)"()(#))&*$%%)&#'""%'#$$$$&*+"'+"(+'+(($$&%+%"'$$+&!$"*"##+%+"*!&%+&%$%$##+('"!$#*+!))+$)!!)#"
@r2814
NNANNANGNANAGNCNCNNTAGTNGNTGGCNTAGCGCTCGACANGTCCNCTGNGTNCANGCNTANGCANNNNTANTNCNGNNNNNNNTNTTNNNATANNGNTNTCGNNNGNNNNCATNNCTGGTCNNTTCCAGGNNCTNNANNNCTAGAAANTNANATNNCCNNNACNTCNGNNAGGNCTNNNGCNNANGTNATANNGTNNTNGGNTTTNGNNNTNNNNNTGNNAANNNGNNTNTNGCNNNNNNGNANNNAGTNNTGNGCANTNGTNCGNNANATNNCGAANTNNTCCNCTGNTCCNTTNTNNNNNNANCGNNNNNCTNCNNNNCNNNTNCCNCANCNAGNTTCTGNCCTNTCNANNGNTNTCNTGTGNANCTNNGNCCGNNNNANNNNCAGGNNNNANTGAGTTCGCANTNCNTNGGATGACTTGNNNCTNCCNNGANAANNNCNNGTGNNNNCGNGNTNCTCGNANNTNAGGTATNACNCNNGAATTNNNNNCNANAANNANNNCNANTNTNCNNNAGNNCTNCNCNNACATCTANTNGANGATNGTNNNNTNCNGNNGATANNNNCAANGCNNANANTGGNCNNNCAANNCNCNTCCAC
+
"!$$$##$!"!#!#!"!$#$##"$#!$#!"!#!"##!$$"$$#"##"#$"$$"#!"###$"$$$"$$$!#""##!$"!"#$!!"!#$$"!"#$$#!!!"!#""#!#""""!!""#$$!!$#!##!!!##"##"$"!$$"!$!"!"$!#!!$!!##!$#""##"!"#"!$""#"#$#$"#$$!!#!!"$##$!"""$"#$!##$$#!"!##!#!!"$$!!"$!$"!!!##!"$"!!$""!!!"#"##!$"#""!###!#$!#!$""$$!"!!##!""!#$"$$"#"$$!!"$"!#!""$####!"#$!$$$!$!$!!$!""##!$$$$"$""""$#!$$$""!"$#$"!"$!"!"#$"$"$!$#"!"$!##"""##"#"$$!#!"$!$"$$#!!$!!"!$#""!"$###!#$#"##$#"#"!""$##"!#$$!"$##!"$!$!"#$!!#""#"$"#$#!!#!"$#$!""!#!!!""#!!#$$#!$!"$!#$#!$$$!"!$#$""!#""$""#"$"""!$$""!!$$$#!$#""$""#"!$$!$!!"#!"#"#"!$##!"!#!$!!$!!!$$!!$$"!#"!#$"""#""!$#""!"#$!##$#"
@r2815
GCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCAACGGTACAGTTTGAGTTCTGGNTCTCGGAAANGCAGATTGCGGATATCAGACAGGTAGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCNATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCNGGATTT
+
*+H(5'?(A!46-;$+0"(9$'D%6>@.$)/(%?=G+56;?@G->H=0134&>+,+?E:+<E;3?C5,0%A3E0@;8@$#/(6-F0?>>?5H(#"8B$%H:8-@$2H(2;5D3F&#18"9@*B)E9=-8-(GF5,>@.+H'+%<G95.;$%7$B&@6.7&B9,'6<,;+97'E!$!4'A1!A+3.?@'+D"'"1*:B7;>"6.:6)),!4260BH6''>?!/9&%%*:9&?"*A6"H?B&=?.@GCB!<#%-4HHE827?E%BA2+0A@%!:1$C1:G'448F'*E@B1)G$-/;*!#C8#FG=E*#*#-H"A6G.2-;AD775!C:5+6F3)!"&>?(:AG44/-&AC?)&6?3G!=H+!<?B&B?"$1=3"@BF%36238,EH7H>,@).?2)$1-/DF?<>"/6,B/FE(>!7;"7H)37$<,67>/6E0&3
@r2816
TGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGATCCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGANAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGG
+
%2C2*?&,.&-=+HC$F"70DG9E75(F8E<9D'BH7+3!9C40&A228F$A-HB,C5+3?.6EB<*<HF@.D(>:&/4377C34-2@,')7#C*D6G@A=$=DH=B*9.FD;?D&6D0<A)87B6)%($/G:&C"H!;H<4,+"0D=.&#D%@5E;(3976&:?G%A2#D'/?!$(6F,91@46F/<FC1G60>B"@&>H4FF!'*30*.F=@12.&&+:A7&.D#+3D3H5G7<,"->CD4DF'"A?#6',G$:;/'701C2,#@)597;HD!0,A(-52B%H<!*-+G!(2/G>5>H,8#6,!E&A"?&#$7+?.3#>8A3*G5B3G/(<"4>D)D"77;(*#>0B>11%4D9HD),=A*CB6G2-#D@G<'A?G(@,?>@.+:694BFDE7;E/):>39B?.@;#0+:?@6::4C6=/&>B'>G-%0)G)(#5!*$!
@r2817
GCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCTCCGCCAGTT
+
>(H.6EE2D&#2F)=&:+0-9FAFB9E<6$&?<:7A3,F2F$(A(=G&*3,9%AF/79.,-"/2%(#2*2G0!B><!9!:25HA8&/D4-1D*8!8:3(%0))0#%*A18:EE>!E=*&;;<D7);8+$>%<-GB$&'?9A#&G,,)/':8.F.')0EAG7C4:&'3="1C.@D+<FB%10#$3F<%;A/+,'!#1&.G!$+?**".''8%./,-#&1H5<4,H/$(4-5G917@().738%"9>+=EG!*,9,2<"":G>;90$#&2/D'8'2FCH!))A4;/6>G&*>5G)>".";!EH<!"2<6H"H$>*(,'?*'*-A/11>&1B=E04#"3**HD<!(0!:7%/262""7"05H?GF/19H"AA5H1@D)1-;3!G#@B$;>+?/9"'6C%'9-B,H9B&.6>
@r2818
CTGATCANCCTTNTGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACG
+
'&!$+'%$(()+)&#%$'"#*"(!'"%#!)")(*"$(+(*+!#!*&*$*$!"#+!+*+&)%+&))')&(&!""""'#%!+$#+$'&'*+$
@r2819
CGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATC
+
H!;;75F:5>)?$F3.C+E1F()8-$E37*#"<$-:GB"@&2#F*&"1F300#:;>.#:<9;>*3'F8$7=@#(62D)H9$2;27/H5'!-57)#<>;1).(?)$4:/?0-536C:-2&D4/?C5A#;<("++F368,&?E73).H11A-?1;C2F6-18A9&B73HA-#29?.("$%D=-(%>$%+E!F($-,/!43@E>(1GA%7?44#/@
@r2820
AACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGATGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCG
+
C4DF2'/.<#5F8,?!1&?;'0<;"!9?5'?9C%"9<(E,&D?5(/+<%/%0GD(2@A;99D>+B"A:B;''8AF)?<<;,8=EB=6-6!:/1(-C:&@G:>%"E-00-;?F1B>E,&A/+'A7G5-(+;>%"9,,!/%"HB3C!!5#3#'G
@r2821
AAGTTTTTCCNTCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCNTAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAGTTCCCCTAAT
+
:?B$G0"9@&9$5C&(///A=/%)(0='*'2!G&,9,0A?.+*=HD8-(6HB6&8B=#9+*&3H-G)#>:3,C><+'%+*.B0A/0:/&H;<93'2'/>:36F,B'(;$=0-!";"G:11=C,"!-:/7%12E7&9963C;<0)-E0C''61E!@E"B<DF7$6+(5!>*%-C?#D/+DG,*:,21?'5/F6%7&8(>+11+F'5&A&,/#(C
@r2822
CACCTTGCCGATCAGCCAAACGTCTCATCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGATTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCC
+
1>%%35"6',#8!=6$B*44;'A9(7D<-$D5D:.F,8E;F#B3!;C!&+BBA*H%1<8E&3"-003!69;/B4?B-3&4'#%!(.*368C:3$-:#/3DH63<##G9A%#E$/52F49.20B1;@G+A2'4"3+*)+;6600'.'(6+8&)9B/6;+/-%/<?H+9E66?279A&F40+6$0;>-6*89F1)*E"?6(E%9G,<C;5EBH+%$H!G8#;.$!&=C7.2"H#G6&/B<.);,<2,3>C;++-')
@r2823
GTGATGTCTNCATTGAGACAAGACACCGGATCTGCACAANATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTG
+
6/258166>;:@9>D:3=+-"24H51.?09(#FB6*A677296.8>:<*+0D5<</B'?BAA&'(=G>">C)&%ED4,6"2E
@r2824
ACATTTGAAGATCAAGCAGATAAATATATTTTTNGGCGTTATGCAGCTGAC
+
/D,/BC5D8?6/H@&%/:1F@3;5:@10E+F1E9'7>HG(FF@?"=6*C,H
@r2825
TGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACNTTCAAGAAACTGATCAGGGATAGCGGTCAGGNGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAG
+
2)#E'2.E&@4F91(;40?)GH#:E=4-7".B3<47-F?6'E8:7)#1-8<>#D!,(1C%8523C)E!B"/1G32A=9?;*/=!->!;;>$*=F"52G&73<DC39-?*70D<>A:?<<//$29E"'6+<C3+*3%A)B.0=2BE%/$
@r2826
AGGGGTACACGANAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTANTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCACAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGANAAAAATCAATGGTGTCGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGNTGCCTGATAGTGGCCTTTA
+
*59&$@-!G/$(%00#(A7A7#/>B3?4*0)#>2*"D86D)#!116F#G;#7.&->E48H'>H!4@HC8!)@3F"'5".-AA)":*3FB'48=7F#GC;21,B3@6?'H,+70+").D58&<,1'E'E*=2/-G1?=!G*1#BDFC?F14A@*##)0C*(:0F&BF=*&*3E";3-4&&>!7C)A1=,,(@$/-B*!@BH.7,E>79A*1")80>(5'48#H,='5:'5HB"%1<B.H3F$(%AG=7@;'"$"0F22#()&*F.B*1;)A3)+B8>4&?.8779FD:"A*-0+F3"4,@8);5B*-7$D5>!D?4>D$(:(E&"=:9-DF&7&*2+43EH-@#@+H%&ED03CE94A6D;>:G)$7D,
@r2827
AGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTANGCGTGCGCAGGCCGANGCACAGGAACTGAANAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCAGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTNGACGGGCTCCCCCTGTCGGTGCAGCGGNGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGANACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAATAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACNGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAANCCGCNTACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGT
+
EC?6)-E'3BAC>1A;9'4,>)9FA6*D1..<E$@&7(H!6&?16A,(7C@3+F&$5BA,'$F.5&H6*AG(>$.0$5&(;E"E,(A&8GG5:3/)2.D#AG'=F;7>8<!<#0@(90+72F2,8:>"=8:@/C=6;FG<D7%/8)%HG7%:)G*+3&C"BCF.<:5<C/'?7H85D*"5DA.:G"%D2(7G*8>5((FH0>;%C#%".AC?G%A=-C:@2-658?6B)B->/6":%5GBDD,#-64C7'B$$@G7.%2@%1$<>>/%,>036CA91E!=)>-*C+7<'?A(A/A"%!#-=;5'7D;-2@G*?.%C?+612$B&$$GC:7E*'42">;H1=D44%(G!5DEDB%3%,++2G'8$!F?;(&@<=C/)'%)8,+:*FE-7B5!F<H,6;::HD/H,*9C,&6*F:,(->A$B%G!%72D9,AF501(!(;=+B$4C-(#)1.B6'+15'E'":,#<A-;7-1G<BH%:&-4"F$?GA5#/4=:"*?!A!&FH<.$3>G$29=*9B4@
@r2828
GACTGCGAGNATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCAT
+
)(/D*-35&)/A*0(AB9-)4#C!4';G80&094*&H;-53<1=%A$!-4D"C80):C@8?8.00?&,<'C@1F9&<>*%%8F*4?"6?A:54E/'@A78<(<H./:E8H91,D'(62?**3'*.7=,;F,*)H02,.EE:/2(*AC?":"E5(#8:6C=C@;D%,:'3"+*?D+&9B4)>2$=@F
@r2829
CCTCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGNATTTCGTGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATNTGGGTGACGCGAAAAAATGNCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGNACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACNATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATNCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCNTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCATGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAAACAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGTCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGANTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTAAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCCCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGA
+
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
@r2830
CAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCNACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAACTGCCCGTTTACCTCCCGGGATTTCNTGAANTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCNGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCATCTATGACCCNCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTGTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCANGATAATATCCGGGTAGGCGCANTCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGNCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGNCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTTAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCAGACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGNGGGCTTCNTATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCNTTGCCCGTCAGTCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCCCATTCACCCTCAATCGTATTAACCAACAGTTCANGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTGTTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTG
+
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
@r2831
TGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACNTCAGCCTGCGAAGCAGTGGCTGAAACA
+
F"0"04)-+8&?,H,$@*<>6-0%"E0963+,D?B*:*6/G"*4AF!+H3%$8"A?GE1,#8</:1CE90!B6:#")E
@r2832
ATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTTATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATANTGCGGGTGTTGAATGATTTCCAGTTNCTACCGAGTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTGCCACCGACCATCTATGACTGTACGCCACTGTCCCTGGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCGTCATATAAAAAGTATT
+
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
@r2833
GACCTGACAAACACAGACTGGATNTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGNCCGTGAGNAGATG
+
-75D8CF,@$75/!?"D%=7F=5,<&<E#*/G(7HAH"40E4*+.H+?2173,-=9##HDF79;B/-#+'1/1#,*8(*&6&C$2'
@r2834
TCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACATCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACNGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCNCGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTNATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACANTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAA
+
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
@r2835
ACNTCNGTCGTNNTCTCCCAGCCGTTGTTCGGGTCAATCNAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCAC
+
##'*))$**'"!*)'#+*+"!+!##$+!#!$*#)%#('+(*)$&$&#)$!()%#%(%*#*(#)%(+)$$#*#'*&%('***"&!!&#"*'!!##&($#&"*(%#)"!%$***(%*%%"#%+#
@r2836
CAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACNCTGATGTTGTAATTGCATGTATAG
+
;701C"E87(G':,5FA)-0&$!#)F,0>E1%GBA/1/8%H:8/"*8'F$?A,""D;EBG3*+(AE+H"&?)37D:-+1*'25/)8'F%1B>FE9?#GA.
@r2837
GGANTNTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGNCCTTCAATCGCCAGAGAAATCTNCGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTGCCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGTGGAGAGATGGGTAAGCACAACCAAAANAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAACTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACGTGGGGGGGATGAGTTTACNTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGNGAGTTGTTCCGTTGTGGGGAAAGTTATCGNTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATA
+
#'("%"++$&'+'&#*&#")(+$'+$&!$'$"'!&++"#&$)*$+*#!$*)!$(++($((%""##*#+!)!#+)&&#(**+&"')%'+'!*)'!&#%%%")$+'%'%$##$*++()$*!+(!"!&(!$)&'*&#"'"!*$#(!"#%$*")'+)&&+!$'#""+'***%'+(&$$&#((#)#*(!#$&'*(+%%(&''%#*+'"!%&%('%+"'('#*)*"'*%")+$(+&#)%+#&#!)***#*%%+'#'(*("%#+&"*#!*%#%)""$)**)+%%)%(+$#&"(#%#&+%%!!(#%%%$$!"%!(&&&&##+!()(*+(##()#+"+(!#+*()'%""#"#!''')#$#+#"!###)#)('$'(!%("%""))()'!!)%#+*%*)!#)+%('$)$*#)!$%&"*($#"##%"+)*$'!)%%&)&$)$$')$&&"$+*!'&(%(&'&+&$!)+!#$$$#$+&&*!)*"(!!*&+*!*&&%!)&&&&+!("+!$!"#)&&(*"&)+%*&+#''++)$*&&+(%%*)!%$*(&)"&))*#)*!#"$$(+*!*&+$*+$&'%*!*"$#')(*!+(#)#'!!$($+&'*''+'+''**!&&'(#'+((")(#)+&)+"(%'+"((!**(&'#$!$(
@r2838
ATGNAGNTNAACATCGNTTNANCNTNNAACTNGNTAGCAAANTTAAAAAATATGGTATCTGTCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAATTGATCATCAGCAGGTA
+
)!#(*"%(%")*('*#!'(%'&&$$%&*'*#!'#(%($'%("+""#(#!)%+('+#"++%+&!'#"((($($&+#&##!+&&%#*+"*#*$#%#$('#&%+)!'')!$*$"!"*')!'!#*(
@r2839
ATCAAGGCAGAGTACCAACAGAAACTCAAAGACNTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTNAGTAAACACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGACAATACGTTGATGATANAGACGGGAAAATGCACGCCATCGTCAACGAC
+
)=533?2B+E#G1?3BG:09:(G/6?'>,G71,*=96294+8%(8G>2/C%G?D&7A&%;G<@!6->1E@<63*>%F1"'C'=;5)!-'!H?(=4-F1=<F/+15=;BD0AFA!:7G3!)F00$&%)='5)1#")"D57@38>9*)@B61)G,,8'F2)7,A@@&CC>3/E8-"3G+;.8=882"E>.#E)#DD7&$?B&=.4F=85>!
@r2840
TNTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGNTCTGATAAGCCATCAATCATCATTTGCT
+
((++&#*$#)$*#&""$##'#($*''+!("##%'%'")$+'*&*"&$(*"$*$!)%$(""(+(!'"#$&%(%)!)"$+!('+&%$+$!*"%!+
@r2841
GGNTGACNGTAANCCGTCGGAAGTCCGCCTGCCGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGGATCTGGCCTCGGTGGCGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGANGACGCCGGACAGCACCACAGACGAGCTGCAGAACAAANCGCTCTGGTCGTCATACACAGAAATCATCGATGNGAAACNGTGCTNCCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCNGCCAGCAGGTGAGCCGTAATTATCATCTGAGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGANCGTTTAAACCGGCATACAGCAACAACATNGCCTGGTGTCTGTGGGATNTGCTGACCCATCCGCGCTACGGCATGGGGANACGTNTTGGTGCGGNGGATGTGGANAAAAGGGCGCTGT
+
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
@r2842
NCNNNNTNGNGNTNCANCNNNNNTNNTNNTTNANCNTANTNANNNTNGACNGCCGTANNNANCNANTNAGGTANGAATNNAAANNGANNNCTANTAGTNANTCNNTTNCCGNANNGNTAGCACGNCNACNNNAGNCAGCNNGANNATGNNGCNACNNCGCNANCNC
+
#$$!$"!#$"""#!$!"!##$"##"$"##!$!#"#!!$!"!$!!##!!$#$$#!!"$#$##$#"!##!$"#!""""$$""#$#!"##!#!"!"""$!$!#$!$"!"!!#!$#!!"$"$#$"##!#$!$$!""#"!"$"#$!""##!!"##"#$###"$$!""!!"!
@r2843
CCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAGTATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCACCCACACGCTGCGTGACATGCCACCGGCCATT
+
8&%7@8#251?+<B--EA@A:F3+9;)0,@46&3CB&D152EA(;FE7@5)5B),<F<028)(<,4#*!,45:-!'=3H%#0%"=$.;@AG%31;1:@D7''G18%D((5+!+)&B,7=<8;##C*H+3C)@0-;'-D<6)E)HC%65B
@r2844
TTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGATCTNCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGNAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAG
+
C76@D<1(;B#D,CG1*7#'A1"DHA4B9+4::2+3>&3!2B0-C!;/D"50>,=?$&'+)>'>">81!#$;9(>3/2;F,DE++)42GC>*9D#$.(6H,+@=7=E0:<CG79HE9D..B71)73-B66@)?(E3<(!$C,H6B-/><)*+FF0E?7445+H>@/9-"H;:5:15&?;/F,266<=+7!H7?"@#FC3B&E+-1"(;="@4&6&&.?58!&;78F6'#+7'@0E?30--6:&-398.*2+$E6#,A(B9H@1B,'2$8%+:"G?6/?/'7D+4,)!+DFGC%A$'*"($+>92%2@$<@&00)(#<<AE<3@*@30G&1?,23H3*G4-8-7370DB#/=33,?C3A!;2:9)A:#2'D>GE"AA
@r2845
ATCGAAAATATCCATTTGGGATTCTTGACTCGATANGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTNTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACANCCATTCCGCCCGATAAAAGCATGAATGTNCGTGCTNGGCATAGAATTAACCGTCACCTC
+
1;<,4BE4E;-5B7H3D$5#78D?:/:66$E2GF,(,791F>0*.;<(C8/F8?7#-:!3(FD'/==H)*&:1@6%;<67D/"=8&%6,7:G*9)5G'F!:7&9#!D=E0*,*3@15%'@3:A,+.E*=+%.*A.!A5*-H"+?</B011$C,<..*D1'6,')=?!?5!(:7$)G6-"!A*;#
@r2846
TGCACGNCATCGTCAACGACGTTCTCATGGTTCATCGCGGATG
+
)D2:;D,50-C7:.>C0FA5=E262'"440!.:"%=0D(.G/'
@r2847
CCCACAGNGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCNGATCNGCGGAACTCCACAANCCCGCATCATCGTCGCGCCGGTAGTCATAGCNGCTGGCCACCATACTGGTGATCAAATCTGAAAGTGCCGGGATATCGCTCAGCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCNCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGTCTCATCAAAAANAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTNCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCNCTCAATATTTTGTTTAAACGCCGTGGTNAGCGGCACCGCCATCGGGATTTTCACCACATCAAGGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCNGGGAATACGACGGTTACCCNCCACAAGCACGCTGCCGCCT
+
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
@r2848
NNGCAGCAGTTGTCCGGNAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAA
+
!&C:(8DGC>.C##C/7:D334;#"*#0HF/0)H0#0H2?--<.8/=4(/)9/(77?@,@"0276%./&G@@;,)#'-:556*"H:FF8C,E2'=
@r2849
CGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGATGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATNCGATTTCTCGTTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACNGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTG
+
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
@r2850
TAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGNAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACNGCCATNATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTNTATCTGGCATCTTCATGTCTTACCCTCAATAAGGGGANTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCANGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTNGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCANAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCNCCGCCTCTTTTCATCTCACTACCACAACGAGCGANTTAACCCATCGTTGAGNCAAATTTACCCAATTTTCTTCAATACGACAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCACTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTCGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGNCATCCTTGACTAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACNACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGNTAGTTGATAGCCTTTTGTTTGTCGTTN
+
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
@r2851
CCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTNAACGCTGCGGGTAACNCGGNAAACACCGTCAAANACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGA
+
94(!.$><*0DF-A;E$.::6E"6+089.@%,CH!*2?8H>66$!<<=;$A2;9-8-H<"!33;#@@B%<09"7HH$72430>4B"7DG=E%8#"'FH)@3,*3<<()$5=7==+%8G?0>+)'B'@E0'B5@&28'4(67E54H)&1EFHE39>)C0G<G/;,,$3=G?',
@r2852
TGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGNTGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAANCGGANATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGAC
+
?((7F"?5%+%/!&$3)G:GC,<C$.!!GC-E#>H8#?$6-H1"-&0-.!:FE'AG+H=G<>6+$H"5#C'1(A=<9GH(;67),>7:&95F8HD'*9F<G#>?+C<18*)66&>3D;H7CH&,'7(=9D/-*8:++7/005>.)2''!@(4C)9&#"H=%,8)5$(3#<43%+C//@A"(*.#-9G@E2*"0;(
@r2853
CAACANNCATTTTAACATTTCCGATATCGCATTTTTCACCATGNTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGNAGGAATACCCGCCTCTTTCAATAACGCTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATNACCGCAATTTATTTGGCGGCAACACAGGATTTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTGTATACCAACGAT
+
$))!'$"((%+#(!$+&!")#*#$"!!"$''+("(%$+*#)&$**"#+"$#)#(!)**'+"!)+$+(&")%#'!)**'$&!'$'#'#"&)#$()*%#+'!$"(**%'##*'"#+(+'!(*$&!%)+"'%)(#$*'*"+')$$")("(#"%+"#(&%***'%%+&+(")%%"&+$(+*!+!'"+"#!#&&$'$'&*&*()#$$!!'%"&$%##((%$("&)#'""*)('!!($&&!$&'&'+"$('(&!((#$('&$'(#$%&%&$(!*$)#&+$'&%$)"*))#&"&*($'%(#)*"*#)'"&)(%$##"('"("!('(+!*%)"+'!#&*"#%&)&*)&(%!('"+!!&+%("$"(*!&#"&)#)##!!#&$'#*'%(!%$&"+('+'&+#(!
@r2854
GTTTTATAATAAAACGCCNGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGANTATCTGCCGAATGCCGTGTGGACGTAAGCNTGAACGTCAGGATCACGTTNCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCG
+
F27=.<=#.%D#"23:3:<616H4"B!:B5G7@A+B&69$%#2#%3#!"F22.,2(>=>+)CF%#A3(.-1:'5=.E;+#DD!F*H=:5%:>+/<FA);388A;>?8:1)<:;9A8%?;D,@$C+70&H'#"'5:4/F8&BB8CF>?..1(<'CB#9@<9>B1B$>%#9:#GF>E9&)CF&5B@C-E@B6#0%*>#2A*HE&<C0@A@;/75CH&C8>2@,C!H=@*B5)F=@)G@%DEA3D#"AC5D.26?76!)0H/=89'+&0*2E0BG@56(=(#96F!.>#+#"BGD#G!-@F>?79;G4)"GE,?'1<-F4>0';233"@<B,+":9>1/0.2?&.6B6%*0;0:+&+/,',/@B"6$:.=',(')D"D###=&#'*(3<8"G7";1;1GB;20E3A.:=.2'29+8!'E?!+<8C/&):9*24,=</7>010$,)6(0+'#=#'*H='*)$)411>
@r2855
CTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTNTGAACGCTCGAAAAAACATGGGCTGTTGCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATNTGACCGAAGCGCAGCAGCTGACTGCTGAAGA
+
;<H7C$(*?F)7$,&B:"*1)&,3$H8;B;E@,%4?(5-%-<H04?,G=E(<32$H;97A$)-,44>%*/0:?7&=8E)-DHA@.9.9D:B*<&<5$)A%@4,C'B*7B=/22F#1()&2$)0F@AE5$A*65$0%C1#'1:6+#1>@H/G%&F"=3/%;&=ABGE-HB@*78<:<26+"*E,(97+.FF?A,'6))DCH',3)E6,&$+3B9:<=>*08H:'-&,7.B/&4-D9%@D'3+7$>*A*'*4)@=66!1:&!8F98=!+'B=%B#B+BDH.@?5##=06&$2A1&67#'H&$<)!#
@r2856
GAATGATTTTCTCTGNGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGGTGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCTGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAANAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGANGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACCAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACNAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACNCAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAGCGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACANTACCCAGATTGCGNACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACGATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGANCCNGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTNAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTAACCAAANCTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACNCACAGTGCCAGNGTATCCGGTACGGATTTGGG
+
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
@r2857
TTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATC
+
>)G/%C48/:>H81=;&CB?(:#04+*=%"7A;0$><A6('B/<)H(,9
@r2858
TCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCNTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTNTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATA
+
<>#5F+2=55-"3!.2F&*?46:;D)4&-9:'C"":'*63#6-C4>77993EA;;7<D+83H(=-9>2D,&D/4D5C%&G105&A(C)"5*GB#(3)E63,(9'$2EGF4E)D$2>-;+3FC:;"3D;/@&0A>:67,@;B4<C/,2!G+2-%>'*68"+&H6G7/6H?-G1;-*#>>'4.84H(G>H@2/6@G/F87:;/G<$FA:08=>4!9$#D&>H%'9G)!"+307F<5)F5
@r2859
NATCCCCACCATTGCCTGCTTAAGNNGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCNAAGGTCTCCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCANTCCAGCCGGACTTCAGGCCTGCCATCCAGTTC
+
+"!$"'++(+%#+++$""!"))(($&%#&&+#%(""#$)+"'$#++($*!!%"'*)))$"!!%!*!'+#!'+!")'++!&&&**$!(!'('(!&*(*!!*)&((&+%'()'#&#+!"&"*'!%!!+((!"!+%$&"$'+##!!+*%)'%&$")(###(*+((*"+""&***((*$(&+$!()$+)%%***')"$""+*'#(++$"&')$$#("+&%$#+%
@r2860
GACCAGTAACAGGNGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTANAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCCCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGA
+
6B&@)#=?6)+AGB7#%:36+%F5:>74+,H$#B?7.?19)"24+!F<CF5A@*B6#*95F#'=97?3,4>+:6$F+:$D@%FD?%"3>-;;":/8!>&&C0!F(:F1%*B=/73C29&"+.>#:E"=ED2*#.63;F?97"<C(;-7:AD#=;*;:$.GA"HHA!!%.>'3/>DA=.#:/BAG'!&FC4A='<H"$4H#4<619H98)>
@r2861
CTGNGGTTATAGGTCAACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGNTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCAC
+
')'!+$&&+#&!#+"$(*$$*!$#'"(!%*")$)&'"+!$")(*#&%*"+"($(&)&!)!&*%!)**+%!#$&)'$&&#'(""+!"+)(#&%))%!#$%&&%)##'"*&#*$)+#%!
@r2862
NTTCNTACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGCTATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGCTCAGTGAGTCACCCGGCATCAGGTGCGGTACNTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGNAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCANCGCGAGTCTGCCCGTCCTNCACGGGTTNAAAANCGTGAATGAACGAGGCGCGCCCGCCNGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGC
+
!(&%"!+)"!'%!#)"#&#($$#!$!+$'*"%%%"&''!++*%&*+)%!!"'")*))!!'")$("('%+')*#)&+*'*##%&+%&&%*%(!)+((%))"###**#)!+$+%"%+*&&')(#)($'!''"'((')'*#%$&&#$&!'$)!(#!!''+"%%)"&##!$!&('"')%*#)"$!#%%*'+*)+$%"*#!("%!"$&*'!!'$'$')"(&((%***()($!)"$&+)+&&+$#&#$$(*+)&*##&!$%)$&#(#*("$#)*&%&+$&'*&'%)"(&$')'*&(('"(++)$)$$%!$'*%*!!##&%*"+"&**''&&'%%$)()+*+%!"!'**"(")("'(%*#)**&"''(!$)*($$&()*"($''''!!&&#)'!+&)#*#)(*#$&$%#$$$'+'"))"!&##*)&*&%'%(!$#%(%)($!!!#("($!&'&*'+&))'!')'"'+"$)%(&!)#*++!)%#%$)%*)!&"**$()+$((!($'$!"++!(%*+&&&"$$!($$#&%(!'!"&*#("#&
@r2863
TGTTCTCTGGTCAAATTATATAGTTGGAAAACAGGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAANCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCNACATAACTAAGGGCATAGACAATAACTA
+
C:*&!++A2FD,E<;-$(1%=#)9:8389D2"//E5?;'8;*3H+)"2(EF;%7%86)1D>.),3F4,%0C#+7&19?-)13)9140G893<7::%3H:!7C@-9;#?C5*,:3C@/0E<-=6;@C&BHF';#9-'9B'/"&)9/H<1(D."G4>=G?C8"#*H7,7!=><C/%?H(5
@r2864
TTATNACTTTAGGCATTTNTACTCTGCTGGAAGCNCGTGTNTATTGCTCACAATAATTGCA
+
E$'6/16(=1.8.':,(18%D4:#>()&E-AA:F:-H*,(;:;$/,!?'B<0:96:44:5)
@r2865
ACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGG
+
3B2@,0$0&<D7%HE=0(=?+<+*&<=9F6D)=&3'H597/D;74D!1:"7>=/=/64C3*+1%AAB$.AAB5!"E003?G5?
@r2866
GGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATCAAAGTGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCNGCCACCATTACATCCGGTGAGNAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATG
+
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
@r2867
CCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCANTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTNTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCNATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTNGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCNGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGNGGCAGATAATATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCTAGTGATT
+
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
@r2868
TGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCGCAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGANTTACAGCGGCAGCCANAAGGTGGATGGCANCCCCTACAGCCATCTTCCGGAAGACGTCCGGGAGACACTGCAGTCCCGGATGGACNCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGTCTGT
+
<B?$+"'39#('D(;D(*("-317$:-=7GB9!5(7.@E-)9:<55E9,'3G'FC!G,<=4"?H<;$<!@=6'++B0:5*@H(<&H96@%B!B+<(?H!!?0?$G3.3*@3/+91B5"(*4(@02G82:A*D%75=8@A+B53H1!@2&-B)-$,1B074)A:@;*'12C1='B2)?10,9!?75(CC@5:;A8$"A,#$6+'%#A37886!).8E!2*A,D46<E.+;;B%%,8B2=D'-&!%-D2'')HEF"6?&$%$8/)'(D):!>!0+$%0C%)
@r2869
CCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGTAAGCATAAGCACACAGNATATGAAGCCCGCCGCCAGAAAAATGNATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTNNTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATNCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGNGCAAGGCTATGTGCCATCTCGATANTCGTTCTTAACTCAACNGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTNGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAA
+
#+*(&&%*#")*+!&!(*+"!("(**)#&'"!**"!%#($)'#*(!$$'+!'#%""$"$#)))!#"+++%&(!$#%*&(#""*"&++&"%+%*$'$+&+*))(*!##&)+%&%$%&$'*)&$(&!)%"&+)&+)!"!!$"+)$%(+))+!'+*+"!!!"("&%%%+$(%"%+(+$)*')$!*"#**+$"(("*&%)*'+*$$"(%+$)'*")'+&'%&(%!(+*+()($$(+'*!+)($)&%&%"&&&'!*%!"+()*+#'!&*")!+"!#%#"(*+'!%&#"&*!&('"""("'%"%)&"(%#!%"$')+("'#$%!#+'#!$$&($+')&')'")'%)$$')$+*%*$&)"*+#()"#)&&&'(&+"$!$$#'("+%#&)'+$)%"#("+"!($'*'#"))!()$($&$"!(**#&&%%*%((""#"+')%%''(("+(%)(!'&"''%+(&)!"&&&%')(%$!$#+(')#$')+)(&*#&%$("$!('+#&$))()(%*+++&''&"&+&!#+""*&!)+#
@r2870
AACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTNGATGATCGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACANTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAANATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGNAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGTGTTTCTGCGGNAGTTAATCGAACAAGACCCGTTAGTAACTANCGACATCATTACGCANCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGANGCAGGTGAGTAT
+
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
@r2871
TTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATNTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGATCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTA
+
@;EEE.3*6D#D;B;'GC928F;7//2D.:;&D@4('%(%6?!&!%'D$.H21/,/55C3=1*;))=?>$1)!HA8&.@"0'#G7+$+1,DB5&-?FE=4;!A?-,5E+)#,,3&8?A?;(26"2G29:>,A:B6$:0@%5!#6:79??+?%D@B,/#39#3G-2+6.7H'5)A1,3-@'9;&%:>D1EF0'$CE-?)#E+EF,D?=22*>#(/B8?CF&=-18;:=DE%@1.$9%F!;#*$-7H;F">F#;A>0A@.E@=41E*H?1G<<7+1/E1,36D):)G8=%-$FD.D;#0:78D805?4+>(%G8,C<<@G.4H1+5.#>2="AH<G,1F+&
@r2872
GCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATT
+
30<62?G-3G';;";#D88)!?3D@%H#+"FD.;,06(9E6>?$@$E
@r2873
TTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCNGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGANGAAATAAGAGTAGCCTTTGCCTCGCTATACA
+
B6G%#,&";>A@+>+C1&*#*:CH1:-0#3-)!598DG)#0DE0A?30$G!9@7#&0C'E0/'4$$(D?)29#*&%=>E0B.E+ABB1#)87!*AEE<:@7$77<1C%:%5H(BBG,G*)#7&3"A/007FC"E1"&E1BC%'?-EH@)F:7""B?C!A!!.HD158#.1/.+D@%'%"'&?(F9F5!$:-)66&+%;=9F59.%H,6G;#%!5&1@$:3;D?(7<:EA(@&A;7.9B6&D09&4(/"C<D8B58C0F6F)/(9+.D'1%(0/$<68&:.C@0/)'2#E6=?7F1$F63;5:8:0,@%D.3+,'-FC'6%6?+1=3B:66E!1A0&9.H(G.6)6?7$45?D/8%A"%+H%C+C=90D-"F,-C6.:;8D7/+G+GC0=!F/):-)<-$=%3C#?'@$77+.7:#4*@BDG#!";#H,25,4</>:)$'"E@"$))H$?65(>").'02G((92(A&6;?!A*B#(>&8/,/%6(/=#6>-+E>H4;25C"*#59/4F'579?#2=@':08A0,()H@(@$GD03"D?!;?2##-9$5EF3.$)?1/:-0E0H<G"CH(,.>,40(#+<243(@D
@r2874
TCACATTCAAATTTNTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACATATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGNCTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAANCACTATGAACAATTGAGTCA
+
E-.+!(/2$%7CE"?<*8>D4(H7?08/4974AH7@2=:!8/'F-A*;H??;1E:=%-0($;(9DG21,/;0-'3*)AB&D,)'>/#D:7C&"+/'/:0D+$2/,:/G8-:&26$A;.HC>G+&77:/34FB4(3;.=<@=(.=A$$,,7,/2!3*?;B$G%C$<+"88>8HEA"19?AA)0#>065!($;C"481<H(+(</B*F?A5/2=:+F-%H>F?!53+)06HE);-'&4B796C&6:D0>;&D'+<(E#7=@.5EH!-HH5)AA/'0+6-;3E*"5B.52@3<BA==2',7E7(;*>)0AC>1;?3?,*-5EH-0:@7$)-@A*BFHH166&=,9(24"='741=G%:4)&0:AB%:6&,4)!G/<E*;;56H3./$H=+#(%$*!($B5F7<$5%0DE=0-5E
@r2875
CGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTNAGGTCTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGANGT
+
9$)-D<!GD@<<?C9@/8C"&+'3&#%*>H;8D1GDE-!(D%>:?A2G73="HH147BA</@6'86E$5<@1<6);%B5%@=-&B'.8EA33)&4:44B#E@A%?/39+@<84F0-5E-)$!D4:()"8513&B8C11D.$;D9.?8H/#
@r2876
CGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGNCNTTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTNTCTCGNTNCCACTATGGTGCTCGGTGGTGTGNCGCAGATGCTGGCACCGAAAGCC
+
E-!;DBA@3F9=$>BF<&80A6!26H,CC/$>3,AG@1@D$G*F3+'@+1-@,2@&HC)*-,:3/+?,%99(=A')1?&+)>"9:G-?;/=7>A>A2*<$,(5)6%E,(:)9:>E#%F&,:%H&.!H37@">F)%9C6?B50&D$?#/ED2>B=(8(%+DH2G:BH=D*+C@,D+F#,B#"F=+.&9+H<@FC=C#7?;2;A1*.)#04-F=B*86@=;>8G?7)=+7),9(=EB,%>:?-8'CH'#'F19((4.)F/.!=0C,2@
@r2877
GNNCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCANCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTGGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAA
+
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
@r2878
AGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGNATGCCGCAGAAATGGACATGGATACCCCGTGAGTTCCCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTNGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAA
+
@/'GB;5=1CGF,8(&:A%D,#7@E8!9(0#2'$5&5!--="'3%B,+G?:931!!5&;,55(6,1$6$=+,4:#/;E440+H9C885>%&FG/?**(<5$#D8E1*D90<6$=4#)!6CA/C)5)/$A'4H&D@=7E2E3A&+G?B6;"=:$<$70=:08BHH=&B3+056#)'B3#1('60@1828%'#2:5*11:2-(3+2F#6%@F=0<,8/7
@r2879
AAGTCANCNNCAACCGGCAGGNTGAGATTTTCGGTGCCAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGTAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCGAGC
+
$%**%#%'#!%#(#!")$#*((%$$)+'(%'&***"*$++$+"!"&''$'+&&%'(%%%$)$('(&&*"+!*(*''+&+'"&$*+!#)(+'&%'$&""!+))%&*(&'#"+$)(')()+%("#&%)*#*&!&$%&(('&'&$)&"#)*$!+''))%+*$%**(((*!!#)*##**+*!)+)%%&))#("!#"&**$"#!&&%""$)##(+$!'$((+#'!%!!%%&#")*'
@r2880
GGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCNACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGNAGGC
+
C.'@!"H84%6D3#5""6#/=">1);3./)F9&/F9,DH/"?:5",*(6=6?"#G"813.FG?7.2&AHF@>E2/#>8/F0D"&#4D*,$9&F(8E?:&9,/"$!HE<118+4>':66/,'40"?7"-BB=-G/6#*((A;G"6D<+,D8;,*!"?F.B=4$<E&1)9D(16E%+;F/!:@B=A?/$D6.H@<>29E+=#)'486$54A*C9F&@$.(?FG84-D'28/":<01?&,D$=4GDB1-7>;!(10.*$:18/01$7,@<HD&"1A#=D)7*#=H8C92:=,4C<#GDBE7=<*H:?%(G(10%'/)$;3).@;06"=)0%69$$),83GB2D182(,<;?8;7,ED>12):25D$86??1-9'%AB1:=>62F)@&*!<E7='0B/E#$;9#!BE76):C!-!<:EDE#/&9/>
@r2881
GTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTA
+
"(+$#("!%"*+!%"!"'*"!"(%"#")'##"#+(%'*)*$'#"'*+$*#*+!#!('')$)%&!*+%(++#*+)+)($$#)'#$%*#!!)+('
@r2882
ACCGTGCCACTCTGTTCGCCNTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACANGCTGCACGGCGGTGATGGCATATGTGCCGTCGTCGTTCTCACGAATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCNATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCNGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACACCGCCCGGTACATGGCGAAGCCCTTC
+
D)E,53>>87!7(!=!"'!0-,!HB7D+:FG>F9/6.'$A6?%&D8:C(<$-A(<C?#)B*%>.H<3<:??80")&26=D<)9F)$+<$1;*.)6,7<6F(B?(;/6/BDD@+"2:G4@H301D$85/A>70F4FHADEB>C10$9@;!+3E47$1(/F-!*D.0A!A<C14AG+0)6"84.+A'A@D,3='+*%@5/H*'4'04FD@3GB.#FG:@<"C4%7%21:,=F#*27"+!/A%@=%?9!(/@-)D#%%!)G)".(<4/$4<,!9/!;59;(C$:#C!*H@$:'.3$17--A%27@69*F91$<4'E>D6.(5-6>6=,58)-2=3"7825,82;%$$57*F>/'/3F2H@D;"<'?$821$$.>:DGG)@58H3+"?;3F:;86C=7.FG'4-)!2@5"@5">6G/H@D-)GGF(3&GD@E5<"#)B
@r2883
GTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCANAGATCCACCCCGTAAATCCAGTCTGTGNTTGTCAAGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTNTTGCTTGTTACGGTTNANTTCGANTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCNCACACATGTCGNGGTGGTTACGTCCGTCACGTTCNCGCATCAGGNGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCA
+
0%8"1'/+!D?$G>H>!;<A?0@:38@)37<.8G3,F1E@6E3*C0+<G5AE9@6'7#0,A?C07>H6*F0%GH4::"<#GA;%F/%DDH;C>%$2A44E$A@32;(G;B"+",&8:9>H-9;'.*78)=6!D(->",3&!!85/:6=?@($!D'G&<*$E,1#F'3;*-$A"10;$;EB%7,B550*G>%B+#5A!?#.#@E90,8%'&6%E!2+*<G+%.E/;>!H=66$?D=HA@82:+'DF0#41E=(H*3@.68*'*1?-?HA5<!0E)#&B+!2(97H+/9-+*.=.#$+(0*:.<+33%"2?5E>+=-A)18<C==#EE3
@r2884
TGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCGCCTTGCGCTNATGCTCTGTTACAGGTCACTAATACCATCTAANTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATNCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTAT
+
D-'9(&3")5**6?%DH=@!>5$>E(7;(8/,0D8D*"EF=#3)'(?1C%H2HE534*<6E8$?>1F(+68?%6%>F",,&@B>.@'A4!4C<>F9DE;=)%BAF.+H+.'5B511D+?G8?140#7HB<-6&,A!'4&G/+-?6A4E96.34B>B8AE!>E@D.0*'C7)<=@>:08*#8F$G7%+3&3H/=;%78#FF5A"@3-H;95<;E9@>%&,<!6>G/9'"'0
@r2885
GCAGAAACTGCCTGCATCTGTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATNCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGGCATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACANCGCCATGTTTACCAGTCCCGGNATTTGTGAGAGATAGACTTTCTCCGNGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAA
+
?D1>81&1??%"FC"3.@)?&)&4%AB2##F*H5'?&F1!<?-A":(.)%#>E5:*:1B%A9D")(@F6.@''9-<*=DE7!&)1/B=<"3=F,!G<47AA(H6?GD!+/11).;,13)3+&H&?7-$4)'&-:@85F89$9H%*1A@-!<.@-A8C?)8>A8/4E0;H06'>$C.8F=@"D5(4?7(H@9;(,B+2:CD:;+:4<5,0**5E*(B(<132B9+D39)E3="=>-40;%H74+B-#&&F+5&@F920:3*$,;H,&FA=.($'H1.(*-F)6?'/*E8B5#G5532$G:5D58=$D3D+.:3?D/:;"D+B;!((-?E'C7'5'6'38(</*+4$1&,FG5@
@r2886
TCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGACTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAG
+
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
@r2887
GTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATNATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGC
+
5.9<CB?'G'*#,HH@H:#B7H=-0=+D-;G*8+*CHAEG36=!/),%"*%!54>!8$GG+$F021BB-A9C"$170,(%2/5?/<C!%&40?)E'")=)$=C'HA18/+#<*?F/(A&><,C@34;%=7194$/5"D50E+<25=#378$39%32)G1-%$.D-1.2(?@<+)&+%378>,#E92+A2%4
@r2888
AATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGNAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCNGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATANCCGGATGCGCAGGATGACGCCGGTCAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGANACAGTGCTACCCGAACACGNCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGC
+
C19G:2>B,60*6&,A=5;8,0)<FEF,+%;C;5%F;EG+/A83:044!E98--.BH*!D09G;:D("F6*H<4@;1:B(32.7&F@5<H&)FE,&H"(A4,6FD612088-65'966<B,52/6D&-H?@'2F#*DD12+<74,2<=-:E"+*3/14BA96,??0E(,E+8D'89+?-??%+F*-;5$''6DD()(G=6%<6FH%F)A9-F90/G1@!AC;&=3?0-B:!'9@+<$B"1C.*BC*%F)G9C@(+$(7(E@+A*5@%!**C/<';*E/H/<#'>CDA;H;<?1G=B(F()$
@r2889
GCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGNCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGC
+
CF-+.('%3'1:;$:C<3<)C9E>-8A-%B6,>/-6?:(7.0-F#9(B$;*$$;@?7!72(F3:72&2@?F8H+*8D$%#.7,>=0032$F+8!$3;+A4%(8#C,0GD1(29.
@r2890
TGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTC
+
BD.:$(*5!=7D!+3D09,93;1)@"@(@.7,?;$!)97BB94'7$)'@'-799G/2!35B8-7$.
@r2891
TGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACA
+
E!A,!C)+@%?='!@?BGA<%''+$EC/@C8E.7EE&!-6-<#7#BA.FH@G52A?-6CH#:*/.,4?1%&>/?>.8+$@ACF
@r2892
CTGATGTGNTGTCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCGCGAACTCAGCCAGAACGACAAACAAAAGGCTATNAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGNAAGTGNTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATNGNCAAAACNGAGCTGTGGGGGAGAGTTGTCGAGAAA
+
!+!#'""+!+))&%("''!"*)%'%*!$$#*!!+%(%'+$%$&"#$$'%&+%*'$($!!!+#()'*+###!#*!)+$&)(((&($#"#"&"%&"!!&"'%("$)$%()$*$&"#''%%+"%%$*%"$)!(!+%+#&(+!%*++)(!&')!&'*"#**!)()%"&%'"'(*$#$%$$#''#)'$##"&+'($)$(%*&#++(&%''&+'+"$(*')'$#&#!($++'&*"$"(#$()!(+(*%()"&+('!&#(!&*)+%!)#'"***'&$#""*+"$!&+"!##")&'*'$!$"'$(%%*$+%#)!)#'("(%#""(%!&#+(%"$&)+*"(
@r2893
GCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGA
+
7!B:5C<0@),9-C'!2A<9/93$8B43G#+-HDAD2"/.<BBD.-&4*'?03C/98&8H3G6+455"(;BB(E+E79?7&96%,7:(>/G0?&A?1>/
@r2894
GTGGAAAACGGAGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGNACCTATGGCTGCATTCAGGATGCGGNCGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCNTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGC
+
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
@r2895
CGNNATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGACAATGCATGACGACTGGGGATTTNACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCNAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCANAACTCAACGAGCAGCGTGAGTATAACGAAGGTGTTATCTCGNATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTAGGGGGTTGGAGGTCAATGGGTTGAGGATGCAGGTGAGTATCTGCATATGNTGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTNTAAA
+
&'##)++)+%*+&*(()#'!+'!+'&!!(%$#**%*((*$)!"%&%)!+&%&&!+!(%!*"%!"#!)+$'#)&''*!*!()!"'""&!#%+*')''!!"*)#*&!"%++"+!)%%!%&+*!)#!!*&&"%'"'$$*)#!%!"!)+&#+"%(*"$+*&+$+(+&*&#&&"'#'#&+$)#!('+%#(%!&&*!"'("%#)$"(+(!#%&")*&"")%!*(!#'#"))#&$%&'&+&&"*!'%!%$*()))%*%'$!&+&#!"%$$'(&)#''(($(+$+((*'(**'$&'(!#!''*'&'#$#")(&&#%+#"#)+!+&&&)'%'++$()!"!&)#)+!#(&%"%()(!#+&*)$#)#%%+)"*!!*&)'#%")#$)'*)(*%&$$##*%("(#(#$"!!$($%*$#!%#+*&!%)()"$#'##$#)*%"(($!!#&"'"(!*#'+#)%#%+)(&("+#'(****%+"&+($&*"&)#+'%$"'"*$!)+*'&('!'$"!)($"&%!!+&'%!)$(*#'+$)&!%&&()"#'#(%#'*)$*$"+)&"))!)+((*!#!%&
@r2896
GAGTNANTAAATGCCCNGNGTTTGGCGGCAANCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGNGGCCANTACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATNTTGCCTTTGAACAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGNATGCCGATTTGCCAACGGTGTTCACACTNCGGANATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCNGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGNGGCGGGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTCCCCACGCTTTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATAT
+
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
@r2897
AAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTNACAGGAGNATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGANTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTANTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGNATCATAGCTGGCAACTAATNCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAA
+
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
@r2898
GCCCATANCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATG
+
9$FAB&F?=->5-&$+G#?/1'($5')=A.B88=D9EE7A&0-)+4/(!(A%E>=@G3)=$4C5
@r2899
TACTCCATAACAGGGACAGCAGGCCTCTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCNTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTNCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGNAACAGTTTTTCTNCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTNGNCGGAAGCCACGTCATAG
+
+B,:.02$=$1.8A,("-3A;-9*-%%D;<31=!4%DF??=>G5A9E-%D3%%0C5.1$F"//6BA%),$8@");C(C4,+$GD-.?=(H294<)#:D.+E(+##<0-B'3DCA/H*<AA>/49C%"9!(29DF5@>$&.$&6*$(%"2<5D4AE(-H@1>(&A$37>>CB:-23G0'@1')'#D=7C4405&?4<E'.A#!G<GDFC)-6F.1EDF+B3*:?B.#D9+/G/=91;55#.-621!E7A,+)1)FD+&-D5##2E?G%(0@".E&"<?@6&',&=#GD<5$F$"67=2FG6*@"0F<+?3(7(*B"DD52C>EG!*:F0>#0;C3?BE($0!66F0!BA!@F/!0HF7
@r2900
GTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGGCGCAGGTACCGCAGGTAGCGCAGA
+
H,(DD*C'%7H36*>D#!D;B!D?,:/+1:?*H,*#H+28!-E@E-7>G)@E$:0?EA<E88H"DF8;6@!)+/233$)<&&F78D+153+++)5*8+=1,6>6D5A4)&0803?75>B%!H9-)B&%)?,G+*.>H<'7$#C!B"G>76"71C!%/'%4/2$>G4E/$C367%E35
@r2901
NTNAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTNGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCCTGGGGAGGNCGATCCGGCGTCNGTATCGTTCCGGATTGCNGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGANAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGNGTTATCTNGGTACGGNGCTGTACTGGATAGCNGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGG
+
")+##$"'%%#"&$#'+!'&(%#(*(!'(++!#$#)#)'*)!%"))&&!+'#("$""$((&)#&**''!%%#$'''%&*($"#$"$+%%'"'!(#&'*++(!*#&+$+"(&$#&!!(%(+&"+#()+!$#('&+'+$($("+)$+')(&"*$!!'($+%##+'*)!)*%%$$+($%'&+'+##($%#+!(+%'"'#$"))%("((!$!$$)+')$"%*!(%"#'$$%('%%+"(*+"%%!+(#%(*+!$))(!"*+*&&'%"#+!"$%)(%!$)&'%'&#"$()%"''(&+$"&'$#!!$#*')()+*(%+'&'(%+%)##))!"'*###$(#+#"!&+''&!$(&*#'%!#"#&"'%#&(&!(&&++''*&!'++%*!%(%&'$+*$%!%##!"#()%*!##%""((
@r2902
CAAAGAGGCAATTATNCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGCCNGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGACGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACNGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCNATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTNGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAATCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGTACGCAACCGCA
+
5&,HHG-:/4A'&&">6?!F+<,-9B#C.3$@:9#A@B3>@<584056*=78?HD.3&>4)$A37;)16A337C@>*;7@+;91"11-&&C8.8#A6:0D!&!FD0@C4;.0.E@*-&6$>:+10<H+31(<+%'?0!EB;G/=,E-/#,*'G/1H7F$:7)G=:9"8),E3!F:-=2)*(4)B=/%%FA7''$B=36'?>4(D>=C>")$7B5+?9&8")1+&$B*)'%D-A7>!B$:D6C:0,*!%3D6!C(5)1E;>B&8G059D/B><<&9,*56H&<?4A+>,@3A26+!5%@>)8;4B>76C&976?A:'!@A?H2G(>H'*$(*B81H,/7>,H2-)/?*=%@,?%F"H8C4A3;,#7.8<7<0H&)!B35&4@$)6%45@5,;".@,2;0%4@5?3@$$?6=";"E$>C8(?074&8GB#=29H&9.,',!F)?'7/.&$0-DD'86HF0;*&D6)H&-*/GCC+"!,C
@r2903
GCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGTCTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGNAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGNAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAAT
+
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
@r2904
GGTNATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTNCATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATATTGGTTTATNGGAGTAGATGCTTGCTTTTCTGAGCCANAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAANTATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGATAACCGTCCTTTCNAAAAGTNGTTTCTGCAAGCTTGNCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTNAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTC
+
()#!)+&!"%%'"*'%!(#*&''#!&!!))&+()'*""+#"'+')()(!()!+&&"(%*"")"*"(+%)&'*$"$+&!!&(!(&*%!!''%'')'"$!*+&+'+#+#+%%&(%!#$#!*'!!)&$+$("*$'*'*%%&&$&*#(&"$%$%!'##('$*&"!'"'!)+*'$!*%)$&$(+)+*!%()%"$"!!)#(%$&*'+&)%%**)!*(+$)*%("((*!+)*#'+%+(&#%"*&%#'$)*'%$%"'"(%#$*)'+)%!(%$$$*$##*&)$&%&*#'+!$()*$&!%*'(%%&*+)&+%*&*(*#'$)%#*+%)%)!"#%)%'""!$+'+()+&()"%)+#(#&(()$(()"&&'+##!&*")(#)#)#$!"!(+*!!")")*%('++()$&$+!'*$#**!*"#*#&"%"'#!*+$'"*#(%*&"&""'*(+&!#$)"%(+(+($!&#'"&)#!")*!!)&"$+!&(($%+)*$$$#$$*&"&&(()*'$&"*$&('"'*'&%#)#'"%&""(%&&)'#!+#%$&'(&"'"$'"(*%+#%!*%()%&*)(*'")(&*"&&&'"!&"&'+"$$"*')*%
@r2905
GAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGANATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTNACGTCCACACGGCATTCGGCAGATAT
+
%(+$&'+()"+'$)&$((**("+*%)&!+&(+#+(')!#*#'&!(#*+)+))!'$#&($*#!'$''+%%$)(('!))#)($#*$+&"#$+&$+#%'!($(+""*'
@r2906
NCGNAAGCGGTTANCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTNATACAGGGCTAGATAANCATTTTNTGAATACATTTTCGCGATACCGTCCAGCGACNTTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGNATCCCGTNATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGNAGGCAATTCCGATTTTTTGCGTTGATTTTTNAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGGTATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCNGTGCANAACGCGCCGCCGACGTATGGAGTGCCATAT
+
#&'$#%'&')(&%$+&"!$!!#&#&%#)(&&**(%$#!&++!'#*$*%!$%+"*"!%"!$%*$#""'%!+!"!'*)#"*!!#*($+#&!!$#'(*%'#"!&**%++&"))&$%'$'**!!%(+'"%(!#!')')#"%*(%!!*"&!+)*+!++!($#$%"!!$*%#($+'+''$(&#(#$$&(!%*+&'%&'*'&&&#!&$$+#!&"#%%!#)*$!)+)#%#%)$*""$!*)"+)()**&(&*(%%#'(%'$(&$(*(!*'*!&$&()+$%(*)##$(#")$%(#'$+)")"('+)#&#&**%+#!*&)(#''"("'"$)$%#%)'&%&#*&%*+"!"#(*!##%%'$*#"'&!'))(##"))'!%"*"#)*!'#)$!+%$(&&&++&&$++*(#(*("%($$+'"+!!)+"&'&"!&)*!"$(*#*+)+%!%$$&(&"#"#%+''%$'&)%&&#$)+'$#"")&#%#)(*"$"*#""*$)&+&%)+!*)%)())"*&)(!%"'$&%$*$(*&""+*"()*+!!*!'#!+&)&$'+!#+(""$(+&&)$''&*)!!##*#%)#"'%!)*&#"$+(+$((+&"#''%(+%)"+'%#$#*%+*(&"*)%"'!*&$')"!!#)
@r2907
AGNAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATNACGCGACAGGAAGAAATTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGACAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAG
+
***+)))'#)!())""#$"($!#$!"#!(%)$+)#(#%!'!))#"#($"'&(&*+#%')(!%+")"&"!(*$%""&'"!#)&$#!'+%&"$#$(&%"&%)#&&(+)*%!'#$+'$*!'*&#*"$!%%+!(+(+!!$)*('($)$'+%#$%($+(#*)&*&*%*(&'++(!('*')&!(+*")*%"("&+$
@r2908
TGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGNGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCC
+
2*#C"9=9362C6"A3.'@>C&%8%;;)!<9.0.%)8"8"(H7?<B+.FB'->22964<A+$@DD#!F78,.69<*5!.@'5?5!B30B-(#,-*4D>2;!>D*$.;>).0!D*=>.!=B9,<7)E5?)919A))=:3.HC,4%@;"C/%E+3G+'59D$;H(?7$#"B:94+#1%B/2755&(55H86AA,0!E2H,(<2D-.B13;!/AG860((;<95!9;BH13$>E*E"'D*E+-!"82
@r2909
CGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTNCTGTGAGCCATCATGACGCNGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACNGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGG
+
*<(99A=#4>5#//EB'&-E>33*=&*<5+="B"!E;$0*,=A"";%<3/,:1)*<45%3B243%?5%D.CAD<5D$09)'&">(*8GF),';9<%8F&.)6(A/G@<A7(7>A*A1FH,/>A*2*#(F+G5/<D(6;EG":*<8&H6-346#62G!HD1H$:/A
@r2910
ACAAATTCTCTCATGCAAAAAATATGTATAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCNGAAGTTCACCAGCCAGCCGCAGCACTTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAG
+
/;1<:9G/9D49?;3(EDF&&2&(8@D0=.&-G*>+<.5+),7#E,BE#/$$>"6";$4/;&'F"=2@7G;(3.9@CH%>6"(9%B'"F7>43G4G?@;8AB>F+!1AB'0H)B18';:%738$%<9B18.$=,DB(0C#1'6C=%>@$-D%
@r2911
TATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGANTTGAATGACTTCCCCAATTATTGGAAAAGAGTTAT
+
:9DH@;6+>11:AE,G+@D,;5&=71<#<3H1GC?+03G0$"3!372#'.1DC2HAC,-9E313?B#AD7<=+<+A%-G*D(:H#%*-!/-&@>5.#A8'(F$5D/'A4!8>B-.@<7*AC($3,!,A&;27B"=->0/;)(F92,9$8;H#,%:?F=+:<%E&>6$;C)+#@$>#?)(A@H
@r2912
GTNTNATTTATANGNNNAATCTAATTTAATATATTGATATTTATATCAAGTTTCTGGTTCAGCTTTTTTATACTNACTTGGCATTATAAAAAACCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATNAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACNGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACNTNTCGCTTATCTGCTTCTCATAGNGTCTTGCAGACAAACTGCG
+
%'%"&$&)"#')")#!#+(('($++&$)#$&+#*'"!!!+)%*&&!+$&)#''""%"($))"+"+*')""%&!'"!&*"&)++!""&))*+'!%#(!$)*!%&$#(!++$&'"*#$!+#&+$""+$##+&)$)#*$!!$+")%"+%(!)"(#!)+%$%&'&%)'&*)%%"#($*'!%$$"&&+""+#+&$!$("(!*")%$%+&$&!&'+##"&*!""'$)()$#(($)*!#*'($#*&"&'&%&#$"'")&&)'')!)'((&")"*+(#(!*%%(!%&"*)'$)+!#*#
@r2913
GGGATTAACGTGAAGTACCGTTATGAGCNGACGGACAGTGTGGGGGTGATGGCTTCCCNGGGGTTCGCCGCGTCGAAAAAGAGCTGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGCCCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGNCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAACACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAANTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACA
+
%74$:?&3*DH,9<'2G.>%?&:@&0#E>26@B"!4*"8,G=04'5):0*#":G-)24+</--?=#!)D$@>7?*@%,85D2$41C0G6#2H!!(F'59,$B2703.9/6=-A)H**?.&/6>B&C4)AC9DC/&;46E4#.)8-,F"E/A@H#0'H;2>C!FA"CCE/+=>"1)*8,#78>!)8!+?);%$*(%8--?B0A"43A8<"B=&1D/3;3>939%-D=3+<F41=7>C9:8-G5<4B22,<-?"?E&$!B6G;.HA&51AE<(B'&C0E)E'%/6*HG0-0($%B2A,">5G&@E#-(A2'?#<CEC=*8C*25+-)#@D<C4H@#2:!/937#%+F:7
@r2914
TATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCT
+
CH/F"!<.6F;?0(@8?"ADF5=H)%$7@.)H&$5?7++&2.
@r2915
NCCGAAAGGGATGCTGAAATTGAGAACGAANAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTNAGTACGAACGCCATCGACTTACGCG
+
*#%+$!('$)#$++('&*&+%%+"+&$*%*#)(&#%*"#'!&'%%)!%*()$$)*'&)''&$&$'&%'""#*"(%%%('')+'&'"$""+&%'"*!$#"$%+*)!+&$!"%+&"*$$')"!#
@r2916
NNGAGANCNCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTNTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTCCTTCGTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGA
+
"!#("%(*!('*+%#$%#&+&+&&!$$'$"*%'%%#$()'&"*#%)"((($!!'&"'+**!)(#)')!)*#(%)*')%&+*"*+#&+(%*"!*$"%(*%!%$#+!&""+'*+##&%!!%*&)($&+'%#'%'('&"*$'#*"'&%$!+('(!"+!#'#)*+!"(!+'"&&"()(&!()%")+$""%*!*$$)+)%+*'$!(%$'+)%*+#(%$$%"#'$#!)('!+*("')'"#!&%!#((()!%&"(%+$+)("&&%%*%(%)%$#&*!
@r2917
GCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTNAGGTTAACAGGCTGCGGCATATTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAANGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGNGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCC
+
#=G@=.%C*9(H@*CBC,/=<%87=$2,@68/3=>5$6>.8-.A:%G.+GC:7;E5BD=D!+3;/,=&:$9G5)&0=8)?(/BFB)H@-2H28?5162A&1/8:CG2:>.0%!$EGH9.B,=='):'!*%%;4&G1-?(1#>;7B(.7"H>'E=?/H7:@5E+>E-$((#34/%<C@0F4146,&16!*30G61@/:3?7(*0(7-<#%6B')B)B+<G)>DA'>:?:0GHE"2643<G59*!34#24&@*,!,@/:G#B.?4;),'>B*.5!38BEA,$*?;!%<$A@;H(A(6"9:;E&/"!64?.)"A6,2%-4"F&,14BFG@:"1)/777C6G9,-0EE:1;G1"*5/<E;E3$;!24)DEF,)D<8H8=,69>E/@G!9#'C8)0"',3(;5FH0%(6.BBBEB7<!92D.03=;1B%B%6&"0?(69#?B(4<D<%*(E2*1C9$F"@+932G"B:5<*?/H=4F-D(E
@r2918
GAGTTGATCGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATANATTATTCCCTATTGAGGATATTTAATGGACTGAATTAGTTGCCAGCTATGATCCACATAATATTGAGATAAAGCCAAGGCCAATATCTANGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCNTCCACTGCATGTTATGGCGCGTTCGCCAGGCTTGCTGTACCATGTGNGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGT
+
)$D;H-?*(+.8H?8+.GF%5&1F9/>A!1<.3E(H#=:7=)C=45!2!6#)H@<,H>*CG("?"%%(#E(,23<=3'4(#;A.531#$/%";(HE7;:2F!>*+)$0@$'&25*4/:856(A-8=E37-$-&8F?*.".$5B2"C5?1&9482"/&$)-$0H#:*6"G0<5&'GC+75(>$AB$E,A&60&='!B8&.>?18,.-7FB&$==D+?9/0$@($%!6DBB95G%%+':B"->;A08?+8@:=(.76&)2%/@?F(F!4D:69F(A<:21*6"E)%*::'6:
@r2919
ANCATCATNACGCAGAGCATCATTTTCANCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCANTTCTCTGGCATTTTTGTCGCGCTAGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATNAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATAACACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGNTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGTGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTNAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTANTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGNTAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACNCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTGTTTGAAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCC
+
)"1'@/?8;32A1<-E3D2/%#=.$7,+%$%H(D7F=/2#FE<B)CGA":??C7BH<?D.)H-'*8/E<1.*-(+0+.G!C.DE/FF>5C60)F!;G;HHA(A?=9HE023D#>2"07&85:>+3<3-#-6.,.8G6B=-';C!18D+/;;!%CF7(=+)$&?%?B<&;0-7H889C0E"5@0"0$B!>EH89"5%D.)<-3#?)A?,"@4&2'<E6D."GD247(/%<G@&>"C:5.#8A)9/F!F.!8@00A9-;.G"%&F$<-B0$,"=5E":G!00,=0/&?)CH#:"1BGC9)9&4%?#/6*BB1A#G?'=E#B6H08.8>H.D6#=FBH#6#7!B8009>#&<=C@,14@?$*/3"EB,H264G?+>!,/'F6=,@B@!&44;*=,@$7F=9G;E(.*!<:%<6.=H&?4G5?EFA$&H,?'AB62@%9'@),,D7@1:$>?.95(7F;C1B<!69&0)'7+2"91#3(-&,3E-B-@'>#068B.7F9*3>$$(812<'=-'3)2E8#76D96F!&@1.+:4=4%#0A40=;-29=G%>-F<>6DBE%?#?:=D#!!"$#8>1BA*F*4#5#:5-#1>C$9+>?D-'=6/96?,56C*(EF22G9C>C!75891H@1),8E+(:E215"BA#@$5&&G=E%@8;!#-"*$A=?@,A):6@=@3@*>/*;:66B/@0A#C15)2>?B:0)*1(7'28,HC(/>C4/-13@,<)08'88<*?8E>>)<+*/+7%:+(C@*<C$G=+>71.=.''2:6!C70@#.8"2:)71:#7(<$>><C(759G+!*$;/H7&74@'$7>,F&+/E>D>&-G18:486F;7:@7>:.5B?;D%/253)1<A3.0:!$-$!77G=%@#/H25FH=>;F11"#17@!D@>/$;B&4(=E?G<55%/,DA;1E;(0HC3.6F!*F:7$//,H.&>:E3-.-C,;>>>"32&D%D29.$+8;(0%2-.9:AF87DH'B6AD#B*G0<(
@r2920
TTCCATGAATTGGTANCACCATCGATTGTCCTGGANCTGCTGGATGAACGGNAAAGAAACCAGCAATNCATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGGGNATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCGGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGANGAGTTTCTGCGGCNGTTAATCGAAGAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCNGGATGCAGGTGAGTATCTGCAGATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAANGCTTGTGAAA
+
?;(4F6(<#0D%/@,)78#%;/F4!-6,D9-"D!C965>D=$417-8B3?!!D$;"E<CHH<.C-<@&<4<3>/@%;BHF2'D/"67!"11GG3'(G(7G1*69$G<9(2(C/.8>9+<>8?4)E''*=,HH8<&@5G&9(=F2#!;(.F-560B';@34!7,*>'15#>"'8#294*(=$G39C)>EB$*0!.?0<2<HC:B!$-09.'H700"F%A0>9;(?<5D320#7';?:<:,7,%$C@0:0E5>5.#*H*ADA@;+*::5+H@-7/')F>!657?:D)''H;!=?!92@*.<AAC*1G"<)6>5.:.&D73;D339H=2=%E27E>$-:*216:$H+=?25(9+417FC.<3$#%@>$1A,B@%-&(F$H9CA2D95E<;3H;.9"4+@3E>F'5=F4+C')"0?,!@3FH(6F1'+#FH9#$+0H2&F3*D:1F,?#?A3;;8+3>4%*"%97G"C9FE?2$@#CE3C/F(9DE18-4G&,1!64#79)'2
@r2921
GCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAANGAATGATCCGGCAATGGCGGCAGCCCCCACGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCNATCCGTACCAGATACCAGCCGTCGNTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGTAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGNGTGATTCGGCACTGATGAACCAAAAGAGCACAGCAGCAC
+
#%+"*!)!('#&#()#%"+#&''*)%!&'$*#'##&+!''&%"")'&$)+++#*%"'%$#&($$&'$$%(&'"((&+'($+**&$)$(%$)%$##$"$)"*$#%)'!*')('+!'+)+')%#$#$**+#$)#'$'!+*)&#+$'(+"%'#+#)$%&#**')#"#&!'(!(!$%"%$($+#('+$*!%$+*')(+$()!$)'++!))#*$)#'+#"&%!*'!&*'!!("%"*)**#*((+)(+$))%(&!#%!$$#)!"+"*+*!'(""!&)&)'%%&((#""'%$#$$(&!"$!!(*)"''$!%''+%'&$&'*)"!'!(&"'&"''#+'!(#$"$($(*$+&*#))+##(&#+#%'+%)$#&!')#)"$")&+)"*$%($$&*%%#'*#+#**"+"#%+(##'')&!*!%)*""!)#+)'#$*&*(*"%!(%"*'*+)'$($##"*+!"&*%!)&*()+$+""")$+#%%%$*!)&(#(#$!!+#%(*!'!**(+&''%$"+"!
@r2922
TTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCANCCCNATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATT
+
46929?E,)BE><&!&)(9@A?6%H4DFG-?#"5;(A%2;$)"".)H)95E-3H4D./<2*3.++.!FB67$3((%((:+D;6BA1H>A61E=&&$D">!"0H'#+B8*+#+5*B:0G*2=5*G13$B,5E>2(2(>:5<-A4E=(%'H;/;(7&2"E50&)<@)"@2.$#CBCE=1(!*&)
@r2923
ATCNNGTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCNTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGCCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCNACGCGATACGGAACGA
+
$*'"""**+#$("%*($##)#)%#!)%&$*&($$"(&'%+&!'!""+!"!%+(+'!!(**!')%#!!$')!"(($#"+'*+*+$%**+$%"+%$''))#$%#$%&'##!!*""'"'!())%&'+)#("%*)('&"*"(&*)#$&'$$"*'&%%'!%$#+$"&$$("%+"(%(++$&%$#)"&!('*))!)!++%#!%"!*")'$)&$+$&%'!$+""+")#"*("&!$**(''($)$)+"&'$#&%$&(!+('+"*$&%(('$($'$*&!)''!)(%'*+)#%#"+#)))$%)*+(($&#"+&!)))()')%&$!!!'$('&!*)*%'+%%#+)%$('*(%)*!+%%#!'")&$%&"&#*#$"#""#)%)*++'
@r2924
AACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTNGGTCAANCACCTTGTTTTCCTCGCANGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGNCCTCCAAATATTTCGNATGACTCAGAACAAGAGACGGTATCGAATCTTTTAGCNCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCNAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGNATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCNTGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACNCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCTGAACAGGCATTCNCGTCTGANTATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATNCGGTGAGCGGTATATCCCAGAACTTCACAACTT
+
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
@r2925
ANTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAGA
+
@"!=7!60A6.$;:E<*<BG46)#,:"A-!23>8/9H72G9#>(@.@
@r2926
GCTANACCCTGTGTNCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGNTGTGGACATAG
+
$**((+)&)&&#)*'($$*)($+)&*"+'!+"!*!(#))&!+!#)$#%!&+%%(#!+)('$+*+"%"+#$##"(*+%$
@r2927
AATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTC
+
>966G*HC)8;8C6=H7A.!<.>.)H.'.?E(G0G#$-*"F/&6&;899A63,:"G52!)B@0F*D6/#H:<BG
@r2928
NGACGTGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCNGCGNATGTGGATAAATGGGCGCTATATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGNAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTNTGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACG
+
#*)%'%*%#+%+'!!&'%+"*%'!&"'%$)&$""$&%&##+&)*(+#'+#(#*&'(*#'(#'"'*'+("#)!"&+'$)!!"(*+))$%#$#)+#(*+&%(#*"'(&&!'%(+%!&)('$*("#'('%%#!"*%*&(#+*#(%#(!""&*"%"&$)####+&'*+%)#+$"+$*)**$%+)&&+#%')(''%&)#*#"'*$"+(+"$&&(+#+)+&'#(!+$+((*"%'!&'&#&$+"#"**%#&%%$$&%!&%!*'*)+)"&%)(%"((#!*!!"%$!*%"&&"+%'*"'$##(%*"!!&#*$)(#*++)&!)$%$+))!"$%&+#*')&(#%'+*+'%(&*+"&$)))!&%$%&!*(#)()$)##*#*'#*"!%)#!*$)"*'#('(+((%(''($"$#%)&&%*'&$!%'"!*)"%%$**#%'&)%&+##"*('+)()"#($"$&)&$*$$"!+#*%*('()*"($""$#$'("'#)(&)%(!&($$*$"&)")&%##)')$''$$)+(*&$'+$&+&!$*!+*+'#(!!+##*+%"
@r2929
GATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGNCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCAT
+
A:>?!-9.*A20@G:&#1B8D";GD,&>2)EH<:6;-D2D:,3<?H:9BD2=G5*E;A8:?B%:-+3#$%C2<(7C'3,F@!<*D+-+D2#,8$*2F+0&=<88D3;2'6$+C#'**;+F8E6%7?0EAF!$?==#D;CF2C<$D70!!?-&+;(5)2@>8&:8<)98>,FE13*?%=H8//;.$!/)!87C?>!-!)C;A#>4<756'+D5%3A=29EE<-6F>8#+;06,)3D5GFE!E2!:(G454/C'420D##8!5)9;<-'(%%.6?2A*%=&#+9-<5E9'/DAH$?
@r2930
TGTGGTGAAAAGCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACCAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGG
+
#D?CB872'9,)F$<%C3A$B4"<6=3>5/7=2:D<$*.DF>/B&6"'6/9":A@8<=G8B?/.F61#G$@0@'"%?<3B2&3##A;$,'*D
@r2931
ACCTGCACGGACAGGCCGGTATACGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGCGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTNAGCCATCATGACGCCNATGGAGCCTGTCCGGGCGGTCTGNGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGNCCTGCACTGCAGTTCATGTCGT
+
%03GD'GC/>-?5&/@<3F(&<60?*B9?=3")*D/3AA)!@/5<4GD*:$@"1G125)>FC;=DD(+76;H'?156G)42?=@)*B<56:9*',2,2A!:<7*-FF70"+'1E-!2C#8=#%.;95%'14*'#D5HD),)$40(,,B%C3>9<C7E9'G4A.*E6$:>&D856/,*%70;A3<559&5&(,D4,6:5;A(!*$+$7!&.8097*E>93#HD5.84=6;06,8!2',B?=;+#"G=<F7B0$)#B="C*8CG;5)#;B8A8$&D@CF.8G+.&@5%G#E#HD<CG
@r2932
AACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACNGTCGCTTGGTCAGATCTGCGCCCGAATAANCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCCGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAAC
+
/4F#E!DA8#-3**26>C,"=5#4H":$$;2"A8G4C5,"'+1A@0B&97+.%H"#H5(G(B>H0">1!$$8311:")B5.C+/8HC,7%C<9:7>'-4@BA5'>%>E,C0.;0B?3#=#5'E-/G9(?;=?B0F26'A%E!)*'8*4,@6&/558:<G!AB=.4*G.?1(&B3+510>7>5$>&H<*%76":&:"F8464C;C&!C>1/65*#;/H/+??7#5@028F.)/*A:9>G#7%!CA38!:6>=BF*6"9H'@<<(DC("!3?+*/+5B75!-*'":!/63;B#(E=6?%&%?%6&2A2?G&20.2D=*.A>#,7'(=<:#=4?H7<!;/.=&&//(1>7C99-"G/=?
@r2933
ATNTTTCACCTGATGAAACAAGCNTNTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATANAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGNTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCNGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTANTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAAT
+
$"+!##"(($+')##'#)%($&'!($*#)$'#%$!*+(&))$'*"'*!'+!&+()""'$'###$'*#"#'(*&!!'!#)"$()"%$#)(+'&)'+%(%*%!#!()#&%"%'"$"(""*'&'&""$+)*#%($)&&%+$%*&)%"*'%(!$"(&!)#(!)&($+*')#(&'*(!%*)$%+$+%)%"&!!**("*#!%!+!*$'"#$$&)##('&)$+!'("%!(*"!*"%&%#(&++&()#+%+!'"#'$!)#%*%!&%'!$!%($"$(&&'$"")'$!*&'"++)&&%+!)"*#$#*!*%$*(&*'&($$%$)#*!%)%#'#''!%*)+&#+*'+"$+'##+%")))"((+!+&#'&***"&)(+!")("""(+$%+)+#*+)+'+%')(+&(+))*"&)++!&+""'"(#"!"()!(&*%*"'&!$$)$"%)%'"$#'#%)!%"()#(*$$(*&'#"&%$("'(%&&#'
@r2934
GTGNACAGAGAGGGCAAGTATCGTTTGCTCCGTACTCGTGATAATAATTTTGCACGGTNTCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCTACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACNAAACACCGGATCTGCACAANATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAANGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGNGAAGACGACGCGAAATTCAGCATTTTCACNAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCATCTGCATCCTGAACCCGTTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCA
+
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
@r2935
TCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGNGGTCTGATATCGTAGATCGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAANGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGC
+
5391+@9E02:<%*EC*1/G=@!$&*"/<7B;")<$;1'?E@F8%?><#),/-3A3F*0%#>6@H7%8%"@G#!)'<H6,4#=/"2;4;;#B?78=+-/:$+7/0%H5%"';&1?&0>G$B09=0<DE;1@"@H**,$6,?H$8+=7G*D";F7.D6;/(:*.6"%7</"5,"4<0$6)?BFC)H$/:@03@A@3%!*+,E&,.>,#=>D0+>B1/49),H%(&!-'+HA0#G6&1+</#./-1&=G3!(!2G/3'!!.6H8#/%(
@r2936
GCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCA
+
*4F8&5#).HC:/;0H'/;5E1"),$E$G!?=41&D9()4A9$'56+80=!4G
@r2937
GGTNAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATNTTCCGAGTTTGCTANGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATANGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTCTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTNCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCGGCCTCCAGTTCGCCGGGCA
+
('(!=>/19H3,CB:56&=ED@F**A&>$9'#1=.E6=2;&F925?,F'CA>3#3*,$F",+!1F6BE$"B*5$847)>3)!B4'28.?@H>#'(//F:(378;//@B:E!8D$'>+A6(=,G!B/49EG#.36FCECECA5//BF2E@75@H<<'2+!>(FHDGH$7(4BE!(A3/H;GC9D;826(%"C!=B:/0FF#3EG0==>5A<7)31=H0?HA"HA?15+"?C6(6'B033.!GC?=':'&@5+/HG7>!@-'+-7##5*&F!%B=-/E,#(H*!*389=!'"EE(92@D>@C/:('<%G5EE&D,,8?9?;E<$69&62D2G?C=.!F*16D73<(2)<@=BC20/F"%,5HGA4?4E1G0C144%80H%..5"'<%-9>64*E""$C@-).E4&%A=
@r2938
GTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAANCGATATGTCATNGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGA
+
2G"?"7%@4**,H9%;-/F2<=$A,:$&'/2?9G>$?#<C2D1.!5A%(2%8'1H39%,+6<)F&#<(.&+$'$H#"+A48',C@G>;6H+0"%-7A5%1'%@,;#@,0'5?4B<&0BB"6H)#B55B-6#F*9C)78=3.;?)G"=97-.*&G6:37./?90>%27F75=39$2<9(1?.$0,50G513&"F%5E#()08B>4,53'D2!B5+H5,'*F9HC2'H&8&:@7DE?>7&$#7!<*@"9%#0F8401(F8H:)C,CB#$-GCAB>%9";7G/3GBC-?B>'?7(HH=$4.09'00''C*0$794?41@"H>1#"7''?B2)@),74:=*%6,;%B"E#C9+.
@r2939
CCGCCACGCCGCATCTTGCCGTTTATGACCCGAGGNTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATNGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGNTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTNGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGANTGAAACGCCGATGGTTGTGGCGCAGGGCAACCAGAANTTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATNCTCCGGCCTTTTCCCTGTCACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGNACGCTGAGGGCGGAAAAAATCGTCGGGGA
+
)GC>(H$A8(B$2C*%C>8306G&36H*<4=3:;'0F1-=B@0=4).FFF%@E,3$1B'()63/#7.??<*>CF+E,G<$%.0!%4EC7?HF>4<($"%4(8'(84,2="D>67&F'C4#!+A)!D8F03;.#C#5D&.A$#.3DB%=2!AB)""<7DA#:A+'.'5AA06.=6@-!D!>BF;6:DE*)+7(B=E9FH"C2HC#/.,@@5HC0'"78-CC#)>&"G:1,,8?($&6A29.F$90A*$5+53+/@5/&<0;"F.$/$-716"B"5'.1G+DFBE&##<$2A>;-CD>/B&A494./):3E$(D/1,D)B96D"1C&-8,*?&)H++%*6!776">0+#+H)A!-4/&21+H</F4G*B?@,%7*+/$?C?1:<.%17:'-%&(42!.'79;58ECC76#$B7AEG9867!0@/%93E>>3C14,D,-<!=/G)$4:5&9*8,F>9/C:.=A45!%A+*A#F0G1F.0;>>2>#.%39"G)>5H(?:4GE;,C1+A2B6B@>19+9E>/43G;4BB06$H,F4'7@"+;B/%.FH8E7G*/(5723C=(<)=60/6HE+01<",;+0F>D&<)'+"HF%5@4@(+3@;69(%@@7%"!58+:1);/HG1%5*A=B)0F<%-%>(CA'%A0?*%>H::50,-(A.#).C&"703<2F2)<9?B/0,636$@%'/#:&G4/>9'H!9G0"70&1@@':,9&*G;;-GA/"(161B,7+:B.?3)4F=.+?%':8?%/H@3C:)6#(4-:+$E;1:>*$56%@$B91.'B0.:+>":"@%=G>-.72*30F;+6
@r2940
CCAAAGACGNCAAACATTATGTCGCGGGTATTGGCCTCAGCTTGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATANTCATGAACGACGTGTTCCTG
+
@9D$E@.-140/(EBC)8'4-#!'210;C9B/'#9GE46:'.@4F56H<5651'.E7EG+B'?GHB9$'/")-.&H1.?%):GA,GEF*F2:B+C!;$G&"0F@4E)6+C'B)8;#?>:EC1C=93)003*'EBG$"03,H%8':(,%=6.+>&3%7@H%<)5/(BE""&==%GA<11/D0D
@r2941
TNGTTANCCGTATTTGGGTCGCTGTAGCAGTTATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCGTTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCG
+
(!"*$(!*#**!")'##*#(&$')+$$)%)+'*'#'#%*!&+*&!)+!'$#*")*"!!"**+#+#")+&$%)*##*&((##&#('"#')$+!#%"(+#!'+)%")&$%'&"*#!$###+)+()(%%(*'$+*'%!%"%
@r2942
CACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACNCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTGGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGNAGTCCGTGGCTTTCTATCGGCTTATTAGTACTTGAAACGCNTCTTCAGAAGCGTGAAGAGCTAATCGTTCGGNGATACTATATATGCATTAATANACTATATCGTTTGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGNAAAACTACAATACGATGCCCCGTTAAGTTCAATACGACTAATTTTTAGATGGAAAACGTATGTAATANAGAGTAACTTAAAAGAG
+
,'A5C>1-)@1"/<$;@0>:?HE)C(/E#"<1+2>%B6@&@3C,4*85.4E<H94BF;$:3:76?:G40#H->9+D9#@;>,*E:%$8##?/#/=%G/#)"F2B2(*,'(:>!9&=@4$HG()G9%&&+G=+4+'%<A&2%*C3&=/1H++&C1*/4"'%:7)A)%357'9+7:0-@@<19.D&*BC59(E%<9A9B:5?!>B<"E7=A*%8$:7/4E$$0?*%G46G2<<+BHF9,&4C)-:)>@5)(!5+/G>27<+'?$@23@D&??#HG22!2,=>122,;GG?-$$<9;-9::E$4</!*EA<;"+5-,@(/CG'%:FF?9#,.D$;</9&/128:.=>!?5.;9H0B*8/,?*@7?:,>44.1?.$AE>-A2@!<E1=5'>51(B+%4->"3&!38'>+@9(0!AB/*D>C1;.:>/+3&50!;+9-%-0:#!
@r2943
GATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCC
+
7EF/FH0>(A*F%G>;C*,:9(4,H%=F4@29;'0+E>)2@?;"G#)4;=1'#)B3A/;!,833>FE$2A"$.D<
@r2944
TCATTCGACTCTTTATTTGATGAAGCCAGGAGAATNACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACNATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACAT
+
>-;)%-/*&.@6@@85+'-9;G3.+G176(C-/.&<0HGH!.1B?.#-04)%E@7D;@:GD=29BH.,&@@>%#'')7!/C;?=#,2.!.=B;!?>=6E/,>&:;!<C#:@GE/=384+.(.!=%&***96-2!7&!0@<2!+E3G1H+(??+1);-?A:>GA$BG)'$#B,#?9A.&%)1H?=;'95&0C9595H#<",3*0>&*2EF.#A49-7(;$(@18-:+)!18B:/50)
@r2945
TAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGC
+
3.D#*.D&&C#+@E"F?G4E<3.$32-5&C)&#F5EG'-G@,340HG&&=H8(02*?A"<0&9:!C
@r2946
TAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACNAGGGAAAATC
+
+B?F*&!(-,?0E(%@-%=#;?)HCFF"3B:3!7(+7-8@(>>B'@F7A0<B$#>7?#*8!E-#+2:G7?;:=<>15A2=A$@.64>G5?'<?&'(#E&%
@r2947
GGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACG
+
C0;2595?/E01@G+H:D0H>.2+@7$!$/1(502;<!636&(F=%3"'3==A2,.'7(,#*+826*>#E#)$8,%B4#;>A'"6B-/@!FB;>F)GA,7%-D-#BD*G+B.$A,")"!&E7'
@r2948
ACTCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACANCCCTGANCGACCAGGCGTCTTCGTTCATCTATCGGATNGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTACAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGNAAACGGGTGGCAACAGTACAGAAAGACGGACG
+
#(E(;##05FB?(49?H"08)(#5)@F.@3B)7:(&F;5('8<!6+;FB'&74142#$<<<<=+D2";F@>DB/?*.$+?)8<4"!);1D;$G3@/%A=5!6D!+6/:5/;4&!C"-@:8?B0H5@,=%+F$/@:%-$(>1C,+@$37/8#3#",;("31"2,,>D"">93(G'76%0)!:G;1*(<7*/,/%*9+3A+FFE*D!"E<)78:803<2+&D6#77F.C8?G1@B#*+#&BD3?E88$@1-1+F*@4A#*D&*).76F=958,(G#H-.$@9C(14.73');;+8;2'53$A%?EF,$H9>+4@*D;H382:>-8D8:5>-%1$B&@.&!(E1@A5/29!=$=69#FB--:DB/8#"/G41+<A7B'F%+9%9A>1@9CG:@#,&&:E)$5.0F"D+-H&:B8*)5F'!9!?A6'&?.7C>1)'HDE%5"E*(!67/#.#$CH675)H>4'91D#*.,<%0EB
@r2949
TCAATGTGNGNNTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCANCACCGGAACGATNCAANTCTGCTTT
+
$)()!")*$#%+)(!$%#$"$&+&')!%$(*%$)(!'%"++(''"+&%'%&)+!'%$$)'''"$!(""#!!"$$'
@r2950
TCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCNAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTNACTGTAGCTGCTNAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAA
+
2!E2/+F!/?-:$FAHB)6'C4BA%"!!A-:G%,H#@-0.F(615=1<?F,59-')#!1<D""+C9!9B.A%CC@D67,;G@"8,"5%5?"6#A@,?D7G2+H*8?'&7,G21F!D;2C>4DG"F2+;A@5;80A4)B#*B())3*1:>$+,.-."GD;;@A-E(,0G>;9;,6";>.:7&H<B?.#F3=H5$8:+4*3::%,B//9B'/-8;?>E4,D233:.1!9/0
@r2951
ACGCGCCTATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCANACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTAC
+
%>DBB*+B&)77H*G-?&0D,,@!':,<DH:%;.?7<"85#(0#HA+A;15#+D50<=:2>5B'7:8F0$#.A>#/<HH+B1(:,%/16=-==.2146-H<A-=.H%C'8H5F%7$4&20C-;B,@#*1""7.A00*E7!D%(4/!!%2!?9DHAED&&G)BB"/BC1G3..0188<A2$596/84;=.D+FE!A06"-7!B:8@F'@?6H%D1&4&HF65*1==H*9&GD@G$$H127@&"$H!@)'F6)9%&83E3EC&D,'-(:2(3=H$#E5B->?'0#<:5'30@?>:7?E*&%"$4(+%6.E,5$9%4'"?D?:E--+8=4C-8F0513HH1*8@=C@'H5?39?3,"@,G>"FG9&,9F$0(H'H;
@r2952
GTGATTAACGTTTCCACGCTCTGATAAGCCATCNATCATCATTTGCTCATGGTTTCCACGTACAGCTCCGATCCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCANCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGTCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGCACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTNTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCTATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTNTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGGAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGNTTAATCCAGTAACTGCGGGGCTT
+
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
@r2953
TTCGACCTNCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTTTCACCGAATGTCNCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGCTCGTAAAAAAGCAGAGAGCAAAGGTNGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAANAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGAT
+
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
@r2954
CAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCGCGACAACTCTCCCCCACAGCTCTGTTCTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTNCCGCANAATGCAGCCATACCGAATCCGGCTTGTGATTGNGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTAGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAANTTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCNGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGT
+
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
@r2955
TTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACGTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCNGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCT
+
,7/%'D'D5*$"H$*F.!/!A'8(/"<%6>6':D&#6!-.6958$9*438)@?<E-3;--:0"@&&+8?%E;1-4,#ADAE=A#B*$4/)HE50/-*2'"-+@05<#+.'>?-*1=(24GB:.F)5117*#)?$:*H'5+D<4+%<@!"G0*"5/9%!4&>@'87H5<7-36075"=23-4(F)<D*2>4:62%+:B*5B!1/-3.C7'4;GFF";?CHC@!'%6DE;E9<>3(?;E'8B.6C-;%&>E1&;7-)$69HD-!-F6FH;(E51/8.@6/08$"EH=$4*"A:?+658*>6.GE0(7>"DH</&#=8+5,,<6:@=43>@>*E79B3-E;273")#-:/2):1,)/')B?&3=3-H+',#<,!(:@3=6#.-$)4D((8"$;:
@r2956
ATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGA
+
2%$?F&/44GB.EED#71>6%#=:#'B25/6>*B/))A?;9E=H0>DDF%,?!;4;*1G$=0-4:(C%%$2>(DA":*-/4;?=(H4+DDC3=5'&4'%??:%%$?7(>75+/@C)+##D/AFEB#>;&D*?B'!&.%*:-/2&'!&<#$,&?.!?A85B0C58<&+1%+/C4A!?"/?
@r2957
CTGAAAACCGAATCATTTGGTGACCGTCANGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCNCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAACTTTACTGTGGAAGACGCCATCAGAACCGGCGC
+
'/H!E@'/'07CH382'G<#$D('3?D;B=$*223@=*&&#'&)D#$D<""<%9)A)8G/97'E;/6""14%)<*8:<7>6'8,'-=)*G4FAC);H/=5?7?$."?E*FF$81*H3/$>;/9EH#3.$08"*D<D-9$E(BEA.+--'H;0,
@r2958
AACTNCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTGCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGANGTTCACGCCGT
+
E9,(C4&(85)"?5$5.>./C#>>@71BHH+'14(<$%0)0F489)>@G8@=82C/+'2!0-@(C<,70G54='3<1E/A1=G671:C*!H*"*4/%%E#2(%;272$D<;'H69!(?/86'1*<91BE07E5B?'G/HF2'$0B#((EBH!F,&H<=HD??8!E8E($B2?/BD%10.5),&.=
@r2959
TGAAGANCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGC
+
#$")&'+%!*$"$%$(&#!)%%#"+*#$+#%)&'%*!!"+%&&+**
@r2960
ACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGNAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCG
+
H+9<0)'H6=!!&G*93=)*D/--F370$2$6$</!E(DE&;?(D;4=F43%/&:(>05GC)#!G6>1G*?39+:2/+1!"::.G,?.B@$8??HEG5=/*C;;2(%%A-!C+C!8)8%79%(D9.H@8)3*!/6E,(4>/)*0+$>(GA5B,8C!(@-%+%#0"<C@B'A:</3;/&(D&+HE2(4%<G0A<CD")!@9A+32/9'<7H$!5E&?C1@>0A;&9$:68+(E@%?+?3$31&F?EFE67C&&E%=?#;D
@r2961
TTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGNGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGNGTCCGGAGTTCTGCCTNAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTT
+
41-"":*G3/'-G.?@()H'GE#5,)5/163GD'+G)1?6)?B?;/D4!"EC6H3H;B;EH6"%0;)G><$,BF"!$AH$";;'/H?;%D<%%&G'D*@<-%@F<4,,+4*;8'&$7G59$7$G1@(&7%46>.E4D)/7>#(8$A4$.:9,89>C!;7#)6#$E"E;C+@(+$DF*%D&0":E<:@<H*$;A;1H26+'+;5;A0'0.HA83%,=A84E;A>C.(DF=)%!(!?%7<28*6'23*@0*$;"A/!H35G+59,1?2;B"?=+;!".,?,92H,#4#!DE876",5ECH,C
@r2962
TCTTGGGGCNACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTANGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGATCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCNGCTACANGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATNCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGNATAACCCGGCCTCAGCGCCGGGTTTTCCTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATANAACTCACTAAACANAGCNATTCAGATCTCTCACCTACCAAACAATGCCCCCNTGCNAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGGACATCAGCAGGACGCACTGACCACCATGAAGGNGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGNAGCATTCAAAGCANAAGGCNTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGAC
+
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
@r2963
TGCNCCCNNNNNTACANNCNNNNNGAGCNAAANNNAAGCGGNATGNCNTNTTCGGGGAACNGNNANNNTCTNCNNANNATNGGANNG
+
$#!!"#!###$!$$""#$"#!$!!#"##"#$$$!!"!$!$""!#!""##!!!"$!$$#$#$!"!$$$!!#!""!!$!#!!!$$#"$!
@r2964
GATATGGTAGAGCCGCAGNCACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACCGCTATGTGC
+
;21@?366B+2H1C)7)+$B5!<A-22?CB,<?2%,'C!+7+C"6'2:F2D;-1:D:+:8<2)3H#&/1.=3&,?<H$@5&-:2!2&:(!?=)D<3.D4$/*FD/$%7.9>A8?D1>&6(-9#;F;G%5,<"A.A?<:%1F9)(,@D;-+7>2A:($6G7D#6+GC70H1G?G7(;'@6E)#3&/&E$D1
@r2965
GATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGACTACGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGAGNTGGTACGAGCTAAAAGATTCGATACCGGCTCNTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTACGGGAGGGAAGCTGCA
+
1%HB0,'E;*2,F$."@?;4H*!G%:&D7+4&A/+G6=:C9:%"@#A-:/:)HC=5#@F-B$F3'C<B?E&*@@(056D=,E.D%3.A:%%D35=;6*GF74G#C%;@)&8.G5"?81#.<&0,3(;A.-D1;'*-$G1:B'(H48?F+,G.%%F,@,6%>-B3:<,,,.@;;<F'>-E7+/>E6GG&!<-FF?4.,08%=$)B-!148AB/<>5.;
@r2966
AAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTNGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTNGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGGTCCGTCTGGCTACGTCCTGATGNAGGGGCAGGCGTTTGACAAGTCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTNCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGAC
+
G;6)G%!-E:B:<&C.D*1"#481)/*>1!A.&(;E:1":,4CH50@"B'6H;?<,.=A/*=1%74)88F&+/7@3,,:*$=A?A!#FDGC<87,,'(+7,D">6F?C;#(01@3,BF;>:H27A()6/E.C3>%5?C):((G%%A"F7%@+=85=><:G);D6=*6.,1!+#F'&#/:2BEE.7E#FG>/8+(D/2(+G."&'3&#**82?5862=3%",'(%$%HC2'10:"7":7.EF$&%4:=FE)&/C66:F'73'47)C+E8<FC3,62<2*8<+G0#20(!@G;#46)9#7&4#3862F:F7$;09G<F54BG,G7G">1.<4G&CHD'&/*.D(&4"C)#3;>C7(*?%A2/H@8389?*&697=E@>5@6E:=/0:@=D+17>>HA-EF?37B?:82&'8A<*/AG;?
@r2967
GCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGNCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTGGTTCTTACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTNAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACNTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAANCAGGCTTATCAGCGCGGTACCGGAGAATGGCAGCGTGATTTCACGGTCGAGCGNCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGNCGACGCTGAAATCCACGGTCTGCGTTTACAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGNTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTNGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCA
+
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
@r2968
AATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTNATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGCCTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTNCTAAAAAAGCCGGAGTAGAAGAT
+
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
@r2969
CNNCTACNNNTAAGGCNGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCGAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAG
+
#%&)%%#'##%))+!*$$!"'$'$(*$*$"%*&$)+&#"!**!$$'+*%!'#)!!'$%!$!"%)+&+%)!*$$+#%(%'%&'''&*$)$#$!+"$)(!((%*$&"+%&+*$)('&#$$$'
@r2970
AGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAANATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGTATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCGTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGNAGGTAATGGCGTTATCACGGTAATGNTTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTACAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGNAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGATGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGANAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAANCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACNCCAGCA
+
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
@r2971
ACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGNTTNCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATG
+
3;3%388:C6$@&$;62+*$&F)/:1*,5=;>19.>1%E<5.5<E;)'7/&E21F1DB,4B2EA*HA0B03(3<F5C&G=BC004>+-8'@3=HE!!C-&*!-&>!%1D-8)=C<$6@8(/5;B+--"!09#,0=4-<$9D.2)AA<C>'%4;F*9D#;0$5G8!62%B/*'0B=;.!%@8E,,CD>%;:(<="E6EC7-"+(B!6B+&@F>@'2A+=(2#+8<3,+'17CD<6H62&F<1*70.:=.GA46))7,!D:1$A76/8)E*>0(2?99H2"+>:"=7!-/=/./%:9"8<!--/3'?+.1$/654/)"!F9=6A;!?84AB+2(H&!H-E8+5>!'"=7G01%15):"F"+GF<3<E34D*?>C'B@1,%!A6C)?F#&"A43G0:366$9%5CC5;289<%3<;*B0?51=4'":"!)9.E>H**!>/1@!+&:#*"(B
@r2972
TGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGNTTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTNACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGNCGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTNTCT
+
E#D==*(%"27FB1D%BF?(>4!-?12)43H27F8C3%/#!$56H1=06A#-0?:(E2!$29=?6*0+A,6&8A1AHDF<)G.<6E+!6G>5"H,#D2D5F2;'@&B7A!CCGH3=46AE/;$-@,<BHC8/=+*6-/&5@A'EA$$?!1C2B;/25D18$F(471):>:D9D!,&+H0,?=6<9C"?2>:+37<&5AD82+!%:2'9)E=;->15&G(<EG*+D-BH*-(-E#<0?;#*&$"9$0/"@==H')$/AE7B(4B$GG%++0!++00BGB,B&5C&C;.+<4?:<%)-*9?&4"1/+)"%A.CDD80!@?;C#EC+%;@?2,B?9FFGE=?,<$,
@r2973
TCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCAGTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTA
+
E54<$!F=:?4-E&6+F3=;4$=F*!FE/(+2>F:/"*3)C,H5<>+@;.C-7#(4%@<2;5/5<.1'6GG=3A'H;@!@B<1>79(-6$!C>(7#.9@D#%C9145??FF"A??"G'8G-?'+HE?=4;HC$@!0;&7*'4<F&C0A/8G97@$&$;97">$@?.D5E":H0,HH<9)6.7(:%
@r2974
TCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTACGTTCTGTTCATTACAGAAAAAATAACGTTCTCCACCGANCTCTGTCAGGTCGATTTCCCAGAGCACCACACTGGCCGACTGCTCCGCACGGGNGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCA
+
?&CF?9<--4?:<)!8./8B9<<)7E8H%FGE"%(*/&*9!'24<<2+97&078..94!1'&(+HH%'4(><0C>F2?!'A)FB4$,56G3B>/',*FBG&8*45)*7B91!7.6&-4'8;.E!):!G"27$+4?6#E$$9F//.$/3$)"'D5B"4GE?2E-%2+&!8?@"#7?2=%*B$7GC&>F<$!=4
@r2975
TCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTNGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTNTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATNATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGA
+
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
@r2976
NTGGANNNACNTGGCAGNGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCATCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCNAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGNAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGC
+
$'*"&#!""''!#''%+!+'!*&%(*%$"$&#)%$!"!$$$%*)$&"+"!(%"(%%%+)"%))"%)&)*"+$$'&(%"'!&""+&!!*'$'(&+*(((($()&"&!"*""%'*(')&+(&%$*%'!')%(((#!!')#!$)$'*#'*#&&%$'!")"+$"&!%%*%#)!&#(%#'&&)*!(!"%)(&)%($%)&*"#*$)'))"**#$')&'+$(+(+%(*"$*+##&**'+!&'$!+%*$#($*%*(')$#)#**%)+$(("%%+%#($'&"$%()(*''*+)!$#'*&#)!("#+%%&)"")(&%"'!*(%"%)!!#+*#$'**"'&*&&"!$+*&*"&#+*'&!'%!!#&"##+$!*&&$+%*"'"!*"&&#+%*+()'##&'!)''$&&!"+"##&)!'&$%#+*&&#)(($!(#
@r2977
NGGCGCAGTTNTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAANTCTTTACTGCCGTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTNTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGNACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATTTCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGNCTCTTTCATATACCCGGGAGTGA
+
"*($*+'')*+"((!"#")&''+%'!+$!*"(!"'"(#"!%$*)"'&(!%'+#)%"*"*#("!+*$+*"(+(&'&+#(+*'%+&&+"'!&)!%'++&%!'"$)+#+&+!'#+)!+"'+"+#$$&))%+(')&!&$*#""#($(!$%*&$"#!!#"$*!####"&$%'+%*($++%&'!*%+%!!!$$)*#(%!!$$()%%("'"*&)*%)&!(%#%"++%'&&'$)!'#$$*&!*$!$#(+#+&++)"!!!+$*'!&''&!*)+'%)%*)&#"&+*((#*$+!+'$#$$)*'&)$*('*&*$&%($&#&)&!#*%$('**&*
@r2978
NTNAGNNTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTT
+
'###()&#+&()%#&(#(%+(%%&*#&&)*('$#)&#**('(%+%(+'#
@r2979
GCGGGTATTCCTGCAGTNGNAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGT
+
@>,19?%+4*E%7!(@%+>&F6@,>/1H30C.DE3/&C=&F$A>/2CB&F<0/+=5:@3GA7.B,#?AA<#4#DAC*;0*%<8%(,.<#1!(
@r2980
CAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATG
+
A*B42B*+-*'D(H;B*AH8H)=2D?,"(*@1&#=$8<@:9+)7$&DC(H(6'..>;="2/";E?
@r2981
TATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGNAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCANTGCACTGATGACCTGGAAGAGTTTCTGCGGCAGTTGATCGAACAAGACCCGTTAGTAACTATCGACATCATTACNCATCGCTATTACGGGGTTGGAGGNCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTAC
+
:>7:$@F&:."1(.7H3D)=D6/C@?HDE48-;)0*1E';%F'1"A$G$(*+"9F;>!B32-BF)>&'605:%A-,&&4+@<B;G1EH6>;87B-CG8"4A#GG/@+7/"<@7E7B&H%A33G@85$",C5::E#$)#;09!#)G0C'=5-8?;%>*B16!86"#*/*4H7G<5%HH+#2)C:7G@=.>#F8@BF/.1(HA8A@%$+)A"@;396"$<>#436/&(4"3;8#*C"H**'=7C+(87&AG732=(G1,('#A$<E$C!+-&.=#(,63@/@5;6>FDEG6$)&9"(+"5@);0,%(GE=,F+;()-E09GB2<.%15)+?1/)')D'9F;'-.(A0#?:&=F1206>>F-B7&A87".5$?D,$*(*GG
@r2982
ATTTATGCNAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAA
+
G;AB=!/H(/#!)(E):7GB1H*-4G02A?.@'*/F:(@A15'#%,!6=FB-(DC8*5ACA)$&CH/3"47#9A+22--$'=D,,/@*:"):#&-B=!F1(B/'C?*-.+C+G@'3FH4.--!+
@r2983
GCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCNATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTTCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACT
+
,7E&0!5?&;72%=B5CF$.&FF)>2&%0-"')1:F"64!/)'$@."5!>&>($,4,7DC3'A=?D1"22"18D/?@$;*";C-G'5"5*'&,F'G$H0=%67;-5&+F@?5F"H9:B$)@B7F0"),0?'A"D1F";/@E.A1#:&!@=.B>"1)G!5><;)F'!"B%%/?+!,2?@,G89D>-()C,6&B,.60-"0)'C:.+;;9<'B1@'<@?:D0$',3!@):,+0"9.>FF;5C')>@>$
@r2984
ATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCAC
+
8HA<:7>2-8+"5&>=.<7;+9&!$5(6#B93+::E9>1E*)?.D3'(..9AB:/%209F'H>19BB"D&87>/)C$)H*-6?H@;$,:7A$?+48:%"+$!?H6@((-75%?H75D;G29@B)
@r2985
TGNNGNAGAATAANGCCNNCAGACTGGNGGAGTTTTCGAAAGAGTGGAAGNNTGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGANGAAGGCAANCTAAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGNAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACNTGTTCC
+
&#"()!!$"#)%$%*'!&!*"***'((#'+"#'&+!++$*"#*(!"*%"%+!(##$(&+%%$"%!!')!+*&)*#&!+*%!*#!+%$)!+(''#!!*$+&*!#(#(#'%(#"!*!'&+""!*!&'%')+"#%&'&(+"#(%(!&#(("#'$)(+%)()'''$*+)%)"&'&('&'(+!+*#$!'%&*%$$!''"+"%'+'"''##&$+&#&&"&&&#%!)"(##%+!%"!$(#+##(*('*$#&#"+&#($(#'#((#+&$&##$*%+#$*&$'!$$#%
@r2986
CGTGNATAANANNTGGAATCNCGNNCCATATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATC
+
*$"'"*"%)#(#"$%!#)%"**$&")*#$'+")*#)&)#!$!$"!)))%'+&%!#'')&*%'('!%(&*%))!+))&%+)$"(%*$$%'%")%!$*'+&+)&"%"((!($'#
@r2987
ACGGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTNCCACGGCGAAAAATNAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAANTTCCGNTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTNATATGCGAGGCTGGACAATCAAGGGNAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAATCCACATCGTCGTTTGATTACGGGACGAAAACNACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTNTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAA
+
)%"#)#+"%%$)!)*&!(*()+&&("!&%&*)%#%!"'*&%"#(+'+')('"(($((%&'%*%*!))#++!!*'((("$)&++&($+!)))$+*!&$++#)*)+&)'%++!$*%"!!!%*$$'$''+"!)#$#)#")#"'()("#!!&"&#'%!#$'"+((#()'('$+&*)%&(!'(&'!"&%#""+$(("%'!"+&)$*'%"!)$""(*#$(((&*($&+#*!(*)#+"%(##$#*))#+))$"%#))#"#(#('$'*"+')(!#%%&*$"&"'%(+!*)*))&*'"#(+''#%'!"#(*"(+)#%#(&(%%"*((%&!'+)$('$"%$%)""$+(%)#))'&**(+'$%""%#%*+''"+("&#+%##!*(*#!'#!+!#)###$"#"'$%##%$!#$%)($#$()#!%'#"*(%*+!)$$'&)'%%()$""""+('&!#''))(#'!*'%&'**'+")!%#$!+&%)'$#+&&!#%*)&$!#)'()"+()#((""+&'&(#'!'+'%"$))"%+"*'*$*'%+""('*))*(+$#&+"!!)%%+&"'!"+'+%&""%*!"!((+)#)#$)%*!%!**&&%
@r2988
TCTTTCAGGCGGCGGGTCTGGTCATCNAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGNCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATNGCCGTCAGCCCCGACGTCGGGTNTGTGGTCAGCCCGAAGGCTTCAGCGACCTTGTNCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCANACTCTGGCTGATGGAC
+
1DG+G0(5"H(!DEF(+;D#5"19&8G7%<%%#@=-G<)&#19H@!8?E&,,?H+C.17<8'@B'A&8#41$3!BE##E><A++:!;C57/,260B4$H2&**4,(:5228-?;HG?1.0=G&A*EC6&/6#!)"D:(=3<D,0;75D:0372(4B)2$HA'<:0<?8-:">+:F;:*<42B?6EB%+$'",9-H:9$D$1)!;0:<!#31";+3A@9+HA682H/FC0-2F;?12:G!2DE.4#&3D<<#BD"F
@r2989
ACGTAATCGANACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAACTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACNTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACNGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCNCTGCCAGCGCCGTCAGTGTCGCATTCTTCCGTTGTTTACCCGCAAGCGCNTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGACCAGTTCATTCAGCGTATTCAG
+
!&((#(*'&'"%+#"()$!*#)*+**$%*$"!(%%*$))#*")+)"%!%'$%%##!$''((%&))"$!%)$"$)&'$*'&&*$$*""%'#"%$#'%"$)(#++%(%%&'&&''*)%(%)&$'"*%!&)%#'*'&$")"$'$'""&%(*!+&+#+()$*'$!))*("'#(%$#&*"%)*$*!%&($*+&"+$%*#!##+(((&"#'!'"($$##$%()*$#)('($+'$%$+(&#($#)#"%*%"#$+#$(!!"%*#")%")('('#($)!('#%&!+**%'&)!*&#'$#!(')')*"&+!(!%&#*$!((!!$'+(')%%'+'"))!!*!(*"$&&*!!&**!)$(("(+)$(*"'(!*+!+*#%$$!*"(++!#$")(*")''("'$&(%'(')(!%"(&'+%*+"&#"!#)"&%#"+!###*#%'(%)(!*)#)"+")%%''$+&!!%#$+)''!(%%$"%))+"#(#&!*'!)))!)'!!**#&(%)()*%+!&*+!%)*"!)!'!+$'#')#&$+!)%"("!!&%%($"%%*&!##($%%)%+'!+!&*&#&+$$%$&*+&(*()$%%"'%*(
@r2990
TCAGTGCCGGACGGCTTTGGCGGCACGGANCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGAATCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGNGATGATGACTATGCCGGTATCNGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGC
+
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
@r2991
TCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCNTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTNACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGNCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACANTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCNACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGNTTCCA
+
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
@r2992
TGATGAANTTGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGGTGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGTNGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGTTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGANGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCNATGGCAGCAGATCGCAGCACGGTAACAGCGGCAACCGGCATGA
+
#&&((('##')+)'+!''$'+(%$(%)&($%($$!&$'$"*(%+#$&$(+!!"*"+("*""$&$$$(*)&(**)$()##)%$$"&#&($%*(&!"%$&%%)!(#")''#'*'(#&#)+#'+"&!!(!('**%+**#($&"'$)"!+*&%*&"$!%#())()*('!')*$%'('!&''#$'%*!''+'!$%$$#&!"*%*"%$'"#)*$"&#$%##$#'+%%'#!"(+#+*$*!!)"'**%'(%#%&+")"*+*(+$*%$!#+!($*&)#&%(#%$*&(+)++"%+)'%&"$$"%)*%*!)!)*'+$%*"#%
@r2993
NGTGCNCCTACNNCGCTGCCACGAACACGTCAGAGGCCGCCACTTCAGCAGGAGATTCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATC
+
')&!!!)$%!%!")$(%&()')&)$$"")+$"("$)'!&*'%&"!'%%+"(%(#"*"$#!&)"!%%%'('#'&"&$&&'&)$(%+)+($!)&+#(%#"%("$+
@r2994
NACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGACGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTNGGTTGGGNTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAG
+
(1?+4)(6+@-&.*':&-$1CF3*?CBA/4@*"6*.D!F;G1F1#1"H94D()=21A?)G,4=(%</<69BB13H*<&90'B):9?2,;+#3#<AH8-C:)/C?-FB1:-!'>,5F:01)9(5@,<;@)6%052H1B=CD=/C50,/">A3.HE$=1/+;';*-:/'D7,F;)*-C$E$)GA67-!?0$G3
@r2995
GTTGNNGGGCTTGTTNAATNCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATC
+
!"%(("+&*)*%!!$"'+(%"$#"!#++#(&+#""%#($#&")%)"''"&')+%'%
@r2996
TNCTGATTTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCATAACGACAAACAATAAGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTAATGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGC
+
(%#"'&)&+&))*')%%'#!(&'*+#$)+()%((+**!+*'(%&%&!&(!'#)!+$!&#*)$&'!$!(#!())(!!'(%!"&*)!)&$$#"#%(#!%")'!%'#)'+&"(#+!'$#!+)#(""+!*&'&&%(")%((#'$(&$#$#+$&((')&""*'"))&')%)$+%""$#!'"!"'*'%'++#"#+%%*(!)$+)#"#$*##((#&())&*'!*##"'(&$)##+*"($
@r2997
CCTCATCCACACGCAGNAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTG
+
G+52;:=$'14!4'*<=C&&/+?!<?*+<&->:>,78&&7B?:C;$'=0-4E9EF"+A.)8@,6%(.,5**/'6'7)?>55G2BH%&8@C/A;%<7D77:"F$:<.:,10(=C$H)6C$.*>:.?$!<,/-'+8B(BHB>2=C"#%5HDHD!-%H4>C;-E<@!<$-:@.D@5#3;6A63.3&)8H8;(9H%52>0DB*=63:8$(0AH2'9A06$G7(%#H,,@?/A53D;.)2<*'*?GC<>*11!D@,.),6>2<,&>8"'+"#E%-/$+BG3#G>/<10(1+,2+.<#%!F)(5%E+@63,H?'E<.#F"*0=A";;DD+&*H,C?:;14@3#'"H7B),E.(A
@r2998
GCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATG
+
>D1A?<C85+A'B19!H9,<"*E4!G/&3:&97/G()E+%%.!G#F$=&7=.H&"'G7'D:<@;*,GEC()7.=.%D466(&@=1+##?#)HD2,/#ED;'4/C&!?38E?5.@A7./*F4)&=2'"=(C.,BAC#D+&+3+"#A6<(.603%&!=("'<E0&9</G5/0*$)@+%4=="6:7#,5.6F.<9962.(-!4@"D<+:'#7=H?!B4(>4/<F;/A5"&"?*-)3!24A6CD%!!7E?H3.3H"4*A5"&"5@+312%1FE&E5<*5+A%/531G?B-50?-4G3H8.A5.7.*'F?1!-B575,'E$B5#D1C>;2AF%G7BF-=5<&#+7%!1/*&-(+,$6#*A2H(2:8)!%*.--+D/(AB893(4A;4;!1.!8)4=%5=D)(2;C;"&(9=:*1A8/EA,H9?!;A5@7*$+3+'58HG?&?/B>227705/E?;7>
@r2999
CGCATTGCATAATCTTTCAGGGTTATGCGTTGTTNCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGACCTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGG
+
H4AH28%HAACG0;/=$CH.6C%3<+-E9&3,?CF:*:%30!:D1;4D.%A#5C!D("%&=,,,8,)751H29696-=3<4?@3-C7/8;(&*HB%=HH>2%**-0)>7'..H=B'!379.3=0DD,2)=0?D;(*F/(""=7<)4"0C(67/9=20(9GH#"(1B@6>(C';.'-1F88C270@;643!CF7B7D1"2#+*C*9D/!CB?15G*6+#+#+<D$FC".E=4"5.+9+2;A";!GD7@%+$46!#(6&!D17*CF75)720-7$0D1?&/(D>!>
@r3000
AGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGNCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACGGTTTCATAT
+
(?C7F'!$-'!%6.F%0,=":DB0H&70C.3A:D""%):5/!93(>>(.7E?G)C8G;4B3=(+9(<<26$1(;*CF@'219FF%$:9#H?3D34DD'F;?#+8:3.$#A77&;=F%#%$AG-0"'1A7<F2)>!'5D>(FD;4+*8=6+913"<;1=+
@r3001
AAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCGCCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATAGTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTNACTTCGTTCTGGTCACNGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCT
+
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
@r3002
TGANAAANNGGNGNTANCGCCNGANNNANAANNTANTNNNNNATNNNTTCNGNGCNNGGCGTNCCAGTNGNGGTNGNGNTNTNGGTTANCTNNANGNGCANNATCNNGANNCNGNCCGNNNTCTTNNNGGNACNNTNNGCGGNTNNNNTAGTNGTNAGCTTNCNNNTNGNNNNGGGANGNNAGNNNTGNGGATANCGCCNNNGANTNNTNGTNGNGNCNNNCNNNNNCNNNNCNNNNTN
+
!"!$!#$"$$#""$!"#"$#$#"$$!$$"$"!$##!!!#"!#$$"!#$"#"#""#!"!!##!#$#""#!"""$$"!$!$#!#""##$$##"!!"#!$"""##$"$"!""""!!#!"##$#!$$""#!"!"!$$!"##$"!"$"!#"!!$$$#"!!"###$"#$#!#"#$!"!!!"#$""!####!!#"#$$##$""#"#"!"$$"$""#$""""##"""!$#$"!!!$#""!$!!$#"#
@r3003
TTTTCCATGTCGTCTGCNAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAANGCTGGGCTGATTAGGAAAACAGG
+
/)"7"2C6<6;!:.AH.F*B,A;C%,B:">894<=;0&(%9"?>*F%A03/D"$%E4(-2""@/;30.?7.@<$)6;F1@49@3E.-G1"DGB-@'?A9B%5AF&82(-86.'1-5.228"G&7-8:CB3/DB(-E72EAG"'4C15'<-;E-ADEB.-;@;:/;>4&@E9:+5<2
@r3004
TATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTNCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTNTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGNCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGANAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTNGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCTCCAGCTTC
+
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
@r3005
AGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCANCACATCAGCAAAACGCNATTCACGCAGTACAGCAAATCCCAGAGCCAACCAAACCCATCGTAGTAACCATTCAGGAACGCAACCGCANCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGNATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGANTGGCTCTGGAGTGGAAAGCGNGATGGGNAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATAATNGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCACGGATACANGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCG
+
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
@r3006
NTGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGT
+
#B6%:-F(!<-E>H6)<;<&@BB7-)?*H=@.1ECB>!06B:!>5B(>+!!,+3*+265>4>G"7):>-$$$<E/6.)+476D01@+E9!@8C*3B)%&$!1?B;*69&!6$&H2%4H'H;./=:@&-D1?(+"2'19C<7H51=/!"H,/'?23-,8236+E3!$*9?#+%!5.>E;020/,4>/%C?B=$)+*>/F2'>.F"=H1?%&F4G=G'<)*@9G**-6#FH?<+HA8,E9'*$46%A*F58E&4F-B1ABD>:,;+:4=.E<4+#<C-#:E30??
@r3007
GCGGCTGGCTGGTGAACTTCCGATAGTGCNGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGNATT
+
*<0@FG=C/12(C'<<A2?E:;'1D)>?/+*8%<?=E910E9C0G9H0&24EGA*;&@5(:+,?7'/0,-8@+/'),$G/69#H4))
@r3008
TCTGCGGCCTTACGGCGTAACTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGNATAAGACTCCGCATCCGGANACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTNGGCAGTCCGGCGGTAACGGATGCT
+
FD5B0'5(*.@G98B24B#"@D?:@2G5*B4G%#9H(A9G:@7;B)159A>/8B(*AC.*,4#8@5H(<:#E9:<'8!E+23E)':5-/)@</%4CCC6/0+AE42EA#>7E,<07G/,A(<$8F4.F$5<*8@(1/>>.>,"8"17'5"G!#>"C8+H%7#GC&+%7#'7C"@+A,*D(%A71"1$/$@6F@A*$(/D,@
@r3009
GNACTCNCACNTATCANCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGNATGATTAATACATCATTTAATACAGAGCCGTNTTTAGTGAGTCGGTATTCAGAGTC
+
*"&&*%"()&$$&#))!+(*&%(%''$''&('(*&)$!+!+"('))##*#("#$"+($"%!*%")'%++#&!)'+%&(%#%*!#*!%$&'%+)$(#'!*&!#(#)++*$"%'$*+)!#$)*%"+)&
@r3010
TATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGTGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCNTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCG
+
0:1;6?;+6?F>)9@$GHD53#'00+#;-5C":48AF?<AH%G$!B:;=3D#2(4B2;<$=!6'9:6*GA-+."4'@3C5+'92@A#*)*7&?:F'H$BB6)%A=F34/)9,B(E7A2)H;#!0<F>&#++G5%C)85
@r3011
ACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCNGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACNAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGTCNTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGNNGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTCCTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGANGCTATACAGGCCAACATTGAGNTATTTTCAGGAC
+
<-+3B#B:.&D49@>8??::;H+0!#&$7#?;E**7D*"=$64?;A+D&#/!$;91$8#)?0"5=.:A5&<.,=8-)"/;**9D$?<%4%F$E:)D'20H:BD865/%+;(;G5D,/B%5B):,#?')6@<6(1.0=/?)/7%,F.4G3?'.53>%;&4D(5?<'3;EG"::?;)%B!E.4>B#A?,A.G)5@;1=9A,/F&G.$%G@*7,AE:01<(<&!3.8=>'DD2@58&<$E$$?EC?%@:"G*0<+4-328G0C4)D1B,F;93>68'!G$."+4'4D0D%C#EB/1+HH+"*',&8?'"5H4."H#>!G38+BFE-='G,H//9$F++;.-#@*A<;)-&4/*6E(?8.!0)6>4<G5$!9?=G-5";14(*C<-6?5/;-G?A%-=+=870B:6;-??C$$&?1:-B3C4$@,$/*!0'.8B));@?
@r3012
AGGNANAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCANAGGCGCGCAGTGACACTGCGCTGGATNGTCTNATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCNTTAACGATTNGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACC
+
)!')!"$(+!)#*%$*"%$($(('+""*"$(+'+%"")(**")+!'$&#$"&!%%('!!#"+%%!#'))*!*%%#%))&#%#+'')%!$"**$!%%$&%))$*"%"+$+$%+()""$%(+'#+('(&%#%!$"'%$&+"'"#*"%+'#%)!'')((&")(!&)&(&!$'&"'+&((+"++()!$$*))#*'%)&'"&%")))&!(&#%""##(*%*+&*(+#*(''!"('!')("'%(")&%)#)#*')&*+#'!)($')#+!+%%)!(&$+("$+$!&**"&*&*""*$$'(!"&%&$)!%$$'$$+!$*"!%!(*''&()"*$+')"&%##"*)+%+%*#$'#)#*+#(+!(*!#(#
@r3013
TGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGT
+
8EA8.B!+,30=!+H5#33HD7B$8G$26?;=904D7*<"(9%0/-#5:=(>.#&B&70F%5(D582@%%*06B%HAD6$E/?/"4F:1G/*A+H@D!6!9>.#D;,!H#G:(9<G#"/<?+*+B,4$/3*$3$-=,B'?1>:'3:?BE%9:(?/G<1@H<6?>1(0?;6'"%(B>6,:H&0D<E9"
@r3014
GCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTNCCGGCTGTCTGGTATGTATGAGTATGTGGTGAATAATGCCCNTGAACAGACAGAGGACGCCGGGCCCGCA
+
(&'$#)+(()'(%!"$*#+$&'&(+!!!)"*(*#*(+%$))&%**%*"#%'!$')((*$%(!()!!$$#&&#$&&*%'''#*((!$"!!)#%(#'"%)*")&*!(#%))!*"*$+#*('##(!**)!$&&*&$"#!+)!%"")(&#"(%%&*)%*$)$')'!&%'!!'$%*&(!"!)(")+*)!$&($**
@r3015
GTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCNTCCCAACAGCATTGCAGATGCTGTCGGAATATCAATGAA
+
.:266:60,G0A3<D!G%3+32<4'$'H4=%EC@H9#7F>&;(;<1>1B95'#DC"):&1&%.:==#)B-C47B>("C"575!2H.1:B2%ABE.4!"E=>*@+
@r3016
GCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCT
+
(7+#2BE!,9&;.39360$*7@$/",$;,(5CE6=D"$,B8/$+A(2E2'()%;1$/083#-?0=B.67/@?!"G/!6GA8G-5>EG.2>2C"9='5)#2:DC-2:)32?$;!/8A:G<F<,F3)+$H,8G=:,+8D$4G;:B,;:,:D=9+5(4E7<(5<
@r3017
ACNAANACTCNCNTGTAACAANTANNTANAATCGGTAGCAACTGGAAATCATTCAACACCCGNACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATANTGAATGATAATNATAATATTAAAAATTTCCTGTGTAACTANTTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAGCAACTTGTATTACATNGACAGTTAAGCNGTTAATTTTATCACCT
+
(""&"!###(!"&(&$$$"*&"'%$!()*&+!##%$++"$(&)*)!'+)%"#($#"#+#+!!(!$$#%+)&*$!$$!)*%+!+#*+%$"""$+)*(($$!#*%)%%*")'!(&$*$('"*#%'+%&!+(%#"+*#"+%%$!$#!&)($*(%+)#'!'#&(+*!)'$))#)&'+'+#(++!$)('(%*#*&$*$)("#%*'*&#&"+$$$)#")))+&(#%&+#($"!(*#!)(&)!('+!&!$&(!$%')&'+%++((&!+((**%'*$$')(%')!**!"%())'')#''*#'+*!***')#)#*'($!)'#)
@r3018
AAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCNACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCNTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCNAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGGCTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCGTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATT
+
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
@r3019
NGTACAGGNCGTNCGGTTGATATTGCCAAAACAGAGCTGTGGNGGAGAGTTGTCGAGAAAGAGTGCGGAAGANGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTNGTGGNGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTNGAATGCGGTCACACGTTAGCANCANGATTGCCACGGATGGCAACANATTAACGGCATGATATTGACTTATTG
+
:<#8<>B7B)%46,)<0'6!?=&-:>A;3@8+FA>-6/&+7*=(-*0FG:<+DA@1:AHD"=+&,D1#3EB)13A=C5A@.'E=%"60#/@AH,+8/A)750.@))#*>C#7C+=6&&+*/C@?<=+,B'42:>=+F=$4BCD/@'@-B-6)%8;F+841-$F1>;9%*!5G>5>+-9?3./60:(D>"D.,-H5;E#<#;&F2(F./%!>B%)0/2>B;4@2&;5"&5&64%183@-8//"A3=D>1E&445?$,F84A6!-55C##@*5EH0:@)F7<#&C<H-'!*+,B>'A/E#<1F&71?C!?<E2
@r3020
ACGGACCATAAAAATTTATACTCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGNCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCTGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCAGGAGGCGGAAGAAACAAA
+
=*3(F22)">?7"8>-G5;A>)HD1,+:+17%5"?95*3;G0:=H116<7*+7GFDH9=C>(B=:0E8BH2,/2.,"B#'F/'607G/:7+,CB5'6G(7G6;0D'4/8:*(9*(GC+1/$+A+<:<57--1422F7C4&E68C/>=1+=$$5-6-:70''B5%F0"6#-?!2<G%>>,"*2!&E$D/'.C=H!DA4,')=H"'%81?BE?3H)BC$;@:(0!A.7&(2CG2+!)DE"?.1<AH;41*'&B=9G2CCD04CE3#4:1/69E93+"%%.;@?,BH7HD;/(,H'-D-@8;'.%<:(&3.8=>":B$39-#AE*4??1$?/H4*"47;4F;!*%;#""+FH3C1!8#-=/G46#29&DG4G-
@r3021
ACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGANGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGCCAATACNAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAGATAACAGAATAAACACTGCCCTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGCCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACAT
+
C4A+(E$F7DA@$F6.H+-*,$0/>3@==><11:8F4.-"!22@8C$G,?>*&-;$GF47D&?'*H.@,H8-F$,@-@@&;**:3>4!?%C&(/*""15C+;&+=#.:86A0)$%%<(6,5;5AC.!);E!#A?!4*2=@$3,>$=?6E&:#2!<GCC/&8&(B<FHBG8;#B,#(C-1HC'705H5=#!B"<E)7*@A3*%=;0B-18.?)'F)96;:5(<)CH.)7G!#/G#,0C@9H?(38>CC+#05#;**BD@%;8B0C.6.1-*=:)>92+(H);G!$#5+="2%<8<18%>;!#/B,H$(;-<@7@>G%?E96BBB.+-A3F+%D&FAGAG*!HE8E"*C0$>$!>"*C!()%$!51<=05F9.37(EH*/.B59"
@r3022
CTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGATGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGT
+
%?$=B$)A3(A4(9:E(+5/D@ABHFB4CC8),<3;1%DD($*%3.<49'5=*<E8G.:)8,F<513-(5G(D8?(0=$%*0H?@2=(+%B;5-9,7"G+-EA:*B##B!5<509H1<.>640(&!2?'8#7G@""*G$9(9,0D)1,*.:$$<252:1?B-8;;H2E+*!1:4F'6F8F2!#E05.@(1&5;F"4D%DC0@8
@r3023
TATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACNGACTAAATAGTTT
+
13;H2DFC7/,19B0-$3@G@-:62C?5)/F,78*"#<7&+-BHE;E.6H<8!**>26$C9,3!>(??')>:0-H?1@>65E<+:/C7F>B1;:F*&9&C*6'F<47-'1!--@A.3:%E8,E<8A&!#E7-"G:#>6;@'"'.;:D#G)C&-H07:8#&@=2*HA-F9:BF
@r3024
TGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGACTAACGATATCCGCCTGATGCNTGAACATGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGC
+
#0#(DE,9"<+<$0F?=/@.>+5/4,=(&'1$@'55'F?&./?G!3A=:B$"6-@H#;A;+.+&,BF0.2;E<7&4H55:1!8HD2'':412-0H%-F0F$EHF,%.!E4#?)22B
@r3025
GCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGT
+
G:5*:E".B<7F2&#,FA5@;4F4/+2A*:AE2<2F'+339?/8=9B1A"F1291B'+>95B@$80?419D<F,&%68G9$&!-)5"38F)1&0H1%6A01-.01GF3(!391E?B-=C*48C4="4C6=1A6,<#*A69
@r3026
AGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATNCAGTGCGTAAGGTGACGCGNC
+
D261H>!$97B>(-B:,.F/8A5%8%?E@4!H!55D"/AC1;*<=$F/G(7B='G>!17,@H%A/B%3'?68
@r3027
CGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGGGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGT
+
D56)"'$-9*HG":949:/0.)ACD4AAA41AB'@<;9C$9,45GA#&G:>A#F=0#G>?/:5-@6.=%!5##?G&D%,EH:#>A,?4<(@@>5,>9&E/6%/8,/
@r3028
CCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGNATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGNCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTTGGGGATCACCCGGAACAGCCCATGTTTTTTCCAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAT
+
560!'E'H1H4<*)6'4@D=5$26GD)*;#7,!,14?)CH8C8@GF75@5/@B2"(G0:@5@+:-7%%,*>%C6%9=10A/!:41;=..31D1%%B6E*(</B@+&$=EG!<#E78>7E$:4(2;E!8*2(09&DE)'7;9//+7)5D?;37'+#,B;)A$:H#*>*+)35AE;>3:>(4"1>>.F87&4@*BD,)'2,676AF3$2,5,@A/$/*E/E/%?E,/$<%7
@r3029
CTACAGCTTCAGCGCCCTGAAGGACNGCCATAATGCNGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAG
+
?++F"!<>+H18AE5,63&%-#+$;13@G#$A&::61+:#9.5%!1.!B*,9F,'A,D,!*,F-*,='2E3!+;'&!58!F*?1-+22G3?<@HA"20(&4)>!3F':D15,.+A+*50E!4G2(5=%4AB#2:$65C@
@r3030
GGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTTGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACGCCCGGCNGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTNGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATAT
+
+DC):=2BD)C?>2B?E>4/A;@+'%E;F?5FH,(H:BD27#*21#-G'=81@13$D2:"950.!C/2)",*BGFA<@(!:(#59<#DD%/G')+E!-;A@B(?*-"(A2G-(;&DE09G')",:G$1EE47"/GE5+C*4;%.-8$E5-:+!0?&?6.75;.;:$10<=//60+&<087'2!139G'8<#75/),-(4,;(A"3,DE1@)B61/2+36>55'>=-@EBBE3"3<'3#6C@G21@!(/;+CG#)FA@"C!0,5&82C6:A9G9F>9/;1::;D7FCA*F3B!<D8.H4B2029&E@
@r3031
GGTTTTAACTCGTGAGGTGTTTATANTTGAAGTGACAAATTCTGGATACCAC
+
!+#'"!$$)#)%%!)!)*%*!)"$"'""#&!+%%)'#)#)%&*"#*&%$''+
@r3032
ATAAAATNAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACNAAACGAAGCATTGGCCGTAAGTGNGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCACATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACNAGTTAACCGCCCTNTTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAAGATGCAGTGGACGCCNGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGNTTTGTTCAACNCACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGANGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACNAANCCATNGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTNATCG
+
)!'(#(&!++&'))+(*&**&$('(+!(#'")&*$%%+%!"&('!&+'!&"!()")+(%*(+((!&+)$+%+&(#%'$$)$(!+*%"#%"%&$!)")%"#*!$$#%'!!$!*&*&#&($"&+"%+"!%'""")%)+$&#$&+%&*'"+)%#("(%"+"+%#"(%+)$&!&'$#("&+%#&!"(+*)%+')#+%!%&$'++("$'((&!'!!')%#*"%**&)"*#+'!)%&$)(#+$#$&*"+$&*"$'&()"&#)')**%)!%(*)#!&+%('('!!+%#+&#*"#$!#((+%+!'#(##+*(#"'**!#%%$!%+'##")*%)+%(!")'*+()*)"))!%($"!#!)#$("%+')(&('''*&)))*"*%")'##&!!*(!''(%$%"(%+#%())!)%(#'$!!#"$)!%*&*"%%!%%"&(#*"(#!#&'+*!+!+#$##""%!)*+&$+(##%+(%+()&)(%*&")!)%*+"*%*()("%(&!+)!$'+#(%%#%)$%!($+!%)'#+#(%'+!'!&($*!'&(&*(&+)"$$%$%"!$$(+%'*%(&+*#($#('(#!&(*#'#'"!+!%!)(%(%**!(%#%'#")"+++%!*&'$++&!"&''&'(('!%*&"*$'++"*&!"*)"$"#%"!+#)!+*'!*)+("!%&()#"(+**$'))*)#"'$$$)#('!+'+(#!'(*%*$&&!))*(%#%*&""+)&$*+)!*+#"#!''$*'*$#(($$$'%(&&+*(!*+*&+)%+!((*)+&+*'%#"*#+#%$)%")*+"*&(&#&$&&(%+"*$(($'&"*!!"&()+&#$$"'#$%&#'"(&$+('"+$"#++#*'$''+)')""+#%%%""+!(!"##'!))$*$*("&&*%#$*((&+#'#""*%"$(**''#++&"%""$!)!$"'!#&$("*"
@r3033
GGATGGTGACGGGGGCATTTGACTGCGCTGAATCGNCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGNCGTCTGGTCACGCAGACCGCCCGGACGGGCTCCATCGGCGTCATGATNGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGNCAACCCCCACAGCCATCTGCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGTCTGCAGTGTACAGCGGTCAGGAGGCCATTGANGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCANTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCCCGGACGCGAAGATCAGGCACGCGTGCTGGCAGA
+
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
@r3034
GCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCCCACGCGCCAGTTTCAGGGCAAAACTCAGCNCACCGT
+
6#9A1#=?-0'2A$)AH#@E/-B%0%DA%5$?-%5;%'*)A>@3<G13B#299!/#AG66B%$E.>!3=2!%F'#C56!?#"D-GE-(7-.67#+1/016*%
@r3035
GCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATNANGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTTTGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGNGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACG
+
G:*B"9-%>83,6B3!2>&F95%*(+7&,D3%8(?B(E%2C@?@0%=D2,"10A?),=3))*C>9,<BB;37+$#+855$"<?+*"@0<B;D$>8"9+;G#=1?=@3-=4<189(=F2+!)<"@!5516@CGF5(*-H38A(H)H(3$4/80?!.6=#.(9(111*<$44%(>4?6"=E!.CED'57675ECCB0;9A$0><6A?66:7:G*-G<E@8/;*>/5.H''"C(&6)4$9:4,A89,93-+GB.3=!"A/:A$F*A-?6,C1<&C=,&=23G>:(-5A<)+5&:;C=EC69@?''$738)">+8G-?6/-&5C(65;+-B>5+>7+31D=;(2:'H0"+B40F((/;=7(;#!83&B0:9)0DE#?7#A;)CA>-G>@)4"'E0?"@"85G%0G)?&5F,A-:$-E<$A()GA$C5(
@r3036
TCTGCGGCTGCNGNACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGACCTGNCGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTNATTTCT
+
(D7(;<'7"/HG9@=#%<!)!,'(2?6#D+0!3'!B!A=.+?C30$329(H>/<2A;<);3""A0=FA6F'5C-,06AG$F15A=0@G$B3B%,'-CG('0@353G#->0.>,;<4D51(A&@-2*G&.>B+$2*A,/!07@B>7:BDB&1GD)3D?0)1-G2773*D15-C<67B@)0$),BA?.&385
@r3037
CGAATGCCAGGTCATCTNAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGC
+
2"-2E,%FH#&G:=D:<$2#2?%,DF3.5469A##:@&.,=EC6>"!'5+@=3).@H0D5?F&;)481$)$EB(<H%>#=DHEH04,?'(9
@r3038
CACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCANGTTTTCAGCATGAGANACTGCCTCCGTGGNCCAGGNGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTNTTCTGCGGATGGTT
+
343:&?C#9B!>)*(20*>2GH>B/!7.;)@F38+A222&'D#<D@,C;A6@0G;>2?200<;C3:/%!C'70C*0$>4!C".#9'!,5E5B"0/=>H23$)G)%+@!/8!9>E$$0A>*A4H3+9939(H/?+HC)<+<0)-H7DE%9*"5%HFE'&!*E;4@$%4>)'66GF%>*%@'E-C@$)$@:2:?=>+7#B&?>+$+66F/6>!5,H09(-=6?DAD/+C?1?;*A7H!!%"/-16)!A<:4/8>8')?D2:9-<:$4"A>,FA*H
@r3039
TCANNNATGNGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTANAGAGTTTGGATTAGGCAGAGACAGGCGANTCG
+
*(()$*#(%"+(&+%"!!*$+!!")*#+*+%+'#%&$+!!$(+#!&+*&%*""'!""'$&**$"+'&$'##&%(&#)'#'++$**+""&'(#*'*!!()&++&'(!#*$&#'$+*#"+#%#%#*$$(+#('$%&+'
@r3040
CGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGNTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAA
+
E#';3'-)/'1(C$'F%0HF;7!F#-D,1C*D')5G02+,?A0+'F4+B32:'.AF#07H@D.C'!>;BH@4<-,(1%.=8:"5$-%G<60C?B%B#)#24F+;!%D194F>5<B*=&648557&&<5C528:6;F:=
@r3041
GCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTGCTCGCTGACGTANTATNCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGT
+
-"<4,@)/3,&@/:>)1;<3C5)0E2%C)E6A!&$>5>$HF&(8"(E"A676G%/8*$&<B=?%(6;$H#HE.AA8A-@<FE<+%.5>"A=%<89BBH1,3*D7<.-00*0D--&.):44.D(7)F;'BDB4C!*%?F)+5E@>(G&)3,327+*4A''-0F."&>5H"%0;7C?."3-4>H+5"G9BFB'/.GH(=-#)#3*3D=B$&&?DB=G+B)4'>(.1;!/<%"!F<+6-">8;=C,>B1G>
@r3042
GATCCCCTTCCGGCGTCAGNGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCGCCGGCTTTCCGNAGACGGATGCCCCTTTTGGGGATCACCCGGAACANCCCATGTTTTTTCGAGCGTTCATACACNATGGTCGGGTCAATCCCGCCAGTATCCCACCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCGGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGNCAATCAGCCAGCTTTCCTCACCCGGCCCCCNTCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGG
+
%E20*5*E;5>?;:H49$64!D#A?,&;!8)G2/$9+;8(##8!(,2?(;B5:=!='H1G2<!/!,-B2A7F,(5*2?!-&"%*@.()";.F4B$)$1<@85'2;:4H.4;===2!'86A?=-;HG39H(HD6)68-),2BFD=3,3H@?5=@*,=5;1;)?C1A"@*3E="$118D)!*3F$5*5*:8.=H>(;9HD747)";G,!ED#26$*)C1*H+C+!=4)*/$=(C+-;:F0;E*1B-&@>?751.:C#@*%G4,=97%(#:2CC;B/%&FG315?7E+@(3*,@9C'C7,E?$1%33)<"7''"#9G8B"2:25@1D3G,<@<A:3+9%44A+)CA*4"@1:G#D!96%2;-=E%()'BG;E=E@8,7F%=7B0HG,+!*>?7#0$(@@!<,>:E13-1'19.1=&?)'>5
@r3043
CTCTTCAGCAGCCAGCTGCTGCGCTTCGGTCAGATCAAAAAT
+
6<9G8FBHB$1.B.@2H6<B&/6D&,%)#@"&*>DC%&+%<%
@r3044
ATCCATGAAAACGTAATGCACGTCTGTACCTGCCCGTCGCTTTTNCTCCATTAGCCAGAGCAACTATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTNTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGNCTGACCACTTAACGCCACGCTCTGTANCGAATGCCTGTATANGCTCTAATAACTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACNTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGNCGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCNGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCNAAATAAAAAGGCCTGCGATNACCGGCAGGCCTGTTATTAGCTCAGCAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGNTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTNGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGNACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATNGCCTCTT
+
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
@r3045
GCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGG
+
BDH@G5'-%")'.8;=!0%AB,$(A2F,,F;F2'&.>HB9"8+7E2G+!#5+=%3,C78=">.8*--4E&(396""229=2$+'<G.0;+A"!@2H@91(1%&AA/GA8(1=",957'$B:<<*%#1(0D>88#(1?,)5!F3-+=$GG!:$!CDA>64,=(52.A"3D+*B#@(?36!;-FF!CH9,C674(/'*F,BB*'*/?+@0:(8&14%3=D2)0C74B4=0==5%&G51(.)+<95<->$E9C6.78
@r3046
ANGCNGANTTCGCAATTTGGGTATTGTTTGTTCCCCTGAGCGCGGTNGGTGCTGTTG
+
%$&''(&''+(%)'*'(+"'#)'#"*")%%'))"(%#*"*&)+%!&&$%#($#&*(!
@r3047
AGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCNCCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAA
+
=63F0H3*0@:!$*G"1D''H$DH("+3&17><7)).H#G5+9.0-609(D$-,GA@D1!!9CE7@F&7$+=?/+G=:1H-.'G"D/18)E0$=(30AC:H=:+=A)/@A)::"@((<<9.5?.<".<>HE;F(D9B;)</G'37+H+%254,)?$.';(8B9B>-@,0;5-
@r3048
GCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATAGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCNATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCA
+
>/?09$"!-#$!<-B;A&8@"488$F9':D5/'E*""B4)'20*:%.?#0'+H"<G'!&4C5BEG;8>*@.3"=382<$"=8F$';F@B+2<#$1BH+&0"&*6B'(<##<%H.*5C80E!,*A=>&=-DBG=$,(';H,":%)E4F?-:+B/H89@58$5<6>&>(+?2;;=B<>@7C3HG@96
@r3049
GTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGCCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGC
+
"3+#5(=#)7?#';"&6)4;7D*,<E548"<48;%;)!FH8#:.AG4DE/'=F@0-0)-&,A?,F12$2-C#G9BBA@,AB*,55*->8$A;6HE37)(&%;$<8=%5%-"8H5:6D+>H)A(AE+%FAB6!3%98,&"&#+7B16E1(G(><&@<E-<3'+<&,A5*E':8)B+,-:6?;?A2-(C6!2&3+FA<:D7
@r3050
GGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACT
+
(409A?=#(3H0HAB?>239/5#"'&80G%,*A+=(.=0$A3*/AA:A#=#/&F9"#$/54C$6>D8,"H9"@(9F(,@;0%@85-9%A%FA01?%>+$/C%&?@)-=0E&%0FB7;#025@C'$'D.7<:2"8(+4?,%D!8F87684C.6-)(,%<3B=;A=D,7<3=%+HFC<0=.%#@.CGB2>4?*%%@'@D*!)(<":*28E799%=('9/(E=-8<H1$7DD).->E?C!6'0/%C,1A&G2@(11G$.!7E<H?4?5)6#<+&B=)B:%('=B)C((.H.<!+'%B8/30G:"!"73GG>!-;.F14.:?E*,$)"6$!F9)'2
@r3051
ATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTA
+
5"HA/9,"?%2@&3F;.6;5/=%($,)"7/-EG&"&5*=%%2/.6HH@#)<D8/-,5%@E;A)38&BBA'C?=.('4/)"D$!A"&=)#BH1D%'2
@r3052
NTCNGNNTNNTCANAGCGCGATATGCTGCGCTTGNTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGCCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCNCTACGGCAATAATCNGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGNGCTAACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCTGTACCGGAAAGAGAGTCAGAAGCCNTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTTCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGNTTTCTTTCACGATCCCGTTTTGTGAGTTGCTAATTCGT
+
$'!%)&"#$!%"($(+("'$$"("$+&"*$+*)"(*#&#(+'#')#*))#+!+)%()$("+*&#!'+&(#!$+)(#)+&&%&+"()!$$"""&!!")!()#('*&*$!#"*"$()*)&&(%+&(*&!$&)*++)%*)%"&$((*)!&&''**'!$"!'**+*"#+(+#+#"$&)%#)*!%!%*#'*"%*'!!$(++$!#)))!&'+#"")*#'"*('!%)$%"$)$%+('*)($(%("*#!&%+&'#$&*!(&("(&'*&&&""('%!+((+&()%#"(#(%)"$('&#+$%%+&'"##*((*$+*'$('&&%+&%'$*#!+&#$"#))''(*!('$!"*%#!'#&'#+(*#%)$#')'!*'&)*%$)+&++#"!%&"#*'%($!%)"'"!"(")&++"!%*&)(++&#(#+$&$!)%'(+(*$*%*+*#!%")$$!+%#+#')&"("(('+%(((&'#'+($((*'+&%!!"#+%!$$''+!($&"!('"+*+)()*%**#+"++'(&#&$#+*)))*&*((!#'#)!*!"!"&**((+"'*)&'*)$'"$)#$)!!)#("!))*!"&'&)"+$!"%&(")!')'&"+#!("&#%)!&#*%++"&+'%$*)()'(!+*)&')'(')##"""*!#!*$!%*!&'*'"#!$()&+&#$'"%(*&$"%)!(!!'(+)
@r3053
NGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCAGCATAACC
+
)5>$F54?6(,)E=9#+08%99+74<)@:.$!BB*+8$A,",*A
@r3054
ATGCAAANTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTNAAGCTA
+
,-1C<GC,(%$;,/7H;A!1,,.F=E5$<H91,@E>82&!-+(D$B05G,8%@=1#6C-D*'=8!AH/2+E7(2$!#F:*'7%>"8D#6$)8EG&8.@B(+>!993@
@r3055
NNCNNNNCCCNNNAGGCGCNNGNNCNNNNNNNNATNNACNNNCGGCNTNNNCNNGNAGGAAGNCNTCNNGANNTCNNNNNNCGCNGCNNNNGNNGNGNNANGCNACNNCNTTGGNNNCNNACNNNCCNAGNNANCNTACCNGNTNNTACCCGNNGNANNNTNNNCNNNATCANNTACNCNCANNNANNTAACNGANGNTANNNNNCGNNNNGTNANGNTAGGANNGAANNNTACCGCTTNNANNNNGANGTANNNNNGGTNNATGNNCANCTGGNTNCGNANTANANNCNNANTANNGTNANNNNNGGNGNTGCNCCTNNCTNNCAGGNNGTGGNCTAGCNNNTANANNATCCNNCGNGTANGNGAATNTANNTTGNNTNGANGTNGNGTNATCNNCNATTTTACTNGGTGNNGCNANNNNGNNNNTCNCNNNNNCTNGTNTGTNNNNNNNNACCGCGNNTGNNGCNNATCCNNNGGNCTNAGGGNANTNNNGGNTTTTNNCNANTNCGNANANTNNNCAGANGGATACNANNNNNNCNNCNNNTNNCNANNGANTGNNNNNNCNAGTNTTGCTNCNNGNTTCNNTNNTGNATNANTANCNNN
+
!"##!#"!$!"""#"!"!$!!!$!!##!!#!"$!!!$$#"!!#$!"!!"#####"!#"!"##""!#"##$!"!#"!!""#!$#$#"$!!$"$!!"!!!##""$$#$!!"!$"!""!$#!#$#"##$"!$#!"$!!$"!"!#$#"!"!"""#$#""##"#!!$##""!#!"!$#!!#$!"!$#$"!#!!"!!#"$!$"!"$"#""""#!#!###!$#"#$""$$#"!#""#"##!!!"$##!##!!!"""!##"$!##$$"!$$$#!"##!##$#""#$$"!!#!#$#!!""#!$"#""!"$$#!!$"#$$"$#"#$#$$$$!!#$$"$#"##$$"#$!$!"!$$!###$#!$$!""$!$""!#!$$##!#$!!""$!$$"##"#!!$!!!"!""!#$"#!#!#""#!"$#$#!!"#$$$"!$##$#!$!"#!"$!$!!$#"#!$"!$""#""!#$#$"!"#"$!"#!!#"#$!"!""#"$!!$#$"!##!"$#$"$##$$"$#""!##"#!##"#$##$"##!$#$"$!""!#$!"""!"#!!$$""$!"!$#"$$$"$!!#$"##!#!$$$$$#$$#$$#""$!$"$$!"##!"!$#$##""
@r3056
CGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCNGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGNCGTATGGCCATCGATGGTCTGAAAGNAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCGTATGCGCGGGTNTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGNCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGAGGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCNCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGNGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCA
+
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
@r3057
AGATTTTCAGGTATTCGTCAGCCGTAAGTCTTGNTCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTNTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCANCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGT
+
+C33)6$):4A:=)24F"*2+C285GHE69$3)&<4'&<:76AGGH&B!;E;-BE5A!'(4&6)GE'553E*H76GE9,*@*FA/H-%FB?5#41<AFB/)BG.&;+*&+*0BF'1663?HB-CF.,H;>.,/.6AH(*F"9.!'G3A98A%,)<GA+?3."*DB(30<@&HG0$B054*5<-/;852B0-;)C$*!%>%19+6@'55D+4+EE,A1=6>*1>03(7E##@"GE19%>-D5+=.B8<E.&D3+.?3E08&-F.@H90A;2.6+%<C3!&26G'E+:A@)#=C+=,5C:--1%9067.,B'3,*6='F&!#>A*%65-6)B+BH*<:02CAC.D+-&3:@.;B@*>G8*:6!?%!50C",%-E+8B;H<$BH/7"
@r3058
TAGCAAATGCTTACGATAACGTAAGGAATTACTACTATGTAAACACCNGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGG
+
B%&#D&78+AF)0G;D+04(15H;C.,)2$"D<4$'$#8;*$9490A5$73<=!$B31GG;F*9%%(=H0?).E#0+F7.G?-F63<B!)HD%.<@.)3,B$@4@*B#.6="D49<#+E6!A8=:B'8#9F<=!E#G<7$:00=/*'@;#06!,8@)=B>/=>20(1),2+F+:9:'>/5:#;/CB&$B5<9GC@#9#1.+8H31,F"B>C&*
@r3059
AAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTNGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAA
+
C/2CHFG)"EH687CD</3>F7"!>3#F<::7,F+%G9H0;?<#07:=>%+1G>1:.;2.G:A<CG@,4=</;*"/94&H4("@A3GG<C,GC+<1D+
@r3060
NATTAAGAACAGCCTCGCAGATGANGAATCATTGGNATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGNAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTACTCATATGCATTTCANCGNCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGANATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCNGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAANGTCACCAATGCTGAGATAGCTGAAGAGATTNCATATTGCTACGCAAGAATGAAAAGTGANATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTACGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTCACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGGCTTGGGGCNACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCNTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATATGCGGCTACATGNTACCCNCTATCGCNATCGGCATTGCCTCTGCATNGTT
+
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
@r3061
TCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGC
+
!*H*2-E!,"-)30,F0<$H*&%$8&=G.G12EB:*@1)0,?9-5-394;0'%>H6E,G&!5:6.5H52,DDH;HF)41@&-03.4/E(=-%H>$10)@E-GH<F-5C(((8G6073)H0='>F$!(?E$
@r3062
TGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATAAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGNTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACTGCTTCATACATCTCGTAGATTTCTCTGGCGATNGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTNATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCANAAATTGCTTTAAGGCGACGNGCGTCCTCAAGCTCCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATANGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGNTCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAG
+
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
@r3063
CGTCAGATTCTTTTGGGATTGGCTTCGGTTTATNTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGC
+
7HB4$A??><5D3E<376D1<(9/5//!2<HF/4%76:9=)G%H/A.3/4>*1-8/9/<G=33:<G4(1/*5-6A$8:(+9C;?((4+!6&H.-A@3A
@r3064
GTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCT
+
7C<";4(/B5:!./<99/'/9)$*F(:;D%2F100#6/;?3DGE)881F)9;8)0%"&$E.C2>C=E*6#A4/B1<4<H5(%44F?3E?27:)3;35"BD:H=
@r3065
NGNAGNGACTNTGCGNNGNATCGTCTGATGCAGGGGGCACCGGCACCGGTGGCTNCANGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGTCGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAANGACCCCGCTGNTGCTGGACANCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGANCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGGTATGAGGATGTGCTCTGGCGGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGNCGGAACGGCAATCAGCANCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAACAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTNTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACCGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCANCTCNGAATTTACGCCGGGATANGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCNNATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGG
+
!$!&"$'(&""&))'#$%!''+(%%('!'$$#'+")!)'("!"())""+!'$(&*&%#%!"'+!!$'#!)+#!&%%"($(!*$)+$*)*#%%+)"$')%+'*"$)(((**""'$"*$'""'!$)!+*('*%*$"%("'#%$!)%*+$*(+'$!"(%(($*$+&&+"#&&('($'(!%+"%(#')$'))**'$&#%#"%'()!+!!*!)(('+*"!#'*)##$"&%+()!*"*&&'*%)&'**%*'$*$+*(&%$)+#!)+)*$)'"+($)%&!+#)#()$#%%#"%$"!%&%(($&!$!!(%)+"#')#!)#*&&(&$%(("()("$!()++"*$%"!"'))!)##(%'$!'%$''$#)!+"%%*&*+&*&*&+&!('''!&*((#'*"'*#*("$*&!#'#)""#"#"!%!*((&((+"')")'!%+!"#%"#!!%%%+(*)*!"'&!$("!$'*#+#$%&+)!'#$'$(+!'#)+'+)!#%)%+#+)%")"!+!)%+($&%)!%+$"(!((+*'%!&#)!*%+%)$&&#+&%+''+#')'&#+$%+**&'%#)%(%"&#%'*)%!)&#&"+($'+*("'"'''(&))"'"'*'$")&(('!!$#(++#+(!(((*%$%*"%%++"((#+)*#&+&!%')($)'$#+'"*&$!#*!!+&*"*!#$(("'')+!((((#&''#++$'$#!'$$)"#+)#*))("!(*'!!$*((#!()+((&'#'#")"(+!$&*&!)*(++'$+%$"#+$+'#%"%)$%('++%#)($%#(+#*"++!"!*&)'%('&&'*)+'$$''!"+%%*&%!*(+!#!"(%(%'!$+&&!$)$&)!'+''(%#%+"%"*$+$!'*!(+*"#"#(+%*'+('!%%)%(#&()+*$*
@r3066
ACAGTGCNAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATG
+
99)HCB$?A48,:2A&7E$@F6B5F:2#B9(7%H??2;:G2#D*A8G046G?9434(3G*G9<*0HFF&@?#,)DEEG;F$-C&@7-,?E#:=%'B-C-5>HH8D3.+8D$30$7(6?3GA#:#D;=!#9-(:/62&G.)HE8%'>(",&E+,<!FDH7EAH;C"<">'5011$81?#<9#42<.'@5
@r3067
TTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCATAGTGATTTGCCGTGGTGG
+
&6@84#7,4$F4191+/1'/4H*H3"88DGC1*+E9$49C9=7,5H%'6D&C.$>H'(DCC$.@A+6':,$2*+1#B;?46.",94>F/&2'%:$%";61F"C-<7:?6#0A6@=*,-8E+6=2=*&(-9")",/'8FC
@r3068
TAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGAATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTGCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGNACGANGCCATTCTGCTTATCAG
+
+((*+!$&+&'#('"")"&%"#"*+($+""!!$)""%%&%$!(*!((%)+((#$"*#&%)'(*!&!"+'!&'")'!!!##'%")*%*)"''&%##!&&!*%"%#&"!'!''($"($%'"$"(&$#+*(*(#+(%!)&+%(&*)"(')#&&&*%&+#$)'*'%***$##''&#"+'*+%$*&%"))#&))*)&+%%*'+($!&+('$!()%)!'%+%$%(&'")%+!"&&"#*+##)!!)()'#$&")#%#*!"+##%&"+%#*(%""''#$+%$#)%*$*'#*'&(&+""%"('$""$!"*+%%"!(!!)%&('$*'%%*+)#)"!"!!#($+#!)
@r3069
AGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTNCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGNNTCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTT
+
9E@A#;2A*$363/C$F6)%B#)84.$82=C.@%,?;=,F3AD1(=#2(>0B;7/E.;8/.*74$@?'0-"G2,A':?*7.2H.F'.BCC@=A:E=>&E6"<#EA68-;G52'@C;@>F-C!,"%:5)).3+G>-@(;(F07&>'61;"HE(2B:',&3.<6E;499?B+0.=<(/-0;E#6F>!=3/7&>@?74/E6GFG%:(H*%+1
@r3070
GACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGANGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGACCGAATAGCTCGATGCA
+
>4';&H=31G((C"#0-1FD)0$,0,#F3,2"G5$7420A>%9:;#9G%,33';66>?&1FE:3/@F2C-E-!'DB9,?>:'B4(HB%;);-905F876G??<2F="C<D9@:<3(-BG):C10%8&7E0-B(9'=<>2=:#)9D8>%ACA@9<)33G,!&7/B,*7"'$2'*77FH7.1!86GD%3?5=%4CE,H)&(A@<A1%*DA46?90,'3#1>3'4@H%%/57,.1<&<D)2#&C;(&5>;H4F!7)A$52&->''>H5H(#5#&7GH/35A%@7(%%$BC/H44D(6823*=5:9,;#<$'2-3F=3
@r3071
GTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCCGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGANGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTCTGTGGTGATGTCTTCAAGTGGAGCA
+
9*-'-G)$.;@,91B"=?7,&.G.H-*3%;E&7G+H33;-7CC6"('F!/3;<?!5<CEH%#;06-)7DF),7:7<-991G@0D3B!2C6:!7<>F065142,DF)C?$/G$@*2216/;##5-)2/E*?7A&?D0'//&HDD<#3-FA@7F1E9=,$-"F09&:)5-GAE1".@;4GG,50*:'CAG3''CD&&C=G>?&"+3$0A5:H0%+%<'G
@r3072
GCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACACCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCNGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGNGCGCCTCGTTCATTCACGTTGTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATNCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGG
+
%+*$+'"&)5'1"):8#C@#H9;@(&52@A;>30#/D.DH*;+622CA!$-%.9F?.&%H2<BF.'>B>43:)*<+6%5G;H+(#%B,06?//=:79E'/?:2)2?7<<F3%(3&F+*-,174:%5:D<9D73,+/.!0;DF"9135+5>B/84%*:;;9C)/#54)7,($H5'C($6@'?):D*(CBH:A/3@$F#@G;F8*/#=CFC/!2F*;B;6)'"7"#F-H$E4!?>%AHA6A*2'&$#)>&1!<70?+C++'163?4"?F8+;"4>+A-!!560';83).4;:2%D.0&/<%"D09@D(5/?(6@0-,%E#)=3G1CE1+:-&:?1:G63$!F+)'?4+.8G9$C092G);2)5044..2D7A23>#7:>E*A*6E8E)C4">0D/$%;(#A%E!6DCH5FE$HG7;7@F/1*7F"=;@E5F;8A#'72$86D43(F&G;3D(=D;%A<&!A7#""(25,@FG204*%":!E%;:"B<A)=G-$BE#,E
@r3073
NNGGGNNACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAG
+
'#*%)"$+()!!$#&!!$"'%$#)'+$'+#')$&$'"(%(("*('++)('('+*$&
@r3074
GCAANNANAGTACTCATTCGTTTTATACCTCTGAATCAAT
+
)($*""$*"*'+)%$)$+*'$"*$+('!#)"($'!)"##"
@r3075
GAAAGGGGNTAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGNTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACAGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCNGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGNCTGNCTGAACTNACTCAGGCTGGCAGGGATATTCTGGCAAANAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCNGTTGCGCCGATCCC
+
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
@r3076
TGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGCCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGACACNGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGC
+
#)3/,H8F9!AD.@B/?.3$,#0"D3%98%@8"'9>(.7/7++C2-)"&D7!"GB+=#3HBH<,?7!B:5F9-:#G#F3E.*C4=B</3*;6*E8-:B<3-6/<#4FD9,"&%$62=C<6H5.:>;2?1G*!178E+@/71-3G.5"#?.5$4"<=FA()D7,+:"0CF&<$*5#BCG/$E)C,*9$#@+$@!A#B7-E:B74!+%--&='E&*G7*?4$A8#6&EF<4"<=E1"H@7(+,"@DF(5F4GE'8-+2!6)B?:-12:">,GE.$2F0*3HC-@A)8+)5F8>,<A>D7,394DF62=0&4?(%&
@r3077
NTATTCTGAGCCGTCTGCAGNTTCAGTGAGTCACCCGGCATCAGGTGCNGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCACTCCAGCCGGTCAGCCTTTCCCGCTGNTCCTGACTGTTNGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCTGCTCACTCTCAATG
+
!*$(&+"*!$(#$*(')&"&'*%(#'''"%&!"*")''&$$+'$)+)(&*&+)$&''$%"(+")'$(+)#(&)+"#$!*"&&)%*##+!#"#'#+*+&&$!$('(*(*&!$$+$((+()#%))##!*&+'##%#"%%+"*$&)'(*)(+&%++'*&%($+%++)#($)%*''+%('#+$(+)()'#)%)*!)!!+'%"
@r3078
CACAGCGCGATATGCNGCGCTTGCTGGCATCCTNGAATANCCGACGCCTTTGCATCTTCCGCACT
+
8(()1#)/>6?,.E!"3F90G/->/E8E94E*)65&2%$1=3;!9@?GG60%,=-B3!01'0.A)
@r3079
AGNGNNCCNCNATGNAGGNNTCGNTCANTNNANANNGTACNNNNGANNTCNNNNNCTCAAAGNTGANTGTCTNGTNNANGNNCGNNNGATAGNNNTGAGAAANACTTAACNAANCNTCANATTANTCNNGNCCNNNGNTNNTNNNANNCCANNATANTCTCNCANNTNGNANNCNNGNGTCTGCCGNTTNTTANNGNTNANACNCCCNNNCCTNNAGAGNNNNNNGGNTAAGTGNNTGGGANNNGGCNNNNGNTTNCNGCNGANNNCCNNNNNANANNNAATCTNNNNNNCNAGAANGANNCTNNTANACCATTTNNNNTTGACNNNTNTTTNTNAACNGTTGAATNAACTCTNCNCNGNNGNGNNNCNNNANNNGNGNAAGTTNTACAGCAGCANNTNNCTNNTGGNNANTNTTNTGNNNNGGCNCTNCTGGNTATCACNTTNGCTNCTGTNTNNATGAC
+
#!"#!!$"#!!"$$!#$#"#"!$!$#"###"$!$##$$$"#!#!""!!#!$$!""#$"""##"$!$!###$"#"#!!#!$###$#""$!##!#"!!"$"$!"#""#$"#!!#!!!!#!##"$!$"#$$"#!$$!"!$!""#!"$!#!"""$!!!#""#!"!!#!"$#!!#$"$$"!$##!!#!!$##$$""#"!#"$""#!#!!!##$#"#"$""$$"$!!#"!""""$!"$$"#""$$$#$$$$$!""$"$""$#!"!!!#$!"!$$""$"!"!#""##$#$#"##$$##!##"!$$"!$#$#!$#$#!"#$!"!!"$!"$"$!"$#"###$"$#"$#"!#"#$!!#!"#"!#!""!#"##!$!"$$$!"#!!#$"!!"$$"""$###"$$"##$"#!!#$"#""$!#"!$!"#$"!""!!#!$!$""#$$#!"$##"""$#"#"$!"!"!"#!$$"#!#
@r3080
CTTTATGAAAATAATCTCNGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGNTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATNAANTAGTGCTAACAGTTATCGTTTGGAGGCAGGGAAGCACTTGAGTGANGTGATTACTCAAAGACACTCTTTCGTAAAAGTTATAAGGAAATATAGT
+
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
@r3081
AGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAANGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCCGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTT
+
417B#!@3#%-,-2>56F<.69$0+G0*!?G%)>;C#E;D.>&(8D>D?4.*>G-!A$>F.F4%DF;C+(@;"+#DE*(@$--&-!+C14%,#E&'&2==+60+A3H*<+93F*-@85$(9.;513C!-1;;C1$%45&3%2-!A:.;H?52/'&=/HD7!0(@70H?82&H7=.GD1@?!C0/2>(!2;1)E/!:!B>-:/5,%80%,F!>91*;15"85=G<1!#<H26)'8FF50/?+"!(&3)-EE48:0B<9)9#BG12%>E:*12;!A134>+22E-A>&5,$?0FAB+D24*=EBF(9;439)><85"8<49D$.:.A&&*C/B3E"@"1">D<H!.@:F)AE,!+:':G%3!A-4>,E;185,9)/?B-A32#;"@%H017,,(9'@=C:A;)5C9D1$#E*%H48A!FC.AE,9@>F$A;%2/1*==<8/!<?1;07>)&D88:B>%1%<;8-E@%4!#,G"+?&37D."F8E*8<<;*+2G-)E
@r3082
NTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCNCGGCAAGGAGCTGCTGGTAAAAGTCGA
+
&-''=6C+.>@3#'D"D&@A#7&>)-DA52<::&*>@2@E:6#->DF6C$9""&*/B!'F(50D%G8./8D!-*1060F+(964&@82;E=:(4::FF4!(/43>$C;"/,G.-F?(#"1>7>/)>:7"A.@=;C9A@5FE&1+6!289C
@r3083
TATGNNCACTCTATATCTATACCTTCATCTACATAAACACCTNCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCGTTGATACTCATTTATAAACTCCTTGCAATGNATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTNGATGCGAATGCCAGCGTCAGACATCATATGCGGATACTCACCTGCATNCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCANTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCTATACGCTTACTCCCATCCGAGATNACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGNTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGGTCTCCTGGTCGCGGCGTTTGATGTNTTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATNGAAAAGGTCTGCGTCAAGTCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGNTCACTTCGANCCTCTCTGTTTNCTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGT
+
$((#!#"+)'*!&!$&&#("'$*"(#(!()*#!"&!)"#&%!)"!)%)%!'"'#&%)"**+!))#%##'%*'(&'+''"*')#&")(#($"!&!"!%%)##)!*!$)'('$#*!#&+')&'''&!#$)(&'))#))$#&'")$'&#"""&+!&"%%+'&&%&!'%)*)+'*$($)))#&"(%#&#$%'&+')""("'&+('(%+%&%!$)!!&*#$)#!+***"*+)*&*(&'*(+'(#)%'#'$'%(#+!"#%+)!%"'(($"(++#+#+&$"$"%'!)*!(&'#'*#&%&$$+()%&&"!&&!!(*#&''!%+")$!#!"#&'!$)")$$"!)&&!&#"!)()!++)%++$*"$'(!!#!%*$()!""'%!!"*(&#!&&#)+)&'&"#%*&!+)!)+%"%&)!$*%'"$!'"%*+''!++$&#*+&)#())!##!++(#'&((*&('#)&"(&#'+!&#++$*+&&#)*&$!!"!"!&!(*'+!(#(*&$#%%)("($(!%$+!+"+'+"'$'&')($#$''%*##!"!*+($##(&*&'#)*%)'+)#$!!+%!()*'!!'*()$#+#"(%"*(''%+&!&$&&'!#&#$$+%*)%%*(*$+**()%()#!*$%$#(&&'+"%%(!(!%&')('+"$!+'$#%$$&)!$%&*!*$&%!"$++(!"+$"#)"&+&$"$*"&$'"'#*+'&%%%&"%$"%!!&%"$(*#*#*+#('!*+*&"$&%&$)##(!#'$"*"$#''"(!(+"+!)"#(*$!%&+%(#$"'%&(!+&%&'!+$$)%!*#(!()*'(*&!(+#!"%%&))*$!(%!")&(!*&($$"$&+'%+&***))**$+&&+&%'(!%)**##%#&)"'*#'(*$%++)*)!+(")$!+*!!&*&*+)!'*&+!'$%%"+"&$"!"!+''(++*&#!+%$%'$#*(!!'
@r3084
NTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCNGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAA
+
%F375;<55H1.*7G*.=D<+A,,CE::B7)!G,@<2%D,!$G)9=C!3F,2()6316E&"4A"+7;;<)1?CFD!,C0@@00H3D?AA:!D=9.;*@>6);(><$%,-75&3182D%!98GA@'HE;D(&.0,-6265FE#&CG<5*,(0E-&4+0C5&=-HH-;GD1B;,<@//9:;-2G
@r3085
TCCGTACCTGATACCAGCNGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTNGCCAGTGCCCGAATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGNAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCNCGTTTGCTCAGTTGTTCAGGAATATGGNGNAGCAGCNCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACNGCAGCACATCGCCCGGCTGTGCC
+
73H)!C@%*)94:)5=!)H>;E'.%<.C,.0/7E7.8;.DG/6D/51G=B!"9*&!HA)9>!4<%>A@4(7G"@?7-)AH#2E0,%<,@+5#%=@(/75#=:/!H;%F%!>:0?BD>0?63.BD<(3,9DCE&,%(7+>*$1A$*F&><?C,4/26HE792-D8$0GD:"84)BHF--"3HB#A2=:3--ABE94A2?35#:)>#%416"8CC8D93!5&;3'@.)5*3F*:84)3#0/G$84E)/.F*+D),:D1)D/7+1D#07$*&/C(B3-65/3E"*499"&B66E+H*H+%7:88G9F166!#<,!H=-4F>$71&DC/
@r3086
GTCGAGCGTCAGCGTCCGGGTCTGGCTGTGCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTC
+
++&+'&**'"!##'&%(+"+)'&%$!%!()+*!#'&+#"('!%%'("%%!(#*+)!*&"+*$(+&&'+($#$
@r3087
TGAACGNCGTCATCCTGCGCATCCGGATATTAAACGNGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCNGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGNTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCNAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGANNATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCAC
+
*(!#"++*"')(*(&%!!#&+(#"#$&%'*'!$*)'+&+'+&$')+)*'*('&!+!$)!(#'$+"&*+&##!*'#!$&(%$"!+#'"$&+*#")$##)$%(!(!"%"'(")!#$+&'"))%+$%(*(+##*(!"!#"#!'!%+#*((+'&($(#&$&)$"*++++)&'!)!)$*!($+"))()(+*$+"#$""*'%++#%+"&"+!"!*(+*"!#"($'!+"$+'+#(("*('"#*!)"%'(#)#!*&%$**!*'##$)+)")&!#%*!++&+"$)+#%%*&#*&'%$!%*'%"*(++*((%"!!(!%"$#&"+%"#()&&+&"*+#'+")($*+*)'*)((&("!*%#)%(%#'$&!*)+)&)+'*&%$$%((&"!'#)"#&#)*'#%#"$$*#$%&(")$+")&)'&('#*$%$##%$('$(*)!%)(
@r3088
NCNGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGANTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGC
+
(!/*2>4)))B8,;@4$24<.":GEB5(D*&-@E*FG88C2:0HHE2-;.B+>;0A"A!12+**=)+EB&2)%*>:21E*$0G9"'!$/#@4'=98BF?-$<.++F&4++!6'?2B8,%7'!5A'7->4C:.#F400.'-,3H5>22>4F"<H))@(F45!&!<6>EF5?B'4@FD.+/88>-H.E62)!&708C8C%)
@r3089
TCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTA
+
+&)!+)*!!+$#'('")'%&&($(*'++&*!'+&%"+'"#*+*(*(#!#)")+%&&&$(%#+&))$&&&(%'*&
@r3090
NTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAG
+
"F2A,0D<$(EH<.7314#0?2G+(,9FA@F.?)%:CD44%77=
@r3091
NNCCNCTCCCNCAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAANCCACATCGTCGTTTGATTACGGGACGANAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACANGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGG
+
#%)"$+'$%%#+*+"&'!)&$%"%%!%++$)%+&'#*%$+)%$#&+)($&!$)$'#*"#*!(()%!#'*&$($&!*'$#'**$!&(!"%##"*#+"$)")!'!'*!"&%!#'(#$+&!"+#$%!($%'+%(+#!$(*"($"&($##("%$(%#*$'()()"+$)'((*($$$+%%!#()&*!*)'!)'*(&)(*%#)+*"#(+*+('!'
@r3092
GATGGAAAAACTTTTCTCTTTACCAAAACAAATGACNAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATANAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACG
+
38H"$"!DGD49.-&>=.B+"61.HD*:7=/.9.A4G>B6,!<ECC=HA,8%)%;HFC5#1<50%C6"H<A7?=B,9+73"*39%*$>-,-<'$(%:*&H,F*>FA,1>5G'/G12G$7D=)B3/H$,/$>H"C6/A8!:C/7;;F.0&(F+"9*<0%.,/+65)#A:)*>E:7:9'$@44*-':':5,+2*1,4*3<D%29CHD($"26<)"9@%;8%?'*G,0H'=#=?HG>8G37F+4>33$!#-!$%4A0//H@%(G;7=-?F'=.+/+3D=5#7G6('&G>'1(%;C:9%/G2G.>&'.&3<A.E:+9>>%DG4EE
@r3093
GAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAATTCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGNGTTTTCGAAAGAGTGGAAGGATGCCAGTGATA
+
>B5D@(+(H<H?@A$8E>52))'3-=2(G3>27;2(?5C*%A-CE->#=A-C)FFGBC=;"H7-($%9>4(8A639H)1/"8!6?3.9$9:9;E%%2=A643"F3H()0*9FC2?+D%.%8<%7#-<D,8!@>1,"*<,'<G*&1B-"9%>2!%>/$::5E=!$53(EA6=3&2$:9*9!7,+>'*;64@82!;;E$1+*,-/!B/)5+25#$+"3+<4/&%>2@/+9:">F5&1<$9F&1EGHC)0+G.$:/"F9?=$%:-7>2(49G42D+A-)G1$C>(1&08B"!284D5%$F7,*/+04(!!&'*<7?#E@=3$C#FC3)!3"B,%31*E+437%
@r3094
GAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTNGCATTTATCAAGTGTTTCGTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATNTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCNGAGCCAACATGGTGATGATT
+
((%+""("'$&)(#"$+$'!*"(+"#%)*%+*'#")&$"#+++%)#!('+")'"%#'*($$+!+$!)!**"&)&&((%*%#$*$&'#)$$$&"*()$%%+##$"##)"#(%(+(())"*"'#+$(%%%!&(&+!(!!&%*)++#%#&'""++#*(&$*(#%'+$+"#*&"+('+$!+*)!*')!!('*'#$(+'!!&%*("$+%$%$*%$&#%("*&"'+"+$"!!"!*'!(&&(*$)($'#(*%
@r3095
GCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCAATGGTTTTNTGCGCAGCCCTTAATGAAGGCAGGAA
+
:3$:;;8&52G1DH8&B1:C,979+6,F8C9".$&H!B5<8<3!%BH4F"=9=B/436(.FA1E?@!+9=:/
@r3096
TGAAGCGTTATTGGTATGCGGTGAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAT
+
-2<C6#282H2A*3'B$,+#.0.5@HA'46:3D:+%(F434F02,H*3B":1/'"--%F3<*=?5+#.)!H:0*@"F?G?;29GG@-/
@r3097
NGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGGGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATTTGAAGGATTATTCCCTGGTGGTTGACTGATCNCCATAACTGCTAATCNTTCAAACTATTTAGTCTGTAACAGAGCCAACACGCAGTCTGTCACTGNCAGGAAAGTGTTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGTTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGAC
+
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
@r3098
GAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGTGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGNCTGTTAACCTGCCTGTTCGATATATTGACTCAGCAACCCCGGTATNAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGA
+
).21>)#6+8#?@'2)H/0C#"?1-0&?''12$H)H!8"E4)51(<%5#3A*=G,45)+=!==854%G2G<F&>(=))A'8@3;1.-*3A%;B=;A0B"G%G'F%)*83F,!":5>B70.4?3&21:.8>**5@14D58G)!6'.%"&9C1,7,C%"0E1E;:+)<2'&;$:=#*6--6"48"#5"D@1=3.<C)=7F*53&79G1$4>+@=)&159'0*"00EAGC"@G&=-H9A:28+(-2'@)'.:+B?:DA'%1+'1DG->?1,C?BG6?<F)BFC!>FC6@&074+=H':??(2*"-=!.
@r3099
ATTCCCTGGTGGTTGACTGATCACCATAACTACTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCT
+
$0,=F4'"?C)$'F>::H>B02A/2*D6$56>6/6!;AFD&%3CA')1+@"',<2<310-(?G8FC,A5EA!-#$'&:B0$&+?-6C!,!@!E)%<B$='F<&?%DE9H=<+@-!;1?.$,'C0B45CD
@r3100
NCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTNCCTGCCCGATGCGGCTAATCAGTTCNACNCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTNAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTNCGCACGAGATACANGGTAAGTCGGTCTCTTTCTCTGATGAACGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGNCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCANCGAGCTATTCGGTCGCTCATCAGNTCTNCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACNGGATATCCCACAGGTGANCCGTGTAGTTGAAGGTNTTTACGTCAGATTCTTTTGGGANTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTGGCAGTTTTCGCAGATTATGTCGGTGATACTTCGNCTCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCANACCGGAGACACAATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCNTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATGAAGCTGCCCTCCATATATTTCGCATGACTCAGAACAAGAGCCGGTATCGCATCTNTTAGTTCGTACCATGTCCTGATACAGGGCTTGATAANCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCNTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTACAGGCTTTGGCTTTAGCCACTTCGGTTCNTCNGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTANTCTGTCAGTGCAGAACGC
+
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
@r3101
NGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGANGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGNCGGCACTGGCAAGCAA
+
"?#0G!://!,.*"E!'CH++;%/!38D"A2?#('!G62@4&:&DA?963F50-2)"-9!',4:CE;0A,E*G0E0CG:78>.%90A-.>G)185>1'H(3?;D#G7*-=(EE:H)!?.@#A@(C0/>G4!#*,!)!$9A::.8#$7H?-'E65G?8D".(''C;G#@?:=6$
@r3102
AAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCNGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTNCCTGCTCTGNCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTGCTGGCAACATGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGGTGCGCATCAGTATTTCCCGCTGGGAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACNAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCANGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCNTGGAACCNACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCNCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGNGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGNCTGCTGCTGCATTGACGTTGAGCGAAAACGCACATTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAAC
+
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
@r3103
TGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCGGCAGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGAGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTAC
+
H;).6A;=700/9%B%H@662336"8-.);>#:26)"/-9A$;4D+3232-4/'$50;14<#@5A,<-!**5+;7!G#>9DAHCC>>#.>%9/3*>$B470--86:?H)3<2=6!&D-9/?*!81G9EH117H(;*#C<H5#3E"($4BG=&?,B.=B$-;1!C(#65$#B*80C/8'95%694D.#."9'E3'2&F0A)2D1C9<B$86=H!G23A"5<2CC2&<'A%/DH&+0;!!$08#808-*;3"%<%6)$8!E19!+>1-:E$EFG&B*4&H-<G"6F2.)D+8;::9+)'-:7C0"1-4A;-*%C<""$1-G73#E!7(;E02,A!672/C',#,&8(6+E180&@%)*.8/H$7HCH/&$A"GH*H$D.!'&03$C?C8($B!;59-BA*&8"&%=B&1A01B6'1@'='2625<<+%6/8;!.'.B@$*ED#E=",8F>412'(E0H,6EF1:>.+>D"%E>65:,<'*E;@5;#1%D?6/G%H',H+-/01E41><6A.7(9&)E"";G4.(&2A:3(B?FEE78>2%@+073,1/*F"*-0@AA%A+3?"730ED$90)"0")4D)D0<:&G$6?6<B'H,#?!E3+--3?(63=A27;FD95B-:-<'.A%,<"24B9(9!4.$%#5><B##4,.%&A))&H3<=4%
@r3104
NGGNGNTCTNCCNNNCGTCNNTNTTTNNTATGGCNGGANNNTTNNCNTCNGTNGTNCNNCNTACANGNTNNNGATCAAAGNTGNNNGCNNNGTTNANNNCNAANNGNNCTGCTTNNTANCNGTNNTNANAANCNGCNAATCCNAANNNTNNNNNGANANANANANNNNTNGNGNNTGGACNNNTNATCCTNNNGTGNANNCNNNNCGNATACCCNNTGNTTNGGCNNCGNTNGCGCCNNTTNACTCGTTNGGNNTTNTNTAGACCCNTNNCNTCTGNNACNNAGTNGANATNNCTTCNNNNTANGCTGTNAATNCGGNGNGNACNGGTTNNANAGNAGTGATNNCANNNNCNNNNNNCNNNNTGNTGATTNGCTTNNNNGAATAN
+
!$$!#"#$""$!#!$$#""$!#!#!#!"!"$$!"!$"#!!$$$!##$!"#$#!$$"#"#$"#"$$!"$$!!"$"$$!"#$"!$"!""!##""$#$!"!!##$""""!!"!#$!#""!"#!!#$!!$$!#"$!""##!$$##""#$"#$###!#$##!#"#"$"#!!!#$$$!#$"!!""#"!##$#"#!$##!$$"$!#$""$#$$#!$"!##$#"!"##!"#!#""#"#$#$"##!#"$"!#!#!$"##"$!#"##"!#!!$!"#!$"#!#$#"$!"$#!!#$#!"!$#$""###$#"!$"!!"$!$!""!$$$$##!""!"#$#$$$!!#!"##"#!"!$!"""""#!!"!!##"#!""#"#""#$$$$""!!!$"###!""!
@r3105
TCGTGCGCGCATAAAANACCTCTGTGCCGTATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGNGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTT
+
5%5*7".<1CB&E":'6<H0&-F(H6**H32A(H&%=H=+#5&8(8:H2B<#&H@)B"GH@;7+!;58(!%C9@EF.7$3F#5E,F5A)?9E>3#/2-&#:#A,6?'D".12.F>8=C#B)E:1'*#%9('",,0:>$/,<C,''$CB.7H<&'>4<9@!770)47D(450+
@r3106
GCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATNAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCNGTTC
+
=D&F.211%G"";D/;4?+EF15>D8!6*GB7*)C+<#+4E)80%#67,)4G5C(?F/$H#27FB?5ABG<F<#E7D$1>AHE$%??*7#=;H$E:(*6/'9,4#+CA1:$7$51#D'#G2H-8/9F.65,5E'*?">=$6-(H&>>*.&:+?)H%F33HED=1.;)/,2-!<<+C#
@r3107
CGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGGCCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCNTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTNCGGTCGTGGA
+
?5=)/#+5-(8:G"@2BF'$:&C81%!44!;D6=,46<$&?)&AD*/74%-9-(BC,1F#3#&B).15*H!.%1;$7$500&.G-61H-'H:1G*C2"F)"'3;!6<2F+32*CF?,)9!;'1&@+G@DE'==@4H@HA/=(9*#-F3GH/*'C0C0:A;?$ECH#%5=.6E-#%)+#H*=7B>"/.<D-61!G#,2%%!B>
@r3108
GTTGATAAGCAACCGGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCTGGTCGGCCTAACTCAGCNAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACGCTGCATTNCTGCCTGCANCCAGTCCGGCGACATACGGNAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTANCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGAGCGTGCGCCAGAATGGCTGATTCTGTCTGTGTCATGGGNTTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACNTTATTGCGGAACTTACAACCGCTCAGGCNTTTGCTNCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTNCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAANCCTTACGCCNGACCACCGTTCCGCCGACCAGACTCTGCATANCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCT
+
''**&$*((%!&#)'+#!$!(!#*#!"#$#!"))*&)+(+((%$*$!&$$'"&"&+%)*%#+$*#!*"'("+(&&$&('')%*(*$%%*+#'$$!(!&!#&!+#'#+#'#')#$%#!#$(*)&)"$$(&("%&*("'##+*+)"*&')##'&$*())#+!($")'"&!'"()*"+"**+""""$+))!#('($!'!*#')*&*()"(#(!&"%"$()&#('("""*#&(+'*#&#(*(+$'%')&))"!&#)&$%*+$!*!(*"$*&$"$$&!+(*%')''&)((#&#*("(%)*+&*#%)*&$!$$#))($!%#''$)+&%&(&#$)+&*#(%+)+)'"#)'+)&))#&((!%'!$()%&#!&%%#$!!'#'$"#''$#!##$!!'+$(#)("+$(*!(#$(%#+#%!+#!++&$($&'#!%))""%"!'!''%%&!(#!*'*')"*$+&%$*#'!%'(#%&+(+("($'"+%'%%%(+(++(('+%*++*)"!)'%%&'$%#%+')#)'+"$')*"*'+&*)$*&""))"*"&*"("))("$*"(")&+&*###&!(&&%+)()("+"*+%%*!*+*(&$#)++)(%(+)$+*!"+$*$#++&&('%%'!!+%#&'&!""+&+%"($&!!%!*+*&&#&('$('!*(&'#%&$#!'*)%"%*($#''""$!$"$*#+"$)&+""#&(&)&*++)&")#)')*)!"*")')$'))'*)$++&+")$%')(%(&+%##*)+"!%!*#++$(#"!)(()$*&#'+$)"$(!$*('&!+$+$*+)#($#'*+"+'!(*""'#+""%+"#&')!("#$$)%(*"!#((!+$"(+)"%&%#+%)%##'"%#"(+##&)*%#($(#$*$%%"!("))'$"!%&"$''&)*($(*#&+!$)")*$$%&(('%%%())%(&#+!*%++!(!"!(++($!$+*%"
@r3109
NGTCTTTTTCCGTCACTCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACCGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCC
+
%8'&?5F=@5F;H>-68>GG(!DD;#G#/5>$-@>*E!&-E$8!F;?@"E!"<$!'E8>68,FG+B!%7=+-9?5<5E:5-H8.!;5$A$29+7";*D7H<H;$!(=6,71;%<1(1+)$,??%+;(5@ABEE$;?G+9+'(E8*CA(3199FF9,DB":84-*:A01<H(A0GE=&A2&/HC'?**/#G:H/6?D+,"#*%)DG)9+DA/G+:71;@/H2GGD
@r3110
TNCANGCNAANAGNGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCNCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTANATTNGGCGACAAAGAGACGCCGTTTGGCCTCNAATGGACGCNGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCANAANGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATACCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGNACAGCGTACAGTCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGTGAAAACGTAAAACCTACGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTGCATGACCGTGTGGCTTACCTGACCGCC
+
*#!$)$*$#+)''#++&+!%'%'$(%$'!!%%)#"&&+&'#"*('%+##&()%#%$&""'!%#")%((%%#&)*$$)(&#!(+"%)++(&!$&+$'"$*'#&+'+%()%($**&!*&+#!&$"#+#!+$+'!#*%''&!%*')#'*&#!*%!(*!**)%&#''&&'&#$'*%"%*"()%(%$**%#(%+%&'$'&)%(*$+)""+(#&!*"*$$)$!"!"&&"(+)$'#&**""!*'&#!(#$&'!!#!&$!+))!)(&#)#%#!&#&*")&#%+%"*$%%&+#&&'*"''!''!')%+**$!)))#")!$*#$*))$(**)%"$(!#*&+**+*$"%&*&($'%$$"*(&#((#'%%*'##"%"+*#('$**&!$("('"(&&)(#"$#*%$+$$!"'+##$+(%%!!$($('"%%&"*+#!+&)+%!'#'*%)''!%(($$*++++*&%#&!'!")""'$!&*+)*&&"+&#$(#+$($&#)+#$*&+*!(*+!$(*()(&&%!)+*)*&'#&&+!&'"("##+%'+%#(#'&!&'"%!"$%)*$!(%'""%+%#(
@r3111
AGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTCGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGNGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCCGAATCGTATGTGTAGAAAAATAAACAAACCCTAAACAATGAGTTGAAATTTAATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGANCTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGTACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATNCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTT
+
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
@r3112
CTGCTGTAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATCGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGTCCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGNACGTATGCCATCACCGCCGTGCAACATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGCGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCGGAAGTCACTNCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGNCGACGGCGGCGGCTGTTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCNGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCC
+
*%**&)%+$'')*''$#(%+&"'"#&"&#$$''&(#*"*+*'&'#))*!()("&%$+'#$&(+"$#&&(%(+''&!%#&%#'$&++&(+++&%)&!(("*('+%&&*"&+('$&!$(##)))'+&(+&&*($'#()$#%#&%*%+%$+$"#%!"*!'#!#!'(#(**)")+*('&%!"$$$)**"*#)'##)""(&#')+*%)&%!)'%##")#+#+$"')&'+'''*%+!&*!*"&#((&%&%&&#%*'($#'%'(!"&%!+*!!#"#&(*#"!+!!%!""(!*$'++**+*#)!$'!"!##"%!&+(%+*$+)!"&($&$'!)!!'(+$)"!#*+'()&!&+%%+)+$+)$!"'$!*%'!!"('"+%"%")(()#)'#"&"'%''*+$*((&)&#)&'#"#!%%"%+($&)*%#%'))&)&!!(+$)&(!+#$'"+("!)&!&&$$#'+)&$#$!)+*(*%&'"*%*)**!&"%"*!+!*#*%""*+**#)+#"#%$$"%%"(!%)##**%+%!#$*"#)''(!"*!*'&++(*$"%)+!#&(')#"!'+'%)*())#%'$(!$*!$"&(*#!)%&!#!*$%!"'!!*#"&)+$"#*(''"%#*+!%&#'$#$+$&%%($!"#"%&*(!&%#!($%##!((+#*!#$(#+#$&!&$*%#'(!***!*+##+(%#$"+!'+!"'$%(!#+#(#(*#+%'")&$$*+*"%&*%)%"(%&$$&)(&''$!*#%&#'"#$!&!*#"#%!'+"!'"!
@r3113
TCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGG
+
'?5+B%C,@91=)B"BCB$*60:/D!*'D1=/4D@%,1+:?.H1A*CD=+*-0
@r3114
GACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCTCGCAGGAGATGCTGATTANGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGNNCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGA
+
+###&'#!%(!!'"&'!(!*(("#$''!"#"$!%('#&'"$(($'!)"*%&#!!#)&*(*)'$)#+&$+(*(#%$&++)&*'&*)&%%!$"!*&$"(%$%)*'")"($$"$"!)"&"$)*)#%&&'+(+('!")#)*!"!#("+"('$*)&$%+*$*!*&+%"**"''(''(("&!!!"'*%!&!)"((&"%))(#!(+'*+')()'$'$&#'%')&$))&%)"#"*(*&%"!""*$&$"&!"+((+(#"#"!&)#)*)+
@r3115
TGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCCCTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAG
+
,+:6<%4#/1@6HF=)C2B"B+$+)"(H"$>HA()A@3A'3B,A<=;&737@@/?-+''*.!/E56?C!7=%H#.@)H!);)F+D?'C)>C>B(%(:*2:D8#<'*)502BF#%@?HC2)7=B0?80"
@r3116
ACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTNCCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAAC
+
6E328@)B)?6'>'"B4G0-8B>>711?%G=5216":)!<?:?97#E6<<(2'?)49#,<(BG$!<$18,.C:3+&&)3H0;,H-<$153$&C+9F0F:(>80/(C!''(9@$B93#;8<3!FF592E?)0H<;*A@@1$=G>G9*$$%3.D$1C*=7H:7!%/2%')/CC"1G(F68E>-2F0-0/76B7$(+E&AC70@)-C$5+29*591'13
@r3117
GTTTGCAATGGCGTACCTTCGCGNCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCG
+
7;"30BG+E8*$(12)&+=D$/G*54;*+)%;454F:-60357E?'0?9:,2"%#5<!*5,F$40<@!4>)A:D9C)0(-&.D#4-,*DA4"9?.?70H=>./6F#D;)?-7?0*C=0*"/<C%>F32&!G=6:8F5*DH3--8EG9G&59>-9D&3B?6=4+G/A:C-:$B,:256@+:8
@r3118
TTCCTTATAACNTTTACNAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCACTGCCTCCAAACGATACCTNTTAGCAATATTTAATAGCTTGAAATG
+
$!#*))+*&"($*+"!(()+'*%&++)#)&**$)+'&!!%%(&$%%$!(%"')+("%"$#"%%&"'!('%"!)$!(*($)'&%)'$!(+*%%'+*'+%+&**#$
@r3119
CATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCNGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACANCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCT
+
)==+"%95E!="G96?,D.3?F+5(G!9(;@$'!!:G!22E+A=470H*;&=0#/6&HE-/C")+*3.!86>A><6.E9CD?>9:!-;1<5,G64,52F-;A/?6B-EBC$/8(42(3'+$'G5&C@2)8;07.,>HB<1@0A(>76CFD21(5')GDG:"#-:<&'+;4A&CD7))1'/1FH<9'1>C":!&&B5&6/5$C*10)G+%8"=C>4%45!@#&404+-+:*%+"'B0.+#("!;@7/:+%A0E*)HE.6(G>F09<8.GG<85:8E=B'C#74G3!?($CGCFDEE?+2E7-*24<*6!1/=%7@BGHE#7D>9@!*?+A&9-:1H03+:&*)G7#:G:/DD9G2=?H?)..2C#<4599C9.FA*82F#4(6H/.-#A@H(C,:<?;E5?2B;65-
@r3120
ACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAAGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTNTTTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACTTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATACCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCATTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTGGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAAAAATTCGTAATCTT
+
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
@r3121
AGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTNTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATNATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGNTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAG
+
C/1G#D1B4/G!'&?<AC@G5<<E?*7?1%%01C=E&A*D<092G::9.B'E7',92A/B"2/9,DE-9(##*6(AA0+(!3B*)(<::-#+2)D4CD%65-)E.=!0AB,%%!;H?'3F@12(.;4=0%A;+;4>#<E,:231&$5&FA/*$6<D,5H)?5+>0-0-F>+G%2%;<""BG6@7=@,*-6%%G%$%B@9/6?%<@E$;>+<69";-,0?,(;1.F*7?.H#:36735.&)G;#D87-:!;13<496F(-7/3E/',&8F'H'6195;-3+@9%G'<D96:D@%:0;*/=$@D8;'///'<-1-=>D)8E5E7.4*6>*73&767$:)64!34D-F9>1>74B!"FH2-5C@B3A7+,20)2@2"(G0E8;FHH3B-$/>-.+AAH(7,3F2,(4(.E,:D(AC;9'7@AG!*FE<<C2?+;1+H"
@r3122
GGCTGGCTTTGTGGCTGTCTTCAACAGTGATGAGGCATCGTGGCATCTCGTTCAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGANGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGNAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAA
+
1%;9))F3@&.*+7>:2=*-'<@836BF**;(!9D+*!A-6H"E'-***6$/9CD!#3EF0/@-64<<B6H+25/<)*))(-@.FH?<!%1'%$!.4<.8$&'D1;=C,"3DBDF:347*>=)2"5?(/163.;G$#6@04@:2*&C$*D</+$D'.5%0.5?B-!#C88+6$!CD(#&7>'?;72<(::&50%8,#0=.3"(E*:,+>A0C@D)H,.GE'$0.G13264!1370!B#(;;:C74<H9B:+=G""!G;=D,,7;;2=1!FB;;D(/)3>A=<)8+C2:58DB7BEC<%.+EG%6,H""4C)831B$,D$*G=%?994>GB71!3A:4+E"-:&:<<<2?@!H3(
@r3123
GTGTAGCAATAATTGCAACTCATTCCNCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGANCTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGNAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGNACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAG
+
%>?C=A&E@;F9D1?,%5F+F=1;251DF"B,'<=31:=6E?%*64(D7-/4&6<??15>+BB.=(=0"AD>"=/+3A6&E+B*8E6;<&;G<6>E8:6B'$C&EE;+)29F:+)0HA.7#F+,.B/=F:9*2)',=&?%.3:G.5.885;:F86G50:GA)*:"%7&DB4FBB!$7H)?C!2;*?F7@AA*$?91/8-:(!;A>:)$<E<%$FB"C;&(;"73?&6=F3$=8/"E,FG:$6;.H)")#E9)F)>CA0F19',#9/A9.0):3$7(/56:&@A38>5=*<?;DCH+(62&"+A5*=4*814?/:D=-;B5GF%E<G,!#39E&%=%,@:+*(8@,>"B
@r3124
CGCATCTTNCCGTTTATGACNCGACGGTACACTTTGNGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGTGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATTGGCATTCGTGGAGGCCGTCGGTCGGGCGNGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATATCCGAATCCCATCTCGGCAAGNAGCTNCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGNGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGNACGACGTGTTCCTGAAGCGCCTGACGGCTCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCAGACCNCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGNTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGGCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCNNGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTA
+
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
@r3125
GNGGAGTACGGTCAGTACAGTGTCATCCTGCAGNTTGACGGTTTTCCACCATCGCACGCCGG
+
?1E,0'")-@5/(',4(1".=9<4?&B+>)BG;H>%*38%?.3%(3(:065$"0;7>(@&9&
@r3126
CTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGGCCGTCACGACATGGGATCCCGTGATGACCTCATTAAANACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGGTTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATCTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATATGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGNCAATCCACGTGGTGTAATTCCCT
+
:'53@84;("<9&6H4./<-10>H?;F87?8)30@8:4G8+;E/%"C)A@*HC-,0A30+.>%-7'>#)?632+#1#&%&!<382$72)/':2/C'<*GHD6D1:$5*F#''C;-9=E/;17;;51;*&D&F>9EE?;<B"#"=EB*C,=4*.;A5/D5@)))0%2"C+&)@,//4.85=%B,56E,5$;'5@:,+75!8(&0G=$CB&,,3(?7!A5%#451(+E:FB7)$1G%/6;7H&&+<!/1?7)1(540(6G004!&*.-474,,DGEEA5&<A<A;8C?7%68*F3+@-H(@4<6#E$D23+2$3$!@6#%423AF@*5D0&2E=>.A&>6')>'H5=/C2$:7CC";4E'&&.37$8!>8E7
@r3127
NTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACNGCCGCAGAAACTCTTCCAGGTCACCAGTGCGGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGNCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTNGATTTTGCTGTTTCAAGCTCAACACGCNGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTGCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCG
+
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
@r3128
AAANNAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAAT
+
)*(#!++'+"%")!+)!$&!$'""&!)#"$+"("+$)#"&%$*$(
@r3129
GCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCNAAGTGCANCCAGCTGGCGTTTGTACTCCAGCNTCTCATCTTTATGCGGCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCNGCCTCCTCCAGTACCGCGAACTGACTCTCCNCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCNTGAGCACTGTCTTCCTGACGATC
+
&+5&(E#.-5=A-7*@:!+B+<,#C"'#(64)&)&>D?C"6H*1C1%<7"%7:,=>.+#5/=(A1/=5?GA:A1,:44.(C:"3$C3@8H5@5,)56'G-B558%;G27,40?7:18@36@0A#&,+3C?/C3*:FH3-==055(GG4AD60:3A@.69>'E%6*C<**94/3)/0&)A5=%,.BF$'8#F+H@5:E,$HE"G+2)<FEG3$):#62<83A1<>=(E8)F,072E'*11<);:*&5#'3A7ED*("-ADDB653B#34B*$'226?1C$(-(:/1C-==<'!,D160H*%B@/892)@6,
@r3130
GGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGNCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAANATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGNGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACNGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACNCGCACCATTACGTCTGCNAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGCTACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAAC
+
C6*4;G;@B(G+3H-@#G78@75<,@";$.9C!H2(!G)H60,@:)8./;%CF<?&=0..+5<>)+?$97=A-10'-G:?(DCG$$A00G?E7$5.60,@6-1H/F&3:;,@9G920%1(%.%!%/&@<+'C@/&F9<2-A$;//?="(&HB'C,@*!33EE8,".-1"-.""*=8((H>C=.@F"..);+7%H74E(05>;H!'A@1C-439@A&108<E#")H'C.)<!<G!)F+":H69B!,#A&D%4?5HA#5>HG3"?D75?!D)7B5;@(C6740A:9*%D4*")/8$.$8E%%+19!'EGD*F.9.G3G/-@%F,3AF;:7'-&D'!.49G!'=9E?$2G?HC?)0H7,%5%;<-*EB42!/#!:2(5H7D('%1>%(D%37.G7)#)<2?F$@H$AD7G'?%H6>;A><9C@=3B("<?66")*2F36/H+;4+&>C8$!'4<#F>!(<>B>+&=;,*60!%5*>&G;BA(2!3B1*>4/#$*,400DG?;22-&/7(.C5,E8(").-2,AC8/A2?@#5)>D9&8"07!97#B87&;/@+=6(/(0<C&&5&1@):&EE'8>!3CB?.%B<,D$6A*0-#:=:A2D9'.<124,5.<3::(&!(%-F+H#4-$>3!1:DD5,=)C>!@1G2D+-8&A-1.#012=@?*9#CBFF171G*?D?9?)?F0E9:F!8/A&6&).#!:H#C(!!4.+##&77=!E(FGBD-=;2#A0-(?",8/1/*B-).'&FA$>"-;!E>C<9'!DB87*GF(;+G3!:%B7)&+=6%=1/=B2-*31".:(%@&=*"G:0;(?B,<A+7B<.07C*%!-.,'2;(15C;@,F4C7$7'=;B00EA=A41G0736>&D,4A>'%D)10>!F,!&(;3B)-5,)E8D@-C$*8!%>=@/">3D7C7-3D"B6+3FF?H@6
@r3131
AACAGTGACCCGGCTCATACCGCAANCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAG
+
-1*%C0<!<8+1,5E+&-@;/(4+5=!"$7A?'@F7#='C2CBE<8(52:.<239(1)67%HD7<"6*:28?4H*F7F/4E3A?/'(*"2'A=F(E
@r3132
TCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGAAATTCCGCATCAGTATGCGCATTGGCCCGCATGTTCNGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCNGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAANCTGTTCCATCGGGGTGATCCCGTTTTCCCTAAAAGCCAGAACCCACTGGCGACGGATTTCGTTNACTTCGTTCTGGTCANGGTTAGCCAGGCTCGCCGGGANAGTTGCCAGTAACTGGCAGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATGTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGANCCACCCCGTNAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGNTTGATTTCNAGTTGGGTCCACTTAT
+
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
@r3133
TGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACT
+
2D-H&?9.F%(C'A$8/H0?#/:/@DG0?/%@7'A(,,AEE*>F).#!0@G),39B;5G**+;%6228=58H+B$:5;.7*F,1<7(++8,>D1HG93%54"(&5!4;7":8,92.)61F:<.F98$>)>,?2+8D(=+0-;/5)#
@r3134
TGAGCCATTGGTAAAACCTTCCANGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCCTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAANTCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATNTCTATGA
+
*EG1!=>$GD,E+8<HA'%7(?%/<6>-:H#,6>/-".4,0$+>?-)48&"#<.).C/E;4,(,50$:-%$F;&'"G</#-<71<!,)$!C/:.F='9G)H+('#'=%4(#;+1!"97E>1<AA)1.%;63>$D%>#30+$($.E$354GAC5C724FF,%!H8?9-5<G"GD)+F/0G5$EGG*2C:9/9+&C;!HC:F7#;<!@/1>$:+HG@(9$+2E,#GDG1!=$&B>E"-#B$E.E,"'(*&.E""$#B!B+78/HCH*+2#C=43BE;&0@@!A.8%!2G)F2?5B<#E1=-3F1:0H82D%%4F7#@1<:$,@<+;H5/<F1(-1C?3<1D".2H7,5$:6<1-E%<@,)1F80+H7(7=2)C0=1.
@r3135
TAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAGAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCNAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAACCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATG
+
";?:FC@-)B"#(3)F(2H3A-C5?<$H+E;.(2.EA/!=BBF2.D;B%G*%28(DF6!7@%;G*;6:>9#48C>""<E7@@D1$,.E?<.,<@"B9(-$A-,99>5E(;(@@)D23$HD<&#"G6$G$#)'F9!?02.&*8639=?+B<!HCF6D'*=G11C(?FC>$9G3&62G<&>C1.:://<H'-=(B<+>:!;+"F0=8!<8<08/#C&*)"4$E(DC,/=F0'-3%9+)#'@,7"7&$$H%G>&9DG6!3&9DDB(<E'.!$5@-#6/$#E@FG.B/,$B>;=C2:<=1%(/"%,/4C/C=E%-/3,+#F5=E;D$)&:+#8%,%!F2.'8$2",<)..--$64/H2/F+6,"44HHC));"6DA9>260<E,>6(76!#D+A@E0AGH1;9&'GC@"<::25"%G$391$EEG@$0)!AHG2H++G!F1(&@,>7DBA$H(C,-8C@=(:=@>?62F?5C
@r3136
GCGGCGGCTACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCG
+
3E?,'+9%'(,$E<51A8'C?,>&><C+B%&B<@@-76&#$/(-F3,28:348*?.6&)C010)8%F.7F)FD*//;<!7&(97*$7<.&7;.G/HH'4F6$88C@03G29E%*5$%CHD+,3'2G/D9B$.
@r3137
CGGCACGATNTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCA
+
-,D">:-E9!H-4A3@ED/,:0E>GB03>!>!.A9AH$EA!>;<(
@r3138
ATCCCAATGATTCNTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGNCATTTGTTTTGGTAANGAGAAAAGTTTTTCCATCGATTTAATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAAT
+
<(442$>H,"B3E&$5/B"8&>8)0+#:+3G4*E0BA(/+!-/F)F+E-!$.4<(10?/'D%0E;B-@*C&9>0C8&&H.*(*<DBE1<5<1(30/,*!:;#,%4!?/')0.0'C1E9#4&,)07)%%110FG09;=107>#;F$!!457C$C/&G6E65@-A?0+D#+2BDE?+$F?FB&*09(B
@r3139
CTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGNCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTC
+
G&2?&&?F8<#'D.%C@C(A@<B06$-!&9B63-$?)*(""AD,4//"2C#.A)+.5:.,%'8$@7A.%.#D="G4A6?:-%/)G@/FG(-2@0*7
@r3140
CAAATATTNNGCATNACTCAGAACAAGAGCCGGTATCGAATCTTCTAGCTCGTACCATGTCCTGATACAGGGCTTGATAANCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTANATAATCTC
+
&'*'*'$&"")&&%#$(+)*$+*'%+"*+!)!#&&'&(*"!+"'!+#+!('*(!$&'!!*!+%$'+'##()'+#(')&$")*!!"!++)+&&&#"++)&"&")'++$+'!%!"+$+&!+$*#($*%+!&+&&"$*&(!%"'"
@r3141
TTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGNCNTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGGGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGNTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGA
+
*G:#;H;:9+<@B=!:C);+(>:F6491,1,?EBG9A97,C;/56"?,5?@;-GD52'=HFAC>G'6H#>1#*1!&7-!<A4>+09A<FH'4E#'H3E!DF4>;24%*C;E$"#HD3=43HF-;>)B2&*8/5B=-:'2#E:)92A,.,>=DC@('65*?"?B@BA01F0'!+2-02?%/>*;9147?";"2*C@$64%9;>F!-F--%FBD5A$.#/C5,A&3.61DH.3*B8"/F4(,74,9";%62D<F)"=GD4,G@8,#8H"7/)<F@"G";%=-E+"&'(:6;587@=.94;C6!42G/H98>D;0@4!<F*!/D!
@r3142
TGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTNTAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTCAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACGGNGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTNCTCGGCGATGCGCTGTATGNCGGTATGGAACGGGCAGACGCTGACGTTCTTGCAGGACCGACCGTCGGATAANACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGNCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACNCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTG
+
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
@r3143
GAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAANTCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACGCAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACAGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTNCTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACG
+
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
@r3144
GTNAANNNGNGNGCNGAAGNNNNCCGNGNACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGCATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGCGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATNGTTGCCCAGG
+
''!'#$*$#!%$*#!'')*"!$"(*(!)#+("'($)*&#'($''$"&&$('&&***#+#$!!)+$(&))"**+++(%((((%+%''#%!)')&''!+!*)+$*&(+(*(%)!!'**!!)&$(('%!$)'!'!*))"(&&!(*('!(')'###*!#*&')()!"""*'&#+!'++#&")"!*&!&"%*$"&!*&"(&(!%%"#((")#)#)"$#'#+"'*!)"($+'*("(%!+&+()$&*#**"%!"%+&(!("%+$+%!&'*#'%$)*$&&+$'+%%%%#("!*(")#&"#*$"'*)%(')*#%")"(!)"(!)#%&$"*)$#+#%(&%&"!&(&!%")%"()'%+!!*(%&%&'&&!"*)$)#%'#"&$+#%+#+$&+$*'%'+$"(##$(+**!++'"&(#%($&!'$+&%"'#%)+%'"+&(!))'$+)!(%$+#&+*#"&'"()!($+%!%+
@r3145
TTGGTNGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCAC
+
29=FH"%!'#1&!7:C7,2:H'#:087:84<E:85H'C4;5,1*@,4!F2<D0C,.6C9*AG,*9)9$,02D-B(#,B
@r3146
TTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGANATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTNTCCAGTTTGTTTATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGCCATCAATTTGTTCGTCATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTANTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCNGCCTCACTTCTGCTATTTCGCAGGTCTTTNAGTTTCTGNTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGATTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCCCACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTTCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCCTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTNATCGTTTTTA
+
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
@r3147
CCTGNTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCNTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTNTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCGGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACAAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCNTGCGATCCCTTCTG
+
())$"(+'""+**"!'&'+&"*!&+$&!("!%%%)*%+%"'$##$)''$#"'##"%#)%&"'+%#$''#**$"'!&+'''&(#+#!&$"$"*#$#'$!%(%$)$&*$+(!##+)("""!"*(&&+'+&%#+'")#"%!!$*#!&('!!('%%+!'#%+$$"%$!&'""&$")#"("#$""#!#*(+&""+*'"+%"+*(%)(&"&"#"%!%*"(#%(%&#%$&)'+!'!)$$)*%(*%))%(#%&+()+#)*#($%!((&!!+)+(%''#$#()#'#(+))%##*!%"'(")%&(%$*#$'!$"!#+'+'$%))%*
@r3148
GGGCGCTGTATGTCATCGGCNAGTACTGCGACNAGTCAGTGCCGGACGGCTTTGGCGGNACGGAGCCGCGCATCACCTGTAATGCGTANCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGG
+
;-@G'D?AG<@B"#-@B9=8B*FG5-A+:)5/,=D5.#"0*9!3D+8741<:.)D%G7/B)H/0,/+@5B$)D"!??08<11?37(8@''0;/9%+#)F*9@7=-9(17>;;79)*1),0;)#'6B:2F0:)A(:24/>B%0>:.EGFB#2=93=:
@r3149
AAGGGCCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATNGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAG
+
48H;B;E+@*0388D&=G;9-+&.2=4#CEC1'A**1/4C<=!<.&?.@<$57:G+;(B*8-*"=B=4.@,CC&4;H5'HB2H=1%%='6F=5G1#:)7<0476.;&@D-&G/900473A32=>C4<!;A:8!*19*<$(H!B0@"C<>"6?/69)D7A;<$5
@r3150
TATTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTNATTGCNGGCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACNGNCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAGCCCGGCCTCAGCGCCGGGTNTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTG
+
'$5%9A(/#4$HH*2F6FD=1G03)0HE90;16E1&-#4:&6.5&F6@6(HE;E4A-59=2<A<F))85;?#6.9$!(6#/#"E&4'.D"*.8'8&?CA8%6.E0<=AGH%9(5.:6=$+(+32(FF-0..E1<G(:GE7'()-A-<;7-%G'GD<%$3*8&6>72/1)B5(/0HC<4<G),D.G'5'>A/8#;"%&1@@3=;/)3-.:G+"$ECC956>=2*=>54&(GD.A?A=&B-@7?),"'="1$$D+.DE8=,;;,6?1@1(;61;;#@,=0)55+5!-@+E!E3#&'!H)/*;$D0"AF3E0-06"75-0#,2:<&%E'%4")%(G"F?0%<6>9""8/A4)&==GC#*99;1B;#"=H,;**?HC/GH*2?7F;(3$B;A@HB/('!>!</)%'?;
@r3151
ACCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGC
+
&8?!'A8"&:@&FAG#-.&0;2H1>B,3*'H.G-0F%.?/,$>:!%D39E
@r3152
GGAGGGGAATATCAGAACTGGAACGGCACAGCCTGCGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAANCCTGATGCAGGTANCCAGT
+
,2E)A0;.9;E8%H,>&0%E'.FGF%#EEC.8//&:)A.-G-3@(&(:5:731,C?H58?3A2DB"F5,675EC;-A1"/;6/0@9>&-C51?7H%74F'3)A07-4:F=5+5&,,B
@r3153
CGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATA
+
C>3-E0$B&3H!=C1AH%7,+'D>38D3#H+7"880-1FE*9D-+0GG0G$@2!6-)47@60@C+45"$9$.*-%3!,4FD/H2'@-E="59E!E-"C0
@r3154
TCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATGGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCNGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAAATTTGGCTGCATCGACAGTTNTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATNTAATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAA
+
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
@r3155
ATTCACTCGTTGGAATGANCACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGC
+
@8)09EB#;?%":<6>B62HB)21H'+4436@7=B'@-0>75E:AC$6:25:F>3H'?-*)),1&5G(?:.EAC
@r3156
GCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTNACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTAT
+
C20/+&6'D:G3.-;C.0E=#.=<86=@HE35;85(?C7C$&29G85=?3##5A"=(;GBEH840F7D/5*A+05D<5#*2*/7?G3ADF3(60;!90>@<!/8@&1A!!#-;@>?*825B<!6&A9F9CH.H2#?2'&57D.9G8!%=B93.?&(-6'C*?,-&,;->$<7C/'/B<G)C(DC*EF3A4G
@r3157
TCCCTCAAANCGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCCCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTNGTCAGAGCATTCTGGCGAATCCTCTNACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAANACCTGACCGCCGCAGAGTGGATGTTTNACATGGTGAAGACTATCGCNCCATGANCCAGAAAACCGAATTTTCCT
+
#?FG44.3;&*E0&"6E'5259%<)>(D">?%D$8=*EE8H3=$('@2F?75,2DA*/#$%;%@%7>;%>1;0,F(1"'9.##,6AD>(9,>.0=./F"25:5A4#684;5=:D0,&4>C="0<0E<4>">F'@)85F57@>2:2@#B<+6.?A&?ED$911,"9./9*34!''09))!D#4%3C,'+8.-,03A$!9E*B<(*;3)E*:<>4?)&)3-A>>=<$"227>+:G,:7,(C8>*0!7>,-2,C-&+8+E%6:06.@=&6+C9F:,BA<G#F+)))2/40,>49D!B@'@H0&$'6:'
@r3158
ATTCCGGACAGTACGTGGAAAACGGCNTCAAAAAGAACTTC
+
0)4G5591<@&>2$F&B'9A7.8$+'A4&$-,B!501;*54
@r3159
TTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCNTCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTACTGTATTGTCTCAGGAACAGGATGGAATTAAGTCNCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAG
+
%/C0C4&+G'?*5%)H<@=&.1"<C595?670/>9(&EE1>#HEA<A/9.4H6$7/90.)+>=?H!@+33)4C)#=?6C-4$0E=<2-=F?A)23.54,3H40A13<CCD6HFC7E9E@:;=?74?803(%5'.*F:+&-+!HBG*@EF/B),B@4A@7G4:!%'88HE?1=$6G'-H(B;EA'-='+6)@(F,,'/C-:DG9,!H;7+#1=F.:!5+E7+%EB#A0AG*$$E.0HF5G08C;,.+/%'A=D;5%GA$???F6A4B7A)<.(!-4;7/2&#42;(C!F'D/1G%D$#.>'=77H@%'4*EA<D2BD@4C7!,/&-4-2#%&39ED>C?D"9;>?!1?E>"/49H<2"';DA),A#9!0G@>#!F.;D*4G*74;=#;..9AGH9)B.'@13=%-(%#;=7=?.#-*#?27713:%,*@H6+:$/-G?+BF
@r3160
GTAAGCACTTATTCATTAATAGCTAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGANAAAGTGCTCCCGGATTCAGTGATTTAACT
+
1C'+.E9?('%"8>C)!,G+"+F-?AE@!(EH1G/'&4<9.H*92(C3(*0(">674/AC8@&$>*2%>97:'(C!(1?."HF>B-'&9>:+8-%0&066C(8051!/-C0>6%=(/09H$D:?#(+='3$8=%A0-2?C+'92+"EB1#6AB.?<1>G)82@(5?H':F=:#(%3"1!E85C+#3>A,",$G*:E=$DE;'#G!%43,6"A,8$*:&=>!9'/&'(<%,'5(C8E1;&$,*8%G=G6%2*,E%9)#<@/H@>GHF-3,35-%8@"/(*1()!/0>641GH%$H,&;=@/)5H"7(F>!0<7<,@<;;7.:-!>
@r3161
TATTTTCAGGACACAACCACAAGCCTCTGAGAATCAACAGTGATAATT
+
5,91!9$&A;$=:)4"$#!+"H;DE<'$*+#G64";5-69>3,3'@"+
@r3162
GCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGTTGGAT
+
5H*$F(*?>B??+-+1E#5<HC(A./$.B!!"D/>D8!-)$:/<+
@r3163
AACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATG
+
<H<51=9>5D-+/#;::;<E0>"'+=%B/B7#=5)51<E+.!;0208A<9;!CD+D%H><0@-+0AGG:)=G<"%9:'#4*&>>:.&%<18
@r3164
CGACGGCGATGGCTCGCCAGTTCCACAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTNTGATGATCAGNCCCGCC
+
';<%5@!(,..B&6/#;B&*"B.D4%A:H3D(84?-A$-$3(B)%3<D(AC#.3%C,(010;9=227,>3946F.3,*?G>22/64&>!30#B,5E/-&%5C%C=;<E@E+H$96<*3:A7=!D+A$F+*$&$D3,$>#=!G1%
@r3165
GAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCCCTACTGGCTGGTTACCAACCNGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCG
+
6;A<AA;2-&<>)2%18E&<E.>:/'@*!F#!1G97A6#FH+DG66#5&D70-!0,?/:=+)F-<5CE")<C)HHHE05C((=7#9AB995#F+;$B-!1-3/$D)/#6D&5G1&G6&5=5>'
@r3166
AATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCTGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAGGGCTTCACCGGTCATGGTG
+
>>%H=/<G<'0(D!4#3,+3H/AB,+.(@H0(ED4:&)E='"1*/+&:4H1-H199#1D,B)9D'F&G'&-E=>%1<3'26=:"/?5#2AF'%'3???:?75!=(6G=%>.*/59?FB(C;;!?CG02-#7'=&3?6!E-%H6$3D$?@5+!0*!?'F07;&264E28;-3H$-(A=;-:#/D,B%B*&B"$8(69+$1915@/.D.>24++%2E;:.H+B62%#?C=/-;2$@&A9G<*FD>:7)
@r3167
CACTGCTNATTAATATACTTCTGGGCTCCTTCCAGTTGTTTTTGCATAGTGATCA
+
?$'(/'B*?,@65F7$';0"D,5F"'BA4F)2D6?='=*079%.-4/5;!:4F#0
@r3168
AAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCG
+
B8"HGH)%"@0;CAB?5(A6&';&52>.!G#C##=&F4:(G)A@G<9FG;@!;/0F1-2-#!H4.D5C-F>*,B<A,90
@r3169
NGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCAT
+
$A6";*5'$G6FE1A%H14E@-D=FD*,GAG*F&17%>4?#
@r3170
CTTNATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAANAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATANGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTNTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGAT
+
%&"!%*'+*%"*)!)%!%()'!$$(&"*!#$"'%"(#)#)'!$&%&$'+*+"#*"+)+!##&(*)!!''**$'+'($'$&)$%"%$*#()!("(*!$''&&!%$"'&*+''!(%("#)#$(+$$&++"(+&"#'+!(%$*$*'+#()&"+'))$"&&+!++'%&$")%!!($$*'$*!%(*%!#%#"+&%(($#($!#%)%(*+%"'&%"#')+!((+&"+)$*+)+(!%*#+&$)**+#*&)%'$'#)"+")(*#&'+!%$)'$(!!#!("(##("+*$''#%&$&!!(!*)"$)"+((%$)$+($"*))(!#+&+"$"((%"+)&"!(&)(&"$#!'#$+((($((""*#(!!""*##%*'"&$&$%$)!%"*$++!"+*+!&((!)'##
@r3171
ATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCAC
+
AG)*!;+.E(>&#?(>&$4,(1!2H7;>>?:"FH13A$/#,H
@r3172
GACGGAACGTTNAAACCGGCATACAGCAACAACATGGCCTGGTG
+
0."A*#!%?;.<+9FE6*3#=%;&H,;*%G7**,::0%-(0@0F
@r3173
CNNGGCTGANNANGCTNGNNACCGGGGCTGCNGNNTANAGCNGTNNGNNCNNTCTTGATGCCG
+
'!#($%"($'(!$)#$"*!%(%$)&*%)*))$%$")*'&#*$))!"*('')!%!+&#+**)#+
@r3174
ACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATNGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTNTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCNCGTTCAGATAGAGCCACNGNTGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAANAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAANGCTGAGATAGCTGAAGAGATGACATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGNAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTAAATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGGCATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGNAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATNTGACATCGGTAGTTATTGTCTATGCCCTTNGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAA
+
2?/D0!B.;F=$0@$D&EH9??8E<#0E<$8,,"EA;","+F22=+/'*#/*,G->EC).@</4#&.%@C+$5+C>EF!H@$H=D68H)G;:<5:B1+G-E%B-E,B(()'79-/9';E(-F71#A&%G>HC)7<4((8=$F2%B-G,(=,3B7.E-$D4B!$#707,=3#A#>6-D?&4:&1A;-8B<4<.9G(HD47G4@:7>>B6B0!;F52-2<9AEBBEAH/G;;3&G4A01!''F!,F?E;;G+F6;D'<H$=(GHC/2;4H,65BA%?1/3:>=7><>"067?8#A$1;.B#&,#C"4&@50(%2!F87*+?=G):-#0=F##)5H&"0-1<06(=93E:0)>"::E.$203/3>4/</8&<D@0:EE)&<02-1;//<&G*"&61G73.:D765:C7@.1B+C?H33"0/-0'F#@42-698F>D(>::%")(30A=9*?G4/9C@!"FC2(E,7@B:7$E(FGF:>3@+)@;"F@73E!G"(32>5>B?DD<7?"A5A,H=+F!!;8*83GF0/4-D8"/A8$'B;D@0BEDF@+GB'!(:=8&+5$70C)B&A)/33GC5H<*7<%@#$9G107122.1E!:"B+5CAA!,'88:4A0894(<*21-;B&+(5(4A.((;77(7=-263%3("3C1(B$//@F3'&?>"F=C1)<4.9'D7*':4:/0<+1%<-AC-A1<?,.!;:8DC=>3;D.$,@$,A%=:!)##68D,%/BF$*('./7%?=3*(H?#0(&078C"F;,A(3<A'."1H3*?E9&3%21H%<68>A8CG!C@/F;G(';,.:&.7=->!/AC:1C$!?#=@./-'"#>D3(B:/A>E<=EB?D6,<-15*G"&#+'>F9=!?F'&DG2?,"1A"E#F/+A0+F=F.A58@CH%)$@2B3*3)B.309*=1!3D5#6($C-:!1"6,#C::?=0*?$*'0B9HE9-0!7:&;5B/<3<E'.?5883:4-<!E$";4D11;G?+*<B90.*4E<C/CF.D-7-B,C/-&8D0'6;5D@+@55<,3>4*A61<%G#<6.-0<**<9@$&.#-C(.$B##85786&(>,1."---D?+*D/&>'<1C;F=&/##?CD3-C4)25=?:>GG"?6*58>08F%%C9?<<+#<@49"%5$C'?A4H443)!0G0>'G&HB>0>7F<0E@24(,5/@8?8')=)A:@3>HE8='05;:H*225F))4$:"$9<AH>)":*$H)'60.A-4#&+G2C6*?5BA*B@CD('/?)A(30%@*A9)E6#"3$C-%H@D9G!<4/!3%CF!)&');(4GB?<
@r3175
AAAGATAGAAAATTACGACGCTTATCGGAAGTGTACGNATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTACCCAATTCCTAGG
+
B!<?C(3*2%0%43DC7/4&AF+'2*@H!B)>/@>%F05?+7'!<0@2>/?.?#64<64%:4(-3:F!A#>/H,,DG,99H&#*1D#(E(680.@$'383+3H=
@r3176
CAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTG
+
=.#$?91H'D'C(/<=0!HD%3/H%.%+0'75E)F8"F=(";E9":#(:0#'85H(5B:68D789<HG4"$:,.43D'5<E=,(BC!%!0-@4'54
@r3177
GTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTNAGGAATTATTACTATGTA
+
-?4D@3@-B?2::6$5$2@>A)29-BE0%6;4E5?4FF(A(9=$CAH=?G/!(?G7EG4#,2$(D6HAB#&!C:'%DCH85G6?D34'E!"/0H=C,06$+9A9D5G;)>FDH,+81372'-,.:2&"C/0$!-(@2E7DFF52?-)F!E+108.#-C
@r3178
TTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGNGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACNATGNAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTGATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGAAGTNGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGGANGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAA
+
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
@r3179
GGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATNACCGTGTATGANGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCC
+
:HB?2D*H/E2'/'BH1<>$GG?E/H-!G#9:6E&672'G#$6$B)@%#1"58$;463*->E9&3#:F-<B&6=:%%)<=D>,H8=8.45A(1):8AFB<"3$E:E5FF-=25?A)F?-7$,$8;+'5B#%>5HA;"G?/F0E:F=GD05>8;+&9=4G,00@$-3,-#H,CE%>30>D@8%7+5?AGG/(6)'G>
@r3180
GGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGNTGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGG
+
F<)%875,8ED*04$75"1D"((;<(AG3()G5:/3%8=!8/,'A*(B+$&BG8()(D-D(9"'6(@'-D89"&9@5"A>%4F.D(8,.7;$.@D$1C=>27=),H0-<:(H<A8*A'&9@=%G=),<D(9'
@r3181
TGTTGACCTTGCCTGCAGCAACGCCGTTCATGGTGATGGTCATACCANTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGNTGGAAGGCCACGGTCNGCGTGGTGCTCTG
+
'+)++&$(%#+*'$&(+'#"!*&("&)$%"#*(#$$'(*)'%)((++#"+)++'"#&(#!#&$"##+*#)+%$#"&"&%#$)*&%'&(*)#&&*($!+%(("(++$)%$*%##"%!"'*!)#)+&"#*&*(*'%$)!'+'($)(&%(+
@r3182
TATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTANTTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGNCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAG
+
6;/":$22"B4<3'>F*;CB>'0(1C/C%8>;?*@5*/&GH)"0?G36&)"8857GH9-$@)-AC9,=&A*2<C-=F#:-4!E=D/E19B=;F!4C@HF)@533:C2>.$+>:1?&@>:%E)$(4DH;91@GAG"3,/7(1.5#"@BD&)<=44FH?2.'"->$(5AG&*EH*H7"75?;1,+53>#/,GE#<.G"#+8*471:>G12=.)G<$$!>AB:>EA!3G8+E0"%=>>G-)6+/H6#H#&.&9C!-883<:D$3>?H'5G./=F"/-=/C%+@05B*3$4G,94+<&'#21/7'AE9:7!=):,%C;:
@r3183
AGGCCGGAGCCAAAGACCGCCGNTGAATGGGCGGATGCTAATTAGTATCTCCCGNAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGGGGGCCATNATGANTGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGTGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTTCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGCGCAGCCAGTGAATCCNCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGNGACGCCGTTTGGCCTCAAATGGA
+
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
@r3184
TNNNNNNCNNGNNNACCNTNNNGNANTNTGCTNGANNTTCNNNGNNNAGCGNANNNGNNANAACCCTTANANCNNTNNCTTNNGGNNNCNCTNNNGGNCCNNNTGGTGNCNCGNCNACNCCNNNACCCANGGNNGNNNNNCNNNNNTCGTNNACNNNNCANCNNNGAGGNTCCGNGTACNNNNNANNNGCNAGGCNGTNNGTGATGCNTNNTTNTNNTNNNGNTNN
+
$$!!!$#""!$!$!$#!!!#$!#$"!$$#""""#"$$$!$!#"""""$#$"!""$#$!!$!#"$""!$"!$$#"$!#!!#$!!#!"!!$"#!"!"#!""#$"#"""#"#$"$$!#!$#$$$!""$$###"$$$#"#"$$!!!#"$!#$"$!!""###$$#!$$!$$#""!$#"$#"#"!!!$!!$!!!"#"#!!!#"!!!"#$###!$#!$#$""#$#"#!"##""
@r3185
ATCGTCTGCCTGTCATGNGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAANAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATCCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGNTGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACTGGCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTA
+
,18A#@+C3%2'*;FF/,51%BB+8;&@2H;,!-15($+GD.5@3C#DF/7!9C*?*,3B1(67B+%6G&*7B7$-./1@6!>+-A2+&,H'3+65)!A"96?B<F(((96"'#?$A77E3:<#1:H#%B,44:+G*8/C"-H')1A3C<.<'C>B>.G6@E!00?A1!(5=*F;C7.3<<7,9(7'9A513/#E)"7C=?G&.!@7*$F-<D21D+F"+,:2G(:%.+3:68-#H*%"FH5E"E!-4967+E#@%1>%"/(;..:8H&94.4G4=30'1-+93:(ADGC)5&4B#"8CDHG:B30E"/2%860H>FG*GB<+,+F7<&"G()E#G2=8!-,-6,F5C;$5+G-5)!><>C!'?'(1?2%1@&6;5,"0GF0*/(8&#:C'498:,&!#!
@r3186
CCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAANTGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGG
+
A8<+0@7:*/A;!"93+))$.)0-26!;7AE5<C'2D);.A.(@#A@6:G+A<:F$E%5*,/A!7)&E*5):2$9*2GH?<0/2:72-60$#C+>#/3.3..#"0-1,0E&82+-(9-98@D(#'
@r3187
NCNNNNCGNTTNNCNAATGCCAGAANNNACTGNTGCACNGGCNGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTTAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCNATTTCAGCATCCCTTTCTGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCCCCGCCTCGCNGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTNTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGANAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAANTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAACCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTCCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTNTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCNGAAACTGCTG
+
!'(!$&###)"!&*!&&&"$'!'%$!('$($&('***!%*%+"$&'(*&+(*)%'++"(%+$%)$)!%$#!(%(+%#+*&$'&!!+)$(!+#)+(%&"#%#)$)('&*'(!"*%"!+$""#$&&&*$#*""(&%"&%!!#("$$(&%$()(#)&+&*$''*"#(%'+&#%&+'&*%+"#''(''$!('**$!#*#(#$!++!)"*'$((*&'))#)&''#*)$!*"#%'!"%+$(+&(+#%"#'(%!&*#!%#&!"&*$(%#(+)(%'$&!()(!'('!))($*$)*)*&!(!''($!$#&$+*#(#!%#*+$+(+%''*+&+(#**(!&!#)*'*$"(#)#()#$(**$)%"#$%"$"$!#*(&''!$"''%"!'*&+)*&*$"&'(!%')*'*#"$+#!!!##%+#*'(#(&'*#$&&*+"#"(*"!"%#+'"#)#")+(+*#%&&'((%$)%((*#!$*$*"!'$)*&#)'%)&&)'%%'&%++*$)&#!"*(%#&()"!(%+#+('!+(#((*'(#*!##$!+""&!#*"$%**(*(%('#!++$#&&***##$%#'"$*!'&+"#%'(*)++'(#(")$&)%'%)(&(%*)&"%+")"%!#($'+"#$'"(#+&)%&+!*'%#+*$$&#%(%!(%$**&&$'"+'#%#%%#&*'"(""++(##'!'"*$#)$$#"!"+&&!&*(''!(*$)**#($#*$(&(+#$($""%'+#*!!+'"%"%&+*$!*"($#!)&('!"$%'*$"'!)**&''#'&#+")*+'$&%))%*)+!'(!%)%+$%&*&'((!(($#$)'"*#$)*%!%*%(&')+$+!(#!!$$!)'$!)+"(#$$("$%$#$'$!*$!($$!'*+!*)+%"%*+()''!%#*'%!%!#*%"$*#+'%$"!%&#&((!$$"#*+#*&!%#*+(!!*'"+#*%#+"(*%$'"&"&(
@r3188
TGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCCGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGANGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGNCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTTTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGNCCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTNAGGAGAAATAGGTGTTCTGCTTACCGTTA
+
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
@r3189
GTATCTCGTGCGGNACGCTCACGTCTGCNCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTNGTTCCGTATCGCGTCGAACTGANTAGCCGCATNGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACNATCGAAGAGTGCAAGGCTATCAAGGCAGAGTACCAACTGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTNAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAGAATGCACGCCATCGTCAACGACATTCTCATGGTNCATCGCGGATGGAGTGAAAGAGATGCNCCATTACGNAAAAATTGATGGCAGC
+
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
@r3190
CTNNNCGTCNGGGNNNNTATANATTTNNGANNNAATGNAGGCNATTNATCNNNCTCGCTNGTTNGNNNANNCTNTNGNNTGGNGTGGNGGNNNNNTNNGGCNNCNTNTTNCNGNNTNCNNGANGNNAAGCCNNCCNNGNTGANGTNNGNGNNTANTCATTCNNTNNTCATCNNNCACCNANGGNTNCTCCTNNNCANANAAGNACCNNCNNGNNNCNNNNGCCGCNNNNNCNNNNANNTGANCNNNCTCNGNNNTNANANCNCGGGANTNCNNGNTCNTNNTCNCNTTGCTCCNNNCATGCATCGNGANNGTANNGANTNNGNCCNNTNCNNTCCTNNCGGCCTNNTANNNNCNNTCNTANTAACNGTNATCNNCTGAGNAGNNCNCNNTNGAATANCGNGNCTNNTTNNNCCNNNGACNNNTNNNNNGGGANNATNNGNNNANCNNTGCGNGGTCNTCCNACNGANCGNTTNGNNCGNNNNNNANNGNATNNTNCNATANTNCTGGACNGTCGCNNTNNNNNTCNTGGNNNGNNTTNNTNNGTNTGNTGGCNTNC
+
$$$###$$"!!!!$#$!##$##"##$#!"$$$!##$#""$!$#!!!!"##$$#!$!"$$##$!!$$"##!""!!$#$#$#""!$!$"!#"##!#!$"##"$!"$""!"#$$###$!!$!!!$!$#"$!$"!$##!!$$!$#!##"#"#$!!###!"#"$"!!#$$!#"#$##!!$$!$#!!##$#$$$###""#$$"$$#""$!$$$$#"!"$!!""!!$"!$!#""!$!$!##!""#$#"#!"""$"#""!""""$"$"$!$#$"""$"$""$###$$$!#$$#$##!!"$"!"!#$!#####!"$$!"#""!"#$""!$"#"#!$"#$$$"#"$#!!"#$##"!"#"#"#$####!$$$$!$$$$#!$$$#$#!##"$"""!!#$$"#$$""#$!!$#""$$"$$#!""$!!!$$#""!"##!!!!##!!!#""#!#!!!"#$"!!"!$!"#""$#$$""#$$##!!$"##$!#""""$""!"#""!"#"!$"#"#$"""!!#$$#$#$"$$$#!#!#$"##"$!#"!!!$####$$$$!"$#!##$##!""##
@r3191
TTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGNCGACACGTTCAGCCAGCTTCCTAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAATCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGNTCCTGAAACTCAACATCGTCATCA
+
1/;:A/2%&2-@:4<B<%,D6'4B+//7"(F=21G#;$(*%C.;H1/,G?48;8AE@A-5&,-'58DF#@4D.-H/31-:?DG4/<9E>0B%G,4G%)#9&.6.+EF@D6*$60#0E-E"G"8=F8,7"&5<+1=/!91-D?-6=F+.C"6%D<7"@EA!002*;=6G/%A0F(+(F&6")6/F4=9/:5DH<*88#H#A>:&(CF14H,#38
@r3192
TTGAAGACCAACGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACNCGTTATTTATTTCTGAACTCGGTCCGTTA
+
@,/--.$&H)<=<!@=(?&CF3,D07;(-0A<,$?'6:+0=E=,020.6!!,?F)(-%H'2@CE5)%)3E:9*&"-+
@r3193
GNTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCNGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGC
+
B*1C=(:?2735-3:%-/=1=C!ED1G$7(9@$&*)$=F$(=/$'=B"+*76>4;H5?G+DF>">2,?"<38+FF;A/E&.A@#/?E@H53B="-)#*772&+1%D#2:/4H=)-<A5F=%.:**/+<*1$>FG6C%=.7D+H:1&"+2$#!2#2!&H46E%'26<@!/614@*+)4#">H"75?-G/9377(<84;9&
@r3194
GTAAAAACACNTGACCGCTATNCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTAAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGTAGCCTGTTGGTGCGGTCANGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTNGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTCCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAACACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTNTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCNTGTGTTAATGGTTTCTTTTTTGTGCTCNTACGTTCAATCTATCACCGCAAGGGATAAATATCTAACNCCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGTAGAGGTAANGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATANGGTTCGTGCNAACAAACGCAACGAGNCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTT
+
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
@r3195
ATGCTTCAACGAGCATGTCTGGAATGGTNTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCNGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCCACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTG
+
,29*E#/"B;$#$*&#?E#E/G<C6-!/A0')8F.!5?2%?E%;0B26C:</,@%<:40/=.%+?+-$FF0;D"AE/??"%D$+>>C#;;%+BH=&$%52<8,!!H$5>=3D4=D*=74B,?$@GD:)'6:(B.!H/@3%6G+)#:%3)+D9!E03-'!G3#?!H<$8A.-/412$:A0<;15*E)?C:A3@/%9ACC<?G)11;11+):D@-;8)(E;3H(F>!D',!;F#@4%)DE8=*(G-G.*@D@245C%!5581++,="6F(5+99GH0/>+=D2??===,
@r3196
NGGCTGCAGGCAGAAATTCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGNGCAGAGNGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGNCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCNATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGNCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTAGTATCAGGTTCGGATTGCCGGGCGGGACGTCAGCACGTCCGGGATAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCA
+
!(+&!"!'((&*(*$(!*&!%!%+%$")#&!'%!!$++($'%)#&$!$#%%!&#!+"(&%%&&%()#&)&%#*)+!#'*&!$&&#%+)#*(&+*)$+!"+"*'*")""+*$$#($)%$'''&(+!!'++)+')&"%""+%'"%!%+'*%&""+"&*+"&+$%*#*)'+++#*")**"!$*%%%$''($''#(&&#%*%+&##%$'%#)$)$)")'))%''!#"(*$++$&)$$""&"&%(!*)!%*)!#!%!)&*#(%*%%#*&%%"+)#(&''%!*&'$+)$)!*$+(+$("#*!**((#*)$%#$""(*%)"***&#(()#"&$+$%*&'&"(%$&(!"+%%%+'%")+#+*%!!!%(!)%&"*%$+%(!)')*#!%!&%""*')#!$$'&$"+%"&+*&+%*%')%#'&+')(()$**%&$%)!(%&$(%#$!"!'+('!&+*&$"*)!%##("'#!)#$#$(()!%"$)*)#)*!"!''#&(#"(*"!"%$!$+#+"(&%(!(#*"+%!#*+#"'(!$%%+')!$%)+#)%+)*'!'##"++&&%*&**$!*##'(#')"&)"%%&)*"#&(&'%+"'(%&$%(+%'#%+"$$#$'")"&*&()$'$#!!$+#+)!')&(''+('%$%('*+'%&!#%""#)!%%"+)$)$%()#%%&#)#+'$+!$#&")+!&$)&#**''#+*"***$**$+*%*)$*$))*&$(&&+(#%+$")'!%)$))()"*"!#&))&"+'*&*(&))*#*+&&%*$%'+#$*)!&*+*#(&#
@r3197
TTTCATACNTAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATAT
+
)?.F(-?::)=C=A:'1>4-G:(B'&"F7:)9D,$8;-E5;8(52*3(9/8'D)/*DE1&=-8/EE0>(&>;G
@r3198
TGGAATTCTTCGTCTGTTTCTACTGGTATTGGCNCAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTNACTCAACAG
+
#%$F$%)1-(#">-!33!C*F;/-+24>@1$E"/=)-$#-G6A/:@$ABGB,5#A7(;B1@.6<<)5:&8F8=A=*5**!$F(+*?*3>,-2B8;66
@r3199
NGCNCNCGCGNCCGGCTGACCAGCGTGCCAGACACCGGCAGCA
+
%(*!&&%'(#"&+&%&!(!'$*(*+!)!*)"')"*"&*!()$%
@r3200
ATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATG
+
F,/5E?&$1C(38E!4/HF1H:6#%)G"4(/$AF;AD*+(A";>1%:<@!172('(3=$7=(*>%D6;G$<)017;$;2H?1A!6H944&!7HC;;CBA&+!670@&)25+&'C/G4!8H,=%">%-!)H;>7$):A"?B*#=D"4H#7>$!<2)/)=.>@F@&+$<C$-B"H5
@r3201
GGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCNTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCTGTGCCTAGCAAACTCGG
+
C:/.&=''!<:@<H)+%59>-B.<9$96G9!=9.$7%5$!,CF@E;%*413==,E9=82D4C9>1A#7*)!%:4$9&A>.GE0>.E4!B;2F"#(5&1;#9<<&.;&<!5.:HB-$3F3C5$A)=FH-"!=76!0<H$<$4B9:=9:!.+-8=B53=F)9"%0-51<0>FD8!;9..B2/)7)@(1$;!=09G2$&>0.CA0;"ACH%991"7=2:%<70C:9+5830G!#-72F0F4%3)1?H5C>:CB&&%5@+/9,3</9@G2+&<A@>986%,>+H*=?61-?&<10:C+A47H*6@)?3:5H7H84*3,7+BF55F!;7$,92G5/&@=?B387F/4H?G6)9@*#1'AE@D>-'B*=$191C/49ED'C,F4(,-B7@1>E'C#>E%=">D>=6F1!GF(%-.9=4.-(%A',,@39D$
@r3202
ATNGCAAANATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCANCCTATCAAAATGGAGAGT
+
=C!4785)3'$$="7-5>2<%.-4F&&77?./$-!028/@0GC?;$,(=88:70*7,!FA=*F7E:>(*=."B45HF7FC-H(D,;07!!E:E/D&?G+E&72!#
@r3203
AACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGACCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACNT
+
3-64')8<4048:AAG)*$H8#(!."2F:',G@)&,@E,.-',4'AGC!<'3CA.>9:+D,?87:78D$'"88@'=-;!8>!5#+'?>!.H%9.#9;-.)(F!C1@E%1,;<0>F2
@r3204
TCACGTAATTTACGGGTGATTCGTTCAAGTAAAGNTTCGGAAGNGCAGCCAGCAACANGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAANCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCANATATTCCNGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGT
+
7+379/"(>,E2EBB45"?75"$B<;&9=%)7!H5F'?.)CC71A>:F>'.;@D12'7<:E3*,(:+,=+<67AF;-=5F'7H-"H:&+%1*4D4)(;FE$E9AF.=G20A8=DD&'EDB(0C@'A#@F>:6&?!,72!FHB/5!C$)@>C.F/F>65'-)F@77;*1B*36H)"=&<:(G7.2-5071,E>.<8!C6E/+G#1=0+0<0%)$0;B(4::,B0;47*@D#48(2.7,5(+%7$9BH+A-'B!2$2$6G,8@>3:8B#$=
@r3205
NCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTNAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAAACATGATTGCAANCCTGATTGCTGCNTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTAGCCAAGATTNGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTG
+
!#+#!#*)+*!#&+()#!#"+!"+)(+#!!**&($'&(&*%"*+$((*##)'+%%&+!+)$&()#"+))''$+)'&)'*""()%%!'$#"(!&)"%(++%$)%(+!)&+()#%""(*%#(!"+!#)$!!'!*)")'%*+!()*#$'(%*+!"&!!&#*##+!#"%*#%!"*)#)))))!!'"!#*%%*)'$&(!*'$'*!#)'%%!+)!
@r3206
NNNAGCACAGTGATGACCGGNGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGCTCAGTGCGTACGCCATGGCCGGNGTGGCTCACANTCGGTGGTCCGGCAGTACAATGGATTANCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGACTAATCCGGCAGGGT
+
%'!+!!''%"+'*(')&#(+$"+#*"*")"#*#)'$*($+#(&('"%#&*#%#*!&&#"()*'!&!)%)""%%!(&!!(+%!$'+!)%$+$')"+*"#%#)+*&$&&+%$*(($$)$&$)!)!&&(!)'#%&(#'*""*&""$*)&**!)&#$&%)&++*+%&'&%"!!&*"%%'#$+%!$')+'!$))!+'("$)#%!#'*##**$(%)(*#'*$$"#&%#$*'*)#')'$)#)%+"'((")*('("'%$"+($!))$*%)%'**$&!!&*'"##%&#))")
@r3207
TTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCAACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCGCGCATTGCGGGGAGGAGGAGTATCTTAAATTTGGCGACAAAGAGACGCCGTCTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCNGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACC
+
2A7/E/D.E&5=+69H;FD>/&5!4,=2"77#C04C!",3?/6B&&72$F$&92@'@%A+"D!(1C'%90>;4("C5!%/49;4F7-0A@30B5,*),793!4F+.$)HE9#9A<&ACB((C2;+!2&<'7$D0?BF@=35;76-6:55'"4,(B21H=*9D,$<70,!;.E7>0+%>-;9(F*07#FB0G7-20<0,)8E%1=4,D=+0=4H7#4H4(;0E*,:8C2".,&>4<$:-F30?<252$713*)@?:$9?=9$#?:145,D<>$7'">,4!C237DH-)3D*-F"5@'28=8>*.@+5F">>A<.E2@,-(D/B3"
@r3208
TTNTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATANGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAANCGGAATGCATGGTTAAGCCTGAAGAAAAGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACTAGTGAATACACGGAGCAATGTCGCTCGTAACCAAACAGGAGCCGACTTGTTNTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAG
+
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
@r3209
GGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCNTGTTACGGTTGATTTCGAGTTGGGTCNACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTGATCCCTCGT
+
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
@r3210
GATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGANTGGCTTGGGTTTATTTCTGGNGCGTTTCGTTGGAAGGTATNTGCAGTTTTCGCAGATTATGTCGGTGATACTNCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGNTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTNGTCGGAAGCGGTTATCTTCTTTGCCTTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCATACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCG
+
';C!)ED%5('7A0C1<FG0&++@,=@*94'8E+:?7*520=9C!7"/'(HD(A-!.,6#1'++,9EF-&&)!?C1!($+=&>CH@E=$B3!3(E(A"789B6,-!/@(F;,+/'=.9#7"@+GC!+C>H=7E7'(D@=@8!$#@9C8A($>(C(;A>@3?-9>8%B64=+.5E1:.@%G&GH=5@5:0DGF!790$&A%,'D'@1D>1!>30#9($H80.9BB,7.+(6HA"8$C*=C4B7F@+AB@9,/C.B!=3!#E=D4(%51@?7C.'<G&6*9"A>/-'2/(*5$=5<)!95!';7&9=/>05(,'1196*#)=*24"A@D1E>>(?;7.C#4E4,3H:+/,.H+@#/A)<?"A67)255@2".#,15+G/*')0>G$H+'9'"7=;=3HE0A1'0/34;'F%GBE7:;$4,)8/3&):2>E<;F0447CF-*(-$1;:%%-3,6/%.
@r3211
TCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGNTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTACCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGNGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTGTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGTGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTNAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACA
+
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
@r3212
GAAACGATACTTGCCCTCTCTGNACAAAACATATAGATGANTAAACCCAATATTACATAACAATCCACGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTNTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAACCCTTGAAACAGTTCGTCGATGGGTTCGGGNATGCAGGATATTCCCACTTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAANAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCNCTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGANATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGNTGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACNCGGGC
+
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
@r3213
GCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCTCGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATANAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATANCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTC
+
26&4F"1<4G?;H4-D+HD.EEG?#?4AF%,3)">7*3,C+,10+G45E/3:"673=;!<+/@DFCA4BE!&>48%49F>;032";?;G;37%#,$&/H"/"A%<9@8@19!.;F)?$4#,=::>?E;'";$4E'*;'*D78*>=%:,4=:$61?>&,/:0/)=F9/)%F9DE3:=4A=C#F$5,!@2G9=6";-6!D'0=;&<(");89*-?%#E,(@1G5?.+:AF5&&"49):3/->1G$D875;,,87431H7
@r3214
NCTGACATCNCNCCNGNTNNCATAACCACGCATNTNCCGGNAAAGNTTCCANAANNCAATCCGNCTGGTTGCCTCNTTCGTGAAGACAAACTCGCCACGGTNAACAATCCCCGCTGGCTCATATTTGCCGCCGGT
+
"'))&'$$!%)#$)$(')*'(&&%#)#"$$")%$$#$)#%!"($*")#'$!(('&!+$%'"(+%!"!#"("+%$)$*"()+$+"!'$)(&&(+!))%)%&$&$)#$&'*'%$!#"%*#+&''&*(%"#')+)%"%
@r3215
TGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCA
+
G7EF#$>6!$:7%;#4E>@$EA8FCA;.4)C0!5B?GA+>)&6(164;784%5A/<"!?B!@2@;?F/F"55(FD0C!@#4":,C7=>#)0G-A2,?&('@))*4;?B#E/=6)3E*8".%4"*9,#1';?@$=EE&('D/;29G6$@(*1:"!%,%-0*>$E$<H4?E-4HF!6*3A<27AB2+2C442$C<@9C78<!5(292='-2=G"&D
@r3216
GNCAATATTATTTTTAACCCGTCACCTCAATTTTCCGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGAT
+
***++*"%+""#$))#+)%'*(*"%#+%!'!')+'"!(%*!#($)%+&&$)$+#(!#'!'&'$)&)$+(*(&*'%#%*(!!('$!#*+))%))*##+%#%$$'%&!&)'#(##+)*("&!&)"&)'+('"((!)'+%!$"('&+"++*!$$+!$"%##$+##))&!&))$*(!*+(!%)+$!&&"%!)(
@r3217
CAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGCTGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAANATGCCCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGA
+
B8:C<'1E*4>:C*>2A4224C41=<9B(FC5B-5("<<+.%DD>=04&FF@$'C'85FE=$HH<::07,=(/*2%&(*8">F+%8$(##9+=4=E')'!52'<70&@H3@;>/4")4&/<H,1D5(F!5B+6!:-&D$-90#0=@6/7%/9$<2%<%(-F+A=;*&*B9(0=%,4+@5!%A01'-G+;!B5;@9.3.,,/9+67-HCB-.E085()*9)"!GH;7D#+?)F"'71==4%B-1A=@9%CC%('F"7#0,7CE.%,?'3A:BA&8$.#+3):=...FC>("G>(1@0,.61!!>*0%EC$?@30(H>1+8D,6/(/(7756D
@r3218
GCCGCACTGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGNAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGATTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAANAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTNTGCGCGGGCATTGCCACGGG
+
((+"&"'*(+$$)$"+$)+%'+%)$&(($#"('*("+!*(##*#&!!('($"%#!&!"""#++%%+#%%"!%!#*++$)"%!!&&)$(+"&%$)"#!+%*+"#'"+#$(*"&&**!)++")'&"%"$$+(#*(+##)"$+((''(($#'()'*$+"'$)&"*'"+%)+'('#&*)"%(+*"%*%#)'&!"(()+*&$"%+&%)"!&$*(&((#"!+!+*&'*#&)+!((%'"""&")'$*'&!(%$*&+#!!"("#$'&%*'!%!$'&!+%+"#!'#%&**%%)$+%')'&(#!(''(&!$&#&+*$*)"+&)$$#'&(*%+*"+'#()!#!+$'"(*#*'!*%)"'"#&&'$$#!**%)*($&&&!(($&#')('*&"#("+"*'+"'*(#*%'"*(+'")!)%*%+*#%"!$))&((("+&!#*$#'#"*!*"("%*#)#
@r3219
AGCAATCCCCCAATTTGAGGGATGTTTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGNTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGACTCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCTGAATGGCAAGCAGCACTTTAAAC
+
7$2'0#/>'/,::)%5F05)4<1(D-<%9>G2.@+99FFG/.#C#F!;34CE9<)0C:83(=%6-0:%!B<-0,#8572#1.@;0&<-3$EHE&D59-8#.#=#,!1>F9%B&)8%>'B#G+8$3$3>:,6<.A&+>@."/7?$&/*%0((@+@+8B>4.96?,'&6'>=+62)H6*FB,<H1(&H=4+72(<2<H=<8-A?F'*.15@A0BD=,E7&!+H$D6!>,%@99H628>>HE9B(2F#)?19(=?>55324.+$C+&8/-C:
@r3220
NGTAGAGTNCACCAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACNCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAATATAATAATCGCCAAATAAACCAATACTCAGCT
+
)(#&%$&#!#$)"%*+*#+%&&!+*!!###)"$'#(+**$'!&*#*)"('*#!(&#*+&*$&&&!#(!+"!+'(+$('"#+"#($')))')#$('&"+)$"%$)$#(('#+'%(!$$$&("('!'"!!$%'#'%%%&'!&%%+'+'$$(#&&"''&*$#"'*&(&!$&%$!(*!')")%&$(!('&)$'!##(
@r3221
CATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATNAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGACATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTC
+
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
@r3222
ATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATNACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGNAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTNCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGANATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCG
+
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
@r3223
GTGACGGNTATNCTCCGCGAGCGCCTNCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGATGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCNTTTCTGTGGACGCCGCCGTATGAGTGGCGGCAGATAAAGTTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGG
+
*)&($'*''&*$#''"'*+$*+&#++*%(!"!%''#)&+"'("#)'!#!!%*&%%"'*+%""$$'#*"+")#*#)"&"+!))(#%$+$&'("**!!#+*%%&!""#(+)$!")')*+(&""++*%(%###*%)"&()*$#'+*&)&!*(!)*#&*)#(&#"'**"")"'"("#%+'))()($%*"(!((!+'#()&(&$*')+"&'++#++!'!"$(#%$'"($"+!!$)$&&!"**+#!+#&*+$
@r3224
NNTATATGAAAGAGACGACCACTGCCAGGGACGNAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGNACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGT
+
"#B)+>)*)482%!$&D1B$.G7(E2B>7">;'97GH#%;++7CE00CA",/DC'1"+,2;)C2@5.0)(;3D=E$7B'/=.<3522D,=:3*F:4#/424/:+709:!9E#$,+&,0-7D<(21H!1$3(0);"!.!-371GH$?7%!7>D$>)"B*5@C$/H1'+;"=9G0"F,B99@0"76?B'$**4<4&+',:-BD+>&#G(0%AG>@;%./1<"&911#'CF51(1E(2<EDD="/=6:
@r3225
GAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCC
+
9%ACD@0=?C01#CB"CFA#)669"&F?G519%FFA,D6!%6H$:D8&4(!"%9)$2,/94@(5!:.D;%87
@r3226
TAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCNATATCATTCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTNTTTGTNGCATTGCACCNCCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTCCCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAA
+
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
@r3227
GTGCAAAATTATTATCACGAATACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAACCCCAATATTACATAACAATCCTCGCACTCGCNGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGANTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGA
+
>D#$+?>:9*$@<#/'>)%.)0?%$C3&+&#H%7$)"%;()CB)A3+-?3#G?5*0@E!()A'AF&+5G2&;'8:FH)0?7.0!+8*E@6A9$H03EF++>-,$13B"F'1(856.@<B2/D6A&H4@?.<D.:%::<=<'CH??:41C:-(67E"F5(0&;C1G$/1308(+C=F657CH:0<H?0H0;%+>D/C<CE@C,"(,@H:%*30E)&665DH';"BH*+C""9/,45(=9&8G<%>((?G=,<<@;A5$<&+".<5'&2*5+9%*G;,-)F)@?.!,'*B24;<-/A=(/*;BE1A;')>
@r3228
GCCNTAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCAT
+
+"&+%&$$*+%*)$(*(%""!"&)!'&$!++%+$%$#*"&&($'(!"*)&"&"!$$++!$!!#
@r3229
CCGATGNNTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACNCCAACCATCGCA
+
#(#$%(&%+"&''+'$%')(*+((+"&"!"!&!'+'*&"*(")*)*&*+'#+"(&+%"&)($+#)!!&')('"$%#!%%&"!%'%++'$'*)'("+&'&++%)'$#*&+'(
@r3230
AACCAGCACACAGGGTNTTGCTTANTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCAC
+
G'%8@4!=G7,AH.84@":<83,**<BB5<#1?#65'<"1$@8,+CG!.,=1-;1F7!H69*<)E%$03"F".2&7?G<A6H2F,!5A+;GCDAH868A053#+/#-F5B>!6-7=$1++B@0-"<H(+4>"E"DD1E6E/-H&>70E=313)#>F-)BC/,)<G7-F"??'HD+;
@r3231
GTGGCTTCCCNTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACNGTCTTCCTGACGATCNCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCG
+
4/9HF#=47F-?+8>,CF3>3=#&.>D*)-:A*3);.7!9&.!<*4)1C8$9FD"7/2C!6G(6+%,,:/8G4@DHC#7@G2G,+)-B4A$9(>AEDE84'/>G@1<.3F3!*%-?)B:!"(%%-E5@$A<8(@3/>E7+C4E?F"E8""<,+B,$6F1=C,0@H,43DB"(DD+(G+'4:B?FF%C<>%402$G33=%A$4)A!8%C//-:,;F?37(7(E)&A+&4>,+:C3.53<:=-82G=1#AF<(B5-%49=?8*%1<";?&?/>0E'=H=196!54BFE*76%#C>07'";&?488?3;+?0%,*8D%G;F39&,B/DD.<B"GD2?(A:9+480,"#@C/)G?7GA%4A$E0-?66*5(<%.@E'<3&B%#;"9,3,+>G&9(-%3)C,<;F'>?72@&2%6*5'&4"'@4-F,?<."A;F(+)44?H/2D7DBD'G=D(C!H?-5&70
@r3232
GCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCA
+
<555;*D2#%B*$!))"107<C6FA0("H;,$93"F@1EE#>)@=,+-7D1)?D/6"%,;#E5+&06=9C,<?C>>:GE4'H33!D,-;G882+5H&0%6-"'DDA#6"@'8&+068)"%,7?F2E5:%-3D=G#-/,*E3@*:.CH*+G;?'
@r3233
NAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTANCCACAGATAATATTCACATCGTGTTAG
+
)%8%+D#E(A)72<8=,0@3#<A=%&-.E,0/9032#H*;%0FA&.1?,;=2'2D%8A=<1E15B5&C?(='H4'87EBH21EG&7#(=B)./A)4)8++*@'G?-$AFH9@%$*+*038=:>;$)E50*)A8?D$D693<%//2&@'+G+)4H"D*>6$:<<9<+?,)+;-/?//<.))*528#3?C.9*7!6(
@r3234
AGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTT
+
B-&H/-54@.&42H1.!4.>55+1,;'=;)4H002?A..;2>=0H
@r3235
TGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGGGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGNTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCNCAGCACCNCAGAGTGCACAGGCGTGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCA
+
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
@r3236
GGTAATAAAGCGATGAAACATACTGAAGTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTTGCCCCGC
+
$'1')-A3(4F'F(A+F:11HC%D0A.1"-$&8*.-%:A)8,B,+'*2HC<@=DH)/6D%;5<0!G)&3?78DF831:20@7C-#52.GD;#&#E)6
@r3237
ATGTTATGTTCTGAGGGGAGTGAAAATTCCCCNAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTANGCGCCGACCAGAACACCGTGCCGATCAGCCAAACGNCTCTTCAGGTCACTGACTAGCNATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCANGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCCGAATGCAGAATCACTGGCTTTTTTGGTAGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCTGGTGAGAACATNCCTGC
+
&-FA+H;BC/*90$3=GC=.F6#+?F34<('%%E/1EB.?<;4#.HG1GDG+8A43"-<5#:163A(2%G1";?%0D5#"/G>H-H!F1B!"*4+D=7:&"!?A5A,EH52A/>"!F>/9:1'4>;1,)<3B$58A65<*A2:(B-?D76'(F(/+&G-(-%85<>2AC62A>#0)6,7"):#'2:8A=@F6;>=($6&B*<@GA9D/=A,54#7@*=F/$1A@,$,B$*"84D,'FF:%710>A*><6#>+B4?G?6%3?.#C1(D@9E&,-G'+94H4&6CD>%B1H)51*<.!)+:$)?0GE8;7B(2"*/8)GH'E(:"?'$461&!@GC#"0.897@/95EF%(1A(7&@1945670G=1,.9H$F>&75>1#/C0)@@&B+=3>/3!2B";FAD=)/,(&+!A#EB:3?7(6=#&>G?@5:=F4>CC+6(#?54G$G.:/#.D!+'%)'746-5!619E9*C2/
@r3238
GGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATGAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGNGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCTCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTNTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTNTTGCTGGCCCCGTGGCGTTGCAAATGATCGAT
+
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
@r3239
GATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACAGTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATNTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAA
+
GG3>),?4%94'=92F5GC@$='"+6.!'$3</<*/H@#%:@B-F4$603C*03<+/$?@#3=!H<4-)3=FE!!47.@=:2C#B'@@=4H46D6B$EA5&:8EFA"7A-B1&@A5&6*3&14?->(&=%%/B8,;E(:-DE2596@(@DE+H&2?652D8;76=&5?%7);&%:?G(BG&;0)G)>%",<=-D:9"=F!@DCF.<2:"=&4:6,2/:")<88F:4,*$)H:?5><7#+4E"3!?E6-E(8'D?%DC<$E$6$-C058'%?-31H8/A:E'C0$-!3>?.;6DC:5&C'92?=24H:<7,<A5@G%6D!.)@H52,:,!=F51/6(.5/'%$4<<)*>"..@3A$4F;!6&'5<)>:A?$.;/E59
@r3240
CTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCNCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAG
+
1,D.E66.=445,E&5/*F9H7:7::-5DC:>7-F51F5=*&?.G)7C1)&86.="#@3D2458A;FGE%:>E(D:7=/3/,9985;6D<9'?@>8B?*?ECF1!DH@=D4G>6!&H=)$//G<A'!5B.+.,;49=,"CC&$@4,"(&&&?57@%5:3DE"BGB+.?;@
@r3241
TATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCA
+
G0/&(,H?#3.>"-'#9@G(169F>E*+/!,D9HD;)(3.3FF11%5=;&-B$;::BE0G
@r3242
ATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCATAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTNNTGAGTTCAGCCATTAACGCTTATTACATTCAGGATAGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAANAGANAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCA
+
5CFA20F#@;:*=;;/</GE#@;8A84)2"-FG6")C)!:&"@H6*<*6C2%//#7&<H"-#0/!E&1)081@:"&56+/>E/::>/0,)?B'<AC>7E>5*)"$@6/C7!/5D%C05'*68A**'$:;&$*9B/$+%1&6-*0@D/,EF62?+G@.7E#-B(B0>6F4#A890:<+",69C4,6*D*G76HC+3&))61.2F-B/3=A*=-8'#DC?C,:F<F08,DH&+0EBD4+!-?>94#2
@r3243
NATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAAC
+
!B$.D.G75;%CA$@$C(6=&'<$+;;#*,$.:C7FCF1!>!*%:8>!**6-<:A4$0/,#--E(D5@0-3'F!=+6<3C<D"!79&H-E,%$?00+)&!@<4=&-B!,15A?9@4'HA#$:?B%%:A8#$C:%+A+B<H;)5D=/D5=#?-7<!!F>F.CE3E>7*%$55@D10:<C2;&"+CEA*0?3B-";15HC!:FB)B<
@r3244
TCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGNAAGGTGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGG
+
1F1,)&80B26H0(A6:B'7'/025-@H?#=G;G+/4$C8=0>/9'7:7%./.*G&!=,A++*,6:F#@A.>5?<#*"H@7442(-"?64#H(+4>531<)$446=,(;50=01("FB,E&*G&F&"5=8<G)(+C%1/496H82*?<>8@*&F:8=<7-D%/9!86E?,?7G%1%2::5(4G<8D;7B7%),B+<G5)BAG"F:>="&H:>5E
@r3245
ACTGGTATTGGCACAAACCTGATTCCAATTTGAGCGAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGNCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCG
+
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
@r3246
GAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGC
+
&-#=*1H*20F0),53D+A/*$&#50+;-/602='B.0BC%2*F*2)1F7'2,>=$*;#HC3-6-B02@B7=&A-FAF/-FBE@#01?F8C+-6=8G:.?=:/4C$B7B%+A#@
@r3247
CNNNACNGNATNNGGNTATNANTTTCAGAGAAAAAATATTCATTNTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTCAATNACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCCGACAATTCTGGNAAACCATTTAACACACGTGCGAACTGTCCATGAATTTNTGAAAGAGTTACCNCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGA
+
#!#$&!$!!#'!!&!$&(($&+&)#)%$$&%("(&*+#+%"!'!!+()!"))%("%&#$!%%*)#(&%+%##)*)$!+*%"$'&#+(''#+"*$(()$))%")"(#&'(&")$)&#$!!#'!+"%+"(&!+%*'&)%!'%)')+'$*'%%'"+(+!+"'$$&"*&'!*&&$$))%"&)'+$!$(*(+(#'#+)($$+&#("&!)!"+*")*""#%#+!*+$%$'&%&!&!(")"!)+%$(&#$(*('+"'+$'!'%()&&'"&)+#!+%$%)"#&($*#+!)$"'%$)"()*#($+&*'(+'!&+++"'!*%!#%!*"')!%!*(+#%%*+(")$&&!&"!)
@r3248
ATCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCCCCCCTGAATGGGATACGGCTGATACTGNCGCCCCTGCCAGGTGACCGGCTCACCTTT
+
*"@8!23&1.A%@H,++/@".CD'.A21*#?$7"8=&(+(0?&(A(A)E2!E-:,?(<A><><!0+H3.==(#@:>$9E#D&!.B3?.!<:%9"6572,A$B8&";-2=+@3H1C:%6>1:5C-5C!,9=B452*7)&,&%('BGG>E/#=0HBC@*-6//>->1"$27:?G.E."3)/'**D)A(HB!2,
@r3249
TGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGACCGAATAGCTCGATGCACGAGGAAGAAGATNATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGNATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTNGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGNAAACTCGCCTTAAAGCCCCGCAGTTACTGGANTAAAAAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTANCATGTATCTAGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACANCTGCTGCGGCACCTCAACTCCGNTTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATNGCGTCGAACTGATTAGCCGCATCGGTNAGGAAGCAGTNGACGAAATCGAATCAAACCATAACCGCCATAGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGA
+
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
@r3250
NATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCA
+
$$G*@)=@A6;$C<"558#=3G&3,!$0"6+:G#'G27<GD+#F--3!'4E$!1
@r3251
ANGNGNAGATNNANCNCCAGATCGTGNTAAGANAGNGTNNANNNNAATNGNNNCNNNTNCGNNNNGNCCTNNGNGCANAGANCNGTNGGGACNNTANNCNNNTNTGCTCNNNCGNTNTNNANGNNNGNNNTNNNGGCANNANNNNNNTTGCNTTNANACNCN
+
#$""#!$###$"""$!!$"#$!"#$#!!$$!##!$#$$##"#!$$"$$!#!!"$!#$#!!!!#"##""$#"#$$#!$!"#$!$$#"""$""!#!!"$!#"$"#$!"#$!#""$!$$"""!!!"!!"#$!#$"#"#"$#!!$!!""$$#$$"!#"#$"!#"$$
@r3252
GCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTATGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATNATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGNCCATATCGATGTGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTNTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGCAACGAAGAAATGATGGGTGATGGTNTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCNAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTAATATTGTTAATATTTANTAATG
+
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
@r3253
GATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATACTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGCAGTNGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGNATTTGTTCAGAACGCTCNGTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCA
+
<D,H8@=8E!;6*;H11&E0'8<1FE8?9+9GF(,%:?<1.6'"534"4?(/,(BD*$G$C(,!3@D9A;H.8D<:/*7*6D"H!CD$@&3,1&8B1F,A%,<GF063:E.?8(G2H&C8%DF:%C451,$6:8&8/<6#<F52;3C;4:@B22:$GAH0$:5&)(*:B,H#+!:H:#=;7;)(6)+56>@(?!0GEA<-!7>"9B122:33>>&9.G#B<=?GG7:F,**>;:7#C2)A&.:0$DCF*BG6$D&8=@2;&EF-*EF-?24
@r3254
TCCGCCTTCCACAAATCCCGGCGCTGCTGTCTGAATTNCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGNGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTAAATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCNTCTGCG
+
'061E@D@4)<G65;5("7!5$D@%/>.:=.9*$%9$"15/5!D?8F+3'47*F/-A5?*'5C1$G.:6.2!'@-'1G-4&54855"5-:>+E1/84<A5@B,DA;AD@%E8D#B;:010ECF7(?H1#E2&=HFG2G@(5?0.4-061#E8H0'D;H&:%$EBD..FD;G/9#B-F?!4(06,,1+0D1@C@*'"DD)'/B(><@AE1F+=:F'<):B(6#E.5A3.(7$/FD69%0*,6/BCG5$:0G!31E&'96-8)H5=$>:#,E";6%'0H=176:1*)E5D:%F;'>=8H+7;=HG<5)@$:5AE)>!A
@r3255
CTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTGTTACC
+
,-0'%A3>(?*343.0G@%)<&6E)B/CC##20;8B.2-;!*!*6',C=%$-<%G#A;;""2=613+98'1@A!7$'$.6-@
@r3256
AAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTG
+
9E&D$4?C1"(&D9?'/D=:>.7@BE<E;71ACC%B%%2..?('5&;/'-*BC?7/=09'E(/G<'7A7;/=/?C4-$5A0!6/G9;')D8)4/3;):<0$F7/%&<H=:8+'9388C0./?,C*FA5;<<</>H7E?48&521?=&.4C20'.0FC(5)<@F'GC1%=2!*!0EG8H1)EA+$28/%E.1=8.:,HD*!7-3"/=:F5D*8,F;<@4/,6'!=7)22*'9)6'3;
@r3257
CGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTACAACCCCGTAATAGCGATGCGTAATGA
+
H2*).)B*G6$67#CE4A0%+:('"@:*&:$A04=44&;"C+,);"!)@(=+E>8/?$0'%A8'(-#08;7.E92&;:*&6F?9"?+7>A;,A!B=:>>A1>2C'BH-9)6?)A!,67#==+G0;4#H++<H$$0+!G?/8<$C')508'>#)A,*C*C"/4.>9;+:+)DD%6+;,6.=3=<A&+0F9(3@57)A<H)/9;'+608F>G
@r3258
AANGCTTTCATCACTACTTAGTTTTTTNATAGCTTTAAGCCAGAGTTNTCTNTTTCTATCTACTCTCNTACAACCAATAAATGCTGAAATGAATTCTAANCGGAGATCG
+
%"!#"&+*'"!!#+#"!*&*!'%))%*+(%$#"!*((&))+*(**)&*$!&'*("(***+$!!&%('%+*+""%(+%#&(+%##$)$*#"*)#")#'"(*($!"!'""'
@r3259
CCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCANCTCTGGCTTTGACGGGGCGTACCGCCTGCCGTTAANCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGA
+
+)!2!>7FF3AE$=:/E/%C#'<DD)*4)6@87C'&,G),C<F9<;@..0+D34C;%(2,G5.F)'CH9;"76)(';#3953'/7EF04/C1A9!>:%B+1=6'.$H610.$$H#>.1%.$*+?0&76:H5-E?969;243
@r3260
TGCAGCAAATGNCTGAGCGGTTGTAAGTTCCGCAATAACGTAGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGA
+
5A6!/;*+53*-7:"94$E*9D>(*:$>&F$223@;>53C!,,<&,?@(B4:$EB/>)H7B+/6!32)G4H<$37:!:=H>(B'30.=&AH.9%E"
@r3261
TGGCAACCCCTACAGCCATCTTCCGGATGACGTGCGGGAGAAACTGCAGTCNCGGATGGACGCAACCCGCCANATGTTTGCGCAGNAGGTGTCGGCATATACCGGCCTGTCCGTGNAGGTTGTGCTGGATACCGAGGCCGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAANAGCACCGATGCGATCACCGTCATGCGTGATNNACTGGANGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCANCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGTAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAATGCACAGGCGCGGAGTGACACTGNGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGANGCCGTTAACGNTNTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCACGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCCGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCNGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGNCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTAACCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTANGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTT
+
)*+%$)$*(**&!+!!((#"'*)(("&"'+*")'#++**!)*'!)$)*)*&%!(($*!$!'!)*""))"+('*#!)#%'"'*!(+%)'"*%+"%*##'$(%+*%"&&)%)+'+$!+("#+#$!)*%((%%&%*#++**!*%+'#'(++(**!*%!"(!+#&+##"&*(&)%!*))#(+)%)&*#!)%++%)%)!*%&&!"'**+('$!&)#!"$)%%#+&!&"!!'''"$%"'*%+$#+&*(*"#()!+%$+$!&'&*#"))%&&!#%#'''"#'#&"*%')*$+"*)''!+*#&'*&&&)#$!*"+#&&%#&#+%*(((!%&!()"$#++*"%!%&*"'*)+!#*"*%&%%%$#("#'+)"#%(#(!)&&!!)(**)'$()*(%##+%+'"!$#$%)%!#)$'#%)+"(*'*)*&%"*'$+!"&*&+("'#'&"*%'&&("($'&)$&%#%(&'"%!"$&$**+*#*&'"*%('))%$""))'$%"#%$!"!*&!'''#*"+#&'+(#!+$#!""**)%%!'+#+%)("+)&%*&!&("!(+)''%!$%)("%($)'(+*+!+#*'#$+)&#+*("#%!($&!(&#&($)(+''"$&%*'!$)*'*'$*)"""!""$"''+(#+)%++*!#'*!$(*#%#*%&"+"$"&"($%'+)()*&)'!!(*'*&(!!$!++(&$*)*+%$")%*()$#((%++"++#(+!*!('+()(*"#$!*+$'!#)'%%&)"&#"%+)!+(&++"('%")%%'%#!#$"!))""$)%+&+(!&)*))"***+''+$%)#*)*"%)%&"+!"#)*"*)&%(&)%!##%%'#)%*)$#'&()&'&!*'")(+$*#$"+%+$$!))&'$'(%&!*')&"*%'+'%'(*#((%!%#"''$(&#$)()+!"'%$!$)"$*%#%(&(+%&("(&"*'*&"#(#*!)(*'$&$"($!+"$)'#$*)!'*$)&#+'%*)'!(&!!&&+%+&&)#"'+#)"+$#%!*#!)$*$*#'*+*#&)"+'"#%&+'+$)$%"++!%(($#*('%)!*#%&&&(+!!(*)&$+'#')$$!*)'$$+(+&#'$$))&'#)+('*#$!%&&'"*()##%!)((*#+**##&)!%(!#*+'+$+)')*(%!%#$!)'"%!"&&!%&!*%
@r3262
GTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTT
+
3C8.#91"F62#G:G<)0<?8;#&"0<5-;=3<+,E!$).$%(,"6'?C.'#+'HCD08?,CH!"G/@FC"3!2+13D-=&3H:C7<2?BA"E!*'/=;+44320GC$'*/<6+4>?)+94#E,BGE/%EDD28=>)9B$1$91BCFB7:#5;/BD4H76%*B05.8@F%3!B+6G*.,<),!)'26=!<9"946(/;95H64EE
@r3263
CGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGCAATATACCGCCCGTCAGGAAGAACTGAACAAGNCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTTCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGGGCAAATGAGAAAATCAGACAGCAGCGCCGGGATTTGTGGAAGGCGGAGAG
+
F-D8@>CD+1#(8$,G*!:,A&#6,A&=)&/=(&?0$##HC,H13"'%EE$>66?>7$.%E::;/H1?("%$H&D>1C415+*GC3DFC$$(4>F(>)@CA124+#FB(%'-1G'(F73$5/-+=2@1A5:3>#B322CD<''<'96$1-=%:F7E<:5+,*<B>+E+2)3C@,$CHD3;*$C)G?(1>BG77!83#-C97"&3<?E==G6BF04HG1;5"!?'EBA"-G'?!05@AE&'EGEB"+.-6$-@'A)H&23!79C*8;!0.4(;>8@.9G7*#:)!3%9G#FH</7=H@/4)#80G8G9.C410-$/.H>6H/#@A6&@
@r3264
GATTTCCGTCGGGCAGTATAAAGCCGCCGTGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGNCCGTGGCTGATCCTGCTGCAACAGGGNGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGGGGCGACCGGTGGGCTGGCGTATGCCTGGTATCAGGNCAACTCAACCCTGTCCGATTTCAACAAAACGCTNGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCANGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGNGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGANCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAANCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAANGCAGAGGCTGNGTATAAGAAAGCAGACGACATCTGGNATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCNTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAAAAGGACNAANATGCGCAGCAGCAGAGNGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGTACGGCTGCAGACGCCGCTGGAGAAATATACCGNCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATGATGAAGCGACGCTGAAAAAGCCGAAACAGTCCNGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAA
+
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
@r3265
ANNNTNGNNTNATTCNTNNNCTTGNNANTNCNGGNNTNGCGNNANGNACTNTACANNACAGGANNGGNACNNACNNANTNGANNAAGNATAANCNTNGGNTNANGTGNANTANGNGANCCNNNNCTNNTNAAATNNGGACNNNGGNNNNAGNGNNNATANGNGNCNCNGTNCGTNATNNTNGCGNNANANCNCGCCTNNANT
+
#"!!"$$#!!$##"!"!!#!#"$$!!###!!!$"$"!#!$#!"!"$$$"##!####$!#"$#"!"!""$##!#$#"$$#!$!!"$$!!##"$""!$#$"$!!#!"$$##!""!"$$!"""!#"$"##!!#""#$!$#!"$$"#"""!!"$#!!#!!$##!!!$$#""###!"$#""$""!!$$##"$"$$"""$!"""!""!
@r3266
CCGACGGCGGATCGCCCTCCCCACGCATTTACCGACCGGACTGNCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTGGTCCGGGCCGAGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAAGTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCNNTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCNCGTTATCCACGATGGCCTCNTTTTCCGGCACATGNTTCACGNCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGNCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAANACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACNGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGA
+
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
@r3267
TTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCNGATAACAATAGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTNAGAACATAACATAGTAAATGGATTGAATTATNAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGANAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAA
+
%0-%)+A4-=+"A+9#A&8,?1,F,E6D1H35!D@#+$<'$38D/.BA('<AB'DA#.-;#@3+HB8"-4%H##AB;EH.4?*44)%(@.B2FD+2(%E*':<+D("*FDA$3:/G&4?DCA!!9;6?-3-/E,F)-,C=0%03%D*(.91B%'%/-?4&E3>/-(DB'"11-"??2'"21+GB",G*2,,4E9+D349.#F:374>>/8D3>9'<?F>+/-
@r3268
GCTCAAGACCTTTTATGGCCATACANCCCCCTTTCAGCGGCGACGGTTAAAGGCAGGCGGTACGCCNCGTCCAAGCCAGAGATGNCAACTTCNGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCA
+
=D.!$086&929638*)59@='=-)1::'7BE"#9:H7B7AG?1!%!F2AB+@4).-4A22,40<8@).6(E1(7;D&+2.D??27G>@-%;9B799C54C16HE8;56#$>-?4$6@6*=29BADG:=6C2=4-?6&90>F#G:A>F52:77"DG"/D+?375/F$#:/8<>C1BD2#D).5)#&3;D1:;(@9E:GC1A1FE48'/45C.&!4/7C6B7%F%9)?E.:&@?/@
@r3269
NAGGGTGTAANTGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCNTTGATAATTCATTACNATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCNCGTCAGGGCNGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATNAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAANGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTNGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAANAGAAACCCAGCAAACATTCGTAAATGGAATGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCNTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGT
+
'%)+&+$$*!&$&%"'*!)*$%+(#(&+($!+(#!%!$'+!+'#!"#$)("%(&")*+$(%%*#+*+)+)'!+$)%&")%"%)$*(+"%"!!"#'"))+"&++'(%&'$))%$(&!)!"%!*'**%*!)((+$)'&)*"()(#+***)*!&))!()##))'$#*!(")*'+")$'+&)+"#)(%*%!('"+!*"#'"+*&#%(&()&&+#%)%#&$%$!#$%()*"""#&+)'+$%+()%""+&+()!&+()%!+%#!*'&*(!&"&&+&&"%*("&$&#&%*&*()"&%&&**#%&"$"+%%$!#$*+%))!*&++&'!+#+$**#!$)%)(*&#*()(%%(!"#!"))+*'%#"+&(&#++')("*!$#&+!&!()%'+(%$)%((!#')'*$#("))!*'#()##(!!)*"!+&'()+&"$**#)+("'+#&+!!*#*##"$&($(!*)+*&'&#&!')+(&)%%(#*'($('$*!(+!('*+&($($"!("&'(&++"$+'*+&!#$%""'"*"""(**#'&'!%%)$*$'%(&(*$#)"!'*#("'#'%+&$"(*%*'$!&"$"&)(&$%'!&!*+#*&#(%)%("$#$%$%!""!%+!)'(*'+'&')*&$"##(&(*$!&%#($#!#&'#*$&$&$'&)*)+""#"*($#(#)%$)#)#+##'"#)$!!+#%!!*"%#&+%%#(#%+$($)"*&$'*%'***%$"+#+&#)&*)*"#%&##+'*$$#%#*()%*$$"#*#)$#+&$"**(#$&'*+%%(+%*%(*"($%%)+&"*$$)*'*!''%'##($%(%$'+"+)%+)$($(&$#"'&")#(*#)#*&$(+&"(!%)++"!!$%%%!!(%!'%+!*"#)'+)'%$*%%'&!'"#'##!(!+!+!*!&!&+!"#&)+)*$#)'*+$*+)')'%*((*!#%&+((*(!'$(!%!+#!
@r3270
GTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCGCTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGT
+
B,>D85?2FC0=875*$>@:7:(791.D4B%>%-.H>.A!?G@-?93@9,4CFG#!0#.2/*BC+&+((')&@)+,F>!BC'2.;5F/5==#)C%H+4D58D=3<H?6#,(?$/G%>,"50H"87-9C93?@40?D$0#180,,%G:'!64%/;/:4?=5(7B!086?G2>35>*$-"72'!4,?3G+%#CH5!2AD*%C96&1++<?8@9C;:B2!::+2,
@r3271
TNTNGNCTNANGAAGTACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTNCGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGA
+
&#*&(%&)*"#(''!+)+")$#(#&$"$#+%*+(%)(&()&!!!$#*&!"!'**&"%%!*%"'")#(+&!)"""$++!#+$**#$**+*$*#'#&'&()('!%%
@r3272
ANCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCNCGACGAGTAGATGCAATTATGGTTTCTCCGCCNAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTATTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCNGTANCAACAGCCAGTTTCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGAATTCGTCAGCCGTAAGTCTTGATCTCNTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTNATTAACTTG
+
,735>"15"+11.H(4.<%*$;#CE*85$+>7985;;#(<$A&9"$<?%!<B'E4%*,(,=+8E=F+88BFD-/;+0"E+/#**D$=F'><=9A$-E3&A83>$";;#',<?;C!,0!<$3GE$55B1<D75#1678-;H.3G8/4,*E,D'0&*-$,AH:H@)25G8<,C.0)3?'D-(38=&BFH*%(9=GC(78/:0.E3>;B&97#!;4>HC$-A6#5.H>42-G/=E89*B,-D"%?!?*,/#?.3!70"<4(30/F98A93>&!@.2,-<,!!-6B/<F*!1;7".,20,G,1/)D;B,%/==H'6%2<.<.<%7)-9%1!A0+!8,4,@-1;640D4A%%3)A/%AGE3@./G//H&D&?/<4D(2$E:5-)H+A-/4AB8(@+&2(2*-+<=9'5)3?+%';54>-G(G6,-+$A#4>;+/9+$;AE+,!4*=E"=/B50&DF9<41:/31CEA5
@r3273
GCCGAGGCTGGAGTGTACAGCGGTCAGGAGGCCNTTGATGCCGGACTGGCTGANGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCA
+
)D60+6!)>.6;:$$"2!FD933+E;B<<@2@437&D'&:-D,66E%:0H/&;;H$*5-$B7!?E8-18'B#)-0?-C,#@&*7;:B0C"'CD$A)H:AE7:/<!"0F-!$/+0')%+H29,D::);;!(?2!C(*7:H'11
@r3274
GACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTNACTGATCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGNCCGCGCTCTGTCATTTCCGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTNATTTTCATGTCCGGTNAGCACATTTT
+
F##?%,F'%<15HF5G54A-!1C=%1)=G!!(*D'!!=B(H2BCA:?9"/D3+''6##$!2)")F<1+5(=@H3<(D4*@2///:7A,A.4/3,*5&:D694/<>=ABE/?!.#A,%@!)@#)5#E:'45,*4B.;$A@6;H0=#B,E><G4(B0C%F*7/HA@06.<H9$+,:/307F5C=81)G6-F)?!#0%%/+4?)A2>&&%?7&+15-6:@/#GA2?,B*2A,>F*&'5E*G6B+F+0"57#-<-'*$;%";6$2'0A<@2).4;:G*/GB?)9$2B1%;<4>)!-1D"D&D"?4-1F-9)=;%'<5'4=><D(B:48?D,9'C?12F:?=-)=836<"?49=;(>8,D<D2H/8@%7.*7DH:H:A4"E%A.B9?0B-&@#08-"<E%"+6(53!5-)+!>7&A97?(,B>F1&H03EH&7*..&A0(A1@*'(
@r3275
GCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATNGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGAGGTTGAGCGAAANCGCACGTTTACCATGATGATTNGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACNGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACNGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATNACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTG
+
F?5!:C/D(:&0<"3:FF)B'-8$)?0,E%98>C@E@F%)=G:62*?-)'+$44AGG62/A)"7BCA/",CD+@&BE-=/-5+.0#"A-D1F&;5G-B./@3!E1;9!HGB!$+A279%F<B0F3,==BE"?:EH9F?-1$H.A67C)*?2<223)%;:1C1GC.C:@!F*<$$(49/E=:6H$1!57#5595B1&/!1=$:6<*/9;-5C:&:6(@B=8/:B#6(">27!-#%'"71"H<,1@>-2+0%E15+1>&B5#-%($,6**5.*H.E,"$+C7B.EF>>9?2B:FF;H(@8G1&%F-9<%"C':C0#',:B>%/E?)6=?.)=G')"AD1H?0C)/AA"C6?/-+B;@;'5#B'H.;)5</=DA>"*/@>?(<(.E8,:2.-%%/(=(4#@1088(.9H9@C,G%0/7;B6$1>D&!'57?@(;+&=@2'@<
@r3276
CGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAAAGNCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGNCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTNACAAAGCGAGGCTGGGTATATCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGANGGGCAGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGACTCAGGTTTGTGCCAATACCAGTAGAAANAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGGAGCAGATGAGAGAAACCA
+
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
@r3277
NCGGCGGGATGGTGGCGGGGTCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACNGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACANGCTCCATCCGCGTCATGATGGCCCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTNACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCNCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTNCNGTGTACATCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTNACAGCACCGATGCGATCACCGGCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGG
+
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
@r3278
TCGCCACCGCCAGCGAGATGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTG
+
9:@,D;*63;5@?$)29"9:'B'C=1D&C#:C@::'>B,++=3(H'19-.8!'0?4C07"%$7EG(3%%"2G>.-=8+@.+@90!D2!(=4.@:BB-;7>%.C&-F.%6G!9,@,7B6ED</0$$*1$@'0A8G%61<%GA7:FD=$#5(!#>%@"?3%D8:776(E5,DE(?20;H&GA4==$CE-7A-"-!@=;H&$>;*3,@8?C51(49*.6#(>3BF$H0&'1/H>=$7D!F7=$&:"?
@r3279
TTTCCACCAGTGCCNGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAGTCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGNTATTTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTATTTAAGCCATCCNCCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGNTTTCACATAAAACATTTTGCATTAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAAC
+
D$)458,F15%+4!E1&=C&?@,4;:?>!#5:D@,?)27,4.4(@>?+?-5)2E4+0<.+9H$&"@,A2?D=-+H;<#*9$0%1F54D?8=*+'$@>02F=A(%;EEF=4:98'/3(6D-&775@;*4D<35G%1*,<:=7%6HH<:;B3=A%82=)38GD;8G-).)@H#4=*0"F-59-G'65-B5%301+1>E>$7:B**=@6G58!.3>@-B(<43#(H6H2<#4G<E>@/7!@=2$68H,F?C.!+B-7F6@&7*&>!>65G%1/CE+>.,%")H74:*7,'1G<5(D9BF*09&*'57):,+CH*212=#&1&'G?-7'8?;:82>F-.$E1'AA>:=<#;B$1)4"=1;6%782=6&816<?37806*,*8D(=/'+'<E+G2;<=5&1<+#-,(":7$(!7,4G%E:4('H+-0:$A;/936/B<BH?1,=GB<6C$)@$-3"5-8#+;#'96;-&4.1,9F+?@86*H1$"=92/:*62-.;*%;6#
@r3280
TANTAACGANCGACATTGCTCCGTGTATTCACTCGTTGGAATGNACACAGTGCAGTGTTTATT
+
()!'$(+!%+$*%))'#"!%!$!+*&*)*"'#"!%!&+(((')*$)!++&*)#")+*%#'##"
@r3281
GGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGCGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGNAACAAGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCNAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCNGAGAGCCTTCCTGTTCAAAATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACCCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACAACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCNCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTC
+
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
@r3282
ACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAA
+
,$8)8A9@5+@92-A0!*GF)5FB<#DE"!,E;/%4<%%;+%.'5E0&&:2..;&G3H/87>0#>579=G"-H7##3'>354-D688<D13C&-A/&?
@r3283
GGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACANCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTGCGGTTTAAGG
+
G<<B(.A.343#'#<$@-7),@C5&9H8?2/:?7!"9G),72,9<C$-;0@?D8'$7F@G:=.&,>*''6:D?F9<E0.E.2/7?BA%*D<C$:+F,&&28B'(;<:!+,F9+)*::A11>FDA;B9
@r3284
CTGTACTGTTGNCACCCGTTTACCTGTCATCAGGTCATGCAGNGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCNTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGNGATCCAGCTNCCAGCGGGAAATAGTGATGCGCAGCGCCG
+
5+8=>60F?,H($E8BA38D,1'C9A=?F.'>3+0:(9F-*3:17?5?%*A:,A06>=1HC+@:*G0==-14%&AC28%&&!)H>':'G(#$(;0!?:0"C-17E4,+(A$<*,6?4?-6"53H;-+5C2)C'*BB@#3%!);+8D=H4AD8FA(:'H<:%(4%HF,H5B.*8)#H7$=*5E*BF@A0F*,1A;7/(A4"7+>0E@:>+,6E@<E<;
@r3285
ATTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGNTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATAGGATGATTACGGGCATTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATNCCATCA
+
!*+*+""&%%!&'$'(!#"#$!')$*+&*$#)'(")*'$(&#%#&(+"'+!$)(")&'+&'"%*)!&'#"#)&*)%$)'*'*&#'##%&$""*)&!$&")#'%($*"&"+%!("&!!!+)%)%#&$#$($*"!+(&&&)!'"*+&&+)+#((&&(+((()&$'%#)&%'((%('"#*'&"!*#*%(("
@r3286
ACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTNCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAAC
+
>D@H!@FB5%E<(06($=GC,%%A$(!5)!%%!-204DHG:)8FDCD>7>:1&',3F054$&:4:14!<*G(;67:=7&BA?A/D?6/!H4F8=;@*=;,%-%@G491,?$H9/HC)C=8-$+4=>%+AH?!@87?G-3C098*7>'++1E>6A<E"8+*,2:2C2H%>>$&=,.=!7@!:A5&-9$;0-7#EC--!5E
@r3287
NGTCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCNTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCNATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACNGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAGAAGAAANCCCNCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCANGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCNCAGGCGGGCGGT
+
&%%+()))+$$(!)(+$'%#)#%*$!+"$'%!)#'!*($&!%&)$'#'+'#++"+*)*("+"$$*%(#)%#"+#!()++%!$$'**'$(*+)))&!!#!'&$)'($"!(+&!!+(+&%)%(*+"#(&!&)+$*)+$$*"&%%#&!*""(''$')%$()#%!('"%*%(*+$)%!")%&")(**++#!!&)(()%!')!!((+"*#($%#'&$*&')$!##"($#&&)&$(&(%'+*)*!+(!)+&$"'#+#!$&))%*%%+'+)('#&%#)"!%(&+&%%")$"$+%$&(+'%#())$($*')%!)&%"*"!$(*#)*'&*+(+$"$+(%!$$$)'"')+$!(**"+)))'*"(!)"+"+)'#!"'())&''))'''$)**$'$#'*!$("!$&!+*%($%$'***&(%#*)(#%%&*)%$*!##"$*)"'!($&!("&+#+%#&#)"##$&+&)!"()&#*(%""&$%("$!!#(&'++&&(((()*!))"&""%&!%'#!%!))!')'*'!'&%')$&"&&%!!*"+%$%%)($(()#$%%(%$$!'(%(#!'$*+&#%+#"()#*#'(%#&#($#&"*%%#*!*+!#"'*+!%(!#+*($*")&%'!'+)+')("&'$$##"$()')&+&#$&'"$'&##
@r3288
AGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTCGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATNCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAA
+
3D,,<('0+3-!@F&0,F4@DFB#).1-4.$5";8(95!!9)AA49CA,F62)G9;C((HE0*'F1;//2!D@8$B14)A8G3@,)2-,H54)=G-9/#6?:6H/<#37(&H74,)H%H<)F;A!,"C#=E;16F>E5-&C"'.",EH$DD<!#0%)2%#(5"@-(GA7#.H@1%D<B0+05'B#4C,*G#>A)$D"/C1E#B37B;@G=BB4('3):?93%-/%@=#??:)A<-
@r3289
GCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGC
+
H42"01&*A&,,B-,#C@0<@9:B*AB?@"$8)?;=(9)&B$#'C
@r3290
GCTAGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTG
+
7@GG%>.F1&39DG%&*+=+C0;(3-C*0'-!(F4:F7<D&EC2&)'*?#*G
@r3291
GGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTNTG
+
35510!A@@H@?#-9#AD&1>=<'3?6#$@B&D"*424*92*:!'"#.0$3%D>*,1&*+"$EH#85:D"4!>C(C*!:=<*1%;$8C>+>28F>0
@r3292
CTGTAACGGTCANACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCACGCTGTCTGCAGTGACTTCTGCGNTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGCTCGCCGTCAACGTGCGCCCCGTTATTCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGA
+
D"G9(DH('#-(799?*,9H,<,*<+.-=$=>59F!)!/46:/..?F,E':HBH:5%7/6<-22:2:2*@+:20#-6F8($>2/#$876E7C,4+027'/'9/#%3<CF=-83?8-AB)-.BC#<&/)+2'$%$0E?&=4:/69#(.=9$&%='!/(E)-7#$:/(C/0B<4?C5C(#(2;1!B9!GG$?H$43<;+3?6'1C'"7.1-,BG'H&:!54G*B5G=,%>:DD-:#):**C#39+885G#8#*'
@r3293
CNTNNNAACAATGCNCCTCAACANANANCAGATGACTGNCATTTTCGGTGCGAGTATCCGTAACATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGNAATTGAGAACGAAAAGCTGCGCCGGGAGGATGAAGNANTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTA
+
(%)#"(*"**')(!%")%#('%&&($'$&(#)((%"*##+$%"+!'$)$*()&(&#(#'*$"*"+")(+(&&')((%!)$#'"*)+((%)+'&$#$"(+(*!&!&($++%*)')!&&$!#'!"(##$)*++$(%$!$!)"*$"#!!%$)(&+$&)&$#*!'!+#'#(++)*$&*()&$**+#!(!$+&&##!+('(&#)*'&(+++((+"'(*****$!%!(*$&#%")%&#%"$+$%)!!$'!'+&!&)$!&#)%#()%+
@r3294
CAACCTTTTTAAGTCCTTTTATNAACACGGTGTTNTCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTNTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTNGTAAAACCTTCCATGTGNTACGAGGGCGCGTAGTTTGCANTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTATGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCNCTTAATAGTATTGNTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATATGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCANAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGC
+
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
@r3295
NANGGCNCAANGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGNTGAGACGCTGGAGTACAAACGCCAGCTGGCGGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAANCCGGGGGCTGACTAACCGGCAGGCAGA
+
'##*%$!("$&+&&!%+)+*'#$*$%!)**$(*&**#'+'!'%**))"(''%"*%!!)+"$&%%'!(#+#+%&')!$!'*%($*$'!$&)*&**%&'+$((%"&#+++$(!(#!*!'$"&&'#)**("*"'*&)+('$%'#!#%(!(&&'((&(&+&#'"+""#)!&%#')*&%#(&(+)$*'%$(*)'!&#$#''%))%!&#$'&"(&(!+"$($+(&++&(*+
@r3296
TTTGTTAAGCAACGCACTCTCGTTTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAA
+
<#9)!F#G'7"(6@;#G3@E@'"699&7.'.>"C4H('%G;";-!:$<+@C:'$2@E5,((B-?A5
@r3297
GACTGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCANGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTATCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCNGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAG
+
9!64<(!-*5@5&-<)2:?4H></C?%@%'!!#::<D=&.)5'$AD*8@1'#,748+<AC"..;H&64*=>F4+#8FE,,A,#'B3F)1:.%6='54?;4$$@5//:>+H;#5,$BH9*>94?2("H0.!"@AF:EE6."39).)AHG7>/=F5H6/9D,6=,23C!#+?HC+/8,?(@7#$@0!2)1;H.;,.+)*$,<D<%4;3&)>6,*A)!76*46B21B@5+2'575597:(!C,=/B3?$C%&4+3@#:.7?E()4#/F81$.097&2D=FD,D>.)#-3<88<F)"/G<1(.A"(-5*15::.-)=(:%:4H7@$+9##C-%0E%+<(<F9DF/:,6'E5<@&(16>&'#':-H%>13>1F2@850C(%!@$CH;554F<%(%@&?>+D7D3?BCD!&"346DC%5FF+)B,C.G0#/88C6,!-<:%@
@r3298
GCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCNTGCCTGTTCT
+
(+&-EC>62FGD)B%.C,G&%6H@+D=E34<("=H)D68G60%>:<4)-80
@r3299
ATCANGNATCTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCC
+
!((*!%!))($'+)%)!$$""))+$$!("(%#*$#((!*%'$!((%&(%"$!(#*%!!"$'&
@r3300
TAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGAC
+
"-.1/0-F0'8#=E/+%<$H*5!D)!6B2@D3C:82"7;1C?D/6620!B3E=<2<4F=G+"(>;05#GE>8B)GG!A:2C@HH)1<.!=H0<'(#+!@=;8<7C'@D&.AE
@r3301
TGNGNNNNNCNNGCNNNNCANCTNCGTACGCTTNANCGNNNANNNNNGGANTNGATNGTTGTTANNNCNGATTGNTNTTTNNCNGNANNANNGNCNCTGGNCNTTNTNNGNCNNNNNCNNNANAGCNTNTNNCCC
+
$$"#!!##!"#$"$!!#"$$"!##$$$"#$$$#"##!"!##$$$"!$####"!$!#!!$$!#!$"!!""$"#"""#$!!#"!"##"$#!$#!#""!$!###$#$#$"!"""$$$"!#!$$!!"#$##$!##"$"$
@r3302
CCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTC
+
.1$4G.0.?A0:CH6(E!0$76$&(A*#.?.+G:('!2!<16/B@/H;@;69(C+A6G9);A$!&91&4%1-*;&0?C$:#".@
@r3303
CGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGNAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATNAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCTGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGAGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAATAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCNCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCTGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCNCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATNGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCNGAACACCTATTTCTCCTCACTGNATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTNGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCT
+
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
@r3304
CACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAATCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTNATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGNAACTGCCTGCATCTCTTCGACCTGAGCAATGNCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGNCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCNGCCACGGGAACGGATAACCTCACCGGAAACAATCCGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACT
+
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
@r3305
TGTTCATATCCTCACAGATNAAAAATCGCCCTTACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGT
+
.+''>%-3C*B)AB#5-7%GBB<;F/5GG<B008B(>(/@H+8A?3HGG.7-0.)D.+#!%7E<@CC+88H$".=43=E?,",$>H0=F(0H7HAFG>-;58CD72"#17!"4$/+;8=;'7DG:5)*?G<E2)=4AF?**D:"2F&>8@*9=.@;#848?09C<8!3ED9$?2"A(42/095/$D=8$%4+;'89
@r3306
CGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTANCTGCGGGGCTTTAAGGCGAGTTTGCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCANCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTC
+
1A40;>;*>!A&A:4@!.ACB;<6*..7C3!E3'<#@*G6!*"%'FC':2'>3)9=,$-7G7=B=%F4/46??6!CB:$8?7A54D()&96-%9,:.$<%,*&A73#.@!7+5?=G$54<7%EHB(?8'!65G,;$FFA+CC9"$%'"0&6@'*!<A?689<-+(920$>C)?,73<3;3*2'7"?B-2)$;1),61F*:.&#/AF"!A6!/5+H!2-1':@B!#DB9D@D570&/."7$3!+B91G7B4=**+CH(8-"HC2D0)>FD<2&,!D<5>'D>+=+;;
@r3307
GGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACACGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTNGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTANCCGNAGAGGNTGAATGACGCGACAGGAAGAACTTGCCGCTGCCNGTGCGGCACTGCATGACCTGATGACAGNTNAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTNGCGGTCGTGGAACCCACCGAGTGANAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATTTGGTACNCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATNATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGNCCACCTTGGATACCAGTTCGTCGCGGCTTTTCCGGACNCAGTTCCGGATGGTCAGCCCTAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGNCTGTGTGCAGATTAATGACAGNGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGNCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTNAACCCGTGGAGGACGGGCAGNCTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGANAGTGAGCTGGATACGCAGTCAGCGNTGGATNTTATTCTGGGCGCGAACAGTC
+
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
@r3308
TCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGANCGTCACCTTCATGCTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAG
+
'0.%A,G5>&+=F)0@FE3:9!=0E;0,!*:!9H!!0F.8!!5.0+.1A><'CB4#6F&92GA;>=CD=%:>92/%,5.&,"E/D-)?6%167<B-$DF
@r3309
TTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCATATCGACGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCNGG
+
*CD"CHC3<':3:#/G"@>>H8(HC#5F'G?0':G-E7/0C>(:3'&2>A;7!G5=G.,-EE"C#,5C1-G-@G6?%H?7=4<:E4BGHC(<!;!22-H<G+!8HH9C87D3)5B?@6@FD(95,D=+G'3&C?-AB'8)*4&FF@$$D*<0GA:A#7DD3G/5,+)@)6:.E23>&F4AC1$%*G0@B(?F(=G,F.A)8:2#?!*+5C@0(;=48#AE16"6*=3-#(>B7%C(2#.,'A/,:3&C8-(F)4DF;CD1C*C-CE$0G*)$B2H1F-?:#A',>H->1'<,)&=7;'E>@196!,:;9F9($F0(9)25%BH<C%<>:19+?!8=%1%6=50D)(A5.G,G;C@:G4">!@H0)'$0B(F@$#)4;)0'G$+24%3.F9@157B*DG:G76CC-<ECG2?(1
@r3310
GAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGT
+
+2HH%*!(%):##B%-15&*B573,)B&%F3)GB2*2?142*0;;D!99
@r3311
TTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGNAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGANTCTTGCAGACAANCTGCGCAACTCGTGAAAGGTAGGCGGAT
+
10G#?@42&HC@;&0',%7%*&&#+8'F11$($HH6+?5>15F'DE,DH!4'GC<@5@B;+"@0:2(-=?<5F',AH3;865%A>+!;2$C5.F/A!<D5/%A(-"/5*6>H.;F>9:C1F03%7G&%B<.3'G45H6.#0(A0.B#F0FEA&'=GG!==61%A+2%+)??86=#<F5<)5B@*B8C5"=.9!+&2&0%3.$@-.
@r3312
CTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCGATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCNTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTNTCGTATTGCGAGAATTTTTAGCCCAACCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAANAATAAATGTTACTGTTCTTGCGGNTTGGAGNAATTGATTCAAATTCACGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTNAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATNTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGANCNGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGTCTGGTGAACTTCCGATAGTGCGGGTATTGAATGATTTCCAGTTGCTACCGANTTTACATATTTTTTGCATGAGAGAATTTGTACCACNTCCCACCGACCATCTGTGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGNTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCCTCGTAATTTTCTATCTTTCATCATATTCTNGATCCCTCTNAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAANTGGGGAAGTCATTCAAATCTNTAATAGGTTTCAGATTTGCTNCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGNACTATCTTTCCTTATAACTTTTACAAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGNTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGATGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATANAGGGATGAATCGCTTGNTGTACCTCATCTACTGCGAAAACT
+
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
@r3313
ACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACNTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACANCAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAANCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCAGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAA
+
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
@r3314
GGTGGCTGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTNCTGGACACTGAGGGGAAAACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCGGACTCCGCCGGAGGGNTTTGAATCCTCCGGCTCCGAGACGGTGNTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCCTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGA
+
:-GH9?;DG)82G;(97'5D.(9:>5#:-#.>;?,15CEE$/*7+4D:>4'H>08"A.:>=A))#*.@4#!%%9(.0<#2C)!.%+$@&E%G,1*59=06;#+91C',!.6B%2.+.,*,@C;&4$D/<8.@.9A=5#88"H,2!43#&(&?B:$>G&$H+<!<5)"%9-)/35.>76<5!!>7E-&?>#3=()/D,$A?2<@1*#288;"<!=","#D%1@'$<.31H'B*/$:$G0$D:29:9E*G7$7=B=:
@r3315
CTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCNATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCNGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGNCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCCCCAGAGTGCCGCGATGAAACGGNTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGGAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAG
+
F.F8=D>//!0!?8B'"'4=7#B"!@2<0'(-#G#79!59E0.B#(;8=;6D5!F607,#8<@&'35B<%&F&C,!297G4C5)>955'4'$C!9-,.#B28'5,>;)-.F-9>;-A+EA!E'8':('(D,84E<@+8C5'3!?!G2?>1:;;.GA8*/78?44BE))60;@@6@6))"D/EA1'@B/?/B)2?21$)$"7&=C2E)7+@?8HBH7=B9E!516$3G(#7>B<3)'>DF<H*?4</;"6?/7D7#6*%9857:26/7H,5'3#5DG@-*<.(A*7E"4C(&;!H%2%!H"1$&=9-@?*>)F:"<;/:00H-D3%;:A#F1A3-=,;6F)CG.@<$C*27-03B.*C#'6EG#/$*6DD$/*>B=A36$57.=!2>%#$'F*/979,;1'2$BE+4B?&*AC<0H*H)3>4(,861:'09)7""E<7"DE5(:0&C<.-9-
@r3316
GAAATGTTAAAATTGGTTTTGTAGGCCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAA
+
BDG>++$8B-4DEB:A<E1-CG(9.BG7(%&&=&:((H$56G-BD85%HH3AH=4><&AGD*(D#/&E3:F0.56)!&'7%($!)?73!>;BG:37B9=,0;6.,G52
@r3317
NGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGNTTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCNGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCGGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCNGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAAC
+
!E031!6+BB$E4,/D*#BD&;1.$,$0CAH)'5.?5/-3A;)&$?*)%&/(#$0-=#($);6%3+)&#3221@)H6#<>*#A%*&!.-=D7$7()9&)2!.B:;1!12,9,<A.BF3F.H6:+8/>4A.'+"5$4?B(0:0H.'-,AC2*(02-5$!0D4C!.<E+&=4CC</GH?(F$>D%)/='8>C10#D!-$G/.&C:FH3-C>#0&%?8(AH$,)82*F?6234@#.*0,?,8,@F3$:,1))E;(/&4?*/H=H71.4%@D;-,.:/75DE!&9,B,>1:0)7F"<3=F-0H(8*E+H;5*,F/""=&2:>1H'H87<16&8/B0;3#A@>6*AF'"+A7D5-@BA68*1/<1+3,&8>1GE'!)A@@.1C("$/&;;6=6#@4&3C640?;,$D4*10805$+"H"4$5711+*G)#9G(%!*G,F31))#1#1H1<8?>EDF*?#HD"F&)
@r3318
ANNANACCNNGATACGTNNGGNNNCACGAAGGATAAATGCAGNAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTANANCCCATGACACAGACAGAATCAGCGATTCTGGCGNACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGANAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCNGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGNCGCTGGTCCACAGCCACCCCGGTCGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCANGNGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCNGGGGGACGATTNATAAGTTGCGCTGTGTGCCGCATCTCACCNGGCGGCGCTTTGAGCACGGTGTGACGGNCTGTTACACACTGTTCCGGGATGCTTA
+
*&%)!"&*!"))"))*('#'"#$!+)+&#("$+#"*++*#&%$"%"*("*!(&#'(#%(*&%#*+&)!!!)&&))&!"&%#(%(#%$&"(%&#**%!$'*(&$&%*+&#"+"'*#%$*!'*!$!!+$+%(+%'!!$+$&)#*(&''%)('#&$%)')+#!%(()'+'+**'&&)$%+$()!'!*!$)$((%)!+)")!+%#%+)(&!!%&)!!))*#*")$"!%"(+(%%!")#"%!(+)!+%"(#$'$##'%(!$%'!&+')+)($(++%')*+&(+&'%+)('(*&%&(**#%&%"("!!&'+#'+((%$&+($&%+(*')+(#+*$&"#*#*!'!$#+")&+#&"''&(%!*%("*!(+''!#!'%(#*((&*'$(&$*)")*!'!($%%#'+&*!*'*&"*'&&+%+!!)'%*#!$'+")"""$&)+$+*!$($&''#($!&#!+*+"%)*&%#)"!))"!&(%$$))"('$&%&##$'&!!"'!"+')*#***'#*)**&+&!*$+
@r3319
AGTGTCATGGGATTTACTGCGNAAGTTTGTNAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTGCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACTGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCG
+
(69-1F<!%>H$9);<'D2'+&7#5!7>==G60;.6&#2'>8G)"9"7:3:DE'";D77H0?78/45//H':%"0@GBB"51'2<*A>>,CG'+H,%(#01';%-=D+7>.75$12"@6=;45;@221+4F#$/4G%0"&D&#,,4-$2-E,?3EC&E@7"C+,@5+$4>0"8DFG7AG@%5:.2@;(@//+-*F5E#,7#!/%47=@(F(2$&:&;G,1%&
@r3320
GAACGGCACCGGGAAGCGGTTCATCCCCTNCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCNGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTTGGGGATCACCCGGAACAGCCCATGTTTNTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCNGCAGATACGGGATATCGACATTTCTGCANCATTCCGGCGGNAATAGGTTTTATTGATGGCCTCATCCNCACNCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCANCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGGCAGGNACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGAATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCNAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAGGTCCAGTTCCTGCTGGCGGATGACGGAGGCAT
+
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
@r3321
AAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATGGCTCTTCNGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATGTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTNAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAA
+
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
@r3322
GGCAACCTCATCTCAACGAAGAACAGAACCCGCAGAACAACAACTCGCAACATC
+
+F.2AG;.FH8$FH;34).;&1+D;2:#'-<.@H<;+$@C5'.><,+'=>D8:8
@r3323
TANTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAACCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTNAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTGTCTGCGCNACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACNTACGGCCA
+
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
@r3324
TCAACCAAATCGCCCACCGANATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATC
+
;$D79E!5,A%AE.H.#%G@H'8!<C:D43%&*3A2%7(#E":03GG3*!341B>?A85
@r3325
TCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCNCTGGCATGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAATACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAANTCGAATATTGGTTACGTCTGCATGTGCNATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGNGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGCTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGTGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGANGTCTGCATGGAGACAAGACACCGGATCTGCA
+
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
@r3326
GTCCCTGGNAGTCGTCGTCTCTTTCATATACCCGAGAGTGAATTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTNACTGACTTGTAAAACCGGTCCGGCCATCACGNTCANATAACGTCCACGCAGGCTCTCCTAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGTCGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCNACCGTAAACGTACCATGTCCACTTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCA
+
<!H5FGH#1B5)!*21;2HFD8?>,+-+D%47@F'+<@*8"4(-5?,0;049*%44,#/:0*78?B7?=68$)G/&)";'C780@0.(@?G9/=F>,(1=%)1HC"3@'1<H5(#)(CDC<6/'<C,%%%?@2=&86*!"'@DF4"040:.4GA%2@A@B7=)'9<BA,6!-(#*/6?##"G9+."H>H2+&6*-=16D9*20E'"&5/0--#,4=#:GBE#'%G0/6?FA05DB-?9H!,)'<5E9%&8$9<>@3;1)*#21(':<?5CB0@AE3D+8HA&42#46<C=*8:?"?'4-FAE86>2!A6;;7:(.99E''H>2C&"!65F7D1H+.*:+(1?F81CA56A+H!<==!:-29<8HC.CD+%0"(3B$%7FF;.64+7%3"(1418A,&H+)'G#?57&'71A')F20?=1(@'.2G1-D2><75"+
@r3327
GTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAANACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCACAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAG
+
9>BC';>D8'4'2>:()D738(>:H?B!@AC*;17.@,+',?$1/G;2<2)((@*3*1FB?*F-4(8.""2(/,>-'#7=+!#*)2?<H3!#HE*?GG1H.?1D8.=.CD:B<G@!G9$4!,&%6#6)+@4,&0CG860?A<#)+5</G%()#EA56=,46F?6!1E&?/>6EBF%=5%0,D$0;*/E,G@82,,H87#@"%@C88AB,'B1&'/9H+/!24DD:97!@,G4H)#
@r3328
GCGTGAATGTCAGGATCACGTTTCNCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCTCCGTTCATCAGTACTTTNANATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACCGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCACGACGATTTTTTCNGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTNACATTACTGAGCGTCCCGGAGTTCGCATTCACTCTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTC
+
*+%!#"%(#$%'&+!*%$#"&$"&'%!"$()%%('$$)"&#+#(%!(#*%"""&+#"&(*+$$#%)')(**('$)+$('&+)'!*#&!$)*%!!*(%!+$%#!!!($%'*++*$&*'""+&)&+((%&)%+*%+('##$#"*$)$&')*()$%()'*)%)(*%+$#%)$)'+)+!&!$'&*$(&%"'"*'+*#(#$+#$"&*'+&%$!(&"&)$&#$#+#""*%+$+(!#%$''#+"++'")"(#$#()#"$##(#'"&#*!+)!'&*)!')*"+&()$#(#!$!%$"&%++%!("!&!%&&)+&#'#')+')&'"+"+("$)!+!"($!)#(%'"''*)&%'*(*+'#(%*#%(!%!#*)+(&#%(#)'#''(*$+'((!+&"!*!$("%(&%#&)&&%(!$"!"'''*&#$'*##($*))"#&%&$#&&**&*&!(#&)+!$$*+&*)"#"#!&$$%)*"''!)%$%!'%!!%(&*(*$'!($%!*!+)$$%(+##)&""'+)#&%(*&&')(#(()*#*'*)!%*$'&%%$#%'"!("+$(%(*(!'*$%)$!%!!+(""$%$)'#%*)&")*)!*+&)*'!+$)))!*$)"&'*'&$!')("+!$''%)+#"'!$*("*+'"'!"%&%(%##($*&'$'$$*##*&+&*"**#$")*!+#+**)&$*((#%$)&**!
@r3329
TCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCNCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTANTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTNTTAGCNCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTCCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCCCGCAGTGCCTGAGAGTTAATTTCGCTGACTTCGAACCTCTCTGTTTACTG
+
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
@r3330
GCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGANAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTAGGCTCGCAGAGATAAAACACGCTGGAGGGG
+
BH2):->?!=D0,&==29<=!H?$9?#(#0A88;5<?)0G%?*-<D:-.<3E-2+E<#8$85&AF8A#"H+/A>9E%&CF1G?D/7-?.#*-6956&'.H(;;"4+FG&4B)E:756&'@("2B<)D:A1&>!&7+(57":$9-F(E=92B+("3F*(.*FG""@,+-%3)>'!,"E;#@E41AG=80)
@r3331
CTCATACCTGTTGTGCAGATATTANCCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCGCTACCACAACGAGCGATTTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGNAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCAT
+
D,'15HGF>804BBE1*&"-.%B<:7B6?+70@1/!G*;#7F*#(=8<F!0AG$+1&=7%"%.#F?/<@G@!/=$';/@;&%)9/C<1)#2'D8""DH;B334)?GD".5-B+51/=35->;(/E#CB,678#1$>C1*30H%0%+/6@G?.&!?@.8H/H*615>?9*+*,#";939/8D91&3/51!</%&.!>?,/&A%>@)>D.,>.H!D!475F:+0)CECGB30*1CC!:%8C@E&(H:)6A=?#<#7;D;1'1?7EA!:5??!H1/</-H,1D6(("&:H<16.<-$HE2:.7',F2H7)<=.#D&$581E$'?'8'74!#D17%8()%%//H&F
@r3332
GCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGC
+
6D=3'D$,A@E%C+6B9#2)C/#E(G4,"=E#(+5FA=/(,#<4B8,;G)?A;E9##6H;16D4515::)+60"59&<A)D%&H<GA3/09*(F*8.G3289**@'/F$$
@r3333
AGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGNTCAGGGGGCTTGCNGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAG
+
3C>;##*C:*B%G/H.@09<1<889E&FDE!)>#=1*;HE2),2"=1F'19362B<@)$1264.H5<@B(7<@,A939/0>1<=D522D?<2G7:.+B,&="6(F9;-H?=,2:B2-6H:C@=?2>?FFGB5(&:$$?/9+,8'G5%;G>;<%D,*CA86?5BH5>"-1"A.0C!&F7C-5=A:-=#H/6%6=&2.E2,73(G!0=2".7*F/=G5*=%3;("%<<;#)?<>FF=',G$#<;6C:C*8F13?),=HE1::!#5'F89#A6<?9ACFA=EHB<0(5<3<&=&E2%98033?HD0?&$8:9F@%&3)B&E6C8*7%7?G+-<B<-E%7#5!$&)/1+7H.!H4A=0'C,//5E7=8;@=)25G$6.C"8D<G//!,=$07D3'44-:BD#F(#G;'?3-
@r3334
AGGCTTTGGGGTGTGTGTTACGAAACNAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGANAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCANCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAAC
+
-=!0*&G11G>?>G?H51H+E.5+5%>7;28?5.,8>';-%/<7@&8,8;C2<#.HB?/+7C,;%%7D,%/.59$2'>*0D@"(2:.H2.D9&>8E,4F!):8.%#*B942>.$A'(3(*%?B2D8E8738?@6#52'+42F5#B1-5#.@A2819%E"+;).,5D<D%>)7;A%H9,+H@1)F;H8F%?'G(.0?#@@,#5+83-3'9D6=8&3=04/F?92CH$%EEB,=.-)HD&3#;*2(8((6<->>D!E",.F!$+10!7&:(5='?8*??&.3>9$F%51>*=09!>#B550!):$#)>#10'<C).G2441=7%&CD@AF)>8&2/+@<9D%@@*&GB46<&!/38,8&#B#2((.0-$!+H3.%-:H9/!:C1D8:=5A$HH?:AC@$&19/#B(C,240H50G%*59$
@r3335
TGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAATCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGNTTGCGAAC
+
5@G@1EF9/5,!B;'D6$:;,;<0?<!;%H&*0:HH<)A)%<&?%5H@7BE0;:+66?&<)38>4.4CE?$<>97!,"<@D3-3DA#H(DF/)),99*3%(-/=3309/,A>16"HG8>5,(<67)*2CE3+&?B2==>.1';H..2).,!33)()$)H=A/
@r3336
TCCTCGGGATATTTCGCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAGCTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTNTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGGACTGTCACCGTGACCGATGACCATCCTTTTAATCGCCAGNTAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACNCGGCANTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCNGGGAACGGGCGTTTTATTATAAAACAGTGAGAGNTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCC
+
#$($%%*)!&##'#)$"+()$$%#$%%%(!"&"'&$!!'&$&&*'%+'*))+!$+"'!%+!%+!"%)$)&!+&!'&$&!%"&$"+(+'!$)$)('*''+%!&+!*&#)$#%!!)*&&((!'*#*&!'()''*'*#'+!$+!!""%%++()*)!%&&&&#$$&%%%))'()"!!($)&$$%+$))"+"%$!#('&"'*")&'+*"&$!#%(*+%+(+*%)!+#$'&)!!(&'&!&*++*(+&)(*!)(!**+)(%)&'*$(&*('&'%'"$*#()&()!!$(("(&&"&"'("&'$$*"(%"$'$#%'!&$)%*$+%'(!$&$%'%!!)'&&)'!'+)$+$!))&#'"$('*"$*%+('&!"$%"!)%(**+"$(&"++*&')%!)($%%(*(&($"&$*)#!(#*#++%+#'+#)!%%+)#)&"&'#&"+"*%+&#&(%$#!$(+!(#*&!"+!(**'$&)*)%&+($%+!%'%)#*!%!%)+&"+#&&'$$!'("'#&!'!(#$+$&(%)"!$'('!!(!&'#&#*")$((&$$('*"+&+'"!%)%!)()!#)$'#+&%$(((&$"!$%)'%'(!($$*$!'%'+(((!+!)((''!$*$&'#*+'#$+#'#$((($)#$+%*#"+'%+#+*"*%)!+$''%+)("*%+'))+*))"$$))$'%+!#)(&(*(%%'!$#))%"$&+)!"(&"
@r3337
CTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCC
+
.6!"G96#%!%3@>FBD0/:"2A:-@,(*.8G-55C@A?C*9;1:1@&:@*&B/,F<694!,8@?/9(!7.0%(;99#+1:<;
@r3338
CGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAANAGTACGCCGGTGCTGGACACTGANGGGAATACCATCATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTCCGNAAGTGAAANATGACACG
+
?$#%BCDG>+8C53-$):=/C+;F.;"7'%24G-;:B$DH7G.&8!;+#GD%:@6@/'1)7D>*/:.137216=*'-F*3+9H4..?.H!0@!A/A#G2*9!7:%H10;*-65;@,>-*>#:;(;%?65@)@A"*7-10>)7,?3'<.&4>H-?0$G*G565,21+69=!&04H-C@E)&(><127,;"/7E,*B7&HDH%/"A)C@>(BA:H!#(G:#>/E%@;35)#.H0)60>4<9/*8".&1#C6+:#/;
@r3339
AGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACNGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGATTTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGT
+
AGF=520C(/3:5<<?HC"'/B"D)76?!1575<4<#9>8?)"A)@8$8+/6&838.DD%H#$>55>3<@5$A0+*$H7$&CE7#1.B)C0$-2*:@E3F790B#$0)B2:4B$G-%E.HF)A&F0$=D9"@2>:)$G5=<%!*$E'*?")2$0'/;=0<05717+?4@"-)3G-=)H&6G0!#)=/%D5A,24D"&%FG+F&(;E3-.8:46"6-!?<572"8@&'(9)H@&?4AC%:;(F.ED'(>$E;4><H.@/;5'AH?/-$,$$6H$0G9%*,)7.$44?D9H?F<%:4?"##,A$;2:&*F,!6AE!$C/
@r3340
GCCAGCGCCAGATANAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTNTCACGGGCAACCTGTGACGCCGACTGCGATACCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGNCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGAC
+
(81?5*A)D'@=?%H?G6*;3.0:!BB#83H?>+:ABBA"'E?&@"@)*@#:/AD!A;..7)D-D-8?#*'<-&DB">8A*:FBD*@(#&!<$8,E6(HD.</218;)%0A1$(H,?7;!*#/.6'H=/)760#EE",CB#,F>%5H39>3C5(-%0(:4D$@).=;$(0B=2=>/<?B52%?6!*'''E@%;EBD3>87%$8B"C3H(.C?,0E%<1512/%B;(:F.9H8'1.4/5":BDD,5*=)B?)H>$#3,1G0EG'+6<)!CE5%G5%C'1A14#&.0):./<3A
@r3341
CTGGTTATGGTCAGTTCGAGCATNAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGNTTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAA
+
?(3H5%=/7??,B#H67A5@4B(0A65>'D:F</('C@C,*%)#+5G&+(;4'&H?.!3067:&>&8105)!G+D;.*$4=2*?!&3?D>-!/-53*1)<':=?'6?/"DD!:../4%'"2F1.?&,;B!(8-B*G5@$A4:(B;83#!-&&8@3&=,3#-&<93!*160<E.":21);,2C)>?4
@r3342
CCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTNCTGCTAGAACAAATCCAGGCTA
+
8<F934F@D7)-D84158BF825@F+&5-13!1;@$@(*7BB%0C@3+53E/$G))<!',$!--657'557&).6(23-5;.$<1D-(.+C-0&,:7;4GD!.,7@<A5<"=-:9=0E5@>F8A<(E)E9F/!DC:'!D-E?
@r3343
NGGCTCTNNTCNGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAACAANTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACG
+
$&&'((#%"&##)$'+$"%%(!*!$((+)*&'$#+!$&%%"%+(*)+#('$$()"#"%*%+##'$$$)!+*&(%!%'"!&%$+!+(&+)#%*'"##$%)+**%(%!+&(*'#+"*&%$%%($"+()%"*%+'"()#*&$)!)%"#+%')%!($%&(*($#+'!&&"''%(%"(++!!+#$*'*+$"*#'"$(&&+&+!$)*(
@r3344
ATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATNAATCAACTACTTAGATGGTATTAGTGACNTGTAACAGAGNATNAGCGCAAGGNGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCANAAAGCCTCGCNATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACAACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATNTATGCATTAATAGACTATCTCGTTGGTATAAACAGTGCACCNTGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAANATGGAAAACTACAATACGATGCCCCGTTAAG
+
?,C+=HH@/9E?2(D9#-=B)9%.)-G6((C>)9:78@C9!#(#.:G:)&7GH1-AA>A(3&@@.5B/1<96$7F+H2!:),6@<+<+'1!$G#%9.0$HE.;E'?*!9BC,6#>>$&G-74$!,@2C;H*4!#+-)6!,!#=B?><:557/"47A=D8>:96=@+#2&.("'6#H=,%E#@AFF&E-#>"26#*8&D"=2+@"?,H,.<=C63@-H2F858,&,D>9%:,2F?2-..59C'<$7!%=G15/BF,8A/5#G)$?*G9H:B.(&)&=4!4==H8@*'=$&F'HE)E"BA:=+4:4:0!*-5)'@9"'=.,"D-/!3#?&#@'+:?+?;F(=3)34;G.&$.!(:G&+>;*"@-3F0*H<F)DB;$3-'5&A1*7F=)?9"$&4@A1&D@%*>B2/5D18>"F4)<.@@$&,6EAE!5B:*A'E$@)*-@1$GD3#HF=>F.CB,;@)1G!!57H(>'E,5/%$A8!&:<,96041.A0%@H,E-.C*&A'//-+C&C>H!7F:23A1%#;)#8?2=6#"%?-/-="(GGE"30D;,=%,>!"7913&/&/391:46C10G>D(;(!DD29!!%4%'C*4';%!
@r3345
GCAGCCAAANTTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGCGTATTGCTCACAATA
+
5&=-#,E4';E:63A<2>$8'G8C0('2-+429(*(?:FG)1#4<1@(#B:>:0.H-?%>=*5'FGC:<>&GG?*$><:GB,=-C7;#566!.A;5'--$4GH:+'4B>C9."'*&2(4A)%/@&36#3HDE%=
@r3346
NGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCAATCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAACTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCNCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTNCACTCCN
+
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
@r3347
CATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTNATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATAATTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTANCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAANGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTT
+
3G??+#0+/7<?:30%A$4?1+:#;#A'2D4*%-<01!9?&1F2!06;G'035AG.8G7+E;G!&/((<E)%1=H*30/33@GF#@&;=E/C5:92'2%4)B498";3?E(.)&":D+GC37+@'D*8507#$G*C((?=!35*8E#+#C@=)*<>F62(6H/8=**?D:93+!8"*C9CB797C*;@%F/%>:;,"1/."A./+)D+F(;,>%*7=H=0>C(+91&9/',$;/0'<@0#2B2"3ED'04;79#$14"0&<<H#B?<490;@6<@1@7/&'7G%#@BE&(?.>.@;90(.":@5%G,#"8;E*5B?F1?<%&2:C<.G,@%%GCD!*&EAG$=/5.-#--6"%)(6';C?0+0:4C?!6(,BG2G!/<;?;C*:HAGC:(5.:E><43!=069-<D!9<)G46-&6A34B?>#AF=,0'G.91%
@r3348
ATGAACNCGGCATANATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACANAAAAACAACAGCATAAATAACCCCGCTCTTACACATGCCAGCCCTGAAAAAGGGCATCAAATTNAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAACTACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTT
+
'*'*$*%%%'%!'&")"+'$#&)($$%#%(+(%%*+*+'''))&+%)!$*)("'*#&$*!*!+%)$%+$!!(!*)%)(%(")(('('*&$(%%++*'*&#!&*%"%*#(&))((!$)*+**$$##&''%!!+""*"+)"+&$+$!#)&%*&'#$'('')##!&*(()'+($($(%%&""&+')""%$'*"+%)!'+"!%('''(&'($!'$&%!('#)%!!*+)*%#"&()*'%)$&'%!)+"&(&((#(*'&!#)""#!'"(*"%)''&)*!%(("#(#"&%&)'$%%&*%)#%++"'"(&$#('%"*%%&
@r3349
TGGCTGAAATGTGATTTCTCTTGATTTCACCCTATCATAGGACGATTCTATAAGATGCGNGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTCTTAACACGGTGTTATCGTTTTC
+
+(('(+!)"&&)*''#%)!''"$+*#("&+")!$"'$%%*(&(#"'()##"'%!%("&'#%$%+"))(&&%(")+"#&($)++*(%$*&'$&('%'(&&*'**$""&$&"**$!#!(((*#'&&*'
@r3350
GACCGCACTTTGTTACGCAACCAAGACTATTAAGTGAAAACATTCCTAATATTTAACATAAATCATCAACAAAACACAAGGAGGTCAG
+
G/,&H%=BD8-5)(;E4"=2''C%!0#;H7@!-$BG(,&F":0@F%=@!01?8?3-(1/:&H<$(!H0)GF-F:$43D*1GH*'C44"
@r3351
GATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAANTCCTCCTCATCAAAAACAGCGGGGCGAGCATCAAAAAACGTGCCCCGGTGNCATGCTTCTCCAGTGCATCCAGTNCGGCNGCACGGAGTTCAGTATGTTTCATCGCT
+
?>BHE=&)554*G*=,G8(<:7C(G*1.64()4!+?+@)<B5905H4#7';9B3#5>&0<,2,+,#43849/CC@AF);G!0:C/#>./=2<8A.B=$=&)2<4-6:(!!<3F#5F6G!;2FGH'4+@+%$A=AH418$4'66=+,C)>:?GHG(9#2G4*8590!/>*C'<..52=#B*DC7$#%#)CE91@
@r3352
TCTCGGCATCACCATCCGTCGGCANCCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTNACGGATGTAGTCGCTGCCCATCGCANNCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCAGTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAAT
+
F/+)(#D9H5E##?B"..*=>$C'4D=1)"18+BE34,HF8D2%1<;(D//&&8EA8,)6H!%75:@C$C-)E6.##4&#-*CH(=C.64>7?)=,6)4D":7,+D"0(,*(0.7<#H0)'+)G?-+E&E2FBG>A>+-%H'?#"G+@':,H.+8=,/=#:/4F$6F/-&?#F'C6$-F0C1.G+1-05AH&6@*H5/;-(,;-)A#+&6B,+H!:EE8A,("5G+:D2@@-D(>7">,?1#&<-A%)A%@6/+C'"=*2DA#>0'&>EC%>EA6=E&D%H%-*CH.'C$CG8@'=,?31
@r3353
CCCCNCTNCAAAAAATAAATTCATATAAAAAACATACAGATAACCNTCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCNCTGGCGGTGATACTGAGCANATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAAGTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGACAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTANAACTGCCACACACCACCAANGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACNGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCNCAAAACCAGTTAACCGCCCTATTCTC
+
7<&$C3.<F>=,+%C%)@-H<9=9"7-8%2?2*5=7<*C7;B1#(-?D"5FC"(2-($'8=4D,'CE00D0*B:1+2+G1)$*B@,C%">C188&C/?<*5//@)#FF;7?=E9942'2%6%=4?2A%?5=#,E.?G2B?>2+;@G&'!9#;FF+%4:5#496<G,HB18HH4'0>3)'?7.$)2$-.,87+.?B;E(#67C15'5277&$9+'H>%=F4<348C!265=CC@8">;8H?5("8A$,E(#)68!:178175>?F0/?CA8%C?0#)1&%)2/<)G5D%@'GB2;%93;+@*$E+GD.%%G,+H4B"807D>9.?.A*!-421*"7,2048<0:6+2(E>F*H&/:":1B&3)G<0:82;$,'G;-)0B(?&#!*#&4E(#1-'2$D"888!?,;5:D%8+";C<2D,+=#:A(>,()A6/*37'A!D6:)'.'#03
@r3354
NGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCAGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGNAGCGGTCCAGCTGGGAGTCGATACCGGCGCTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATANTGCTCTTTCCGCTCTGCCANCACTTCAGCATCCGGACGTTCNCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTNTTTGACAATCTGCACNCAGGTGGTGAACGGGCTGTACGCTGTCNAGATGTAAAAGGTCACACTGTCAGGTGGCTCGATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGNAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGG
+
&FFG'!:-F343@95$%@5"<9%38FC'+!;>;D(;,%7:(G!0:=3/C<=.>2&""5.DGFB3AHA:-&!?#FFDG(8H3!4?&0B;@%$#F@%'(+2*HD%%;,099&5!095$#09H>A>!B7>&8C(EH$F&.8,H'5<&8';'!!2D>$!@H2?2G*!A45>6@G.97=+/?!/7=8#$@<2*&1GF&E'=AC/'0';8!C9>;:H52'E&-90.1'F:G58#00<(B3,1)#;*.8B,#8&/7-@*'!%23(>%F"6G!:-EG/":,+,%()2&G.':/?D#6,%(G/)$0D?6.0H5:"4'-A@4=G(C<:<3+;')1%C%5?+FF&"0&*'1G)$7**=*%5'8%H+(:428G$+DD'8B%6!+C"?>C'.-,?.':=7%;H&?6B))>@"@6*)-%'*66(,),7D1H**8:%@.A$*+)&!>A>6?+00&5CGE1G2-#8;(48=)GA=8%CH.;"3B6:=8+A>7&(<".)>-H,.)"A0?5<)>?9%&!6>D*E5D$EHE53&>GE.8
@r3355
TAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTTTCTGGCGATTGAAGGGCTAAATTCTTCAACGTTAACTNTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGAGGTGCGTCCTCAAGCTGCTCTTGAGTTAATGGTTTCTTTTTTGTGCNCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTT
+
5G90%+GFEG4$80<B=3()=BAG$H*E-D(-$=,;2*3D>F+7A%&6"B,%,#/05<>1C78C!>4>F3+*H(H++C&!-G(AB@G<9%6$;C(B?H.>7(C#D7'1-$%<&(=,H.G>)=)@5+E!%.&402>H6!7+7+:D2%""GFAC6?:.<$9,0($&G7D<88+HG;F4:!8,#B,+?.F?64)#(#=+;D77<>)'2>)$&&E+24-2E0%/D>D7./C),8AE+C<5>3+3B>)400@B%=%H=-?2.+1;D6)+C#.$5-%9?%GHG"=.@?618,E4(745::%$F(.>?$<)>/19%:5#0<8"54:>-A:C!!.D'FA'=9912HE.)E7"((D-1E%0)
@r3356
GCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCAC
+
&)41#,B1D.'/9GE%;C*1$C+:+AC+4:.;005<0A1"1'B!C6>41/82B<:GE$+40(!<GEE)A1333
@r3357
TNNTCNCANCNACGNATNNAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTNGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGNATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGANGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCNCCGCCATCGG
+
!!!)!$%%(%")'("#(!!(+&*)&!###'*##+&)'++&!%*&%(")%+#*$%())&($&+'#)"'+#((#&(*#&+'#))(!!*'*"(*)!"!&#*(#&'#!*&)'')$&%%'!%!$'#$+%*!!)*#$+(*#&%#(!$&&#*()#*#%&!(#++'!&'&*'))+$$)&"((&%**"(!"##($+$%%(&$'"+&"'"+$+!!**!&#$$"'&$&&#(#$+()%')'&$#$&"!($)#)(#%!!!$*$)%'*"(#%'*+#%!"!$**+'#""&%+%*#(%('%)'*"+!+&")%&"'+*!'"&(+**+"()&)&*+$*!()&$%'$'&+!)'($*#)!+(%!*((%%%+"(#&%!)&!'"'"#
@r3358
TGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAANGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTANAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCNTATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATNTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGTGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTAATGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTNGCGCGACCTCCTGCCACCCGCTTTCANGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTAT
+
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
@r3359
CTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGNTCAGAAATGGGAAGAAGGCGAAGTCATNAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATNACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAAC
+
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
@r3360
GNACCGNCAGTTTTCNTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTNATGGTT
+
("'!&%'++%''+&"*'")&'***%"'!"(%$((#$&!*'#'&##(*%!'%!&+##'
@r3361
CGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCNTTANGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCCCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTANCCGTCATNACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGNATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAANTGAGCAGAAATTTAAGTTTGATCCGCTGTTTCT
+
7F($F'7G<+@8>+1H4B07+53#,GG8#683C2DE3/C"B%B3$-%9!1>&=H,@!9#>%'1"<:)H!:;B!G?$>)5GD@G+@#"E@';7D++HE':9)&?D65,/@&0EE?*>2E(7-G?A2$!C,&3-3?67E(=0'>H&>9<#*<004:)=3#H.*D>7-"'-3$*HE2/";!+#(".;21@6#=0*#:3FB&.G=G5F4>!6$.2%7:15$,A-5#45:';!F2@<02;<-0:HE&D-(G+#AG&)G'%B6:E2?+/GD+1$3;6E.!C-?!2"B"D&!DG!@,>'+G!+6F
@r3362
CACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCNGCTGGTCAGCACGGCCCGGACGACGGACNCCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCAGGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCGAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATNCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGNTTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGTCGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGA
+
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
@r3363
GCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAANGAACGCATCATCAA
+
@##>BCH2;84G$$*1F!C*.E0F="1>/&1*2-/!A2?3H@:&2B=>GB7>,!$CH-.)7)7@#D1A+/
@r3364
GCGGCGANTTCANCNNCGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTNATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAACTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACANCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTNCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACAGCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCNAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGNTCTGAGTAATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGGTGCATGATGCGATGTTATCGGTGCGGTGAAT
+
")#)&$'!&*%$"*!'"$%$+%'*"#('#*$('&**#"*)%"&++"!"'+&!+#)!''""+*)%!+&)+$%(&+&+#(##'*$(#!#!"'!**)&))"(%(#&*!#''&++#'!)*%%#$&#+%$($+#"%*&&$&#($#%&&*++)#$""$((#%*+)*$(+$))+!$!#(%&*(&!*+&*+*)")$#$*))!(%$%&#"+&*)&!&')%)%))*'+""'&*$"!()"*#+)(&&'#!%'"*!!$(*#'&$!"'(%*$!")#"!%!((&+%&&(#!$)"*#'()&#!!'#)%#'$&&!'*)'!+"'*'$"&%*))%+"")*+'""(#)!!$'(#!!$'!!(*&'&'%%"(#*"(+"'&"'"%$#"!%*!+!&%"'&!%'*"!'%!#&#)$#+&)#%#%(%(&)()")#'!("#*%&"&##*!'%!))%('&*$$&###&!"")')!*))(!"(!&*$'&(##"+%(#!&%!((!%$##+*&)$%*(!!(+!(*+$#%"!+++&)%#%+*%'#&%!')$!#)%!$*)#''+$**#!%&'#&'&!)#$*+"(()$*+$#!$+#(*&"!+++!$"!*)*
@r3365
CCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGG
+
=#1B/.0%EA-19C$,./;>><&=2!C:*10F@"4@""30
@r3366
NCGGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTT
+
'%"$+$#$)''$&$#$+*$'!+$+'*$!+%**)!'!%$"))%
@r3367
NGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCNACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAATCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATTAACCAGGNGATAATGGCGCACGTCGTTGCGTCGATTACTGTTTTTGTANACGCACCGCCATTAAATCTGCCGCGAANGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTNCCTTTGCCGC
+
"'+$))#'(+#(&+#+#'(%'%!(##&+&&%*'%!))*&)"%)$$)+!($)!)+++&+*!))(+!*"()!$#+(!"(#!'##!("$!%"%+#*&*)!'$#"#$#"*+*+%+&('%($%&+&'+$'()(&#$!&$&*&'!#%#&(!)&#'%*'%%!!#'&'$%"'+!()&#&'()#"!"!$$%)"!'%'$&(#&)#"**%$**'&$(+&+!#%$$("*$*%'!$#%$'!"#(++'$%!(&*%!+)$("!%%+)%%(*"*'+#+"&''("*!(!!**+))*)')"*++!"#&#***!!'%!+%&!('+$!$")("!!+"$")+((!&%+#())+*"!+!!%$#'+%'"'!""('!'+*)*%++#"(!%!&*&&('(%*+"$(
@r3368
GNATGTANCTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTNCATAGATCCAACCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTNCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCG
+
$)#")!(#%+$'$&!)'&*&(#')(')*+&'*)(*%$*&***$&&+(($%#!#&)&"$&$&)#""$&"%%%*(+%#(%"++(%)%)*#(%$%((%+'#(*&#*#+((())*(%%*#(*"$!("('(%!%&'*)+))'"+##)!'*"+("+(+(!$!+!'!)$!((%#($"$!*%!$'%&)#('&('!$"*(+")))#&*)$'"+#'++()'(&')%#'*)+($(*'$''))*(#%+%%%%+('!"('%*$)%"#*%"&*%"*)&&%%"''$$*$$$+$+%+%#*$)!##&(&!+(!*"'$!$(&$)&#&!*+!($'!&)'!+!(%"(#)*"#"$%#"''"&)$&(&("#"+"$!%)+($%'("(#+&'!*+%$+%%%!"%%#$+)"$(&++(#$(%#(#%*)*+)###)*'*!&%%')%)!"+!*)$'$*&+*"%%%(!&)()'"*'!&&&#''!
@r3369
ACTCNCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGATGAAAGCTGGCTGATTGACCGNCAGCTTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATANAACCTA
+
'&))+)%&*)"*%+!%"$()&%%('%#!!!&*%"**%&#+#$*!!"%$#&"*&%$'%!+!'!"%+!##&*(*&*'$%)+#+**#(*$!"$$$)"*#&!'"$&#!&+'#+$""#*(+!((&"$+!&$("++(+*((&(%#!&!#&#
@r3370
CCCACACAAGTGGTTTAAGGATGNACAGTTCTGACTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACANTCAGGGCAGCCANAGTCACTCATT
+
+&**(((%"$')+()+*+!*+&$'#())((&"*"&!+#$$!%+)#)'+'%+!+)#$%(#'(***&%)+)&*)*)'&*)*!%$!%*)++!&+)+!$)$%&$!$!*#!!%$$+(*%*#&$$!!*+(%)!*#*()(+%*""'!&!&($')!+%*#"&
@r3371
AGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACNCACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGNTAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACATGTTGGAACCAGAACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCGAG
+
>AG+%*1:>;96;B$E4H)E&0'40:B6:)*:(C5:E28!7$$/%2,"?B/AG/0D;-*1248=7E+G,F.&B?F863>B6>BC14DBG88(#)2.91@4)9#<A:@"%D:D1="D9!D)6':=F1//@>%6-@'=:+6E8%A?@'ED7@4@A#;:E6/E3!B04C@!?H%8:)&-#HD($A3'?*;C07,D>*D@:"9!G1/%C:+?G!2%G7$F@E.72F:)"9C#C)"(00#5$G5$=.5#A(?&%9)3*A"G+5EG?!)?053="+','"AE/F:AD!8$+$(3@8-!$&8"$$<303"DE="C)'%>:/9G&?-EG-8@6;*"A<9B*))5+0<6(1+68G&D%!*):G*.F?:B0GB9CG+2,/"@#3#A'FA-F=!+B?!F7/4H"*!.H/5-8+@8H,A<5(A6D9A/??E??,?@4+$,,GCE,#93(B"*&>E&>CA.H48>D%
@r3372
TTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGCTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGNCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATG
+
2A1>3,8%:@'6*==F+%(>!H@%"@5*@-CD69;/!3H=9+==F8C81-G(9@<CF?(1=H=.=0%@*;"'3;G';'8@-#%5)CB7A6D?75H".DB@A-9H>+")A.B%A9H2<;'-(#(=-#8@B,#D3F#874(H!;*!5<-/(<8+>(>9523AA?-90#H>#9<8/$0)+!':3-<=8,C(91',4<(51BDF$3%@:">C78C($@6/8A()('<,>8<D5D'"A@7HF.-'-'6=&="H-C!+C2F%-?#+BH#B47'8F9+C;3=/F28-<$C5,<4.:;)7$!!:##!>;5G1E26@&%&,A1@=A%&?ADB&
@r3373
TACTTAGTTNTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGNTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCANTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAG
+
HG+)*65#$<1467$7+>9#%;H'B+)4A0$4:2&E2:*+,>30/A3@$44D6-2EG=HA4E?))0'%,467?21/:>E%(2F&8GE#%HF=?&85E)4F1*';A095-%4D+9@+<227+A',),!G!A,4=,EH*=G-D#3(/->..G7<!&>)!&*1"%/G-(H>:.&A1'C/;980"G.2G2*0FE(%%@:&C%+60?@+)?4D(;7D=@9%1!427G523(>">*)%9A@'!?(%8%@GE/#?@6B?!#<4%/-G*;=>E'@BE;?D8#$*AE5#5,7/<!),<)8E7)2<;34/@!G082E%";"'1>=-F-(G8F6*)B,-66-H4'+@"@2;C0*;A",H4E=2!62;C@/61&HF223%F*"&<!5@!9<E>$=%84D5@7?/14.=!32CE2=E?*+<.5:+H/;"<
@r3374
ACGCATCGTTCACCTCACACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATCCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCNTGAACGNCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCNATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCAATCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCGTGCGCCACAAACATCGGCGNTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAA
+
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
@r3375
GGTAACGGTTTTTNCCAGCCACACGCTGCATGANATGCCACCGNCCATTTTTCAGTTGCTGAATAAACGCGCCGGGNATACGACGGTTACCCACCACAAGNACNCTGCNGCCTTTCAGGGANGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATAACGGGCAAATGCCCCCGGTTAACTTTGATTCTNGCCTGCG
+
5&8E.:2731.1+GF,C'*?DD,'-9,9"5:,-E"=%22$7.9=G;)/44**DEC2353)7!&1(<*0.;8F#BDC5*44A0;52!$$&DC=.=3'74&7360%D1+.(72A!2!,-E<='<>5D(:94((>=A&F4D&C$62B5@H?$5"A7(&.G*,#HH)>1>E1G5BG4D+*%>/+7CA3G4=9D#-@$/.H>>'=!*.H-,B)$A$=&>;!#-5
@r3376
GGAGAACAGGCCACCATCACGCATCTGTTTCTGAATNTCATCACGGGCACCCTTGCGGGCCATGTNATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGNCGGTAAAGATTCCCCACGCCAATC
+
G'*!-2E/@+%/%C8A:6B!!:)27G6@DA3E@.2CB;-10F100'+A&?!::E>5"=778D%,/>9!*!*B;7:6%A)-!'DGED=*,%4F%G#$18F3DF*E'28!#:>9(>0/9:?=#)?-$3:H(%&/#$F!,!554/1F;/H'(E)!7'B).:++*.4$*<:HB-(#2D00@B.5;$E"7DDA%6A?769+$!E*%$:C5F5)EA'5B4@(:A*(-62+5B)!:5>-D('8'3,((#(;52:='#55-
@r3377
TTCGTCTCGTCGCTGGCAGCCTCCGTCCAGAGCACATCCTCATAACGGAACGTGCCGNACTCGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTNCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTNTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATNCAGCGCAGTGTCACTGCGCGCCTGTGCAATCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCNGCACGCGTGCCTGTTCGTCGCGTCCGTGAGCCTCCTNACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCANCCGCTGNGGTTATCTGCGCGTTCACNTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATT
+
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
@r3378
ANNCCCTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACA
+
&%!%!+!++)'!*&"!!)"&&&%#%%)(*''$()%)+!+%!!)"$#$&&$)'#$((&***&+#'&$%#&+)&+&#"&"'!%&!+!('&))*#)()+!!#%"$&%"&"(!&%*$""*+
@r3379
AATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGACTATCAAGCCCTGTATCAGGACATGGTACGAGCTTAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTNGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCNATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACNGCAGGAAAAGGAGGACGT
+
:1>B58(00==HH%)*AH%&;H(&9/0+GE#1!64)--;6+):D(@*E,('8#+HH?+CE43,)8-=8E;9*#=538-&2%>=."@+99>/"ACC35-,FE"0&=81@/@99=E)F(G&-*>?H-)=(G*"2F>,;7C+2.'7<1:B@"/=)<&G+"1(,$'#;B5'/1?,;F-0H0;81:#@%AH?-"*;=.!4B/=1/"?<F/78B'67./0B@B+H1244-"?7E:!!;#.&*-(E,C*4?4H9/=HE!"F!:<E3259H<;.7BH-7)%4)@B&,#&?'-3.A1.=$=+%D/3H?
@r3380
GCNCCCCGCTGGTACAGCCAAANGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACANNCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGNTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTNTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCNCCGAGCNGAAATCGCTGAGCACATCCA
+
$%*))#$"$+*#+"!&&*%+*$%")*(+"*'!#!#$()')!+$*%$%+#$+%')!)"+*(#%'#'$'#%(#&'+)()&$"&""'"(+#'!(%#!(!$!"&&&''&(!""%)$$%##&+!$!&&)'("$!&"#)#''##&*$$(+'+&+$'++"*$("(!!)&'')'"$('"&*!*()$'&*+"%%(('*&#"')(('#$+'&&!!!!'!&!')&)+)'++$*+#+($*"'#(%"!)"&'#!(!()+!!"#"*#$$'+#(+$%(**(*&#)''"+'$!&!)##+#(')(!*'#*!*#)+%((#(%"))!#'"$$%+(+*""'
@r3381
AGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTTCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATNGACGGCAT
+
&(9<250F'B0<D:E;$(+("(+8'E@3==F6?2&/+,=!;DF0@"E'/;!17(9(#?"*D$*H+#E6G:!#.:$?E+AD*,0"."&H5@8#2@-)5!3G>=4.%6)2(7'?1C>+5#C=;6(>784.>!-A:%/:$0277B"1%?)+1="2G=5B>DB+.C"6*2843A$,-/27.:D@7>(06:/==)8(%A+B<(:5&=#A''<?<D!;-<
@r3382
TTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGNCAGTCACTCCGGCCCATGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTCGTTGTCGGGCGGGGATACNGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGNGNTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGNC
+
:-)D4<F)=-D;36-8*+D#@";5%3$=9?"E4FHDC74"4D4)<D%@?A7A3<E0"?:,%$&!1$)0G56*"*:$"!2;;E*"*8D2D4E+H:)&A.+(8&#>E;0$:</(2#=$$1D</),7&5+E..D?0/?.@$C!,4*/.A@7E:%DG<8$5'E"0'084;?-@.*D8'";33&AH;'@GAAH5<#4+E/2',2('*76B0*6/>,2<75$3-&.97!4F1A<;<''D=!&7.1=@4G-?A7A("5!GBC&,'H4%?+1<;H!!
@r3383
AGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCTGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTAAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGG
+
=1(%A=7-./:A8!)(:#&0CA4683?),D!(BH%;,4,5C/*,CF%/DA""=#05>6G(#9#%&??D40DBDF1&)9147#G"-/,&>!3%DG3$9.$$?0HG!(!$?:$519$3F45!0.9@?9&E.."#D9:@A!9H-*G#&BF("0;!+:.6%E'4H%&,5(:/!BA4"A&!%.0F-A(356F9.:+@G(95((.>DF:B.0##E0/&9*3+)BEE/;(%))"3%*)#"1$1F(+B9(+)EA"@+*7!2&/#60;(6'B@("C53"?B&H/6#/4ABDB*:<"D;5C7G/
@r3384
GCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGNGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAG
+
3H9/5:;+;#C5E7>C>4>=;C1*=>;1AE""(<<>3($.8?1'-"4-!="B+*97E7,D4$F;D;2-;$;AD14$990429B*).%@!2=%&1!,8->G;&?#@"@10+FG28(B2>*:E3,)5-D75$$$)5+8*/%?%FB)&!D:D'H?+1>A%";'FH>)HF*+"?$.+@3@&EC/-B)2<BB0%=F>+H2HG"=B&%DB*EG(A;35..99/=)2.:+93;0!F&+*9#(E08E(()+91+7D058@:C!&6@H&97?F@+H:@">F*8>!*07CB?+H%H6'>%;3<&&EG'<3/97,B?2D=6571G#/%-EC7&0C=*GG25"%6AGD&>"C=%?(=),.D&:E2"3*C))9#;0#)/"A7
@r3385
GATGNTAACGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATAGGNCTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTNATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATNGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGNAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAGTACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGNCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCNGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGGAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTNCCCCAGCACCTGTTTGAATCGCTANGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGGAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTNTAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGANGCTGGC
+
%'#("($'$+*!)#%*&)*&"&'*#!#%#'*)'$#+*!+!(#&'&*(%!!)$#&!&)($'+()&%!+*($)""!+$(*&!#"!%+)%$+*(*'!**)"(""*''("$$'++!""&+"')!&$#+)$$#')%#(+&"+!&&#%*(')*+!$!(&!!(%*%+!)+$)(*+&+%&!&*"!')&$)*)&*#*'%)#++#&)"*(!##'"&($%++%+)$&#$"%%!&+&'$$#'!"('#)#**($&&%$#'"$"+(&%&''#)$(+)%'+#('##%#%#$$)#+'&#&$%*'('+%"*'#)#'%$#&&%+!&")!++*)!$+%&)$+$%#)*$(&+&(((!%+*$!!)+"%'(*'("&&(#"*#"((*"+*!%!&'&'"'+!&+"&+#%$)#($#)%'#%'!*&+!&(+'#(+'%+$!)%%(%+#+('"%!*+$)'#*(**%(%#"")"+$!!$$(%$++(&%'&)'(&&!"&%*"*&'(#*%)&#($##")#(+++&)%$$()$##*!***'*#"("$'&))+#*+)%!(#!&*$%+#&%)#*%**%!"$*+*!%(*+%#$"%+!)*!+!)&!)#(+(&$+%*%'(((*(!$$#+!!'%(&#"*&*'%#!%##$%)"%+&('(((!"*$"')+)+$+%+&&!'"($(*&+#'#!"%!+%$%*!)+!+$+&+!&#$)$"(&*&&$))$*(%(&(##'!+*##%*$!$+'!#'+"("$#($#((!(%!*""!!**!()%#$%%$!'++$'!*'+)"+!"$$"&!((#*%+**!%&*+)*)*(!#!(('!)!&&!%$+)"*&%)"+)"((*'!&(&"*%"'''+*"'()()")#%!#$(&&"("$%''))!'+
@r3386
CNTNACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGNATGAACGGGAAAGAATCCAGCAATACATCANACGCCGCG
+
#$("$'&($"#)(++(*%*$++")*("!($**(*!!!!!&!$(*#!")$*#(*+"$&&&$'$!"*+'"#%'#")&")$()&$&!'"("!&(((#%!%##%""*''%'(*%)%
@r3387
CCAGACCTTACCTTCGATAACCAGAAGACCTNCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGNCCGTCATACACTTGCTCCTTTCAGTC
+
@@".,*D*A*3%=H9D'5)6EG.'E!@%7C+A0G3GF10A$5;%6$1&F@11@;;GC>D>6,=)>$%G1:G465!,#6#/?F#0<"B/12)3,64392C+10H6C!*6AC/-/!::=53%;94A<8'9/%+B/3&GD=)&8(/7:!:3:0ED%,D0D6:6%=F.:=(7%'5&4A=H".
@r3388
CCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGANANGGGCAATCAGTTCATCTTTCGTCATNGACTCCTCCACAGAGAAACTATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTNCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGNTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGC
+
-89*:'"!.1>8=)6D9>%:FB&,>.$&:(G155891CC86@>'%F"</$D8D8$E#<-AH'&?)1F#:%GH4@F(*&"A!'2+-=.C9C5'":!A!05(+>!-2!DC@G>08D!78D!-*?<<B1703)B':%#2")2*44($&>??-EE">3CA+?!"F:3)G)+4CC$A6:/;"1'@+G<A!.#6H-A6)$,87#*23&B$8>>!.CHD93+&1**7#22'F06+5+$"D&?9B*H.&:F3;/F7*=2B&3<)DGFH.H)9;4@F9%
@r3389
CGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTNATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTANTATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCGATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCNGATCGGAT
+
*=&;.E/@=0'1'$/1E+%F!()<E8</FG?B;954HFD@0B7!*7E+#5.@0+#F5247B@&:D<9)?==)3,'#9F/:2.1H#%=D?1D;%7$43)0?"!*1#")>0$'F!HE(BE#*F295/A0($5-C$>!/2GFF<(#2&?7G;9:>&3#<"4,'E":#GG))+3$4(&9+D,'G2H=DA7%/'3-G3E.G:9G('CE5;C+;D0(+$59CB?>5*"-4%.-H>D)B>D>9!2;"1'%;=&?3+.4GF8:C,/%*?47=@:$$G(9'%>3'.+"1+;8#5*0(2='B?1D2>=7!',#)F#23.1F4$5-'+<HH6B.15<4H3=".+:C#@422<&A#'%<9?(72/$&''6,;8D<A+.7.(6'D!:*5%02;D2D,0"(C/7<%9+1#=!H8A%5%%:+$F&0?GC&:5H,:!5%GDCF+,$C1#(!>=E<4
@r3390
CGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCTTCGGATAAGACGTNGACNTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACNGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGNTTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTAAGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAGAACAGAACTGCTGGAAACGNAGACCGTGGATCTC
+
D$;,0&8>(:2,&=#>$%H@G!)&/7<0D&E<(4E048!:G4BF@?5,<47DHE94DG>2<H(B0)/'G$2#/'8F&B;0D+0FD>"$8@D()-!:65E.B.'/07051H"HG18G5F,2%'1>1BF:>2)/1@A#@D0F&33>-B91B6&"-CF:7FBH@E>C,+!A;8+!$3-8.&CHG6.7%B2'+$&@2#H2;GG.3-%!2)G@EC1-0*$:BB3+;E3)$D#!23>?B:,F1)92=34$83#D=*+,7:)D%%$.<"1B"AE48A:B/9(#"9A3%&*-2$.)==*A$A?A!:)2$&,</3?)4;E#E=%14,'@)15#04F>(GA.2!3&;%(#9G/.6425<38AG?(.)><BE5;#$702*D.$&*;8%+#"?;":@.H<:+7*0/G1>=+?/%5*!H)),@>*&?D/F9B-)38687;:*%1.7658-
@r3391
AANNGNNCTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCTCCATGTACCGGGCGATGGTATTGAAATNTGCGATGATGACTATGCCGGTATCAGC
+
(#!!)"%+#+$)'$%%*%)%!((*(+%+!""%#&(''(**!(%%*#*%*+'$&$#+(%"*!#%$!++$*!)$(!'+&!"$'""*"$#'+&*#$&%+#$)!*)')&&**)$#&
@r3392
TTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATAGTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATAC
+
/7A0FG#03!)5A)03->'D8GH*%A8(%%/-=;)C';/(5#./0!E<,<1C"%,+@B)0"D-F.)"%)@,(2=D4"$:4E?EG5C+6"&A6/B+#@8:8D@#(@H*639",8+;5D8&5)0"-,#=/3E!2)@/$GH!2=>'9*EB)88</E424D1B7E+?@%F;A=7)?2A;"CE->@.<7HHGH$19<+8D6H@:4&1?441/6431DE!$'/"/C<7EC-$$*;"3%&*)';*<'D60&A:B67=913;-H<(D-/)$/.'>0#802EF@D!.5CHF-3("EF8*%2!=3B:3/?/AFD.D@">15BC=
@r3393
CTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGA
+
F39%B+B:$&H,;@A/:/1#F0?36!C'F=27-%@))C48+@7+0>FD#>H0="+G:6>2C&A"%"!=4+9&;">=-5;GG&F-E.=)7$;8=49<(4#6(%$%,<!-#E"H7D;/%>9F&$C?A,BCA8E@&;;/"*2=5%'D
@r3394
NGNNNAANCANCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATGTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACA
+
!%$#"*#!(&"%+#(%$!*&($#'"$+#"(&+*(&#&!(&##+!)&+$+%#%)")(#'%!*(*!&!%*"#%*+)*)*%"!#&+!+!+*$##$+(*)$*%+&"'+%
@r3395
NTATGAAGGATTATTCCCTGGTGGTTGACCGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTG
+
"D6)C?5:"F6#:>/*83D@>+A674*6.)673B!C;2"?A-#G9HA:E"%F99B*?"FG'9@0>EF*"H:0$9'B-9<3,D1H"4?#.B?(8BC?!GBE;9G&9D9*7E#6/-@1C65?387;
@r3396
AGAGCTNTCTTAANAGNCAAGTTGCTTGCTGTAGGCATCCCTCCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGTGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGTCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGNTAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTNCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATNATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATNTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGNCTTGTGCCTTTGCCGCGAGAATGGCGGNCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGNGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCAC
+
*&)%!##%"'("!#"('&((('+#%+'&)&!$%!()(+#+'&#""!!)(!)+)%%("$%(($$#&%'&)$%+'!#)*&"*)*'**&+"&"!+*+*#$$+$$+(+'%+)("#%$*+$''("*#)*+)()!*(%*+*%&'#"#$*''%+*#*%)"%+(&)"(&!*($""%)*'*#%'(*!&*'#+$!'"%&'(('(*"+%+$*#"#(!"!"+''%")(!&())%!+))!##$)++*&#%(+!!&#"*(##&)%!*)&$+!(!(&)!%&)"*!!(+!)%"!"*$#%+**"($+)*")&*"*$%'&#&*%%*'$##""&#*'#'$#$$#!(*'##!#!'"!*+%#$$'*#""#)(##%&++"&"('*$*(*"'%)++&*+($%$&%!'""$&&"'&!+(!)+)$"&%#*'!#")$'!)&#((*&$'&&*%&)""+!&$&%"))"%)"*)%'(%%')#*#*#&*((!$$+($(%"''"&#*+$#%+&+'*+*+"&)%!$%&+&)&!'+%#"*#%$*$#%$*"&+!$"*')*'%'%+#%!"("*#)!!+*&(#+'&"+*%&#&#+*!)(')")(+!)##$$$!#(*%&)"+((")%)+'+%+%*+#*(()!#!+$$!$&)+(+#(()$!$*)'#+#'#)'&!""(!#&'*'$''+"&)#!*'"$+')%)("'%*!*+!"+)!%("(&$+)
@r3397
TTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCT
+
2-796G@?,:2H$98&'(5%#4#9*2?$6/#%22<0E,>)((830:
@r3398
TTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTNAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATANATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCNCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATNTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTNGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGNAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCT
+
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
@r3399
AGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTANGACGTAATGAACCACNGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAA
+
A+?E3!)EGGB<--!0"G.%C;?9-5&1A?HC+3?<B2E$@,8&;"+:GE=%--A>DC&9DD-D1-7>6">-7+"H/!F;(4E-CD:+#>#%4!00)<)H@$+D&0@)&8',:A4+*2'<.(0)BHE5?!#@.?6=&@0"-DF;E8H@G!2E98B0#/.H7%51D+2(;:""C92E:.B?'';FC@A?!01*2,C$6#(B97+%DF'*;0B#0'<)-#=F$&7<=H!DD?-<3FG)*2'-A+<%0<"3D@':-G8/$10/H%;->)"$AA$*1<EA#&8#
@r3400
CCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGANGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGTGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGAC
+
/+&<4'D4;7(!"D1A!!2DE,4(B!*=6B<B7HD?0C0!(HA"'!4++#>(//><A7C=D6:;&?DE:F=3!D8$"113;.:9#(B%H-$0B17A*H!D;;1#+;?@)/),C?E=/A)0?56DH;&&=,C?B@5B&C-!)8C2>=1E))-'))%.18%7)0/CAA5"/'*;%6<-#!.
@r3401
TAAANAATCAACCCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACAGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCNAAAAGATTCGATACCGGCTTTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTNAATGCAAAGAAGATAACCGCTTCCGACCAAATCCACCTTACTGGAATCGATGGTGTCTCCGGTGTGAGAGAACACCAACAGGGGTGTTACCACNACCNCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAATCCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTC
+
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
@r3402
TACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTNCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGC
+
?C/@64F16/*7G<E;@;;A";%2C)G<*D1+2$31FAH;0<BD7(A>#!A7790(*<FGF>09<EF2(=?)B"C4'"F!'5E9&,?BE!<H-:@41/9656G%F3-*F;%<BD*&&)69D))B>E<;'>F3(F<EB;F7$4;H/,150)'C$G;2
@r3403
CCTGATGCAGGGGCAGGCTTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCA
+
A)!-"1>A'5=.*,G:2%97F16?-#-9-,+='#@G30@@(>:EFG-9"B.*@$=EBA:9.
@r3404
CAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCGTTTTTAAAGAAATATTCNATCAAGTGCGAAAAGATTTAGACTGTGAATT
+
A@/%%%!&@EA3"*#2*)"9#!!;$%E"924$A1=5/EFF<(;BE2/:0"C/A"A9?B7:A/-0H4DF0"4=-&0A9)7-HG"$H?)=+/2:+,,7F&00/!&8CD1,&,C34<@(!:H$/)6:,2"3$:<>?>0)3>*8=*%B'3D:*-7D!8$?'F.F9&35('',C>(@6?&7/BB(6=@=H-%"F:G0,!7&?9%D+<!(@BE%)4&15(@7);6:A8/$&>!-()B.&)7/7"#@08?&3"B,#**<A7GE,7A(!"#F0.1E)E#+(18>$@:,1?:%A#5D4615:26-$F264*>973!F#)3H4!(!"0E#B2-3?%&9B@/;'<;?8B<.(!@045.BD2('$"+@)';%<8/?2"="!
@r3405
ATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTNGGTGTTTATGCCTACTTTATCGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCNGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTAC
+
;88C'39894,&C7%07C'3-)#>(?,@BA#(?7'<;)7;>-*1CG+3HFA7+-DE+7?%A<#%A+-C$A71D9&'+3E=C?(;H@H2$,5*.4>2**HADFBG4DAB=/#B/?D1*.4$1?<@1>834-.5<((B87G<8.)G/3%A=G?HC.>;&A:60FD5(8$.@"E&9.<<7B;$F!+@-1D&@D!/353:D=?&(GB0;E+5H%G;&/*)3566+0A03'0>+50,:A>CB:99<(0=>%&-FB9,&<0=94)6A1+8"#E'@:,/C.@;"'H*F;8.'5&>2@H:2+F($3"D+2:"+>*,5:.<$%3B-361(0D#
@r3406
NCCAAGCTTGCAGAAACGACTTTTTTAAAGGACNGTTATCACATTCAAATTTTTTATGATAAACAATTCCATCCAATTGNTTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTCGCGTTATGCAGCTGACAGAGCCAAA
+
#&+$)'"!+&!!'!)+&'&&!(%*!!)))!"($"($'+!%#*"&#"#!+$*%'&"++#'(*'"&%!#*!$!$%!"%&+)+'&()#*'!#))!'*#%'#)"*%'!$%**$"(%'#'"##$"+'&())%(!(()$%&&"$'%$'*)"'&(%+$#%
@r3407
TGNNTNNNTCNNNGCNTNNGNGNNANGCNCNGNNCCNCNGTNCTNTCTNNNNNTNAANNTNNGAAGCATGNNNNACNTNNCACNNCNNGTGTNATNAGTNNCNNTNNTGNGNGNNGGAGNCNNTNNNNNACNTNTGAANNNTGNCNANGTNAGNNNNNGNTTNCTNNCAGNNNANTTNGACTAACNNNGCGGGNTNNNNNNANAGNCNANCTNCGCNTCCGGCGNANANTNANNTNNNNATATNNNNANNCNGNANNNAGGNAACCGGNNATGACGTANNATGGGNCAANNNTNNGTANNNACNTNTCANTNGANNNNNNNNNGTNGAGANCNNCNCNCAGNNNCCNCTNTCNGNCTNATGNANNTTACNCTTACTNGGNANNCNNCCGTAGTCNAGGNNNANNTANNNNNCNNATNNTNTNNNNCAGCCNGNNANAANACGANNTNNCNANNNAAANNNNNNNNNNNNNNNTTTGGNCNNNNNNNCTNANAGNNNNANGGGCNTNNTCNNNNNGTNTNACNAGCNCATGNAGCTCNANGANNNNNNNGNTTGNGNCNNTGTTNNNCNNTCACTNNNGNACTNATATGTNTCNNTANNCNNANNNAANNNCCTGNNGGCNNCNGNTNTANTNACANNNNNTTNTAGNNNNNNNAANAGNAANGNNNCNCNTATCTACNANNNNTNGANNNATGNATTNTNNTCNCNGNANNGTNNTATCGANGANGNCANGGNNNTNNCTNNNNTNTTANTNTNNGGNCNNCNANNNANTATCACGNGCTNANNNNNNTTNANNNNTTCNNACNANGGNCGAATNNNATGNNNNANNNNNNNNCNNGANNGNNNNTTANGNCNANNTCCGCNNNNGNGNCAAATCTTATNNCNAGGCCNNGTANNTTNNGGNGCATNNNAGANNGTNNGGTGGANNTNNNNNGTAANNACTTNTCGTTNANNGAGNAGNGCCCNCNNTNNNAGNCAATGTCATCNGAGCNNATNCNNNNNNNGANTTNNGNNNANNCNCGTNNGGNNNNNANGNCTNATNTCCGTTGCAANAGCTTCGNNTNAAACCCNANTTTNANNAGANNGCANNNTGCANTNNNTACTGNAGCANANCNTGNTNNTTNGNNGNCTGNNNNAANTNGANNGANCNAGTTNANAATNNNAAGTGGGTACCTTNNCTGGNNNGNAACANTTTCANNNNATGNCNNTCGTCTTNTTGATNNNNNNAAAGNANNCNNNNGNCNNGAAAGNNNTACNCNNGATTNTTANNTNGGNNTCNGGCNNGNNNNCAGNAATNATNTGNAANNANGCCNA
+
$$""#!!$!!!!!#$!##!!"!#$"$$"$#""#$##!!!!!!$#"#!"$!!#$#!!!#$$#$""$"###"!$$!$#!$"#$!"!##"!#""$"""!"!$!"$#!#!""$!##$$#$$$!"!!""$!#"#$$$$!$"$$#!$""##!"###!#""##"!$""!"$$#"##"#$#$"$!"#$$#$"$"#$##!!$!$""#""#""!"!!#$$$"!"!$#"#"#"#""#!!$$"#!"$"#$#"$"!!$"$#"#!$!#"$!"#$#$$#$!#!!"#"#""#"$##$"$!#!"$!!"!$$"!$#"!!#!##!""####$#$"#!#!!!!"$#$$!"!$"$""##$#$!!$$$!$$#$""$"!#!$"#"#"##!$!!!"#$"#!$$$#""##!""$#""$""#!##!!#!!"#!!!#"##!#"!!$#$$#!$#"!!#$#!"$!"$##$#$$"$"!"!#"!##$"#"$""!#!!!"$"!$##"!"#!#$"#"!$!###!$"#!$#$"$#$!!"#!$##"$#""#$#!"##!""$"$""!$"!"#"#!#"#!$#!#!#"""!$#"$#"#!$$$!"!!!$$"###!!"#!!!!!$!$##$$$"$"!#"$"!!""#"!#"""!!$"$#$"##$"!!!!""!"$$"#$!"!!#$#"##!##"!"$$$#$$!!$!$""$$$$!#$#!$#"!$##$"#"##!$!"$!!!!$$$#!#$"#!!!!"$$!!!#!#!!##!$#!$$#"!""#$$!""#!"#!"$$""$$"$"$$!!#""!#"!$!#!!#$$!$#!!$""$#!$!#""##"#"#"$$!$$#$!$$$$!$"$$!$!"!$!!!!$###"$"$"!!"#""""#"!$!#"$"""###""$$!"!#"$"$"$"!#$"#"$$!!$!!##!##!$#$"!$"$#!$$$#$!"$!#!#""#!"$!!$""!"$!!""#""!$#"""#$"$!""$!$#!$#""#!$$""#!"$"##"!#$!!!##""$!#!$!$##!!#$!"#!$!!$$!$!"""""#!#"#$""$$!"$##"$"!$"""""#$$$!#""##"$#$$"$"!$#"$!#$#"#!#$!!!##$#$$"#"""#$#!!$$#"#"$$$"#""!!#"!!"##$#$#$$"#$###""$$"##!!!$$#$!$!$$!$#"#!#!"###$#"#!$$$#$$"!$$##"#!$"""!#!#!##!$$#$"$!$#"$"""$$!$"#$#""!!$#""#""!"$!!"$$"$$$$###!$$!"$$""!"$$#$!#$!!#!$#"!"!"$$#$$#$"!!$#$"$!$$#!$$#"#"#$!$"#$$#$"!"!"!!##""$#!!$!#
@r3408
CCNTTTTGACTGNNGCTNCNGANTNAGCACGCGCCGCCAGCACGTCCGCNGGACAGGCTGCATCGTCNGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTAAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGATCGCCTCTGCCGCGG
+
$*#(($*($*))#'#$!!*$($##$*+!"*&+#%#+&&"+"+"%$&(%&!(&%%'*%'*(&"%!*"(#%')(*"'!++&&"&$'%+"+"!"&(+$!+$&+!)&"*&$*'$)*"'")%%#"+%*&+$'!%$#%*'(%&()'!((%$'#!)$&++*)%)%(#'*'&"$#+)$"*&"(*#$!'#'!$#&'*"(&)+%('$&#')'+#"'&")')&++#)!&#%')$%$)!(+!+('%**%)$!"+&'$$)&+&#&""*(**!#)!+$*"$%()&(&+'&*&#)!&#*#&)%&$#&+$&")""%*&)+*'#%#!++)&&&#$*$)(+)*!#)!)%+#'!)")$"&**'$)*(%'$')('+#('%"%+!(%'"$&+)"+'&#(&+'%$*"'$!!#'!&(&&(&&#)%*&+""$&*$$!*!&'*+''$"#)&$")''*"'#)*"$&&#"$*'##+!*(#+&%)&)
@r3409
NGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAANGAANAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGACTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATT
+
"GEDA1%E=3142(96B@D4(2!#$#,")4CB;.?F340#&-F;*F=+'%#%0$G'#=./;+8)A*>&'*+<H&-HC0HE)GB;F?,0?2<!<$F*A%+<#;"((F0%2%:3"&?-2F*8)".-:1-8*/&;6">3=!4<7,)7@"7$?4=707A!'1*6!.'G/,%/9:D(=E#3?C4)B>/E*5*B3*0D39:#=)(F?1!:!'<)#&@8-B"$3&)2&3D(=G=,)#50-'@D9!5+$1,@6=:'60++B)/%9B7!3G#E;8=H2#B*F2%;7'5G%'+856+D/30)B=C#08+)7;)53/+%*/HC!E)0>:"C9)/&E.!(3$=FD#C@-3<30:8?7C
@r3410
ATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCAACACC
+
#5#=?$)D:?6*(@!/!%)FA95+035<#GC68!G+)!/52F<"D(:&+3+F14++?9&/*F8A?/H")F,*A?8$.?)"35**6%"/$;''+"!(G<@B<"B,8+
@r3411
CGCATGGCAGAACACNTNCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCNCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCANCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTA
+
,;CC?/04*+)&8+",D?>%8DHG*-8ADFG:H:@A/'2!"+$<=8:#?&<E<$(3A%A0BDF-30+'*<2#'-38,<5+A?BD:'/!>)'"$:C;(!2:0=/41'8D:=<?BB!C16-D)$%<BB'%/#B3*1.=:&E#<60*"F98#<9%*H././<C#9*0!+$;!@64%?%/B3".2&&A/C6,6)9;+DD1CE<(@;*&0)/A/">/78(31:<C=+F'2#.9G'.9=E'"'9'-2/%?CDC#:C006+)@1<<820*38+&-/9F.(G%)C!<0!2$:0FC*<02.2H/3;5<79':B/(8/8":*:>(*!HC?EF?2A$5G%92H0/D?H,.??E54<#C=..HADA.>E60*4(6$3-41!B)<1.04%#H9?3,6C$:7)D80!
@r3412
GTGGTAAAACAACAANTTTGAATGGAATGATTGGTGCAATCACCAACCCA
+
)1#C-><2;E4,>><.1><1&A,%;,F!,)G1/;8"+/DC0(E.%$"<?*
@r3413
AGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAG
+
==.F;6+)$?+4#!)5A#"DB00>//).0>=!=*%:H34'C8D>+'81@=6C"$!C6-A;'3G=B'@3?&<,@+2=/+%9B1@"-4-E"D88E)0;%"7,
@r3414
GTGANNATAATNNTGNACGNTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTNCATGAGACTTATAAACCTTCATGGAATATTTGTATGNCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACANGACACCGGANCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCANTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCA
+
)($"%*(''$)$%&&%$%*"(+')(&"+%&&''"+%*!$*+('$&'&)"#%%*+&)"!)++!)(!)#&#'!%+"+(&"*!')#+!#(#"*%'$&&*!$""($$)$)&!!'$+#"(+%$'$'%!'#'*+#()!$$$%'$!$+'+'+")&&&(++(#*'#+)&"+%)"+$*#*#$%!("+(#($)!$$!&+$!"()&*(""$%)%"'''$!"(#()%(&$'**+*%"%)+("+&*###*)++"#$!++*&+$##('''"(!
@r3415
ATANNNNTGATGNNTCCAATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCNATCTACTCTCATACAACCAATAAATGCNGAAATGAATTCTAAGCGGAGATNGCCTAGCGATTTTAAACTATTGCTGGCAGCN
+
'#&&"'"''*((%!)+&*(&')*%()'(&&$%(&)"!'$'#!!%"#(!&%)#"'*(*#'!$&&%!+$$&*))"*$"#"**%+&%!()"(#"(+$'%(+)(!(%++*!!!'%")&%!#$%$)*&$()'$#!%))#(##)+('('+$)#+$!&#)!*#+#+#('&$*
@r3416
GCACCGGTCGCCACCGCCAGCGAGTTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTNAACATGGGGATCATCCCGCCNAAGGAGTCC
+
537E-=691H<+?6"36)$A)((A(%6:8/'37D%G?/,6#<7(HHG./D34:2G(.:-C5,*2?4C.))41952D1-0F,7E).98D!!H&<>%<.F?
@r3417
CTTGAGGTTGCATGTAATTCCATGACCGCACCAACAGGCTCCAACNTTCCTGACGGAATGTTCATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGNTGATTTCTGCATAGCCAGACTTGNGGGTGATGAGTTTACCTTCAAGAAGCTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCNCTAAACCAACAGTACCCAATGATCCCATGCAATGAGAGTTGNTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTNACCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTNTCACTNCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATATACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAANGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATNTTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGNGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTAAGCATATGCATTTCNTCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTAT
+
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
@r3418
NTCNNNANGNNTNNGNNNTNNNTNTNNTNNNTNNTNNNNTGNTNCNNTTNCAGCTTNNNNGNNNNCNNTNCTTAG
+
$!$!!!$!""$#!"##"$""#"##"###!#!#!"$$"!!$"!#$##"$!#$$#$$$#!!!$#"!!$"!"#$""#"
@r3419
CCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATNTTTTCAAAGGCAAGAAAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTNGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAATGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAANCATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTG
+
47/E!.0F8#<H;E7+1>76*F/".;'4D3(1,C<D+&@E'@>$E>4/!4,AH6EB50349,-9>1=C$-//1G4/6GG-.=BA?@)#9&&"A(D3D,0/,(?H5>B=B/GF@=E)&1/(2@$&0.@%@HF@"+F3$4FA$"892;3=+4)E@::'0;"D5F!>(4(*<&7H.6<9'$$59@43/'+:0.2D2).;:/,G8+/5G=4@!#&A#2(>4@#+F,6((5/907)('$EBD4&!@%''$F>&3'#49D=)417FA)H9:2C5FF-A6(G3-18EA&E7,+61D%9%;9$3<=E9/<<A0>'!F39%%01"4#1H4+,>&DF4!9<'.1493G2*;(B4AF@94?,..'&3AD%-FE3H8?F$A@#.=:&84C*>0,=)G,#(9$4&''G6H+=,9,'=H;$D)->*;0$=2)5&5<"?(*G'.>.
@r3420
CTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCG
+
38(#D7+>."BC7#@*D$0@,.B'80#%?/A'3A/F.A&.#'@H)8$>6:3>%B/D$?<+-0,#-8,)>H<<<ED&$3-%D'2+H+E&?6"8D:$A3D.>>@1;=,E(D??4B<D'B49*G/E*62'*14*$C'F<369+(%(D&9A'005-"<=.8.E-4A)291F!3F%;0G7),?H<@?=#42-%4=-H<6%1A)*('4E):6?FH5=$/3=3(G&/814
@r3421
GCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGNTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCC
+
=H)71H:*<;@/"A#E>92&%D7=<(-'C++1#)&?>@-7C2/'-G($$)4E%@:,)8*"40>)H6+F=)3E1,0.$@,4)!@*8>*B"09A5E;CH/62'&5-F*EG,)H&1$AC$D4&AC#5;.2!:.@=)#$@FA@33E2:?E*$8'26@+68<$'$AE:26".FH5'-=:1EH2+F.'&"E'D<:""%>HA-<>-:8;,H-,<G;63A"&72%E,25*16F
@r3422
AGGGNAGCACNNCNACCAANTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGGTACAGGCTCCTTTTTTATTATTCCCATTCACCCACAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCANAAATAGAAGAATTACAGCGCAACACAGCAATAAANGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTNATGTTTTTATTTAAANTACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAGAAAGCAGCTGGCNGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACNGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTNATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGNAGAACTGCGNCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAG
+
"#&)!##')(&!$#($"#!%+'*!*!*#')+##+%%(!!$&*(!"!*$""&!)"*)#)'**+'+&*!%!!#!+$*("$)$%$!+&&$#(#!)'!%&#%$+*$'""'$)%$')!$%#&$%*!"+"'+"(*&!##*)'(!!(#'')(%'+$$#&+('%'#$&""&$&)!!'+$)%+)*"&*'%$+(&%"%#)$!)&!(&*%%)"*(&'(!(+#*%"%$&%''+*#*!*!*"''+$*$""*'+!'%"'!&&)$#)+%%+$($!+')&*$"!'!)#)#(*$*"*&'%%'&)*++#+&#'##$)#)%%$"*%!&'(!'+'!"(%#%'!*#)"&%!'#%*''+)&&#"$**$%+'#$$#"$!!&+%)''#*#(###((*##%("*)&%#!$!%'&!"*"**(*%'#+$#$$%)$*!'(%%)&#$%*$!+#'*+!'+**&()#(*!('#"*'##((!#"+""')#"&'#!+)*""*+$)"+'&#+$$%%("%$!%%*"$$()#)"!&!$*)*%))#+#+&)"#$(*%"&%!&&))*#!()*!&***&)""!%$+**''!+#(!&"+!+#%*('!!+$#&++%(#*#'$+&"("*"#&"*%'*'''(!)#+'''*)%)%&''&'"*%*!%)##**')('*"!(!$()"&!('!)%*'!&+&&('&###*'*$%&&
@r3423
ATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGGCCTTCTAATCCTATCTGACCANTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTNAATATCCGGACGGATAATATTTATTGCTTCTGTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGNAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGANAAGTTTTCANCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTNTCANACAACCAATAAATGCTGAAA
+
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
@r3424
ATTGATTCNGCANCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTCTGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAANCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGT
+
+'%%)#*$)"*!"'&+%##()&*%)'(*)!#++)$&$*(#%%#)()+#('))!('!$!)%(*##'$%*)(*&%%)&%%"'$"(!!(('(*%"%#$'$*%%)!'**)&'$*))(*((&'!+(%%$&)&)%()$))#!%#+"('%)'"#!!+#'#*+'%*((%'))$%#!+'%+#%*$)""$**'"'!$%!('!*%)%!+*'%''"'(()$*$'"+"%(*%*#%#&+#&$*$"*(#)#+)$!+!$*$)+#'%%*'!!!&!"#*%"$+$&'*)&#&!##(*%
@r3425
CNTCTGACCAGAAATTANTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGNTGCTTTCCAGTCGTAATCAATGATGTATNTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACGTTGCTCCGTGTATTCAATCGTTGGAATGAACACAG
+
!"*$#)+"($*'("%#+))!+$!#'#*$++$""*(+'&"&&!#*!+'#"'&))##%'"(#'")'#!%+&&$&#)')$'&!%')#%((!$)&'*$%))%%#!*%!)#+&*)"%#'!%&&!)"%%##()$')('&')+'$)"'+!%%&##'%%')#)$#&$&#(&')+)"'$%##+*$&##()+('+)%!&'##'!("$("'!)*"(#$'&'&"!!#$")$'!#!#(&"))!!$")((*'&*+$&%!!((+"''#"'"%
@r3426
GAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTANATGTTTTGTACAGAGAGGGCATGTATCGTTTCCACCGTACTCGTGATAA
+
.D?F#.9/1A&%.03&1F2HHB&(H1C5.DH"%59!E&G3>3+CG=H4<<G+73.,C#+B1))9;5=,,+6BF9$&15+E!?AE+2)656)
@r3427
TNGGTGCTTANCATNNGTNNGNNTTGTAAANNNCNNNGNGGCATNNTNNTNNNGACNNCGNNGGCCTNGGCNCTANNNCNGNANNNGACNGTNNANTGNNNACNGNTNANNANCANGNANNGTTNNNNTGNCNANNTCTGNNNNGTNAGNNGTGGNNCNNNNTTNGNTACGNNNNNTCNNNNNNCCCCNTACNNTNNGGGNGNNNNTNNGNCNTTTTCCTCCNNNCGNNGNANNANNTANNCANNNCNGAGNNGTANNNANANANAGNGNTNCGAC
+
!!$$"!#$"!$"#$#"#"!##"#"#""$!"!"!"!###!$""$##!#$#$#$"$$$!$!!"$#$"##!##!$$""!$###"!!$"""#!##"!#"!#$#""#!!#!!!!#""##$!#!!"!""$"!!$#!!##"!!#$!$"!!#"$!##!"$!"$"####"#$#!#$##"!##$!$#"##$#""##"$$!#""##""#$!!"#"!"##$##!"$$"$#$!$#!####"""!#!!$$!###"#"!$$!#"#$!$#$##"#!!#"#!"#"$!#"#$$$
@r3428
NTNCGGACTGATGAGGTGCGGCANCTGCGGCGTGGAGACACGCTGACCATCGGTGATGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATTTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCNCCN
+
!'%+$""#"$)*"#**%#()("'%&($$*%+#($#('+)"++&"%%%)%&$&"+($%&%(('%+"#(##**&'()+%$+*&$$$#)%%#($!$*#'+$&'&"'*%*$)%#'$+'####*%&$()&+&'%*"$*")+%(#&&&!")#(#!'""(*#*"#!$!$$')')+)%&+!$'%'+#"*)*"#%$)&!(##()(+&&&$%%'%#%#!%(#$'*(*+!*'**'&&(%"%("))'+)&#"++*(''%+*(#%*%"'"(&'$')*##'!&'#+&('
@r3429
TTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTCAGTGGCCTGCTGTCCCTGTTATGG
+
*;*$*)2@23GC7/>EC0&7D1"@5!#$86A(,!C#+.'9*?#%?2(C8#$-5>.:8-(,H*6"
@r3430
ATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTG
+
48<D361#0,.:A%>::.2,%+-!9/=-63/?D:/HD&)05@$0
@r3431
AGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGGGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCNTTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCNGAGTCAGGCGTCATTTTTNTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGNGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTNATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGNCCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAG
+
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
@r3432
TTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCNTTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACNTCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTATATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCANTTATGGTGAACAGTCAACCACCNGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATA
+
7.),4?(?FF1CB$13*?!&C5-.A0A,)$.DD)%<G9#F;C;@*?0%DFDF94H$;&.)!=:>5&??41'$CGH'G&E@%=F=:C<>$/8#=418!((E"#($@,H9"!76EAH85(FFH/!:!B)&'D@'9'3H:1>)&<C90(G/5FB'(&:$<%278%<1DBG$.+F<%/"%&8$,F4>&C95G/A*5=G$G;#16/:&";821&6&3C'(!$>%9=(!#+8.A!37240$':D"":5GF5B8'?5,:,/47C"+DFDA-<#E/+<3,)+(/G;"B>C1"!C3*2'$%'0&'!-9G&1+*A<F:++H,.0B-'9%>7448$AFC+#0"%8<8.5"9+$("D#8FF)"18$3/FF7()B+$"4;FB?!'4*&2A:8&;H:7G.,3+-<')11=*61?1G7*E5%)B&B!4#23E"%63/)H-.!1A.FC=H%*A@993
@r3433
NCCGTGTGCGTGACATAAAACCGGTATGGGNGCTNGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTNGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGNCCGGACAGGCTCCACCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACNCTGATTTACAGCGGCAGCCNTAAGGTGGATGACAACCCCTACAGCCATCTTCCGGATGACGTCCNGGAGACACTGCAGTCCCGGATGGANGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCNATGCGATCACCGTCATGCGTGATG
+
'+*$*&*'!$#+#%*#$#+&#+)&%%*#$!"&()&"!%%")'#+)+''*)()"%!#%&&"%&&*"*!+'*'#"%*(&))%"**$(!"**%$#'(&***"%)#)*)$!'%"&*%)#&"&##%'!)#&+%#'"*($**!$)"&"+!+$'(%#%+'""(#$!$!#($&*((&*+"$$**&)*()!*$$#+!($('$#+%!$(*%)*#+*$%("%()&)!#''#)+(#()*"%)()%"&)($!##"**(+$##&+#%%($*'+!)+''#$**!()#&$#!"#&&$((%%&$!"(*#'"&)*(+#("#"#&'"#"'(&!!"$)'#'*)*$$%'*(#'%&*%#&(*'*($"!))()%'$!*+%"&&)%+)))"#%*&'$!!#+)!*&$')(!*'%&$'*)))$+(!#)%$$%+"%+%+!#$##+$#$"**!*+%&$"*##')%&!"&
@r3434
GCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGNTTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCNATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCNGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCCCGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACTATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCA
+
)*>2/D-!1E+633@D<8,&C-C5D703BB+@5/;7:?!77<-H*<:F4'E4-F*(6F;3>B485<$1F2??#*"7+!,'(F>02&B320,C5>)F"=1?'GE4"#6*;8//A";,*>@'$>D>FH"B?>..>(9,&".9C(A$2?+#.,((624%&(%'#E;*7"-<C>+E79%;&@3CC"D/52(,C#8@G2(=-!>4C91?E*4-E$-,8(%%5B8+:D+>+-32//8'?3F243B>0(%A0H&BH&$@AG-*?/13G1A(!5#"7054++1+90@,2.C?*:H>26>2E3";'<HB.(GDF=0HD5#61;7EA.5=$=659"#>%CC;$#'E91*?B76#B#FBD'"@:;1;989.EGB>:8F490=-,;F,B3';268+G8D6673B6#F(:;$:,0FH-H.*G<A<F
@r3435
CCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCACAGNAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACAGGTGGTCGTGTNCTGGCGGTGAACAGCCAGACCC
+
#E5,73&+5("#123D:F+?F"0;C?DB>G1'-?8#E<!$7F&+BDG=<F(&/-=58;A3+D3H3-<9--+0?3)B*F9&6+F<:4H'C':/,*9*.1"4-!H(!CE;8%16A,$6#(5;4@>;$?C5B406<!'C70A$"H2+!?3'E8H2CF,0,G*E/F";4<57(C:>!
@r3436
CACGTCGGNANTCTTTGNNGGCGGCATACGCATGGCGGCTTTATA
+
)('%(#*%!'"$*)"(%!&""%#+!!#&$"'$($"(%%'*"%"($
@r3437
ACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCGTCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGG
+
22/C30@;&DG.E%CCB;F-F4#G8B&!1(/3%@%A+9D;1A1HA<D$:$A2.<?8+<(:C-0D115:D:B+3>0"('8379=#3@HE+.!6*5!$>2%9>'H3'(G.B3.H,:1G5D!:H',"$6:1'6A,:17=(9&73CE%4:;5=HD?%45(>!&-4F2@<@A1(.!+(5)E)64."9B09CFHG/DG(8A6G#96?E5:A0
@r3438
GAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAANCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCTAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTANCATTGATTCAGGTACAGGGATAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTNCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGNTGGCTGCTATGGGGATGGCNCAATCACAAGCCGGATTCGGTATGGCTGCATTCNGCGGTAAGCACGAACTCAGCCAGAACGACAANCAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATA
+
7C;'<'*+/)B8=/C1+1E/;AH:,A+(/G!A65,F$=C:--7#G<(@:)C.$&0$<B(>)!BA,;8)32'03+0/<6(8;'=;9<(.0+!2-6EA%6##E%#7:6D+1/2H5!7CABB$C72-./=F42==#5622C&1A4C7F-H6BGH0!+:1$/F6;%8=D0F=:AC0-217G=A4"*='&2BD@'9#4#C)*?2(4*#:;<#88-%>.;;)*/0>("G!)""8,+@56-'*-3#:#1,4*7"@GA<@.=-E,+='G9#20(4/HE88&4%E,099;9@;($&6.&0!F!8G:10<'0-D&5H'/@41%9;!A!&,'5H,ED#*'C574F>C:4)E/(CH:$+16!$68.*,.9>$15!!-'0*%/,.=48?78'C5FG*>)E'.+C2E?97"&2%0%54+4?C&'#B59#7EHD2'6%
@r3439
TGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAA
+
9636)2-;.<.G;28:?-:6<0D,7!<:H:6);)DF0D)B%:%,%+*G:G'D6@?,H')/=A3(+9$B8-B,@G4;:+F*64&)E!5CE0
@r3440
TCCTCNGGCCTTTTCCCTGACACCGGACGGAAAGCTGAACGCTAAAAATNCGGATATCAGTGGCAGTGTGAATGNGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTATGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCTGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCCGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAG
+
?<F@E0/"(.E$0)=1>?G-D/>8'@>B*:)<.*C2.86<B!0FB46-71"E5)-+G1#>B)'#<.:+%'0+79E)5+%;F(796=0G+.0A<D/%*5-9?:4D!:"D3#<">G@28:7&97;$4F852*0>&51E#8D219>!('FC7(D#<6*%%*G:(0:0FD-$<B,7?0.B0H<:8$,#()A<333E>H3BC-@1$0887@=/C53+DG>&@*0=4$C:G#*-/.+9=.=&@E?*:9'-$;#,@%6/E)<8+95?@/7+-"E>7D;9!B
@r3441
CCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACNACATGAACTGCAGTGCAGNTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCNCCATC
+
F@'3-AF,!$D4CC/7BHC&@A:0GF)$;;.7(94>-"03F!()(;",G(:AG?1FBD3@7@EE.5>!3H)G">7%-B=.38<!6$"A*<;)4AE6/&6.A!@*.F,E%)!@.3-'HB=A6%DG;
@r3442
GTGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATAT
+
9.4.'AG1?=2<-E#)-H.B:E!,35*>B+'C7-DB(H!+6-<'A:>CA</++B-':"C(GA"#8;#4&A"92H+*/0>)1?>41B4.*#B-=B*5!.9+(*3(&1$"HC$B9E!!;GF9"/,'<(6F@35!$D='&;B;5"5DD-"2;6!3F=6
@r3443
CGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTNAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCA
+
4!<6$19G3$'16).%B%;;H/>A@6=//9.B'>1HBD;91<-(E-/;>8!H>,-!'=5.B1!,=.1F?9:+?A)(FGG-,D>%B3??90(B56H:5+5'/9&>;H=*??;.D<;*D=*'0G3DA*G3.;6)CA?;$5"F,..*>01"#DB,2%@2.@.!;@+&/#3%'D-)>&G&=F:+A!(34:576:9$?9A)2:G</C<:%:,A@1G4$*-(";G)AE=$%2<>H:>*%/).5=;39=#.*E4$)4.);DFD<@0A3C-)*#0:<<5&1D#=7.+/4CB>&0C@$*2*1<C8H>-(*)-%!9(:&=;80D-,3882'=#-3('+<3<GGDG80(B%9G.D!+(CD5+7"36F.5%
@r3444
AATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTNCTGCTGANGTGTCATTGAACAAGTCCCATGTCGGCAAGCNTAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATT
+
<*117+:4,,-%-4$"=%B!)5-E$@E:9E&:?=)A%1$155"'-,;(8D(!=-E4E1*D6%=8,@7%$+>=4E/'!!53C#%8E!)0?!8C"),B"<H:B8@?AE<!;;=78'HB#%<<=1H-5!"B!&-C>*<F'4E97E94G5++>":+6$)(A.!%+@1/C=E!=2+69A,$5%,#!6>G8<!"(8BGC.H)<"1:>&(;74E)EBC,//7(&158FECB5(,/9#1==",.0D71/E-E&!A4<7#!B.?=H<7)&$F<BD*380F%0B979B+/3B+6'7/$,!C%+'9>F?D#5?+3,5<5;G/-$B/;:2"B;4++-)##@60G5@/:$A"G
@r3445
CGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGC
+
%#4-:#;,6'C*9AB$<?"4>B#E9*DB6.!>"15FD6H:%,(>FG64C
@r3446
ANTGCAGGGTGAAACCATTCCCGGCNTTCATCGTTTTTACTTCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAACCTCGCTCGANGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTNCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGANGGTATTTGCAGCTNTCGCAGATTATGTCGGTGATANTTCGTCGCTGTCTCGNCACACGTCCTACTTTTCCTGCGGTAGTGGGAACACCCCTGTTNGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGNTTATCTTCTTTGCATTCACNGCACCGATAACATCGNATCATGCAGCTTCCCTCCCGAAGTCNAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGNGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACAACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAN
+
!"'+!#($!""%*+$)"&+'**&%!!)(%&""+"'$(""*#$&!+&'%'(##**&+*'())")'%))$&$"&"%$&)*&'$(")&&+*!#!)*!)#++)'&#+#)%!&($()('((##))##+*%&*"%"+*"''&(!%(*&++#$+))%(*"+!&$("&"$#*!$($'%)%"$(%&!'!(()*&)%*)"%'$"&%*&'+$++#$$&'((("*'$)+''+)**!"'%)#+$#$$&()'+&''#(()!&()+!"'&'#"!$)+'"*'%%"""+"!)+$)%%%'*+!($"!+#)%(&)%&#!''+'$%*%"+(&!#''&))*("%$)"*+#!(+!&%''%"&$!((*%((&)*!#$$+(&$+)#+*)%))!*($+'$+$+'!'$#(&'!(++%#)()*)"*#!+$"!*!+$'#)%+$!$%$%!***)")$!!"')#'%"('!(""&**'+)%'(%*!))+(!+*&!")'%&$!)%(%#*%*('**!#+('&&'#'")'()+$("&"!$!+")'#$#+$+&"+((&()+++#*(*++'"#)&$*%)'!'')'%$%#%!%%+"$%$("+$'"$"'*"+#)#&#)(*"+("!%+$$"!&($$!*"%%")&)()'""*%'%"#%#*&%++#&$'#+%$*)#+(##*("+&")'%'$!!%)+%*)!+)+*''!(!&&&&'!+)!"%%)*#$%'$&&(!$*))+'(&%'$("#!$%%)")$)''&+!"#%*"*'!+%*%(&+%)#$(%!"#)"%%#%&+)'""+'*#%%$")#)&&'!%%(#*)'"!!*!%$+'!((&#)*'&$%"'&!$)*)"+''!%*&'#$(&"&''+)*+$#%)"!!(&#*$&)!+$
@r3447
TTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTNAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTNAGTGCGTCANGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTNCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGNCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCNTTTCTCGTNGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTA
+
4+D:.<;4'%0+3%8GF"1-+)+8"@A;?H<<A=+31H!.4&9"%.&34,!D(A2$)B0+9%;EDFBB9D$H(=2$'G/AH>5CA*H'9!F?8)(6)?G:E6#8."*-39/'/(7*7!><.;?,:*2.0F::<36<F()(/#-/171HF!9/1B17=AF)6;=8+!"=!HE46=E>%)"55<#?#=B(.9+"E,?9B/5*##A:7A:06!F+*<:-2<9<.?($H',BFG'-(,/%B+<480D&G<)H1$B#(H5;DD=$/9#"<4E<2&DD!14)"/1EA-+%0A%237F%:E1G)9$6/<#>8D0E6D06F=""72AB//+A?0182"&$-*227"9D#3$G,FB'2=/-$'%>:!9'/3AF-65:E>+%3+G<7G.>>F1:>>(HF.(!C@C1;>H7+&:<+5>6'8.@D46DF:)&($57-A3)=))-4;5H7%HG7=%(/2$=4A)5C-;C!<$<#?46B8@/#";:5B-C/!+"FG6>)F*2E((+1@$'G"6
@r3448
CCNNGAGGCNNGCTNACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTNTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCANAAAAGGTCTNGGGCAGGCCGTTNAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCNGCGATATCGCAGTCGGCGTCACAGGTTNCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAA
+
%$!#$'()'%!(*%#+)'#%+'&&)'&+&!$+&$''('('*#)'$*)!(+&&(!*#"+'+)+"")'"")(+#*%#%+"'&&+&+'!+$&#$+&'$*"$'&%*(&()('#!&&&+'((($'$%++"$$'*+%*+("(&$)$(&#*(#$*')*)!%%!"%!#!'""#!)*)&'(!*$"!%*&*"*+&$!''*#)'#*##('#*'')'"$#&%%+(%'$*$#()*%"&&&*+$!)+#"&)+')$#$+'!")**(!)+*)#%)#&*"%$!%&($%)&)($+&"+%'"+*!)$*"%)''$*$%%**"%())&
@r3449
GANNTCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGGATGNTGCGTGTTGAGNTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGNAAACACTGACTGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTNGGAAATCGACCTGACAGAGGTCGGTGGAGTACGTTATTNTTTCTGTACTGAGCACAAAGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCANGCTGACGNTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGC
+
)&!!#+*&!"*%+#!)'##$*$&&$#'%+"")&"#(%'%''(!&+"'(")%*##+'*#*&(**%*"+*%+&%$)&%*(%'$(!#"#&&+("$"+)+*%!#+(&)$#!"+**%&)*%#'$"+#!'$!'*$&&+&&$)')'((*+!*!$'!)&")(+'+()"()%!&*%#*!#!!$#()($$()&**)*&!&*(+"%"%%!$!#)*+($'&#&"%'##!()&*'&!("*%!"$*'$+(#+)#)'""%&&+#&")'"%*'("***#&(*$!!$$%$#%*%**!$&$'%""&)((%+!+$"+%%$())!%$%!(*$)*!&)''")#)$(%&)")(%+$"&+!#(""&+)"&()*++$%!'+"%#$!'("##))*%#(*&+#$*&#'#!#!(+""$*#'%!$)+!+$*++&("()+&)%'%"$)$"!$"'!'+$$!'$%!++(*&%+)"!*&*()!**%(
@r3450
ANNGCGGCCTTAANACCTCATTTCTTAGAGGNNTATCTCCTNNTGAAATTCATGGANAGTTCGCTCGTGTGTTAAATGGTTTGCCAGAATTGTCNGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAGCTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAAAGGAATGATTGGTGCAACCACCAACCCAGAAAACNATGAATATTTTTNCTCTGAAAATAATCGACTTATCGAGCCAAGAATCCCAAATGGATATTTTCGATCGCTTGNTTCAGTTTCGTTTAGTGCANTTGCTCCTTTTACTCCTCCTAAAGAACAACCNGACCCAGCAAAAGGTACACA
+
'!"'&*$)$&)%)"#$$**$"*!$(#&&#('$$&*!'*%%'%!$(&*+!#+)#)&#%##+"&($"%&"'&"'+'&+(*&#(#&'$%+!"%$))%!&))'('"&)'$'')#!!+($+&!++(&*('"!%'")%*'$)"#*%(+$""+&!!'+'++&")+&()#%+"%$$&!*%&&"+"!#!!+)*)$)%&$(%!!)+#)&('&$'!*(+&%*%+!(*!!$&"#!!+!!+'(+)&)*&')*+$')!&$*'+%)+(+*!'%)+*#%'$$*)"#"%"%%!(*#*"(")+#$$*$#(!!)")"$&#(+(#&)#*#(+'(!#$$#!'&)*("))("")"%%$+&#+$(%%*#&+"#&&%)!)(&$'%!##$$"))'+$$)!!('+++#*'#%!!""+%(!!!+!$"!!%"&'!!*&*!'#''"#$!%
@r3451
ANGNNATGNNGNAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGA
+
#$(!"%)$&&#+#&)*!!)$'%*&)!($*#+$$*)(%##%*$#*((")'%#!)("""$&"'!"'+#+(&!+$"*#)!#+)*%++%$#%&#!!#"'&$%*$%!"#(!#*$"%)++&#%$+&"&$"#((!("'&&)#$$)$$"+**'$'%(#%
@r3452
GTACACGAGAACCACGGAGCCTGATGTGGTTAAAAGACAGGCACAANCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGNATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGANGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACNGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTG
+
#;;,C+(H0*16C*02'!+9+7.H&%':'7!3E0D<-BG-.3+&D*;$ADG96+10#H=.$,0'=9F=#F@"9@H3CE/3)"0:'B>'4"(/E&?;>F+'B"=%?(H-@$:'G@=7E#.8G&1;0C0=DG(/H@611/'G*,B).;D=1D33>.+8B"GC.@0)&7=1A9B0CH8(A33?GE=85(#F+<D$%E'+6+E.G/7>1,-&/%6"/<E-$H"#95/C*!$B/>12C@5@','2G3,8G7)&0.A;+(H-:&A!;;H<7?!8AG);E%B"71G&2,G791H6!FE7-!>9$#-%>EH&.!9#4%:?;%0"#EDB'%FF4B57)'AFF0264$H:B>@("<&2G&'61$>&37*G'@2%!)(-,@4H8,C);&A#F%G4,>>47!8)*2,$F&(&<6*$B;H;*/05'>F#;3:698E2&5=<%E6F%!H),;G*BF?''3-"A)F?7%-F123'GBG+B;0
@r3453
CCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCTGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAGACAACGGATCAAACTTAAATTTCTGCTCATTTGNCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAA
+
*</**<"D%..)H.E+'<5"CG$3/9&:=!-">7+1B05C0'B":3)6(46'G4F.1<>EF3-?E#'E/<EE3A&!9D0#5BH&46434*,$6</%>;,-+H!&<!6;F)!;0)735708;D)8:!,7H.)H%GF92!-,;>/:=%0%C9!';/,'&F(C4:0(>55&=H)1:>EC3F$3GF1%*0,0(B#7/>(46"@#5&2'B-,95?;E=1?5://A.E.A%B308-<#2;4:1"*B0"*GD?%G575=9?.A=:@'DEB&!:7DG("6946<448FCGH20(A76+)!/#2666@!#4G.58/B17F
@r3454
TTTCGGGTAACGGGCAGAGGCNTTAATGCCTTCGCGCTGTNCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCC
+
F0*D#>:>H46/.C)/?42%5.1%>>"7)&34+**B;+)0473=>$4;(E%+;*5=$0:/"'FD'@H#23'<$C&)?&/=DADHGB/,H71/=$EF+%7H&;/A+"D?>B$$"="(:E.4*$60&B'H(A/10-4*.)DC6H4B<G&9!9/B":D(*H.&C%A:F%$E#6<A8&?F;+0#!&9A:)2088%)G@1%*H-E&-9B%A)@@;3!=:A;.665/3<<$=BA9+;+A+&
@r3455
ATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGGCTTGCTATAGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGACCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAA
+
:C+5"(&9"#"D1D;(78F%.4-*.&H>;G#%-,C)+".$62EF.-1$90;-'E99$(5?"G5E'7+A2'8'8;7E45)9)3B1<!/)831:=E.H%CG7;@B;)/"&C2EE2$B>B!.F%(#8A.C,HE?H22'57B8C-,"2G=1;%($@@1H6-;5>#(6<F&343
@r3456
NCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATNCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACCTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTACGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCANCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCNCCTGCATCGTTCATTCATATATGCATCCTTGTTTTCC
+
$+")'"%&%$+%&#'#$(!**+(#*!+#!(+$*!&*&!#$"'%&*&'(&(#!'(!##*)&)'#*"%+#%'(*%+"&!'(**$("*')#$&%!+*%#($"+!)&)**'*'"*&&&&%)((#)&)"*"#(+(()!'&%)))%#!"')(!$$(("&+)+)$!+*&$(($)%$%()%"&++%$#"+&&$"*#*#"'%+$+")**$$$('!+$'!+('!$((&(')%'%()##++$*'#+##+*&'"#($*%'$#)$'(&)$$&)*$($")&("('*()%#*))&)&&"!$'(("'(())%()&*)+&)
@r3457
CCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCNGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAANAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGNGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAAACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTAGTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGGACCTGATGAACAAACTGGATACGATTGGATTCCACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTNGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAACCACATTCCCCTGGTTCAGANCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAGAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTT
+
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
@r3458
NTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATAATGCGCTAACAGTAGGGAAACTGCGTGTTCAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGNAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTT
+
"9,*4&=&#',2(E$H!DD>$8&<,47;5*:G<G$0.)-6CDE1*C#FB.7F(G?8<C5F:,:G!@1-6G@,</A:6%G72:517=H+;F304!"#+#+4)""@%:B4%=>%%@4:9@@+:@'*.=:$)CC9D2B*E$.112*3,#@.8(<?"!@$?G51+AD#A=>?=.<>#6+52:.2=6.GFC51(51=0=:+A:81=.-9H67?'@A$>8$G'7%@C?+!1C!#A!(A%7!!<AD:%HC-CEE(G&*$5B"A66(E)C5A0$HG&)CE=1&21*$5&.(584?4A+,2D=&=("EA@-(AE6C$8
@r3459
NGATGTTGTTCCTAACCTTGCCGGGAATGGCTTNGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTNAGACGAAGCGAGCCTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTNTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAG
+
&=;),666:(D<@F),2C)583BA?(121=B=C6,#$?E%D!,CG>F9/(F15,A5;G767?/./,FF6&90*DA"DE:!;*4=??>;$8$A3:5<!3HHB2935)H!H,@&(<,E(;HC7;D,)"C.E+B?:G4&5B315C9"/742<65H?F@26";@GC"DH/D+$@D20C)A@8;*BA/>;&&FGGB*2,?&1FF0<"+HD%C1=("!D@&06/C,@83F)&@)$=#D?"$<"73G1?:%!.G4"(@**A7-2G
@r3460
TTCCTCGGCACNGAATCTCCTTTGGCGTTTCCNGATGTCCGTCACGACATGGGATCCANTGANGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTNTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGNTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTNCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCNCTGATGCCAATCCACGTGGTGTAA
+
E7'!4!0;40H6E'?3&5(BGB.A@@36BB4>B?@/6C-*#'&&E&2:&(CH8,-<EF=E-.<?*+4@E)1H%B8?.-+F-$,'2=A:$F8'FE&0'?53F8A&&??+;B(83A!:*CA"5AB0'63**G%,%6,$G&B/2-8"=.;24<-6://#51+1D7.=*G*>;'@F"A00/;#:G28.2#35'F'&-G(()B#A.",!=;"*=;AF0)10&.F7*,5(G-,7#E7$<6CF='*$>=B(5G+E/8%0&4>)A=D'>HG+09G,;$?-@-1!)'=B'335;1*8,87C($@$+6/D;%!4$5(6&4:8+
@r3461
CAATCCAGTGCAAANCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCANACCTTTCCGCCATATCTGTAGTGAATGTCTGTTATGAGCGAGG
+
0</(=.C'B%AC0''GE2@02A-86!09";A3.906*#9@(:$G"#419@%893"5D$)86D+;77.&##>8HE(>B1$6<G#+1@%(7*=45)=G7/B%/%.=,5$D9<=".2!9;BE8;6H/E'?D'>3*<')#D,3+9'A98/1;.:-CGE7:%!$58589+1$#
@r3462
CGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGNGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGNGCCGGAGGATTCAAATNCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCATCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATNTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCNCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCANGTTATACAGTGNGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTNGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGNCGTNAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTG
+
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
@r3463
CGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCCTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTAT
+
+2G0?D1#<E&&H="?%C@BH";&2F,*@(<%@93$;:E,:)2-;@97@?-A5,:82=H#5+,=GF2BB#/4"=913@*@$970)-'H5?&BG?(1+:'4<2$+"D(6G2-D)F04;D#<6B&.52,
@r3464
CAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACNTTCGTAAATGGATTGNTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTNATTAATATACTTCTGGGTTCCTTCCAGTTGTTTGTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTAGCCACGCCGGAGGCGGTGGTGGCTTCACGCANTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTNTCAGCTTTAGCATCAGCTA
+
!1"24;%,H>D4"<D63E**@@H1((A3E!%!GD:>0'),3*'D4DAA1911.(CH".EF:>$39>*'<,5:F'BH!1?64==B#"8'/1GG;2G4278"6(%95<A57?='%@:6'27772=H#@+8;:'-.2D5519:G4:5+A%-EFC2=22#-",+%:3B-<4&/"G0F4D.HC/,8$>8H#+.D%BC2B+9D<*F4.D#E;#)!$E(6(?/""EG29?)H=?91<#12G2((F6*8D;89CD($39E.+))%G73@9+4$6=:'4:.6(0+EB!&%C/F4G"'HF?7'%2@F3;.#<)*BC!-H7.H=F56#:?+D8=.@*''8-*G/H'H"81.H?7,$/5)H45<%>@:BBEG06.,F6#../";;'8!8%!17E@B(?)3.B=5%$D;GEG47A$*%$(&5D0%"
@r3465
CCATGCTTGCNGGGATGTCATCCACGGAGTATGCCGACTGGCACCGC
+
3)2!:(G.&0#2-BDA5+!!2@8&@/E8/(%G$23).4D7H=A4.4#
@r3466
ATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGNTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGAT
+
)#*)+"$&$!)!"!!$%$""#*"+&!++((%&'%)+&$*)()*#!"#''!%#*)')"&*!')*)*')%)"*()!)"'$#)$&")'%%%*'(!&)#&#)'*))!)"(&*"!""('*!&"*&&!+$+*"(*#%""'$%"&%)+)%(&(#)+#%)!*#"&""#)($+(%&&'&'!
@r3467
CGNAAGGCGNACTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAANACNTATACCCGCCGGAATGGTGCAGAAATGNCGATATCCNGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAANAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGATGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGNCGGAAGGGGATGAACCGCTTCCCGGTGNCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGAGCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACNGCNAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCNTTTCGGATCGATCACGATGATATTCACCACACCCCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGNCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCG
+
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
@r3468
AAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCGATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTNTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCNGNTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGG
+
+31E$=DCE+'@07@<,";H$)5?A>A2;#0!33D;E.+!;/!D@89%4(FC-44A3E!=(13H-8A%$DD,)>;?F*E0(5C,"+:+<)7#74/C*B2$8901H>==$2=3+AC3-F&CCG1(=8:.>:<(CEA#<@?0<&*E&@C##@)5-:G$."#=@)E.(GA59E6/+,6D113A-(,()4?<!)2C7-:"@)G.7$)'G,4CF;($G-:H7.,<&,$(&<0=9D#46(B;$GG,'1&:D:2AG#34,=572E48=)<&)<G&.F);!=E'=C##80*7-8A-,#G:43;G&C19D93@D/C.9:=*#$F>A05.743(2&A7;H':,9=
@r3469
TCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGT
+
F';E',<$6"2=.;,!/&)D4C&@%B@3D!E,*CCHF!6$&/*2"#()29"%'EC'
@r3470
TGTTAAAATATCTGCGGCCTCATCTTTTGCCCGCAGGCTAANGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCC
+
67#FF9EH'");C%6!B28EC!42<89?"0"/20*AA&48?@4=:4#:!27CB'1";.,6%,?842C2>#=/)2?0H$+9<$"(:<=01G2"3=<"$
@r3471
TGTCATNAAACCTNNCGCACTCCAGAGAAGCACAAAGCCTNGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCNGTGATNTCAAACGACGCAGCTGACTTCNTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGNGAATGTCTGTTATGAGCGAGGAGCGGAAGTNAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTNCTTG
+
&"*)()#"%%*('!&+""##&+)$&)%'!%)'*$*%(&!))$+%"'!"')'"!*$+#%*&*"$)(!**&)%$)$*$%'*!#*+('!!(!)$!"!%$(*"'*)*'"+#*#'$$#*$$%""(&)&$"%'''%&'("!'*"*%#!&+#""$'"$&(%"#(""%'(*$("!#"")+*(*&"%&&&*+'*'#')#)"%#%*"+("#)+**+"+&&+&+%+)+''%")+#+&(*%%%%&*'*+(&*(+("""%#*!"$)(%&()*&)""*$!!''+'!!))*%&
@r3472
TGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATTACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGT
+
*3AB(4&$1D)(96-)+52A<)FA5;?%$(DC0(4H4;##7BF)*?0-#;>4A,07EF$=.H"''*E8)9*77*H2B()D3#A3'088173:3)D+-9,/13A.40F5-!0==;D#(+?/D,#)?;0CC.9F*=/G@$+DH"*<#%<3.@;(2A51D)#+'+F)(1&$D4.=63"7$):@,!B=08"+=@/8:$(!.):*&,9&66%<3
@r3473
ATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCNGGTCAA
+
8-A1?*17#3;2AFB7=/H.?H3%C$('>63#,:)-#F%848G:HD;:BG67F$CA$8G>8>@#E%*H5=>)-A2*8#?9=6+&C.C#$A)#$'&";$)AE=<(B%56G'0E8/$&A,9.;"1"(!B-E8-5!9/E+'@-GD2)H?D%9A'GC>2-31*G-!:6
@r3474
TTTCCTGCGGTAGTGGTCACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAAAATCGCATCATGCAGCNTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCNGAACAAGAGCCGGTATCGAATCTT
+
+%&%!+*#'($)"$&#!!'$%*!&)'&)*$$&#+&%$#'&)+($*#$("*"*((!*$*%""*"##'$)+!$$$%)(!"+'+$'()*$)%!!$$%"('!*)%)&+'*'%+$'+*&!")'"%"+$)&""&)"(&##&)$*$%%+)'))*#((!&&%%&&%')#)*%!)'$$"($!(()!+''++$"&!#!$('*+$%$$(((!)$""*$+"&"
@r3475
GGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGANCTGACCGC
+
?+:1@.7C.0;2+",$0&G6%A;%4F;8".):BB,,."6D#;C+8"+H'&6-C-(*-+?$%52EGF%%B#/.F6:;E.B4*><%0B/0/7".
@r3476
TAANGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACGATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTCA
+
'(%$%+*+)&$'++''(&)'"*#(&"#(+*+&*+)#%"+!"'!##$$''%(&+#)!&!#'#!$%%"%!!&"+%"+&*"#!'#+*!(#)+&#%%+$&"#*!)*$!+#)#'')++
@r3477
ATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCTTCTCCGNTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAGGAAGAACTGGCGCTCCGTGTGNCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGTACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCAGGCCACGCGGGATTAACCTGTGGCATGTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGNCGGTGTGGCAGCCGAAATGACAGAGCNCGGCCTGGCCAGAATGCAATANCGGGAGGCGNTGTTGCTGATTTCGATAACCTGTTCGATGCNCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTG
+
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
@r3478
NTCACCCGTAAATTACGTGACGGATGGAANCGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATC
+
%'B73%";96CA.B3*@$2++EBG0/*/=;2:G-0*0#9=:A8!8-!3-??ED=8B%30!&6-8!*1.!H*8D3E;7
@r3479
NGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGCACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCCCCGTCGGTGGTGCCATCCCACGCAACCAGCTTACNGGTGGAGGCGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATTCGCCGGGAGCGGTTGCGGTATGAGCCGGGTCGCTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGTTCCAGCGCAGTGTCACTGCGCGCCTNTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGNCTGTTNTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCNGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGGGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCNCTTTGGTCATTCGCCCTCCAGAGNGACGGGATTTACGTGCATCCAGTGCATCACGCANGACGGTGATCGCATCGGTNCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGAACGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGNTATATNCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATNCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCAAACCCTGTTTCTCCGCAGCACCGTAATAACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGTCCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTAACGCACACGGGCGATTCAGNGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCNCTGNCAGCCTGTTGCATACGGGCGATAANGCCGTTCAAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCANCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCGAGCTGGCCTGCAAGCGCACAAAANAAAA
+
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
@r3480
TTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGNCAAGAATCCCAAATGGATANTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGCCCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCACCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACNCATCAGCCTCATTTCTAAATATGAAGAGTTNAGACGTAATGAACCACAGATTNAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCNGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGGCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGTGCTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTAATTCCCCAGTAGTACTGCAAGAGGTTCCAAANTCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATNCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCNGAAAGAACAACANTATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACANAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTACATCAGGTGAAAAATGTCCATTTTGTGGTNATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTCATGCCTTTTAATTTAGNTCCATCGTGCCGCGACTGCAATATGNGAGAGAAAGGTCAAGTTTACGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAANGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACCGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTT
+
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
@r3481
TTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAA
+
8(4=,4@C*)E664-C(/C%3?+#**+275++3;'/H673B*:HG.?C
@r3482
CCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCTTTACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGTTGAACAACTGAACNGTGATGTCAGCCTGACGGGGACGAAAGAAGAACNGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGA
+
G.1;99C/#!C4%;F./>,"&/@=:=E&;45A&(<>@@.#,2!1D0FB,E7D;@'6&12F1,&A4"D&EE@19AGH=?*?C6*CGB<F4)(C94+D?DF%(:G&E)3'*)&@$,--:/.:C43*&$G-7,6B(1<F2C>+:*.8#)=929<>.(-9?$5,<0>D;6?53&>3#*-C/2GH;D,$..D#44+&"#4;%"9@<E+F?*-@AH
@r3483
CATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTNCGTCGCTGCTGGCGCTGGCCCCGTGG
+
'1=*G9C?*;)(-++3=4!289GF,F6C<6A#!$'$7F?#8#A0?72CEFAG9E,/)2)?=)(F5*5-2F9.EF@7(.+7)G5F>/AG9=!C8%=#*G=)+&)05G)!G7$G#+6=@'.=
@r3484
NNNTANTTCTACNAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCTTCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTT
+
#$&'&")&*')''+$()#((*!&$)(&+%*#""'%!!%+)"!&%##"')&(#'$+!#*+&)&"+#%!")#(%+(&*$(*$#'%&$##+#$$#+$+)(&*+*)%%#$)*%&$%%!)(&#"%*)%!""(+')*+*%)*#''+*%(**!%+!$"
@r3485
TTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACNGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTNGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCACGTATACAGACAACGGATANCGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCAGCCTGTTCTGTACGGNGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCT
+
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
@r3486
CTCATGCAAAAAANATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCNTA
+
5H%!&)0A956@HF%<.=2-806&G@2")@0#-&)*+<C7C1'227$$;.BGG1H2/'40)F4>6H'5B587&-./"/4:/22):H*"/;;E49='5-"!@+4+1.;??D053*$8<.2*D5<:!7)6
@r3487
AGCCNGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGNCATTCGCCCTCCTGAGAGACGGGATTTAAGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCNGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACG
+
(%(&!+#$%(+&)&$($&+"!!+"$((%+&*%%*#*"))*("!#%)%&#"((*$(&''%''((&$%$*"(*$(*'#*'%)+$)++#"!%""#++""+'()$+%%*!#'%")***%*$&%$&$)'$$#%(("(*)#!!+**'"""'#&)#+#$$)"')($#'+%*(!(*)"()'+%!)')!)(*#"#)'+&#*#&*'(&#)!))&*
@r3488
GGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGC
+
-G7B"<&87?05$44H$?HAG685&,A;595-=38./&D9)4%!(*+-7#8'<:-G-CG1*<5%5*E*4&021!"0>C0;A"/C1*81+;>?6BD62:A16;(>/6?%4B9ED>D93*)'H*7F(:-ED$HD/9).;/+*G:6;D+('-9+EG+;/)&17!&-0(;++?*4#AG*<E5,:!'1'&*C@(6:%;,G*@3C$?*:*D8/)A"#=F?1(#1+8F$C4%4-*%4G$ED'+FG/>18-E;3%H58C)05'GC5+'/,$?
@r3489
CACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGANGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCNACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCNGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAACGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTGTGCCAGTTCTGCCTC
+
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
@r3490
CACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACANACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCT
+
@.6(#;<>FF@1%=3B,+AD.3?:1A/#B*-F0"+C%;FE80B9!B<?4%-21$&=+A6"=*D51+$5B7/3>67",;?$CH.-27,B@/$G@)7HC."0E.1AGDDB;7D3D<D!D$4?9GG#?>G63F'0B$?<-&?F",,$".(;')!11H$0&E<B5E.,#!>&,4*6B1)@'@&/<;@<<37:?>+=H<AG+E-<5(,G9&G498A73-F@1$#28""<<><-$'044@?$)H!:64//#?E;D(B:.=F2C4'BD39AB10F(*%(H39G-D)&:&5F=:H.C+G2#H:/?>>%?F;8&*+,3(!)90422A6F(B'44.>H%)"&
@r3491
AAGTCCGGCATNTCAATNCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCNCCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCTGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGANATATTCACGCAGGGGA
+
A43!>D4;&?77<:0'G(-CD$986+H?',F>8AA,#6<*6@3/=?0+;@'%"#;*5&B@6%(5-?"1.7&2)C!BFA(,<?:2!!!60&><@+E)'2,(*#2>EHAFB**F6;E/&E6-D<7(G6+4(3$.4:E8?C@+?&.A%5.*585F@%H&A*"47$3*2,7,/A3:7$D,5H+A<@"98"$'B<7#F<21$>'2:B7<1/BH'$7E,5.$9,$6G*/573%:+#C2G,;),@G&"0'#9/+#09?FH(1!4:'%$?G6'F@7<G7"%BF&2,CG/FA75-(ECAC@>)FCE3.8:#3-%)=D5G@/
@r3492
CTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGNTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCC
+
C"HB(:3(?H%:@*&6/CB@G21G,37/0='*DH;8.<(89,;;(9>(*+,&/6"-3<4F1D%!3(21HH/>0,<D9<@:%3'D=#B@),3@&;:86%,*.H%;6?%2D:50B8FA=%=,5A=6<6</5EH)7)<+ED+E2-&-@,FE@2$.:3=>B-5778G$-(,A3#H<D,2?-2A:$,A-DF,=2(.1E"?(+
@r3493
AGANTTATCTTCTTTGCATTCACCGCTCCGATAACACCGCATCATGCANCTTACCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAANCATTTTCTGAA
+
&"!#*'%+%+%!!!%%('#%'*'*"%#&+#*($&(%*#*$$$"'$*%%**+)$)()%'#$#"$!%$!'$&)&(#$)(++()*)#$!!'('($&*+*%!*#!#(#%$#'$&"*"*)!$#('$"!+#"')+#*#'*"+$!+#(%&%)'!#(!'%"##$*#!$**'+!&)(#*&%)(
@r3494
ATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCNCATCGGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAG
+
2=0@#1:A6((F"<!:#4,)"G2;?>G=12)G04,@1G0!+1.$#<D0@=H*=D&:#28+C:95<47-ED1HGAD*;?D"388+*40=(2=:)*?G98F@F4@5.9HH:A9AA&C$063:(74,D5H;@!":14?4
@r3495
TCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTATAAATGTATAGCGAGGCAAAGGCTACTCTTNTTTNATCTTACATTGAAGAAAATGANATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTAAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAANATTACGACTTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGTGTGACGNTGTGNTTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTNACAGAAGAGCAATCTGTGGTTTTNTGCGCAGCN
+
D!$,-&@-1F<@+4:?7*%E1/)0E+>:%*(4>G;4=E@"C>355>"!$7F+:+9@5<1'(..'F+B#0'ED--'?DA?A->6!A86A1ADD*9):A8/7610#G=?6*BB6?>A3#C7.'D!2F;4/3#7E@!++"11F'":903/7:&&A25-1@E4;'+B"#%BD<*B,43;80%+93;=9H+;5#7@*.$=9*"=<5-+7&'?=9#5)2&6+;)!*&E8.)7;1D5(>DA*47%%"%4.)*?!&-.#5<%G9>94@:D&GE)F;<96*,77?!GDH@/A?A0?&9A-?<+*C%(9C071;%=:1*&G!:!/"A02;*H#""G:ECD+#.#*)BE:7E<;>'4/59)9&FBADA5&%4#:5>F=7C1F59,%,D*B#*85?(27E%&<%$2.E$;*H-:*,G;F78%:(@7$D@>87-A/<HG-/G"&=.H<B&#@#AC#$
@r3496
CAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGT
+
#8816<5H,=(,?%*;50F*7"C%0AA=F7?12-/6@6#,%01E5%94F7D7#"
@r3497
CGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTNGTCAACGGAAACAGTTACGCCGATCNGGAGCTGGAGGTGATCANCCGCTGGCGCATTGAGCAGTGCAGCGANCTGAGCGCGGTGAGTGCCTCC
+
;!HF-+2=$B@4C3,-(")/%":FB)A5<?8!H=4$A.B>AG7=@@)0(1==+)=@(1:5GD85!?GH<2!%5GH9/=5,5B%G(!B%A(D)5<&F,:1<1:43(H:.$>&+)8-H9-'9E?4(!>C+$@0A
@r3498
TGNCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCNNCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGANGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGNGCCGGGCAGG
+
'7B99G>:@$>2>2'7F4*5#..C(?4*<4E/B:-)G;;96H'/($3--8:8"6=5&2>4!%>)7?0*+H%%AA3F?2,6%1+%A>8>%".;7<;G!24"9$5AA6'42EF5*%D)H?3'!$7A2+.6(.@4-/3&++.?(9C:B@C=05EF@#2*!2@+4($+":;A7C;?"AG2H7D;)9)*?A!;CF?!4$#'66!;!2).5D<'<)+("@=>)E;4+((+%:-/4A:1*7H/A6/,#E(>G19A2&#B8"",)07=B,6B?(H9F+*9!=@,F<75)=/;&1'#&0A'.7':<2")E)B$!!F,#(@?7C"4E-=4$D?(9(&=4C/HD1F3%>@0HE=?%$F1F0/'?""()H//&F<$##D7/
@r3499
CACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGNGTTCTCGCCCTCCGTCGCTGGCCCCACGTCAGTAACGTCAGC
+
2-=0%@&H>?$2D3:$A-'@>$1#*#6=F$")9>#92>1*<<8+6%?(/1E445.<:54#+1=?,)17?(9H75F!>,BE*")A@D()H(7HF(,$2@;?/1#,9%'E-5A!2%EB497D1H!):F>2+.'#:B;!0+!>B&?FF4G3H)/B8#>0.CHE432!,D7B27;5F;7(6A(@G5&#>7!HEC#H
@r3500
GCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGACGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCNCTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTTTCGACATACTTAATCAGCCAGGAGTCCCAACGAATNGATCAAACACTTATGGCTATCCAGACT
+
*++'#)"&((#&)#*)!$++'+''&)%)#&)')&(!)*!+!$*))&*"(%"$'(%%($*)&$((#(+!%((*($$+%'!*+*#'(%*+#)('+#"$+%$()(#(('#$&!+"%'+$++*+$&'*++'+!%*+*$+(!+#$*&')"(&'+($!))$(&%+#*!((#*'"%!&!)($(**&$&(%*")&)"!!%(+"*+'%#()!)#!!+())##$+##$&'+(!')%(*(((")')&$"$""*"#'+!+'&'+"*)"#&$!!*+!)!#"&'($"('%$#+'#'"+('!!!*$')%+$%+('#$(""*+#%"*$'!"$&+'%+*+$#!$"$))#&##+"&*+)**(%+$))$&#%$("!&"!%%#)%+())!&)$%&*%)"*+"+%")&('(+')$!**+"#*)
@r3501
TAAACAGGAGCCGACTTGTNCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGANATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGC
+
@&,>#)B:<.*B">2.5#:D6=,?**'AG<D=!1H-6E)!=0C>)9%?+)?12*3G'=6$2"):<H&@'+1>:%;>G8#0@98+;17&$2E/$.?')6=&1G9F56AD,=#:*1=:D?!BA/=9##;<.<?:
@r3502
ANGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTNATTCCTCTGCTGGCCAGGATTTTTTCGTATCTATCAAGCCATGAATGTAACGTAACGGAATTATCANTGTTGATTCTCAGAGGCTTGTGTTTNTNTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGA
+
5/G".#?"9+"6?'G#AA.%"-0$/?<4)D./*787<<?C@.?;)51D.8024;G:/%DF#'@?A6*69@E.1&%20<:+$5&+97>95$#)'D>3-;7?#-A)"D#?8'?8D$>C62#G&=-0,<"$)16'BH75/%DA55&/341?)#H&01:44HG1=9')G#D!45)3$>6:-,620HD6A60A73'35GH0/(>'88B&F*"5#3H#B.,
@r3503
CCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGNCGTAATTATCATCTGCGCGNGCGTATTCTGCAGGTGCCGTCGAACAATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCAT
+
*/5*!40B>4C6?C2#@,G5@!>@/20!:&"()=72?GDF$<:5)1%<+*$/?,B1/?-,-@9@!5C233*@,11>>G.@DF+(!3-AB?)-<!B.+2"%20146!91'0A*&4980C,'H5CA-8GE#-"3E""D?6G()*,93B&))D,+8'D<C@(+HF+A.3(7G2<A/G,@;;9,2F:5?AA>*>@#:HDD,?!?,7>#D5"9*##1:&A#7+'=$4=.-E&9H"5&1*:'2F.2%&2-&F+E+F4/".+G.$F77%$*=9(.9?B<"6H
@r3504
ACCACTTCGATGATTAACGGNAGTTCATCTGCTTTATAGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGAGAAGCAGG
+
'&7.<64)79=D%=##E9::<&B"?C>@&*/!#;C?FEHGDG5A1D5:EH:GF)B,'&C%FA5D=-$D(=C'E;E<<0"+/15C'2A=*+@-=H8-!;@:A3%;&G/2>8*3";7@<23G55D.%B)*?06)<##+:7(%@C30;D7*4$4@"1#1%5='"%H1E=#=>F91B>-.;F0:<,+@2)<F*@<0,!/@@:4*%2$A$D6A2&!:9;7-A><*:@+;F.E:5B(.H=F+/84(@%>&;@9<8:3@8*)$8C4BD
@r3505
CCGGCNTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGNGCGAAATTAACTCTCAGGCACTGCGTGAANCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCNATGAATTGGTAACACCANCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACT
+
%"#")+)((#+&+#)+'!%$*("*$*#$))("$+&%''))"*)+(*$#$$#)$##('!*)"($(*"%#&"%$$&$('+!$')+"")+$(!*+**#)*"!(%%!&+"%&)*'$+!(+(%!)#+&)*'****)!(%+&(##$#%'#$&+'!('&#$*&((#**)&%+&)'%(!+!)''%!'%#%#!(+"(##)'$%'&"%'+''%+&)&+#%+)"&"##!()"$%()%$$+##''"&%)$))*!+&(#"))()&&+++(+%+++
@r3506
NTCTGAAGCTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGTCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCNATGCTGCCCGGTGTACCGACATAGCCGCCGGTGGCA
+
#%)!##')+*"%$*!+!')%#)($(!%('*#""#&#'(&#"**$)**"%)&#$(+*+&)""'"&)+)+()*+!")$!)$*+&%+%)!*(%)()'$!*'!%)!()*+'+)'!!'*'(+"+)*$"!*"!%!*!+(!(&$#%%&)!&)$%+#*&"+(*#)!*$)**%+*%!+"*!'%$**(###(%)&"
@r3507
GGNACGCTTNNGNGCGTTCCACNCCTGAAGTGTCAAGTACATCGCAAAGTCTNCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCNTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCANGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGAGGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCNATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTNNCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGNATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACGGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATNATAATTTTGCACGGTATCAGTCATNTCTCGCACATGGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTNATGGAATATTNGTATGCCGACTCTATATCTATANCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATGTGCACNACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTNCAATGTATGACGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTGTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCNTTTTCACAAGCGTTATCTTTTACAAAACCGATCACACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTNACCTGCATCCTGAACCCATTGACCTCCAACCCCGTNATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTAGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATNACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTNCCCCCGTCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTATCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGNCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTNTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTNCACGAAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATGCTCCTGGCANCTTGCACNAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCANAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCNGCGCATTTGCTTCGTTTATGCG
+
*#''&%%*#'"'%+"("#('#!)!#!"!"'$**+"''*+#"$"#)'$#'"''$!+(*%#!$**#%$'('*(#&*$*!&"$"#%#+"(&'%#$+&*%+$$!$(!()&%(+(#&+)!&!+"%$++""""''(!"'+''&#&''!!+&##($'()++'#")*#*$#$++!)($)(+%!(!$'&+'*%$$"(!!%*$&++*#$$'+&(''(*#$%('"*(!***!"'!'%!!!*")!)%"*'*#+*!##"&)%&+'#&&)!%$*!$#!!!)$")$&&)(&!!+(%)&&'$#%)*'%+++"')("!+'*$!!%&!&)$+#"+($#(%)&%+"+*"%(((#+%%+($))+#*)$)&(&'('#"(#*$)#)%"%)""'(%)*#+&&&'''++'#%&)!)+$*(!')#!"'($%&%&#$(&'%)*"%!$*'(%!+#)('*#!(%")$&&&+*'*'(%$+)"(&"###%'+'&*&(")*!&!%+*$+#(('(!$&*'$+%)%+!"$!)#!&+%%&#"#('!))(+!*+)'*+!'+"!#*%$%$*)!(*'%%(%)%!(!!!"*&$+$"&&#'"&!+#+&*&'*!)+%"+))#$&#*###*&&&('++%#+())*+*&"(#*+#"%''+*%!$#*&%!)+!!*%%$'#&"$((!%*''*!%$$$"$(*'*$++#%('(%(*#'*%&)"!)&'#+("""*()&$!($#)"')!(%"&#("+"!(+!$)$$*#("*'!'$##!$""&!%**+%&("'%"'"!$"!")%"+)%+($"!#(***(&"'""#$"$)$&"+%)+$'+#$+#$'((*%$+)(##'+$%')*(*"$'*"))#+&%'"&*&)(($!!$++*$'%%*(*"&$##$!%(%)#)$%%()+*"+#+%'"&%)&#*$"(#""!(*(&%))+*&*)&)%((%'+('("(%&%+%#!%#'%##!+%(&+#&)%)!$(+'*(!"!))$)$%%$&$**#$)())&)%(!(!&+!)$*"%%!'%!)""&!((')('()(+#)"#(+("+#'+!)#*(&+)!%*'*()'#$*#*'!**&!&*#*!$!%!+$'$!!$("&%(')*#'+"+$!)*'+)%"'$*$!%"#+!%*'""!$*&(*)(#)#)**"!"""'$#*#$++!"!&')''$(((&#!**%("#))'"+#(!&'+'"(')%**$%('$%&)'(#%"$*$%#!(%&&(!+'+((++$+*&()#++)''%%&)#""!$%"&'%'(!(''$""%'++'!($#$#)"*!%*$"!*+$'('+"))$"#+$+''($$('(#'"')$!(&%*#(+($"%*''$"!"("$!(+&&!+#')$$!(%*+%(")%$'%*)#&!)'+'#"$(%#%##%$%*''%&$*#&(('##))&&#)'%%!+#*$*!"&'*+)%'$+*"*#+)%##*!!"("))'!*#'*"!)"%#$&#"$&*$!!""(("!""+*!'!)%#+&$'+$)#*'%)%#%#!#*")%*+!'+!"!*)!$+##')#*)(%!"()$&$%+"(+'"$*$!%$('(+*!""$+#'#%'&#*)!)%)#$$
@r3508
CCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGACAGCCAGAACGCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTANTTCTCCTCACTGGATAANATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAANGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGT
+
.B;>F1(G-:?>;-.8%1:$G#E7.+%$9*/E;H#0E>@9$@9#A+5A/66)/7CH.4?@;6<)3.*>3>AB3=+-D:86H1.H1D"+/3=":=0E3.DE.47!:DB52FG@)F+;HE1G'6A#8=D,<A"6<2453;((7%:0&D2:2$9:4C1?0F:C6A).(.;"48$B-B.16'/A7A6.7*-,?8+-F2H48F@98.?,!D8<F#0$+=%?;=107/'*$@F0"*?&B;%:+22G>/82.E>>G4)HE$"%/)G&GC)>-F(';(&
@r3509
CTTCCTGCCTTCATTAAGGGCTGCGCACAAANCCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTAT
+
/:=%H)8F--(F>:@($-'>#.>-E0E7@9D:8<"<&CA#*=#:=<?A$$.0*3%@.7-"2+<%.9=;+E=F;$#';FD%'49&/6619'5-9*"("$8#*,DD!;;.?15-1?E+320D&&.(05D"%:,..'<%66+"-+74*24BG+D?%BF&>B#/,6A5&>C;)&:3=>)-(%G
@r3510
GTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCAGCGNTGATCCCANCTCATTTTCATATCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCNTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAAGTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCG
+
G+0EE>H)$?;1+EFE!4'93$:7@7@44?GD:0=*7A@;4:+F#,)GAF*,4>31/"C$-CHA+A)>HE."A+@C$%*<),#->*7>>$@7+<'.=-A%36A:#5776-*"/8:-*3G"F;F()8B1$=8695&>>7$C1!4G""!)-"2/;%4F;#:@8&=A6G1'>98F.3D59$:!0<?G4B/;%DF=GH-!A')E35F81=D+GE"0C4:,</8=/5%-6H%@;,)<%5'8':<C$>5A#5!%26DA6A%,'H#G>HHC,D5':<EFB0E<6-</<!95CF!&*7CB%%*%=8#7+H3A)"A$/F==*C=A0?9<C5.BE!>-2?;?%$AF??3(?@B$84)0-+).,)>='##7F0;0E*5F<3.>AEBH"?EF-32+(AE+-C$#?AB;/'+3FA,D/
@r3511
NTTGTGTAGTGTTCTNAAAGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGGAATGTGATTTCTCTTGGTTTCAACCTATNATAGGACGTTTCTATAAGATGCGAGTTTCTTNAGAATTTAACATTTACAACCTATTTAAGTCCTTTTATNAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGNCGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGNCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAANTGGCAACCTGAGCCATTGGNAAAA
+
#&:75GB#!++?8,$$+,.?:(#>..AF$;-F(")5"(H;79$DC71/7*1&="=#&>5A9B%F+D8"!9C2@0.F>"BE>:<&:&&-"D9HE#7<;(7+:-<DEB"C,D1A/BH5=#(>'BA-G-9F9;'49$&)G$9C9$0,&;A):<#BE!$<EB)7'!-@:/(3!8D#(A2%<,0/6.<+@)?.9-="=->CF$%$?7.##*27EB'9F(1)!2F*>&A:14$:&+G=,1FF=@E=63'7=+:805#&6"8+G@0&".+(*6.E!>8+,63>""62#7;>%6#H,$EG()/%#D36>)G8)&:-,7(%5.+21B6+>,,(!+E0H?>>.:D3@667HA4F&)6)9<=@#:HDADE.9=5%%4&GH+<*6#415/7&32<!ABGB.FCF55#,63E'*D--(
@r3512
TGCAGATCTGGAAATTGCAACGNAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGNTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCG
+
.;).79D!;&+A+8EH%9,?9G1E<$,740(;$.AAD!-/$?2./,>E$*H"%7@#4:AH.??D:E=-")!3&%85C%)1<86.3?8(!?80/-CE5A!@"11D#6$E+C&5=>2?)'!%E2HH@4/&<9&%6%5'ACA.2-"/')*<$3*86,+$C8'%*$/14!-FEA-(@>G:C2>)+-1?7&CB;!>92+<<+D./6HE7&7D<:;**,721C&%@/9'-<%@-+'D9D(:4%;66;/=5;*0#)7:99%8$D!-"H58=:H>2&%)C6"@9->;4')&C7D<?;DHD5!::"E.#&)D7.@EG4'&9>8G?BG#@&03362-
@r3513
GCGGTGACGACTATCAGGAAATTTTTGCCCNGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATNTCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACNCGGCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGT
+
=.,%35(++2?7-*(A.D8-)F%5':.22'$8?:&%H").8*+%270&"3;HH;.96E4:#FB!*F"41;3/.C'E(*%+F9-;H+4*@#/&"H@29B0H*D,#?5'D=6%*6"3!BA23&6(4,A7?77?.)C&2.=8#?2<'(3).-;/0>)91(62B$!;$-BE%((.84:.#8H*,7??:FH5C9?!<=0D+H<>:!##+2+"90?BH!;*08D($*+FB,2G$-.,!&*DF?8#02'''-:0:19+1/>14/)H='@=F%F+%/$@C/!0?63$931&DH3A;310A0>$340330=?EC0?8>+E:B6$C3&#%#(,*%A/-ED)D?
@r3514
AGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGC
+
H4"0C>"F<43GH3>H7.%,7+3ED;=E1D0H&HH6@*C7)4AFA+0-$?&:F>*G5=3727'B14A59+2#)'';(<:;0A1"3#E,F';?D<-3C%+9=3=))@6#!2C&0D>,;"
@r3515
TGTTTTGATGTAACCACNTACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGNTCTTCTGTAAGGTTTAGAATTACTGATCGCA
+
627D<6+13!#&:%"!6+%G2&AG<:/5!C+2:"B5:C)!C7;#4E1:'C568B>--8@G>@#=",--;<);$G;5A4.A71'0D,"1F"-(;%
@r3516
ATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACNGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTNGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGNGAAGGCATTTACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCT
+
-&C7F4.7+E/C*4@A/;D-4+==G//4!,36)F':D1,7G*0C488@A$%79F1@>9?/4'9=AC8D='A;.?3-3'8-F%E!2:659%G4&#1+&#$F4B'&&9(%$E"%H))2*'$6D*E7#!(HE&@)@:7>+G533%D"7#.7B3G/80C3&=F-%4!8;!2#78;C;H&*.'FED$!5!=',D7>1#7CG2@;#+(B<>H82?>9E)AB03F!0.=C1F7(47+?B#3!*D&.G.)F#:5*,2'8DC8?8D9@'5+E:>H97;
@r3517
TATCCNTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCANGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCANCGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCNGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCNGAANCACTGGCTTTTTTGGTTGTNCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAG
+
58E<'F!?,@&B&<D'*3<F-@?6*=*93:=G/:C/.G-=,0H/;A@9$86G1?""C)>9!@4C?<2@#>EB'C&7B"H4H%(7.EC'+8,<)=""9H=:D-7@3)&75"4@%)54.'#A0@)0'&.73H1&-4(@%0">(E,3,?9>AF;4+CH>"&%<E-D#@?8@@,2<1<$,$HH*265$*-/C<A1)?3$8&,01*"A:E;6F7;:)+2A+?AG:+=9?#2/)/0D43#:3=9477$=.+.,%H*)F38G4'+6+%@$4%1H'7;6;46#3
@r3518
TCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTNACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCA
+
3=F)F<+BBA95/)@?'!4:(".:;?GG::>38#<H@2>!!-9;8#40H/!C-+CB,&4((%--,'13&'F434(2.),DB$:EG;F:;>24=,A%6B1:GCDED4)5<&"$BC9:+%(3?4D4;250(HB!$0@F="1C<="&4674BG
@r3519
CTTTTGNNAATNCCCGATGTCCGTCACGACATGGGATCCCGTGATGANCTCATTAAAAACACGCTGCAATACCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACNGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTNACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCTGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTTTTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGNCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGNCTTCAGANCAGGCATTCGCGTCTNAATATCCTTTGGTTCCCATCCCGTATAA
+
*#&'%%!#$!$!+%&!%&#'()##$"+)#!(%+$"!#+%*)&+$$!#+!!(("*+#"!*#*%)""($'$+&+$)!()&%!!%*%#(%'$+##$#$%!'+!%*(*!*+++!*$!%&("+#("+"%)&'%!(&)!#'')+"!$&%()%'+*$)&'&*'%*("'))#!#+*('$)$+")*+"%!!%$&&&$*&##'#'&*&(#$&"#!$!!%$$'*%%+$+!'$!)$$*(%%$%$*!)+*+!!)"#)*"""!**')*'"()!#&++$+#!&)$(+%*#)#+%%'##&$''&+*!)!*&+&#!$($%$&&"%%&#+%+")+))'+!!)!)!("+&*'%%")*&*'*$#+&"%"*!&#*#*"%!'$$#"$)&)*'#+*"'!##"'*($!&"#$"%&%!%#"(*($''(&*($"*+"+%&#('*$&(+#&''"'&#&$++##+#)"+%%)%"*""**&*"("$++&*"$($&
@r3520
AAGGTTGACTTAAATTGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAA
+
87"$2H-+$=85&7!<A804#;..,3?=4,!:<('9*/)!C>/--+64GC21+:&D11',;$4H+1(*>&078;=626B/0D?''4?B72!@;G<H
@r3521
TATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCNCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCGACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTNCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCA
+
.4:%?7*-7.-3E$6<1H/=H$@$/E0)/D)&#/)27*(9!B#)"0++.>'40%8<H9+>7$:30B(667>?!:("1)7)A*B)69?G-.;9745DC9.*#443E0F153"E4G),C!F#)"1-'4B&9/C6FC*"/D;+6B>&;B1D!A+?.($HH-=5*)G(:E+,+;80G-G?-$2;H9AG=;:;505#C05?68>3E%*&*AF%"%9+8.19-=C$..9D*%811E';4C+#D+E?8';4'=4.;):?/$6?B:GHH9G/26"H75%:6/6/E$85(?(:DC3@(A<A=8>71BA@?:*?3.GD1:>(?+FBC%!3!23B22#%"'4B/4:1($A85=6%F+7&&)B>?/,07+F-*,C%D$*89:GCA8&G-73771&3B-;6!'3F1=:D58G);"(H*5B5@F5
@r3522
ANNNTGCGCTTCCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCANTCTCTGCATCTTGCCCCCNGCGTCGCGGCACTACGG
+
*&!!+)*$''%$%''"*&&&))&""+$*(+$'&(##$+($###)#!)('('&!$&#$!+!%*(#+'&"%!*')*$*)$&&)'!"''%'$"&'(!(*'*'++'#!!*$+$#$+'+*"'#!&*!)%)*!$%%#)"'$)"'#$"&*%'!*(&$&&#%#)#*
@r3523
CTGGCNCAGTAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGA
+
$!$'&")))"+')"()**!'"$%"$!!!+!'"($((&+$(%'%*%!#+''!#*"%)#!$#"+!*)'!%"+'%"%&$$"%*')*))"+"()&$""*
@r3524
AGNNGACNAGAATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGNTAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTGTACATAAACATTGCTGATACCGTTTAGCTGAAAAGACATACATTGCAAGGAGTTTATAAATGTGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCAGGTGTCTTGTCTCCATGCACACATCACGANGGTGTTTNTGTAGATGAAGGTATAGATNTAGAGTCGGCATACANATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGNTACTTGCCCTCTCTGTACAAAACATATNGATGTTTAAACCCAATATTACANAACAATCCTCGCACTCGCGGAGATTTATTNTATCTGGACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAANTGCACTTCCGAGTCACAGGAGNATGGAATGGAGAGCCATTCAACAGAG
+
)#""&$!*%*&$**'#&**#()+)$(#(!+$+(!!(&($$(#'##*%*+!%!#*"#)"$#'*)##$$%*'&)"#$%!*!'"%**%#%(#$!)&)+%+*%!$#+)!*%*&++$"*('"")+!&')$#+++!"+'!#'&$#&'%"%')#)!$#('')%++'!"$*$)'+)(&+'!'**'+)&$+%+**"$!!"(#&&(%$%*&$$*'!%'")#"(*"!$!&!&!&+)%"*$!'*%$"%*!$!"$$&'(&')#%"%!*+')!!&#''""&'+#")(''"'+*&#')!%'#%""**)&#&)*#*"#&+))+((*!!$$%!)(%&*#)$#!($!$%"$"'')$%')*&!*$#&(**&)()&'++(+("'$*#!)!$*"+!*$#*%%#(&)*'&#(&*'$*+"()!")$!$+%+!(%&!'%&$'*+%(&$%*)'$))%+"#!&)(!)('"(*$!+'%)"%%"!%&*%"+'&#&+(&!)%*$!+()!&+!'#'!"*$!"(!*"'&!"&$$("""(&%+(#*("!(%(%"!%*($(#"(*+*'$&($+')!&#"&((&$!*(!%"')*&)(#!'"&%#(!(%(!()'(("##+!+"+"(%*#'#)%"!%'+!&#)"$!$*&(+!##!%(!#)&""'+%#)((#$!*"&'#!+(&"$%#$"$'"+&$($%!)('%$%!'+"%'!#*("$
@r3525
NGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCGTCAGCTCNGATGCCAATCCACGTGGTGCAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGCNGTGNGATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACNGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATNTCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGCTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCNCATCTCGCT
+
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
@r3526
GTCAAACATCAAAACATGCATCATTGATTACGACTGGAAAGCATAAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTNATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCA
+
D4'?(;C,&':C&?E*8@+3/229B2C=D>7)<:$$2,1(?DD&/D8>1?1G-*:@.;A1+397A.&55D(@1D,"DD2%0'748$EFE/#4E6,;&%)#1H7!(9@$%"D2:&*)8.*($9H/,84C-G@&1A2EH5&8A)B(*-(;(6,B2'25F=)E,/528,44@6*G4/C.'1G).G$E.F527,.F>6,8@*"-9E@2;>7HA-"/C>2C?(5+#0C/$=,H.:819F4<3!$E$01@<'/A,&$2->8:,29*G#;F?)0>(
@r3527
CTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGG
+
"3//<F9;(>G!""G+=(')5"/C;'(H%%3G4969=?0H=>%E2/1B@8@##(G;A,H@%7@26#0%<*(3-0H;=#9''F;'#0!7
@r3528
NTNGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCC
+
'(,F9":H7(2$*/@F$H&18@<1%-3+A+=%2=9<GGGD/!BC2
@r3529
ACATCTGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAA
+
,$$C/*=FC@A$ED78/@,!5--D#5%95FD3=EA!'D>#9
@r3530
GGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAATCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATT
+
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
@r3531
ATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACNTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGA
+
)H?&("C28C1A)&)6<,&<=097B#$/73D;C8?/43/B"335).A<,GF%707H#!%.>'>:!62.D;DB.5*H2/E=,<&"!/A5F=,2(;8D)'G/%7HCG*(<&>B8(@3&2.0$/';C3,9/
@r3532
CCGTGCCTTTTCCCGCGAGGTTGAAGAGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAAC
+
4+H=!.!)=$22+H5"B&'!H8,F82-C*/H7$BF786E8-0(<%G-#1EG;(1E&(!3&*G5,A!8?5=B?AB!:@?#9""8@5:B+F%,9HH-B3;$()4-6!:,0>(@A3)2$1HC(5B33G>?=,(EH%B*%!F1*
@r3533
AATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCGCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCAGCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTATGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATANCCATTGTTTCTTATNTAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATNCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTNCTTGGACGTCGCTGG
+
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
@r3534
NTGTTCCTTAAGGCGCTGTTCCGTGGCTTCCAGTTCTTCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTNAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTC
+
$%++#"**+'&!)*$%)!&$#%("*&%"$""*$!*))()$!&'$&%""%"&)+##'+&'('$+&"(!)%#*#!&&("()+'#!!()'%)'$"(&"&!+'("'++!%%!+*'!*#$(!)(*$!#($%*)$'")'#)%$%&()$)!*!+#+"(!"'$((")$#'!*$"+$&(!('!($)%")")")"!%(#'("#'%)('%+!!!'*(('&&&#!(*$#!%!(!"!'*)(
@r3535
ANANNAGTTAGCNTNCACNNTCGACATNATNNATATCTTCTTACTGGTTATGCANGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCAAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTNTGNTGACAAAAAATTAGCGCAAGAAGACAAAAANCACCTTGCGCTAATGCTCTGTTACAGGTCACTNATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTT
+
*!)#$'(%!%&(!)#&!&&'''$""&%#(#&!($+)&%($!%*"")&%+%&%$(&+'&$#*$&&#'&"&(&"#)%#+$'**%$&+)$!#!)&!##$'*$$!("#$*()+)&&'$*%""%(!&&'(+)('!(&!(!!##&+$&*+++"&*$)#"+")+%**($(*''*%!)'''+&!%%()'$""'""&"'+'*"+#$"+#(!$#+!#*"*'&'#)%")""$'*+#$)(&''*$"(%*&!+!"'*!(($%*!%"'&%$*)*'
@r3536
TTCAAACTCTGCGCTGAANTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTNTATCTGCCNCGACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCNCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAANGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGNCCNCCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGC
+
:0D40C/C72";)(";3F&'>%1;>B"2;C-$:05)AB:3*8<C><,43/>G"1DA>0<))@$8C<;%#*8%'6<(%'G<A6>/5(D0G+0A8'/(-'F6$%7B$!<1=.3'=67G:7+)E5EF+&425&7H"!=C9*9-E'?18HC:H*.9*03'11,!;'%DD*FDH!#0!H'%4,2)7..G@1,6E4G7!=G)''8GH$?70366,*H0%6E(D#!>*D'B-@,?04$<,)-@2H-0A5@5=,C7.9'('-4'4;?=4:<D8<(@><@'9B'</>G75,46"2,$E)<1%H@72=G4&)($@>BBA,%"+C2)"F8468G<?,87@ABCB""72%)#5H1-!/52%!7<+34."A0'*2('651'$00;@=
@r3537
GCGAAGGGAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCNGTCCGTTTTTTCGTCTCGTCGCTGGCAGCNTCCGGCCAGAGCACATCCTCANAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCN
+
(*$(*#'!(*+")"#"!'%*$++*'+%+$"%("')()'*""#$&+&+(+'"$#%'**+#)%%!&#%*'+&*##(#$!'$'%%%+"!!+(*#*%#('%$'''%""+"*###"'#**%+$!#+*(("#"$"*%!"(+&%$&(+&&$''#'"'''"*&&!+*$
@r3538
ANNGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACNGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCCTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGNCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACNGCGGCAGCCTTAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGANGACGTCCGGGAGACACTGCAGTCCCGNATGGACGCAACCCGCCAGATGCTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCNTGCAGGTNGTGCTGGATNCCGAGGCTNCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGANNACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGNGCGAATGACCAAAGAGACTCAATCAACAACTG
+
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
@r3539
CTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGGTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGNCTGCGCTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGCTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGNATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAG
+
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
@r3540
GAAATTGCCAGTATNCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCNCGCTG
+
::$$437/0@8$B897FHB3E,5#:F&B65&,7&*=2033$C:*=F3&49%/;F%@>!9%/0GGB-;(G:&'<6*(6/4C&7/H'*>+866:&!=@)9AH0C"0=>+4;4!F8(F.//?G3A0>9<
@r3541
NTTGCAAAATGGAATTTCGCCGCAGCNGCATGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCNTAAGCAGAATTTCTGTCATCACGGACAGCACGGAACGGGTGAAGCTGNGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCNTCAAAGGTCTGCGTGGCTGCACTTTTTACCTGNGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGNCTTTTTNNTCTCAGACNTGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCTCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGCTTGTACTCCAGCGTCTCATCTTTNTGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGGTCGCCNGCAGACACCTTCANGCTGGACGGTTTCGGCTTTTTGAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCNGCCGTTCGTA
+
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
@r3542
GAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACANTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAAT
+
B<9*&=(F7/6#E&D*5!H%..*H/)<0;>06C4"4.B$2"!/(7$>%&=#;+)?32B8"4B@#?C81#+,DDD'0E8%4#1=,&494(B3&0::(/#$('/"@/%D!HB(4!D04(*,1+.<D7H&/-D.>31-1=#(8A'%)>+C%BAE8#94G6<CE<A-$=/B#H$0)"-!>.>E7@(4<%-E?G":7"40#&'B-G3;..%G5A8#**)%+CB$7:(>5F,7&,9%-%H,D"$.CB@?=5-+=<7E#%7>==-E7:='">7)C?,.?;#C(:3@1-1/<,!:DF*"?
@r3543
AGTTNGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAANCCAGAATGCAGAATCACNGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACNCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGAGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATNTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAGTTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGNGGTGATAATGGTTGCATGTNCTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCA
+
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
@r3544
ACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCG
+
AD$$=4$@+5(07)-=B,'?:)-(!:7/,AA1H+*4#>19>.;>HD14C%91,!1=(:C1@@&)@7=/"G
@r3545
GCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGATCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGA
+
/:@;4D"(&BG3@G#"0'6+9H88!69A&?EBA5/$B,-%%$1C5+")((3F+C6)5&E$+<4"!A7F<9=;BH/4C#F*2-&A3@=?%,A5#9F&+3022,)F98/%3>.7DD081*<7AA>4--;4*::7CE4'21)A'BC1/*!;B!B*2!8>7*55$('$.=@;3"'3
@r3546
TTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAGACACCTAAGTTCTCACCGANTGTCTCAATATCCGGACGGNTAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGNAACCTCTT
+
9?,A<;8.BE4953-<D.DFH')2@.12(GH$"0@)#*G$2F#':+=<26-,9<'...H:76'C?C4'?,5*&.@,B*E**E8*HCG#+HE.5'GC1=-:=5A'))*30HED,'?#3GA,089(#D+,+=AH4B?8#A4#%D2<GD/;02%CB%E%'@H>(>C;F002:@8:#?!*?+!9,G9%1-DB<*$=.877-HED7>###4#EE$8"5H%$&?C@4'5G<)4>&<B<3+/)$0:3+-G/#C5>$D=:+5&,2D2$=80=""-8/8#DH!8E&'.G(0.,BBEB,C/+'$G*/982$'-5?@+,=$9;9.2%HGGC0EC1+%G#="&D.-)758G@C;.3D;7#<B=+**@/DB2#
@r3547
CAGGCAGAGTCTCNTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCNATCCGTACCTGATACCAGCCGTCGCCCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTG
+
<3,:9.0?7#(G'2*7,<@"AC<@4'+=C>>:75@36AH8.:<!0?F"A667F93C403:"!<C$'@D62?84A;.1E>C5$((,+64;-?<+'F77H1'1@'"%+65;%B9$6,7/2-=,!368>59!HF/$37=E.5-D-*07#(D>5D,,E:EG"0&#F80FA&--!7+6'746,0$A<F*.3:);6==#$"-*1$9+/89>+&(2+6.A6A>D28
@r3548
TGTTTAAACGCCGTGGTCAGCGGCACCGTCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACANGCACGCTGCCGCNTTTCAGGGATGAACGCAGCCCCTTTTTACGACGCCTNCGGCGCGAAAGGACAACNCGCAGCTTGATTACGGGC
+
?9/93B<4:82A"#19)G-'.;6'HD265F35!)>CF53.'($$>=F*67.7&7.(<>-.7$)EEEDC,;#<B*F1(1B/!/03+27)30A)9&E>A>-G>.9D0&<7:1,#:59&!5HBEDG>2A>6%0,9@HFH6*F%-@!;7$":1D0:F8.=/>4/<5H(-9),:/)'F5/F0493$<63"E9/(?*1,E3G'7B&?C2;"=/.%@$+CF$2-"/5;?/0"?9/=-!6='GEC8!4
@r3549
CACGCACTGACTGACAGACTGATTTGATGTGCAACCGACGACGACCAGCNGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTNGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTNTGCTCATACATCAATCTCTCTGACCGNTCCGCCCGCTTCTTTGAATTNTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTNCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCNACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACNTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTG
+
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
@r3550
ATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCNGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCA
+
4H4C409@+3?"8B<DE8;+%,/9)E!2302&09=-(4'F3&:,6*&#A8H4)%(E@3)>(H"G37)*>7$D60-)G:H=/7-#-;1B5)$+5-;;16&.<G=2%6,8()BD/3@(1AE4%5!.@H*C2#;C6!179D8>F#F12?G1H0'3>74;E8*D2G-=)-@"7"%*C.3@1"-FG4$@0/"'!2'%.10&A&"
@r3551
TTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTAT
+
<-B3<2?&9;=(;<'9A"B--BE!"(7&D$0-C8?2*>=!BFG*=7*!E11!&$
@r3552
GAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGGATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCANAAAGCATCGGGAATAACACCATGAAAAAANTGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTA
+
C.7)!E5;C>>:?+5=?!"4/';G4D)A!#E7(>'"@:?5>,3DD>.:3*5/D&7G8*!@9D4$=%;3/*EF61=,E?3:>')-/(24,$D1.!E185E0>@:91;@<+.;%1&=3638&BD16#+D4C>8,%.;*4.8<1#(CG#-1F1CD$$?!E@%9/+1'G?(6+*=73!=>,<2#&:7!%&3D+6*D<0?D$G87..G*<62:'(<@5*&,(4"=?,=7$H#&?*'6GF'@,$<C7DA$(>H"H2A=+9H$2D>GB.)?G9*<,F<23:2,'D(<0C3E;)(H#6B<"2',2;,;=F=+<A!A!4HH,DC'51;.63):!A%2E.,)>%:.$/)4313=#4>&@F@#9H2*>2,*-4@F&+8"F-6,9<"((<2"0:6!F=);=1FB)("
@r3553
CCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAAC
+
900.2A4/C%,*')=8C8?D*7B%'>4!FG:<<5799"E:11B&$47!:9-:G,$
@r3554
ACTCCCGGGTCTATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGTCAGCCCGCCGNAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGANTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGCACAGAACTGCACCATTCAGCTGAAAGCCANACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCNGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGCANGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGNA
+
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
@r3555
TATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCC
+
C,%@-?688>'0"G7BE=@&DF/;:C4%!<)4&BBD*@D%EG7%B9)
@r3556
NATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACAGCCATAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCT
+
!H<+<:8,26+/B>-3?HE.C3&?:EFB=,'BG&<HF":D+'#+/#?@1-4F"34:;)<G5*)9F"*6@*-?C>'#43AE,?$?A/H<2.;FB,E?<<@&*9C5;$"#&>87?9GGDD4A,&74-4.$6$%+DE054.6<7%2/"/'.A@-.A,4DA/G=70D$'=>F%,EB*65>8>;*.D@-?#(;(.(*""("(%0"A)>-B7'3)0(86A'$B3*:&"%@;#),@3$3/D,4H&1)HE',&>2'2%*;6G8"!AH&H7->?H@(-(44G%G:C&5;&'A.:D1+B+#A;=B931';G$
@r3557
GTAAGGGCCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCCGAACGGCAATCAGCATCGTTTNACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTACGCTGAGGTTATCCGTTCCC
+
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
@r3558
CTTTANTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTG
+
8:%(6F0-%&C#9>FBH@G51E,',0B55.-0G//);(H08%,HDG'E>G!F9(F)?#/B0C4B%;0#4)'+>>/)28<,.?C
@r3559
CGAAGAATGCGACACTGACGGCGCTGNCAGGGCTTTCCACGGCGAAAANTAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCA
+
$$*7:./0C&@AA8/B)%636>+<;ED?.:1('D;!@H<9F/77!:%/(E6A9?>FE3G"-!8"0&@@,10-!=%H!"+/5-%D-#&F;C@..-+(>#)@@"(&.A=>#HGBG7@8EG,"B064>DDB4C?5+<=?7)?"?4=!=*?#-B1G"2F99#''>"/+CEC0?2957)$4DEA@DA0?6)!6C/=..<$!;4F2GE0!%G071
@r3560
GNGTGGAATGAACAATGGAAGTCAACAAANAGCAGCTGGCTGACATNTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGNCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATNACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGANGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATACCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTTCAGCGGCGTTTTCCGGAACTGGAAAACCTACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATAACGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACACTTATCTGGTTGCCGACGGATGGTGATGACGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCNCGTGGTATGGCNAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGNCTTCTGGTGCCTGGGCGGTAAAGNGGCAAAAAACTACCGTGAAAAGTCGNTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACNCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCNTTGCGGTGAGGAGCAGTATCTTA
+
""+)(*"*'*$)(($"+(')"('("'*)'#$##)+$&(+&$#!$%**(%"(#+%+$)!%(*###%!(+*(#$"!+$&)*&'"$(+#(!!!#$"+#$+'#$!(&$((#()('+*##*%!%)$!"&)%(("$%%&))%'*!+&%%!+'$'(#$'#+*)#&#%+!*#%!+&)"&!(#%$'%"$"$**!&$$%'*"%"&#!%'++'!*$""#!&&(+*&(*+%!('*$#+'!&"!'&%"&(*&#!)+!"$#$#'!())+&("'%$$+&&"')!%('!##((&("*%!%#!$%%))&*!#'$%&(%+!&"'(%$#(&&+"")*%$**%%$(("*!"%")#)+&%$(!!$&#+'#))(+))$!+'#(&"'&$"(#&'"*'%#$+#%$&'*''*(%%!$"'(+%""!))!'%"#"#(#%$"(*%'&+&*!+%%!!)(!$$*#(*+#!!%)'))*")*('"%$)&"+'!((&(++*%(*$&'!("#!'+$$!!"("*))&"&++$#%$)&%##!%"*!$)($(*!$)*)('+('"&+("(#($!#''*+(""$("#!#(*#!%##!&)!++#('$(%+#*&!#&)%+(%*&&$)&!%'(+$"%)'')$%!"'"+!"("*#"$#+$#+"!&!**+("())&'$%)&'""+'+*+!&$'&&!%('"$!($)#&$')&"$"+#"+&$'*"%"$"%!+"'"+'$*'''$'()(%!!+")"$&%$"!*%!($!*++(#(##!&#!$'&(+)*%)'"%#'(&%)&'&(*#''(!''()+")&*$'"(#"+*+!#%$+&!&$&%"&!!&*#))%&+*()#$$!'%**#($")*#"$!)+("!("++!%)%#!'()$$$+("$()*#!+&)!(&&$(%+%('*!!*%%!"&!''%"''#')(++""('&+&&*$*%'%+*%))+!$$!''*$"&*+*$)($+$$)!$'+#"%!%&'##!'*!)$(#''%!#(*!#"$**%+##)+')"++$"(##&%'%+$+&!##"''(&+$*(*))($#+'"%%#*#"$("%&""#$(!&&'$'!+))*%"##%+()!$#($!$)'$!'*'+)+!&("'!$)*+"#+'%(#)*%(()*&(&"'"!('"%&$%*')$(#&'!!(''!%'%)&!&$!'%'()$*$'$*)##$*##*'"#+(((##))(%*#&#%")&"'+'&++("#(*#++%&+(%'&*)')#('(&'%*!*%"!+*"#$+#*'&(+$$+&%%)%$%("##!"*(!!*%&+&&#&#*()%!#$+!&'&%%"%('$%&""*!+!*'!(%#!+('&"#+
@r3561
TGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAAC
+
9-AC/(=76%7G'AB$18C&E-8!!<D1)1",+(FC<('F5C5!(G%E5(A:AG:'H8G$&-,C/(3@#B=/AB#??"?:GH<B,?(67:/;27?2BF>@4E*4G(6,+BF":"93&;A<<7;<,"):%@#=$84="-53C6>@.+*
@r3562
CCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCAT
+
3;;D=D%:&G36FD)/'6*=@,.4C-'.AC/55<&DE(5$;(2*E"6>7$46:<%1;%
@r3563
TGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACNGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGAAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACNGCGGAACTTATGAATCGTCCCCNGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGNGGNTGTGGACCAGCGCCACAATCNCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCG
+
0;H1/#F6C<,<GE/HA55:>6/4?+7#'*D>=/?$(&#*";2>:G9D&#6E3CA,@&%?9:0+F=3B5>%!$87:<"'4..8*>52;@BD,8D;C8&9E>7A?:C,9A!B#7?;FHA=2@0<)&.!%,+@-?<+E9AF9D5'""@14%-,**95'9@B/,&)C>:@*F)A:.4%5&79H+!8CC1<3?7(7(B+B!4180?5-!3-%"!>8.HG?"(,':>EF9@'<+=G?D&3((&1G3$$'=G".@F'';<#>*372DE8<!B7($;;&*2>F3$;*$5%>?=!%??.E33*>82%?2(9$:,.*'=B3?:?E7#A@#C)E7E0C>B<.9$/><=@,E3-/HD969#.G6=9$5061$E5/H3802#.'E(-2$:<!A:2%8E/??A(6*#4:82%/EGG@9/D2&G/A:F$D"/:5DC;+4-F-!872&(%HG#&=7.E9=*8GG,=3+H)'C#$$E)1#A/
@r3564
ATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTT
+
>3%G!/D8<,2AG9A.BE*80:*82"<2"+@10:A0'*+5AB1@H-5'*.$.@:
@r3565
CTGGGTATTTCCCGGCNTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGGATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGNCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAAC
+
%)2A(6!&")12G24-HB?"'EF$%0.GE=<"+51(-A#87HE/7')=!3%#);=&*/CH*8B7C$63"G'909+HBF"A1,D#=/H,/B=$6B34#355,F@;@',.=%=%2E:GGD5A51H-!*<*.!.F&3&9.>;69,<(?B03-FF:290=258?@98->81B"A@F/:;:)&9A1/D&;
@r3566
TGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCNTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCANCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGNGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGNCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGGTCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAAGAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGANCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTNCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAA
+
1#8+H,&$,?(<0=:/;4!)).G+:.<4>*72/%E8*+#)@?!0<E;2=)0F'/3.C6?D9D*9!4?7@A&%=",>='&,;+@$!*5$%F&+H>2,?;6*68$&*'),>"@=*H3&;:@$-F;(-9)4'>5;2+##+9-1282:9,3FH<EC?*H/.$D(2-?;C#!D3%H64*)1;,19HBH,HD<.6,:1:<H022'/9EHD".?69=36A8C"6;(E=45#FF;0/;5D6A++82('>5:)'A.77%=G)D(E@<D?.39+;#?8:#9'*%3&E$/$$$&-)A?-B7987<1:GGA1@*5(.DH;F9@(&%>890:"H-A;AF',79(*57#D32DD$!555D$,#9.B(=<//.:@D#C:3%@-7F,58=E@?F4&59,$'&HBH(*A&=8/5=3;>+6<04<,),E$C9A-&C41?A4.:)C**(+ED.0?!)'/;(-F/"@64!*'!$/>/2#C%C(E5*;*-HB3"#)@D':?!.*D,4!G0"91'%?0?)"2B3233.+;G$$'84G$F=4>/):F2)A1:D)/#2(#=42)B&&-,,H3)6:B&B6D@(B<+*15#A=B=%7<'8?1@0>0=:"2.BA)8A-317'6.;")6+4??!!+,G*@65(4F$+8;B/'&27&B>'#92+>H79*=@E(7*?#"2#',/?5;92<($E3*'1:)+"-9-:!83!H0(2;(($<&F2!-$,:(*G:C"+@#)5'7+(*-A!>@9'=#H?(#9F4$24.9B?'-@%>;%1
@r3567
NCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGANACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGC
+
#9@%4;=08/$5+:D*#:#6H:E=%%6)A@#G$(:=67%8C!?/(H63+EDC91$8)>C)*@=34;=-;'(H3<)935(.-6:.-#>!D&=80(4+,BB32=)+6H%=;+48*9F36<;/0H&1?#9%?-/'##-&;E;!<300*B-/3B;=930&"<.?3+B#
@r3568
CGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGC
+
=D76$)/>@C7'4$1$6"DC88-;<H#A8#G'!+@>;;*3%0*)A1G5FH"B?++)",+1*E=*1#H0'H@@++*85<89;"A)F;#<>187>&G.H7#EF;53:6.09D4B@GA"5
@r3569
TAAATTNTGGCTTAATGACTATATCCNATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCANATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAANATCGTCTTTGGTGGTTCCGCTCATGAGTGGCTCTATCTGAACGCG
+
E6#F+AH;$-.0:57>$7C+B2B#5H&(@%##H8GD&6"76@?<4G'1,/<4C+'H;)E6GE</!77'D0&D>6,H/(86;:$2%89)#AD5D?3+8?0H%/7960$G6G&*;!9..''"#%8?#5!?,9-H2<A2"3%->$/#!.96@'!A;32A<:&#@F1??CH.&G>F?AH933,3D@>;,2G-:G0.2
@r3570
GGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCG
+
4>90AE#;#"=,0)!!C/.A<09;D%:A>?$996@3A2=!H:-22'B?4F9EB&<#)597#'9&<.#</E=$8;E8%99'F&0@2#;8G36)H$"=49=@A=,6#31241?,-<&)8:B
@r3571
CTNNAATTCCGAGCTGGAGACNGCGGTGAAAGACNTGGGCNAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACANCACGATGGT
+
((!'$**##&(%)($'$%$''!&(#+%(*))'&&*'$*#*$%&%+'$*!'(&"*!!'&#+!%*!&#$%)!(!+$!))%)%&+)&%*%()&(!&*$(#$)%$$*!(""$(+%"'&)%$"(+(%&**(")*&%)"%%$(!**'#$'$+$"*)
@r3572
AGTACCGATATTGCACCCANATATTCCGGCTNGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGNTGAAGACCATC
+
@5?&F5.+&#5$!?;=F";=*:.H$+1/=#410+9#+?@#@+=4?6*2@)C@8&8E:A:G8%*1!.2@GE+2(8.?4GC$-828*!,4E
@r3573
AACGATTAGCTCTTCAGACTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAG
+
GD;-$D42C!25A51<&C%(-#8&2#0G3116:$5*>'$2:C5'#1C@>2/&.,;4
@r3574
AAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACANTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAANTCACTCCCGGGTATATGAAAGAGACGACCACTCCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGNTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTANCACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGG
+
88$@*B$(./*?8>+.>%'3.G&#(F53>=54593'@&B4$(87CG#@=(+@;(+9=(E/?1!62/,005/%F$%H<4'25..#8A2FF@C)26=GE+@E5(-"7746@(8,:5/&'8B:*HH;0;FF#/'BH&)CE6+92G3.6AAA:H>A46C+/*198,-'(DA8<B:/0+EE1/=>D#8<<DBFE'<G%HDF0<A7:0F4A(G%CC$E6AH:@5@"*)!>45A8!+6(05.-5%A82>.D>3B,%.7A+,"'3+H"D:&!5"7??@8+C@FF3&"#/:*F$+DE'6C!%?:=884@=$,245)?C0<(GE%A=DB9B7=*-(7#B9D80%&"+&)%C*;=E$5"&*;:>8#>143.::*)%$)#<EAH<%;$."/*;%68%<A!9BD);*-(;61);2DCH!BH$&2/3"3F(9--#$*/E,$)=&B<*(<,?E600'509//21(3D>+.7&@4''$2%$G-<:*%#4/((.<96=D1+E6;,
@r3575
ACGGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTT
+
'(!+**!+#&!)!*(+%$(")(!#!)*'!#+")!%(%#)%!****'#(*%"$$*$%%&##"%(++&&!++#$)+')))"$#**$$'!*"!)#'+'
@r3576
CCGGNTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTANGTCAGCCCGGAAAAGTGCATATC
+
>FBD,:0,8<.914A">'<GA(6--$$,E1(%D6%:;@EE+*7F=);*;;D70D@#&8$-1<:.D4!59H+,#/<5%;-F.+.$B4(:6#<-,
@r3577
GCNAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCNCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGANTCATCGCACCTGACATACATTAATTAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTNAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGNAGTAGCGCCAAAGG
+
B,,>C+6<H6."&(*C=0<#-7A#6;G%?=H:(5>:.55<E,/>@:A<(D,B5>@C83@.C$HG@('/<*9<*0:+%0=F??E8B-H?5*F<+<(*<6H'&2BE1E463(*B.)0AB.--46>E)99=28;,:7G';0673%9;BF,,3*F/G@#E!3'B4H6;'?G%)",C0;+A.>:19<<2A27=-F<,3+*'9)-@/E03!G7/-41H(997CHD()?='"!=!(%+D:D5,58"7@BG"7+?'/*=;4<$9G@?'>=?*82')@A#3:0%!'-D+@?!,>G*"3"-0-H6'D>!BB5-@F.,G=(9G?6F16A.-C.H=:0FD
@r3578
NTTTGGTTCATCAGTGCCGAATCACGCCNCAATTTACTGCGGCGACGGCGGGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGNCAGCGACGCACACACTCCCTCT
+
&64A6:(#"6(*0!E9.>929$.!H(F"&#;EE%-*6FBDCG@D!:8$71H"3%F-3'>->126A.8.:/3*=:"E1:;,4=?089!("(H8E9325B$BEC&2(2'F,)&%E4%=DGH+4<%<66D'"&=
@r3579
AGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGNTTCGGCACTGATGAACCAAAACAGCACAGCAGCGCATCGACCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTTTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAANCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCANACCACCGGGGTGGCTGTGGACCAGCGCCACAATNTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCG
+
ED0G9E"?3D8,13;51>%/>B1)=-7G>&=EDE4,G6?#)(9-9=D$)7C(@@$$)>H8B"@#@=E=16#;!+HE*B<'6DF8A<)4(EC:!,=AG?1<3D-6$";@BH6/'5B69!%1E)*DBA.<'&-3%.#"/(+9+$+06C1(H-/-E*,-8302H:(>,;06;<4H15!'*#1:H0B+,1F5!)C)85/'G4;!*@"%"B(7DEFA&:@187;*%,6-B"9/83'EG&-<;9CCC><+$:=E6:G&1,8#C8D!(*):F4C%78)@:'&#,"&A79"/:HG8"8'*==E9@31,C;9,=&*5(E*=!'%99)G1-%('%!8H.B=4;1/H.10$-C5%/A#$96B%%(8G6<D:F'B>420/=8=H=#!@HB98FD'B0@<;3A-H+68;4#63$47*@H?>>7B=HH4>/9?AB+9(<G$0%F81,":(!@D":,'-8D?-21E>H@=#%?6+4%-6";G.'A;9>ED
@r3580
ATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAATGCCTCGTCCATTT
+
7<9"/;)(842#CE/!HG*A27>*37=?D67))D+2@DDB,'>"'8&%$..@<5<0B8B577)-"47,1(
@r3581
NNNNNAATAACACCNACAGNGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGC
+
"#"$!")#')*%$#"($%!"*+()*)$('(&%%+%#$+($*"&%''$#&&#"+(&()"
@r3582
CTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATCTTGGCTCTGTCANCTGCATAACGCCAAAAAATATATT
+
'FF$;<B3:<3)&<?==+=%:"F@.%B0=@C!'7B5;=819HC"</0!&&;<3,'@!BG"!F!AA&F(3(*D%4?>-C2@(./(:8#/)>
@r3583
NATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGNTTGATAACAGGAGTCTTCCNAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGANGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCTTTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGNACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCNTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCNCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGNCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTAA
+
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
@r3584
CCGAGANNTTTTNCANGNTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCAT
+
()#(#'"!%%)'"%)(("+&'()*%'#!*&"$!+$$!$!(!*('$*"(()$)*$+#**$"%$*+#!&$$'&"'+!'#&!!*$(!)!)'*$+%$&+*""**"+%%(
@r3585
GGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTGATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTCCACCATTCAGCTGAAAGCCAGACGTAACAGNACCACGGTG
+
/967&;E1)2D9GF1D".CD'73<&"$%$4$),1<=53F5;885$05!DC@(%513+9$CA:D38H=:/HG3G)"?E@D)D,9<G+@F6=:FC/3E0H+'5#>+H+2;0=/-%<,7),<,?+:9!1"2H>EG:&1>*<C(<G:/.D-AE0(FH!E?%G/-"/H103%)!<D,B941=;C53/AA-F<BA'9+,,F!>'(F()?='&%E-8B+(;$=E(1:3C@,2-24H84#$7-#.H)G<89);2)5@"%1@"';+$:0+4,4!F:F'F--/+71;G>('7H>;.#FF(+9</(+A(!4HD@/5G-4/'6(7.:34);$;0$(G<?:(=G(@:!@-2D=C85*'B+9D1,:2@GF63#&G/
@r3586
GGNTGGNAGTNNGTTGGGGTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGANTACTAAACACAGTAGCCTGGATTTGTTCTNTCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTNGCAATGGCATACCTTGGCGGCAGATATANTGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGAGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGNTTATGACGTCATTGTAGGNGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTNAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCCNGCAATCGACCGTTGCAGCAATATTTGGGCTTCACTGCCGGGCGCTCGTTATGGTCAGTTCGAGCATAAGGCTGACNGCCTGATTGCATAATTCAAAGAAGCTGGCGGAACGGTTAGAGAGATTGATGTATGAGCAGAGTCACCGCGAATATCTCCGCTCTGG
+
)(#%$(#*(*%"%%#'"+&!)!#$$)"$#")'"&&'%''%&$+!*%$%&'"(+%()$(*'%"'+*"%''+##!#&#!(&&'!"+"#+*%%$$**!%*+(!'+"+$$("(#+$#*+"#'$%*$*)($*+(#!+)#+!#+$++%'"""#+")(#(++&)#*'!(*#)!#)'"$%)#&$&$$&#'(%!*$+%!+(&*&#'+(&#*%)(&+)&*+*)'!)'%"*!&%#&'&$&&#'&($(#!)$*!($&%&'**+**$(!))#(')"*#+"+*&&#(+)$+"#%#(#!*+*'((*"(!$'+%()$)'#)(+)*##%*!)))#))+%&&(!")*!&#&((!""&$(%("*)+#%&#!%!"+$"'!#*&#%)**$+#(*#!("&))&()+)+*%)*$%))#*&'!+')$)#'!(#$(!"$+&#""&*!("#!#*&++)(*$%#")%+#"!%+$"!*"*)#%#$#$$)$")''#'%#((!(&%!('%*""')&!$!)("$'*#&"++(!+'%(#"$$%)(%+''($(+"(&$!(#*&(+)##&!(($+&!(($'"%"&)$'(()#$#&*)'+%')#"&#*)!#*(*!*))%"!+'"&!&"##**+!+(')!+$'('"*#'")$&#('(#%+)*"+)')%)'*"*"$+*("%"$%!"++$"(((&!#'%#*((*('"'$"$%%#)*(#+'("**"%%(((!$"*+&"#'%#*&*"!%&&+)!*"('($&&%*(%'&&&&#)"#*)%$+')#$"$&'$&(%&+%%!#"%%%!)%$#$%'+&''&+%"**'+)**##"#(*"!)+#"&#$((#$&!)"("%+%%#)'*+%"*(%&!(#+#)*!$#$'"$)%$$$&$'&$$"!#$("&*$&'''#$#(*"+#'!$&'%"*#)#)!&+"!)'(")"''&&*!$)(!%"*+)+%+&+&*!!!+$)!#+!($!&*$"#)#(%*''++*(#%&(%*"+++&+"+%"+!%$')#'"'$$
@r3587
GGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGANANCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTNTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCGAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCGAGCAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATTGCGGT
+
,"FB79A604%"7;/B8!6=D<8":@E!='5!2G,.C!AF*+F%4;**DH+?A+C$!=;0&+B.;/*9H917G5:#B;!;>&/%90%B49'>8$E5*<B7<-0='E.021(.#G4=/6FG/=H392"/2/2"*,<B"A9%G5>*H-0../0;1D'2,8.?'1)GA:?"49$=H.-<F3"FA&+B56*2<9104>3FC4>9(8;EF=)=A1&!9?-G6H#B-!B.@DD7'-@9590B&!C;&89>&3B9**1"G@75G0D,<@)+70>*7<!B2</E)#386-8%9/,A#??H9$H,=:81G43$.(1D)#1D:A2/=-5%#$=D>,?'8A><7%88$??,!%8&?0?>3C:$%F"8(7..17E@",-7>4"95.2G3"G3<%C@F2$#83C0<C4G+8>!;FB9<,5?;4F36##"5')E0>&!9#6=(67>D#7A)1C/376E;/0:$,9?D3C#0+A223H&9D*2D*'(/-G=2EC18D+5!@#/0AC
@r3588
GGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCTCGCATTGNGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAA
+
C&)3E'218F';D-?)?G@72H/8H023&@'#E:AA=$(()8D=$=@:,D*?68DBH/D=%:2E009<)),/F1';./F;.!!-C5'!!1D4&-#G0@#!31:-5*0<421?!56:<8G2,9'G/,'*).1.C79>.+<;40H&>C3"03&FG27*3<<&$&3.EA0&82#
@r3589
TGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAANAGAGAAGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGANAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTNCATTACTCACTTCNCCACTTTTTTGCAGA
+
,G4BG8=,74%69)),7*009HC9%)==65/0&;/")A#(>B/(5#4%=H*D;8'<)":C>/=B/4=?C"D;#%>><*63!2,@B0G"4(H"-@HA90:32-++0.CE<2D4)9E<'4=6H7BH<=#08,)3%!+,FB9!+5+*:%G:,%5;$'?D&$?$.%/6?FAB<>4#*C6<F2894&<--!08?"CA$
@r3590
CCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTG
+
(&7$;)(?A.&/7H18>#</,CH;'7"40E<;B4G*FF3D=E3;A.>#6/:CB;=5,?G">"3$,AA)'0>A+
@r3591
TGCTGACCCAGCCACGGAACACATCNACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTNCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGNGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCANACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGT
+
,<*%?56,0?F8&6&!::H'08@-?1:$>3)5.-/%+H#@>!3&<;!(4380;"C8)E%'#7:,84":H-3"8,!-(@H>F+:-8&(,/40G,'F)&>B6F&B:6D/A<,9>'C>G7,)E*C.@&A),?03//1F/";0$/@2CC?%=874*>9.E!/72G<:*=@B/FGE;H'AD7,*>0'G'5'$!,(+%+5=D?C3D5,1<")G3)E:?@HH,@%G"A"27@$C.D/!::#.$?CHH;5+E<"&*<??H$@>,#':B*$./A&)3@4C;/;F@$.5:23H:D>:F2023+=))&-016*28C%-:?9<#B=3G/<66,H)C*3/3'>7
@r3592
GGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCNACAGTTAAAGGAACCAGCACACAGGGTNTTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGNCCGGTACAGCCGTGANTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTNATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATA
+
;).*%"H4;3!)$,?"13E8;DDF/;*1&'/6*$;$+16%&!#)<%H'H:7/H@28.G(F3,C5&+.H?A:5!-!2#.!<220C+)&#CC)=496BH-:6$"9!F"++<2+CA)!.?/03/'?08-;-/5F''<E0;GC0>=B"A@<0735F>$)(3AD%(HG#),4":6*>D,1%.$%8)/&;H?(-4-2C02,*+B@626*?#D$D@991+D=4:C.EG8/?FD+;!0=;47BD/&$6A&G00G-&A1!.@1,'2$H-$@.?7=E)DD6CA,79*>'&,E-%8/!)BDA;@2:43><+EH)"#13>B7@+E0'("+:HA#GB/*AG181,;%%=3&:!"9=@(C991EB:)34(3:=4D6=+A!-C?0F!)B9,-=)><4($)05=2?F(!3D;->2H>&3.H%2#+;@"A/
@r3593
GGATTTCGTTCACTTCGTTTTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGGTGCCAGTAACTNGCTGAACACACCGTTGAGGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTGCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACNATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCAGGNCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGNATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCAGGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGNTTCACCACAGAAAGGNCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAG
+
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
@r3594
NCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCA
+
$GB($52;8:'D)B1&%<:->?<),+)'H87/4F"<A.5G33G!H;C%?:A&>6B41+#;F33'G5%9?E9H..4+*04$E/F*;C95,'19G68#<$.6<5;'B#/7
@r3595
CTGCGCCGTTAACCCGGANGTGCTGACGTCCCGCCCGGCAATCCGTACCTGA
+
:D*#B8H@3+C>>:E&$H"1&76(8,1!($*B2:F3>7-F8GHD6B734D?-
@r3596
NCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTTAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTNGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTNTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCA
+
'84G61C<$&C42)"@:)3;E09-G;>8D,CC(')A.9B*D/($6;#"'=3?/&4!.F2=B?$9!4&,G@&956/-%4!$@2;GC.=,;+B!@&)E'B"D'0=""AH#7AFF>-D3'4-D('!"4A&086E4B7=>B&1F-*;(5**8&.'A%;(F711CB?D@?34C;$F<181=-%;CB<<2A5:/*/?B3419#&0):024H#6EC/D,%0C%4;(-:+G)>#,?/'#*)FEB>48)=%;)ADE53(!'5:623B&7<!9:9
@r3597
GCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGGGGCAAAAAACTACCGTGAAAAGTCGGNGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGANATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTTCATCCGTGGCTCCACGCCAAACGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTG
+
B9!73/B(&7!'#%7<!)B95@C>"."D&?F(.&19;810$:*6FE*)9)G3,;/;CH2"4F6*A.==>EGGH2GC(F'4BB3<392B3#+.2CH/A,7(C<1,"GG3#0F@!#A"+,;.G<#E//C6E./),0)+8G2A;>A0$?B9"*D>"-G9.>*D')?0.3$"@:1-3'0F=*/@-1%67+987AD=%,*>D14..;#;%7A%3;7/>'C%+G&F:8+/+D=46&=!1'9"#9+"3F."<GF*'+"*D4=AH16('@?&1#,BDD9BE=9(:9=4C.+D1;>!D?//'@A
@r3598
GTCNTNCNATGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTNTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAACCGTAAAACCTTCGTAAACAGCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGNCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTNACCTGACCGCCGGTATCGACTNCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCANATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCGATAAAACCTATACCCGCCGGAATGGTGCAGAGATGTC
+
!#(%"!)$"#&+#*"+%*+$"'++'$#&'**%!++%#$#+**!+'%'$&&*)"(*')!'+"%!())()!$%)#*%&")&"*"#$'#++(+('%)(%!(*+!$&+*#%$+!%###)+(+$'#+&(('&%%#+$#&+%&*#"#*$'*##+(+#!!"+!''**%(+)!&)&"%$#(+!#$!*!#*$(''(&(#"%*+%"+%#+'!$'*#*&$'""%$"&%((($)!*"!*)#!()+')"#+!!')#))"!!*%*)$$#$$&!#&'#!)$(&)"&%%&'#*)*"+$%"%"(#+!**+&%!!$%!$'()&%&"*#)$+"!+"+!(+!&#"!&$&(!*+#*&&)!&##!$+%%("#'&*"$%)!#&%'#'%%!'"#)"#$)#)%**%*!!**!$"(&#*')!!**&%)(+'#%$#+'("#)'&+("#)"!*)'*%$!+*#%'&$)"(!%(
@r3599
TTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTGCTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCNGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGNTTGATTTCCACGGNTAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGNCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGNACCATGCAACAAACTGCCCGGGTGATAGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCA
+
?CCA,?!$62=?G+4%E,!0"+)&"6:!:4B>G=39)=@C>AFF:*%&4,F*8H8-!!0*DE5'+2G'A!9*"9,*BF*$E(#?F!A0;%)&!E<%4-1*GHD&FEBD,!@0$:;3=$28#5!//:%<BDG6,,G1$8:8.BC.-%%,4.@"1C)8!,6G%(=1.%0"C8-2"76$@/>?"*A#+<F@>$:G=@2/!9G)/7>*<0=G?!!9-C2H;EB+6@$0+:<(,7-->(!?=):4#$!?>A1C9!"F?<2*A$6@('*%DB>@G6/"'H0?%&0:)+D4E2,/$+#1B!77.?*A/=<G1)88H,<-)-F:FG.4G@'F(%DD6A2<F/+,'71>=D$66>9*423:!",/02<.395C','&@#G!601'>+&?.1F?542
@r3600
GGCATCAGAGCTGATGNACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGAATTGCAAATACCGGAACATCTCNGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGCACTAGCCTGCAAAGATGAGGAGCGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTNTTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGNCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAANCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTNTGGCGAGACAGCGACGAAGTATCACCGACATANTCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAGAACCTTCAACTACACGGCTCACCTGTGGGAANTGCGGTGGCTAAGACGTCG
+
+"($"$*###"!")(("$($*$")%+(+(%+)!(&""'*'$&#&&)"(!$**$!)!($*!%$#*"*(&"$")+*+!)'#+*#'$!#&+#$'$(!!%"&+&('%+**$*$*%)!!'&#'(**"#!)*%"")*"+!%&)"#')($%+(#(*('*&!*'&(%$*+$&(#+"%'"&*""")"!)&)&)+++%'&"*))($&%*)*%*#(&!"+)"((""!!$%$$#)+%#"*%!((*(+"*'')')*%$+%')&&$##*!%$&')$*#+'"%"!!!*+%)!$(%$!$&*)'&!&!&)+#&)*&*)*!)#$*)+*&"('#*($$*#*%+&')*!+)&(#!'+"*!)!"($)*(#!$")!*"*!&!())%(&*$)*'#&()+"!'%$)")!'&!#&#&$(''"#($*&!*))%&&#"&+$$#*+'#!*)"&#$'#!+&(*)"###!($#&$(+))&*'(!&#*(#("*"&"!(+!&&+($"!'&)$)%'!)%!'!"%)!%!((!)$$(+"&"('%%+#'$!+#&)!'"%+#+&+')*!%#&%)+'+*(!%%$()"*')"'!%''"+#&"$%%'!&)+!*+$$#$$#)!!&!(!'(%$#%'')%##&!&&&(("'&"'!%$$$))&#*)(!&"()$#()%')#+!'))(!*)'!&!!)(*!+""&"$&)+*%*+)'*#%"$')*)*$'*!##$)")"**+&(''##$#''#**'"'!()!$!!#+#$+)*)!&&*""$'%##""($'*'#*(%)!($*&)$+%#*!"'
@r3601
GTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCNCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCNACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGAGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGNCATCACCATCCGTCNGCAACCAGATCAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGNAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAACGCCCTTCCTGGTATGCGGATTCTTNCGGGAGATAGTNATTAGCATCCG
+
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
@r3602
AGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCNTCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTNANGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTAACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGT
+
B9)3>GE)29,7*2-,->>#1<(C>2*)>>>+4C&6(C-C$@,.954$AE2A73B0#8,9E1(9'.-2@#E#)%=@('F??E-.B9D*,3"%%%05'"2/832@28$7,F7;H=@%DD3$4/+!!G,2&=9<2C;;2!D5&*=>('B$,D9=#F.6DB(/:G??''/;H.+(C1>%<3G%36'?>:-06@7+#4*1)BC5A8/7%#49)@!%/2")5#>7C@,24HE919?"'1$A>D%"/')G'37-ED)0D3G4A/3"!=0%1&0/-@->-9**!H$&!$:*4!9?&6%<EA%:"6:>02-8H-/5;:+:94$1;+9B!:75&D9#BH!F9+$0;)69#8*+490,4F?0
@r3603
ATCGCACCTGACATACATTAATAAACATTAACAATATTAAATTTCAACTCATTGTTTAG
+
!(&(+()$+)(*$%$+*"#'(%*(%$'###'!(!'(*'"($(!))(($##$$$%!&!"(
@r3604
TATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGG
+
=B'$>()CC8G$H17=D4F./%E;1EG("55G)1'5$44/<E%@
@r3605
TTACCNCNCGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGATGAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATTTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTAGAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGA
+
($)&%"(!!+$&"!!+$"!')'"(%"+&+'(($"&+$'*&+***"!$#!'&+*)*$(%)#$$&""!&)"&)"$(**(%'$''"&+)&++(**(*&##+*')*'%+'+%!&&$"($%)"$+')%*%$("*!("'$*&$("$&%#%+!!%'((*(("##!"!$!"#'*$$$($'+'!"+!#$#'%)$%()&('+&&$&"&#"&%$*#*'!$$&&#*$)!"&"'$'!$*'$#")'&(#'#&"%%'"$)+$*%&*)!%"&+(+%*(!&&*%$&&*%)+$$
@r3606
CGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATN
+
(3?;A%";?;'C$#:&&=<,,"')B/9+64<,*5B8*,''5F)359'.-D&1C3AH4=>'E'0##1->)#
@r3607
ATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGAACGGAAA
+
*6G..(E'E@<<<);D0H6<B(1CF-$*"@&?E'D<>0#4?/(B32604D3GF0/:@(80C'47%-,A#+HD&@)@7'G:&E)<)D-C,
@r3608
CCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCNTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGC
+
$H3G4*4(6(*?4@'//D>*<$><F1.'))*;A>=/11-"?+<-E0<?&?=4!1@$72'498+>@#/<44F&5:G6:8*9*'G.>16E@=-)$3.?6%D2=#@EG.(BF/(?,6;;B%+6F$8=1(6>5+7283)A-):5"#(15GC-7+*E<%-GA29@2.G9!'*-4A@FF50&#=!EB!,94=8D"<,/-@GG>3@'A*=E.41,$-!(5:!(,5%'D4<7!6;7(:-G-B;(/:A:=&4>(-A(CB75G2-69::DD("=E=!7D=--G2E(#E8.:*1<E?($)5,((<:G*-
@r3609
ATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGNGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTNAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATG
+
(;*.BC436(>;8'?2//E!/%7"+EH%*:19";7H-D+)$7!4<6C:;8.B?!F8="0FE>DE)!77-&6!"G58!?A@:*%@%:9$954C('A7(16.07+&,1>;H*@?4*?*-4C""=+/..()?G
@r3610
AGCTGCGCCGGGAGGTTGAAGACCTGCGGCAGGCCAGCGAGNCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGNGCAGGCCGACGNAAAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTATGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTNTTCTCGACGGGCTCCCCCTGGCGGTGCAGCNGCGTTTTCCGGAAC
+
+4.2%%:;@)7!'!,34-"-F<B;BE'3='+752;='",%7%C<0F82!.1)-H95A61/??(=4C'"F!00/9*:H))&A.1D$HH&F1/)((#;06,73<-;D5:,">EB$#$78<<3A;!.)+B-)8)<D,2!?9.**D,($A@$*)4/9-%0F$9F.0?#212287H5$5E.>D77D0#5/7!2E.'1$AB"339=D/E/4<?$C!5:>*E6(>">F;?=%F&GB'@C3%.-8>*#-"9$0=
@r3611
GACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAANTTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCCGACATCATATG
+
1:F<63,.HF="39F.64<)<-D'$&!,&6,+<F62E?'"?45<9$8.$!?/7.0*H4G8-.=%/A0:#@D&022DBEG9--A-(F*%:@0"&C/6>4$)%F/?B<E65&$83G7D(!1392<
@r3612
AAAGGCAGGTGGGCNAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTTAGCATTTGCTATCTCCTTTTCCGCCNNTACATTCCTGGTGTTTCTCTTTCAGCTCATAGAGATGGTCTTGGGGCGACATNGTCATTATATGCAGGAACCATGNTTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGNTTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTNCTGCGGGTNATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCA
+
D8A)G95&+%,55-!)--4#=/8,(($!,<-E>:'4(3')3-")<D2G=B;,-$?9?7A$,EEC>*:3C$8(9B2G(2-&9=!:+6%:1G1@>:B5(,#D?AA/!C3,=,36;->>36;07#005)5/HG36:CGC:C:&!FC"@'-=&H7+E:4<C&C8H:FD3>'A#-),)7>>!.",08;F3F756$1B2#10H@>(D5&@@-1>H'#:)D=#2-@#DH>4<39691;.)7-4??"C9%3:C(;A45/G"664"@@G)0B'73!1)$<D1,@%>B381"0?H>%;2FA(.:8<A;8"!6:AA@AH:0**4/;3'C.7>#F+62.C=+G>):E<*@5B8&:5*&'864#B<F$.DE)*-$>D(8H0,74*F3<(8,>!*F"#-07A=@
@r3613
GAGTAACANAAAAACAACAGNATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTGGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGACGNTGTGGGCGNTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGANTGGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACNCCCGGCGGCAACCGAGCGTTCTGNACAAATCCAGATGGAGTTCTGAGGTCATTACGGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGC
+
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
@r3614
TTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGANTGCCACATTNGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGGCAC
+
0@/+-,G>0"/"+AF9A/BB)E8F(4?D95-%5,&'F7=(8F3&83AA:',.D"$;-#."9!G&@$<!/1/-*$)E@30"&A9#F12%G89&$3!A$(.6A'31!C'--/E0,+3!6$<5=5H4$@*6E=E--<"!F$($&@FE?:EE$HG=F!)4@*1!GC(,C4E?H@"D,*F2
@r3615
GGGAGNGACAGNCNTCCGNNNGAGNNGCNAGCTTCACGCTGGCGTGGATGCCCGGAGNGCAGGCGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCGTATAAAATCCGCTTCCCGAACGGCANGNTCGATGTGTTCCGTGNCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGGTCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTNGATGGCAGAAGATGGCAGCACGGTAACAGCGGCANCCGGCAAGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCATGGCCTTCCAGCCGGAGGGCGTAACCGACAAGACCTTTCGTGCNGTGNCTGCGGANAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGNTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGNCAGTTATTCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTNAATGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGNATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCNACCGGAAGTTTACTGTGGAAGACGCCATCNGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCANAACCAACCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAANTTCTCATGCTGAAAACGTGGTGTACCGGCTGNCNGGTATGTATGAGTTTGTGGTGAATAATGCNCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGNTGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTANAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCNGACGTACACCGTGCTCAGCCTGTTTTTCAGCGANCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGCTGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATT
+
*#!#&!'"(*'%"'(*#%!'"##"("#$+'#(++##+('""#+"++#%("(&"(()'&)*++(&&*#"+#)$*)!(+*"'()*&)!**++(!!+&$!)')))%%'"&'($#$&"(*$!+"&'(!*#&$+!'")&**"#*&!")$)#+%+#"$&$$))&!!("""))%#"*&*%'"*%""!#)+%+&#(#%)(#(*'$"$&"'&$*$)(*(!&'*'")$*(*&))$$$%(&)'++)+)!'$'$%($*!)$$$+$#+$*!#")(%!+(&&$!(#*$)$'$*&&$*#$#%#)%($)%#+%!$&(+$)&("$!*&!*"*')()*'*$&!&)&%$"'$$&+$*'$$'!%+&"($!%)!&*#+(&"(%")*'!%('!'&"$%)%#%$")'#()+)%##!#&#%!$+#$'(+&%"!&$'!!!*%*+!+$*("%(+)!*!"(+)%*+"&&!*''%&%$"(*"%*$$(*)#'#!*''!!$&!#""%#))$&)#)#*+***&+##)!''%$)()'!%*%%%)("#+('&%+"#*%!+$''$)%&'*"#**#$+!&&''"&!&+)'"++(%$#!)'%#%(#("'%&"'+'!&$$)$#(**%%%)&)'"*''$*$&*!%'!$#++'+#'&"$##)#+'#$#)$+')%%")(*%"$()%"$&'"''&%"$(+)&(%&&+$#!#!%*(*)#+)(#%'$*#"(+#$#"*&%!'"!)'")!)%#"*&&(%'%#"'("$")*%'"$*"$#$)$'$**#%*$"+(++&%$$!)$!&$%"!&"!%*&%(%%%'"$)%#*)''!&'$*!(#!"(!&(%"&("%&**!%'"+)$*+(%!'+#+%+"&+*&%$$+$"$$"%#'")'+%!"%&(#$#'%("*+#+'$")$"*%)!%$")+("''&'"#"$)%*+**$)'**))$++%*!%%*))*!!'$+$*((+*'##!"(%#)'!'"%(*#""(%+(!%)##+!(""!)!"'*#*")#+'%")&*&$$$((&&++&!%'(+)&+#"($&+#''"##&&#"!"%%+"$!#)%*%#'**'!$%%$#"!"")'!$&%&!)*#*&'+!*(*!"+#((&!+#(&#)&)""#+$)!&$+%*!#%)(&#!*()(+"&%'"!*#&##"!)*+*(%"*#!!)*$*('&"(&$#*(%&')$*''''!%$##)("$$+*%)'"$(%&)+%+"*(#'%$)!*&'%'""%)'*()+"!!+%*'+!%%**(!)!*"%)%($#+*&+#*'#'((&!+)+$&)%'$+)"%&+!")#+''(+)')"#+!'%#&"!%)!!'#&(%'*"&%#'"*+$%(!()##*%##*&!!($'$'&&+'*))!!$&"$%()+!&#$"#$!+"#$(&')'#)*&$%)"*$($#+(#"""$#!)#%"%#(**&"(*+'&!&!*(++"*#+(''#)'($)+#)'"&#&#+"(&&%)+*'"##')+$!#$!"!(&%+*+*$*'*'$
@r3616
GNTAGTTACTAACGGGTCTTGTTCGANTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAG
+
*!H?0&%4&%%6'+B$#:G!F78-,4-;)E!76#6&#<8@>)@C@;5"H;A:5H:H2<6?A5('HF&,"%@ACE1;#:/H;#6:@1&H6/1)78H=EC(D2$=D>"D&(">B*;"*F75>.H..FG=7="$$'=F!3B8,8$E761>04H9D!++A@;":316?%AF5H&,;2H<9/#C>=+74"'"-**7=&+=<@4*-HC.@>4#1!*7;9(8H!5-F!"D!'G=!@D*4E-(#'26
@r3617
GTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGAC
+
=A2**HH(=*B0G,6*F$0G?>/1B@!6=1==.?@0"B-&(E7$H75$,+@F4"*45F+""@94=7((1")5%:A>/3:E0-D<&:FF=*,.A=(97$G><E=4+G1($,82GC(-=HD",@467.+@:6"HG>%6%5!-H8@'B4%!<<8;3F09C/0B:5F,,)8!#@,0+=H1A,(?>=76!830')*C.<':$A-H9&3,+H3%;)@('>E@38A9HC?(554#7=;%H:+F6G.;:@"9,G$)%1$/>F<=$5=:40?<3E%/%G:+G;;&:-49'%02:9'C,903:?'$3G6'DF),G.;?H%+@4++4=A4!;)H6A(F!&B)92:9*%#HC-HFD
@r3618
TCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTNGACATGCCAGCGGGTCGGGGAAACGTNATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGNGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTTGGCATCAGCGTGGTCTGAGTGTGTTACAGTGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGNACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTACGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTCGTTGTCGGGCTGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTNGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTNAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAANCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACNACTGCCAGGGACGAAAGTGCAATGCGGCATANCTCAGTGGCGTGGAGTGCAGGTATACA
+
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
@r3619
ACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACNGGATTATTTCACCCTCAGAGAGAGGCTGATCANTATGCAAAAATAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTNCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGG
+
C$?6@*3:1-AF<(/2=;*76C&47-A""F;'$(;8/BG.6D*<:3A=1/FC&4&-%:;5E<6BD#)<.A"F?D?H(>:C-B;@H3.)G2C40E6C='/.7AF74=C)?6@%.392-:6;5*!?BE:?,@<+CB:?0%D#;D.3E>=8=5190D+$(F$,.D9)E$8*H88---4*-!F38,/..5CHA;G('@DC9,'C=D:>/DH%A4;>;+3#A:$E)(.B,6F$6*#"3+4;5#"65$/,3F:D69<%GC&,C4**EB50DD#23D98"69$AD=3?*2%E@B++&=A27!3'D==9@"%;3
@r3620
NTATGTTGCCATCCGTGGCAATCATGCTGCTNACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCNTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTAGGTAAGGTTTGGGATTNGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCNTCCTTGAATAGCCGACGCCTNTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTAGCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCANTAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTNAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTNCATCAGATAGTNGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTA
+
%D0>'7-A5%1#-*GFB(9;=$2GH)*;57HA.2.F&+),904<3!(#2>@->G39G/&?%@DAD:+=("E1H'<D9??1!EC-:@*;:=(<&A@=9>,&'"&=!@.+;1-+)>7H?2$&#2FC-?GA+';"#C8#$"!;/G/!/0HF<(49$-B!BD70;;0F25780);?EF&5(2*@0C.(!14.5&0C:@?6*%#6-E08B.1;$!/D,#'7%>7*&*;=(HD&,31%9(7;":4$-3')E)H8(5=7537-3>G21&(0(58/B=+#E?2?BAGDD.!/<A;;H:85H5E''!';84/,+>-2A29EE(18E+*!51$H$0FG(5&%!30/7682,FH$%&@?@H-//<.,-1DF@B@,,-.>D12E/4.32EGEGA<F.$$2$,?C@!>2:DG.(4)/@@:0E,-7)>>1C;9728%$F=16C>1"DD*(8FB9((17(>G)%E>'85(5=1D<3A?4.C&!==?;/=#0')?4$$3%B%"@##3A
@r3621
NTTATTTCGCTTGAATTTGAATCNATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAANGTTATTGAAAAATGGAAAAATNATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCNTGGCATACAACTAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTAT
+
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
@r3622
AGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTNTCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAAC
+
G*)>.F3@)@;#$C9GC6E6EF,(=*%!635&F9>!A*,A4!837"=1F72181F7)+>G!,@+E:,E:=3"7B4:DF,.004&5!9;58B5;G>2?>9$:G641C931C'2=*>0*',(?=/$3@BF8(&7%!F(B#'DH7FB;$9G96F7<B9&,<.$#7"+%<%%57D(;%AD"+:(H3=)=*@6<7)2$@?35.("C8HAB$3%8;>G,'<BH.:<;;2*:;8*.201CA5E-D(&7$?0@A2(:E,="EB2>G8ED7;(1>C+A4)D9"5,865#H$')'+'FB*<.%-)FC(D#&,#",</3&-99G3D*E#@/"C(1A2.:#+-!&/,/?*/1%<5B2D;;/-<)!(),D"EC7)3-%>,6/;:+10%4B9&?4)"298:=B%2>/9
@r3623
TTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCNGGTGGTAAGCACTTCCTGCTCAATCTGTT
+
H"4=.HG@40;A2#'-D"2**/*1;0??/:72,C(,A0;1+=9A,%B#*H>E(H<%AF)'E>A9<03@C@A/?H/?74:F=>?$9H-#F767&6/:G.H:G098$E50A",;C$>G),"HH-)0#+F@,7&>*4D=F<'+,#38?H;2;4"@A;)72<'&'-E/'>+7"3F/GE/.A+4FF<5)F.*AF$;9
@r3624
TTTTCCGAGAACNAGAACTCAAACTGTACCGTCGGGTCATAAGCGGCAAGANNCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCNCTGCCGTCGTCCGCTGTAACGGTC
+
F'9H*3E+%(!3$"-292>G5=C-0"&F0,D@@=--:DB=:*8%9%-$8?BG'>!FH;C0)5.57H,3H##+)#7)47<F:EA$7+#9'8B(H&2H&C;1'4,#(2C#4,G2=;"60/9/G?></7-*(+D.F&+EB=#:4AE=A*&3?91@%"-!93'E0(D9(&@;C?&7*6$@#D19$FGF9?0%.--@"G.%HH415+'(HDE)-?A"H9F#)A(D2HE-+F"/(*F%'@=GE96C:>++'38(6C-"!+7F04C"#;1):#-C5*%D)?;:
@r3625
ACNNCGGCATTCCTGAAANNTNAAGCGCNCTTTNCNAGGNAACCTCACCACGCGGCGCACGATGGCCTCTTCCAGCCAGCACAGAAANATCAGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGNAAAGCTGCTCATACG
+
(!!*"&*&#$"(')*!)($(#!&()"%#$&(*!%%%##$'()$$+""##$'(!'%+'&(&'+%+++)!%!()&(!"**&"*#*+&"&%)!$&$!"")%%$'&#%#&"&**'*(&%*&*#%$)'&!(')"(#(&"$#(&#%$$+$#+)+$*++$"(')%$$!*&&*"+("$&!#%%*!'(()&(("'+&%%*%*$%&'+(#%(%"#%"&+(&($#)
@r3626
NGTGCTGTTAACAAGTTCATCAGCNAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATA
+
"+=$<335<:/>978.D7=:D./0(@8-//,!H!&$9<)3*#'77B!:+)$9GC-1>:H&+90A0E"=5/72?B30HH=GD%#1E5)F=D#?3;60(@09H:)FC
@r3627
NGTATGGNCANAGGAACGTGTCCGCACCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCNGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCT
+
"$(&'&)%)($)++#!+""+'&'*+'&&)!+&*#!$#("#&!"$')**&!(*%+*#!*"#"++#&#&(")!+"!$)+*'+#)!((##"*$')"%#+"&'%%$(%$"*$'!*)$*)"+!(!'%$"+!#%$&#('(!#"$))'!!$'%')$)#"+!)"#*%&"'*%!!$$#((#$)"%$$!$+*++#!(!)''#)($#*#%)#')"")$"+(&'#+"!#%('"
@r3628
TGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCNGTAAAGTCCAGCTCNTGCTGGCCGATGACGCAGGCATTATGCTCNCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGTATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCATCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCA
+
!,C5'5!.&D-EH:A>H%B;*B7$C**(;396%#*446#.!9B@9&E5G?5D!@#C(;"EA3:CE?88+3--A8*19$=94-;9A+B#;83%@,.:)8A&(&A=%G8+,(B5C4D69'##!G2F.(F,")=-!/>1+#--<326:B22727+"=:4D>7A$&207A!*!"=(1=,6792HE4D?#8<4;4C8/;2,@3+#+&&.,7C"BB=:7;G>(;+5.C@3/C-A5>!'=1(8$3$&4,H&'//)+5A9@A9D.)166/,&7?>>3#84>C>E!.">=%B+4A)<0"1%'3:H)1&2A=//:682>1E9!+F&B-3<0F)/&A,BGGA./2D<C?*)17>=EG8E(A$"C9(>''GD=6/,%AAG1;??;1DH8%+A>.0.?"B5?9=A?@#DH3F7<5
@r3629
GGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTNCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGNACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCTGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGNCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGA
+
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
@r3630
CGCAGAATGGCAAGCAGCACTTTAAACTGTCGCNTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTNTGGCGTAACCATCATCGAGATCTGCCACATTACGCTNCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGAACCCCCATTCAAGAACAGCAAGCAGNATTGAGAACTTTGGAATCCAGTCCCTCTTCC
+
$1G/(:711H1%G:#7-+*HB5B95-)%G3D3-!;5,?!*1<7;6."#!:7A(+D@::-/:;>,22'7"13EF9"?"0((*<=G-"/1(466,;C?CE1F60E-(6#9)F:658=7->4A!9(!;!?#1<-"&5A6D%#C2D%GA7*.#8EGF'3G)@$+..!)A;02%H(5C1-.28/64+?DG'*&7*9@2:D>@%(&3:)-9>+:277&(($7@7=?D:,#2*=/F"G,:#56'56@'7=F*;F6"C%6",5<7C:"5%60")D'@%,>="5C-#@'#1=!?5/:',+#1:5=")@=%?1+-FG*EC?2(?.E7<,<=F40A755)1.'C;(%44'%!BH24,$F3;;0?#719!0;&&9;:90>2.*>
@r3631
ATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTGTTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTC
+
.E@G+F',;H36G$<0.(()#C0<3GC;)/#>#"79%83?94?1&B=GA)G(;;0#D%CFB$*:F6"E4,AC!..#<#80#5H2$)7&!,@0E3"2*E(!?B!G?A."#)E<$8D3*50?:E#D0<6>7+$!E21HF#$(DEDF@%)AC"%0(>-#!8:H$1<&,44G?@2'!+@1,'!+G;.$D<D.*5"-EE-7G
@r3632
CNGCNGCCGGACAGGNTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCAACAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGNCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGANGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACNGCAGCGGAACGGAACGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGG
+
)$!$!++'$&&%*$$''*%&'#!"$))"+%'&'%)"%*!*)*+#'!"%!+)&*&#!("**'%&(*$($(++'"(!$!*%(*#"*'+*%*$(#(%&&'(&#(+(#&*&*%)&$')'%(()+&!+&'*(()&'!$'%#$)#$!%*($&!*'%&*'(&$+$#+$)"*#%*")!#'#'"('(#!#$%$$*$$#+"'"#'%(%+%(%#)(&"+"&+'#&%+&#!#*#('!""*)**&!*'#!!"*)'!$#+)+&&(%"%*#')!*%#'#'$!&#$+&$(+*(!)!!#&$))'"+'%"#)*&%)+!+"&*!%&%&#*!"*%'$(!'$"%#$()!*#%+$!(!'$&(%'$()%)**++&%&*&$#"++"#+%%#%#!*#")+)$&'%)+!%&%!(%#%*&'#&%#"##&&!")%"+#$*&&)&(%&('!*%++*+!+($)((($%
@r3633
CGCCGGGTAGCTCACGGGGTATCCATGTCCATTTCTGCGGCATCCNGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACNCCGGCACGGCAGTTCCGACTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAAC
+
5D/#.>-1G971@>'.<0=4%$-8!:'+1?+1'F!'")+1@2*A,B>2+<!+0)*3E5987.($*:-*18(<:595#??+$)?7&1&DBH"=2'3,7<(3.(A<50+A<%06>C=E@D70C&(;'1%&;<'527/!.<E5*!GB&&,;9;1+01B)E3FD($E;%3!:=A;<>?AH'%B.9:D>@DD-''(.581-.#?*C#-378"
@r3634
GTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACNCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACT
+
&C!,?D#61;8+6B3%6<-(DB(BD:;)E6<@?7)21&-;4''::EC4);B!+*4')2*"&?12?@-+<>H)-9'7#$8D:FE?.:'761"9"=HB#$B.#'CA3.;$$$&@$C;$2%0<H2B*+'4=67>#BC)7;F9765:4CB32H>F;+34;>HH-B>H=G-@2A5B57DF<HE3+,B+;#,@5E809G79*5;++**#F63!1''7%/EH8(@.G2#B7'>1=4&8@1,1()$C77H.#*FC@#C"7CAD;!A;?)%#9GF
@r3635
CGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAAC
+
4G"9!,#A76A,51B:,%;D!4A5=$8,.!B4@3@H=$?;)1;-?HF""(9F?8,F*%.(1)1C!
@r3636
ACTCCAATAAACCAATATANAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCAT
+
94(<D:4DEH@-9(,7!6)(/0D-2B$%F+'B<A?"C:3C(#)=#A(2%'G%-+;'F:%;(#.E,+.8C91D,+0'82*F*;.'$5:=?E4
@r3637
CNGNTGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATCNGAAATATTTGGGGAGTTGGCGATCTGNACGGATGCTA
+
'$%%%(+&!(+*!#')$#!+)$$)!%")&"#%"*$)##*!"&%%#(!""'$%#+%#$&+%'%)'+")'*++*(*!''*$+!'()%(%*')
@r3638
TCGTTTCNGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTNTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCNTGAGTT
+
EH++$B*'C#);%394:(%"%,B2+6'@$/=."8$@?&'?,?39!!F(%-&#0)/A&E(:'.9F@C%#/%*E6903=)@)!>6&3DD3><4:=D!$-DB)!*A)C6DA2+1;8:%&(#6(B4A7&8D#09.,H/GD@-6-'1$5%(.C.88:*9,!?'!/+<'662++1>?$/'D2"B?<+
@r3639
CGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCC
+
G>')%!4%*(23(6C3A*AA30>C;H."(+*8G7#,2!"/:(/34$*H5.CF:?*!C17G*G7/69H>7?9;7!4%"',E#5>"""(G!<C*59>D3D?987$,0&8'
@r3640
CGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGNACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCNATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGANACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGACTTCNATACGCTAGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGC
+
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
@r3641
CCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGAT
+
HCH?.-8#C;>DF*H.<D?A7!51C(1F$:@>:)+B05<G0%2H9%6$0#7B;"<2E4%$'$H#/7,&;4+&G5E/7"53#/0,G7'=!(.6!*=24F.@+7/</B%<A.
@r3642
GTGAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAA
+
<H=9)0,@><';<6';-17?"<B+8A8$1$"B?".%$4,*=(@?E)=;8:A5&C@+.=A%A1;9:!5@#94=A$"%!
@r3643
ATCATGAAAATAATGGCTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGANGACATCCCGGCAAGCATGGCACGCCAGTCGGGTNGCCCCATCTCACGCGCCAGNTTCAGGGCAAAACTCNGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATNCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCNTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCTAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGANTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCNGCCCTTTCACCACNGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGNGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTGTCACCGTGCGGGNGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAC
+
:2,H9(2,C(3#0.F6:A4?8<9?@G)>!#:<!=0/726#/8></(=B2C.E3,=>"+'<2>9?(%G<C,33F.H:<&(<;(3",HF-66%,3%*4+E8G&+%65$B@<><0<(:;.0H8%"C5E,5&"!#//A3?(2156D01;',"C?D%F@";=3#/?8C'0@%E$//&!(("F5+3A>@(!HC&1->GG>4*,AA'E.G:B1!@.7>@!B7.#*4A!/>56;?H&<!A"+0.!"$D"9.);8+AH-1;00%44='C?@9F75H#='775<1-/?.'33<F%3;,)$&,=A0??5?GG5%6&>A3+%9C44B6G,)@4.-.&%!G43>#)9C)<&2-A&H$@,BH@$4@=2=:'62?H?>-0!)"8"7?@5&8'"?5B@&E'!!##FFD?-G2$H+8$??#=/=7F'2"@?-7.<;=>$=,>BG,#&EF"'<*=+59H9>B%C:(+B#8)*C@4@,FF-37C"3<9-4F*"H/!!:<"1<<4*$3?/?3(7(:@.D,88-.6/G?@$0".'$<#%AG(*0'25(G89/4"=D8H(G/B/F$H#&!*,E5#.:;D;/"/-0A!'>:?62'#-9?7@A>C/CH5'<3#"4FG$!;<,D))3DGA>.$-=43@,84</E1C@4.1"B/@*A">(';,7AC9G:0!.;$)@(0@1G-B$@.>7!9;>D*7B5&'@",-0*(B??"25<)?&9A:@3?G1<>F*B,=$51;G+?,F9H+/5015)73;@3#:)&E"CD#,F>#880)(5;<)##@H1%;&*459H'@2-*).!@/")03*=A(G%D;)?F&205:4+>/0"7/#+E*=0,4."<!!7?$@C/86DEF$4A9>"!'::&,EH9D4DA?&"+&97()C6GB4@47E6."268+5<&+H62<@-1'!<%C.9CFB+8AGE),H/,2(1/#-&::.'"GG<#4=:$3)'>1%<-?)39&':.H.4"F9
@r3644
TGCACCGGCACTCACGGCTGTACCGGACAATGNGTGACTGTGGCTGCCCTGACTGTCCGTATTCGATAAATAAGCAATACNCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCAATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTT
+
:6'(#>!>#<''"5:>B-D24?BH'7,>:271<@D("G3.62>-7B(##>EHC->=E-$!14F).H.E-F,4$%80+"H"6'?";%<5421?<>(0-:?G)DF,E&1H$1<F8*"ECB*0E1G;=C=9?%CH#$76029##:4D)?;=B>,"?&)7A99H$63:*H#H04!"2=(
@r3645
GATNGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATNAGGCCATCAATAAAANCNATACCCGCCGGAATGGTGC
+
'*'&(&&*'&+++"(*&'("*#"#*+$"("%'+$(!*#$)$#$*++"(")%"%+$#*#(%)''%#$'((##!&#&$%(&'+("'*#*%$$*&"#&%+)+
@r3646
TTTCATAAGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATNCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACAGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGC
+
7?6."D2B3HA+E+)$;C7C&$-824C3/#C1E5/E8D&1?EA572$C$:.<D$*$5@,%#);H&(0?H54D9>-8<)!&"/:D"1F-30&68A@?2@.7$%:?)=A?*B>=7HA77G5=0'1??/F,+$0.9-HH55?;+"H)$87F.",!$?731CA)6:E=!!)4):&#=9H.,=@*20.5-??+B->-:6(=$:$5$,!FA'0'=2E1?E,A;9$C>.8E+E=2G:A7"4&A601><7EE%EAB-A+/?C9'#HBD))-")6/&870H%4EB=@,-0F./5D41+!:G!1>.D>*'*<1G7
@r3647
AGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAANCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCNACAGGAGTCATT
+
<$C,.6@9BF10!,+41;"/,6:?(##5F;8CF=57B-?))C@0DH*#.51+F'?E%F)47*34#,B+EE4B;(>(9'*@*%%-)@A6"3-%11687'B-:+7>;#>;"#7".B+83.F6EA&:%/)0!.;@+5-(H/65H+"<98C8,)(;!D*;A3/B2;C&09,:D"(=&GG;H)5=-+20D0$9(CAF),5417"!()CH%)A/8<)
@r3648
TAATACGAAGGATTATTCCCTGGTGGTTGACTGNTCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATT
+
@(F%479-)B>!&70CE;+.F!@35'706C::<8E!A-9?6'2964>%04&41,>B@&/'.A'0"+F8)!*8-52(./6,"B7?+!./9(5(D,.6'!>*3)G%?1?E.5,6F/$GB"%9&F>>'AH(>,
@r3649
CGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGANCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTNGTAATGTTACGAAGATGGATGCCTTTGGC
+
*G6.6(;F4+H"2/?7"A1(%@(G>>847%.&EE#C+2?E4.5:0):"+&BC,)*9395CG.-F#0E"6H3$H/#*:&.699"-+;,:'1#76,);B$)41A3B'7B990HD->!.4E%-.?.&2%A*&;361B;"/%0!F1?#5>"+?68H!%=B;6<+*:=/*/@#FC%B+&-*'1/7A/;!BH2/%BG.7DFE+DG&87"#5":BF.$:D16"9H0$BB+5-+5!3A;3,-G!/!/+9!<B#H;E$-E-G!6=.=#D#>A""?A9<H-3<%D'64!?1+?!C51/C8+E=*.+&;2*8,8*)BG;5,H@=)G4&*)@1,!!(3;D)>:E
@r3650
NCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAG
+
1#9975+:EG</3#CD.>%3.?6&G0,4,.B+8*A@A5F9/-<'#1,0*>5
@r3651
GCAGTTTCCCTACTGTTAGCGCAANATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCNGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAANGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTGCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCNTGCTGGCAACTTGCACAAGTCCGACNACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTNACAACAATGAGTGGCAGANATAGCCTGGTGGTNCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCNCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCNCTTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCNCTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTATAGAAAGAC
+
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
@r3652
AGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGNAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCACTGGCGTGGAGTGCAGGTATACAGATTAATCCGGNAGCGTCCGTCGTTGNTGATATTGCTTATGAAGGCTCCGGCAGTGGCGNCTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTNCAGGTTGACGGTTTTCCACCNTCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGANGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGACGCGTAACGCGTCCGTGGTGGCACATAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACAGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCA
+
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
@r3653
GANAAGNNGNTTTATCAGGGCGAGATGCTCAATGCGCNGCAGGGCNGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTANCGTATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTNATACCAATGACCGACACGGTGGCTTTTGTTTTANCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCNGCGTGGTGCTNTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTNCCATCGACGGACGTCCCACATTGGTGACTTTCACCGCGCGNGTGATCACTTCATTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTNCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCNGNCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTCCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAG
+
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
@r3654
TTTTTTAGCAGCGAAGCNTTTGATAAGCGAACCNATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGATATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATNATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATNATATCTGCCGCGAAGGTACACCATTGCAAACGCAAGGATTGCCNCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTNATGTTTTTCTGGCANCNTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACGGATAGAACAAATCCAGGCTACTGTGTTTAGTTATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGGTGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAANGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTNATCCGNTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCNGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCANTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGNTTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAATGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGGGGCACTACGGCAATANTCCGCATAAGCGCATGTTGCGAGNACTTGCAGTAACTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACNTTGNGTGCAAATTGCATCAGATAGTNNATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCNGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTNAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCA
+
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
@r3655
CCACCNTCATTTCCAGCTTTTGTGAAAGGGATGNGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCC
+
C7:+*)9(7$++2,G+)6&?7/(EC60A)E#EB.<.)':F?$FF>)D*G(9$:/D?*ED<1>96+/C'D7$3..42'H,A0BG?A:>@)5,D2C;74-($0A%%/=@89,#0'5F#-D#0F7"E22$*7#+201(324HC=D5G30,#-E.6)*E!26$..2@:D
@r3656
TGCGAATGCCAGCGTCAGACATCATATGCAGATACTCANCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAANGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCC
+
($'E3)GB'#283D)5$B%4G@2$$4<8$9+C"491=8#7*?$=9H::F7<4B6'-=F(,ADH:1&57'"'*4?%35-;!1(*/13<3#-*+H>77G#AF)8")H/(69-=<-E/D1C-#7&/6=1450E!D@516:->3),#
@r3657
GGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGG
+
/.H;7!>'9"D-*3F58,%/B!6"@8+1!134GFAH)&&)CE<=
@r3658
NCTCTNCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATG
+
-$/%B:5&4%B"/;E%:0ABD+5@&9$9"3H<<-*,6*1@3+=$A@/FBB5.2':');44!C@@3"1396>66#:3G%@C=2;-%C7G>,$1>EH56<58)F20$.D%!(!6<>HEF0!7E>:0-!-'>HGH)C?;&5,5&81;-F->;E6/1AGD1GA8&<*7CE/492H=GED?1>A8>5,98,-AA2!5!,*D#
@r3659
NGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGGCTCTTTGCCCGTCATTCACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACTATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTNCGCGTTTGATTTCCACGGATAAGACTCCGCATC
+
#,/9A7<1<;"&A"5A++64&,$G@*3>6,#66+2;<"5G;CDB&C")/F,C,G*(AF-D0@999#6G9"7758.9.A7)/'@81.=>1':;6AF"A!%F=/.7+9/.33+!(%1="3/7'<3'2109(#($H"E86))40=&6!C@<G-H3>)5($&B=)A+4/&=>>.;2*B@A!)0ED"@5/#C!@-:$4;&,>C>:26.1B:15*>FC>=*5)G&%$6F$E47??8(D+#D4&??A*<-?#'@FAHD+F=*,F-D5**32D556-*1-H$$?<2++E9%<E10F(6/H9.@'<=!H",:03;>?$(D:E!'.=H?/&%80H8'31'*94&B=0E19"!!CH0G59>E3(
@r3660
CCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGANACAATACA
+
/FA;BD:.4%5A%G(C31$,'&AB(6&=6.!$1H!21'A):%5<:.A9&0$4&5A("2;G
@r3661
AGAAATAGAAGAATTACAGCGCAAGACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATNTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTACCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCNGGNTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGNTGGCAAGGGTAAT
+
*++"'$!&&((*$$%'("##))$+'#($$'*#!&"$&+$('*'")&(!((&+&%%")""$+!&+$#++(!"$+#*%'(#!%'+%!!'+(%"(+!%&$($'$(!))!&!)"'%*"'"+!++#*&+)"%)("#(**&")+)!++(%*#'%)%!&&(*'%$(#'%)()'+#)"$'$!)&$!*%$*(&)")*%+'")*(!+*&+%+$'#")$*(&*#!+)#'(+$"(&)'+&()%"$$'($!'!$)+$()%!!#+)$&%))&!!'##&%&'!&+*!%$"#()!')*&($))"$%+%""%$#!''#*&$(&*(("')*''&$*##$*&'+(#%)!'+(%)&+
@r3662
TGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGC
+
=B.C/BFGE1'@G+55E+)!!ABF<2HH)>&7<%.3/=,>B<&<>*$.A+!3#/.<2A17.E>&,G'-413..2>?2FD?$*<".=)4?E:.'#'*G!99$56(0-8%)2A<!<(!#=:*G!)'5.3#0"HG/5H2"5"@<%9'5A@!;:<)C2=E/B+1;42->;4&$6!-D@!0C:B#%/H-=44D<;:D++7F3D$C$1(%/:5+=('37'(H+A8-4.>GB<381*/'B'9.@'GG'9%4:D+6%/%A2EC&G3"<D)!8-9EF:C&HE$&!?;H@!B:C&=%#7$@<9C*3$3"@'E@.2CHD
@r3663
GTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTGATCGCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGNGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTG
+
C%6"GE->CB!A"+9@#8F3)?.F<=2'/%+6-$.5F'$42@&6G/4<-*9D"3G<A6-97"1F<1093(A9+G=:%G(H2(7@,72E/8D5H<!D7?1?$-A;&;BB+2=>>)GEH5D,8"'#+7-+)-,@=>0%='63</E%6<&;0$=;1$4H8?9+2E969#D&'>+CA?>AH$)=3>>,6,&*!:(A*)1-4.?D;E/B3:H)6"$E(>!50'E&=4'G24093?1&E.+3+@4@C=!78)G%9"$H#,F"H*+:GBB&?>C@/<?*A%9?2G415D.*6/145=0*6.(*>@5.AF##1;;9:0.A'8BG0"F3-&A<;B#49F*!02(<)2&%*C.).'>
@r3664
GCGGTGTCCTATAAGGGGATGTATNGCGATGTGGCCATCGTCGTCTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCAGACGCACAGCGCGAAGGCATTAACTCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGAGATCCGGCGCGTGANTTCACCATGATTCAGTCAGCNCCGCTGATGCTGCTGGCTGNCCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTG
+
09'>8?C;)F,$#3:E+8&="FAG(((#4F3G:,>#,A$6%77<1EB:-BB(8+B1:'&F%B,0H)7$??)0<$*/$=:@%F%<!#AB!8>$.#@94<>+G*<4!F8!!/?,)0%'D162:3-3G%3G!!!A-;>3?:<9G2&H4*2=#36#+"1F!2;;E*!:#,/8G>.E('/GH9;7"B/$<+D>4=43/3">$B*%;,3+EC'"90816G,55BH*C-"";0F3!D)>@(FE*,@8,0;2'7A9$1:;#"@4":08?*F#5<7;6F(5;0+C$".<;(<%?@%9@-H&4DD'#F6"*.'15BFB&$@.@G/6?=G08+#GCG3+GE,<1"9!5
@r3665
TTTNAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCNTCGTTTTCTCTANCTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCC
+
&*)!+"##*+"%*!$*!&"!&+))'#&)!!&&'"+*#+%)*&!#&*"*+'&)%$%+"&&$!+)'$"$%(!+#)+!))%)""#!)#++"#))(#%*)(*(#$)%'&"%+(!%(+)(#"+$#+&'"#**&*"))+&*('$"'(*$&)'")$%*)(!#+&!#++!'%#$$!()&&#!''
@r3666
TGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTNAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTG
+
/$A)9<-)$C#F>&"7#*A,)B%D!7.-('G+'@<F;3?-F1C?<%+0H":#?(747"6%9!H"%/?2F09;<)%2"%;AD,/;0?@C<8FG3.?"@7H+7#C!DF@%G57G,F"?"(,@=!F/$@,84=%8389:@A%C+'=2%+GD$6GE!$;5<$>50/*'1=&"H;BF/+00AB5!1#((%+4H809@,F7%?$);=3).1+/;5+.;&D&!7E$!"A)+H2:G#:
@r3667
NGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGAAGTTATGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCAC
+
#+")!*!%$+(#(#$%!#"'+))#')!&$%&%##$%$'*#(#)"%'*+%'#$(#")*#'%$'$!"'+!$!"'+!%*#")++)!))%(#)%##+#&)(+*')'$)$)!"%'%$#%##()%!"&(&*(($+%"$%"*$&
@r3668
CGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGCTGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGG
+
3%FHE8+7"9E:.8!A?:G0+'&-5F">+816'>'7H(AF3E22<@70F87A&HE!.!?-H196,*,4)-?BD2?+2;1%C8*$->.:'$:2)ADD!/=H<),,!"B%)(56D(")7('$:H6>;-F@.@D>&(?<H;%,G0F%4:"+G6)G)<8C%=9:H"CC=5+D+'-7-EC6>8>.C.!=1?:0C=H"0?#:,A<23+;H<",GB3:73&7E5!?!/:!(C;60=<!"F537*%$/(:G7E
@r3669
GGCTGCACTNGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGNCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGT
+
73.H/3"3$-)AE*92;7H+>!@*5'=!$'%08",<=0(/D05%B33#C)H""=6)"90'*G$1?-,3.#;&$>1:8&.$9A:A;):$0%947G>"*)5F8$"/357;GGD"1<A+<$88?;DG==58)%=G*0A-3A5D2$?$..%+9:1.2=5589$-'!>!@"D@(@DB*'$A:C+59F*:)2$/&%1,?=&G!4.&1=@1+H,
@r3670
GCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTTAGCGTATTGCTNACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGNTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGT
+
%0?$&D"7/&F'*CEG8G;8E=D)E3.C#EFG*5'@FG4&-*=#E,B?3+):+E)H8)'&,"!1:),#8:!@"GFE,D%BF)6*H(.80$'@=-G647#F.%8708H+038-)G/G4/8/4$
@r3671
TCNTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTNGAAGTGACAAATTATTGNTGCCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATANGATTAGAAGGTCGAACCGTTNTAAAAGCGATGATAATGAACAGAGATGAAGGAAAAGTNCAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGANATGCTTAAGAAATGCTCGGAAGGTATGATGCAGATAAA
+
:)*'!*=.3'G*HD@8-?D*%"D%4C(*/(D?@"(;E=E5>2@":>G4"<;&18-F;@"@>-;;5:?=A7)&8@A!8/F*-!/3G12049D2HFG"$>98;392+G1AF=%E;=(#4!;D4A=$>.:$!.<?!&>'B$358#)A6=,4</<H3(@(%-907C/@6.6C/+!"''!16<608$:*4G+E><C<57**;36*>5?..#,)/G?CFB-"2=4<-F)$:+BA687;!0,"7:F,.9147!B&9F=(<-#C)<=/'$(A-$2*#:,:8?H4>53*<439@'#;.%:%C8,5+%G.+*,'%E1*1@?0#E9?FB;.0+!BA585#.=.91-:*:,"='F-2-
@r3672
CTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACNTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCNCCCGACTGGCAGACACCGCTGAACCGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGANTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTA
+
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
@r3673
TATGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTAACAGTCATTTCTCGCACATTGCAGAATGGGGAT
+
*!?*)3"14"<5H1&4>-<@E/9@.1!B+/+@"A+9"="'7!A19B0C+37//G,;$7HAGGB&@=GB31:&>GE!::+H=B;,GH"H?:-!:
@r3674
ACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAANTGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAGGCAGGAGTTTTCCGATGGGTTACAAATATCC
+
=7&<<0"3;!/H#1=8,A%)ED'$C&#=0>";9D/E8(,;%+C&2A.FB9<6>#&A7+4?&%/F4,@==H3)HD(.7(*31<?40>=>D5>,#1%$#A#2-+9@4&!"*?&B95>8EB7E0CG5.'AC02=,&C/)E'3&>3#(=AC>317!>/%E&@B6,5/=%>2>2'/GEE$'.2-(A-))601F7$$?;3%(1?.72A'A//@/#D034/C5H,279'952H-%,/HD$)&=HC8((080H8<8D!F*H7-)056+'+8!30&<3/4*7;HD6:D+;/*CE>3/:%!(A!=&H/91/DF)#04,G/-@6%1#FG5E"<).57&%)7.1DH'&<$&((>,.D>'2;141*@>C1;
@r3675
NGAGATCTTTAGCTGTNTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCNGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTNAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGTAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCANTGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAATGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGNTCAGGCAGGGATGTTCTNACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACANGCTCCAACTTTCCTGACGGAATGTTAATTCTNGTTGACCCTGNGCAGGCTGTTGAGCC
+
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
@r3676
GGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTG
+
F?3E#+)2.:C"A$(!(3>!#)3+9!56:,/D%@,6,;B-@G9F96$>E1!(?1G"D6,A9"@!=452<&921;?"B2@;=C.%DB'EA@;1;1HE@EB%;6"E'/-<546)(343<4%A"$H/C?@"+B(F7$/>;<6G!*.H
@r3677
CTNAANCTNNACACCNCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACNGACCGCATTTGCCGGNACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAATCGCCCAACTG
+
(*%#)!(('#*)*(*'$++%#)$(#&$(*'(%+!*$%(#&*$+&)%%+(!#*%!#&$"%%"(*!+($""!%$&('#!**#')%+"%#'+$+$"%'(&$**"%#'*'!%)*'+#*%)%#!*"$('!)+&+$)&$+(%"'$''$"*$+)#"!')'!*!#'#+(!"($*)"*"#*%"*'##"$!()#*)**$+$!")")#(&+**+)#*%%+)#*("+')++&)+$('!&$$)$+(++!'(*&'&#(((*&#)&"'##+%+((%)++#)'(!&((%)$$*!&#$"*'*+$&#!"**$)*(##&))%'
@r3678
TGTTTTGGCAATATCAACCGCACGGCCTGTACCATNGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGC
+
ADAGD!*,?/7;(?'#?#A>4!C0F$,,.&8)5)'@940./</>'$(0,B,5!/&/G"B<:71B=:>&<')-)C#,?:#0/<#,<$()-3%2%*4+C'/E2D*8")A7803'
@r3679
TTTTAGTCCTTTTATTAACGCGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCTGAATAAAACAATTCACAGTCTAAATCTTTTCNCACTTGATCGAATATTTCTTT
+
5=$.1+9&4!C=A,2"*54*<9GC:?#:@1!"@HC#+C.:5$A?=0,(;!E3#C%5%#%,".09#40B$<1/!&,(F;G?1#(H1BA7"688;6%%"31-H:<B%GAF3:+)DCB(6#5@BG7491<3?!*C&;!>>!20&=?%>//F!2/4=37ECC#
@r3680
CCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGCCATGTAATAATTCGTAATCTTTTAGCGTTTTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTNTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGNAAGATGAAATAAGAGTAGCCTNTGCNTCGCTATACNTTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTACAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGNATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTGGTCATAAAACTCTCCATTNTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTCATAAAATTAACTGCTTAACTGNCAANGTAATACAANTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATAAGTTACACAGGAANTTTTTAATATTANTATTATCATTCATTATGTATTAAAANTAGAGT
+
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
@r3681
TGCACTGCAGTTCATGTCNTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACAC
+
&C810;B.!@$.B)5=#(46)#5B1DE&2#'>??!16%/B30!3?7&FE1'!6'G2
@r3682
ATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCCACCCACCTNGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGA
+
B>8FBE0<50&$EC?"%+9!9"'/'A1(G,.AB@761/%-:D.:0"H-$/0;A(4AG)28A&:<;B9$&4!!$94%894>H/-A-C3'*35A8$1$G.@/>'++&C2;(3!F)8+>,67,%$-#$.=-9>-=1/'8,E"6)61):/+E6F.&?=*)F#A"3
@r3683
CATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTG
+
6">'$E8+/113+:#6)D8D&0C)B@5'D9'G<.:6)<)F3,!?-)%:7'>@%41'6>
@r3684
CATTCTTTGGGACTCCTGGCTGANTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCANATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTCCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTT
+
HE7HH@5:1!F#*:HF5;GE6*2<3!*+*-=,8F6&%-EC8#>C4-+@@0!.F,,5:@9%5138$!3:)H1&38:A10B02&0D0@1=26#(E.-("@-%E>,G:"/C1'E-C"A9!H$6:753"AB,+;,F8(?G2!-%>>B*%"$65A>"B#8FFH/?3'-,B6(9,#<5$>&'2:E7:!-$)8B;<,'E5-;$95*,)A10">,:!.H68>*,=GE(>A@8HG&131+59H/?581F$CC$925E:9.7E,0$?-3>*$A3#H$52);E.&.99#6F?,H$*,H57."D$3*@1#B0"+*F6&4!%;!B<%+/3'D$6-H7"897$*1;081:62%4H13@?,"%.)H
@r3685
TATGTAAACACCAGGCATGATTCGGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCNTTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGA
+
-(3"=1/08??#,.7EH:=;+3<>,91H&:>;%%8!>D@=B;;(AA6@4F)F+@0.2$04?%9'E3+*8?D::!36.0,-"&#$,:&B'G<$3#!&:2.'+0F&A,?"?@%+.BA=&H/!!F6G6<$-1;C+30"4<2D/A$=<7*D"CH!67908.D-%99*)5%&A=8FC;1'F/%:,41@.%&2?&6?<2%?:;,0996)*C>>84!!<E6123#0D=E*,.,!6"&0;7(G*#0(+<#,>!;$(5
@r3686
NCAGANNNAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGG
+
&!$"*'$%$!++)'#%()*%&(#)))*'#*++"$"$#%&%"+&!%&$*
@r3687
AAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGAGGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTNCGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTAACAAAGGTTAAATTAGA
+
?G%6ED(,1"'+7"-$:8E(%@$'%HC4;(".30-'=;2#E.$H9#G'&38+*7%,5*30!$(@>0+C:G88,,>,9>8DC)=7>;%"&8)"E)&3791'C.?(41/F/>H?'C3EH"E0*44)(;.70*%G(0@;6"2,5?2$-E=8!:>$712972H@A-D;+2"D$!F%6:1+E>2(+78?F25@36"E$/?$41;@C4:"B49@-+@7+"!'?(G%+D;.-$13"?E
@r3688
ACCGGGNCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTCCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGATGTGTTCCTNAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAGTGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGA
+
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
@r3689
TAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGNAACGTCAGCGGAANCACCACTATCTGGCGATCAAAAGGATGGTCATCG
+
)9+7DH8.<--<?D;@E)/-8G)=!,'HF:$>">9:@<>"%@0$%#BHF,-<6F>;#"C.7'--/5"+#'>!-G.DF<2<@96*!G;F+530>';"6@8
@r3690
GNATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGNTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCAGGCCGTTAATATGTTGCCATCCGTNGCNATCATGCTGCCAACGTGTGACCGCATTCAANATGTTGTCTGCGATTGACTCTTCNTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGANCAGGTGGGTTGGGTAAGGTTTGNGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGT
+
*)$'(+"(*$(()'&$&&)#$%)"*'$"&*%(#)'#(%%)*')!#")%!()+&$$("#"#%$#$')$$"))*$"%*)()'&&")%!"!!('"&%%)%$"+%)%$!($)!!*$)#"%*$('!)#+&'+)!+(%**((%)*'"(*()*"&)*()"'+&#"%(!'%"(+!))*"*)(+***##&'&'+#"$*$%#**(*$&+'(*%)+&'(%&+#!(&$$#%)%%++")+)'#(!%*#")($)!+$!%&$!+&$*'"&())'!&#$%!&(*%'*%!*+*""&$$"#"*"*(!#'!$((!)+"("($%+&"(%$(*""!"(+&)&((%%+''(#'*#)#$!(+*(#+#&)!+%!(+&#*+*#(%%))'+&')$#!"+*&*&%$&$%%%%!""%!'!'!&&#"'"+)%!"#'$&%'(%!")%&!&+%!'%%)!'#)))+(&%(%+*)+%'*'(*)$+*(*'$+$!*%())"*"&&&!&#%$!($*")"#)(+*%*+$"*)%*'%(&#'"%"$!(&+$"(("(&#*"$+)*""#&"++('"*(*!)%)%)*(%('%!+'"'!($"&++!%$''#!%(*#*(*#%#'"#)$"'#&##"&&%"%*#&#*!##%*!#&%(#
@r3691
CCANCACTTCCTGCTCAATCTGTTTAACGGCTTCANTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCTGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCNCTTGTCGGTTACGCCCTCCGGCTGGGAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCC
+
(#$&+)'"#%'"%!)'&'*)#*$!)&#*"%%%*)*#)#!%)##%#'!$&(+"$$+*+&("$"+$+!#&#&%!&"(##(*$**"#'(%(+%&$(&*%(!'+"+%$#'&"$)*&)+(%&'*%&"&"!)"&'!!*'!++'*&(%)$*$)&")%+)&&%(%*!"+%$'&*+$%%+))"#$""$&(%("&'&*('&*'$&''*)"()#)!+'"#($!%)$)&'%!%%#%)!'&$")')$'*)$)#("")&$$%%'%!"+)&*"!+)"'(!*&*(%()("%'"%)+!)%)!$)'%*+'%+%!%#'')!(!"'!)*("%!"*#+("$*$)$$+!#%(!')$*!()('#&)!')%)!+$")$!$!)"!()%*&*#+&$&$($!)'')("#+!*#%'&*$&(+$+&+&*%'"&"!#!"!*'("#&&"%#!"!"%#%''((("$##'#"))+%++(%+&!$(('$+&(+#"')$'#'*&"%#!%")+(+*#!)'%))(%(&)+($%'&$)$'%&'+$*#+*!+&#)&$()%!$$$$$
@r3692
AACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATA
+
<@3AA3"17,60!C$??A">@F95.BB/<?21##+'F<D&:;=)F+4G1"B1D!3;(14:4:;3AA'"1+'F<)%2)G:?;2?+45+,>,1,@;3$1!F4@+:#:-8,#/H?-/:<&A9*$-,*$4<>9E:3.$!EE+?>"A)%?5A;2H1"';68#F+8>0).G<A3#E2-05,BE#%4H+&$@/@0F1?;-0>-FA,F$G0;F*1&DE00=;6-+&)*"'H=@E2'-
@r3693
CNNCTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTNGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGA
+
!(**+#"&'!!'"+*$&+'!"!*%&(('"$*'$(&**'("('*%!(&#*"%!$'!&'%!%$&)!$"!&)*%$)$*&#++'%$!+(#"+*&%!'%(+%+)#&$'$"(((*)$"$*(&($#%+#!!)*)+$"%)('"'$'"!#)""(+&'(!'+$!*))"$&'$!&#"($'$*!!#("'(!!**&"("()'&(*"+!(#$!*!(+'!&+$$%''(+(!('$!*$
@r3694
CTGTAATGGTTGCTGTTCCNTACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGNTTTTCGTCCCCAAATCCGTACCTGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGNCCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAA
+
(E%:AG$-H#"1<;G?*G(H((0;/.A2<G&&9,.G%C8,%*30!+/6><7)65?-083&<)!990/!2G130%0'!-=<E,#?=D7!/"@"=F#;1+(6-.0+A.E1*4E+#?$C0%"E?9#60A46)C#7+D8/A'&,&DA,"6)!>E"&@D&.!C0@F:299.GAAC+,6(08&HCHC3%C,G"/;"??638+8@#9C?:%)#5DF(!5;0B2C12?7"="&H3,H#E,,;%0.'<#(<0:1+/61?$4;H',&,*#"=:B"#-9+&'*F997#52)0F&F<3"H*'/2G=<C06-(H(F::9G4&C;HH-&%)+C.!4"#
@r3695
NAGGGCTNNCNGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGNGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCNAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGNCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATNC
+
#''#')$)"%!%+%$!*"$&')")))()('(!+)%!$'*")(!!&#*!(+'&*$(*""%#))##'#&+"+&#%+!("%#(&+'"%%(*!"+"%+&$%)#""&&*%")+#'")(#((%%((&*$&!"(!##'*"#)&('%+#*&)((')(%+**!+****#")%"*&!!")&(&%(#%+""!#'+''("+#$#"'))!*'((#*(&)&!##&*&((*)*%'&)!")#)%*'*+%$***#&%'+%)+&!&%*)*'$()!"("(#+()*&%$")$#$$$+!%$%$"*&*+)$"'"!)##$"*%*"&&(%+***$)*#$)))))"#'"#+%!&#%'+%((")$%"%++$(!"&
@r3696
GCNCTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCA
+
&(!-$)6F<9!2F1%3G$!6H-#9.'6!=3F!&7989>H@<EF&#E%,D+*;:B5*5B)2D&#6'</=D>C!A#(,5@@$<@7A7)192B&,<A">&,C
@r3697
CCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGACAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTNTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCNTCGTAAACACCNCGCNCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCNGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCNGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTNGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGN
+
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
@r3698
TCGATAAAGTGCGAAAAGATTTATACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCCCATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGANACGTCCTATGATAGGTTGAAATCTAGATAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCANGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCA
+
?">9"6<=4@'!*?$:.2>?"9@+$E2HH7G#'6+#+#6;2&*5):;7,8#4*7+*-1G3$E:1;<GC3@D1@3<9!60<1A*.5+6*315@4(?H,>D87?$C"G=4C!(AB)42BA3=B=&6!+FD31%8;1;'/-(<D<?2$)E1?2/<#0(20=.@/>@%*B!%!&$E"C"*95%=3E&;'//+61;:?(/48%$&.913H%46.4-),%6$GA:7/G'897@B34/#8(*G?C%2'<8B@:G%*@+E'F7@'-?%;,</79>>(E,B&"2.&41F#..#33F2@0F,(E.(DG60&D#!;@=GH#"*$H@87#83/B3$+3&D)!-&>G1(7.;/A#:+@=<4:CG8-;HHA2?0C;&.')(>H?3:87$(?/"+/>/*
@r3699
TGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCANGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCAGCGCTTCCTGNACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCNCGCTTTTGAAGGTAACGTCACCACGCGGCGANCGATGGCCTCTTCCAGCCAGCACNGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTNCCGTGGAGTNGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCNGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTC
+
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
@r3700
GGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGA
+
B)$9.<2B*$&?%$D;=8+EF*&,6;>@("<F:&"G1E4!*9<:&AFG,9F@<D.%&+-0#+7,*>...4=H(''&(H'$=**A'$/;H"<6*B()0)(+1&*@3EH,3!0'&963FH'3$H$!-@:D%=(4@HHH?:??5,?;CE$*..=+
@r3701
GTGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTACGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAG
+
$9'A42%;5<D6<2G?11-4//F6CE1&G0=C3@$2+@EC(3FA305&!(@$)99:?+1;A.9*BC!#<<#:'5),114"&;0A31>9G$0;*;,5!7'+=4(.)?)7,54H<1C8C05B6:BDE*D4>.5!!86<*<$#/'@;>@*+?7#'2$B/$%.4@D/0:DH(C2E37F&""D&;7"AE*BC5="GC"EA9%H!!9>.00.;1;H716-))&"#>'4E&C%>H49*6B335<57?/
@r3702
NGCGATCGAAAATATCCATTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAANCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTNTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTGTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTTATCAAAGACAATAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCNGGAATACCCGCCTCTTTCAATAACACTAAACTCCANCATATAGTAACCCTCAATTTTATT
+
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
@r3703
AATGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGC
+
)"5((0+2@E/?*#?%#=@*.D9%F:D;@BF$@&'E1F*<0/'@E")7)-&,B/>D
@r3704
GAGTGTTAATNTCCTGCATGGTTTCATCGTTAACCGGAGTNATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTNTTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTCCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATNCCATTNTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGACTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTNGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTA
+
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
@r3705
NGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGTGCAATATNCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTNTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTNACTNATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACANCCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACANTCACAACAATGAGTGGCAGATATAGCCTGGTGGTNCAGGCGGCGCATTCGCTTCGTTTATGCGCTGGCGGCGCTGCNCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCNAGCCTACNGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGNCAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGT
+
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
@r3706
TCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGT
+
-31B%B?6'#0B5CFB=</58;6>&A">#FE$C;78CE"<,4G.!GG7'=?9*;@'1$?0+D,C!1'99+67<?FG';"<=;#8H"FE4)40CB/-<73E%7:G")<C<3C89H&
@r3707
CTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCNCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAANTACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTNAACGCCAGCGGTGTGGTGAATATNATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATNGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTANAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATNCCCCTTTTGGGGATTACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCTTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAANCAGNCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGNGCTGAATAATGCTCTNTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTNCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATNCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGG
+
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
@r3708
GGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGAATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCNTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCNTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGA
+
"'4F4F3BE:G;2.9%F??-)+&95;2%;AG@>C$.)#$5=90"<29#2&+8<:0H+8?D$=1(%:"0&=*">F7E@8#.4,/B2:22#?7D%%0D.D4/@+66?,,6#7/0"%"<H?,4+0<;EG3-F,;2B;EB(?<#=?209.9+*;'C(:G<A+)-0C3-H:B0)4)6E%82A->;0&+4F@F.57!,"D):D>87C,7C>":)6'.3$(@G05.@G3,1#*;8":56=:2G;B$2'.45"D2)-<H>-G$7E1''8/08=>'F5$=@A+3E7%G82<5#4&--<E,C3HB)4C(359H?4:3,@'-C=&6#(3&>C6/B'%=0D?2$4/"E&?;(?,>&8E4F"1G*'A61E;=>C54FHE6FB-GB("6+0!%@/DA&>.F02A?E?)<!!?C/;-!E#8B/D*67.?$-17&1'FBAC'$+03/CC=EAE@EE;HE!,.@;+&<((A1%-"*":/F+5E'CH-39EF
@r3709
TACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGTAAACCNGTAATACNCCGTTCGCCAGACCTTACCTTNGATAACCAGAANACCTGCCCGTGCCNTTTTAGCCGCGGCCTGANTTATGCTGGTTACTGTTGCGCCTGTTAGCGC
+
D+D;/F-<B,8$)8=#9,0G"4./8,'=+D:,H$-D%?=.D:%>B6E9.6F5-(6@B632@??$2$)=0FA;$:2F634A(*:=..#'>*><6)#';E!;&5#;0%=.:A-$G45@6'B@#,5!"*@(C23*6<)8'+*C!;H!0FE?$<;3%,?>+(27F8C2>!);A349$,#%B*:7F+?=C#A=D%;=2=<,#-F:&+7)
@r3710
GGATAACCCACTGTTATTCATGTTGCATGGTGNACTGTTTATACCAACGATATAGTATATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAANCCGATAGATAGCCACGGACTTCGTNGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCA
+
=#B99F7A)1%B#*4@7>=",*#%,&+8#:G1<6.0%=3-<4/CD",!!-.-+1A:$1<"66#>#:'F/4H=?<::$!$D95:*%<=$:A.G2H8(76.48)93C:A=$H;C$%03A-$<E&"!:;/#<H3%5E,>7D(H(&7?C=/,93:(85G$B>$F$G(*8!G;'#!@6;305/@,B<847H/1#+HHC.4D7++>)1=G712FFB$;$B,>8?$/C;1,HG1=21%/*;A;#'!!H$"<4D!5(%*B<#7"+@,=&#F0*)2+C/95$;%%252<G>:'@6!?6*>;3)1<88=<$9-D'B(7*8##"?+C%)6):BH/3/D=538*GFD15&<E+H3BC16<"+7:-%G:8%3,&9<80/C?$+=@#D9F3GC7GB"1D.ACG$8,!94*C4':?5">"H?F7?;H<FF'*#$8,>50&851*3;A@>?=B05)5->%<G$.&.15,.$H>3F#FA1E69C1;06+H-.0*2:HG0A75=1#
@r3711
CCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAACAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCAC
+
8@.E6#>576@*(F#/FF%&6-G;5*?+076#*@78?22!$&A<F.#"-6CG*6/1:?*3#A<5@.G:&"D.>)0G&#@HD1#.='7*/F(A4F.8F!=!B8"=>$20&15G.F#GF,+6=BB0E<
@r3712
GATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGNGTTTGGCCGGG
+
*3@C3/;9%G,8D#("F'E8%7!B=(3'=F?,FD7'8+G%(%.EF:4C>6;E9/3'?2GG,H:?:=))F!-?1$41B$G;463?/91F!;@%C,B.9,%>9F+!:.(1F6<D;.1#))5'FD7.24(H)=;49-66<0H6'5;=!%69%$5(:*7!H0B=-1@&/#4ED*?';>,F!/A)2D.
@r3713
CGTGATNNGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCCTCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCANCGGCTGATCANCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAANGGGCGTAAACCTTACGCCGGACCACCGTTCCGCNGACCAGACTCTGCATATCTTTCGCCATCCCGGTGACCATACCGTATAGGTTAGAAACCGTCAGCGTGGGGCGCGTNCTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATAGGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAA
+
(#&(')&!+#*%%"%"&#&+#'$(+"++'($))""%!*"%"$$&$%(**("''()%%$(#))&*$+%+"%)+&*%#(#!*&""!"!#'+&###+%*!"*)+$##)&%""**()(+%*$%&!*!*)+*&'&(#%'&)#+*'%%+($!"'+()+"##+"(+%))#(+)$*)#)$#&""!$!")$*&+$(!)+*'&$#+&"'#$!()+'*%(("&)%(%!+%"*&&*$&%(#+$+++##!!!!*)$*)#!*!'*!'$""+*+($()&!$(*$(%')'!$**++%#"'$*+"*)#!&"+$)&++*&$'+%+%('"&$)"%"'!"'((%$'+(*#'+"*))#"#$!('*&$'&#()##%#!%+#%#+)'%%"#)''"#)&)!)*$($+*#%*$#&!+"!(+*"&(($$+)&%$"&*%*+"+#'))&#'*
@r3714
CGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCTGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGAGGCGGGGGCATTTGACTGCGCTGAATCG
+
H0=@4./&7,5+5F#(84$77(*")G4".3G*?4<?8D&?EF2:%7G3@9"C"/:.D!4?/?17:,?8=3FCC$<:9$(2D/,/#9"D$:7G*-?,$+HE#%/:D3HC,;F".=G-67<2:D1*'&%-HD5*8"D#-3=>,:CA('C"(H8E(73-.**-H5A+BC"+D'$(=C92E7"D7#9=62+@/A-=B:;B&5:!&1C5AA6E42HC%'BB6<;D0B>8-&>*H/,8A4*)DD"F&A!G11:(A-0E!#"%#GC#A$&@%7$"4H#E5-.1/!CH@;&8;.HA&>"-&E@/;%.H#"GF3@&+2.FA>G0-F-9"';@)D,458#C7&:>>&37!+<H(%D6F337<17;1(&6
@r3715
TCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACNTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAANAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTNAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTCGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTACTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAA
+
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
@r3716
CAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGACACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACNGAAAGNCCNGGAAATACCCNGCCTCGCTTTGTAACGGAGTAGNCGAAAGTGNTTGCGCCTACCCGGATATTATCGTGANGATGCGTCATCG
+
"EH?/-$15D75<74(.B9FFFB9">80-6$?9%;!%(*+E>$D7%C#&14,;4%!#5?55F>6&H9(@;:E<C60@2H/&(D"5&E"<+).)*4<,+D*.A,88<+##B/;9D+3<:1!=A.8%+*2@E40>17:#$#";B2-.1==&4C<%G)(B?-?(A>,6!!A#".40D&3<F@)ACF+:%))H.*GE,$96E:D6@F24H6CC43?&A7DF,68%)7D8!AA:0C32($
@r3717
NTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTNACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCG
+
#H*#0/>(2B2@>;2&,9BE85(.;CE)13.;((05;ED1A9G<<.G+4;@5C(2*D=?)G627-(#79.A#7,>6GB0*'9DGE'A(2'@35A49)("'AAH,<&C%HA"5#BD>'E.91'=75$.#:*)=/=7E0C1(B<5$<*0-G/AC!+A3>6"/6.!9"'7'H7++,5-B1>A9%91">&*F.0F7)>B645-(+6-5"!5?D1?=A)>H96,A-5#>&07!HG(("F@;6;A&(9@D5+6)BDGHCG*A8;680H*6,&%"!>#6/H8:B':BE.(/-)<'H$-+3?:58B>?0GHB.75";-47C726D/4<F2H=
@r3718
CNGGCCGAGGCNNNNNAANTGAAGAATNCCAGAGACTCNGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTA
+
))%(%"&'"''#%%$)+"'$*+%)'#*))&$&()%+$#))%('!#$")#')*'"$#"#"'(##)'))'(!+"'$!&+&'+$!+()(&"%%$&"+&!*&(&
@r3719
TCNAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGC
+
!%%F!1?8A<;FA$H*,&'7&."+.!D%*5'D=2;%(!?,.B3-.<8,!5BC<6,"#5A9H4=9H-(DE5EB3G
@r3720
AAATCATGGTTATGACGTCATTGNAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACT
+
<1>8.(("F.!E2"!/(%+?G:.3+,EE,74";4@C%B)6%-1,7'!+>#H6;E944&<(H5C81&('2:+4B"4D5$GB7@,86H)#%B
@r3721
NNCNNNANNAANAANNCTNANCACGATGCTTNANTNGNNNTNNNCNGGNTANNCCCTNNGNNCNGANCNNNNTCNNGTNNNGCNNNANANNNNA
+
$!"""#$$#!#""$!$#""!$!$#$#!$$"#$"!#!"$#"!!!#$"#$"#"#!###!"#"!!#$$$!!#"!$##!!$#""!!#"####$"##""
@r3722
NAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAACCACGCTGATTTACAGCGGCA
+
+'%*(&'%"%&"&+%")!)%+&(%$*%#+*(!%$&(*'#%)*"(*+(*+*"'#(('(&+'!$&!'#'$$#*%$*%$#)#"')*#'#%&+***!%'%%)*$
@r3723
GGCGTTCTCGCCCTCCGTCGCTGTCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCNCTTTGGTCATTCGC
+
9>4,9(+"6(0(%8)$"%DE1.#8+&EDF+=D4"5<FGE/:,D/C>'@0A8="(/&);H"&<F8>194B:'6>-9@,F0$)*2635EA1,-(AG-+.
@r3724
ATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATNACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTNTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCTTTTACCAGTTTCCGGCGTACCTTTGTCTCACNGNCAACCTGTGNCGCCG
+
#;@H;H$.ADC??0(6.>7*AC'D590.94-F$)8:8"A.;-4:,$"9<:D5%9E6H)8'F/?F/726C#-;-"-'/B3*7*H"'90:EG71%:AB0.E)#-#<9.C8G1:5,B4>-3@$1E@585'-'&'E:@<0%@;DD0;#+1!'6;)03<41?@&=='<E=B=/="E+A2D-32E&E<>*:@"1G0=:!*BC?*0(+9>-GH>+-=@3/#5H$!&@40=$67!8!!CH3(?+#B++:=40/'6&&5C='/A'&GE?#
@r3725
NGCAGCTTGATTACGGGCAAATCCCCCCGGTNAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCAC
+
!2$B56<H)98;6;=1$6A-2;G61801&%E07/!%)(/3C?(F=.@G((*6)(#>#)5@=4;H/9G)(#FH.-&*H?&<G7<#,/$@=G9!8C*FB@&200$?($*/1.$$'%,F:<HA,)</B=/
@r3726
CGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATNGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCNAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCNGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCC
+
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
@r3727
TACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTGGGATTNGGCAGAGACAGGCGAANCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCNGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAANATCCTGGCCAGCA
+
72/2DC:3%,,77*)<ADEHH"4/B.(+5BG/F3(%7"90F/%$>07*<6BE%8GB1=,%F74B&E</;(0,=BF!$CF1+4-F*#<,@.162&4@/B7,=5,-27"1;'(<)62A*;1<B&C.809G3'-D(:5BC)0&=&:(3><3:A/0E4"HD>*2+:-7H1G(2GD(%5'E?/=+GE0DH,C$70!;1
@r3728
CAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTNATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCACCGANCACGCCAGCATATCGANGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTNTTTAGCAGCGAAGCGTTTGATAAGCGAANCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGNGAAGTCGAGAAGGTCAC
+
5;'C!.44.869%&#8A:49.9;A+',=<08&FD&+-6?:/0:2ACD&=3(6&?8G499,,)7H"2&'3$5$D%FA:;414&FHE"08'8&A'.<))BG8);=067@?.B<850F%:4?*.7!4:#:A#:*)3B097@%6*:=#?.@=$2@'F5#.>-=&E4H2;6/$@?D(9B1!#E<G6E8*<<(=C"'429<2D$-3>F=2<0,4())G-'GA=B4+..@D@6ED&A><<G20#:/<+(#BD#>:E>6C;F$DE4,D(<*?=*(4B?+;!./;?4"=HC&,>2A66A';=.3$7=&/"6:399GBA8+(..-D:%E/H+:*F#8=C4@DB7</@1"25'D%1/H:1*!<G%+G9*/)A7"#%8@G"B%C8@*3
@r3729
NCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCNCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCNGNAGATTTCNGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCGTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCNTTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTTATAGGTAATGCCATAAGTCAGATCGGCTGAACTC
+
*(+)'%##+!&!&(%!'$$#)++!&")*+)$"*($#!"#!+*)!+%"#+&%#+&'+''!)"%&&+'+'$$$+%)%*'($"&!#!"+*&+%)!!++#&$$*)!*))$!&#%)')(!(*")(%+#+#"**$$)$'($%!+%"%+&*'')%#"$$')+)''$*#$)%%'*$('**+)%(*#)*!!*+'#(#*"'+!*)$%$!!'"+(*'*#"+$$"!#*%$#+$!"&&!*&)+$+!#))'*$*)#)()((!*)"%$%"#&")*#)'*)#)+*$+*('*(#!$%&%++#)+""!&'+%%#!*#$'!$*%#*!!!#$)$)*$$%'#&'#*&&%&!""!!!(+&#(("*!$&!("$*)+#**"#$'*&&*"$$)#*#+)&$$&("$&#()$'"'((
@r3730
CCGCTGTATTGCCGCGTCTGCGGGTTATAGTTNGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGAC
+
H)<<<8@,'92'9(9<#"<.EG(+;"13F833+=/HAE7.3#:6;3)!">:6!@&C;D?)8!+)*=(B&AA,4B?8B?1,=0@05@B)*!=2>8B?;<&.H.!CC8=#A$(<-C,6$9.D:<
@r3731
NNTNACCANAGTNGANGCCNGNNNNNGTNGNGTNAGNNNNNANANNTCANCNTGTNNACANGCGNNNCATNNNNCNGNCNCNNTNCNTNNNNGCNTTGNNNNNNTNNACCNGNNNAGCNTCTTNNGNCTNGNGCNCNACNTNNNNNGATNCGGNNGGTNNNANAANNNTNGNGGCNTNNNANNNTNGTNNTANNCNTAANGCNNGNACGTGGCNCCNNANTNACTANCNCNNNAAAGNNTNNNNTTTGCCGANCNNCNTCNTTCGCNCNGNNTNNNNTNNNAGNNNGANGTAC
+
"""!!!#!$!!"$$$#!!!$$$###"$"!$!"$!!!""!""!!$#!!"#$$!#$$"$"$$"#"$"#"$$#"!$"$$!##$!"!!"!#$#""$"#$#!"#!$#$#!""$!"!!#!!$$"""$"##!$"#!"#!$"!!#$!$$#####"#$"!"#!!$"$$$!$$#"$!$#$"!"#$"!!#$!""!###$""##$!"!"$"$##""#"$"$#"#!$##"$#!$!$#$$!"!$!###!"#!!!!"!!#""##$##!!!!""!"$!$"#$!$!"!""$"!!!#$##$""""#"#$!#
@r3732
TTGGTGGCGGCGCATCGCGTCAGGCGGTACANCCATTCAGGCCGCTGCGGCGAAATACCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTG
+
2+E@DE@E0:B7-$F667@G-3B/,%=@3BF3)5:(227G%#*214+DG%A*#D@8'.-EBB,H#<161D?AG.<%*#;!<=@56B1$HB;7$=?//*%!9-$DB:A:-B%@&=@@+H.1.>=1>"5A=G-7$+D$*7C75'%*7'D)-@(32F>#3)C&<"-H
@r3733
GAAACCNCATTCTGTACTTTCGTGCTGTCGCGGATCGCTGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGANCTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGACACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTNTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCNGCATACCAGGAAGGGCGNTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACNTCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTNACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAA
+
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
@r3734
CACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGATTCAGATCCACGGAGGNATCNTCAGCAGATTGTTCTTTATTCATTTTGTCNCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTCGTTACGCAACCAATACTATTAAGTGAAAACATTC
+
D/97*&'(-?+>A(,*H6;H40/&<>>A101*:2>@*3>83>BE+3D!/*7$)10@"!5A+:,/5BBF/*..%<4622-%C-3D*DG>C?0.)%:&?='8C#H0!7*2-F6&*@,0DE,"1-$-'@)=1%+,&,9@.826G$5;!)6$%:B!F'@64;&-)86'84.%94(-0+H2D1F2;C@<E:E>HFF(A@8;#;(724:$<*$AF0<7!.)"%9->=H:'#+EH59EC&'&;>0><(C"D:F7,(0')+,F?E5B>#&(?)H&?(%!@B&&7&2A+!,'5!G6D#"/,'2C8?@@G),,,;3917'B?3@;!D<32/?20.'70>G2($?&F/9$9<(2CH+?=A>7)&9)."C1@#4D="(.4G-=+
@r3735
NGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTCCGNCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCNCCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGNAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGANAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCANCGGTGCAGCACCTGACCGCAGANGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATTCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACA
+
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
@r3736
AAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTC
+
=/,-D#:'*)(#"=9'4(:8*E2D"4-FD00H+;=$A!6GF,E5
@r3737
TGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCNTTGCTTATCGATTTGTTGCAACGAACAGGTCACTATCCGTCAAAATAAAATCATTATTTGATTTCAA
+
!**$+'*%$!!%(*"*$!$&($$$)')*&!("*&*%#(##)&'+#*$)!!'##+(!(+'"!&&#"(*(''(*$#)&'%(#%"(*)*"&)!($#%++%"#%*&'*$%$*()%&*"+%*)'%!!#$#*!%$
@r3738
CGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACTGTTTCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTAGACATGACCTTCGTGAAAGCGGGTG
+
B#F->A#>GA"2)/?*H.*G5*F53&0BD693G3?+=:FG630,>0/($"0&-&!</42!C%2!(7CH?'.5H6C<2'E6.?=6.17=C$=='3:&*>B*=%*H3C323A:C#4/DGE:?%@'%C3BB+#1#=</F'>)!<53A)#<,+D(2BG1%4.;@921$#<$8C4&2+7G60)B/9H0B1'?;*.>D#B0@F2,B@@HA7/$E&@E)DE=%3?&#90"%';#&!0A"D)BG85?9D/4:,80++*!;&,)G&@08F<A/5F4AH71<1G:%D?3-<8B2.:)&GB1'8-H;B7=?5E5D!$4H?/,A#1%D&0H!94DG80.C)C9@!4BCHH'=9&@;1EBH.).(&00E#AE
@r3739
GAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTT
+
8*""7C1>F+@G)@,*2$(A>59)0<BG%F$(&3?!!::1/5>2,;D5&)2">;EGA38",!@3*F'E?"$.-G%1;6&D8F!%D<(7680C:;G%D
@r3740
GAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAAAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGNGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTNTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCAGTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTNCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTA
+
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
@r3741
ACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTNCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATNTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGNGTCTCATCTTTNTGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACA
+
#%>&4%:$1641)3A/938122'3'!,HCF%-H6)47!EG;("B%&H(-+:!-A)(115CF0$==*"**+?;'A+'+4:G9*05/C/9G/#0!&1B3/!A(,*AB";2,'.-%7&;7:0./H,(4()<C3)-F0#,<-:.+%;>/"C6-'5+12*<C/>?#E/D-")2"!?D!-3:$9.6B3=6>?-%1:0&6+&/1C6A&7=<<G#?103H+"9&H%C!&%<3&7#E4E6;?8"$?0=:&3$7#107)*$*4'D%=2*<30#F?H@>*0"823-:'$%!7(@,<!A#H.48-%EG;.$+6.C<93.2,4+!+05%?8.#$/:'GGCA6D-$-=C.CG4AH09-!E.3D?F7+-$/)1%*:"06"3@78%()%-))0)'7>FHH'/1?&G/&-76">;.)5H<H@.G*GAD*$!!57!0+160D;!.8#$9B-'$!=GG*/
@r3742
CGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCNTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGANGCAAAGGCGTCGGCTATTCAAGGATGCCATCAAGCGCAG
+
0636.0-A"#3(*1#"?)4(H()"7;-77>F.2D=>3?0/).0-/(%.#;=.3+1F-D087DHA3#9=HA'?1@-78=$<426'H#6F=8)(=*G*#C&A<G61B%B/AHD<$9BC+=3<<!&7B/5A)7<4/3/==@
@r3743
CNTCTCTTTCACTCCATCCGCGNTGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCNACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGG
+
'!:F<#GC:;%>A+1':%'3A8C#14?,;'>/C2($D7+B"03<8&0/>$63C/5C*+'+)60=<.!!"9:&)=AAF*7):""=*F#A6*+D.%55$E*E5@*=A11C+1.9E3=8:E6E2GF65#+0(@<*9.2'/E55*64AE<H%;12**:.6>))E>F.)BH<2!/<4?.!$3+F/EEC:B/1;3B1.?3;F)3"G$DDC'>*(1)8@;&5>2C9G&!)9"FB1(,A/?2<(DGA,(<2>%0++')C53-HF"=<-28#G%@34=*F',(DBE-5"D=E;&%9CGGA3/!$<4'6,%385G%#:<D'@$E=&9%@E%/*/8
@r3744
ATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCANATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTG
+
>@2.!6G%%1/&'8!<-).H=$B&7D3:<BD8GG5;)H<!7(/7)517H32FF.BF62D2+71A:$3BG@<:D*'0$&*.;2*A3D-A(:%=9-11;306E=+.,04/366<+9.&#>3<1-F4#'0>!(6!/(G<1'0F;+!<&=8)<E&#%'H))*A8".D##E?#)&&0%"DA'E(8GD@$#%#E)>:%FD7E;,@24
@r3745
NNTTCNCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATANACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACTAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTT
+
#)()&!++)*%))*(#&%'+#&'%%*#%#&&"$#"*+&)+&")"+$#+&'(&'""$'+(!)'%!)'#&)"&$("'%&"*")#'+#!"$""$$"++$+%(!+"(*(&%$#+#$#*$$%"$+#*)&("#$"$$&"*'*%%%)!"$(#!##'!%#!*!%*$&*%%+)$%++**''%#!"$&")$%+%"'''&+##$"&!&!'*+#())%!)&*$#$%&!'+
@r3746
TCAAACAGAAGTAGCACGCAGAATGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGNCGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATNTGCACGGATGCTACACGAACCTGATAAACAAACTGGATACGATTGGATTCGCCAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGCATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTNAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAGGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAACAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTA
+
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
@r3747
TCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCTGNTTGTATCCGGTAATGNTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAA
+
;6"8F+'%6CC8A289.#"#3G1@7&(>A=++B'1C;09CB3'=.6FD;'"C)D7;9*7-H643H!!C+/:3*C<1/&*2-B=23$11*AEE+8BE'D7BE5,0!)E.AC'B=+A#B(E7->BE6?30!/5?%B+5(49B2547?>,#$3:%0(5:E@#+&*)))*?#FE%=C!3;&'9*2/>%73*H*+5=#(&=,FDB:64E)!)=7#%*,G/3#<+!2>9;(+")%>$C-C>0!*>;-5=50,:D82A.0;$;@2;--:!9A?*A/.
@r3748
TGTGCCGGAAGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCT
+
)3,D5#2G;40%"61A=%?A24.B9E<=>/"?B43?D')C95A-0+?-:
@r3749
TGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTANCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATNTTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGC
+
C:5'#F6E#&&>)6./;:>57(@G=C&B+4<8EC/3H,":2-(;&4;<68E//,B-++9<)6-8?H+<E@C8B3G*:H@)#DC'E&,4D+E'5)'.+&&D+?*&70E!AC%2H)1-AE4$D+.:#=G">?E"6)E+5!,6HG29E!7E"(:>$D)HAF1'51-6A(<1FE+!:/7&<?;6+A84.E@?-.1F-G*E?=2+C'9:<-18<EH4:C*9+4A2!.%.B%F(21,%+8.)F%,;B0?@:*3H=12F=*:<'.>)3C&FC8G5C.A;9><8>43;,>G0F?-A.E?>G.&G5.D=,2D&3<@5B):$74C*+D39G:D8F5G,34+GC52#06E)79#62=>,
@r3750
GNNCNAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCCGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGNTCTTCGCGTCCGTGAGNNTCCTCACAGTTGAGGATCCCC
+
'"!#+$'(%*!#+(%(+#$#(&&+!!'"%&()%'&**"'$!'!%##$$$!&+(#!())'%*"(&+'(&"%('"+$)*%$#!*+!%$+*#*!#!()&*&$&$$%&#*$%*"%%'*'&)#&'%!'##)#$#%""*$"")!%##$'$*&(*'
@r3751
GATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACA
+
,#@)G0?1/=',<0/H<7H9A236*.@D!@."!>':4%D"-%.G5G2)!.5(.&);G8$F:F$'429*!/(>D51,-FE!,C&/G7;G/7.%C)=*.D#=FB+1&).%."2:$5E/27F2&+AH'@2;>G9;HF.#,25-";7=A?,;1:"-27;7C'=EA5$*0$@H.0:95*@;5E;;0$F!@(1+E'2%@D
@r3752
TCNANNATTTTAGGTGATATGTGGAAGAAGAATTTNAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGAGTA
+
'*"$(''*&*!)#+%"%$("&%(%!'($((&'")(!$+#%!#+")'%+#*"!$%''%*#+*!*"')!!"'((%+"+*%%$!$''&
@r3753
CGGNANTATTNGCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTCGACGGCATTNTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGTCCGTGTGCGTGACATAAAACCGGTATGGGCGCTCGCCAACGACANGAACTGCAGTGCAGGTCAGTTGNTTGCCAGTGCCGCCTCCNGGCGTCTGGTCATGCAGACCGCCCGGACAGGCTNCATCGGCGTCATGATGGNTCACAGTAATTACGNNGCTTCGGAGAAACNGGGTGTGGAAATCACGCTGATTTACAGCGCCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGCGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACNTGTTAACAGCACCGATGGGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGCATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTNGCAGGCTGACGTTACTGACGTGGTGCCAGCGAC
+
*"'$&$(*'&#"+%$$!$($#%!"&!%%%++%+%"+&$+*!*+#!%**#%&%')+*!"!%'(&'&%#%%%$#%$(('*)+%!&$"()&')$'!#!&!"%'*#*%$'!!#*%'%#'!*#))#'+&*)$#*(#%&'**!)"+(+&)'##+*#%%"(()%*!+$)"#*%+(+'")')$!)%+#"%"((#"+$$#*)%&&&!"(%#&)"%#%$'&$'&+(&&)%++#&!"#"%&&((%(%&+*'!%$$$'%!$))'"(+#)$(#+%!+!%+"(+$'!%'%$&&!'(!*)+"#'*#($#'!'$+#"'!(*+"+(##()%&(""!#"+!)+("*$%)#%%)+$%$'$()$)$!((#))#'%**%**$")&*$#&&#")$"$**)!&"*&+'%**((")**$$'*)*)$!'!"()"&%+'&!"!!(+$$'("+#'+)$+)!($*+$'')$'&*+))!&'&()!&))!$*#(+#+#($&#%++%!!*%'*)'%#**%'''"")##!*&%%&!&)'%&!&++%'%(**"&+#(&$%#%'%(%&$$$)+!)"&&+%&%&#')+)'%!&"%"%&!!%""!##$($&!&+&+%*+"%&!!+%($#!$$"+"+$!!)#)'*(!$*&!((&)+"''++$**""+)'$$'$&)#+!%!%$)%$*&'$')+$)+"*'()!$"+&&'+
@r3754
CAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAG
+
A9G*"/0C(?'3,':7F&1AG(0<8@+(57F&(D5!-0C*'/A<;E**2!-#?"/2@;=1?6'*C&H7-5.";:E6$G%$FG>;&
@r3755
NNTNNATCAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTANAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATANAAACAAACCCGCTTGAACATATTACGANGACATGCTTGTTTCATCAGGTGAAAA
+
##"!%&"*+$#$!$+!&#+$&#'""""*+%($++!+&&+)'$+#&#'"!$(&%*#"'%"%*)$"!"!"&*$*"+*+*"#*'#$#"#*$&(&*"#&')**#*&''#!())(''!&('&")**++(&$''*+(!!)*%"#$$)'*"(&%'*#(#&#'%+"$&#)+$+&(+#(*)")"(%%!"'!$*$)%)$#+&$!!"*+%#+
@r3756
NAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGTTGTGGTGAAANTCCCGATGGCGGTGCCGNTGACCACGGCGTTTTAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCNATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACNCCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGCATCCACGGGCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGTCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCC
+
"@6$%%0'(7#C;4%("E=-=9F4)0E((G=$D,9<9DHGH7<,6==@.;"#G.5$=CF>4.EE"2*%DH;!4!48H"CDB1+;5D%G7B!FFB"8#B6>'375BCC7??%;43"3&-$#@H?3<$+-?@5&',)E:GEGEAEF;&:?"@>G4@<8=A3;4'*C,)'BH.:+0C3CH><A***%AG##>-7.4...!?48-:98-63.,:6-GEC$&C2+3/G#?F.-;@?."?14+75!'G6:A+;5F?.:9D=02!!9$2ABG>;9)H.2>&E,(80$#G7!)5'8ABF)>*<#08B52)95F+@5*)G1:#<9E>G4+'D2B==$!65*#.8&G+1@(1E:-D+?.E66-*1EC2=H7/:$8"/,4BC8'@:+':"-2A'2FF43!,(&)FHG'B!)=+F(3/73D7$>%)02@'B4$#<,;?='9&+F0B)/')H9C"?G<EH"AAD<.;,(&$+:11#%9
@r3757
CGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCATTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGNCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCTGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCC
+
/>.=&E)4(B&F(%&%90&"%G4E'"@9?"*;$3:4%51*?7879/BF'69).<G!."/*B/3#*=#C5'5&G<G3"/=+!>5GC>3.&&@2F.#052#64E?3+A*H0+3D$$%!:.-=&"=.>:FD*F*$6&;E.=%A&5&/&A-)=%AAA)*<%2@:D/::+)=;/7"F16H2&?B/(3B6*/"5(D<+/;'/E8"7#&/?C#@..<?!2B/79,>5+,83&B.1%=CH$F&1F,90F@C%6E*%07):3;,$05'8++CEF.&1A?,(3$(.:9DG1C09+>2.F8<-',(4//4+DHD-<$30HH,,6GD,=9F/!8.:(
@r3758
GCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATA
+
0/GA?'))D8=@26=C7@;84:$&")27370E@@4>=?)'8H>""<>4C9A(!.31E&#20D30$>-B@(')B>H#DC+AB$
@r3759
AGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGTTAACCTGACAAAGGTTAAATTAGATAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTCTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAAT
+
8:!,0-,6+/2@1D;+D+?A;AFFG*G&&+B!B7/'C927FH=9;#97('=#"%:6'D0+-@=>6A!/B,G7D"+!/<4"98>@<@%/5"E(#'<;3H>DC,H7CH%##/@0153<.=2C1H?CD1B8;C/)F2<>';0,EA88C(-+;)(-E1?D(6HF-6HC"!.2&1#7G44+3.'E*E7D+*5%40B"A-$C*+4@%%8@&4$(,6(;",&48$?H,-"6#()&GG2*8#)@58:/
@r3760
ATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACACGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCNCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGTCATCAGCGTGGTCTGAGTGTGTTACNGAGGTTCGTNCGGCAACGGGCGTTTTAGTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTCTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTCCAAGTNAAACCGGTACATTGCCGTCGTTGTCGGCCGGGGATACCGGTGTGAGTNATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGNTGATGGCTTNCCTGGGGTTCGCCGCGTCGAAAANGAGCACCACAGTGATGACCGGGGAGGATANGTTTCACTATGAGAGCCTGCG
+
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
@r3761
TNACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACNTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGAT
+
+)"(%)"'!%*&')$')***$+')(''("!%*(&$+$)+$'(&+)(+''#(&(('$&)"$&*%+(!'*#&++*!'##&!#*'&&+%%&'"%")($*"%+''*"!+!+!""$*+&%(!%%")+%%!'+%&)
@r3762
CTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCGCAACCTGTNTCCATGAAAAC
+
6<6E3G8'-%*1H%#2F2%&89)%"8'%*5<7!%D('G2+EFC)<8+2E:&DG9%C+DH)<=/&/G?1AC>=>"*4$7-,'3F.$8<=D6,+B@:<3=8F<*H#'.>$%)'
@r3763
GNGTAACNAATTTACTATATGGTTTCTGATAAGAATCACTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCANCCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAAAAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGCCTAAGAATTCTCGCAATACGATAGAAAAACNAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTGCANCTTACANTGAAGAAAATGACATTGAGATTATTACAAATGAAAGTA
+
*"&%)'$"$+$%()+*#%#'#!$")!&$$%!'+!+$!*'''!")!(*!**%(*+#!$&($("'&*($#+&$&$$'%#$'&&$&&&$%++&!&#"!+)&#('#"+#*)!%#*&+#'$%+"&(+'$!$%#&&$!!+$&!$#!*))%&((+&'+#))*)*!#'(&)#&("(+*$)%%!*))*($$)('%)$"!%)*#*!!$"!&'#&$!"$&#&$')!%&(&$!&&+$*+)&%+*(&$))#"%*"((!++%")"$*"#%))'!#)!+"*)!##%#%#++$+%#')#%*"%!&"))&*##+*"$"')(&&$!)+*"(&&%#&*%"'"$)$(!%(#&&!*$')'"!&(""+(')%$$"##)!&!$#&#&+!%($!"&'*$'(*(!"")'+!"'"##&)(+%+'%#+(&*)()"("+!&#*#&"#)*$)"(*'+&'%&#$)%&&&'(+'(+#*&($##*%#*!&!%!#%'*'!'%)#*$*!'()!'$$!%(%!'+)"')'''#("!#+(
@r3764
CTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACANCCCCTGCAGTTTGATGAGTATNGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGNCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGANATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTNTGTNTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTACGTTTTCAACGGCCTGCTCAAGACCTTTTATG
+
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
@r3765
CAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACA
+
%*;-'<1*A"2:3@CA8"*;A75'75=..,6."H%G#BD!:)&%C$C99D&*03*C#&EEF%.A+$<4",?>;5E1)C2%7)()?:3=3/AB9)/D7H5F=+&9#59:+.8;-.!H&45*
@r3766
CATATCCCACAGACACCAGGNCATGTTGTTGCTATATGCCGGTTTAAACGTTCCGTCCCAAATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAA
+
,,2E1@+C5'=*0*1<&9(73/3%H>?G'%E..EA49?"$DH"1(ED/,+-("9+570AG$1)'.*G3;4)</<=,&(-0.)*B928&'4;.=6:/!E6)GBB4&2)C)8G9*6'B6.C3.<(..)3(+7=@'"-</,F736>!1G.&F8#E.,<71,5
@r3767
CCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATCATCGAGATAGCTNTCGTCATAGGACTCAGCGGTCNGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACANGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCG
+
<=4%8+>)<.)FF::)D8F,;:1,!&6?D=GF',4=30+:9-C1?1;?&!H94@(,D)4)?;A#-4H#B+28.2:+5=#2BH5@$"=,9C&!*33*,5'/%)B<@8!H7/<C=)7BH"7<4G,E'61F!#<)>A%@>?;>2C8'G3=*.C<4-*8H+">->H/5-!$2,@68C,G6E@(;A&%%E%:5$HC+:$;*","/G0<*E);"(G9:,7#?1F!"C-.'A0""#>F2DE,$3
@r3768
TCAACTANNTCTTTTNNNCAGCANGGGCAAGTATCGTTTCCACCGTACNTGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGT
+
(&)$(')$')!$"((!%$$($&#!'+))#*'(+'*'($&!)!+!$+$"*!*%!+%%"%'%&(%&('+&#**)!*"*&+*"*#(!)%+"$$%)&#&%!+&")"#&)(%$#
@r3769
NGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATG
+
"'HA./E,95$F%&8$@8)57,4"3H0+$)A!,;F%%E,8)%A<,%&):D*:.6,*"/>->/H828"FF)F;F),;G"D,G)G=6(BA3A?C==>&$?7DF8!<(;/B80;"(02@76%(->*5;99-59.4/H)!)/:FD<H/5:FH?%3C@?=EC.8?'7'2CG*:+?(5-!,ABC76B?D,!@H@$-!%0*.:DH07746)A?;FA3;+D.BB$='A3B(F5#-)C@+6+&)%67-$4)/'2<!+6)-,%+'1C;E>=@1,D3/$@BC$+AD,$HC
@r3770
ATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCNTCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCNTAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGNTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTCACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAG
+
B/&5&5>(:+1,D<'%D!1G>.FH3/:%?-7C4-!,,9104HEB+'7HA2*$;@*!@D93=.!33@=<>%*+5-+5D;#%A#)@7**2%99="6E74413($8A$<CB2F*(>*D5&D<.#D(>;)+?0)AG.H#AAG#-E?!42DDB/$#605)")'"C)&@B0$*4E;%5*)G1.$,;<5,!7&?B-;(-+$/:H*7&5E+F3#$4*E'$'%!.%(<+E='076+"04G$<,>#(9)(9B*74H@=27H@D%22439'HDA34<AC92D70?@D*D<-%FD@;5C&9=)/D.,79!@B>6#1,407#D>F'<?/(0=>>1H%*8%<'8&3+:D44<+<E4#H038#?$9*)!!1*+#<#D2C7=;$E3&9/E<"D26+2;-=2)?+!F0)2:8)4:C<D-ACBFH49(C)&B*-;1F>,.(2?-;.&)G)+C6D$C!?!(G;0>D:A+/G>=D0D!&B0&AD%=7"3F'?DGA.<BE=A;6D0#/HGDD;775&A)A6/#EA%G8C;6.1EC5A,;.<':*GA/DF85C2>BH>>G7=?H&.-F"=<6.;%>$68':"9)=@6D1=G$&-6=$%"4%3,)#<9FG>?$?F64%:&?"D.@12D+%2#9%?>'(16G#3!"F81D4,(;!"GD<>9?9-2&DB>@9?-"2#<G%;*.83B&:GFF0.B42G"+B%#(#+6,F+%9FFD#?9:7,@=<-?#+"#%&93#$07&"4?)$4"39=)%/9$>3DHA#C@/%!01DH)>#F%9!E%-B#&2'BGF'F6!*)B!F3#(?
@r3771
TACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGANAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCANCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTNATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTNCCCAGTAGTACTGCAAGAGGTTCCAAAATNCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCC
+
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
@r3772
GGGNTGNNCNNGTGTCNTNCAAGTNNNNGCNANATNTCGNCCANNNNANNNTTACNGGNTNTNTNNCNTGATANNNANTNNNTANANTCAGACANGTNAGNNNNGACNNTNNNNACAAANTANNAANTGATNNNACNNNTGCAAAGNNNNANGCCNNCTGCNNNTNNNGNNNAGGTATNGANNTNNAACANAATGANCNNCNGCTACGNNNCAACNATGNNNACGNNANNANANNATTTTANGANANTGTNCAAANANANATGCNACAAATGANGNGGGGAGANNCNTTTNCNNCNTNAANTNTCT
+
!$#"$#!"#$#!"$!!$"!!#$$$#!#"!#$$$$##$#!"$"!$"!"#$!"##!$"""#$!$#"!!!#$$$!$"$"#!"""$$$!#!##"!"$$!!"!##!"!"$$"##$$!"!$!#"#$#$""!$!$#$$!!#!""!$###$##!#""!$!!#$$#""$"""#"##"##$""$""!!#$#"$#$#!#"###$#$""#!#$$#!$#!!!"$!!$$""#!"!"#""!#!!"!#"!#"#$$$$$#$"$!""$!##$"#$!$!"$$$#""$#"$#$"$!"!$"$!$##"#""$"$"!"##!!##"$###
@r3773
AAATTCACTTCCGGCGTGAATGTTACTGANTCCCCGATCATCTATNGCGACGAAAGTATGCGTACCGCCTGCTCTCNCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTA
+
$)*&)&'+'+$!'))#+$*$+'))+!)"&(#+&%")"%%'+*'*%&*$'$(#$!"*&&("&+*%'#()%)'*"(*")+%('('!)$$"$(%'"#+"''+*$$")&!*'%#+!'%($!&+('#$+&#*+#&!)(#!(!'*#&*&)'&)**((!&&&'#+'+"""$+*#%&&('%*%+$")!++#!(#$$"#&#+)'$)+++"!"
@r3774
GCCACGCCGATTATCNCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATNCGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGAACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGNATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCNTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTANAGGCCGTGC
+
;&*,(&:G-07H%+.6C10>!*;:-321E,1G<$H#A%G%"B?A"""3,6:G1,(:<6H&3%E.E?);2FCF7@&(-%52,A.?%02)'.8;+)A./C1!50H91,!A-99<C"38"!:?F".G)71//G/9C!(DD+$$=/0$B<,70)(&H6:#2&A#(0#5#F&845%=8E":G%E2"<E(.:$F)>AD(/,E@;;?H8*8@">G(1A+'@:B&.4@;<?%C2)9E'/7=)<%:&7,?DD4:.@1H-+-$>A06(=)0AA.)-%!(&53/D">=.6//8F0@46>A+@)?6!E'$.7D/7,-)5H7+60!(%8F+F(:79CA"7FB><#3@>&3(E1E9<F;%309838->=?8&D*>5;$6-2?0D8?>A$D8.%EF>@,F$@.4F/8<$2B(78*-2G,H2(D1$-37+4FC18$"82%$10#72"2)'*$,=)A%#'<H6/&;968557/CF;1(.E/<FD.=5<@>HD33!?*FH35()-!.+=(-'&#F4?7;3)*?(#0<?8E</?G9F$GA"C3'!C597>!:6,B"3-"C=+!=H",01&5,6G?#4)FB4"))H;()A'>?H+G/'""#<)4:)="4B?+D,(&B5/5G=)+)&C@/<H)0)3?G(5("=5B(+;#
@r3775
TCANNCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATGTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGNTGCATGACNTGCCACCGGCCATTNTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGCACGCTGCCCCTTTTTACGACGCCTGCGGCGCGCAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTNTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACA
+
)"*&#+&!#*)'"(#$''')#$%+#%&%%)%'(+!!$&!')*+!***$('!#'*+$$!(+&*%$)'&)'$'!(#*'&*$"%&"*$$!&+#$!*&"(&$&+%(&"$($'#&%()(+"(!(&(*#)""'($%")())!$*)"#"+*%$#*"(#$'+"'!#%&+&!#+*!(!+&*!"&&")&')'!*%"!'($)+)#+)%+(&+!+##)$%+)+)&)%$(+*(#+(&#!$!$*&''$$#"'%*#$)("+&!''%(!*#!+&"&"+$%"'"$*(""!('&#"%!(#$&#!##*+(+''"#*!)(""!$$&)$'(*!"!#%'(&%"%)#'#!&+(&((+(!))+#'')'$)$#+!#+!+"!('%)'%&)(!!%$$'*))
@r3776
CGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGNTATCACCACNATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGNAATGCCACAGCGTCCTGACTT
+
%+&(&''%%&"&$+''%%+*&#")&++"+($(()"(#+#*&$*&!&&*+!)'%*+!'"%!($!"($!*"#%)"!$*!(#(*$*#("')""#)(#+)+%"))#$%&!!*+*%#+%+#&)%&+'*''#')!$*)&%("()!'
@r3777
GAGACCCATCGGAAGACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTT
+
&&!&+(%$#&'#+&++(#%""*("&"'$"%%"!!*&&')%'&+&)"))&((#*)")!!*%#$(")&
@r3778
NGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGNCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGANAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCANCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGCGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTNGAACTGATGGTGGAAGAGGTGGCGNGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATG
+
!7%(3B'#H*#F5/<.","0.382>.0=:B2G&::%=3**A$1@5D'6:72#3*%C=0%-3E>8=9F)/$)6<E,$;$)DF.EB$3/'G%(608"<<C$4(E+.3-8B9"(:=$=--'H72(D.#G'+?&5C5>9;5)B);78(*G!;$6!5-3B#1B*A0'D-6%*%3BG?(&FDB2H,-/&4<D-A/F,F9+9,F'%=-A"GF8&*2@-?=$D*7:'%:HG$BH(14%H0$;7+&?=<./D6?%*6H&&64%=21!E&(/31H+G-1=%7HB'F3:'5:(A?>H*(&!2)#.=8G?,B5F*@!%<A%A><.B$)3*(?29D@;D3,F8%6?%E=(.)4F-#-$1"2(:41=8:)038+,?!@0F2=>4"5=3A:)22)==8C*">D#D&1H+D+<01G3"C9'54-=9=G.G10)9H6B>:")EF0A(0@/)F2974?D83&D0.
@r3779
ATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACNCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGC
+
%B<C8G)+H(.H>&#.D-,5(4-26D!%2(A)22H'$;1H(.H%?A+#6#+"$7<B99D@(3D>?<30".3/*=7(=!B(>0416CG5C:)H@88,03::<'";#B,H1HC%F?<$56"9H/6H1:12(0'0;2C-3;)G.#3H,&6"<?@>A?$G;+)&F&:+$"C>&:")3>,EDE7E=*<?5@*43?"/1A@H*G?G&+)-F37@,*4('9*D+@.&03.7/>$="?(
@r3780
TTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTNCGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCC
+
"9C/=-@+@0A'A#@>9DEB9&&:1254C&<95?@6:$C<7,617(7*4=5-:'>0%-B;+1"*5.''G'9F;EHB$641/-6C:D99:1+7(4$D4.*)";D#32!A'1!<@BD1,5%+E3%(1*)G$;%E=:&BD<)%E@::2:,45,B/()FB.1.*@%%0)9!=104G62*0/C#!;>>H6E*(%<5FB?6228=$%<EC.$5<3%>5*5.)H<!D:0(>+C:66@?D$A(12GAG'9!=+)@)A9B7*5G'C4)!@?@2<>):G+%$:.2?%CA&6';A'6@B%1&3&5412)=25/1-'E78.;5('H6';'<(5C:*99<):>:837/<@*B!6F&6C'>)")*B514,:6;62H7C/DEC,EC%2;=5)FAB&0$9E@F$)&1&!$+7)%=)746#"(7/97+,EE6+E!9;F#/HG,A-C#/.$015F,<25!F=/.+;8#$'F/C798
@r3781
CCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCNGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACC
+
,(9,(-?B@F+:493,!6B!=4$61F5:08=22:73&?*2)C2,/5?-BF),B$:#G15"&3,!C7D(*F8+?C:&'"&*#*+#DBE!):>!>?
@r3782
GCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACNGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTCATGAAGGCTCCGGCAGT
+
?B-BF6#+$!@EG4F'!<(80?9$:$C,F7G::/&1B%A%5@>=AGG,7".H1#%4;/;2H>=(4/D7:/1#EBF.8>@?90!H7C.07"%
@r3783
TTTGATATAAATCAGCAACAAAACACAAGGAGGTCAGACCAGNTTGAAACGATAAAAACGATAATGCAAACTACGNGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAANTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATT
+
6C?>BC!:B$4:1/*!92?7$HC5?%3?H058H1E695<FF4#DD8,<4H#4B+0+68?@B0G/:<A;FDG7F9:,!C=>?9&:.#.<;*B-B$0&;'(/F(5*62+-,,$(/'))(G+<047B)8+1='.H9!@F//1(1*-AC=;/B21&'!0-*F5H";@,6HB2&'G+?#+.D<?,!G:-=76E(4*$5&&D#6',FH2!!+<&
@r3784
TCTGGNTGCCCTGTGCCACAAACATCGGCGTTTCATTCCCGTTNGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGGTNAGGCCAATACCCGCGACATAATGTTTGCCTTC
+
,:=+E&-A&5,G*GAF4+;.@!((/1=A+-$:$;DH7!'95">81C';&#G?)@97'6BF!*(E=#E92B..%6;$4G/EE5@=%2D#=+/34F=.F@7*#("+*,<9"1=<#;>14G9D*-117(9*=G=405A-F2;1$/B:?-**9AG7)&
@r3785
CCCGCTTCTTTGCATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGTTCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTC
+
<-E/==>B0=@**&1B6G.?9GG6?+0'3B<,D@HG?%A-=**FH,9;H-C9D8&+A&9H14:$(:<04G%0A&)8<&="EB;E334G>+-?A@(?5)DE%>->@+2;C*1"8C;=5:.5@D+@>E68H;;+$<=+!3F..9.=(&)&@,E&!:+'<3#FFB,*D"#@4E>0::542,$2>+AD:-:A@;?G+8%B"1AB/)4'"48$E3.DED$$'&H(?@'-<A81/>$5>)2-7GA2-49EA>,7=65<'G<E/C%251'6@6-=;G="8&?$1;/F)':<5#583<,22G6:E89+B*43G>?3<>0:=6'3=AC#G.B00D<737E6FD#+B*<C%<"E3D:8(,C35*?+;H0F3;/44%$$8+0)#B%>3:1/78>-5?2&$$6
@r3786
NGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAANAGGCCACCCTGCAATGGCATATTGCATGGTGTGGTCNTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATANTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTNGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAACATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGANTCTGANCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAA
+
)1(E&GGC51(@D!;B&B!#;"2A!@A%,.6.:1',,F0#92(,2$189'"3>-E%7E2B4&552&=(;8,G?H5>D;4F<<?(6.=$3@,&$H>#+8B,9%+95,.B//A2G"@;%77(58<;FH%D>G+FG79<>"D-B$7&"@;</$.-,*0&%ADHGF*D4(@6)3!$36B;-739;G3>@@G;'90)8+H,#;?@.3:4!4929?%?=&>A#A.':+)5,#%2(+5AD"0/53/16+(G?*(E/98))!:A@C>3)D)9@F?2HE)D-F0(!D$H5@B"C*11$H<C;&/CH8B0-)7E5'81'<#3=0:A>96!4@+F<+H%3)2)%D-A2G593"9>3-)-*8A.96%(,F4-)':5"8:+$*B<@41D#5+:4**.-3?6?'<0)8F;D8&2G=-H$<**$3=3)%ED;('1#A5%?*?,#>B?3CB4$-4A:*"-
@r3787
AGTTGCGTGANGGGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGNGTNTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTNACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCTCGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGNCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTNAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCNGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGNCTGGTNCAGNCAAAGGCATCCNTCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCGCCCAGCCGTTGTTCGGGTCAATCCAGTTCACNTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGC
+
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
@r3788
GGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCANATA
+
E?>GB$7A>H')=$%C4HB.094*'22<4>'C-D'DB?;CB54GG"G6G'G>%:-*7C6/%2';98.)%HD#HF+H3@?:E*.>%
@r3789
GCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCNTCCTTTTGATCGCCAGAT
+
F?:<</-*4?E4G5&-"*B(E?H.!;%/=)C46%18)2$)F.>G54/)$/5H/9),A-)15+;H/5%)77C#0)%/,4D,*
@r3790
AGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCANATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATNNCGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGNATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCANCACCNGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATNACCTTTAAATGCCGTCNGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCANTNCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTTTGAAAATATCGCCCGCGAAATGCTGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGAGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGNTGTGCTCCTTATTTATACATNACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACNTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGNAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCA
+
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
@r3791
TNTATGGAAGAAGAATTTGAAGAGTTCGAAGAGAATCCTCANGATGTGATGGAACNATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAACCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACCCTGCATTGTGTTCATTCCAACGAGTGAATACACGGAGCNATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGNTTATTGGAAATCATCTTTGCCCTCCAGTGTGAGGGCGATTTTTNATCTGTGAGGATATGAACAGATGTCAAACATCAAANAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAANTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGNGTGAGTTCGACTGGAANGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATAACTCTCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAGTAANGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATNTTTACTTNAACGAATCNCCCGTAAAT
+
))+("!""!%"#!&+)'!#*$(%'*$%&!$"*)'#**(")*!")((($#*&+%!(!$#+%*'$+)*)&)'%%*%")&*$)!+"+!#&$*"'+'%$%$*+"'##%!#(#((+#*)'*)&+'&!+'$+()*#!*#+++#&)#"+''(%#(%(&##*""$#*#)##)&#&)&*&"$)!#+%(#$**!*%"(#)**+""#!)('!+!#')#)#%&&!"##+#%())*%"*%)''!*%'#*"!'"+'!''&*)")(%!(*$$()+&!"!*"(*%**!&&&"+"*&"%#&!'(+*"%"&*))!"!'(%)&)&!&$#+(!#'+'#"($)%#&&'"#)"))*))$!(+)"%+%"&$$'("+$$!'+*#&$*%""("#)*(+(&"(+"'+%$**"%(+$'!"%##)#'!))#)+)#$$&!*+*$+!!$&(&&")%'*&(#*((%+'#")"""#%%+%$#%&%"$!&!!+'(#$%(+%+"$(+$)**)$"+'!$''!#"&'"##")+&$&&'(+&""!$+*!&%!(#!!'"*!#("*!%)*"()!*$&*)#)"$(%""$%#!&($$'++*$#)%!"&!(%&%("+"#&$'$$*)"&#%!('!)(%*)#!&+%#))$#$!&)$"$%$$"##&(!#$%'*'*""+)(#(#'!!%+*)(%')$+)+*)#%+&''$%'**("&+$%+%!'("&#&"&*(**'+%'%(&)#''&%&%#+&#!$$*%'(#+!"'"()!%(#("#"&(")%&*%$!)'+#'+*'(("&*'*(%%#)%##+&%*")%''$)!!!&&'%%'+#"%#(*&(!*)+#'!%$%"#%)%'$(&)!#$%*'!"()(()*+#'#(+%('($!*$%")"!')%$"%!()*#)#%)!(+'(*'$$)%&"!(*'$%&*&$$&)%*'$$'"+!*!'$%(!*%'+'#%+$+'!##!+(%"#$)!*&&%#()))+$*&%+"*$&(+)'"$%#%#*$#&##"
@r3792
GGANATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGC
+
62,5B4!H7/?H*63>(!=7A8=).C;.57&E'57G$,#4!G1;A8/06;:'4&$8>(1;:@:1"2!%-D=7!C1/$<G!$A%<:A+:4.B40CC7A**33</GA.!$"?C2-1*FD@6%/(8;E,-8"A*-
@r3793
CGTTCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGACATTAACATAGTAGTCAATGCTNTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATANAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAAGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATCACNGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTAC
+
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
@r3794
ACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGNGGTGTTTTTACNTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCATTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGNTTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAACGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAANGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACATTTTTACAGAAAGAACAACAATATANAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGNACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTNTCGCAGTAGATGAGGTACACCAAGCTATTCATCACTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCNGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTANCAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAANGAANCTCTTTCGTAAAAGTTATAAGGAAATCTAGTTCAACCNCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTANTGGAAAAGAGTTATGTATCAGTGNCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTA
+
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
@r3795
NGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTNTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTGCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGGGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGNATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGNGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGNTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGNCAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATNGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGG
+
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
@r3796
GTANNCNGNTCNANNNTTGNGGGNGGNTNTGGCTNCGNGCNCNNNNNNTNNTNTGNNCCCNACTCNGNNANGANATCNNGGANGATNTANNNGNCCCNNCGNGNNNCATTNNNAGCNNNANCC
+
#$##$$"$$!"$!"!#!!!!#$!!!!!$"$$!"$"""$"$#""$!"#!####"""$$!#$"$$$#!!!$!#$#!!#!#$$"##"!!#""!$!!$"##!!!"#"!!$#$#!"$"!"$""!#"#$
@r3797
CGCACCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCNTCCTGCGATCCCTT
+
21*,/5+E)*.6*D6%C1$E3&G,0;C#.33*?@)"",B70<.,E)*CFE-0*)(D82F:C5&:.5+0;4#F
@r3798
NCGNTANAAANGTNNAGTNCNGATGANNNNANTANCATNAGCTNNNNAGNNGGNNNNGAGNCANAGNCNANCTNNNNGNNNCANANNTNNNANNNGTNNGTNTCNNNTNANNTGTNANNTTATNTNGNNNNG
+
$#"!$$$"!""#!#$#$""$!"###!!!$"$!$"!#$#!$$$!#$"#$!#!!##!"$#!!""$"#$!!!#!!#!"""!!"!$#!#$#!$#!$#"#""!"#!$"##"!$"$""##$$!"!"!!"!!!#$!!"#
@r3799
GTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTNAATCCNGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGNCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTNCAGGTGATGCGNGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACNNCGCCCATTTNTCCANATCCGCCGCACCNAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATNCGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGNCCAGTGCCGTGTTCGGGTAGCACTGTTTCACNTCGATGATTTCAGTGTATGACAACCAGAGCGTTTNGTTCTNCAGCNGGTCTGNGGTGCTGTCCGGCGNCATCCTGCGCATCCGGATATTAAACGGGCNCGGCGNCANGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTNAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACNTAA
+
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
@r3800
AATATATGCTTTCCATTNCATCGGGAAANAGNTTTGTTCAACANACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTTAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACNTTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTNAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTACGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTNTGATAGGTTNCATGCTAGATGCTGATATATTTTNGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGNTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTCTTATCATTCATNATGTATTAAAATTAGAGTTGTAGCTTGGCTCTGCTAACACGTTGCTCA
+
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
@r3801
TGAANATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATNTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTCCCTTTACCAGTTTCCGGCGTACCTTTGTCTCANGGGCAACCTGTGACGCCGAGTGCGATATNGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGC
+
&*&'()(+*#')&)&)+'!+'$")'%)"!+*)$(%(!%+(&!)(+""!*#!+)"!'(+&'!)%&)()((&$#"!$&(*("$)%(!")&#+%*+*"+!('"*+&&"&%$+$*#$(#&(&&"!$%'!"*!"+##"()$(!'#"+#("!')**&%)%"+%%'&!"%)&#+"!+%*"&#"&''*#"+")$#$#$&+$)#**)$"%#$*'*!+&+&$*&"'")"'"$(!+$$"#*)&&**&)''%#'"%!(*#("#&(!*#(((#"%(!#)$%$%%("*"#!)$+'&+
@r3802
TTTTGTTGACTTCCATTGTTCNTTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCNAAAAAGCCTCG
+
,)03G!(E4=.)6;2*HB.6G(-#"=?/9.1/-5@"!./;0G',9;E,'=A!4AHE<&31*;4*F.'5>".)
@r3803
NNGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACNATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAG
+
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
@r3804
NTNGCGNCCATCCGGGACTGCAGTGTCTCCCGGACGTNATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTNTGGCTGCCGCTGTAAATCAGNGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTNTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGNACACGGGCGATTNAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCATGTCCATATCGAGCAGAATGNCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTNACCGGTCATCCCCGA
+
#%!##&+)*(!+&'()#$"(')+"""&$!#%'')+)'"(!##%*%"#(+%)!+$)!%##!$*#$(##(&""!(%'+(%&$!!+(+%*+'#+"&*#%'*%#&)($$(#**(')!)$)'%#(&$*+#!%#")(+('*+%)#$"%#&)$*(+&)#*%$$+!(+*!($%*+!!(()("%#(%+*')#*(+*')+)#!%$(#$*%+#!%''))")%!''#'++#&&(")!(*&*!!+''''')!*$!)+#)''($%)(+#!)'&$''%#$*)'*!%"%#$*&($()("##!)*&&+()$)(*+$*'%))"%")(%#""$+"($&$%('%(!$&!"#&$+++(%&&+')"!$"%$'(!!#%""!*)'$)+"#!#*))##*"*'(!$!*%%"&'"(&()$*#&'&##+$&("$#(+#)!(*'
@r3805
AACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGNACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGNCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAANGAGGCAATCATT
+
B/4&4B1E!5/2E!680.<5B7%$:99H<%/;;C)'/$0/=FB%AC/C4E(+8.'0BF+(:%+-0??F;"!4+C64&,=C!H%>HD7$"&:;&+$/?.='#2#F59?0A.%G@;747!>%2&*3C-+61&&$+A-+D<'4$%.BCB<FB-%,F"")2!9F=E->-4@!<#:"46'#.%;(B*2#D/+!%CAF.3B%!:1+<7;B>+),G/':H+9+B(,*3+.!4+#5!!B@@G'%F32&>?B(%,C4#CFH;E#:5CG9'F7<",$=3=;D&8H-9)37/7@?@;+!..2@0=H?FF%-0H;;83&BB8C3<3(>;37@3-C0E3#+<C.@0918)-)5<71/?@%$@8H>6&-D#2>
@r3806
AACATATTTTTTATCTTTGCTCACCAGNTCGANGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAATGAACCAGCCACCGCCATTAAGTAGCCAGTGATTAACGTTTCCACGCTCTGANAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGG
+
D8G)5#H4;/$0F$:7""<"'>G(@F5:'#<%7.)E,42&$9+9=?,)<G"8&9$#G0&1&#<)'$54)C>,1E,7>7(F%&(/)C?"61&3DC2#+84%&C0$#62?5-",$8.A3;;F*=A?$&*#9'.<5,D%"?1D&G3175<E4&3*.<9)H$#6B!F:91<A6H816+02!G"&B.;*%#E.>+5E$BD95,@"7/1BC*;:>!
@r3807
CGATATCCCGTATCTGCTGGGATACTGGCGGAATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCNGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAAC
+
+"#"%$#**%&'!&#$%(!'+''*!'#&(%$)*(+++!)%!#*'!')"('+"$)&*'"$%)##*'!!((*!*")+)'+"%))""$"%)$#&%(*()+&()'%!)&"$++*)"+%&&+!*$%)#(%!!!++*(+'&#*+*$!$#'!+(*+#&*(*!+&(%($#&!&+$!*((&("$*!%&(*&#$!%%+!*(!%$))&"('#%'!)$)
@r3808
ANTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACTATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGNTAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCA
+
*!<=..#=;$2#*)G=3?/GGCC8F453G5?:$$-*;0?;E%/$:A.F+>9D6'A@%(";?CC@@G5:@0D$BE8>(,%B!FAF>EB%'%E#B;7G*57.),F,*(B(,-&GC2H=)7*G!.14?3718E)*E$A(F3*./?<.-?-%:23052<D;!:2F6#=626>:1;?%<*.3@=3<6H)FD6E6;*6@D/A$&>&F8!!F031F&,$B>GC
@r3809
AAGAAACCATTAACACAAGAGCAGCTTGAGGNCGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGA
+
$/D4)9D2.<D*HG9249.*#E?;D@2B&96'+>=B;5'(B838"%'%@?&-160&H:?@A-D?)4*A=4*.-:&*7EE165!HD?F.!4'1E4-F:0?(,5/GE:AB@CED3G2
@r3810
TTTATTGAGTCGGTATTCAGGGTCTGACCAGNAATTATTAATCTAGNGAAGTTTTTCCTCTTTCATTACGTCATNGTCGATTTCAATTNCTATTGATGCTTTCCAGTCGTAATCAATGACGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACANATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAANCAGAACAAGTCGGCTCNTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTACCAGGCAGCTTTGTTGTTCTGTTTANCAAGTTCTCTGACAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGNGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGNACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGAGTTGGACTTCTGCTTTTAAGCCCAGANAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCANGTTTTAGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTGACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATGTCGCGGATGAAGCAACGCGG
+
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
@r3811
CACCACCGAGCACCATAGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCNGTTAACCCGGACGTGCTGACGTCCCNCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGT
+
-EG*=1@=".#B+<H9HD<3,"4#-G@2CD0.*"ACAF9"F1D>=#H><)8BH296::2B010F=319;;H+'=52#10#";=:9(,.'C<A-*#BAD/.-!%@(;'F":2()G<-930BG#H=)&?;E<=+7$2B?;$3.62>:8C?./@%C>4.'ED&,+@0?"$>7;.'2:$E<B>67+2D=8:!70>$'?49$A1*";0.=CC:E$.F25<(&.H:C;?:)(B75B,C%1FA7E-/,+"D7C7A36(G*'#$4'#*!*;.4C8C&A@9B3'!=(?2'D1A'*.B%?G)C(AG;+C,@!DH0=&65?+><?#9&0"#(#F9F4B%(0CF!5/"CG2*<$?G9#5:H$'2-""?H-A6*B)20AC6/,!%6HD<(-8<4/H5??C<-/,G#7#3!CC<!%=3=8CB,)?;7820D*2""&.4;!F$:5<:9CB-,.(D;*,,B5@A(4G#B2!%;B@
@r3812
TCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGNTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGAT
+
36B;0:?A93A&-9?4@&=/G0;/3!>/F25:(9-9:F'):'2-G/G73=8G6<HFG=8%$'D@<4G=/&;09/2D$8'10,HE!669@GA3'&96>6)B6$9.<((%B63H9)#&!C=%,1=9-E%3:?2;F"1)@"'9?86;'>%AHCD+)&B37.F&.
@r3813
ATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAA
+
+&&+$(*!(&%)&+(((+)(%")%&'+*'+"#"$!&#(!''"
@r3814
AACTAGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTNTTTGTCTGCNCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTNGCTTTGGTGCTGTGT
+
E(C&.++&>?"6>"4D"!5GF/:9&/16,8:A-D!#$9D(;6?8.//17A9:8*$&(>CB>3D'B"*"*C=?0%D5D?:$&$(/%2=?0)C)1!&F3F4<9-=3!<?>:76E:C%:7C0(06G;A(0"7;GG<%
@r3815
TACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACNTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATNACTCACACNGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTNTAATATAACGCTCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCGGTTTCTTAATCACCANAACCTGCACATCGCTGGCAAACGTATACGGCGGAATANCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTNACAGTACGCTTACNTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGNTGACAGTACGGGTACCTGACGGCCAGNCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTANAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCNCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGACAAGGCCGGAGGATGGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAACAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTCACAGCCCACATGGCGTTCCACTTATCACTNGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTT
+
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
@r3816
TCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTCGGANTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTGTGTCGGTGATACTTCGCCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACNATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCNTGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTAC
+
(?)C/#E.2&><@/'F0.#";D2@#,08)'C4.05;-B)B'2>B96#$(6.A#$*;>H+9<?A12(;76BB-H0+65E-(4?+/D:%7<H/46@6$A6&6D(814,C8>3"8*?(1:(H?/H/3G!3A0%#F9(A*+'.,G5G-E12GEC!/@G6-A)<G@1A0;'/-BGCE$AH@>%A"<G<((97*9-'$81(:>.60+((&8#>40AB9#@G9.&=D?@90)B.5%;$6'#2BB(4+E>&H9CG&=%E%G4:A"9(E*4"-5(DF0EG59=:)C";':CG!4;/6)#GGB/G(=D28D45D+)B+A*!(FH>3E;,%7$"!)>=>4F%3$*.&5GD$0&),8.<#55@E,)=#@=;4"A&*:7A)-1E+C'4
@r3817
AATNCTCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACNTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGTTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTCAGAGCCTGCATAACTGTTTCGGTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGGTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGNCACGAACAAANCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTNCTAATTTAATAGAGNAAATCCCCTTATCGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAANGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGA
+
%%$#!%'+&)++'()$&!+++#'&')"%(*+'(%)%'#!$)($%+*##'$%&$#!($(()"')#((%###)#'$'&'(((#$*)'*%'"!%%$))#%$)'&%(**)'"&$&!&'+"%(&$%"(%&)!)+*+'+*)$!##$'*%(%+**#**"+)))$#(#*!*&'(%+'%'"##$&(*&)"!+""'$*#!!%&$!%!'*'%#()!!"$*#&!#!)&*#(($*"'"')"("$+"+#)''#(%$)!'"'!!+%+!""'%&&%$((+!#'))(#$"'(!+(&(*&"')"+&+$+++"&&*#!(('$+)+"$"&")%)+&%!#+!()&)%++(%&%!#&*'&#&'&())$&*!##)%")()%)'*(('&!()+##!()+)'*%(+)%+*)#!+#)!%$(!*!!(&&$#%$")!%(%+&%$+!)))'#&(#!!%*#)*'(#+&+%(+)%(&$*"#!'&"'$!*'''*&$+'!$*)'&%'#)"''%#&$''&#)))+)&!%%')!!%)'$*($+$*'+('&(+'(#!$+')&*)$**()$(#*$+&"$&**#(#"$$'&$("*"(('&'!('()%&'+(*)%"&$"&$&&("!($#+"*+&!%&)"&'#&')*!!+$))#+"+$%)!"#')$"$##&(+'+&'$*%()+'"((!('$*'+)"&('+#()%)$!!%!)#"+'*($))'%"$($)+!#(!')+++$*')'$(%&")'*%)"'&"#!'(!!%'(&'('&#!(+"#$'((((*&*'%"#)&'+&+%("+$(*
@r3818
AAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTGTTCCGATGGGTTACAAATATCCATTAACACAAAAGATATTACTATANCTTTGATAATTCATTACTATTTACTGAGANCATTCAGAACACTACACAAATCTTTCCACGCTAAATGATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTACTCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACTCNTTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTNGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTA
+
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
@r3819
TGTTTCATCGNTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCAATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATNAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTNCGTGGAGGCCANCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAANTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGANAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGNGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAG
+
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
@r3820
TGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAANTTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGA
+
;%DF'>2'/?E"&:$G)/"G-G4684#(C25.GEC@42,;!69'==9(9HAD5,</--*)))%<>&E&:>B5(1653)!B'=2,%02A!/&>(45"'.4@2#GD>(%66D$&(B:#-#4?3+;E==#A,&>'B4D;4)H:75)FAE$7'"@E":-9/#*#:-GC:98%%4
@r3821
TCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGNCATATAACAACCAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAGTTTATCAAGCAGCAGAATCATCACCATGTT
+
@B#D&(>0<:E5*;$@!D',2=-<19+:G);09)D4*36&*04@@70*"FA*)8#F)>%/"4,2++:1?>?/3:F(8=)%%E#&&##6?F=&9.9!%A/<??3#%9A<9>B?=G81;"0:69,%D74E;0$#/E($"@4*=F<:F$2%>)A7./"+'0>>>0<CDG4@6D"D-!)F$@
@r3822
ATTACTTTTATATCCGCAATGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGNTGATGCGGAAGGTTACCTGGATTTTTTNAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCNAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCNGCCANTCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTNGCGCAGGGCAACCAGATATTCATGAACGACGNGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGNCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAANAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCANGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGNTTCCNGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGAGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGACGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGT
+
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
@r3823
CATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACANGGTTTGTTGTTATATGGCCTTCAGCTANTNCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATNTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCANGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGACTNTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTNCTGAAAATAACTCAATGTTGGCCTGTATAGCTTNAGTGATTGCNATTCGCCTGTCTCTGCCTAATCCAAACCCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTGTATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGAATCGTGGAACAGNTACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCNGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCCCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGCTACGTCTGCATGTNCTTTCTGCGCCCATATCATCCAGNGGTCGTAGCAGTCGTTGATGCTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGNCTCGGAAGTGCATTTATCATCTCCATAAANCAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCGAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCANTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCNTCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCNCAACATTGATAACGCCCAATCTTTTNGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTGAACGGTATCAGCAATGTNTNTGTAAAGAAACAGTAAGATAATACTCAACCCGANGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGC
+
#+'(&$"'$'("**#!"$*&+*'+)+%)%(#+&$%"+%#")&#'#"$#%++!$)!((#'#$*!')++"$')'$"#!%$('"*#!*%+"#!&$$(+''####*$(+!')'$+&#%!('%&&%+&&!%&)"(+*!*#(%*%"'%$&$+&&!+'%)'(&$''$&&'$*#!"+!*'((%(!+$%&$%+("'&"!!)!)()+"$%"$$'#!"!(%"#)!+''#'&&!%'&$"'"()$+!($%'")'&(*&+%#'+%')'$$*(+)$("%%'%*&""!+'#'#+$$'((!*!&%*%'+"'%**%##'((&%)*)'"**)#('&++*#*(!)$'%%+!&+'*)'"&)*'&##"'"%&!#+(+'*"*!!'*$"!($%+'#+"&!"'**%'$(&)#$)%)*#!*+"+)!'$#')(*%&&+#"%$*$!"$'+&!%+#!$+&&+'*""+%&'"$%+"!+'"#!%%#*)&+($)#$"'")'$#"%%$"!)!%"$)&##%!!!!"*&&&*)*(&$%#(!#%#*!"**"#"#(*$+'('+*&$#!""'+%*+(***++*%")"*)&$%'())%+#!%$)()'"$)"#%"!('+'"(+!#$*!!($$"!$)*()(&""))'*#%!+'#%!#"*(!$#"*+&&!%%'$'#"**)*#)#$$!++!'*"*%*&+&"#%!!'+!#+%&$#$($#%*#+!)!!*"+%()$$$&!)%%*$(*"(+!!!**(#$"$*%(!$*))#**(*"#%$&!$$+++&*!#%+$(&'$*#+%*"$"!+*'#("*$)+)%())!%'+'(%(+'&*$)((#+')!+(&(+%'%*"$&*+#'+%*("'%"!')$)$**!'+(%*)')!#!$'&**+&!&*!%%$"'+*+'##""$#'%$*%$))"#$)'*+"&#!(''")$++"'(#$+#$)'%!")!*"()&")()%)$#!+%!)')+"''!!"%$++$((#(&(&"&&)'$"%!&)+"#"##'+"&!%#'+%)%(#('$"#"%)*"!)*%#(#*'$$*&&$!&'")#&"!)"'+(#"*%&"'$#$*'"*!%$#$')&(%++#!!)&+(!!#)(#*'+%(&!##")**&%$"%*$"!$%+!!$!#)+$$&$+%%!+%*')(($'"%)%#!'%!)+"#!#++'"(#+#"&#$!!%!'#"''%()""&!'%##$")!(##$!)!'#'%$('%"&$!(!)&*$%"'**#')+$(!#&)*!%%&"+)(#$%$$"!'""*)('!%%&!(&$%*&"'&&!#)"!'&$)+!)%'("+#'#**#!!"#&$'!!&#*('&'&!$*&%!!$%(*((&!()&#!""!$()('##)$$*+"+%!)(!#$#+$+++&%$%'#%+%*'&!#%!$$)#+!%#%"#*'+%#&$(*$)+!'$$&!"*'&(+(%+&&%)!"$')'!+'++#%"$$+%+(*!&'"##*&%"$*'!*#)#()#&('$+%)!)!(*#')&)($&&&#*!'%"*%(&%#&#$#&+&(&&)!"!*(*%!++&!$''$"$!#!'$$('!(')($)+((+&**)&&**&'$&($+!$)(
@r3824
GGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAANTCTTTCAGAAATTCATGGACAGTTCGCACGNGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTNTACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGGCCAATCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACNCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATNAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTGATTTACTATCACAAGATTAGTAGATGTCGTTNGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGNGCTTTCTTATGAAACCATTCTAAAAAATTATAATGNTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTANAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCAGAAGGTATGATNCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTNTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATNTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACA
+
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
@r3825
NTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAATATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGG
+
*-%-"94697<5(;%6$;81#+1;9:9()@"7<92C)3'@A06*;$6")3*9.5,G5G'2,FEE$8,H1)D@AG*C@G,AG6%-(E-6<9:.#053%$-B11GE;A))*7@;@(ADB7H*6$=3*&6%,+G,*F"$A)($"A9'5=D'=G+"B.A3>&.2H2$7)7$"241?9&+)3<&@'A?#;GCDG#&:<8D33;2960B:4::+/(H+&-'':9.9',#;8B!)AG6!'0,+09E@<*@E-G?"33+7/::=C5GF.:4D3H61)#C7>#.9%4$'5#<*/+-EB(G4"#6,$8%1%=:(0:%0*)5,"'"(+14/%2C'))29#A.<9"&3-#HE$H
@r3826
ACTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCNCGCATTGTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGNATCTTAAATTTGGCGACNAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCNCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGNGCTGGACTTTACTGATGCCGGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACGTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATNCGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAANTTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTC
+
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
@r3827
TACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGNAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCNATCAAAATGGAGAGTTTTATGACTAAAAAGCCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTTCAAACCGNAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAANACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATT
+
>7##<?:$A6?(1C58;>!.-D*!#(52B71!H'5F1A45F?$AG8/E7<BBCA-8:1,928>E2H2%*!G/(BD;$5+-A2"F8)'9G5/&A-//AE;&3%780E??4:B0&="EE3C6GHE,<==*6)6@AB)*5)%:/!<%D;,/5=#(!*BCD(<#!H>D+,4"F#,B,12:49C!<1/F+6;5(/H)4*B4=!03#,7;)#82'G!!@-34.4C+83066!&%4G#''*D&)E$,*-468E76@+DC7&"+3)2,7=B&9'(*(!<3?5GC</+HG;+04D</%0&A0E*G1,99+1*"<HA@?==B5B:7#$,#<2(AA@.CG".'/"0&+$/5+=/%3=C3(4%AFH2-+F$D-&&.1+91-81@4AFEA/GA3-58+A8-**#D6D=+5357/-#:*F&C>?%@3B$31&EF$E"9:&=:GH+B?A!)!-)9.<702=16H61>BE"8495-,38>C(H1:
@r3828
CNTCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCCGGATAATCTGGAGGCGACGGGGCTGNATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATNCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAATCCATCCGGTCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGATGGTATCAGGTACGGATTGCCGGNCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGAATTCCAGATTGTCCTGGGGGCTGCCGCCATCGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAANGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGA
+
!!&#+$&(**+!)+)%"+#!&**()#*)"*$""*)&+++"(&)&**'$*+)*"#""+$)'$%#"#&!)!"$#(##$$&!+!!+"$'#$#$'*!)'+&&!*##++!%"%*&&+)%*!(#+'#'()""!$$**%'&%&""!!#')#!%($!+'#"%'&&#!+)&"%'+#))*#+&%*!%$++((*)&$*"!%"*'$&%!&)'%&+$'!"++)!!")%*+&&%$"'&)!$!"$!$")!(%('"!''!&!!$#%(##*!%#&+""+&)("+$"&#+$)%)$)%%!'!#*&**+%#+#'(#)+%#)"$#*+%+$$!'$''%!#"&!!+(!'%#&"'*'))!$#(%!!''&'(#)(('(!)+(*)#!()'!("*!"&(%"'"&#&")(%$!%)(&$'$!!)+($+!'+!+(&()&+&*!(#"'&!$*)#%&&%**)'"+"(&&##$''*#!*!*(!*+$"!%*'$'$%#(#("')**!*(""!))'"%&((*&()("%'+**$+'$(&&)$"+#&"%&)!")!++($%%%"!$#"'&(%%#&'&!*$**+*'$)#'+')'&"*+$"+%%&"*!"#!#$'"!)'%'&'&!%"$(%+(!&)"$**(+%(*$("###!%#%)&"#)$%+$*#'(!#'%""&%!("#'(!!$%+!#+&"!+""$*!'&*&*&)$*$&&)$!$%*%'&%$%#%+')%'*&)&"'!&(+)*#+'$"!"$$*%"+#')#$*%+'++(&$&#$%!($#"%)+)%+!+'))*(#'(#'#('*"%)"&)'&)&$'(*)'#!"!%!
@r3829
TTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTT
+
5@19.&"-"G:46.!)6/&FB$D'!$4.2=4053F;E?'#H,CE>@$)7)7*199!'E3--6"2
@r3830
AATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGTAGGGCTTTACCTCT
+
--/G=>7;F#'#3F9):C2ABF,/?3:.A@$2&H+#936A42G=B1.44D0&=C!0<.E:2B3<)'C).6"+&8'-9).&+@3>:90;CFG>&B#,:;.H1)3&C==9<E-9<F(#9F7<"04<0<-)G
@r3831
CGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCC
+
2(::H3*(H88&.;+*"&<?(&D@-$5"5"B$*,+<!#7(-%8'>"6!7=B3+,,E<6F26"C5!H/'=!!2,$2>#@4:+A+>H=ADGEC)('=:+#B<GAD@E,"&$&82D00G99021?@,41B#,3CH'%<<6:-49D75.HC0.?;"?-*.4-'53*$*)?!>*8&C5+@?&*6E60A#D%=0+&<A>F94E6AE+)=<<9B(77':EG"3.:&27$A1G(3,.!D7;6>3<#F=;>B9A-6$@2/-&G+B.F.B>'?-B2"!:01+>8,.-8#./$6.>@@303%B8FA;.B#?;<?2?E
@r3832
TCGGGTCGCGCCATCTCACGCGCCAGTTTCAGGGCAAAACTCANCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGNCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTANGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACNGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCA
+
5@<+:#4?(=%E"7,7=FAFB%&<FH.E+)(@)F:E9H.;00A:#>.4<H07FH'05-1FB@@7"FG%!>,13*D96!G27=<C-=3:)#?C=+5#1:>16>AD"!&:)HH&5(,83+/680$;969*;'8%%>GF!/&A?/'!268?:=!.=:2FG341?&EGF27@53:2*C5.;DBDCD7E;:-6#;0.3=*).5.05#F/B=*4(F)>%7:$(5+8H@D+-7AH;(HC%(<G-#*GG29=;DA'$6)5*#,:GG'FC+G8?+C/=9"9CH5?3E-<>8E7(*8=.9@3(?9/=$C+E)2!?F1#@7"06>+*.G5>$:HG7G?1?"$+3C76F91HH?8$*)A-+2$)D)FA"!:0)$65!48CG61",B4%);E>/:+:)2
@r3833
TTCCNNGNNNTNANNNTCNCGNCGTNGNNNATNGTNCCGACTNNTTNCCGNANNNGCNANCGNNNCGNGNNNNGNAAANGGCGNTNNCANGGNANNGACATGNTCTATCACTAACA
+
#$#$"$#!!$#"#!#!"$!$$##"$"!#"!$$$!#$$$#$"#!!"$!$#"!!!!"""!#$$!$"##!$"""""!#"$#""##""$#"$$!#$"$!$"$$$!$!"#$!!!##!##!!
@r3834
TCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGACTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGAT
+
;?A0!A@#>:0?E!?4B1=D'D40B#-DDD1)+:4>!'44)FFF@?81H2D/H6+CD74/F>G*B+'%-#&(+#,G$2$6(476&=6'57?"
@r3835
ATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCNTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTTTAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAANAGCTTGAAATGATGAAGAGCTCTGTGTTTNTCTTCCTGCCTCCAGTTCGTCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTNCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATACGNATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAAT
+
03.F=3/E;6440592FBH69;D*.+(#B=217,@-4E++&;F@EBD!@45D$)&15>DD4&8.AD%:,<?55!@>FD=AE5&C"!0('>6@FFB"*D8E=%D(G,'H:=!@A=:&E*3#6C-CF3EB'($".*98F=<'-)97+H92-9-%7G"G#B%8@DGHAC$8)0>2FFB%1/:E9"B3.&G823&4$B'H/7.;G?!*:<://B30A<.<%..*!,9*'-$5A,=&??%$0'B2845$59(1,CFB<-DG?07,F98:74,+3'5&;;>.G6?4:6/E3&5?13C+(D"C;1+>)A9B@4:436>;C=21A=BB7/=/FD8;9E,#:3?:E(8#>>BA1%$68B.$29*.#*#"&=,+*;*%*G.#<C63+*:+F)(;E0E0F<6?"0#F8<*%;:D/FE4!(=29>$2="7;BDA(!GB='.&$+6?22!4!-(3BE'33'72?8H>5,/@$A@%H3#4A$)4!@"/<87F!:(;E<**'7#-72!6;$5%G7%2&#&!C#>G68C7)<1E2?,5==4G./=)B7<D.G<G@&*G(0:!&EC<).)F&7*8C$1//?)?8(?"74/@D8:79?(.3'@*?
@r3836
NGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGC
+
!C+/<2>25$0#"/9)D$9$CC@-(<G=,(:,E/+?.DBF.>#*/CA<>;-.,*"G:63?(877&>8)@3%H;');C1-1&>$'9.115
@r3837
GTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGAAAAGGGTGTTGCGCTG
+
9200882>66,13-/&"C3'=FF>B$=.'?)7=+&=&,@7:51&',(3.86/5')D3!G
@r3838
TCCTGACCGTGTGGNTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGCTTATTATGGGCCGCCACGACGATGAACAGNCGCTGCTGCGTGTGGATGAGGCCATCANTAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCAGCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGAT
+
>##&,;1;E$"8CH)35"E'><E6'$0-@"AE'@-2/146/<@/$E6'F/.>")8(/H+5(>/><-+>%!(16GB2;4"-9/>%4H+B"280%=670/5(B0*F6B:<:B,932+8+625*)+46+8',<<8-%1!E-"AD:D-".(80#"+B55;2>165?D;7!:6-672G>?D&A6=:CH2@B=5@&:-+@?:FH!8$H,.2&%>14:A".84*@1.0C:922712"F=2BDA3-A8B"E=E8+/B69,*:%;C:C+*>7A9!,)B!.-(/69*4/5F6%G53BH$+)C0AA!6EC.(4$"(*.,9)''D3&-G?86(B4!E$=&;:A0AD4<CE9">1><37(%/D/&B(*8A7F'+A%450'%7%)+%A.A$3H/G-EC(G80;
@r3839
CAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTACCTGANGCTAAAGCTGAANATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAANCAGTCTGTCAGTCAG
+
1A!H=);-9$6:+B=:CA7.89#:*5-/1:3'(D=*:7*/EF->.?ED?"(!:0&774)BA;)0%B(/$417+14'*@B"/D?0H6"4@8C,A<.>8>EE>5$,25>3>B2+7562/&?<!8-+,/'"#E-0A
@r3840
TAAACACAGTAGCCTGGATTTGTTCTATCAGTANTCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCT
+
;#(FC>C386G:3=*F=@G;-?=8EF>(BE<%G@=$%583@+5./?!,=GF)0*3342GC'5-?9D@&)GB%4;35?B,C2GA&:;74+,#.@44(C?>H8!$F.?/4'H.91>;*05C?8743*DC'1DF=#*@7$:C<?>@(4($E%=H++:%(9/;
@r3841
CAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCNTTATCGCCCNTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATCTGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTNACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAANTCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTCTACAGCGGTCAGGCGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACNCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACGNCTGGCTGCAGGTAACCCGGCATC
+
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
@r3842
CGCGTATATTGGCCTCAGCATGGAGGACACGTAGGAAGGCNAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATT
+
<?",AG*)=;#,@5C9/3>19H4*>D0+<?:D-H/<G(19'%39:%.B."-7D634830A!3<F"E()54>D&E3@(-:2G
@r3843
GCNGATTNGTNCGCGGATCNTAATTNCANNNCGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACNAGTTCGATGANTAACGGA
+
)&#')*)$%*")%&)&""'!((!'*%$#$)!!)'+&)&&+$#!'!$"!))#")(&)+#$"&((+$"(&+*'#"%(*'()!*(#&+%$+'')#&##*"'#&!)#$#)#&&!&($)!+$$"%&#((&"+"(%!(#
@r3844
TCTTTTCAGAGGGTATTTNAAATAAAAACATTAAGTTATGACGAAGNAGAACGGAAACGCCTTAAACCGGAAAATTTTNATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAANAAGAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTNACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGACTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGNCATTGAACAAGTCCCNTGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGNTTCTCTCATCTGCTTCTGCTTTCGCCACCATCACTTCCAGCTTTTGTNAAAGGGATGCGGCTAACTTATGAAATTCTTCGTCTGTTTCTNCTGGTATTGGCNCAANCCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCNTTCTTAACTCAACAGAAGATGCTTTGTGCATNCAGCCCCTCGTTTATTATTTATCTCC
+
083<,9F#+3#"*6:0(GDB91%7%F$G%5*9?'):?A%*41708@)4B!0$!1C-/:>>@,?.:"C34F)E1!HD.4H4HG(>D7241$!?;A0C3@0#G>#"HE,.?GEG#-!()8C68@)4EC3&+=345?9#6>(HD:%4HE#"D/4%2"C?7?!5("+EHF43>3%%(70$55.69'31:E?1@2'A')&=&0'&#H7<H1.=>5($6);@6*-F=.<8G&793F#*0</-;.D:-&+4=..F3'/$<5C.)/BE>'8G%&,4-*(4"5:'0.*27C':"(1D%+H%@E?A9G>$,!$&G,&'#".@$C-EH;?9@&7)./F>%;4#(&"4$)'%1)(B;1);/A5(319:@>%==>;4E'0".&6"D1E>@4C53=H?192C#--2$9E:A;*'(#;%*)3%*?+@2"%D79;5;*8$-H6?%#82@9+$@=H&C6@%$23DD1"-6:!6$""4:F(526AD33)3'*6)'>5>4260*6052E3(+#9F=8@B>-D".!13D*%C3)%6BGC!<"+D(%EGC1FH+$3&&#*<);$D49!=-E.$@F#!@">=#H>#/E:#%A@?%,*;*8183;?3"=7#!GA=;F.6.5&C8!23?>,',%?/2;$?)H>:C$FA0/:13&4!+8'H:C+:$$=1?!37E:%;E?5'>::GG+H%12"B52F;/(&5B19D4F##*<0DH;%0<,9/9DA07B9-58.@.7>@&13-/0+;8&4(4<&$-,->#4B37F%H73@$1-.;/>3F,+$:90();)A+-5A%ED?A";=0)7=/,>-
@r3845
CAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGNGNTGATAAATGCACTTCCGAG
+
G=,#>C=4C5=A7$@0<&!/4)/;-0%)3;%)A(B<--/18E'53*C&+B;?).+"@A++*2.7&<1)4!<2.!>#=((E44$1B0/$401AE/&"/&
@r3846
AGAACANCAAGCAGCATTGAGAANTTTGGAATNCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATNGATTGAATGTATGCAAATAAATGCATACNCCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGCGNAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTNGTTTGCCCAAAGCGNATTGCATAATCTTNCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCA
+
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
@r3847
NNTACACATANGATNCTGCGAACTTCAAAAAGCANCGGGAATAANACCATGANAAAAATGCTACTCGCTACTGCNCTGGNCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAA
+
##'++!!"+!!**+"()"##$)()('+(+!$($$"+&"&#+)##((&("(#()&'"%(&)#"$!*'+*#'%'+$'+)&'+*+&+&#%%("%)%(&#!#("(!&()($"*($!%$($&)**'*&$**)(!
@r3848
AAAATTAGTAGTATTGAACTTAACNGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTANTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTNCAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGCTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCNTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATNCCATCTAAGTAGTTGATTCATAGTGACTGCATNTGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACNATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCANTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTACGCAACTNGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTNTCGTGCGCGCATAAAATACCTCNGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTNCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCNTTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGT
+
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
@r3849
NTTGNGTTCNNNNNNNTNNTNGNNNNNGAANAGCGNNNNGAGNGAANCGTNATTGNGANNNGNTNAGNNCNATCANNGNNNNNACGNNACGNNANNTANTANNTNNNNNANATTNCNAATNNNNANGCANNNNGNCNTTNATTNT
+
!#"#!"#"#!"!#!""$!!"#$!!$#"!#$###"##$!#$"$#"###"$$#$#$"$$$"!"$!"!$##!$#"$$$"###$"#"$#$""$$$""#"!$#$$#"$!!!"#$#!"#$"#"$#"!"!!$!$$$#!"!$!"#"#"#$$#!
@r3850
GCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTNAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGG
+
6+%?=,8=?;G9;G=93C'-5/,$FG!%/D;01#%>=,G!&.E>8*,,;948$E(5"0?"+-E,+@"%EF/>D;"#C(6(G%H$45#""5D.',9&&0)=3(D=96!;#5$1A07A5(<C+7?6>@29"/F,DB3=6*+-().A843)!5/G>77E#.
@r3851
ACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGNCGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTTNCCGTGGCCTTCCAGCGGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAANCCACCGTGTCGGTCATTGGTATGACCACCACCGTGAACGGCGTTGCTGCAGGNAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCCGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCNGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATNTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTG
+
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
@r3852
CGGCTCACCGGAGATATTCACGCANGGGAAATATCTTTCCCCCTCCGGCGTGCATNCCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCNGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACNACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGNTGTTGGCCAGCATGATACGTCCCGGAAAAACANCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGC
+
&49>))8C<5"G8'8"H@;44?E@6.!+')&5.!%;H.A.(-2)B">C86C1(+7>*"0+66#"AB<%9.G7F=&*/6B+:57H"?0=D>AD4E>H$:+D;*)?0F'#HA&C&9><&1))*!.+C>9"60<2-2E;6AC.<$%2ECCF)52!:>F$!0F@)9,6)D>!80=+-5=G#53!@8"<:H7>):1;58!+):HF42&B/5?),,6G%?F?.$:>?0D9:29*4?C*-'&>!A?A+>%2G);--#-F-DG/?&.%.A!2<5#'2H@EH8;H.D72)++4GC=;G.=77<!;!#"<*6?#+4H<A4&"!)6117(HH!F$.D(04/5E":>AH897C/G0DA3:#3&(=&)=B-0)+:9!4+?8A6</#"@'@?E&!@5;5(:3+2D&,/91('7+1-9H!1&+6#9(!'(
@r3853
TCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTNCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGCCCGCATCCTCAAGCGCGACAGCTGAAGC
+
)(#+*(&%!"#*$&#+**+"&%*+)*!*)("'&%('!)*%"+'$"!'%)#)!'*#$"(&!$$%)&%)!(%*(%!*#%%'!$*"!!!+$*)%#)"&"+!()"!#+)&++!%!$%!$#**'%%)&()**')##%"'!)!"!%(')#&%$"%++
@r3854
TCCTTGTCGNTATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCNATATTGCAGTCGCGGCACGATGGAACTAAATTAGTAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACNAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATNTCGGAGATTATTTTCATAAAGCTTTTCTAATTTNACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTANGTAAATAACTGGCCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAANTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCNTTTAAAACGGTTCGACCTTCTNATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTAT
+
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
@r3855
CGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCCCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGT
+
=(A3-(A,2-AFHGG)CHA"1:C!HD7=GA(G;"'++*!?,*B:B57%3G=/+;:+FH*2C9+7)@-$)<"$6.!4!E(1?!<<7B?*2F7*D='$@*'&0#($>AH@GC+
@r3856
AGTACGGGTACCTGACGGCCAGCCANACNGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAAGGGTGGGGGCCGTCAGGCGCTTCAGGAA
+
D':2D%6188<(+6&/'A,@$&36@.:2:=E:'"5%)!+AH3?-C6.G9-%>6"*:>E2*7!3925-,.?,6%9(&*?!F+/6/1'+"-'C=!#><+;2E7A>=-;3*D*)#*4GE@/*BHC!.;#-<4!5<F:<'%7C91()!7DH#B!.*EG1-5$6D-!A!8!F3H3*5G6$46*C>G.9?C!B0:"$C%:G*?05?1+E.0?(4FA58G193)85;(.0E.C(!.@'"$460"'C1#='AD;*6=)83F!F<0$>&#9DD'#%./7(C0,>1C6
@r3857
GCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGTTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTNAGCGTCGGCGCAGAAGGGCTNCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGNCGTGTTCCTGACGGTGTNGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTNACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATNGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGC
+
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
@r3858
NTGGTTATGACGTCAATGTAGGCGGAGAGCTATTTACTGATTACTCCGATNACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGNCGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGTTGATATCCGTCGGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTNGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCTAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAA
+
"%5%G/=?9+"5'),,C91+5+%D1/C>&,DG6C?9!'8:C(=0%-9$$CG'''%4-&.:15F0F6$&1%0A:4:6,%5!98H$E!$39G70!=30A!B%/4#G2;!8?,(+=;5>H916*E5@>6>8/F*$?.?&7&GC4@5'$#''6#/!"C=*/.+,E+$";3:@-&54D*0=+--4.738+54"1;15#(&C<.-*8G=DA5.F3&H(2=<-"14&EH8/8)E6;;/5AB$$1GG:#%<0:6#@+-?$,<79-?*4.%=F3!%.;!2?7(B0@C#E62(4D+#F8:.8)6DHA,$6?.(>'5/+G<:.+.75H=;,B-.51/#?/$&F%3-HA">!8:G?G+BG)-CC7">6D8,"1>.?$?,2E00/-43"D3&46+8(29G@/='7,2(#8%6-13(-AG%B2EH,AGCDHHH!A8F)B()0-?"H>69110?*)?'B7*;4.=$7>!#.5<@B<D""BC"68;2!F8E.5C-H1%9%='BB9)'E<;9(+>*
@r3859
ATGCCNGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCANCAACATGCCGGAACAGTACGACGAAAAGGC
+
-,1*%%+#<E&8#$)$'9$G#$3'=)=$%F5.5&4#&31C.*H/-<@0F9>E70:A!*,'F).@5-FB.'"9,3F4!/(BH1G,4#/>3>.E@B2A20///??>C;5<*&+?*"-#9&>:E4A*>,,.:D022G>5E#B>$'%,"F@)@"@<.C/5=(A%D=-?+@E20,2)1$80"4G4:%98/<#<-*1#/)#H#/3@E:(8AF@E4B391/"(A:=;.3,6FG(F@&@C=HH7B>0F>0'C7:!#-"D3;E
@r3860
NAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATTTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGCTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGNACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGNTAACTCTTTCAGAAATTCATGGACAGTTCGCANGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTNATAGAAGAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAA
+
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
@r3861
AAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGNTTTCTCTCATCTNCTTCTNCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAAGTCAACAGAAGATGCGTTGTGCATACAGCCCCACGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGATAGTGATTGCGCGTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAANCTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGCCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCAC
+
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
@r3862
TNNATTANTCNNNGNGAATAACTTATNTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATNTGACAATAAAAGAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTACACAGCCAAGCTNGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACGAATGCCTATGGCTTCATTTGGANATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAAGGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAANATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCACGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCT
+
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
@r3863
CTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAANNAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCANTGCATGACGACTGGGGAT
+
B5CGD+/B52H,%72.''*(:=/"%';H7,8!/7B*1=,(?-)=A43F/@"+F9BHD0D#9'8H--:!$?H'06"7")<+5E%5<;F!>?HF7083E#15'=>.(@('@*'G@6:AF</$;1
@r3864
ACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCNTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGNCTCATCAAAAANAGNGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAG
+
7<#F<A(@5F3F"73'HBB;@6"/GC%#B+.$$,H!%B#$0*=67E)72.)41;*8!";;5D84#4.':;&A$G(8=@C%?'-'G&(@1.62!./9&156F)$!F8/3D<#3<1&<H&C,$79A!>;+7D8.@-%3;6-7%5778:D-A<>&7>1%9B;0#FBC,$C:7B.$4GB5>710F)1%H4F)#?'H>40;"(>8*E$$4
@r3865
GGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGG
+
<<@%3B&>7B.D'9"AE;$%G/+7!/$*A3(>:!8:#@.@;@8"/
@r3866
ATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATANCAGCTTCACGCTGGCGTGGTTGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCNAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGNGGTGAAAGGGCAGAGCACCACGCTGACCGTGGNCTTCNAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGACTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATNCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCANCGCATNGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCC
+
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
@r3867
TTCGTCTCGGACGTTTTTGCCGCNCTGGCAGAATTTTCTGCTGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGNCGGCTGATTGTNGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCTCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCCCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGNCGCNTCCTGAGCTGACGATGCAGCCTGTCGGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGANAAAATCATTCAGCGTCC
+
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
@r3868
AATGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCNTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGNACGAACCTGGTNTTTACGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAANACGCTATTCACGCAGTACAGCAAATCCCAGACCCANCCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACANGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGNGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCANTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATNGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATANTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGG
+
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
@r3869
TAAGGAGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGT
+
7H?,FE#=$$A4E%&4:6CH1&<5$(;'#?1<"9(%?;0=3$8:%?4GB>9%'A0$1>7?(@38;@=BB3@/!
@r3870
GCAGGATCAGCCACGGACTATGCCCGCCTGCAAGCTGNGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACNTTCCGTACCNGAAAAATNACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCCGAATCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCNTCTGATACTGTCATCAGCATT
+
5G!1/1*8(&DD7**+/?+@<4AC#2:,<*'F5)E)?;7A+*/F/A/01''<>,9;.=5;82=:?(-;6+0#.=-;>=DF?/BE?6#!??1806G,-6'B6-"D781;)%?'(F:0*:8..D3#'4E+B$8++$.'C<2!)84H1F-=-98<>+.=H"1A4+;7&9!)89>">6/0A(6D)12(,#?/&3B/4E$@.90<G!=.75'8"3DH;$31E0**40&%@1.)E'31=.G!>*-.BD5:?C!$>?=95*&F/$"E6H3-6#?#%.:-!*#/BE7B0,CF('E1@B=8523D@+GG!A./71569+""'8F+7962)*92
@r3871
AGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCNCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGATTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCC
+
2*3>D828=5A16E*,#,.7$".,GADA)9@A?0-3<>B((1>-E!04<=:C:"DB*EF<A=935'5#+64H"&G:74.D-C?.;137F"F-8,@>G35@'<#1@7&46A29)?8"*+B>GF6<G<)BC*:!8/E3H2,+6"+"C%7+@,3:A)8AH0"5/7))0:E38?B>F'B0!!DF:7<)=7<?:=H,#/#$$8A63$11:$F?AG"15"&H-,F-%*0)=6E*+)H$D-(/B5(:(-8H!F+B,9:,(/)4
@r3872
GATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGNGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGAAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGC
+
38470?48C1CDC%A&H&'#4.F"F<84D;@"C)=A'":3?.5FA<90(!.D?4!*B22.>A7$98@(=0??0$#$:(9+<,!!=-;@).A"0-:)4(/G:#!;E?,-8-;'E5#;6F$$)47,"B'#DD5<<(=-,%/042-,G$5%';9%:>*%7:5:8">+<..%"5)'43&/+*8;3HCH(?.8>3!"1HD-'7"7'G$5?=:'307=DC>.1,!8=>+1:'3:"8&7B'43&5/2.@A<C?9='">CAA$:.4$%D,(4.<5CC*?DC+8"="14!4$G8/0)04)A::(@3/1-*0";#-G2-$ED#:7@!&*=3;F..;"F1=>;4<A922=?*B><<8=>#
@r3873
CGCTCGCTGACGTTTGGCAGTNCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTTTGGTCACGGTTAGNCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTACTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACC
+
"G31A?9:/;5#$C6@6+1@39(/+./C-2-,"B77"G4%D6/E9&E>0F+4+<3GA,%4!$0)*B?>4*$(9G/<C.=H6.C5=>),C-&F"B/?)H&,B*?<;GB3.&3%*:$3-9>$)!;2H9/GAHF?B84;/A,''H5G@4G>62H<&C:%#1+9E%9;?)!!1&3#G6'CE1A;B2:=1C;B"-1);BGF=H."3HF?02CH0!EB"B:C:-D-"6=".-=-;=$E=8CBH=:>?2@49:F!H6*0CD*=55'A3-$,6&3@3/<(5;=#":=0)G;?(!-FCD/=0-G21*2923.4,;(E'0>H(H<<)&!9-+-AC9GA<1,B:>E;2?4%?&.-6+?,&?#+C@
@r3874
CAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACAGAATGTCTNAATATCCGAACGGATAATATTTATTGCTTCTCTTGACCGTAGG
+
+%#&)&*#))*"'"$'""((+&(%++)*)!"&!'%%&'*$(#"$(+&$+"!*$#+%)+!*(!%'*&))($$*&(+%*(*"(!&'&+&"#**#''*
@r3875
ACCACTTTCCTGACAGTGACAGNCTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAAT
+
%C99#C"*A23E)EH>?8%>97(=#,/+*&*C"C?8''H@FB(9.HCGF+>E"$+8A34'6"D1-CAA4AD.4:)@)('.0"A=B.%;(=H-,/,+B0A-B4*#,"67750$).B,,=33"&(H5685@@,*2)-;@:;<,6=G=H0!"+<;
@r3876
GCNGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGACGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACTATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACCCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTNTTACGTCTGGCTT
+
A?(0&G"E#>,&5=8H71'03H!&:1*(E:H!12*C3E':*DD1H%"C5"H*$@1%FCF4C:73'/2FA#83)$*1./5:%8B;2;:)$1+088BE&AACF'--$+H3H67&'=+EF&&;!93$:FG,C"BD-&-9A&D;H9)09"C;6&($8-#,)2:4'33$-%7G-,HF?F@26(>,,('*,H*##BCHB#<.EAEG/=?)=%$4%2DBE/B28.<@<0,E7-.*;39'-A)@!6:(-'FC=F4@='4=!'$/G%2#'$9$,G+@.-8*86E@4<*(H26:+'36;8D:$"1#57@<CE?F,*&,C>H.92G-"%;E8;01/,E:E*!$A&"('+.(0/;/D6"BE+>&)2%+!>92B&:5CB)4.FD.1!&.!8&B&:;)';06--?:/E,
@r3877
NCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCNTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGAC
+
"HC?13)@/7=%C;7/8&="99A5,B"C!#86,C'AGB'0,7*%6C$19-8.7&H,)A>-F0&8,;9-"8:3.E1390BD4;FB:>C2;8(=598+2;0#'":'=D'755<:#H(#.?F$,%B!<D,C*,@-C>B?10/>)=+2"15@HH;22#B-5H90'%0='2G#'8.!"><B:19F<@-D-)G.6??(A%#3H20%B8((FF44;AC9>*G1D>3-HA;?,3H*8!8C)$1<4&
@r3878
GCCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCNCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGCTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGCCTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTAC
+
!"9$-#F;'@=E*+7D-9C48G(',.>-A*%E"98A34$DB4C;E@$<:DAC)-EG/E<7/#;(H0)9H4A-G>><*2B3*$7C%06&@*>*641:22(E1"C%>HBGE:.,F)20-HE(G4,(6%)@G@:E2?GB/0,2.A#&7!&>AF2GD!<88/>B(99C+;H!(93%GG9+270D!.);4-5:?A9*BDG()8(.&.03.$)*3C0*63>74/02#<2!E57.%-15%/9!E2G8&E;G3"3<-*>$(-7'=AH0(4*-;$;7)@9(!1!8?)DF?!,00A<@E08(2)%3<:E.(-!$..8+#=;.=D-*.C5*?:$-:57B.7(FD9G,#!(+@>&=5E?:98F%#0+@$/"/F%9&G,!DCE9'7*@545!$660$0*3135+'*B/3A?4H9+-,!;(GHC:>9??@%$+@C)!76&9;68/+'H$?<+%2?#;$)&2/9,8(?/-.&G)H0D6&&AHE9E
@r3879
ATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGNTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCNAAGCCNTCCGGCACTGACTGGTCNCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCAGGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTAATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTNGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACNGAGGCCAGNTACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCG
+
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
@r3880
TNGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACTGCCATCTTCCGGACGACGTCCGGGAGACANTGCAGTCCCGGATGGACGCAACCCGCCANATGTTTGCGCAGAAGGTGTCGTCATATACC
+
)"+")#+"!'#&$""$(!)+($(+!)!#!+(*#()$'"%+!$%"#&$%$+()"#')'$(!$)$+(('"!'"#'%''%$%+#!!(&+(*&*')')%%'#"+$'$$"")*"!'(++&("&#"+!(&(&*%%)*+'$%#!)$)*+!
@r3881
TTTGCAGAAAGAACAANAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGA
+
8=3"5+:(D6;F1&(G=@/<F<CDH#C4(*'H5$359B>(2/,/6/,@3&<(A6-B6<4%B)(2@BA*.:H6CG&9@5,A->1-:?GC!G(<A>(4F++>B<(7H,4&%;,+(9@F#2&='4'/>C:G#@FA#0#FBG&C<G(7+D/@@B30GG+E&7'4.F";@C#7,'*B19A@92E@)4)
@r3882
CGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGANGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGT
+
4%1&0H51%30.*%5*B)?F@.((0=>!G15CH%A0*.>E!77,'1(A$BF"G/&$;)(E<C:@+#">H>%<<2.F9C;%*9E,@H,4!HH=5=0<90"!G,=F$:D=<4!=/FB:$!,-;!$03"BE72A,F5(78.!H2%<$@>F,'2/5)2<5A8,7<.618&7=C>FG.>9G6F-0G&$5/$*/D=8'>B$!D</)G;GG"H0">F>,(@2D?,7:7=:.<>0*?$6??AA!E.9#F"1)GB"EC8H=7C+;$0-($@5A9#!;%2*0)E2,)0?#=G739,:8517#1FG"(8@#)*'80&:G?2/7E:*63/?1$A>;E1!@BAH32*@=A9AG-C;D4:+,>H84,)5!B*C#H*<?11D=1!-4>=7)BC1%8-0/C0+,76!+?-9<<-/+.0)E41=@9B70#00'
@r3883
ACTCGCTGATTCGTAAACCGAAATCACGANTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGANTACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCANGCCTGGC
+
$0;:@$)(.@:+'0H%9,"9<%@=!+'>!=<71.(0?2<9?$,@,&1%4B96"-,@367HA+E/C!(!%EHACC4:2!--$;=4>1C6E?#!F<5H7/C+*!.&?;$!0%D<.'E91)9>264)C6G##%&%(A&'6#HF::$E?<H;-
@r3884
ATAGCTTCCTGTTTTGGTCTAAGCTGCGGGTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTNGAGATCGAATTTCNAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCNTATACNGCCAATACCCGTTNCATCGNGGCACTCTGGCGACACTCCGTAAAAACCA
+
@/?1BA"<21+5068%>$!1,H:=-/A=%=4!2B7<19&DC%<BD$EA-,8-&-3"H6"51)F<.1F@*==#42A3.&(AA-..EB&D)7+(4F80'HE4/E!1/F97*'*;63?4&+:3D<4C'07F,-B0H,%<E313B?CF0")<==D=4-@E(D"<H!3;+!$%&:)B''8@(G",!!F$.-=;-<EG7++@G?'=073.0B#?A-(</@F'5D/E>C0;BD5@A*D8(?==0#&G"1G!%!G%(C@#-D6@5'<?0*646)7181!,8%*BC-B#26@DH$E"E
@r3885
AACNCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCT
+
!(&!)(+)#''"*$(+&%#+$%+*!''%$''%&**($*+*&(**#$*"$'$))"((*'%&'()
@r3886
CAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGNTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATNCATTCTGACGAGTTTTNACTTGGCT
+
5A+(,3:H>#B8&%C&))F1"A<:9H)A,2"=F;D=+05CH!!B!6#?+@<06'C!6.9'!7+H%7/#@'#.80+60),#,AD/GE3/'AA3?F==D6?$B>(6D?/%?)"'DG;%!6F!AEG9,+H5(GG79C)9>9<*6A?H8/&6'&/*:19E5+!96<5E2<64$6>.A/AHE8)CDB%"!,>/H5?%C;AH/E2($/H65,<2.+!').E;6;4GB3-=4)DF8H90.A4?/H,,.B)9F6$C><D$88*7<?-'!("9FCE$CE842E?733#:1--8:)97(/E0)94;8H0)$4E#05<2/%%C:':)7$!>'8
@r3887
TGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGCGCGATAATGCCGTTGTANCCGGTCATCCCCGAGTACNGCTGCAGCGCCCGCGTCCGGCTCACCTGCGTGCCGGACACCGGCAGNACGGCCATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACNGCATCCGTCAGGCCGCTGATCCCAAGCTGGCTTGCAAGCGCACNAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTNGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCNCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGNTGCACGGCGCTCCATCGTTTCACGGACCTGCTNGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTNAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCNGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAACCGCGCTTTTGAAGGTAACGNCNCCACGCGGCNAACGATGGCCTCTTCCAGCCANCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAAT
+
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
@r3888
ACTTCAGGTAATTGGAATTGATTCANATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAANTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCACCGAGGTTTCTTCCTTCCTTGCAATCTCCAGATCTGCAGCATCCTGAN
+
=*>1F&<#$>?5%1>!F<"$2C5.;F+FEG>#$GB/$"BB9>H0G98/@#E@=!&F,9$$46,5FC?%'/)E9$)9CE<67F'C>5').;:$7?-F69=,1*4%'0"5<A=$9;$+("-)+G&)-AD?066">B,9#-*("-2+FD@-/+F5-;ED$'H6<C$$G@,@457'6$42+71>5/+82(%$*".#@7C<"#+)7?A;#/H3<&<H50-8%8(%%@00>!E4AB0-):4-&D5!25F57E>HE<C;27'7:2F-!H9*%27.B9)*E(?-A07B,>C$6)')(AB95;D5;1#/"7.(C&(4%G:@;>*F&)F"%F-*F(?:&221+,87$!(HDBE=D)/>F<&G6<E46(F>H$#H>7$,CB#6B#;&->8#<GB+46&9-)C!'?0H#9*4*'F9!)5&AH1A(>8,),)@9.2*85)8);!#!@#47!',527=<D<.:!5(B.E'?
@r3889
AACAACCTCCTGCCGTTGTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTANTCCTAATTAAATA
+
C(+&H<B5"EC=(BG-4&3D<H;=!"0<3421*/HDA!)E(#@8A%/*!*=%5(49F=071:C:#=:*9#6-5/'2/%59*HA9D%!D0(7+(!@0?!HD)3,6.'-#;%%
@r3890
ATATGACAATCAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCG
+
2>9A(6+%!$G!678B1B*45D">F5D99"9F(8"$>,#A&A:-66?!!:=3D1:AFD6:,5>;F6@9/G3.40/0
@r3891
NATGTTGTTAAAACAGTAACCCAGAAAACATTCGTAAATGGATTGCTCGGTTTTATNNCTTTAGGCATATATACTCCGCTGGAAGCGCGTGTGNATTGCTCACACTAATNGCATGAGTTGCCCATCGATAGGGGCAACTCTAGCTGCACTGCTCATTAATATACTTCTGGGTNCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTNTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACCCACTGACTGACAGACTGCTTTGATGTGCAACCGANGACGACCAGCGGCAACATCATAACGCAGAGCATCATTTTCCGCTTTNGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCNGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCG
+
'+4<:'@"/C)301<?=+A(989):/!1,69*G(;-8!2;6.<FAC+350'#.>%1E(G541.%"11/!5!1"6*'=3%B>#-05"*,:&D"=#$A.A6;)7'";?+0B+,,);F.#)38F0$2$<>D+@;"@/7F>".+:HBB/</9:('/:")0+.>0>3%34=(:+@!:58"'9<<0@+,?&(8/?!$DBF7F>@&0,(",/!-'9:@=>$89-,8;G43F#/38%H?.BCH%*18E7(6"1"7(0A8:=C=*/%)7G+)<?31>?=*A*3HE2&CF#-604925=@0&45)1*7.+2@0;HB=)E4900@+C&0&%4.35H/6&#+,!A9@5@"&)-'"GE.;(,0((-C<C#'20E1:0/,+8G0F*0?DE>*%5-658>?0+4/D#(/6F2!:%H+7*A.7-9))#DF#/428:CHB*<'*1CDGF&CBH'H>(&+6:'4H(2,B6E3#/(=?'6=;-'"3&7?7/E4=96;;$%04+7B/98"&
@r3892
TTTAGCTTTCTGCTTCCTTTTGGATAACCCACTTTNATTCATGTTNCATNGTGCACTGTTTATACCAACGAT
+
5)><>0BFE*0'05+-?*9-18(A!8)BB2&$/$.*4+3"9%;5$#C&'%<)%'>+"*'@5519-,:#'#+!
@r3893
ACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTNCGATCCG
+
=A1E"*%(>?99!EH2;/:8%H5;2D+7%B;,<G(#(?/EAH/1C/+&;DF1/$1/G&C(FF24CH4,>"D)63+.G<8H%-)3-)9@&(@*(E*329/0*16.?2,$C08;=%58,B'*=7HB<*G/<?B-</:#6FFA/1#>G+':!09B!2D6.=)?$*/FA'H*;E97*2FF?#B?$G6!)1-/4AAHE'$%9F8?+.1@%;H(B=:='H16&)C9>).H"-9&<D
@r3894
CANCGGAGCCACCATCGGTTCCAGTAAGNTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCANTCACCNCACCGATAATATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATNACTCANAACAANAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAAGGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTC
+
&$(+#)'*'**)*''%*!'##%##''**%+$!'!$+('')&"(!)!"("("$)#)!)$!"+#)&!$#&$)%%&#))*'#"()'(((!!+!&'""'+!$*)#!'+&(*%"&!$$$)%#"*!"#"#'&!#&*()"!"*+*&''+"(*&+)!%$$$*+#'*"$%%&!!%'*"!&#('$*%%+''(%+%*'#"!!#)$!%*)$+&!''+')$'*'((**!!+*'#)'(!"+*+*&)%)+*!(#"+*##(%#)(($")#*!*$$####)'%%#$&#!%*%&*($#!%&#()(!!*"&&+)""!!)!+*!*$$!"%$#'#$+'('+&!(#$()!!*+$!$*!+++)%"(())*%&'*!$''&%#!$"$!"!$""))"))*')"*%$*)!$)"$$!&$())+*%*&(+$+"')"'!#*""+**$!##&)')+"#&&+!+)+$)!&"'"&"!%"#(*#%%$%%#$()!*%''"*'&(&*
@r3895
AGNAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCATACC
+
#(&#)#++())#"!'!)+($%'*+%#*!&*&'$'*'+#$!$+$!*!)'#((*)"+#$#)+(""%#&*'+(*#))'##$)$"'+)#)%+#+&')"$(
@r3896
ACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCNCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGCTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATNATGTTCTGTTAAAANATCTCCGGCCTCCTCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAANAGCTCCCCTTCAATATCTGTTNCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTC
+
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
@r3897
GCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCACTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAANACTGGGNGACGACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGGTGACCCTGAT
+
D;',G4H"/E65,C>+5<$*&&#/@%69@5(B&7?8/=+C7*54!:066HCG*B+2#3&,D6'+4G60%#?4?E='*81#4D.,,.4<C2<D@+?AF*';36HE*0.7!<D>&2A526!G1?0.%?B8'(65@+1BF=6$BDD#765$/(96BHG(?8:9#1=6,)'/7!4"807"<(/&"7%6-8#-1''1>!<)@-=
@r3898
CTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACT
+
H/$<B2@2DD71EF/79.;A;/.*%6"(>90-5/3D<=%1A91!-=7,'0/+<?-@*=$7)B/,$@*0.+/)#B(9-6'F&?(73:D,4-/!:2#!56DC=E2$#3F**3A83)!*@DH(4776;A/%+;.*&C2C%'!<E90%C)'2"*G4F@;E(B0699'78670"E3H;415E8@-7#'>G(%5E,2@4*BA@5=,88+3%5F)9C?8!3+@(G?4=5-B"BG46G29H/E.<)!;7!E0.."&/6!(&/>',5G6!.%/+#&AE><G7B4&#=#(F@3"A-,0(A)=27<,91H!.H4;C?!:GGC-F='2E@0%EAF-5*A02)E#,%/:!/98D*?-D!$,5E7+6'=90=+:>2)(26.*&(+F-G*(!!+=#H(<?@-++G?<H$8EA/2,@/G@H8.!;9-$=F,-281=8(00*.!.H2.640:#G"&,<2.,>%93
@r3899
AACTACACGGCTCACCTGTGGGATATCCGGTNGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTNACCAACATCGAAGTTACGAACAAGAAA
+
)F+2B074#32&5F8%".+,((*40;32*G5(HH<+,8%B=/*C)-"1E;6G.G@4,6"$3A98=%,+*<4C/*.4AA%25G+&+*=$3)'(6
@r3900
AAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAAGCCTGTACATGCCGGATTTACCGCAAGGACCGNAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGTCGACTTATTTCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTNCTGAAACAGAAAGCCGCAGAGCAGAAGGTCGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAG
+
/#8+122E.9@@D@CE)7-%*F.@G0AH'(2#=#@@;/?(D+7B24<''8B)$4)A1&*G;?D"0A.@)&.?:&5"7!@&+%B',6#*,E?!1'5H0?6<%*+EA-9.98;F"7/*(>G75&#75#,@<-BH>%%66B0!4'4B23:-E5(9@7=/1%53.01G"(0"+$')@/=B69-059)F9&/8%<E"1*H1/E:3/18C?"2&05GG(+HF0/&@H1=$&?)34206G.B43$9"(?;'C(=@7=*::5F;%D0/2>:G')%+D)%>H:92;$!*12#8$F8?A86'*F%3-0E(&<==>:%/@B=,//,23)&FC%C98++06=;2A-=@3/3?21E/?&5==(C>C8=C8+GA<=C<&*6G#)*F$37E$7@#@13/BFC,(4B',$D=5D%E1244907$@)G-&6;>+)$,>71;C?)&=F%#A"'GH-+B-(<<1'E%C'1"*BEG7,!%7+!7:!@$?613%.*57B'(>-0.F"=<A!<1+#FA<5'$'=8(8*'."4=24+&0-A9.1*2/&A299('-B@#1EF5/<")$3-491-=?;0;$#3!,C8C#/-(E(7(&3/;2(8<3C3%1%(@G*32%?;8D-A&;'):"D15<B/0("0%BF=:@E"&A33/;#/)>-'96/BB$@@)@B32"+6)>#-#17?*51.3=6+;2,<<>4!2;=:A(#<(<-99%<DE84.G-+4*
@r3901
NGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTC
+
'&>"&!A(=5'H/*4$1.B*")FFB9D24##4,8B%"A6((D2CB<8".%<$8C*,!#&/=<&/.):#F5E2?
@r3902
ATAGAAAAAGANAACTCCGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCNCATTTCTAAATATGANGAGTTAAGACGTAATGAACCACAGATTCAAATGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTNACTATCACAAGATTAGTAGATGTCGTTGGCGANAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTG
+
,C6$7B/89=5>F?(G910>E<47>)-"$"F0?9A;0B3-,4382F/#894@=,#.>D>*<2:9.?'*;;".))!=A*4B?,%?)=84<7$&6,,=)&;D+,.+#%>%-A!?,4;+=%CF6>*$8+7C8>1A"=9#40D9A?@&7BE:GH:,!F)A",<D/1;>8**'693E$(#14G6%@<C+BA3DF7>52H(@3E9)+?.3-1/0:-)>6?!!4%/$'#,50)B</-3&.,!6(>F>C8#=C1EE*&E,2B:>A.42H7G@GC6!+8!)#3G="'</:F517C0EB7
@r3903
GCTGTGGCTGATTTCGATNACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACA
+
+$)#!'&#!)"!%)#*$""$('#('"'*"'#)&+!*+'*')+%'#*!(!"&!##('"!!'+'&#*%#**
@r3904
GTATGTCGATAAGGCGTNTCCATCCGTCACGTAATTTACGGGTGATTCGATCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTANTGGTATGCGGTAAGACCGCGCTCAGGCGGCCTTGATAGTCATATCATCTGAATC
+
6&=B/A7,ED.1'0%280"/6+64';&B87/;7/G94?H&#&)G0<7H$*"C-0.!'G2"?&(2*G-E;H2188-3$9?#"F33&,H#,.*F&3(&'?<%F+B@)"(6,@"/2>D&F&!07.2@%3D:45'>H0D0G3?*A46B4&%E0A,A2@1@$!0=%#DC1E<::&H@+3*@'.:3?85@03,F/>2AH;$8%"B)=>6#$4H'-'*F$B
@r3905
CCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCNGGAANCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGANTGCAAGGCGATCAAGGCACAGTACCAACAGANACTCAAAGACCTGCGAAATAGCAGAAGTGAGG
+
D@7@><,0<D;+D4)6B#CA5>9<F5#B<#9&/F#E(==6H";4B=--F+800E(8H08!F)9,=:B;@G:0&7D:!3!&3@EG=5D/&9-6&6";0?878<(1-:>525AG6;2D=?,HE?.HE"!$&(()(?@H)D&G.CB./$E/G2,'F+"C7?;G++F4"3?%D$H.'A#".'%+(10/;*+(>@"DH>FA.G#>&38.A#8D!""#H/A"E'//?7,7!+;@!'GFAB#$4-*HA!!)?C164=@F>C
@r3906
GCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTNCAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGT
+
A9D)/D2+1A7F%D<2@3H*0.F=F>2$5+$>:)4?8B28(A;7"&*++-9;%G(C5/(6!>$=B'D0=D#+5'.6$4!6B2C:<<>!5"1=25'!*='G>%#-,"%".>F;B"?0A>B-*+F6@"$?=E-3,!ADE94F)CB5.($)74:-GD19DG7F;2BB$:B!;60;?.2G574,@>#457",H=5EF<4
@r3907
NCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAAAGTCGCTGGACGGTATCGCGTAAATGTATTCAGAAAATGATCATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTC
+
)A3;<FC:'!8D'@@1,,4&<4*%B@%?!C6E9')EA7H!<=5.F1'*765H(5,=4).G=9$!,%=FC:"!D"@;3=7G#,"&E#&2-B0@3@3B9>E,G%H:G77)G*>$/89D<:&<%/%*":#,(F0+A-GA-H/>&%!%,H)$'
@r3908
AGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCNCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCGGNANCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTNCCAGCAGCTCGCCCGTGAAGA
+
6(<3=.%"5%<,B$;#!B(1"DG;DG;A(H%?!@'>8!-AAE297*F83@6$D"/*1/A.*G+*=4:'=B,6<*BC19<34#*D41'-*ED2-"$HC-HD*<H?+36!==$&A@B(>:E?"$;-;D;H?H7+H1A;$0(3(73"9G=C40#?H3<'532G@3,'0C&#"CC50:9
@r3909
GCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCANGAGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCATCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTNCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAANCCCGCGCATAGGCGGGTTCAANCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGC
+
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
@r3910
TGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTT
+
CB(8(>!C'*(!3A(68D963)1#)0DF#,E-892)=H';37?,.@94-#*#:6E1F:HB%1B-)?C3E"6DA0%F$877=)/3FH62%F0:!FF<F%D.9!+0<"@@;(/(H!>?(&8
@r3911
GATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCAT
+
36(/3-0#:,:#A**H;?E@:1'$?<C*7HH-3%0?;?6;3'4"C'56,7*,&H56%&;"-2H+7
@r3912
GTTTGAGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGNTAGCTNAAAACTGTACCATAAACGGTACGCTGAGGNCTGAAAANATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGNCAACGTATTCGATGTG
+
);$5E%;D9.)1'?4F/<5%F@(;G/+=2&E>'$/1H;6B81D0%+?CHEG.-37(>(9600*$6,1*@0H)=D1%E#,.6>4"9EBH.+?:2B6"+E#&/?B2*>;()4540@5796,&?&4.H<17,*-CC2#*E"2=;?)<#G8%*;8-(-284>C;H,2D6&8E.'+)F*467:.<3.C6E414<..&A1D>EG@"6>,:2@;>?:9HF.B:01"A80B9;3>.=E8/5HB;?H$!5C(G2(E(B?#0=='905F%'C10%F<)8+9',G>0"0*&DGH0@1)-,EC?&><A7($E8&!?=1(E+48HFC1=C?'G/'C..%%E?,9":,&+A;3,>70B4$=%>C$#A!)H5'4ADD:0F;C;AC>#A3.6+A-*H!+1..<2EA62B+@260#9F5>-H03#%?1C*>@85*F7/1!9(
@r3913
GGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCAC
+
A(.=4?!@+4:D&<$1C,C9"2*/B59'>*"G0@+BCHE39&-2&>C?#>);1/
@r3914
CCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTANAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGNAGGGATGTTCTCACCAGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCANCAACAGGCTCCAACTTNCCTGACGGAATGTTAA
+
==,BB7HA2A=431G4@>'80-:A*,-4<<H-#3$A99+83")1<"0/G55+2"E)*#HG3F+;9*$%H@)$:"'$=B&1.63$#3-<+<,'-"6'<'%)8%<B)CD+9&'C9/9A,G!(0H:C8-?HH%"%>D&=%/;$*-59F#9<B)D9>@*BB3E+')E7F52((($*5/H/@H>DHF8G<5G?6%+$':%++4>FB?7:,G1B,#8(C<=H<$4,F%E66DE46H>*$4+&>?&1)&>)1=$D!',-)7/02:#@62,9#E-&$2$9.5/'$GC<E@!+G.()2%?+@8#2H+4%%C%)@E>)#FE:?1A;>5$!->@@>@@D6@%EBAC)07D+#A#*6*=;%+B(18A>*;96=5.($'H*'3"-F23*0E)#@8;H$GHA.F;5!@B1(2="B$*(>6G.3=CGH;48:C@-=='.0*@"2>F*0!;%6B4FGD"$*>;-34G2$E8%"=)2E->(A((2=.63*4A@("69:>E(4*%<2-;BE)$+>">(&2:>)<><EC328=E(2%:EF5*D?>-%-%?@:5CF#$"D,F<?2#%#A(;C:6"7,D7+G?3@2%1@>B:E>C>%*7(B#$B4"<B2:B&A3,-9F
@r3915
CTTATAGCGAAATGCTTNATAAATGCTCGGGAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGNCAAANGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCC
+
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
@r3916
ACAAGACACCGGATCTGCACNACATTGANAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCNTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATNATCTGACACTACAGACTNTGGCATCGCTGTGAAGACGACGGGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTNAACCCATTGACATCCAACCCCNTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCNTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCNTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCTATTCATGGAAAAGGTCTNCGTCAAATCCCNAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATNGGATCGCCACACTCACAACAATGAGTGGCAGATATA
+
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
@r3917
TTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACANCCCGCAGCTTGATTACGGGCAAATCCCNCCGGTTAACNTTGATTCTGGCCTGCGGATTTATGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTANTAATTGATCTGCATCAACTTAACGTAAAAACAACTTC
+
:A+!@)B-'##+"E,:>)#:?$F<;:,<DG!?")>>!>1)6C1<#+"(@%B!H:H32%6>F/:8!C;5?6:H>(3<@2!(>E711AH$-.#;'<3+'2=A--<G/'*G=A9E/%/GA2+D9H3+%2:#,;#@/$B8(!0%A%)=<&+$:)?9>G.+$HH=;/B0(3.:-,*&)2-:9'!>,F!!@*&+#-'@%#7-%,<>*G,8//9!<B?8$/#$6E91-&7,:&/)G1*#<BD/1:&A6<$F30?DH5H%8H"/?+A6)E*<.<EG&+,(3$B)B!
@r3918
CACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTNCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTNGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGNCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCNGGGCCGTGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTNGGTGTGTCNCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGC
+
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
@r3919
GGGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTNTCTGTGGAGGAGTCCATGANGAAAGATGAACTGATTGCCNGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTNAAAGAGGA
+
@,D2%:,;3E372*EE3-E:.H.EGFB<57"3*6E;?(?>.!(5'A%",:60;D7H<1"&*46H,9@A?/08*3A><76$D>?G@#G4?'3663</9+7F/-*/",:%/-C:!,E)-9A0%1@>)<#2*&?(7-('32,03D:&*C*:!4%@"@@)$B-=:5BFDH1/D23:(3H2)5"E#6(2"(E-9B?$@79/9"%0<E&(,B)E-!<5$-45:B4(=7>(%A;F%-7:$$1@#=
@r3920
AACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTCAAGGACGCTTTCATTTTCAATGTCGGCNAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTGTCAT
+
70($*AHG10:85;;53%4E#!;&!%C>!A,&>"##3-C/93G,->4#.6>'<DE)0H#)/FE"*/2(%-:'94*52'8E+1A)#'@C*%>8H$6">68ACHB@&.$=H9E.E,+8-B06E7@E.+'2G#
@r3921
NATCNACCTGACAGAGGTCNGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGNGCCGGTCACCTGGCAGGGGCNACNGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAA
+
#%((#*+)$%+%"&%"!(%"#"%**)%#""!(##))')+"!#&$)"%%('!')&)**+'+'%$'#"&%(&"*+((+##'(&'(+*+!'*$!%+*+)(+"$($(")%&'#$"$*&'+*$#&!'&+!*$)()+$'%!!%#'
@r3922
NGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGAGAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGANCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCACAATTGAGCAGANCATAGACGGCAAACATTATGTCGNGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCNTTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCNGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGNACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATNTGACGATAGCTGAAA
+
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
@r3923
GCGACAAGGTTACGNATCAGGAGCGCCNGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTNATGCGAAAAGCCGGGGGCTGACTGACCNGCAGGAAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCNGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCNACGCNGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCNGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATNCTGCTTAAGCAGGCANTGGTGGGGATTGTCGGGAGNATCGGCAGCGCNATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGANTTACGGGAACCGGGGGCAAATATGAGCCAGCGGGGATTGTTNACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACC
+
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
@r3924
NNAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGA
+
)!+&(!!*''*(+&)'")&$$*!"(!"+"('(+($%*+$'*+#(%"*#%!%"!$%#)+&%&!))"(&%*&$#"#&('$+$+$'%)#('#%"&&
@r3925
AAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGANAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGAGCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCACGGGCA
+
HD(C53=C2D<C=B773;?1C@D*'2*A$A#&=80"+E(82!-""<;4'DF?'+5B34*=4'D12"95+B:BDF<)C7(:-/1;H&;".#F@0)?;)476(5F+7#;9@91/$7:+HF#='A#350ADD7?5!C@)H"0"=D,>?5A9.0>8
@r3926
GCTTCATACGNGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGC
+
"8H/997?@7G>C:;"9%,GD6B-*(!408AH$D>?/+''A)8!D6%-5#(8:=B*;(A0H43!06.DF4!&8%!F%E3+75%53"8F>"15*!E28F26ECE@2'&4.H1'&G)99=-6"G23=-D'/$8,7D;$<61C;A*6/2+
@r3927
TATTGCTANCAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTNTTTCGTAAAAGTTATAAGGAAATATAGTCCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTAT
+
)?+0!7;"-<0#%8!!AF)<HF-790!"26,G'.F+)?EA$=?5A8%6->H')4<.)6-9<*2!G,9CC*<'7#FE@..D97/'(C3$7$##9;0G,%@3:169C;&C4A(-*!@<39+C4/'#=>0A<G/*7=;>3E94A3&317)1)6640FF/>%G@)=3>-F;%+&A8;:EAD8"?&F&'=F#7/B:=E9%)"C=
@r3928
ACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCNGTGCTTGATAACAGGAGTCTTCCCAGGATGGCNAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGCTGCTTTCCAGTTAGCAATACGCTNACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTANTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACNANTTCATGGAACAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGNGCAGCAACCAACAAGAAAACACTGGCAGNTTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACANGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGNAGAGCTGGAAGTGCAGACCGGCATGGCACAGCGACGCAGGGGACCTGCNGGA
+
+'%"'$&()$"'+#*"$&$(%+")"'%!+!&("&&!!('!'%+$##)"$*#%+$%"&"($'%+&&#($#+"!&##%"%+$)+'!$*#&+*#)$"&+("')#'##!'#')!'%$!'+)('+*)(!%$)#$*+#!+#&#"!%)"(!!&#)%**+"&)$+!&')"'+'#+#)'"))"*"*#+*#%"##%%+#)!%%*##(&%')$"&)#)&')*&$!"!%$+!(!%#"&%'&(+''&("#)!&!()"+++)#$%%*#(""('#'&*!(&)'*#+"()+)!$&##+&**'*++*(%"#$$"'+&#%)*+%(#(")("!&!)*!+(''&$%%%#&%%)!*'"&!&($)'('*""(+#+))'&!#))&*%")*(&$!"!##!!(+#$)(+%!))#)$%"$$*(#"#%#))+'"()')*$+(+#"%%+%+'%#))+#(+&#*&#$+&#!+!%(%*%%$!$("$''*)$*#')!&$"")""')#''$+($!"'#""$'#'%((+!*#)#%'$'*&'%+*%&!&'&()!)()&""'$*'#%'(%!"$**#'%)$&+!"%$!)"'%!&&("$%##)"&*!#"$%%+$+!*"(#)&!#'$#!&"(('"*&+*%*&$%#$$(!!(+%+$&''%%$%$')(*'$'&+%(")''*(+*$)()(*%!'&&&""'!$&$*%+*!)*'+)))$&#&'+$%$&%!%!#)&)'!)"*+&%%*'*&$###!&)&*)$"*!'%#)#(%("$#)#*!)##$!#)*&(*('#$!"+'+#**((!#)!%!*)#!$$!(&(#"#+#!%+)+"'!'"()&$$%#(""&&*('%+$&+"'&&%%#'"&'"($'(()))"%#%)'!#)+$&"!)*"'+'*!%"("(*!)'++'!#""('"))##)##!#""!$$(#)+!&&))('*'%($!#(#""$!%*+'%'(&*%%%'%))&)"((#&#"&+&$##&#++!(&+)(+%()#"&$)+(!($$$!$(')&%$)(!*$%&)+*#!&+)*((()$%*"&($%)**)'$!%&"(*"*!$()'
@r3929
GGGNNNTNNGNNNANNNNNCTNCTAATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCAT
+
%#&#!!*&"&"##'##&%#)(!*$)*'+)&*&&+*()*#%#$!*&+"*"%)!)(+("#%%("#$#!'(&'+%)$%($#)''*
@r3930
NNATCCGNCGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTGGAGTTTTGGTTTGCTGGCTGTCACGC
+
$!+(&+''&&(!$$)+*%("!&)%(%("$'(&()'%*#'&($#&&(+++*#"%'+$$%#!+(()&#&!''&#$+*'(&(#"+%*(#*(+)'&'%##"&*&)"#&!*%)&'!((''%'!!*%+
@r3931
ACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAA
+
-5>!3D9?-1B/:('91#6=;'A,=..*>9671>")?'203*&&/-E+1E88&@6-$"D'G<9(=>$4379!!$HGD8*>5.BG@;>.1C40:.G!)F98?:F$+*'(B52@=B,''2+56!#9&6!@C
@r3932
TTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAANAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTCTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTANATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAANTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGNCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCNCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCNTGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTANCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCCGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATANTGGTCAGATAGGATTAGTAGGTCGAACNGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAG
+
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
@r3933
TGGGGCAATNTNTCAGNNTGNNANNGNNNNCNNNAGACGTNCCNANNNGTGNNNNTTNNNNGNNANTAANNNCCNTNANNAGNNNCGANANGNCNGG
+
!$!#$#$!$""!"$$##!!$#!#$!$!!!"##"$"$$""!#"#!!$##"$"!$!!$$"$!!"!!"###"$!"""#$$!#$"#$!!!""$$!""###$
@r3934
NNGGTTGAAACCATTGCTCACCACCAGGNTGATANTGATTCAGAGGTATAAAACGAATGAGTACTGCA
+
($#+&+*%$%''((*$&*)"%("%!#)'%$*##$&&$'$(''!++(#$&+'*&#+"!#)+#(*!)"&$
@r3935
GCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGAGATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACNCCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTNTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCC
+
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
@r3936
GCTTTTGCNTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTNACGTAATTTACGGATGANTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCNTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAG
+
31H7"G.B&.*C6C">8<H$DF(B,19E)"C1"F@2:7%/E+0)>7?A/D/%F>4,G;B3$3G'*<?'G62,3"25G>50G>)?0+"<641F'$?4-D7(>9=#(4/7$10@1*;H=.3C@"$-*('9="2B&?/%1@@&850505C+'8+G3%D75?GB?:$D6/H+(,&2D16//)-:@2(*)CH"'F=(C<(,.A="F<*)/G#3*4G7.!+(<3&.'1:(/!:#B/03<A'DDF@*-34D>(;&5EA<2+*>H)/6;&DG0-.'"@5$?&%,1B'.4$@#/?E()4"3??'55)E<A%8G-F?)%A695@*586-(=&%1="?G$99/@+6D68>*>14)A#2.,@@&)CD06#;<@=<0.;E%-;A78627"2"73C,,)@G8%=B.01++=.&2G3:23(!"34D(#?9%H*<';+%G6&H31"4H
@r3937
GTACTGACGGATTCATCGTNGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTANAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTAC
+
@&C27B73+HH;,?&61?/D=B#C#%<9G%?*B:7B%HD19HE0%-:72/)&56FF5A;%D''=7G4-+=,;3F"@<,=9'6DGA."=G/A5807:G(H/>76HB5E4*$H$3%32:?CE4/B*!7=22&+$<$&-A/+%H?'))8:9E'CA+@D#1
@r3938
CTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACNTCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCANGTGAGTATCTGCATATGATGTCTGACGC
+
6D.)@60=='=82@*!2#':..B8;3++"<A)D4!!B=H=9-E=1"7&@<2:&B).0?#0E*,>.E!->8=3;*=0!->$FE?-$8"HC=,H7@0,3*9((-9-E97//!4=H".*D4B2=CHEA7(#0>)DH$
@r3939
NNCNTCCGGGAGGCGGAAGAAACAAAANAAAGCCTGATGGAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAAC
+
#!$"%)&$+%))%!%&$)(*'!*$*"'#'*$""+"$'"(")%)*(%!%#'$*"*!""#)"#)+"#"&%&((()'('!+$!&!#%()%+"&$&**(#%(%)!&')"#(*)!
@r3940
AATGGCTCTCCANTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAA
+
G*4B=F#(>*5AB#'G$A=!+$/&61$>4,(H-;%?956?+"41C=G;/3DGA<(.$
@r3941
TCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATNTATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCAGTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCACTGCAAAGCTTTGTGTGCCACCCACT
+
*$)+!+!'*(!+&+'%('"#*$&!%+$!)"+'"(+%*%#(&+#$#*$!*"*'(%'('*+!%**(#!%%!"+%!*%+"!))%'!(%*(*"()&('$%$%+&&(+'")!$+%*)$)&!&("+)(!!$(#%"+*+***'*!$"+((+&"'#+")"&+#$(*'!#)#&!#"!*#"(#*+&++!)!%!"+%')""'&%#!")$$*(&+&'##%*(%$""(#(%)(("#%#*$$+))##"%'+%&&)##&*&)!#'!)")"&*(!*!!)*#)$$*%&*+'!(''*+'$%"'$'"'&*&%!+)()"+))**%%&("+*+&&"#*"*"#+!$(#&**+%+!%+&$'%''&('"(((%$'%)!*%$)!$'()("!$!)+&#!'"*%!$&+&(#+''(#)%)&'+)')*'(#&&(&!+'#"+&+)*#%(!(++))(#$%%!&$!!+(!((%)$))%"''###)"(*%#+$)#%#$$&%&+!!)%##!!!'+'!&(*'$')##'$!)')$##'(+$"%+#*'&*#)!(&)'*+&&
@r3942
TACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGGGAGTTCAGNNAAAATA
+
BD,D&B4;(&50+6/:8;)9G)HEC(?($?&=00?</-("$+(;:)=C*,-8'8?'F&'?#<&8:/?3G6<44#4%G681@8*C()A2<:+<F:$,,$&822&.#=+BCH@3:C*H1D)#&"2!+<E2F=?HH2$054!+.;6</)G"FA"(E:05-)?#/(:(7-E:F:?&
@r3943
GTNACGAGGTGGGTTGGGTAAGCTTTGGGATTAGCATCGTCACAGCGCGNTATGCTGCGCTTGCTNGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCGATCTCTGCATCTTGCCCNCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGTGCANGTTGCGAGCACTTGCNGTACCTTTGCCNTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGNCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTNCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTNTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCACATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTANCTTTGCTCACCGGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATTAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCACCCGTGCAGATCGCCAACTACCCAAATATTTCGGATT
+
'&&(%!*"+'*%)"!!&%$%(('%*(*"#$#"$(+$'"!$$&((%()(+(+(!&#'$"(!'%(#&"*$'!%"('%)*''!&*"*%*'&'!!+&%**$+)$'!#$**!%!%)"$"$+**&&"(%'(()'$"+%'!''#!%*#"'"#$+%(+$()&""(*'&&+&+%"'""*&(!##*"&%)*&""*%+"$'$)"''!$+)+'!'('$"*!"&"%*#*%'+'!))&%&!'+))))!&#(&$&)%$%+#%+&''+))"#"**%%&(&"'"#*"'#+&*&+*&'**$*'!%%%%")))#%+(((*&%(&%*"'$!&"#'&"!**$"$&!&*("!*#)$)#&"+$%&%&%'($(#')+!!%%&+**(!"&!(($%*+()!#+'+#*!#**%&''%#)'!%'&+(%)"%+*))*!!()++(()"&*!"+&"+$%&$$$+"$##$#))*+*(*+$!%&&'*##*#"*!&&&!)'(&&(+#$+#&!*"')$"&+$%!")%#&"(%+"%)"$$#"("%&###'!)!%"$$()'!%(++"($!*!*&%%##&***&(!*!&%((&&(%"%!#++%$*%+#)***#+'!%+$#(&(+%$%!")#(#++&$+'$'''"$*+(#'%()&#%!+)*)$'%$"*$+(*'$'!!$''%#%!)%*&)!!(!''$%#%&$&#"*$&'+!+*)(%&**"(+%&""#"$"!**)!")&&""(%)&(+&#+#*(##%"!(+"$&!'#)$+"(#*#!"!(*%""!*"&$*$%+!)#*#)#%')"'%)'#)!$+$+*##"'("&"*%)%&)"()#+(#+*)")#!&"$"'#'!''&&#&!*$#(++$'*#"'$#+$%$)'#(&($%)*'#$'((#&$(#(*#$!!)"*%(&+*$(%'"(*((%!+)!#)!))$%&(%!)#)!(&+#!'+&''$(#*#!+"$!'"#$)$#*%(*$(+%'%%!(+!$$(#(+)!%!"#%$(%$*#*!(##+%#(%!"++&##"%'!)#"(%()&(!($(!+(*(!"'+#'++&)''%)##''!$))(''##&++#(+%$%%'&)*&'%$&$#("!*%%&#!%*$%#&'+(+%*+"#)%#+#$%!+!!)$+!+%%$'%(#*(%*$($"'%!*$#)+!*&!&+"*$)%))#%"$#!!)!'$('!!'+'()$'!'"!!&&'%!%"%#(
@r3944
AACCATTCTAAAAAATTATAATGGTCAGATAGGATTANAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTANTAAATGCTCGGANGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAGGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCNCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAA
+
&'B5GD=+%D<H-)?C7&2@@"'/9H@,37"*2#4@GA00'(*27)=3G2C/5&AE,1A9.5F7'+?E*F;@5&.>8<1;&E651&-25F"83F$H%1E$E!%772C(2+*+'7HC5B+/*''#C$2)2H4%1C3#>*%295.?0!.#6%+5G3E4$:",1?CED9;2+>)..F*E="?<(DE)9E2(,?:=/CG?7HH-,G6$.=9*#;=,B3#HA43H;05AB:C9C4:A1'9''D06;6"@!FBC%!>%BB/!##F+35)C8H,9@.(H9A)E(&AD.7'5<E,5;G@9B;?>14$*?).6"4*"20H9)411%(=C:=<<%B?=@!GG=)>@;%7G+FF8HC%/,?@F4ECF,373H=)*1%?((DH)3.;F);1/@22A@.*"56B"H'D7'-?<9+-*(&=D>.26'&DEC!H&%D3B/,&!?::=>!"$>BH*8GA#6@G2<
@r3945
TATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGANGAGGTGCGGCAGCTGCGTCG
+
''+*!")!"*$"+(#'(#%+)(!#'*&"$+$#(*#"*"&!)+"($&"(($&"&$!+'"")&&)(!')%!&)$!"##"+$*(!+)(($)*#+%#*$&)!(&%&"''%+)+##++#&)!+&$"$"+%)*#&()'&&*+#!(!!#
@r3946
AAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACAC
+
73<@#F0?D)-4,'B+A46&-;$,6=79%H8,>-#0.24*2,'G)<C,)8)$(A9<,*F#CE3&*++%++=B*H0H89@C7;2??DH+0.(+'0/3-6.>:A>316C31E%+"H%9GE*H?%B!B,3"!0;)5<&2
@r3947
ACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGANTACCTTGGGGCCGGTGAGANTTCGGCCTTT
+
$;6>:@C.53F%E-,(&5%;):%B/+;D.$D,0D!:->0!*<$$H=;72E<B.A$)7<14#2375B).H-CA9(B33A#EE#1,
@r3948
TTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTCTGCAGACCTC
+
/"!0C5)$&1.;$3:,E>GA-?5;0DAH'@;!#-63*.1EG>2G'F3;))E8=)F)8D$,0&3>9A4&H9A2)G129(/%F?C@B@98-,(06:;&.2&C&#4=+!;&FEC&&E4G&&;6=G1$2.</1=CA6)<'=B3H6":/9/'!;G2;+3:+"8&#)7=:9-E36,(;/3D074>=1"7@4>32GG8#5%
@r3949
CTCNTGANGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGANCGTAGGACTTTCCACATTCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATNAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGNAAATAAAACAATTGCATGTCCAGAGCTCATTCGANGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTNTTCATCACTACTTAGTTTTTTGATAGCTTCAAGNNAGAGTTGTCNTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAANTCTAAGCGGAGATCG
+
)%)!$#)++''&$(!**+"'$#$"(&%#+%+#)*!%)&%%$("&**!#!(""(+#$#"('+(+!'()"$!")*"*((&)'%%("$%))(*%$(&%$%(%"+%"()++!%&**"$!("!**%')%()&'"+%($!"*)&'*"$'#''$+%""+*"')%"$!(**$+*"$'%*""(&"*$!'+")'!+%%)'+$%*!$&+("$#%(%&#%'''&('(%&(#(!#**)&#$'!('#+!*#$%(('#"&#*$&$'+%%)$'#"&*)%+((**'*&%('%!##'+%%(*)%!&&&&*)(%'"**!$")!%"'*&'#+*+)(&"*+(%$+*)(('*)"&'&+'&()"!(!#%%+$&&#+(""#'*#+$&+*#"(%*"(")+!*!#$!)(+(%$(("!#%!("(**&#%*!''*+"#"'*'(*!)#+*%++(!)&*$+'"$*#(**(((*+&)*%"##"*##&!&$%)!+)'+++&+)!*)#&!%"(*(&)!*)""+!!!(##"$!'&))+($%!&$("%'%*$($'")*)(#+$!)$*''$)(#"*(##%%()(**$##)%%
@r3950
ATAGCGCCAGCTTGGGCGATGACTGAGCCGGTAAAAAGACCCGACGATATGATCCTGATGCAGCTGGAGGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGNAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAANCCTGAAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTNTCTGTACTGTTGCCACCCGTTTAGCTGTC
+
"$7F"E?//95?2%<C0*31,B-B5"H>F5,H(?+70=#)1D$+.?+$G9<2/+!%??'=#,,3E$-7'3;B5?2AD=4%2151/1BE@&D067$#=H-0"*%:A?F>5G6+6%G:F*@,D0!G@'/8&#G)%D"8E$B;/659<F:)C16?2H:+.85B"79$@BC*C38<7!E0?!4',(%9G83F==H!-+#F,2(B=+**(0$+#.5FC<$43@;/:(A+A-7E8"+.4)@:6.9D0#3'-8,&!44;8&+DG3*5E5C%>*00--:##8CC!H++9D,;86=.,=@&+56C7$,$G./2/F9ED@)6++;=4DFBB"+/".,&'#%%$=(<DH&B04<?-/A:+4.%882<102GA17&C&)*&B$F@%7%#5B2H)=31'*E;'G'6!2!5G-2&+1A9@"98+2"??CG1D5$=""AH8(=!@40/&-%(2
@r3951
GTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGNGCTACAGGCTCCTTTTTTATTATTCNCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCANACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAANATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGA
+
E"<F5@HGC8@57+EF6)C2."3+B-%=%+>)$2;5F-<<40($:<D0H"3(?-!16<B@.F-=-<+@=F=C99G,&G/7.865/F+6+#.+<6=-'.+"C4>&&B"H=E/&.'$A.?47)H4,:E+"9#ABA>2#%2/E870,"8'$)(/(E2#24!7!A:7C?,>=3)6/B*!6GG8DB<BG62-)GBC=3$3@1,,95:4-2HC)=<""()=H65?@9"GC#&E#%'($.G:'.DA)""9B6!0G'+C'?4@G=<#?),G;%)&#/:@!:$?-6<,&0"H2794-$8.+><<E&@7F)*92$"9B21<-;8$
@r3952
TNNCGNACGCCNNCCCNNNAAGATNCGAATTTCTGGCTGATGNTGCGATNGTCTNCACCATGTCAAACATCCACTCTG
+
&%"'%""*'"*""$(%$''%%""'"$*$*+%('%)()%&')#'&$"$"%$*"*)$$+%%$$%")+*&)!'"("!&*$"
@r3953
CCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCANCTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCNCATCAATGGGGTAACGG
+
*>H0B/H5<*9D8>87;3(.E6:6+5*F((&A.4B*2>C2/27"!D5;522D>B033E&E)'4>8A*<7(!')-<DB/%;:(9*>(";?6'-.3F/E<"'0*3,=H%+?4GFEG?1(?B35-!8*'H>A%F0&*#8&/;/C$2H-:5)H-7<37F=)2(:$.(D92)&&;8&=E#@31)A*=1234<B!:5B#=#3A<'C0."?DG,A40F:-./H5%9:+96?/=<#9D?C8EB>64#5!;FE%49!.3+(%H84#:%<8-5E/E!?'$BB3.C5:@0(,%G27@9#68G<@6/D4::A<4,B8F=-"9BB2@$(FC"37E5H>H;-"3566/25.<)">0+&3>'F*=+9)"HE*<F=B8HH%==DB/'7"$1.1@>@1++'
@r3954
NTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGNAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACNGCGCGGGCATTCAAAGCCATGNGGGATGCGGTGCTGNATATTGGTCNTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATNATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATTATCGTGAAAAG
+
#D0':%291:=>#?6=-%>-9+6:?*<=C#6BHAE?D.:.+!F;#B5296E6'$+9/!#+.E="1A+*6EF"=<E@)3F$*D=703(&.C78"*H;47@5$?@?$'7@#9%)@3D:/1#'(?)%=$%-F.H%07-!!&D6-!.*-1G1$6016=B?;'G+'>"$F4!8")8#E7GB5<E=/8=#F30E*.CAA>=&1+CDA4H-?.&D4@4:;B?!.6?@$6@3E/,3&212!1#7"!6?5*=G<C8<;A%-82>F+?>(7++B8D!40<<0*:HE<%70E+<)EF)A7HA)E7;(C*<F2.4.>G)#8=4711'B(*=F@(8>>-(7$;=/20HH-"@?"./
@r3955
CGCCATNGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTT
+
G+)3=+<.*B&GG)2E16B8EHG%3@4@8)C%/H#C5D>(#8)@G3-(@D.7EBA)3)@9<F5
@r3956
CAGTATTTCCCGCTGGCNGCTGGNTCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGTAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATG
+
@7/1G9,735%FE-+"9?BAH7@$H,$:)@!3):B5$F'2G*H;8:&CF9/$.#F'H+/64GF924#'<3::2E5@/:"=F94E/-6FF221H.<%C0FH2+;91A;/DG'</@GE)H=H!*"C46BG#9&:'B3-;3/@3."3(@>!H+:E)>E!C"68@!G$CF8>7+G+48F,$$%4=6"<!3/,-8B@;(H51H8"B7@/E--&*E,4H1,HCH2H5*FC407;:&!)2A*5?2=#;/285*3!&4>B46*60=@;"G),#F)@G046BB-=*C"1>.@':>3D:$6+HD5H<D@8)*!)%?+'4A4<*7#)0H5G%=!;,F!$:21;G(D:+;D#9!==:)5HF3882'$=;4G%D#1!>//':6C;;7':8?H*@;@C$C16)0
@r3957
TATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACNAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCAGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATT
+
.>%21B,CCG2@*/0,C.G?;3(7D)$EEB3E.0(*!EF'0;B>C52$;2/FEH#0+,"G3$964D&F)&A<+DC87>&E"5.E2+@E67&@84,H.$"66BA:*!(A.>2C1,EA94'!C,";4A';!0$=@?-FB4-6=&9>FF:-.-@-59G%/-&>A2)H:1>7#(C,/*7#10+<?44%6*,A)(C%(4/B,,'/#=-#1/!!$;&(*9!(%%;B()-(@:C4#$#F1:$F<@--:4#*;#(%5:GC%B,+'"*6.?&(8>HE'-#&FBCC#)1";!><D4!@(F'./<1G(/*2@'0F'E+D<>3,2>8EH+7(09D)'8)+$:@G1D'+4E64%'?/96D99C27B'B/:5051A*/>*:8-(73&9C:/25/)GGF$%8<<<;974B-G(#"#-6B6<4</%G
@r3958
NANGCCGGGTGCCGCCATTNCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTGTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCNGTTCTGTACGGGGAAATGCGCGTGNGGTCACNCGTGGTTTCTCAGGAGAT
+
)"#"!##+)(('&'+'%&!!&!#(!&)++((+!+)!%+'&$$!+*%%*"(')'$*'$))+&")'&+("+(+"*!$!+'(+++%%&&$$"+!%&*%('#%(!''!*)#$#)*'+#!+$$%'"*&%$&"++!!$+''"'*"&+!$)+$$$#*$&#+%('++!($()&#"#%%+%#+&*+%*$+())!%'(&)"*&$(%#')*#%($!"&)*)+$*#&)%$$$#)#&#%!(#'&%#+*'&(&''*%#*!)($!&%"$*+*'#&##'#!$&'!'!*)'&%#%!+$+&&()!('&+#&!!!*!!+$)!
@r3959
ATCCCCCCGGTTAACTGTGATTCTGGCCTGCGGANTCTTGACCGCGTAACCTGTCGGATCACCGGAAANGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCANATAATCAATTATGACGCAGGTATCGTATTAATTGATNTGCATCAACTTAACGNAAAAACAACTTCAGACAATACAAATCAGCGACAC
+
1.G5<&>%-79?')%=#?GA?6@602E)2A*EB.0">")$:A,5G5,>>8<"!':#900-@*3">%7>4?F;C=$;>;68!#&50H1%4B<B%B8$F-BCC!.6>0/C=>=E)*55B(*"8+9*GC9DB>#*"3&)C<F$'34=<(E#'8;E9,)6B=G7:+G=%2@F3)<6.)F-A4@+%)5/CE)E=$,&-=0=4;7G.B5.35D;4,8200251C-)$F)A;
@r3960
NNGNAGNANGNGANANNGANNGNNGACNCANGGCNAANCNNNCANNNTNTATNTNNNTCNGNNNGCNNNGNCCNTNNTNCGANTNNTTANTNTTGCNGNNNCAANNNGNNTNNNGNCNCNNNNGANANCGNANNCNCNCTNAAGAGTNTGACNGANTNNGGTTANTTNTNANNCNTCNNNNNGTNNACNGANATNNCNNGNGCCTNNNNNTGNGANTNNNTNNNNGNCNNTANNNNNGGNGNNNNGNGTCANNNNNACNNNTNTNNNNNTAAACCNNNNTTANNNNGNGCTGTCAATCGNNCTNNTNANCNNGGTNCNNAANNNNGNNACNNCNNGNNTNGCGAGCNCNTNAGATANCNANANTATNNTNGNTTNNAAAGAACTTNNCNCCCNNCNGNCACANCNCCTGNCGGNNGNGGNTAAGGNNCNNTNNCNGTNNNNCNNCGCTCNCGATANNNNNNNGANNNAANCNTGCGGNAANCNGNNATAAANNNNNGCNACNNTACNNCTNNANNCTATCCATNNNANCNNTTNGNNNANNGNNGCNNNCNNNCTNCTAGNTANNAANCNTNNGNTTNCNTTNANTNNACCNCTTAANAAGGANGTANANTATNGGAGNAGNNAGCTNGGCTGTNNNNNNNCTNTCGTNTCANTTNNCTNGTNNGGNNATNGNGNNTANNNNTNNAAGNNGNNACTNAGCCNCNGTTNANNTGTTTCTCNNCNNANNNCNNNATCAT
+
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
@r3961
CCACCGACTNTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTNATCNCTGTGCTGCTCTTTTTCGACGCGGCGAACNCCAGGGANGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCNTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGANAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCNCCTNTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCANCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGNGAGAACACCTGTACCGCCTCGTTCCCCGCGCCATCATAAATCACCACACCGTTCATCAGTACTTTCAGATAACACNTCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTNCCGCGAAACGTCAGCGGAAGCACNACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGNTTTTTTCCGNCCTCAGCGTACCGTTTATCGAACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTNCCACTGATATCAGCATTTTTAGCGGTNAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCNGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGTAACTCGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATANTGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCNACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCTTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCNCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGNTGTAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATCGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTCCCCACGCATTTACNGACCGGACTGCCAGCCTGTAGTTCCCCAGCGCCANTTGCGTGAAGCGGTATGTGGTTTCCGTNGTCCGGGCCNTGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCG
+
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
@r3962
AATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATNAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCC
+
=++;*===#8$<>5*H@4+)'*)!)?%6&;69#9C5!A8B19"6(C7,,<-;DE:.E0/3;#%5H+-'"==(5F/D&88.C%DGC-F!HH*>25$4!6:C5=2/E.@&:B2#D@8E#C"&BAH
@r3963
ACTATTAAGTGAAAACATTCCTAATATTTGACATAAATNATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCNCTCGTATCACATGGAAGGTTTTGCCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTANACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGNACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTNAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACACACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTNTACACAT
+
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
@r3964
CAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGNTTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCCGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACNCCGGCTTTTTTAGCAGTGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTNGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGNCGCACATCGTTNCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGNCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGANTTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGC
+
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
@r3965
GTTNAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGTTGACGGGTTAAAAANAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGNCTTAATGACTATATCCAATGAGTCAAAAAGGTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATNGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTAGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATNACATTCCTTTCCCGATTAAAAAATCNGTNAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACANACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGA
+
(!'*+%)#!($*%&')+$)'#+#("$)(''*$!&'$#)''%%*!!"!+&)%*&'+#')%&+#)*%)"+%!'%')$)*$&)!)'$"($+)#&(#&#$&!&)+!!)'*"$&+&(&+'*'*+&%+%)$(')''#!'("!)(&")'&*$*$+)%&+!$'!!++*&%+(%&$!*%*#%%#*$!#"&+(##%"+!!'&!*+'(*&$!$+&"%#$$'#+)%)*(&)$*&%"(!)%$'"!$&%%''&)&(!)#)##"'!(")*(#'+$$'!!&%)!!*%"&'*#'##)*#*('%+##)$(+)'"(!##*"(%#(!!%%"')+$"$+)'*"%+&$#$#++*%#(+!)+&!(&!&(+&(!#"*'+#+(%!'#$($*+*("#"+!+%%())$)%)*!)')$'&%#(*''%"'+*#)")&$!#"'(&'(#+!)!'*#'!'')+&%%'%)(")#(")*#)+!$$)$#")&+#!%%'*#$%*%'&*)
@r3966
TGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGAGGAAAACGGCGTCAA
+
BF!;?AD?<B-32H*@-EF"2$A&A.0E)%$<A5@AG!2B>.F@@>CC&=$*/84!!>9+%=%&-A2<(4<=(<8+@2E.3@40@*4,E:#2/):<%=2##<7:=6;A@C7297,-B1$'<90
@r3967
GGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATAAGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAANCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCG
+
6EE?.&;)H&BG"1*&6$!3-2E*2H%HE@$8B@40&@/06/5A79;+*8?452312D.7"0,8>00$>9(.@:CG;;'D$:7%/C#$<<H<5$?50""HG('2@.H'3?):'9EEG7B<:03D5@55A=$+<(H%E$*0E-89F;:B++DG55.<5$,=(H&EC>$6B0<B.$&/24>'1!HA@F!-17&,?2;0'2F1-&E)-=*C%F,,!%GA2%7*>@D;EH'9#":4'&#".6-9#E+7@+5'@$5H3BH+?";;/7'%'330B214-$5>0+D60'%3AE9(G06""/43C@;>G&:"
@r3968
TTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAT
+
/A%/?"GF.*507$B03"*$D5)=30&F9,?*A%&/791DD31+H;#:;4.7@/4&6)-""?2=&<%0E!83>!&.25!!@%"&!G%E4F/;1:!C3),02>$78D@6>GA6E<1+=#<..?8+BG3/D,*4='/G4FD";"-#".&4:1-H#D645(/-
@r3969
NTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTNCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGNAATGCGGCGTTA
+
"B#";%':*"32<E@F"H'E?GF,*HD43"2.3%D87$'72$@AC4+2.?E7/<E)6=13,5,<GC9,'B0DB"HE*#414!B*#0+;!!(/4<;09+&36<%HF"86B.&)*38C,B);=!7(>%AG+7@A0)>HHG/G'!6$@+/A+<7/1"75@E:F8&*#4=FA*G8$0(#;'&288"44#FF<A
@r3970
GCCTCGTCCATTTTTTCGATGANCTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATTTAAGCTGACTTTATGNCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCANGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGCAGTGGTGATGACGCCGAGCCGTATTTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCCATCCCGGTACGCTGCANGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAANAGCTTTTACT
+
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
@r3971
TGAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGANCTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCTCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTA
+
!#)>9>928?+CG>6>*=?F1G8.#4;"A=H6B'%-'E5>>-.&03.(C(4&-2/9B12%@*0!1='A*,*(2/!9!-(A@?BH(E4B?%G9FCB1EA%%.C,E<>?:.B)/F>##>8$<A88,D<-F%8.H?:=-8#?:D'#F&1.G8?D8@<>@G@287E-%;/3,%6.C:;*@&&+&F07?=@4<C4#<F%70F.04H<A;!%.E"=EC+*<:>F"#.'H$3&8)3>=DHF@A3,@9(/%!575E7B3=7"$A7:)'C!@40-+02D,>7-47).0E-(%?.+>.<><72!</=4=61%7C&;56!+!4%!:F+%>:(863$AGA@0E#B4,4,E1&)E/3H*-,4467/?G6$9'B%"0>-+G7G##2BF
@r3972
TGCAGGTTCAGTGAGTCACCNGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCNGCTGCTNCTGACTGTTCNCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTT
+
;:-(456A+5FG3&"'*;FCH3(-G$.9AD;/D(5/%B%GFG3,:$=&74'8.3$(;&>E*<6#?G84%)GG!69*BC#150?F=8C@H!3?3%!&B4BF'4?"*@%.#.4#:"2G!A9'3?2?B(/8&A#;G9@,@05,5)/?&AA7#*EH9-H;1,B18!:&9;(+F,EF$H??G&H$@B8)7$!2.0*<65:=1;H<%5(
@r3973
CTTTAACGGCTGATGCGCGGCTATGCCACCGCCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTNTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTNAAACCCGGTATGGATGTGGCTTCGGTCCCTNCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATNCTCAGCGAGCGTCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTNACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTNCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTNGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCGGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGC
+
''+$#(++%#)#((+$#)"#*)"(#!'!!!#!%)++'&%$$*&%('*#+%$''$$)$$+"%'&)$($%(#%(*$'+'$&"&'$!%)%')"*!#$!&++'#"%*%**"!#(%+*"$++!!#*$%*&$(')''"&%('+'+)##))!+)++')!(!!"!!'((&*)"'%)'+&&)$++)#")"*&"!&#*)&#!)"%"$(("%$"*$%"$!!*+#%)(!(%()%#!+&(%%"+*"&#"*!$*!*%'&!*'*"%++)%)")'#)*)+"*&%**$$*(!#(!(+%""+**&"+++$*+#%#"!*"'#"$#*$$'*'&'")$**#(!#$!*')"'')+%'""*'#&(&+*(!$$%)(((!'!%##)(!(%&'$'+%'((()&)""!*+&$#!*)%$()$#&'"++"*!$&'!'(#%%$$)#+("!&*"+&'++)!("*$#!#+%++)"%*+)!#(*)"+)#'((&&('')#!+(!((+!"*('!'%%!*(%##)*#*)$&&*#"$!!&+**(*$"&'#%''))))(')%%&#)"++$%**&("!!(+(*)%(#!$%)+!#*)!#""+#$!*"*&$"$*&'*+++)*$!&#'&()%+*''+*$+"(#+*%!"&%'&!'$+($$$%'"('+"*+!'$&#!"*'$$$"&#)!(+((&*)%*&%&+%'"$+%*&'&$##+)+$&%"*))!)+$+)++$"*$%$"**%)(()*))#!+$"$"#%*((#""###"*$*#!')!")#'&(($(&%#)")+#%!*#$#*++&('&!+&+')"+!#'))(+$$+#%&'*!(
@r3974
CGCGACANGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATNACAGGTAAACGGGTG
+
H>&C%G<*DE-6D"@((3GF407'#+9+!044"=%88$?H;@(@FC*4G;0;538?"0@AF2))(
@r3975
GTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGANCACCGACTGTGAGCCACTCCGGCC
+
.867,9C9=>-<6.$=#)94(;(3+7HHG3)F!E<9E,A@(7(".&;64"G"!F/+8/0./%,5=<7"$7F73.0<:E$C?4!5/6,;'CFD!=(8C#."!#'GE2<<B>F67CC5@A$<H,BG6'*34E02<)&<<%G(>&"7HG#.%.'5%>')D":H7=-A1FH6!&&*')G/!A5#@@-7?$AD",3=?@7$!&)DE1%HF"?,7.$B<,:%C+1?
@r3976
AAANTTCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGANCAAAAAGTTTGGGCGNTATCAATGTTGTGTAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTANCACGAGTACGGTGGAAACGATACTNGCCCTCACTGTACAAAACAT
+
&$$!#)+#+"'%"')#+%)((+$#)(''##)&")")#%'!+%$%+'$##!$'&)#"((+)%)*#+%*$%)!&"!+*')((++''#$!+%%"*#*$$#(%&*#)#(!!+%(!'$$"$!'&'$('#"+$*&#*!$'*'#!(+!&'($!&+!"!+%'&&$'#'(&%+%()%("*"#$"("#("!")*!!%!")"')+!%&&"#%#('$"))#&'&""#*('+(&%"")!(&'!''!&##&)'''*"%)&#'%!)#$$%#&%!%$'($*"$!)!$"!##+*(!"&)*")###(($)(*&%$("%$+"('$&*"("&###(%'#'!!)&*+!"##!#%'#&'(*$)!+!!$'*#+"#$+(!(+)*!'&
@r3977
CTAATGGAGCAAAAGCGACGGNCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGANTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGNTTATGTACCGAGGAAGAATGTCGCTGGACGGTATCG
+
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
@r3978
NTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATT
+
!=!!:6D.$,A$E9>/1&+E<1.2!*66AE;.(<28)<B38@33EF@7;@'E$D1(4(G
@r3979
GGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGC
+
&/BF.BC=)8%'0'C0%@6EB6G<,4HBC8A":<C05=18)<%7H##7&")>#*5'#1A<.B>%A$@==$(,12=AD<AF0G,*+&?F>/==-1;%3'&$$@,)-BH8#A:H1)3%-'/'B'<B>*.E(,+:?$@57(8;F8HCDC@4FF"=&>F(?>/A?0%C<B7.F-<=%H%(&5#C)&;?4;,?@A08,=1+''B2$F'8.:"?%&=)4-6&C0,-+)E5<B0=!/*
@r3980
AACGATGGATCAAACATCCCTCAAATTGGGNGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTGGCGAATCCTCTGACCAACCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCTGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCNAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTNTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGTCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGNCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCNCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGNCGCAGA
+
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
@r3981
NTTTATAGGCATGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTNTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAG
+
"H$93#?HAF4F4@D"3@..'$262$/D$D.()F?*B.A-:1F4DFF7@@00$++G"A083%B3)C2F&G0&05?>G329@'B)=EC/':+;=,..8)"B=6&-$.*A,3'=9'7&B1/B>F;,!@(@4#%#-/>-%8)4D2!''C/E-9$1?3>
@r3982
TNCCAGCTCACCANNCNGNNANGNNGAGGTACGCCTAACNTTTATNNTTNANTACTNC
+
)*&)"%!"&)*'&!($$&&"&!!!"$&%*"#%(&)#**#!)$#$$"#'!%###!))$'
@r3983
AGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGNCGAGCGTCAGCGTCCGGNTCTCGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATNGCAGATTTCAATAACATCGCCCGATACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGNGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGCTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTNCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACNGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGNGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGNTGTTGCTGTATGCCGGTTTAAACGNTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGNTCGACGGCACCTG
+
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
@r3984
NCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGAAATGAGGTGTTAAGGACGCTTTCATTTTCNATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAANCATTTCAGGGAGTTGACTGAATTTTTTATCTATTAAT
+
%<+:>A+9F9CH-4A657*&C9B1*C&'.HDA<.8:<9BC";$D?9$G;@()<0"*E*>C9<7:H0@((00;@6,##(?*:=@D"+G=9<!.4$46;%C437241:F.?":0@CGD'1F@89G"5=A='!D&/?!!;=5B0)A'#=2/C41C(:$3;%9@HG&=@G!FC,7$?74%A:781+C!"8DE%,D%D>DG)"',(/*=$$GDE>=D";G%B20'3F.8,>48'&1D'93E>#='(C9H5H-)1./G29'5:FG0))#13=;6A=9E&/':49'E4E57(D<?BG)%86'37-)<156)""$+B;5@26-H"/!HD>282.<,!"*+=4@4,G0(958H#@G-<93*/F08@3$97+.=D<E&%0/G/G2B,FG?H&G;(!:(!#3B>B8E4@9>;40F=
@r3985
CTGGGCATCAGCGTGGTTTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCA
+
9=D&13,"/5A;*7*'B6%7/.C5C">4F:H'8>8B>=DEE)B4@B$/-62"4@D#DA'*B+=CH*-$F#2&@!$+A+;>=$/?G.-A,+DD)8BAA9GD+#*&H:,9<F26<@@?B)>12
@r3986
NCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGNAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTA
+
)1.=E=HHH<+8*GF=>*?C+E-?"H#+$7(A7<2CD6%",+<#"9+1B=&0(('EG70%?.?#5C4C,9.D33=(&85.C.;GA<?F+ADE&1>@@D7*(?&5((00@D<3GD//3:/1;*#8H"HD=.11)G2D,?E0
@r3987
GACGCATNATAGCTTCTGTGCGCCGGACGNTGCCGCGCTAACAGGCGCANCAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTNAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACC
+
@0-7!?#*98)=7&&8-=C,#/?995,/34#24)HH8-/.!2A%)9;1--9=@&$>",9@+#BC0(;/<.D)3";2+;D4%?G7?%..'2+C/.8?2C66?H"%H8%1>!/#;<E=H>/!>+&&#2?"F<91@B+C<CE41#AB?(C6;:34;98#C2:/)#304ED/B,8&5?7#F0!(:.63#
@r3988
GCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTCCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGC
+
*C=$.(C+BECA1A:2@BG3'?H+2C==!1E*2'21B*.!&?B0*5%.A.9:2-'302).<4@.%2<*&)@4C6@>!&&><1GD7)5/,6C91:2?1'%+)?A7-F9<1B-@&>;-FD&):,5,/'$)30(.;.64&%B?
@r3989
ATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTTTCCTGC
+
:;!?2-;?,1-?"G**'#:-=/,H!=0B*+6,&9=;$8FHF>$%!6@/+>!7%=&F1*4H5.-D(24E,8/8;)@=5*G4BGD+/$D9,+HH=/345$(:(+?!9<#D5"6E,9)$&=6(78;:
@r3990
TATGCTTCAACGAGCATGTCTGGAATGGNTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCACGTCTTTGAGTTTCTGTTGGTAATCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAG
+
(C1',#7"0F'(77>3'%F=@93E@9*H!A:'-?B%@)&1<:B;6B+$G86H/>%;F)%A'G739;'#6$=?."8>2+5!.757+D1AD7>#371?<E=1=*G""'7(73?111EH?@3''-717+"=D90
@r3991
AGGATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGANGATCCCCATGTTCAGGGGGCTTGCCNGTGCGATCACCCTGCCGATGGTGGGGGCCACGTCGNTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGCCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGNCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCNCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGNACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGAGGCTGACGGCGATGGCTCGCCAGTTCCATAACNTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAANAGAACNTGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGNTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGNTGNAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGNGCTTGAA
+
#!&(*+'$$$)#*%'$)*+&'($$#!*'$&!'+!!!&#*'$#'+!)("*)('##+*+#&"(%'#!$$"))'!""%#+'+$$'+(&!%*#)($#)!&)("*+!*%*)#*"!')"$(&*)$$#$'"&"+*)#+$$!&##"!#*#')'*&%%+&)*))*(%#"""')!&")+))!!&#$%'&#)**&$$!*#"")$%#$(&$&'%++)%'++(""!!!#++*#*%"'!$%&(#(!#+)''#*%**!%%#$('%&(&)""'#)(%&$)&)&#*+**)(()"*(+%+%*!%$!'"'%+#((+#'+#&"%+)('"$++()!$)#')%'*!"%+$+++)#!%%###$!)&('($%*+!*##&!"#"#&'$+)'(&(#))(%$!#$((%&!$!'!&'$#''(*"&%$)%%)$&&%#&&*)&)'$)$##%'#%*(!")#'+&')+%)&"$%#*&*!(!##&%+'$!(+)!)"+'+'')+)"$+*#"%%*%+)+!++$#%$'+)$$%'%$$+!"'%%!$*$"*$#")#&#&##(&%%'(*(($'&#&%*$'$('*)'++'$%'(++('**$%("'%")#"!"*&)$&(%&(#*&&%))#!!(*%")"+!"+'+)!!")%"*&'*&()$#+)##(#"*&*'(+%#*!'$%%'+$)+#*$$((#+!+'*%'')""*("%)+(##**$*'*#'!**%%%'*("&+&!**")"*%+*(#)+)%($#+%($&'**+")"&)!#'%#&+%"*+"'+""**+*'+&!&##")$&(&(**))$"*'+#*!!$+&$#'*%'&&($&'(&+('#**!&()*!#%%$!"*'#!*#&)(*+$&(")*)*''($))($$')+"(!&#%%!*&!)"&")$&'($")+'")%$$%!"&'"$&#!!(#$$!"%&(+*#)(!!)!&#
@r3992
TNCNNCGNCGTTGCCAGTGCATCAGCTGCTCAGGTCGCGGCNCTTGTGACTGATNCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAAAAGCGGCATCAGCANAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCNGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCANCCGCCACGTCTGCCTCCACCGCGNCCACGAAAGCGTCAGAGGCCGCCACTTCAGCNCGAGATGCGGTNGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAANTTCTGCCAGGGCGGCAAAAACGTCNGAGACGAATGCCAGGTCATCTGAAACAGCAGCNGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCANCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGANACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCTGAACGCCAACAGCACCAACCGCGCCCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGATACCACCATGACTAACNCGCTTGCGGGTAANCACCCGAAGAATGCGACACTGACGGCGCNGGCAGGGC
+
'&!*#'()!"")*&%#$++(*'#(($(''%'"&$**'($$*%&("&%!'')$)&'(""++$!#!(+(+##($)+$&$')%!$&$(+#*&&&('&)!$(#$('+!!"+!!%'$++#)$$*)+('%)$$%%!$*$("(+*")'((%"&$&(+!"&*#$"(+$"%+$!#$+##)+%#)!&'(#)!'()*#"'+)(!##$+&'!$#))')"'$'!+*%$*%&$!&#+$+')!**!*!#$)!"&#+$"$%**(#&'$""((+!(#!)%**'(%#%*+")&#!+(#()#)+)#'!(&#&)+%(($#*%$)*&"')$'$+%!)#""%)+)&!'"&('$"+!#!&($%)!"'*)"&))$++&('#)(&")"(*&($#*)$'!)!!'##&*#*$&!!)+!'*!"!#!%$%'$'"")(('(%))!%%%$+#+#$!)+"((&)))&")%"!"(#+!)+&#+#+)%)+$&*&!#+&&(#+$+"&!$"'%(%*$&%("#%#'()&!"&))*+#+$$"!##!'"$"!!&(&%'!"+')&(+)%+*!)!**!'('&&))+!"!%)(())(("$)*)""*"+'+$$)!"!+%'"+!$($&#*'"$*%"%#$#%$&+&$!$((*$!*))"&!$*+*"&(#%#*)$'"+!)$)(!"'!%""($!*())+))%"#%%'"&$#(%)"%"*!"#&#(&%*"#!"$$'%"!!%)*)!(!$)($"$%*$*(&"&*%(%*%%*'&(&#&$!"!)&'*&"'""+$&#%'"+!*'%!&"!)#$&*$+!"#(((+)")'$'+*)')&)##%'"##%("("""$%+!*!$%+#('##+*'+)+!"'#*+%$+'!$%''!*#+##%*%'&(($!&)("&%$(()""$'*(!*!&#)!!'*''%$"$%$*"$"!(!#$*("*)&')*&")&$*)%#((#%$#%$*"*"'+")%'(#%*')#&#+)$"#$$$((*%"'"%($#%%)*!#+''&#&''&)$!"(+""')$"('$%#$)&*&)&'!)"*+$%!($&%"$$&'+#"&++)%!)("!("+!''%)#&%&(!((#$(*!&#'%&)""(*
@r3993
CAATAAGGGGATTTGCTCTATTTAATTACGAATAAGGGCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTA
+
FA6(F1.*BA23F>815;F-,0B<B7*#1D%'58>>EE%A3*=H"E$E8E=D!DA4B40*B7&A-*#C',<!DH25AC
@r3994
TCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGNGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATNTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCNATACATTTCTAAANCGCCTTCT
+
A'F8)&65;*,8/51/?@7!"5#423?;#.-$0$.F&$!?3H7!*0FD>/>".>>7B!4:6721<EA%B=:/3='721@"<"$,"D>B-$;"GB:G<;"$F<$+!>CH0)14@G2%+D""1$),/BGH'"")+-8$:CA+>=G(7E9G-52;''(??;<$>97)#;H';"C.H/ABF7,+D*?4+,9C>"=>D!G*8:GE+8)*D=GBE%?&5'"/$5'G6)*?.:8'"37C2CF-C,HG-B6G?69&$5E6C!&258FD;$=HD6)"";%70H>E6>#CE.E&6!=:(&-G$G"7:(0?5G=+47/069#&B0D7-<*:25""HB:0093C$;!351
@r3995
ACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATNCGACGTGTCTGCGGCTCTACCATATCTCCTATGAACAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAATATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAAGAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGNATAACAATAATGTTATTGAAAAATGGAAAAATGATCCCTTAATGGCTTGGGCTAAAAATTCTCGCAATACGATA
+
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
@r3996
TTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTCTTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATATAGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAANGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGATAACCGNCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTA
+
.4)(@;5&"<(A02+E#8>-69$E</)D7F!)7(;>28,7%E2!@<+<D?F$.43?&).D0.;C#:!5!>,)3AE;:?3?H>C!?H080$6#-'2))/'67A8:FD%G%<..3G3=?402-;$%8&+,(E2:$;=--2D:=6G!."A'4&.=?!0H/:"/1H5;E6"1/-@1;DD%"%.(,C(B3GH?1)+4/);4H&/B-)+=8?)3-)C,C5*G2>B)00AB:$(?1B85<1>$'-@9>FE*C*:!'>>'6F<=+9+5D57+1+AA,DA9DHE$=!.3&>G0E,;1,DG52=D?8<*D$>8!;(7=F2.80)F)G0"7;6?3G0!%/@>78/4B4'&D99-23G-;;B+3.#)>'D0313G.',)2B?G",.;/#!"5H+:E>FC/,89->B-!28-)/DA*'.B#/<<?!&"!,E:.)
@r3997
GGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTNGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCNGTCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACCAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGT
+
F@$=E9'G,7*AHD"51A-#F4B.@>F"'4B>A"3H37-2)5$A%#(:'7D,82/D<E/';/.-1#5=E(#?G9GE?)&?-$F*#>D($#G(.%7D@4,/*2.G8<)*D22@1-=;C!"C!G=:A:'.*()+,1%.1E>-!#>?(?2?&0-A7?6'D776<E+@B!2C-*E5;8-$%EB9F"7?1&HCHC4@5'EFH&8.0A33/6C:3!BE61@,A*;=,:'/#-:0:57#4,#07GH957C9+68$@/",$F($5',CC'@(%%E;&G=+!$4B9#$HG*C?G5<#/@H@;6#"1DD#=99'%$:A>0.H<%)#G;<&1>F47,B:13>(9G)A,@"H)4(%87#/
@r3998
AATCTGCGATGATGACTAGGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTG
+
,(G0D-*6($#%&F&,G.B;'./&D/E+.-1+0F3?3;1*+!AB3.%2#B3@/6(
@r3999
GCCTTTGCTGATGCCNCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCNGGCGGCGCGTGCTGAGTCAGTTGCATCAGGCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAANTCATTCAGCGTCC
+
+8#;:)DCGFC58C4<A33)43)9<H635>>5'#+'(B&5=+"8.!6D.*HB902B*G@E9?),:*D'--14239-%+15)(CD@#;/9.>0./1E+3'DE946"@8!!!!E=):>3?0.6E*=<F,>A++99/(C')DG*:""E.F&*7?,@"4='H$#7GH.D@0F1&>/#?+.2>AAF=#-'5'?6+H$GE589<5$>D>51FFE6-9()/=(;B&.!(A(BDH+.(E-*1.'G':A1D?:B1?)85$1=->84GG%38B&E;H>@627)#?7=8CF<9F>-6/5'
@r4000
TACCGCAGCAAAAATAAAGGGANAGATAAGCGCTCAATAANCCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCTTAAAATCGATGGAAAAACTTTTCTCTTTAGCAAAACAAATGACAAGAGTCTNGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCTNCACCATTNNTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGCGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTNCCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATATTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGNC
+
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
@r4001
TTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATANTTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGNTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTAGGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGNCTCAACAGCCTGCTCAGGGTCNACGNGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCANG
+
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
@r4002
CAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCANCTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTCTTAGTGACCTGTAAC
+
3A7@.8-#ADC5-8:*D7':#2?!4:E:*6155"$4@=G@D>0@**%>+D5&A:538$%/6"#:H'83"6C+D2%1<,4!9%&6:FH!:81(<.=)?G(F;DD<4""5!/+886!B!$!$0H%-,=G!'.+C05>=F=C$6:9C5?.%%>%C3<D<B8",506>3DG+6??,&3-1;:,:0&-5GA0"+/;%)"'<>+<>5-%C9H2%1(0($-@=H767(3>D(A(8>>
@r4003
GCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGGCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAA
+
H??B@98'."7?0"=8;@F+:6FC=DH$7;&49AD'0C.0&G%27.B6-.D+75.',=.*.D"C'GF1?:=3-<78"//-;:!()$*D!<'5H&B19>><92>E1>4+8F3%)*H3!.%+.@@1;$%!6)C=@($)?)<."D&<87;%(<A/(2AECG&2E',H7+9?%4A050%3:H?27D4;:B&>@;.,$3DH&8(*<+,9:6;%?)5;73#,)6-A!$*-#6<4)09!9EC%*>%$#07&?;#7FGG<H,(.*#%@D@A>G$5'%C+BH-B@BCF!#HBC6('A1H#2.D!G%;%"*.9G6.9#<<>;5<6H8G:?!2?4"!3-:%&:))+C!7>G-,-F&$"/<C=.D*96F/A(6!.CCE@789B=?2?A1D"H:%DC)&A'>9(0*!6=+%?!";<5>F63'5AH
@r4004
CCATGCCGCTTCAACCGCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATANGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGC
+
E=.&;9@->0G'A2?.)-16FD$GA,@:)H&'.<=0<3>H<>0)HE<#:3!"28&9E(@E+0H,!#D66&F.$5"><AG(.G5G2<C&*;3:.-034=293#)&C,@#&13$.71*<(*2GD1@GB%015GEA/$(2.$!"=1"*3H'71G&(2A078%:6;3,!2='G@0%D'=1><2)6:%?G</506&H83E,6A(*9&$8</!*6*/>G>?'B="608%%790A;DA1#=A%'"8*4C":<86=;4/1<-H);"&;$@B</706+(!FHC'F$1H<'3
@r4005
TTNGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGNA
+
**)B-02%.2/:%:6D':7(?"%)4*C)%F+#$=@D%<$$58C%E09(,A614900-(0?2%B+E2D*($"7@6F<7=73.18@"-9&73!7'1
@r4006
ANGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCANTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAA
+
4;;169*)22B(58D!50)0-$B3#-$A#2&'4&@CA)81''3E8&A27A@40'@8840!3BC8?!=$*)-?4D65F87'(D.-#%,<(1-:C#@#52:D"-#8*5'-)94";*E)=!90652!>E!,&5'98A1%;;"30(D$?8$6/?-+)+#5F;7C-:>;<=.*08C?!8*'D!?!:4(@F"9<@-)A;4&C;-<,D,'0FA+8+<;,@.D"!(9FF++:*G&0@1*,$;#1GB*4"8?#!,%7B>:<//BH@.?*4E?$;>,FA0>%6<,2(9)F0$*H&4&?=%%4D)DG-&+'(4F?-#<@A.?8!0?;+*"H>">
@r4007
TTGCATTTTGCNGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACNTCGAAGTGACCAACTAGGCGGCATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCNAATTTTATTCAATAAGTCAAAATCATGCCGNTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTG
+
?1*>*%=;DD@:+C!1#2G*)H)/8DG".E3<C-",8=5)46'*F.-;/9+97.8-0+-*'A!:D#E6+=!6368E/8=7+@-?'?#.B3$*05D(0&!-;71.0E4?:,*)F&.'H7"-0E>9%$>'5G"%)C5F$"(H2=/-B./;../2+D.F5,81D'8%*HB+4@7@>@+6%D%-4+&$3>:23/==>#-)G1:G8C(;-F@#'+!??B;,'DAE7
@r4008
CCTNCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCC
+
6-5C;=G0:<D'HE16(,;G23(((E.,FH>,<3CF)"%!2+5H;<*87.'=5FE<$8$A#
@r4009
CGCCANTCAANANCAGNNNGCAGNATNGAGAANTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGANTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGANCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGNATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTNATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCGTTACCTCTTCCGCATAAACGCTTCCATNAGCGTTTATAGTTAAAAAAATTTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATANAA
+
($')()**&(!%!($'$#"&((*")"!+"&!$('&!"'%)'!%"%$#$&"#'!*#&%%(")(#+!'+&"*)'#)&**!*+*#$$$$#+!"'&!$"#()%#%+)*#%(''#*%)%$(&'$($&'**")!+($"$'(''$+"(+($(+)&&)'##"$&*#*"#+'"'(%$*"'$%&$$(!%)!'$)$)#')#&+(&&!#!%$++)+&''%&$**#&##"!!'"*'%*$&+!'%%&!")*$'!"(%$&"$+""#))*%$*)&!)(*$)!)&!!"*'!"%#)%&+'()#&($%%'+)#"+$$)#*)$$(%"**$%&$++#$(%$++'$#*$*$''+#%(++)*'#+%*&'%+)$&+"$!&'%'*+%'""&)$!*)'%%(!$%'%*"(*&"#!'&#$'%$$$'$&'!#&+(%%"$")&)#"$(*'")('#!")'(##$##''!$%)#("&!%++*$))"+*$!#))%($&#'%&!$)%&&'()%('%#'%"*%"("'#&*+("(!'*'%%
@r4010
TATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTNAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGAAAANGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTAC
+
D%4$?540629?)AH;88)06!'(76;*4E9:8D"49B5EH8H:#<8;82G=4+'-/-BC::;)%;*GA-/5+2=<;%;E5%2,$/EB30#-&2$-&?-7G+20;5-0";+FB//5H53*(@6;*E/<&0=/FC@F9=@"2:"#/,/:CG+24!5@G;@%>?'DBG6E/-((G!!<+&G08:&@+<C,$$=>A8#!@:&&A*A39(D>H-/"G=:1>6$/@&6#&!.09=%@?HA
@r4011
ATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAATTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTAAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTT
+
(5$:@!F%@"&.,5D43>+&)&>,88$?21H#1D*6/=A18%6@-,74&@<!#A4B1H:-5$+.94%247++;;GE2<,=6C,07:,8C3&$%+*:.*"9C&;("1(G:6)$&D6>@5@;BA39(<4E,/EF&3:%H!?14@"=4A)/?>H#17C%D8>))B?B'"DH+%;+FE?:/;93$FDG?:C9:.H2<6@,?%B77"50GD"'-8DH%0*7(=&-/34(2?GDB74A52*3-7&@!073AG7F.;$7"!9!@6F$?EF:F,8@#;;;<-.1'D5H7E,%,F;F4148$!1'=HD61(<4?+!!%!1=1>>%1
@r4012
TGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTANAACTGCAACTCAATTACTGCAATGCCCTCGTAATTNAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAANGCGGGATGTTCATTCTTCATCACTTTTAANTGATGTATATGCTCTCTTTTCTGACGTTNGTCTCCGACGNCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGATAGGAAAGCGGATGTTGCGGGTTGTTNTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATT
+
"*?)F-%58H<!50201=F6G7?!("/CF"*FB/FC,H(.'1473/(9/#581./>206%G,9)6*=)DE#3'>?*AG?703(-7=7*F8H&8E<8G=/=9979B:2@-#!*;G*D'"1!*+:.=22;5$.?!0G6G2:3>1=2)0F5!-0F.46(.32E4&7F/3!&,25H*/A2GE9B)B#055'**C18AC1*=E5C';D@/.13B>C!8/E0B)3E7%E3C=!.6904>>(8.0,6F-D>*(7G-=F6CF=+>7(04"(65!/HHB)G9?%#%7"@>C*)#+'!B!0,>E*D*<C6#F;.>>E'AH4C%>C>$31#27=:1D'E/77DH./'!26H)GH1CG54,;5'G!=2=DG#B6%.(".C!).99;?G7)-(,9-E*E&)G9:A%9D-A<<6@("96@6:12?G#919(&CA1>)("!.4H<C(H8-)F;*73(;#*B@';--C"&0194,B17=00!01//@6&B@>5A65?
@r4013
GAGTTGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTANCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAGATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAAGCNTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGACGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTTATCGATACGAAAAAATCCNGGCCAGCAGAGGAA
+
:B.@/;-<FDG'A@<87/>+0"3-A@1:(?$=$AE"8:D9=#:.8A.B-C($:8G<A&#:F4493GF=<H:FH0;'11D7/B%!+B)7&CB(5F=87"#*D>"#;0(9/-/6<6:&-$/(G#?A<81B)"$H39F'+*E$#G7B:<4"1CH$A#(@6@470A@0'!G/A&AB#B$<!E-5GA@"//43<CG!0;A!0<B3G9E:#>/'6*%-42<G$8FF8+):!6C3>E,-%A4-=>-@<;/%7<6A"G6BF?./A1D'60ACB:8.*H(?@B2.D5.#%9$8A=8C+"=E6B*H2FB.;*$((=87E0E;=4%9H&FF'$:24%EE6>6<G%2H#4)530%1D%&""(@DD61A'#<)#&)E<$-5(2>4'<37>A:2:&BC@1*2'!A>)5)/96;*+D=CE01(2H4G9E"79E"3$D,H52H7<'0G**<;=@#82;%;$*
@r4014
CGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACANAATATT
+
80D><*%!2>FH=.6$)&"D6C+FF56+/53.<>@,/$0#-!(=G)'BAE"=9=->4@&F7,/&/7>%4>:4@8(6:54'F**!52=8(,="76/86%&CH(+&23,C9/#$%2;EH359.G0'/&2E@%5!<&;/D?CA8#9=C,?.>D/)?B:-?2>5-+302#BB;>+%(?><;4D1H?72E%?3GF892>3F5=,(&?6,
@r4015
GCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCNCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTNATCCGCTGTNTCTGCGTCTCTTTTTCCGTGAGCGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTNCGCCGGGATATGTCAAGCCGANGCATGAAGTGAATCCGCAGATGA
+
=</91;)>7'CFBH%<B-&&D8/@D0C,-C(">FE>'C8!<H+-(02-$B9&$6E"6+A>?:.86BB/;(1$C9#F2"52>;@'E%('560408.5%A428#00!.&&5*HA("!F+'F+9=2+6.=3"AEF?!)G.C#$A<BBD3";;,,4F4B*/3CHF>4!.:C5&+,%,H8''F7)@E223+/:&8%!"$;!101<H=D$0'+B09:1-)@-:?3D="<DH1%=;"!:.57HH@9@D66D1'A-$&9D$'+)@?.+1%4"!H17C/$==;'B829F-*4DH+6)D$
@r4016
TTTCCGTTGACGAAGTTCACCGCATGCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATANCTTCCGCCATCCCCGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACC
+
B#<2H=2DE,"G?%#(*)"045GBG'==<477AF>A@5<.F:H/?<@0D3(0:$9'<G-#;1C6//)?E"#EEA+5)B0./A:(5#23EHC?-6!;C%(A%'4@=,7$H9F)56A5@!C>7%G<H;D)*G-EG'=;HB1#+&9!-;$A/(F*=*/4()5-1#A*;;>44@5G;
@r4017
CACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTNCATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCNTCAGTTCTGCGCAGCAGTGCTCACACANGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACNTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTNANCCACCGGATATCCC
+
4C>HHH&<+/@5G'GF6F'52>C("D?*/+>F%8/E6?@"!A!EB8@2C=6834*H(0ABG:64;A(&9!%#)-9@42'1C-@1%:#13052"8"/4CB=+G=B5>7(H351)'&B!G*7?4B+,?08)#>B7(080"'>%"3G7@$D:"!+D;A&#!/=1#2F#FE/?!-H1<F1A&'C&19"'4BH!881B3$G&B8>7B$H:<@@6D1@>+-/E1DD,:>)E8$E/-,:4:.*HB1!;7G,G+G0>)8A"">E@19?G((*<5AD>0!*!?".1@A
@r4018
ANNCGNGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCNACCGGAGGATTTACGG
+
"!!"()+*&&(&&**!+%!!!&&*&+**#!&$+("#&++)$#"("($'*!+'!*&#%(()'$$$('!##&$&**)$)'"$!*!+(%+!%"&!#"
@r4019
CAANCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTG
+
8DC.>G."HB.%#,>D#@=@)A<*E=9>;,,14*,A05"G'()7*1C;E?=B9%27E8;-%H846?1F:?=!A)*+F=,C,47=0;$H%55E'>)=3+/A)/(949E1+G@#/)@+:=(#:()$32=#/@;;G>")7DEE3G'9B20;/B!58>"C
@r4020
AGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATNTTGCCAG
+
-+(D;H8459!;E9+#B#:%#?39%"BBE>&1,3&+=7@E=D-1<H7B#)C>7#,+:$G*-8-7',;03@((0$9=;/,A?FA-73'476)9=$0,3)C-C!++C33:H2,:!"6+1AG-"6"2A
@r4021
CAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGNGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCNGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATA
+
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
@r4022
GCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCNTTTATTAAGCATTCCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTAC
+
5*=>:)':"4?D@HB0;"3EH?6=:<B%<%;608$?C5@@GB24118%)A;-5"B8-#E&9"'HD==,1-799/*#/)B*;!#GE:3(>B!/7,3*>45B8A<C5B0'24#/F.!./.$"BH=D1).9%+$"2>DG//D3E+3%A,5/4=)=03027
@r4023
GAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAACACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCC
+
C0D5G.<(>*8D1"%G<@4B7DD/**6BB?=@+4@DA9(>.0DE78:!!H#<%?8:*5C(5<297%??7!!*(!&.@G5%BE-EA'@/>C(!7(2)"%G'5GH,@#1@8A*!/:$AB#&A!>3=H$"&&3/;;?3B@?:@C".HC#?3.76"=5-;+C,%E+?1*?).1C@'#.3,%"FC<'+4G3A').FH;60
@r4024
TTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCNACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCT
+
-&!=A;#A.-=4;-;5%F906*8344!:!'E.5@6*G+G+F=3D4&8%%'07./(;EBH3(-#7B="E0(5@$+*#8,",8@@@H.50C(>@)CA7";C"F/!FF/7*320C7.-G+3)BD1%1-A=D"-.8*#-*+,'7A+))=E&,#41'C9%@!8@56H06">E?&7G@45@-/A?+.=1C(72B=(<?/B!.F+?%74A%CE/1+50$4@#9F9=!BC*3!0#F;H<8-8FH=$GB@@!*?EG913AB?1=!76=.4.02.%BE;!'/"
@r4025
NCAAGGAGGTCAGNCCAGATTGAAANGATGAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGG
+
$:/<.3F;$(;!A19<>;F:?!!?+D<A??C>:5%)7A!/B!0&8G@6DH,*.7(C02%17,/$%@3($
@r4026
ACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCCTTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTA
+
C!.2A&.75B6=%08-4#%1H7A9(E/)?H<:"<:1-;E9F.7?H<!D,=*%+/.B>H<08,F"2'/C*)E?9&@:D"71'2>?/H#-%:,.?1103!52(6D=75F#/)GD,28*!=&-*B(2?B(HH;F!@7*=>1,C/@:-"
@r4027
GGCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGAGTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATCAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATTACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTANTCGCGGTACGGNCAGAAAATACGTTGANGATAAAGACGGGAAAATNCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTGTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCNAATGTCTATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCNATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACCCAGCCAGAANGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAANTACTAAGGCAAAGGTNCTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTANCCAACCCACCTGGTCACGCACTGTTAAGC
+
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
@r4028
GGCAATCATTGCCGTCGTTNGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGTAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTNCATCCATTGCATCNCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATNCGGATAGTCCTGGTATTGTTCC
+
)1'0B>9C1:7C-$-F#"(>E,43AH7">=>430"99<=79E49(@6D?6D/-#$D+?-GD(H,<#H39G,#-+G.B@>44#7B$H$!4$F$#8@>*%+)&9)2(:+C;A+:H*''2$&60%2D,A3('*'*D/!+$5..#;F0.@:;-(H6G**-*A"6H6*'-8@8:$E@0/:)*"D0#86E"+HB
@r4029
AATTATTCCCGGACACTCCCGCAGAGAAGTTCCNCGTCAGGGCTGTGGACATAGNCAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGC
+
50!GH72)FFA?34/,5CG:2*""C#D3@8=AD@H@DE/'>12<.8(09AF1#B=FH"<80B-G*G3*#)-96A(8)(%1H+H)2"4':/=H2F@1>,%;9-#4(A&5-+->=$;=#8D9E;518HB>2->*5H1(610.H1$60GCF?*>A%?<%2.$11>B9,37GH%C,G9*4<$@850$3&"
@r4030
CGACCTNTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGAC
+
,$F=3<-$2$+9<F>)DH;,"9;;2H2F+3%&)<+@&C.A'?>=%'6@%"'2282760H!-3",*B&
@r4031
CCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTNCTTNCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGANGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACNGCGCATCGCTGGCATCACCNTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGT
+
,E1G?#C36.2"//;HE45.09F4>/G!C5)DE7E;*BG$:/GAB$@%H/"9D:D?:/68H&"86/HED?!6*0,#(66D'8$02#B2':%@'7-3.@@.4"&G(70@2,-21'9HH=7='<H:FHFCA'.D;H$7"D=11511:;)D+.*B-2HFC/H3:/*@0!-,"!A4.5H1F+9@3E0*;+7%3G)5B<!2#@*A3GF.0H+5B#+:%71(@A)251C*=1)$+;F4>G389&(.&/>A9C;6-4=3A%7+%((+G'A<(H!AF82&6!+18/@0=C;=62.!/)/076@)385$:FE5+BH;)9G:</B2C)?)>1=F+;3?7,$;9
@r4032
GGGTTTTCGCTATTTATGANAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATTTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTTAAGNGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGNGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATNAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGNGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAG
+
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
@r4033
AAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGAC
+
HG,F:>H(')-D-(.@0-B?D07'8:/3-3CD=+C:G,$11;465C?/-+A9='+GB@82%8<:*;<0D$=#
@r4034
CAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCCGTTAACCGCCCTATTCTCTNGTTGAATGGCAAACCGAATTCACGAGTAGAAAGCGCACTA
+
+/*<)A4%,-+.,F?2B*,)F&73$(A:E.FF=CH,G2!67F<;)6$&57<A+C?DE$(/)E$FB;88%5;9=%*)$#()'H/-("'1#<;F%*++H#D@47*B.*3%CD;&*E@C*0
@r4035
TTCACTNCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTNCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACNTTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGATGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGNGTTTACGGCTTGTTGGGCTT
+
;1>87.D;GA7A8HH*(:F<E$54-36BA/<=(1$:=@F,&D)=5B*/8;(/A61*!,E+6'97G:)*"A/H%=.'D8D/-,+!=7/6"&/GA*;3%%?7?!@!3572(72@4D3$;,&/>%0>G/'B64B1)C9C,9:5'4-'#%@=+-#3<4+"A?D.$&<!1H,D/;E&/??>17?C(<7#@G=.F:A*7(91BC>3-/(-(/A-#.B8+>27B"+%53-E*CF&7G"%9'>,13;E)3E?"8.&G/FE>H$68D,8>71!7AD.$4.+4'6=G.!:+'@#$47B)(E7-D*G"50!DE!)3.0,%*9'9=3,*3%'!>*3(=6)$%8CG:#(28'D7&$D;FE%:35/?32E8<3H7A9!&!+-F7F%(,,A=D(*?;0+;45A=@%F5GDG80766AE#').<#2D4$0EC24!@H;;'25D1$,?=/"11EG=8&F,EB.4H5'/*$#2(6,.(11*1E?<(<74!$!?/(G5C3G)>F'65<G4'6C'C61=)B:15),F-4,-HBH?D2F0(3$C3D1!6-C6++.&B>*/
@r4036
CGGGGCTGNCGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGTTTGCGTATGNTGCTCNGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACNAAAGGGTTTGAAGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAAACAGGACTNCGCGGGCATTNAAAGCCATGNGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGANGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGNAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCANCAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATANACCGAAGAGGCGCAGAAG
+
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
@r4037
CGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATTCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAANGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACACAACGATGGGTTAATGCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGNAGAGAGGTCTGCAAAATGCAATCCCGAAA
+
0<B&286/=,:@3F3436$F)*5DF4@.G>756$7742/65$0G7A,=7G2#!GDBF*2?HC?;5&!H>;$=D392%#2?1&"G+F804'>39@<=B?$08=6D97.'!#*E/2+!!$+@#H7;2)+1<2A.C8G+&=%218;;,<3/E?&;&#)&'/<#G"B9F.%G7EF67A)60#A<@58=%>(4@*&'D7H%@?9E::+*<#A:<!:7.0$/#+;9,-).6B5*/<?.00A@06;*8;:H48+1<<;=""&5;"&D+G>H5>16&B*)-H'#&?%H&7@-5F>G85HC6,#->$;$:5#4'@8F5?&*#2
@r4038
GGGTTTATAAGGGGAGCGGTGACCCTTACGCGNATCCGCTTTCAGNCGTTGACTGGTCGCGTCTGGCAAAAGTTAATGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGCACTGCGACCGGGCAGGGGCAGNAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGACGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGNCGAACGAAGTGATCACCCGCACGGTNAAAGTCACCAATGTGGGCCGTCCGTCGATGGCAGAAGATCGCAGCACGGT
+
E"63B.F:!'2@?D"'#&1E=?+'8G.A#8+7)B18D"%;&-3AHD>!!#!49G,%E5:?D97,69)-81%#@:.$@A9(08!-9?/)8:.(%*+7D3:4G</<)E$@H-H781'<.1)03>8:5B$(8**C<;&+-6.%F&8%G-,:AD>#"C)>6>%5+#.#0)2'17*"6D0B+**'E@+1"43BC<5'%HF3+@&))"&(F>'A7H$D<:H!*A>-')45)A490.4*"9<3?F+"5F36/9+*$5&6(%5(-#=A..=9552=#+D9';%8#>$*:*:5/&-B/$.,0$%9/82*>%92H5<H/>39'/3-9:4%;3@('(&97H@0??739G?F2"E6/5BH65B'@+A5A.$,"=/GA%73A!!=#7A@#4!4*E(D!C&A:(>6%B===:++B186->!&.AAEF2%#>8H8,
@r4039
TGTGCTCGATGCCATCAGNGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGNACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATAACCNGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGNAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTNTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGNAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATNCGAATGCGCAGGATGACGCCGGANAGCACCACAGACCAGCTGCAGAACAAAANGCTCTGGTCGTCATACACTGAAATCCTCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGNATTCTGNAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCG
+
("*$!+((*&+$%++&*)*#+)$%($$($**)&'(&##()+!+!'*(*'#%'(&'"+("+!"'%(*%"(++#*++$%&$)#!$&+'+!&((&((+(#&)*"$%%&"$"*#!!!!!##'&%$'**"%#+"!#'&'+"("*+%'+'%$$##%&("&+%"+)'!!&"#+"($&()'#('+'(*%*%"'%#&)$##*!)%%!)$**'!!!"%+#%*!$'$%**&')+)+'($*#!'"$+$(#$$)"'"&!%+%+')*'%!##&'('"+*$$'(#*&%)"$$'"!$*#%*+&%%#++($)*!&)'*%(#&"#+$($*!('"%&$+"&'#$)+#+!!*%+$*+#)'$&'&$'&)$+$#$)%!#(!#')$!&")'+#(%(#%*$'#***+%$'""+%*+)&!+(!'$&%""(!(&''*%('"#&(&(*"&))+$&)+!#$"!*'"((&+#%!#("&!)++##'"##!+$"##*%&#$"&*$""+)+**'+('"'(')!')+)%#%'+#&*!%)''!#&(#*"&"%#%('+($&(!'")+$"!%"**'#(%*()#'&((')%&+#&"#+(+%)*$"'(#"!##)"++$%*$)""&%#"#%&+""(%+&"#(*$*#'$#!''###*"+$!!"%&#"((+)!#&&(&(#*&&$'*!($+&!'%)"#++"(!!)+$(!*+%&"+"$'!'&$%##*)#$+$"&**#$*+"
@r4040
CAAAAGATGAGGCCGGAGATATTTTNACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTNAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAACGGCAGGTGGGCAAAGTTAAGGATTAATNATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACNTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCNTATGCAGGAACCANGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAG
+
5#-+A#<826;$!0.'(<1@6()8F+)"89>#D(4&H$6'/9B4)6DA4"H0--@--&9<+4/+5&4,"$+#$0$B'HAD=6+:75>+?C:E><;B#F:G6:D3'*."7,H/.1H?3%>A<<)5:8-D%@30,:%.<4:B8'B.!3C0"3#1F4:%D@C-C'2<(C&>3&@*!C-$).*B!2B46%?2:/0;"5369G*-G19";*?E%<H"3".57"=:;"558A==F2%+?-;D)+8%95C>=,/!9+9B6D,:5E!F39"/9#>33E)3?.;3GF7B+'%6.F:<0A9"21$9H8F+GA1(GF(9(;#$+BC1!57;,99(3G6=5A(8G(*(G4?.G"=4=/=G0-GE#.>4%$D+3G?A!.'C51>:.!E2@6E2!)(!';<@!BBE/BE+6??&
@r4041
TAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAA
+
98F4%;3:;%=05!:98B-,3@E>&8=.47@?G0@.E+54#&CD0F<4G;033;81-#<H1-<9?A'&C;-F-''(3H=C4*,:G!+%9</4=/-.<@0*&:5;&
@r4042
TACGCCCAGATGAGCTACTCCACGGCATGGGCNAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTNTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGATGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGNAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATANGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCGAGCAGGTCCGTGNAACGATGGAGCNCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGGTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCNCTGNTGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTACGGCGACAGCCTGACTGCCCAGGAGCCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCA
+
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
@r4043
TNGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCNTTCCATTCNCCTGTGACTCGGAAGTGCATTTATCATGTCCATAANACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTNCAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATTATAATTTTGCATGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATNCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTNGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAANCAGTAAGATAATACTCAACCCGATGTTTGAGTACGGGCATCATCTGACACTACAGACTNTGGCATCGCTGTGAAGACGATGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAA
+
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
@r4044
GTGNGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAAGCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGNTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTAGTTTTTGNAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGCTCGTGAGGCAAAGAAAACCCGGCGCTGAGGCNGGGTTANTCTTGTTCTCTGGTCAAATTATATNGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTNTCATGTAGCCGCTTATGCTGGAAAGAAGCCATAACCCGCAGAAAAACAAAGCTCCAAGCN
+
"&)+%)($#*()'%'#%)+&**(!()$##&'(+$++)#*!!+!"+(&%+((&$+*$'*%(+(*')&"%'"!*#"*'%$&)!()$"%!+)$++(&*&)*&#&&%!%%)&#*#'!)+$$$(+)+&+&'#&()'!&(#%*('%'&#%)$*&"%)'*))!''$&!"$"!'&%+++#$*%('(%*"&"!#"(#)#"(*#%(&+%#"+!"+!$)#(%&'("'!+%"'+*)#!%&"(($&("($*&+&!"*%%)*!+)((##)')+!!*)$&#)&"'&"!%(!#*#"+)#)&)&*)+%)!$)"&"'*!+#!*("*!*#"&%%#'&#+"'!)!$'+)!%!'!"*+)**&(!%&")*(**""#%"&*&$$*%'&('&"(('!'*'#+&&+"*((%+"(##&)*$&)%($)#"#!*#*('")$"+#*$((!+&+$'"(%&(&#$&)"%"$+"&+%*'##+'(&*)'($%&&+$#!+(+'!&"')*'&"'!!&"$)#"'*#+%"*(+*!+!)&('$%!!*"$!&($))+&')&'($+%$(&"%+())#'+%((&(""%&)*'"*%*)'+**)$&(%)!(("#!))"*&"$"+&)+'&!"!#%%&&*")&$#!*#!%%*'"$*&%!*#%"*!*
@r4045
CGGTGACGCCAGANGGAGTGTNTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGNTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTTATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCANCACGGCAAATCACTCTTCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCA
+
%0$E-+#<3HAG&$06='?/-E01HD.DB9+9'?70-(%0/+#!+9+D+-F&*'A&!F@0+(G<E=(0@7*H*87H1"-A-(,H*'<?&B0%:E/A?*4D39&-G6=<6-B>;G6"4G">8H,F)#5#BHH&<E3=F?,?H3$G!B4D@(.>=H3764.7FH(47@4=$6CG+1=+@AD21CF%7*4)F57/?-&:*4<'=(8#D>F(6!8=DE"23%D$0?'=E24E11G::6=&D>D/!6EAC.'H2G<),,<-"7#!4HBF#&="3%<@E#$2BG.3->0!9#(C;5@<3;-%H:G+,G3D;9/D%<93@&-0!<>:+D,D678;/G#/H32<,4=97?--/C/7*'?3#/@!<+;G03F,(">7;$2";$;8E$E,4/G3H;>0='1%!#$7?E1,!D5#,B*H-G6E)%C.109G2G#H2*&1>+G>,87G<"7!@92<:*,8E74/*E?5;!,4+D*7*#8<1/>@"!E&F,%$$-GC="5/(FGA.-F
@r4046
NCAGGGAGTAAGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACA
+
!'&!($*"(+(&'&#+)("&'($%"$#!(&'#()"%%$*&*#+%)(#&%%)##((*(!%$'!"('#%&&&(+"++($'!!#*(&!")$$#
@r4047
CTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCNCTGAGCACATCCCACGCGTTACGCTGTGTGGTCAGGTANGCANTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGNCCGATGACATACAGCGCCCATTTTTCCACATCCGCCGNACCNANANGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAANGTTCCNTCCCAGATACCNCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGNTAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCNTGTTCGGGTAGCANTGTTNCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCNATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCNCCGTTACGTTGTATCTGAACCAGCAGGCGGACNTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCNTACCCGGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGNAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCANCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCAGACTCAGCAGCTGCGTGGACTTCANGTTG
+
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
@r4048
NGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATT
+
#;?0(HC9$$1!-D<((%&3);;3.-$&4C:>+EE$1'94$!+*A.:==9(9@+$&F(2*-9B%1H$G:?<F-G+A!21<92.#)>7&9+&04&<+$/AE$';3)5<7*'3.&3G/5%:02!G)%:0;B"A'9)A0E(7.7/33=,,=%2#,=-'H&E-'6A"+&>A;?"A5GGH
@r4049
CCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATNGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCTCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTTAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGANATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAG
+
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
@r4050
GTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGNCAGGACAACGTATTCGATGTGTTATCTGAAAGTA
+
=H'1%G)G=H"G(3&0E-./*A6AHEA6@5&@,3%E36.2-61)>$508//&AG0,!86#H9"/E2"/&;7.4E3#9'H0@G39G0;8E-&:.@5)@6)HC)A?)3$+2(>8"*4DD&,@+135>3ECA80CF01,H!&,5,6FE-);!#+A#"%-:
@r4051
NNNACANNNCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTNTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGNTTGGCTCCAATTATTTGTATANTCATAAAATCGATGGAAAAACTTTTCTCTNTACCAAAACAACTGACAAGAGTCTGNTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGANAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATACAGTCATTAAGCCAAAATTTAAAAGGGNTATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCAACTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGNATTAATTATCAGGAGTCATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGNTATATGACATCGGTAGTTATT
+
&!%*$%"!+$%+""'&$%$*#%%'$!*%+##%*)')&'+%$%)*"&!(*'(!$)!))(%#!""'%(&(+)*'$$*#%"$#$*'&"!#*&*#)!!'&$#!*'!'(&$'"*+*)!%"$!")$+'*(#*''+(**+)')(*!*(("*##&*!&#!)(#(%$%#*"*+$$+("'%%&)%%#%&&*#(&##&)&*)$&+!"$$('!'(%"&*"$'#!$($%'*)'+&#++"'&$%(($*&&'$'(###!"*!+*)#+!%$"$#(&*!('('+*&%%"&$&"*)*!%&(''"*"#)+#$'&$(#(*$&+#%$*(&($+)$&&'*&&&*"+""%)$)!!#))$%%%***!*)#'*&%$+&"&$'!%$$!!##"#'+(**%!(%*&&"+(!!#*$$$('#%)(#'%)!&&)&(%(!%&#*$&"%&$#$!%((")(")%))%($%)*!%#)%&+%!**+*""*+*&""!%)!)%'&'('((+%)(+!%$'&)%&"%#(!+$)&#$!"+&(%%(!*$*'(&*)$&$!"$(+&'#$#&)'!%'*#"&*%!*!(%&"('&(''+'&'%&)'(##''!'%!%")!*&(##!#)!%('#*&'%'!)("$(&*+)!+#&%"*$"$(*&+"&%+((()+$&%""$$+!$(!$)'+#%%#)'#$%'%#*++*$!)#)(%"!)#!!*#"%*!+!''$'+'+*+++')"((**%)')*)(+(+'+(&+!'"#%+%#"(*%!&&)"%&'+'%'$%&&%#)%&(*+(#+$!&!)&$%!"%%+$%(''*#%"'($#+'%!$%!(&%"("#*+((&#*(+#+*&)$%!%)$"!)$#&&#%)!&%&"&&#*(%"$'"+#&++"+*#$++'!($(&$'(#(+(+"$(!)&!'%)(%%("((&$&!)&*$!'#'%%"!&&)"')%(++(!)!%#$!('$!%&$')*"!#++)$"$$"#$&#!''+""*("&)+&#%&"'*'$*$'+&!(!((($%)#'+)%"$)!)+!"&&)*'!()(&#%%$*""$'$(!#+!)+&+#&)$$'#)%"$*$%)$&$)(*)!%*#'+*#!%"(('%$%))&&*&*(((*&)$&("#(+*&)(!'#&$$""+!*!$*&%+)&%!*$*(+$('()%*&&%$&('!#!(("#'*'#"+'"*+%%!+&#&!()'$(""%%!%
@r4052
ATAACNNNCAGCNCGCTAAAGTNTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGATCTGGTCACGGTTAGCCAGGCTCGCCGGTAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGNGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATC
+
)(*$"&$#'"'$#&''&!(#$)$+(!%)#%)(!&+!!)&((%%'*")!%+!!+(#%+"!!&!%$%*)+!%)!+""%$+(#"%('+%!(%'%'!#)&!'%!"##$&$&&!$$*"!#%&')&)&'+)%*!%(+''%$!%*%)"&")$'&')%##&*#+'#&&#!'!%##*""#"')%!#)!%)+"!)$*"(%$$)%!"%*('!"("&+'*("#()+)&"#!)$*$)&+'#!&"#)")$#'#()+#)&(&(%"*&)+$%)"*$)!)'++&!#%)'&)+$%!#&%!(+#))!%*(%&$"%'#''(((&+")$&$&*#*)%&!%(%&'!$%#$'))$$+&%&#+(*+
@r4053
AGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACNGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGNAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGTTGAGTGCCNCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCTCCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGGTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAANCACGCCGGAGGGGGAAAGATATTTCNCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAANTGCAGGGTGAGATTGTGGCGCAGGTCC
+
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
@r4054
CCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGT
+
4&?'?5G4F2&?6!&6045%:5=1$!C;)*"B"D0*;!*CB9-B+60<9&E/>$-G(9C4.4,#-7:0H**>/4!#=.)/3';$"?D/-E2B>$5:9+7B3H'DHDF@3D;D-<:=#@-/'AB('3
@r4055
CACGCTCTGTACCGAATGCCTGTATAAGCNCTAATACCTCCGCAAATTCGCCTACACGCATCCTGCTGGNTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCNAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGGTTGGTTTGGTTGGGTCTGGGATTTGCTTTNCTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCNCCCAAATAAAAAGGCCTGCGACTACCAGCAGGC
+
('+!"'%!+*)$+(!'&$#"*!#()#%+&*##++$)++%&$"!""#(&*!!+)++$!!$)$*#"!'))#!$'()++('$++*#$%'""&!')!!"*#*+#"$$'!"&#&'!"+*+%*(+&%!!#!!&)()&+!(*!!+)$)%!#**&#&$&*($&$+$'**'###(*#*#&)$$(#('$%"#!'!#$%')+)'!"%")*$'#*'#))++*#(('!%(!&(#!%$"&%"#"*$#!&'$##+)#''"$#*""%!'**'*'()*%&#%*#*+($(!&"''+!(&+*%+!*)$&"%+(#%)")+&&(()*#*"'$$$%+(')!'$)&$%&%'('+!"!"$+$($''#*'*)!&(+'+(+""+&'%&"%"#*'%+(!!)()$!+)##!&!*&%(!!)(#&))##**)*)($&$#()'!
@r4056
ACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGNTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGNATTAACATTCCGTCNGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTANCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTNTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAANATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGC
+
G-+','C48A2C8C7?,001CF83"A<??8$+;(8A9+""'@G1/#.*F<>+</<%'D8#5?B7A:>+=F(5.!>/%@2:C(9:62D@H<,3@"G,%C8)8C2#1;8$)E(5/4)&*A-)+),:)&)GGB89G#339)3*;#!$7'/5ED?A(CC:2!+5(=;8HGAC2A7)72A0:*>:F:)/!0@C*C2'#B:@%@;G8358FHD-!=!<.6H51B%13%"786/.4872)!%<C1!27CB8?!'553DA1$*E#4;$5<9:3EG(-:%#A:C:&=<<58"C*A;0?@94;6?37CFG%"#<-B8*<6A*AF*'@/23&@F?E/,<##,=="FD:-&$>.$@$2>9&/H=E24:%>9/=8<#$:59@!F+F0>'6804!'*3D6G0E/+<4*H-*.0;/#-?&:<",46==F;B3/D<H;!D%.:=H;!$C8#$:9<?B)!8B<;9E+20314<$/*.755)@?>(2'5DA#,;:H?<5<C,>.6==03
@r4057
AGCAAGCCNGGCGAACGCGGCATAACNTGCAGTGGACGCCAGAAAANTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCNTAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCANATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATANCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCNGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTNGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGNATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATANCATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATCTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATTTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAATTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGNAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAAT
+
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
@r4058
ANAATNAANNCAGCATACTGGNGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGNAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGNATCGCCGATGTTTGNTGCGCAGGGCNACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGNCCCCCACCATTACCAGCGGCGGCAATCCTCCTGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGACTGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACG
+
)!$)$$&$$"(*+$$%%"*&(#)())$$##'!!$%#*!!#**'(+%)&$$"!)&!*%%#($!!*+#$'""')%+*)*+'#+))&&!""##!)!&$"$!***#)+&!#$+#*$#+*#!%(#)%$)"&(!%)!)#&%"*%(#%!"#&$#%$)$%"#*#+")&#*)%#*''#)"!$+!!*&*+%$#%$&&*"%"'"#+"%+%!*##'"#'+"(*+#+*)+&)$'#"$()#!##')&$#)&)&$&&(*+#+'&'%"#('!)'&*)""+%'!$'$!+*!#$*()'!+((#%+!)$(+!$%*)&')"*!(($#!*&&""'((&**%)"*#%(")(#"#)($%+*&%!+'$#+#!(+(!*#*#*!#!%+(##%"$%&+)%")"+&%%"#)%&)*&'++'%%"!*%')&'$'*(&)!*!"($&*'+!&%$)+(($!"$%!+)##)"+!"
@r4059
GAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGGGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGC
+
9)F(!+;*3+$@F-6AAF-7:::+7:@D3D/"=$.+)#1&-">#5!AF00,F9!,C%.)%"!".F7;=;28:4,33B4-4-/=&7.8E,*%.5:2?82$C/E)=G).!7(&69',,'E<H7*!'EF'5:(!=H?'!"?2$09G)D!&50@6H<%".78.32=%6*FD77G;$G;4D'(1:F-A>G<30B:/%&%<EA?+-.+;#""*GG(!1+&%/A,0;!6<:!3A%*#A:/$B*H'>*-633@3E,@AC0(A>5B5/B'D#<%2+D3A"#(0$?"7D'8>$,5&C,"6H7;@($H>A?B29=A=(!8A=&6%).$@<@;!%"G?B*9<((.'9@+992(?*/**&
@r4060
NGCGGTCCTGCTGGCATTCTGGAGGGAAATACGACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTTAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATNGCA
+
!'D3A,1<>5">>2H59"A-!8$=D=5C4<020#!GC$E%6>H""A,.84;,0.*:HD?%%'7!7.$2'@-?@E+5<!3=*5&="@*);FF"56&D91!6G4#A:$7EG)8*@@."":#5;60(;?%8B(3AF,E9)<,"EB&<,,63.5.('H@!1,-$.$EA-*<-2D::!E&)A>8G2@5>-C%-F<4582B6($AB;>;0@'
@r4061
TAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTNGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCNGTAGCACCAAAGGNAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGTAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGANAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGANGCGCGTGTGTATNGCTCACAATAATTGCATGAGTTGCCCATCGATATNGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGNTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCANT
+
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
@r4062
ATGNTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAANAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGTCGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATT
+
17DC7%.3>(=7+)":!0F7B0?(4;.8&+$&H.5>8C2B34!%(<',5@@4'%&3A+)F&!FHE7.B!#1"'$(F8:<C&77EB/(7!0AH?&17?D=&*%+@/EC:>.&?$37<*E3$>?1%119<%5"B?>%E5"+.D/C>&3H(+F>)<8",!FF4"3FCB:97$=>;-(0.D:=+@D:#?)!60B/6*!$?0:&#*BG@<F4&4=A1F7!*;BA/%*</52!F$E4!$?(4H?#/-@,&3$097)&=*&D*D%15"<&H32/$=6:&0G6**%#H6;D!2B")H29%/&(55F%8:E7-*D,5B=G7"F24)&>7,5)341?;;.87CCEE"/$+E<<BD0'A+""6/5,'0."E4>/14;)DA!$,";G1:&BG#,6.&>
@r4063
TTAAAACAGATCTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTG
+
,=94(:.';?0$F%+64'0-B"13.$'E7CA+!3&H8()=C68>1"39-HG=59$;36;.2F1DA'E3?>*C3=<.A&@=/B@FG/<!&<;0!?<)>.,!E/$.$452'D3.2").@H#8D=0F<B.F&
@r4064
CCAGGCCGCGCTCTGTCAATTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCGCGACCGTGACCAGTTCAGACGTNTCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCT
+
.(:CE:=A%B)0G%(+3E//43G!!:+*!=&'G9($#=G4F3BH>D+H?B0(9(7B)@#B05<=%--6>1,;6?>FH&5)='0E5(2E@.D#=*>86D"H70'81A@A>HD93G,+%C>7'1.'616=31#E,)G:'"+#E(A%<;C+*,DGCC/4@)9$85<80HF8H-5G<GG2GCC#</#F8(/*-$=A6'#/79BH*,&2GHG0DC5'.@+B/&7D1F3;&E+4='CC9A"#1
@r4065
GGNGNTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACAGGCCGCCGCGAACGTCGCGCAGNCAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAAACGCCCTATTCTCTCGCTGAATCGCAAACCGAAANCACGAGTAGANAGCNCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGNCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATAGTGGCCTTGGCTTTATCTCAATATTATATGGATGATAGCTGGCAACTGATTCAGTCCAGTAAATATCCTCNANAGGGAATAATATATGCTTT
+
&*"('$+)"#%*$%$+*$!+"!'%+()$#%#%'+($**'%!(#!##(+'&"'($$&#+'##'!!&+"+'"$'%"#+*!%($)&#*+)'%$#(*'%+*+!+)+&$!%))"!#()(&)"*%+#$&#%$#&*%+!"#*(+#*$"*))&*(%&(&!&"&+("!""##'#+'#('*$&(""*+("(!&&%&)"*)'!)!)((!(!&##"'%'"('$+'%+))%%"(+$!)!$"&*+$'%&&$'!+##&(''%'("+%%%**#'&&$'&$#!(#!!'%)+#$#('"+%('()+)'#%")#$*#%+%%('$(!&*($)#''+%+"(!'""!+%!&(&!'($+'(#(&+)*')')*++%'##'+&"&)*)%+&("#+&&!!'%!($(*%)")&)"(&)!*#!(!**#$!&%#)"+)!#*&!+%)$'*"("&!%'$"'&+#'(#$$&+%*$#)*#))&'#+&+&$)%+#*#*'+)#(("('%#++&'*"+"&%)*(++#$
@r4066
CAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGANGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCGGCACTG
+
F)6>!8=E0?,?&A14#?7*+3G)$'H?-!9C#<G70G%H#+*H'H!&'+';B%>+'"+(>B0>3:,D0>2.HA93#86?=0=6E86:4,F#$'B:2;<5F39<#B:H7?2*?/F/C/GAC085A9$>!=)>$4F,H#$@&-DC4=1'2(@6>=/)D10+%*:B";73+$<!?!##H1G"$'GEHF44E3$&FB45)+/"F57A:0529".)<
@r4067
GTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATT
+
E1->>&%=:H.:D0'-1&D++),<4072D%H",.*/H-;4*5HHA$>1B=><-.503?2B-96B..H!E>=,:4/1:"18=@,1#=3/';0EH1B58G:'59;;%@E!=,'("0+F3/>=#(1=C!?GC,*1$9?/#'2F0$9@+1
@r4068
AGTANTTGAGTTGCAGTTTTACCACTTTCCTGACAGTCACAGA
+
'D;9#&0"'-?CGD->'F6*<0?&D<3AGE2>C69@BD/.>%4
@r4069
AATATCTCCGGCCTCATNTTTTGCCCGCAGGCTAATGTCNGAAAATTGAGGTGACGGGTTAA
+
ACDC@AAGD8-?7<'B4(<:(@?-:$@H6.<<.B7,-&&G,0!G**>5'-4(/'>-EG(@8D
@r4070
GCTCTCTTCCCACTCACTCCAGCCNGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGNTCTGACATGACGATATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTNTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCACATCAATGGCGNCCCGTTTTGCCCGTTGCTGCTGTNCGAATTTATCCGCCTGCTGCGCCNGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGNCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCNGCTTCNTCCAGTACCGCGAANTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTGATTTGCTCCGGCATGCT
+
0:-G,#)0-(AD2*8(:>$8"*+!;*,9@&DE+7/!%32E:?;DG?$&05,8!09.)+/+F6BA'1D+&8'#C+4+,A22E@#H7>@>H*C!G:0H.AG#;B/<?.<:/5!#BHA9==('1;:0");F>."31*"@.%FH0.7>@6&3*)1#';.044=)D,<=9<2;84'8&,BA/0:F&-2.+3*;#:'DF25?$C*12H<08@-),7))3H=%A&(E@$"3H'@&@%G5'18>H?)C"+'6>D'5,C.70?.6/$5)))-4<%/CD=>&AG(D22G'!><5,;A;#/&F+EAC8G.2G:4BA)'.3@#?9:@-(</$12<4(+.#DF?D>!(+!.7D4#G47$'*"<F:>16A?)F<459!G@59,>BG,9<,5B=DH<?3)G6G816=76E'G3+;A-06H4.GC9E?03*"H<#';9"H7#A=9@::#*8=)HB2':(&?-$D"*HG$+&BF3.'5HD5C$-F+(
@r4071
GGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAAGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACA
+
3C#;!:9@3'$@20G4$BEA(2D##B%00!.CA#%)$138,46DH7!1#"=.&>.<627;9G=E/6,>"&:DG$C4;-H"6@;=7(<<A=3A$6$/3
@r4072
CGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGACTGCTGANCCCAAGCTNGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGNGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCNCCT
+
B4C</$C$)G#1BBHH."4+3D;(5#C%'.*=/9@(>$+#7;7;BH":#!%;$++8?7@C.#!'2.=A!'42A5$A$=HH<49B6$4C($*,G'(.=)>%3"22@0)$A//$4B4DH<00B74?&#@"30(!@C!$!<'@.;.%)==5&<):A/?:BC#61F42<8F:-E/9&D).4(&5DH06E4:DF9.406,4";8-:-*#*'H>?;+'D-6*2'#D1
@r4073
NCNTNGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGNCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGNCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTCTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAANGGCCAGAATCTCTAACTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTCCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGATGCACCATATTCCTGAACAACTGAGCAAACNAGAGAGGTACACCGACAAATGGCAGCGACGCACACANTCCCTNTGGCGNCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGNGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGC
+
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
@r4074
CTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCC
+
/+71-7-.6CD6;/3/+-#+49=$<(H*,<5%,8:@7),1197A*A/(%$&,8%?8>&C'0&72E'A7*%;/+@-$0,F1H3&!$?-!#%3<H3&8
@r4075
AATCTGCCGGAGATACCAGCTTCNCGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGNGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTNGCTGGGTAAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGAT
+
=/3;6GG$6+#E27+41%;<F%H&GD*(4!DD:-A613F*A*0");<7#10"+:8$G20<1'>&9D81G51<?5?.?,'A5F#*H5E&F/C>@AHA9C<8+"%'%>=))$17B4-B&0%4.3,:3')047B18<F'$>E!-@,CC#GB)A-G2:&C":=%?C;5H*603)7)=E6/?"*+D4C7(FHG-5%>@(-4#29/.1E/=H"%+@&0B3@5"3H*'EC=*-4"'A81##B51!!
@r4076
CGGCCCATAATAATCTGCCGGTCAATCAGCCAGCNTTCCTCACCCGGCNCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGCCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGA
+
'//)'2BD&.H"G->288+HB$1D2(2&5'H/(;C=;?;#-<#7!0>??=40;.1?@,0&1:2>0'4?$G.,>#19?27!+C=+3,1#=#7%!=8C?=E%BC;"=5.(0#15,#"06,'1G:A*6G9%.G-?4;E;2(F0+,&%>"60046?1!54"*CG/)>HDADF9G7E!--9F?.,7D0/=&!#0>";DA9.?E=0;.F9=E10$)BC#G.@G'/8%617)3+<(3%56ED.,+.>@G,BA(3).=+.48A$4G*3*%*=4G;D/EF0H>1;H1:732:*&B71.#<6C4B++6?!&C=D'$31)F<EG0,@,,4"8@F9B2.D!E79>F=FH!+H63-@CE$#4!7;G:5%<!$/)--'4*=8"1>64
@r4077
TACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATNTATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACT
+
A?-#-!)C1'+=A973',F96%>"A"1FEE53-C&+G1'ED)094'G'(:2H=A@!AD*&$?-&4<"4=@&56-?!-"3!9)E,7+5(<'0/;%(2A='46!5BEC>0,!2.D3G@9$-6&>%(.9@&4BG'(H:--.'!*7$>-A;8E;74?7(>"B:*A<5,)EA>;?=A3(*";4=@@&(*53%9:-<35"800$(C+010)1F/(1.%'GC-*6"0=<G&%05*37@,B@5"*C;%>B469G.-E1)":C<0.==7G6@E/&%A$!0
@r4078
AGGCAAAGGTACNGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCA
+
<"=&AF,A+?EC:2FA7:G9>/:?353".(FE/*.3E+D,*/F.&7-);E*)@D:C3%):-4@:")&(H4-0(!/89D&=E*0F,5>A<F#
@r4079
AAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAANACGATTACTCCATAACNGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACGCGGTTCAGTAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATCTTCTGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCNCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGNTGCCACGATGCCTCATCACTG
+
+2B);>#DDH7@69&@!=AH(8-3"(8:.'6">B@:+%825?6)=E.8BH*/2/(C2C>1>#;8%!8A!-0#.)!3E2$C"(D:'*C>"86'75@/6E@B1=6".G*7@/#*2H7=B<0(86A<+1:CB*/??/G07C+(B/*,(3!"90&+:+DD9<1:A?$?2*0CHF)H=A98!3&E,4)-%:$%@07E$/,=.%C!./D/DA,BG'.6,+3@?9E5G872-!-F?3#>!/"2A,!:"B*+;8"C2:-@?#H,C4*(3)3G%E*5%%!2,/3="<:$-?:7#;<#"B,;A.1=896A?'6*F(FF=#F':/70@7*&9@7=;+;0-/1:#22*CG".:3$>@A@2H"3$!H/("4)35H;>3*7.&6/!7!*&:0>3C-((<BG6,50)EA:(1&(?DD11G0%,(/FD)C%+*2E86++"-+.2!+/-/*C<1.:6=22D<8H5@'>)/D/@"'CG8+'>"H<20%78H#E78CA;E#(4:?<;8
@r4080
CAGTCATCCTCGGCAAACTCTNTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGNCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAANACCCGACGATATGATNCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTACCACGGGTAAAGTTGNGCAACAGGGCTGCATCC
+
@/65H6F>H2$HCF:G&.!H:6+'-B?+-3//3;/2!!='62C5'/.%9$F3.-.9HEG8-<E-G9()&.@5;;%D)>H@G#8@*>9.+8G-767=>'?4#%-8"(1#*<G:0190B#9@0#@=,)B(E9)E%2-<,%5=7/1.E78,;,&25$.7&2,1!E9:C)-!-'<6:C==)8H:@-8'*@#H*:2C*3C>!6(CAC&.?1/$C1%-<5>=<)$+.;5E88&/#-.>/;
@r4081
CTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATC
+
H(%C5H./F$CG=!C54.>36/*>EF+)D5.3'H-A,236-$)$B:F?E=9>(C71=#%(47"<8$?:66-?,890&-AE7
@r4082
ACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCNGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCAAGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTTATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGACACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGNGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTNGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAA
+
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
@r4083
ACATNANNTNGGTNTNNCNNNCCCCTNNNNNNNTGNTNNNTNGNGCTCCTTATNAGTNTTTCNNNANNNAACNNTNGGTANNATGGNANGCNTNANGANCGCNNNANAATGNNNTNNTTNNNTNGNNCCCNNNTNNTCTGNGATGNGNNNNGGNNGNNCNGGGTNAATGNNNCNNTGNNNNCNNTNNAGNATGANNNTNNNNNTANCTGNGCNGGNTGTCCNNTNNNNNNACANTNTATNNNANTANANNTNTTANNGNNACNNNNNANAANNGTGTTTNTCNGNGCTCGNGNNNCGNTNAGATATNTAGANGNCATGATNNGNNCAANGTGAANNNNANNATNNCNNTNGGTNNNNNCCTGNTNCNNGCNAGNNCCTTNATNCNNNNCANTANNANCNCNNNANGTNTTNNNATANNCANCNCACGCNATNNTTGCNANNAGNCNNNNTNNAGNNTAGGGTNTACCNNNNNGGACANNNNATNACNANATNAGGNCNNNANAGGGNGACNNNNGNNNNNTNCTGNAANNNNTNNGNNAATCANANNANANNNTANNNNGNNNNNNNCCNGAANNGNNNANAANNCANANGNNGANGCGNAATNCAGNCNCNNGTNNTNNGNTNGANNTNCTNCANGCNNTNAATGGNNTNAANGNCNCNTNTCTGNCNANCATTCNANNAGNNNANGNGNAGGANNNTNNGCCGNNNNGNNNCNNAGANTGCTNNGACANTAGTNCATAGGTNGNNATGTNGNNGNAANTNGNNNNN
+
$""#!#"$$!$"#!!""#!"""$""#!"!!$!!$"!$"!#"!$!!!"!#"##$"$####"####!$$#$#$$#$"$$#""""#$!#"$#""!$##!#!##"!#!!"#$"!"""$#!$#"##$$$""!!!!!!#"""!!$$!$!#"$!""#!$!!"#$$$#""#!"$!#!!""$$"$"!"##""!$!#!$!!""!$!!!#"!""$"!$"#!$$#$#$$$$$#""!#$"$!"#!$!$"#$""$""$#$#$"!$$"$"#$$!"!#!##"$$##""$"##"#"$"$"#!""###!#"!!#$!"#$""$"$#"####$$#$""#$$$""!!#$"#!#!"!!$#!$"$"!"!!$"##$$$#!"!!"$$###"!"!##$!!$#""#!"$!$!$!!!$#!"!""#$#"!#!$$$$"#$""###"$"$$!$"$$!$$!#"##"!$#$###$"!#!###!!!!!"!$##"!$$"$#""!"!##""$$!!"##!""!!"$!#!$$!!!"$!"#$"#$""!!#""!!"$$!"!!$#!###$"!#$!$"!"#"""$!$!"!$$!#$##"!!""#!!"!!"#!#$$$#$"$!#"$##""!$!$###"$$#$####"!#"#$#$#"""$#$$$!"###!!"!!!##$!$#"!#$!$!###$$"#!!##!$#$###$#$$$"!"$#$"#"$"!#$"##"$!!$$""!$""!$$!#$#"$$!!$$#!"!!#"#$$#!$#$$!!#$#"#!""$""#$#$###!##$#"$"##!$#!##$$"#$$$!
@r4084
CGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTC
+
6BE%7>8-(51>/!$.'+2(2!>%5F2"7#A34!?$:7#-(#H"/:$D&*0),<B4D>9*8!"-E*F747#GA"@05EH3=+44#&E70D6$:!#:'4,<8)8D*5!)
@r4085
GCCATTGCGGCGGCACCAGGCNCCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCNTCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTGTGGCCAGGCCGGGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCAACCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTT
+
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
@r4086
GCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACAGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTG
+
8@A5'3)*)$;0C>9%@D,98-3<;+A.69<@FF-1%)"B-1/)9#//3=&3;.1<>)35"G;B.20)%4@:>3%F(?:B!)"00(3E,"?A:'4#CHA<9+E1<())=-;2'+$:.,%E8:2<.-E1G"0"9!,!36,FD3@D(-$46C@7!<$$'*;(D23<
@r4087
NAGCGGAAAAAAGNGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCNGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGNCANAAACGTCCGAGACGAATGCCAGGTCATCNGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGNGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGGACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTAGGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGA
+
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
@r4088
GCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCNATCACCGCAAGGGATNAATATCTAACACCGTCCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTNTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCG
+
A!D#4A<!=F63,!$!648$>EG5=C&@7-E;?1&%0HC4-(.C&/=DCG:'$+?:;FA%8H%>5%>01"GA"5/4-1(<D0"!323E(6D<A$;6$?H6!,03F".$&*0:(4#%@&!E05>*!HE;;16%)7.@0?59/E+($B%>8F.04<?=151F%/2?F:7,;0$75,EE.B?=E2<.E"19@+6747@4@##7%E8),;-#F50F?9/&?@?*@#@0<B,?!4%9C+$D60B3+12*$(7E<8B+07)7B<0)GE":"50+9401*1#,0!A!#E/68"@6C!1<;50'D$G<(E.:$6+<A25C854/'1=.D1(?
@r4089
CNGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTGAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACAGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTNCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGANGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTAGCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAANCGTTTTGTGATATGCCGCAGANANGTTGTATGAAANAACNT
+
)!''+'*(!+%"$''!!"+#'!'&*&"$'&(*&!%%(+($#%!#&!!($$'%#')&'*%++#(+**#$#&)!)&%*&'#+)!*&!"*#"(%&$$%#"(!!'(&')&&$&!'*#+#"#"'+)!!)'*%!$$$"!$+"&$'#))%')&$*("$*!#"!#(#**$%#*(#)+*'!!$&"#(%"+*'$%(("%#("&&&''&)$%!##!*%#$&#+)+&%*+!)($)#+"('()#$"#+(+$+&(""(&(+$&$'!(%%*($#(!)$&"!'$&+!$"%!#"$++*$(')&(!+$*!+"'()')%+%&$"#*''!*+*$&'*!'+$)))#'"+%($()!"&""*%++'#$++"#$"&!&!'%*'#)))&&!*'%&!#''(*++'!&$(%&$&#+"$"((&($"#*(%))+%"+*#$+'#*)!")!'$%%*&+"'##!$'!(+%)'+!$)"%!!"*'()"(&*%)&"
@r4090
GCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTNGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTNT
+
*-;B13-0;;H"+&(@44F:$2/;'*&(:GA$F-1.E$:D1;@'!&&*=,7A>:2?/>#:)<#B%-8*,<72C:1%=5&$.D*!*?!.(2),<A4:@H
@r4091
AAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCAAGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTNCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATNGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCAGCAAATATGAGCCAGCGGGGATT
+
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
@r4092
TTGAGCAGANCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCNCATTTATTGCCCCG
+
5EE-G:#*>1>D>5$C$(.=@1?8CC:.&$(.$*FC#A6>GD-H'@3*;'(,<D#G5-?->7278D%*GE;,7A31$>8B%-E9<6&>)G81E30.;G"880&D:'.D<'!*B>H-/$5#+6
@r4093
TCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACCGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTNTCGTTCTGCTCATTACAG
+
H9%C)*3%;@3/E!1(<>:98,>G2-A6=(HF>9FE=B&D2,)+G+H3(+9/F$#&6)1.<,-G"::4>E"*GD5C0)'BG%+'6/5(H4*6#-F!>2'3>$;&B@!&+'13;8-:-60'(3(F*
@r4094
AAGGCGACACCATTGGTTTTGCCAGACCTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAANAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAANGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTNTAACCCGTCACCCCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAGTTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTNTTGGGGCGACATTGTCATCATATACATGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTNTTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATANGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAANTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGANCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCATAAAGCTTTGGGGTGTGTGTTACGAAACGAAGCATTNGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTT
+
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
@r4095
CACNGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACNTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTNACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAG
+
%%)#%++!$!!"&")#!!)&&'##))$&$$$(&*&*%#%$%!&&"%'$$'!&'''##!)&$#%!!&$%#"#(&!"&)%+)"+%#!$#&(&*!$*&!&#"(+"#*)&+%!+()"#++#+'+(+*')$!$!%!#!"((*%))%+%"+)!'&&#&%(&"''$()!**&#"&)%++"'&%(+#%+*!"'%+$!%"%(%(%#(#"(%"!'%'
@r4096
GTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATTTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCA
+
3!#$-3,>C7?>$(D@'35?%7"4#DE"-47'&H%4D#*(8"-5>)7,DG2%@8#?&.)?>?8FC"&;"7&E?$#92*E
@r4097
TTCATNNATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCG
+
((%#$#!+&$($"**!')""$*!$!"'(%)*#$%'"$(&'(*"#
@r4098
TGCATAGTGATCAGCCTCTCTNTGAGNGTGAAATAANCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCTGAGCATCATTTTCAGCTCTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCG
+
H1"$-E;=+3)0%BC!9.!&!'CF-D/CF7?A9*.A=F'A#D:2:E#:#<-'(&'+1F"?EGB$1>16/2&-<B$CF;C,=F<9-%F*C?59#2A;B@D'1@7.F1(1!(5H%)H#;%,4B8@AG1B&>:H4!A'E2'A&&.412<65?(6G(-?"7B!!#2)CE/.+//1A5G1":EB(C5&%/GB;6&+6#+1G7!.=0G24&69&.AE450E;B0G:4!8?=5/'=31>+@:A?30B&-(:@<7G0'9+&"CD2<-=B$*73:12'G'"8;DB4&@"D='01*F;B0$@=-*C53@#41(/2+!!C,1%BG*4='8.*#/+&H+)5/=<&/)#=(!F<'&B0>1*@"72C>-'><',-DE6,":!!/7(919H+FC?F;0#?-6(9A;";!G$,6914/5(A:BEE88<@'3*@*';5H'=+0HA;/>=
@r4099
CGTCCGGGTTAACGGCGCAGTTACAGGAGAATCTGCCTGATGGNGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGANTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGNGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGNATNCAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGNATAACATGGTTGCCCAGGNCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGNGTGGTTTCTCAGGAGATCAGNACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGGTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGCAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGANGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCNTAAAAAGCGTGCTGCTGAACANTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGC
+
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
@r4100
CTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTNAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTA
+
,FD,A"8#F2E5:1(&6G6;2)A9D)&G(F,-94CD2./-2);/4HG0<#@A'=;!0/B$/D7:>(-06*)B*92@0/
@r4101
TCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATATGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACANCACGATGGTGCTGGGGAACACTCA
+
D($G8!.&1:'>-5$)*#1?2C6%3,E-'$/3;*=('13;*(G@>53$-%@:8&1;$620BFB."+234>%5/1>/BH+$/3+B@F#DD(%)4"H/!+;H'7-EG2%1%:<8D1'D+?#C6?)/+A.-+195+01&&F1#!"<2EB6)./0&-%+%,F'?D9"C
@r4102
TCGATATGCAGCTCCGTGCCATNTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAA
+
4)105')(/(,1HHB!/E;D5F:&3:460;$<"4)H<(3H+&G;)/D!/@*FA=9;@=H35%/H4?E%:%,?/!+!.3>(B.G63A?+7!+)9/&E/#2%75"(28>EH')5$>,H'-H.0>&A
@r4103
TGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCNCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATNGCGGTGCGTNTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGAGTGGTTCGCTTATCAAACGCTTCGCT
+
*@+!!F3B58.B+1A>>0$;305>3.'F+>=1&@94.<+11,1709F>?78A13EE+1()<8G/8-9H,@"!7=)D!*D(?;(87-*:$8%19E0D(>C0$E3+%0<?F0=;9D1)<@3#<6;/8;.'(E92H/5G<'/@;*$.0))F*6,GD#$GE3E"A=<8+@"7):G!=!/<-F+8G6+E5(E1=/4"1622!6$(%/A<+AG?C)2#5*9+D@@3:;3-$)?3#<$<B99G-.3B6+8(-C866=:@:?)$.=F#>E;68."-@*9CAH3+;:*?!1,>-*"$A14><#-:337/F:+!<EB".$=#:+2$8A/61($E?->FC-0'2,'(74D1E!,+.&>":;
@r4104
NGNNNNTNNTNATNNTCNNNTNTAGCATAAGGCTGNCAGCCTGATTCCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGNTTATCTGCATCATCGTCTGCCT
+
&)'%&('&"%!&#!"&'%')"$!+'+$##$#!!"#"()!%&)#&!+)"!$%"#(%+'(!'!*+!"&%"+&(##%$)'(+'+"++!'""")##'*!&$#('+$"%&'*'(!!)!%)!$+()#"&#'!%*!$&!!($)(""!)$'!&&
@r4105
AGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGANTAATATATGCTTTCCANTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTANGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTTAATTACTGATCGCACTTTA
+
11F9/5).6H3.7>GG&&7B227D.2+?525C4A#/766?'?#?&;"FCB,(8C.#.=-@C4@5869!43@H+H."4G(8E(B'B-+F%:#9%2504B/3?8/(2)A@$/AH3/@*0HFG00+C2&HH.?).!FD*18''A"0;3'!A"5F;9#)/G%,89H='=+2$2,8$7A04)@1%/>6C'BH683&&F*>A.*4E)?>@2"'HH3+>DB(E88F5)
@r4106
GTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCNTCAATGTAAGATGAAATAAGAGTAGCC
+
-D>;<4>6C2'68:&40/57A>76GH-"&2+C53#+$1HBB/1?5,28'1C.)/E$87=4?5&>'7;7:C
@r4107
AGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGG
+
=E4%C;%>,20H*,H-#G0;6#6>*@"HH)FA2B<-9-'%$$/@@#D8DG/C0&1)9/!";5DEH13')51+-F,>?G34+4A5#:=.B:8'<0DCE+;2!"2*"=-1(&1**:7=3<$.$5562@)-GH:6@'$D*5(*4C4F(&:(G7(833D95)A2?;$
@r4108
AGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATGTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATNACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTNGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCANAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAG
+
?='64!&$A3A%H4C,&?E&G=92.7*/G(<@:?@BC-+.,1)A:C'0,D>-9H@F64%6:.(A-.2):4E;528D,!=.<=*,($7H?A.1CE!1F*4<44!A)(=.4!98(6<7B74G=,$!)"B,4G(2/:G1=>(,**."!E:5)20(8,!.&GG)0<!47'.F:E*%3@=:15:!>(;B7C(H7@D3$F;G*1+#4?2$C%+.+EF<4G+)8('E.=01DGC$>/86633(D3#F+0+9'C$&E8H)?06=@
@r4109
CAGCGCCCTGAAGGACCGCCNTAATGCCGTTGAGGTGAACTGGATTGACCCGTACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACC
+
(+)+#)!%&'+!%('''$(%*+#)))*&(#'$!#(&$)(!&**&!"#)##'('*&%(+'#%&&""#"++"&("'!(#!*(%+($")%*&++)!!"$$"&#&%**$%'+$'$!%&&##'&))!+")$*!&*!*++#&()**#+'))!#&*$$
@r4110
AAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTANANAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAAGCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATNCG
+
&*$$)*+#''#'%$#&)#!!'%!*$"%!#*"*"&%##**$&($#&+)*)*$#+)##)#%%))'!$&$))!*!"&(*&!'($&$&*&''*(+)!*%*$&$%&#!$+%#+$&(&&%)*)')&)$*#)!#&*$$!&#++$*'(+")+"$!&!+&)*%)"""'$*)"$#*"!+#+)'!&'#&%'%%#!'('!&!$%)!%'&()%"%!$)%##+$")""(!#))!&+%)*#(&&(*$++%++'%#*##('*'&
@r4111
TGTCTTGTCTCCATGCAGACATGACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTNGGCATACAAATATTCCATGAAGGTTTATAAGNCTAATGAAGCCAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCT
+
<-G,&&#!1'F(/&6BF>#9D,;%25"-%H'5".@B0C;C%97+9%EA))A+D!96:-AB0"C-+3H0>7E+D!1!"7($B3,E84F<?)2HB)-?D1D,!.72B!#F-G;30DG&?96.:.ACE#.8C:3C%4'<"87"=83'>)?"9&BH>61!7>&E()%>8/&F%,/!D9+1AF%C.?";?<6%+18H"9F;5%81EEFD=;8!4,?=#'"%844$D;1!0"38*;.A;0:6=0A@G7*C'73:9D386<3'.@B??5!=F)<5-'@&+F(
@r4112
CCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGCCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCANGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTCTGTACATCGACATAAAAAAATCCCGNAAAAAAAGCCGCACAGGCGGCCTTTAGTGAAGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCCGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCCGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGNTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCGTCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCATAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTNCACGT
+
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
@r4113
AGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGNTGAATTAAGCGAATACCGGAAGCAGNACCGGATCACCAAA
+
"EF=<#1%=35&E/?>B=9119)9>@'E:5@=4!<#5/!7:,*3)D45F,7&#'(;*="D'8C/528)5F"=70>E%CD6
@r4114
ACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCANTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATANAAGCGATTTAAGCTAAGAANATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCNTTGTCTCACGGGCAACCTGTGANGCCGACTGCGATATCNCGGATGAAGCA
+
):>':;(?H5+%A?+E,.#0>,>A(,+#'AG:&.;##&/F;$2D.5:8-E!,'%GE56F0%--=+!.18*5@0.+!D!9/)$32;>,B2FH*>@4@HA6GEB1)?+'D<.F*!*?1E3@CG,!:9560+9)?B186+'A7H%7*50>(!3!608,DH.CAGCG3#6%/+,2%64*4-5%@D)>D+3H%<@:+"%,,*=;839F&4)*DDC/F75&3A'./9EC2/<5D6'@5C9#!H7<6@@%E=@;.'7@7"?/84/4<621D#+&''*(>B6H)+0&>&H1@>2E&.!H71DC%#%D!5!HH/:F.,H>;HF35:!:40!?5;:D;23B(#=+-8%"6<C)/06=*8E4;!'7D$D%/#8G%=8-<&*
@r4115
NACAANAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCCGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACG
+
+>*H4/D1EC<6"#914CA)3;3$7CB1H:?!H)/**,,&-21F<,(;7)1,:(C(A/57-F7-#-13#655D@5?4=?6G<4@H$+GB-"0("E%>5)2-1.?4@(3%*,E$**5(3155C<)737G1(CB>?AH-+H)488=G4,!&.-&+&7
@r4116
CANACGANNCCNAGTCTGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACANCCCCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTGACAGTGCTGGCTGAATACCACAAGCAGATTGAAAGCAACCTGCAACG
+
*%!($$($$("!$("$$+$"$!%*"))&'""''#)$%)!&'%%('&!'%+%%#*%('#%'$'*%)!#%('"'(")%'+++++(&%%+)%+%#$"++'*(#!+(&$+&'&*")++"+&'('!"!##$(%"'+&*"+&!$+*"(!'&*$"'$$!&($('%(!#'%'$&('"++$+()'(++**'#*&)())'$"+#&"(#($)#$$%$'(''!##*+&&)+'$&(%+%**'#"%#+$!**&"!$%!&''''"'!*"%'&""*#!"!+""''(%#'&%##((''*+%$%(#$$(!%'#)!!'%+$(!)&()"#$")#+$)(+)!$+%)(+'"&'!*(**++#+
@r4117
TCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCCCCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCNGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAANATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCCCATTCACCCTCAA
+
.$>)2?+#8-D@3)%+/GC14?E2>*F&E.GA0H-*&,+9>*73(8D(>>11-+/D(DB):>B'#,6'31,GC#24)%@!7C&+5=%+F6D:<$#>1#32C?"91?++E3AD.@#7)%-5@=2(.BD<AC+95#;41&=:,G?#F.:'<!F3&#%61?+;-;F&@*>9E(G103("$.HE<71&F5$<&&.2->2E=,=EC92)=1$(),95.9G18!3#=0:,ADFB0'7/@</-D?#<.=E7!-C09BD/=D(AH2;%58-$A,13-*%>.7F:?2$CH*<(4-$4+:!;??0F4%%;H-@%&+):=-::8>:84C
@r4118
AATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGGTGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATG
+
/-?**81??@D6.$-.D4!C)>"!*>;39>7#;-B86+>&"D+4D?>@$.52!:0F)>@/$/>B+>#1-4:B9?/.@,=AA=<G>013=&0H7'!*:4#E,?&/D<D74><"F*%*-*?"GH'B2=945E4;/%%78E;,A0C@/!B2'4&,$0C!A@E>;-@8:G$5?45"4+"*F.&&=A-7A:5=@H:
@r4119
CGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCNGTGGTCTGCCCTGGCTGAGTGANGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAG
+
(8F$:&(!-7$9#CD.+"",5+:5H,3"-CGF=C1EC@7')44H-$29.%#)F2&D8-"-BC./)-C%=9E.E2;0=9#770)"&>7/144!)=D>>,$"=6C:-/=2"35>6):%01.-#E="$%3:$,@71$8(#&4-B8D/1=-/D#26)+@:HA5HE(*&!2)6A/,GC3*)AG9)&>'$@#?E.=</-;
@r4120
CCNACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACANCGGTGCAAACCT
+
#&#@'@/0.8A%*($'139>)C#:2:&3&7>%4'9H#B??;9!83:(;1%9-'0,'@F;0F6>
@r4121
TGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGNGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAANACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGNGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGNGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTNTCTGCTGGGATGCTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAANAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAANGCTTCACCGGTCANGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGA
+
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
@r4122
ACNNCGTGTTGAGTTNAGCGCAGAGTTTNAACAGGTGGTGAACTGATGCAGGATATCCGGCANGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCA
+
#)"&)(*+"$''#'!$+#%$'%$+$(+*(#%'!%!$&#'"'")$+#'*#+)+$"#"!"#"%&$'$)#%!$'('&$!%$+($')''#'**")'!*$%$(!'%)%%&(*)"**$!'%+&&&$*)(#"$%%')"(#**)))'$!'#$!!***+#+*$%#'+#$)*)()$%)$&
@r4123
NTTCTGGCTGNAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATC
+
$)"-'=&3:!,32:66&H4)2@BC."/?.)C;$?1B@A<G,2''$H)-"%->EH'>1A#;(G8D-+*9:+)8#;(F..9--(222?!&/@?
@r4124
AGGTCTGGCGAACGGTGTATTACCGGTTTGCCACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCNGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAANTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCGCATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTNGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTNTGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGNATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACNTTGCCGGGAATGGCTTTGTGGTAATAGNCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGNCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAGAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTTGTTTCTCCGGTGGCAGGACNTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGNTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACCCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATTTGGCACTTCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCNGGCGAGGGAATTACACCACGTGGATTGGCANCAGAGCTGATGNACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTNGCTNAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCA
+
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
@r4125
AAAGAAACTCTTTCGTAAAAGTTATAAGGNAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAANTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGTATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGNGGGCTGTTTNTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTNGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGNGTAACTAATTTACTATATGGTTTC
+
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
@r4126
GCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGANAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAANAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTG
+
=9/;;&%G-=<GF:3#0$@,#?9*GC@G#6#2#$>E"E-.@,/)%*/.(@@D3/H-6+9=68#,;"C)*>5&33'A'7"@<C4E).D?8,<2'"6"BC@2=+3;<=68<6?!8(*7=(2'H6<3F/C9G+C3'0G"3A9:C8'-#F"/!2DDB)')9'4%9)4C$'8-(0@22?*7G40:6-5"E<1>4*"G>H:/:/1-5@!DCFHG;A?F..54-F'5!FD==BH1=.A%,!HB",B6D6,%!65;2<:>>A&'0E>D-7'%00)9$743=@)7A6G.+.+!'<E"H?/E%19@B9>=F?;"@93A3#&&E=(:G%*,"":2)9EG><DE=:+3?G$/08$&76B%"H!<HBE0)#.D2?>,&4.->89"3(.H:@?-D?<'')904',
@r4127
GCCATTAACCNCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGAACGCCGGAANCTGGTAAAGGAAAGGGCCAGGCTGAAATGGGCCATTTTCNTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGNTGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGGCGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCCTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTNNTATACTCATCAAACT
+
$1D@:D$!B/581+?6E33G@&C=$!6(1H$&)F*&>&4@542'%.3%&F10;*!7311#(.#9>5FH--9@;A#;B-&&9.-1.-HBA@!=1=<D9@4B64*/5=,?AC$,)?-34G83794=#3;2'*94D*'<+;$C82D&F-(/1/<*@>:/A#+GB(8HB!.G9@#7;F=(-,12H&55"G":B*G<HA6G7,/7H0:-84=+0&3FFD?0?:E=GEHB6<5+2A8)*&,?/E75;7H,CE:6C62/GE>1B#+"(">%-/651/,F02(B5F7FG=E#A'.9'E?'H"0D"A$6A;,?$@A1""F(512A36$H=B=".;;9H>3?&86@3AC*,)4.E*0@5:=:#.2E;<>96/H:9(H"&;2B(3:?.)-@,D
@r4128
AGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCANATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGNTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCNGCAGAGCCTGTTTCTGCGGNAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGNATGTCNTCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGT
+
09)&6+!',22/9/.:>-.<%DC9+),#16-$G4DH6?<723%=GH-+0)-3E'H&;'3).%G/&>C3#*5F$-C8:,D+@F/G-HF)+3=+(=$78<B:/H1EAE))@06++-+#;F"=+'%>3'&<=4F0&B?</*,C(5!!*CH<34EA"B:B'B<&GE,9%38?E65.:)-$1"8,F7CA.8#A>@8,A>65EF"64?D=3A<$+2+40H68+8G,<%-/$./(D0?#3?@=,1>5;-805HCF+:):.)9=BC;1%(+?*F.#%&<2C)@'*5+5@/4404?6A>H9)H&'D4(4+?;6<@.,@A@=$-315@BF)=6H:0280'$AG9%'$?8$&;",;C>3@+70-&2"83B%-;:48$/8=*>B9H97<B:F,(2<#G3F/GF&*1D4=,'+HA8)"!1>/HD
@r4129
CTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCANAAATATCCGGGGTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCNCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTTGGGGATCACCCGGAACAGCCCATCTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGNATCCCAGNAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCNGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGNTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTG
+
BC9!6E?%(*0.'0@F8$8;!)A7"D,+<64(,-;&4<7?;#,A$5817$C48D1!&@<-?,,3F"5+-&%.'&1(CH7GD%-,&)*7??04B#:-:G&:2.1&.**5"17E:.3E4FE;;5+,);E+2"40D=;<;=D:"3++B!71E891>5(+!%,9-="D=<.$EH&2?31-';H%/:C7%&83-:51>H1,<14ECF(:3GFEB(<!3"E/,+@01*G"):4$,.BHF1&+*+599.3.BD'3:G:0#+1"<%0E!F$5#<5=:/!,!$2>"2#-0;$7#==?F4"G8(%$/"2D@:0E@5'0F$&D75HH>:0)C.2'C--$#+<5BD*;.2G@5F/G<H@2=E%?<2@;7&?D./88>2#'89!:+)<1)C3962%F%/'G8?:9/"C'2'+(C=<##'!0B06;C<3"2(FC,D58)9#$0@4-HD2+.&),9D#-&6&'/>E3(3<+"3!.2."(4GG/$?A>B2<-$1+=*+*-=G6HHH%!#01:(0(<!2,->#"-<FC/8/G95EF*7+)!$?$4<@/)
@r4130
ACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTGGAAANAAATAAGGCATTCCT
+
*5E0'A,"C>;BG'3"3.=.#$6"7G1;A=D975@8*4@-!()3=!B:D;07+&3"?=),@B3?@-3&;%98*H5&/6$:B4C"6>:*40$+6EF4G"/&@.>H)@5(@H34*+"A#F3B0#;<;="<@,78?H))
@r4131
TGTCCGGGAATAATTAAAACGCTGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTNGCGTGCAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATNTCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTNCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCT
+
.0>2-"';4#-4%22EB5=?=G)2E5.":F!331)EE4H5#6359:>:5;)76#9"BG=B?*&2?0'6?4":&A4G)F2?B4B2:!&0('@4%'#4<>H#H9H':(7@&C,/&*GDC,:E123%H=2B/>FC-8/C)/'%D3?857BC$)G?)<9C>*5"H-;*13734&35)B,4G*&*)-+,D+?"&&:/3-B:AD35?H0;B!<B@+H/E=276;2!3;7=$%E-83C<GB5#)$G/8D21>4+/?$A1&!)6;9%?A.29F9//HA,5:F"8CE8'D6F"$H@228)=E#0G!DH43(4F<F#2#900@@1%6&=C>)=B32>+#486F<71+B@=8><D.%9)?@E',2EF$?1H3(37C5;3,-/
@r4132
CNACACTGAATACGGGNCAACCTCATGTCAACGAAGAACAGAACCCGNAGAACAACAACCCGCAACATCCNCTTTCCTAACCAAATGATTGAACAAATTAANATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCACATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACCTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACA
+
("+A7&&'C5@H,*E=3'.H8+(8HH5?#.F$.):7#529*/(10@?F&3BB,&'G.3A"';.*(+!'?-!DC'<10G<9B-<F/?0<7B!%5;(.1"*@G/'/'2'+@-70<G.;9B7-&;93/,1#105;<&E294H7@605H@:834F3=?3?;@'C9B#/:B.B>6=4#0#6H#;.4:&.BA7/(*D<H%&<'BDFB+"8.;$$.?G/-2A-17,9.A<D1@3@,46."-;E:-2+%#0B5D<6&.AF"$G*A(DB<5A?13#D?6*GAC4@#:2-3.;=%=*C5-4G>9C#D7,7HAB'<H;2D%*8<G9?'22
@r4133
GCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGA
+
'<4G$-9'0*8D6-1$3D97E..*7.D?4C/AC"<$AH"H20+E3G5F)($#2@7373:<!.!-"4
@r4134
CATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACANGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGNGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATGCAGCGCCGGTGACATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCANAAAACGTGCCCCGGTGTCATGCTTCTCCAGTCCATCCAGTACGGCTGCNCGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCNGTTGATGCTGGAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGG
+
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
@r4135
TATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCAGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGC
+
25H,H>+#)52:"3128A"0*=/8E=G1"/$27>7$C5,//*-#C,9:C66!%(4"68/;?<58&G?@9B22@!-F3H;;.:.CEEE.:.:H8;;'F:4C??=5*2E/D),(*!+)#B0#*"0*C3E>H/A;4(&CF7;6"%;)/G"D+#C7%A>!D90G>C:#FFCGGE9@>0F-1?/3A-(@BC#$F)=5%(5)3@&,D6':979:%5*>5>.H:DD/061!<3(@6("F.D90$*AC&A.B"@#9-16+*<E6:82)2),!DA.FE-7!=BE7@(,%757G-B4>B?:(=!+E7(1%E'!0@%942$FD;=&$(-259=74308(%F'&0E0%(;E,=*+(1H3F=.5;D@DE.&?.85!<><%>$!/<G3D#6"57'81BB"F2-.)/?='H1@<A:21A"#+1.<2%#632B@,A'3?(G&;;4"8-EH/%H7<!66G#769F&-1GH0H6
@r4136
GCAGACAAACAGNCTCAATGGAAAGCAGCAAGTCCCCTGTTGGTTGGGGTAAGCGCAA
+
).+<D.'6?/&&/=.0"E;/(&+8!E97,"84-B.;4/6A0&>./F(.1?D=CF)D''
@r4137
AGTNGTTNNAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGNCGTAGTGGCTGNCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTTATGACAAAAAATTAGCGCAGGNAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGNTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAANTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATNGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGNCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCGTTTANCAAGTGTGTCCCTCATTGATATTCCGAGAGCATCTNCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCATCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTNAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTAATTAACTTGNCTGACGCCGCCTTGCCCGCGTCTATGTATCCATTGNGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCNGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCNATCAAGCCATGAATGTAACGTAACGGAATTATCAATGTTGATTCTCNGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTGACCCGTNCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCATCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCA
+
'"*#&&!!!+(%!!+&)*##*%#!#)+$!*)&$')!(&)+&*($"(%&(')&+%%+#&"#'+)"**!'$%'**+$!$*$)'))$&)$)()*!*)!%&##++#'$")**)*%!"#((&&$*+)&#("('+&#$"'''(*$%#")&#'+$(%+&*!(&#&!$$%)(##"'!)!')!)"&"&'$*"!"++*$$*(#"++#+!""!*%(("+"&)!&*$***%+$'&&#(#)'$*()+!$)('#(%+&'(""&$*(!"%&%%#!(&&#!*'!$(%&(+$&!(#"'**+!+%)(('&'(*&$(&)$+#"%("(*&)*'"$#%%!#"'+'!'*%)%$+!'$%+'!+$#"*'*)#)!#"$!$&!%$"#"'!$$#'%!$&&%%$&#)&)&!("&$))'$(*$%"+(+%#!#))&!("'**&((($'%$$+!%#'$$!(%&#%&*)()$&(*+#!$+*&&(##'++!+"&)#!#(+%('+%+$!$"("%%*%+$#$(&'(&#)$))*&%'*!)*##"&$*'(#"*"'$#%%#!$(()&!+')$*!"&$&)+")"#)'**(+$***"&$"*%!'%+&!!&!!"#(+*$!%(&($#+($%!$)#(%$%*!&*#(*!'!#)""'#('%)(*(")$(#+'(&)&%+'#&)#*%"!$(%&$!#$!&)##)#""%)!'#*))%("""+#!"*+*&)#(!(&(+&(%#+&&#$!%*"!)'#&()"))$&!%*!!#!+))#&%##+*+$+!!$)%(*'!&"%+)!+!)!)$$+!+%+"!!$'&)*++("$&%"$'+#%)**()'#$++%**$($$+&("$(!$%("+!$$&(#+!#'!'##((#%''"%$$+!!+("*"+!!&%)$&!#!)+!+"!'"()&(%'%+$$+++#!%('&*%#!'("++(("(+(("("(%)(**($&%"*##!#)"%#&""#+(%'!+%!+#)('##'!("#)#%(!!'#!($#%!+%$$!*+)'$!#"&$"!*(!%*&((!"&+'+&#()**$!**")*"$(&"!)##*))#"%!#*+%($%#&&#&'!$*&)")&&)#"##()&*!+&'*)%!*$!&&&!%)')!#(!)))(''#&#+%#&)!&"'##%"&#()"!*%$*#*!+#)(#$!$'$*'$((+&!()!%#)!#%(#$++%*&)""'#'&(!*+$+''$+#&&$!'*%!&(()+)'#*''&*+$!&"#!$"!%!+$(%%("#'$#*%*'%&*$&$'#"'(+$$"&*+%&)#$"!%"%+'(#$"&#$(%)"*$#!"!#&!*%*%''&*$'%#&#(')#%%(*'#+"')*"))'*#'&"$+"+"*"$'#*)+#&#&"(('(#+($!('&%+"+$))&+"*&!$$(*"&*#%!)'%)#$+&$""*%(#$"!%*&'%%*&$*(!!($#$!**(&+!&(!!!&+('!()*&"%"*#(*#***#($#$%&('"$!$*)%%+&#)"+#()#!$)!#(%('+)$)$!("!!'*$'$($((#)+&%#'!%%"+!*&+*)'"")$!%*'&*!%$(%#')"!)+%$#)#)!
@r4138
NACGTTGTGNCCTCTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTGTCTGCAAAAAAGTNGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGANCATNTATTAAGCATTTCCCTATAAGT
+
!*%)$*#''"(''!'&+(+#&)&(*&*+!'!*)&$()("+'))!$"&#%(!#"'&("+#))!*#*!&%*"%')'%&%&$%'++#!""'#$(+&&#&*!)(!&'#'#%+'!$'"'+#)+(#"(%$"'#(%*%&+%%)%%!$#"%&(+#*#%')+*+&!"(#
@r4139
TTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGAC
+
<)8$%$=,4;.('8!FAC,A,B/"..CB&!%0$!E/"<)#;D+@,-!92(1F+!E"',#,)56#,+C6-D'C@"%<'*-@G.8D9>2&"?6;=%1<?@&7"$-7(<CDAEE<:9$D4
@r4140
AATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAANTTGCTGANATTAACATAGTAGTCAATGCTTTNACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATGAATGAATAAGTGCTTACTTCTTCTTTTTGAC
+
DFA.2A#FC=+*B6F7B52DE.>?B8$!/;1,C(!B*5;62<=E90B"D&@!(;6'!-)<260F*(<34*&6;H=G#G-815D+D6"*C0-:;4,.E;<FH-A-@@,&.847DFB.'G</A=G'G6HGA;,971.+.1&F,)6C($88/:-1H-?#A$.E8;C;=C""2(1<+DB+?,B)F/?(/4F-><=D%01;C"4,&/EA)G(!A"C,4;$5,-H(-42B!@2G36D(B)4(""1
@r4141
GTCTCATTGCATGGGATCATTGGGTACTTTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTCCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAAACACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGNGCGGTCGTGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAANATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCCCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCNACGCCTGACTGCCCCATCC
+
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
@r4142
GTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAANCCCNCCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAA
+
8>C;190A"#?)8$);!F94"=<6.HE4@(3AE!<:*>3B!8:,-(2(-D!%5?53G<$!0>>15$><4G1&@?B?9C)1@@C#)88H-6,C=(9*<9%51E
@r4143
GGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTACCCTGCGGCTGGTAATGNGTAAAGGTTTCTTTGCTCGTCATAAACATNCCTTACACTNGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCNGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCA
+
B8?.,:.>99"$$**8A-=&/'5:64*G-A6'C%A=;&E9GC!HF?./7:&3"A!3B5/3%=.1&7(&)%2F:,2'5<84GH.')*&@+%B+F7D,!::8<;=0C-.03=?1!<F9D=)=H#A(*(D26%A:36(E!5'@9),;)7:";!EA;1A9+-A7#!/-'?$2A*(G=;"A(%-(2B'%29>4C3-788!A&-5==.A/G&2@!35'*5D,)>=@!%9(;8G0GB>*6)A9*'2.:#?7.)8":66+47D%"07"&80+<@)#;?!7+/E9;/;E95?3'#12'0)&71?71G/1-?;7:%/C3@4.7D%00;A2(,/))F&:;%5.#4"7-:5=);5HE<"#&4&"E8$;@D/8"A8-14C=FBB8E5@,9-+D)4E.$$1&.3",*:73B:"4+"2E2!@3A;6G%?GDC214GD+0B5E:@6<F5:"=28155;7&#+4#6<"!1%"8(;<0+#A/,;2"'#6F/&
@r4144
TCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGANAAGGCGTGTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCAGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGNACTCACACACAACNCNATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTNTTCAGAGTCTGACCAGAAATTAATAATCTGGTGAAGTTTTGCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGTTGTTTGACATCTGTTCATATCCTCACAGATAAA
+
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
@r4145
TAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTNCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACAGTCAGCAACTGCGTGGACTTCAGGTNGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGNCCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGTCAGAACATTGCCCTGGGCAACCATGTTATCNAGTGAGGAGAAATAGGTGTTCNGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGAAAACAGGATGCCGTTCATACCACCGGCCCCAATGGCCGCCCCCCATGCTGCAAGGGTGGNTCCGGCGGTAAAGAATGATCCGGCAATGGCGTCAGCCCCCAGGACAATCTGGAATACGCCACCTGACNTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCA
+
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
@r4146
ACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCNTTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGNAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGA
+
@'+H>>"H6/%;:6"ED;78)=<3E1!5!!+(:5%E;'909+5=2<:/!A?;92H-7-5=:<&-"E>FAH#'FC+0)5D&'&"(=>H$3D:..E2-5G6&*2'H8G<='#$C0=,,.:F0)A%ACG'7(,8H$B/G.8#GCE5!,+4'&'$A?A3<+..9<H#/0E-A<7!!?47%3*81;37-41'-0;*:2$+*<.#1@.%2&C%03%0'1?)GF'.3!26,+$E.4EHG1A-D)71+:FC8D-8@7H496#8F<4"@.337
@r4147
NCGCGANTNNCNNNCGTGCTCGTCTNTCNNNAGTCCNAACNNCNNNNNCTANNNNNNNGTTNNTGGCGCNCNTNCNNCNAGATATGNNNTNCNGNCCCCNTNANCNGNTANNNGTNGCCNTNCNNNCNNNNGNGTANANNNTTTTNANAGGGNGNANNCNNCCNNANNNATGGNTNCAANCNNNNTNNGCACNCCACNANTTCCTTCNNTAATCCNCGCATNAAGAGNNGNNTGGNGGNAACTCNNNNTNANNCCNNNNGGNCTGCNCANANCANNNNNAANNGANNACGNCNAGANNCNNGNNATGNNCGNGGNTNNTCCNANGCCNNCANGGNCNGAATANCATTTAANNTAGNNNTTNGTATANCNGCNGACANTCTNGNNTNTNCGANCGNANATCAANNCNNTGCNGNNNNNNNANGCGNCANNNNGTGCGATNNTNCTGNNGCNNNNNNNCNTANTNNCNNTNNNNNAN
+
!!#"$$!!"!!#!!!$!$$"$#$#!"#$$!"$####!$$"!"$!"""##$!$!$#""#$!#$!!"#"$!$!"#"$!$$#!"!$!##!#"#"#$!"#!#""##$##!!"#$"!"#$!$!$"$!$"!#"""""$"#$!!!""#"!$#$"!!#$"#!"#""$!$$#"!!"$#!!"$"#!!"#!"$"#$"#!##"!!#$$$""!"!!$"$!"$##"$""#$""!"##"###!$#$"$#$"##"!#""##$!!####!#$$##$""""""$!$#!$!"#!#!#$##$#$#"#!$"$#"!"$"!"$"#$"$"$##"!"$!#"$""#!#$!!$#!"""!"#$"##""$!$"$!"$$$!$!!###"##$""#$!#!$"$!!$!"$!$$$$$!"!$#"$"##$$"$"#$"$"##!$""!$#!"#$!!!""#$"##$!"$!$####!$"$"##$""!$$"!$#!!"""$#"!"$$!#$"!!$#!!
@r4148
CGGAACGGCGCGCCATCATCCGGCATCACCACNTTAATGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGNCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTANGCATTACAGGTGATGCGCGGCTCCGCGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGNTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGTACTGNTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATNATTTCAGTGTATGACGACCAGAGCGTTTTGTTCNGCAGCTGGTCTGTGGTGCTGTGCGGCGTCATCCTGCGCATCCGGATATTAAACGGGNGCGGCGGCAGG
+
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
@r4149
CANTNNNTNNGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCNATGANGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCNACTGACTTGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCANGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTNACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCNTCACCCCCAAGTCTNGCTATGCAGAAATCACCTGGNTCAACAGCCTGCTCAGGGTCAACGAGAATTAACGTTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTNCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAA
+
#)"**#!*!"+""#%+*&&#((#!#(+%+"!%%(+$$#!%%!%&$($"%'&&'&&)#!*$!('!"%**%#%!#%$)+$&&!&#!%)("'++)((*('!+#)#%""(("#*$%"+*()*%("""'!#$'%$%(")("#*&(+%+!+*%"#!#)!'""$(%(()!)+!++%%!)*!$)#+)%)+$"*%(%#)("*+$!+&$'!'&%%"&*&&$#+"&)'#!("&*)'"!&+!%(*'!#'$++)"##)(#$%+"&*%$%&!((#'%&!&!'$&+#')(**)+'$*)#%#+&&%$$$$!$)!&%*$#$&%&"'+$&!*))+')(%*!"(&"$!+'&!&)*"$**$(%*%$#+")!)#%!)*$(%'%"%+#%#&)"(($*$'"!*%%%$**+*)"((()"$&$'+*!()$)++(!#&)&%#%*!'(&$()""#$)+#+)"%)&%&+$%&&$#%!))++*##*%+#(!!)*"($((*+%$++&%(*$&#
@r4150
NTCAGGGNNACTNATAGNCATGGTGCTATTAAGCATATTTTTTACNCGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATGTAGGGGTTAAAATA
+
$)$*)*)""'%#$*())$++"))%!("!*$*$($++#+'*'#'*+%)!*#&&&"%('+'+&!'#)*$$"#!')&)"($!''*$+&#!#(!'&"+&*($)$&"'&$$)&%*#'#!)"$%((%**)"*""("")*#+#
@r4151
GNTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCNGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACNATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGCGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAA
+
)-2*'6<@:#>1H/)<BC6AE%-"C?B"0$C@,0#H#E'"8;?.?$)2)(*E';8%D>C@D.1*/,-5.1C2=2'(C'E/'<>BA.)*$<8&H+"0673>(&B!"'%2316.=15@(8G(D74<6+"<EDH$+F=CFG8323-!F0/3;DC6AG6#&*?01(AE*D"2.5&='%4!(:38C"H'-@*446C/A&)54&@(<$(2:2<!03=E"%&5!A+B0G##*F#F85'"*.$53*7-@07=<,3G'=&0>05,(!D8C,,"#@BD#78*-0$A0*@50:G",96GA/18FB(H385'F5'!B<%!E9!>?4E00BC;;62:,3B(G8/<$C"9AG+%4G(+!9A#-&7/B4>F5$.(B7<H0+BE>#6-,>=".+7'?B+?:!';"(/8('(5/)#F-H"+*=)9"37=BBFF2A/)+1-C5?-@80G/">*.D70!H8%/.9-0'8)&)8+2FG"E<!+"A"'==A<6@25$1379G1
@r4152
TCTGACAGTTANTNTCGCTCACTTCGAACCTCGCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCNGGCNTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCNGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAG
+
)!*"*!+!!)"+!&+&%!$'())'$)%*$(+(#!%+"#&'*!'+)&&!+&+$*)%##(%'+*)&!#!(%**"&)&("""&%+"(%"&(#$*#*"'''&)&)!*#!"*!!!$(%"*'#$!'$*$+'++(++*#&'+!$!!$$)"**"''&$&!)%"*&$!%*&')"&!*+#+"&+&"!&+*'%'"((#((#!!(#*''(%$)%#"")'!()&+"($%"'*!+!'""+&('('($#+)#'%#
@r4153
ACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAANGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCAAAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGNTAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCATATGATAGGTTGAAATCAAGAGAAATNACATTTCAGCANTACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCT
+
HB7@A6=-,90*673,/B*,?;,:CC<%4*='010/H6-+?E.5-E&-D3&376=-'2!&C;*"#@94;;?3%;.(?3?/"'D.4")?1$99%"@&39((.'G&!G*)@*)"0;2=>5<%+%5F@,F9./+-B(6E"-!68E+))%4"7(?+8D41CD;CB*7G85/?G*"9=5-0F08)@46#EC-F%15D@G<7BC>F=G5!?,GF*$D7",#3:&;/#7B@5G%E@:4'=6="E3"/H43BC.7:")?;$-1.$5+&D$H$D%,-;5$F=-)-/"+$)<7E(6)9$F%4"<*D019.9>3=C/2-E(>98""FA=<>:"!$A09H42E-9<GC;#A8-H(06$>?1*&9"=!7;C<-2738@!D,B?/DD.&A;G6HH;3H@.-5(/D+>=E8@>C??%4D+"F5?279/8&'H>.F.")2E=,,'0E!9
@r4154
CNCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCGTGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCCGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCTGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCNTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGNTCAGAAAGCGTGACGGTNACCAAATGATTCGGTTTTCAGGAACA
+
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
@r4155
GAAGGGTCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCNGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATTGGTGCGCAGACCGCGTGCCTGGGTGTTCCCCAGCACNATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGT
+
F+D(F?39+:13259?8/4!4BD(FBB,7?D9.56)4+==H$:!A8!"G%7A)-+#'%F:'EE&$78!0/BB#&'+.E/$(;<(B:#-1*8;)6?=D?$@%!)AE0,/3*F-H*,A8'".(.)1E9DH,HG)(,(@,FF9#C;;1!5><G21%%+5:.5:0,7-+$3<FAGG/-*)H./@H6-+-=-6".-:>78+H:*?40E9=+$G)F=%C$9F!$)#BA.C$=/G4E?&(7B/)CA@!&3>H&*@5A06+!;&*=%>"46+!C%-,;=,="@4.E><9?.@(:*3A,>6%7(&=(F.+;6B%4!?"'(3.',2B?39",A497>B"BB7@"6:A1
@r4156
NCTGAACTAAAACGTCAGAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTGAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCAC
+
"2.$+95BB+=GC1>$+60466.;$28:"(?$:(7%H%?!*!7A.%2=:/&=F=C@H15)@4H3>;0A/"6G6"2%3:F>CH)<58%5"H00AB&)H-</,1D,D!-"'%C$DB>C4$:4=3;=(#C+23#-?=?"?88*-@;@+A&(0!21@=G>:B$EA9!B>.%4FHC3C&:+3.&5=<E456%.
@r4157
GAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTTAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGAT
+
4:<!#*>&@%1'.B:#4C.=')G@<23*&FD>(#>:A@F<.:?-48C/BCB/:A:.(9658.9C/0C'(%C!DF-0D''*0-@43<4E,((!'F@*$A/83H:&!#5;":0-95)-5&5++)4'%-A<F6%=->!?@/@=68D20AH>+BCD6@5<#0D<*4?-&!&71':8(D4G*'?9&=6(&8G-/%3A7+3(.1+AD084/<;A
@r4158
CNCNNCNCNNCGNCNANCTNNNNTANTNCNNACGNNAANNNANGANTGNTACANNNANGNCNANTTANNGNCNNCNCCNTNNTCNTNGCCNGCNACNNTTGNNAANGTNGTGANTAGNGNTNCNTNNGANGNTNNNTACNCNTTNTTTGNTAANNANCCCNANTCCNATANTANNNNNTCGNNCNNTNCCG
+
$!$!"$!$#$##!$#$##$#!!$""!#!"!"!$"$"!!!!"#"$#!$$#$#!"""#!!$$"""####!!$!"##$"!"""$"$$!!"#"!#"$!!$#!"$#"""$#$!#"#!#$#$""""$$!#"!!$#"!!##!##$"!!""##$$#$$"$!"#$$$"$#$!""!#"$"#"!$$"!!#$##!##!$$!$"
@r4159
GTGTGCTCCTTATTTATACATANCGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATNGGAGGCCATCCTTCCATCATTCNAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGACTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGNTGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGNCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTGGTTACGAGCGACACTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCA
+
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
@r4160
NCAANAATAAAGGCCCCTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCNTTGCCGTCGTTCGTATTGCCCATTTATCGTCATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCACCGCTTGAATTGTCCACACCATTGATTGTTATCAATAGTCGTAGTCATACGGATAGTCCNGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTNTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTNCAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTCGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGANATAAGCGATTTAAGCTAAGAAAACGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGA
+
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
@r4161
GAGNATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAANAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATNTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGNTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCNTGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAANATCNGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGTTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCANGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAAT
+
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
@r4162
CGAGTTTGGAAAGCCAGTTGATCNTCAGGAGGTAATCTGGAACCGCGAACGNANCAGCAACTCACAAAACGGGATCGTGAAA
+
H692$2B#A9:E?%GAB"1E4$B&7HF06#,71(.E-@BG*999:5B!09%592?>/526!=+1",E1$(!%A3=,G-</7,
@r4163
CTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGNAATACTGATGCGCAGCGCCGCCAGCGCATAAACGNAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATG
+
#!'H*:%+/896#*?:8F#""EG-;E,BA-8:F:)@F=E/)8<<2.)4>:#G-->=CG19,79F<CC+?#DF#E#'A2H3%G2+??%2(45=C>F%45!#AB/GB<,6<A2:-AD@'A4E&HCG0D6D18>$6$A&&9G8'4D;*47H5$;"1?AD@B!FH5#.2?(G5H+<$'2C9$F85E(C<:<=7*?6"9<A@FE*E&D7D2'4$);-(2;>--,.2+4;F1:&ECG-@H<7(%2E%AD"(>E<=E3HH8522!A+,3'*=8@=4CD#/22A4;.G5%#:0B3@634#(5>$5E*E0B6F=95(77(>70*)-4D7&(<7($&&EC,"E>0&%;'@C>:(8C$AA,(!;(;9*%$!:"%.0B03B21?$A(9=3,*.F07:=HE8@DC'(%6319F8<"@5C>H;17AB3+
@r4164
TTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGNGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTAAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATT
+
/#/$:!?D9F:72<HH#8AA9+.:F-B<F>H!&G0";/"1*!1=8%<-+1.G92>1#;B$8:8&D:*@@@90)@@+CA)/$FG=$#1&)?6)B@!9;>34%*",>3A('A;G(>@G=!8+@&.3@*>#C//"FDE)4!0.'$'./":*8?8,#70,""H.F4<9B04;";6,:80!<+%+E94$&==;,@G46@85C3$B%@.>!#E"1%H
@r4165
GCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGTTCTCTTCCCACTCACTCCA
+
7@8=BB+*"7D5;(?5";/E"A/(H54FH?#5@1<.F8FA6F7@*82+HG>(.)C6#(>B/0:)D8<0:2#'?/%?G-6B,C5"8B-&@2)75C"75:983E.+-,G3'D!8.A#(*$-.H%'#3*=BB
@r4166
GTCTTGAGCAGGCCGTTGAAAACCTANCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAA
+
4))H2<-:9==-94A0G5#21<A*>:2>!!)C3<C2<$.261!>&&'GF+45D6F:A:$1#:$577!A52.AFAF*&(00&-C60)-+;?>.)*8A0.-0@&-:37589>9-A(!A<=@D,5<<,H55A253!GG538EC%F>*B-=37?3C9(6E/-6'A476*@C!)0'&A#.@(*95<#*2F">F=:;E/?+E,+A=@"8(#DAG1A>:->ED"CFEC%%#!%!&;46'-2(9:$%0104F52H&$4=2(.(49AG98#A>?'HG*"!8))*&(.B0$83&?G>;6+//E"F4.7.(#B=.D>1(C$BA7;.?-8,:,2-?EH/9&0D)-9C"@%%(C7:4+$2<@%$72#9/$0#+<
@r4167
TCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGNGTCCGGGTCTGNCTGTTCACCGCCAGCACACGACCACCGGTNCTGATACCGGCATAGTCATCANCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCTGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGC
+
&)75*29B86.8%.;*C,G!*FA-@4,%):(5FB!.C'7-#=5%D<:-?!G2G=#792;:#,)<*/3A.G:.,#6(6;G#1(5.)H,"30A@=G<'B.2!*"<;:*%A)"+FH*88>1G'8!G<?/2$8%.(9E"==C8E+./)E6D)?EH7-'=;?0--!':?2'+'(@!*0A2@4%,<(:.9C,6@"C74:1$-)@/:'E:0#"-B@)28*<=8HGF0C&F'?"-B//428,4+">C/F$D>**;*=8&=!(?"(0-GA#$!'@:;:)6/?1;;4*>D"$.47;=*(&2='6
@r4168
GCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGAAGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGANAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGT
+
E/99&"+7CC8A??%3.)=7A50+,"9H/.C>C1E&9="&!*',D33*EHA-<=17!D=20>&/9B>5C=F-G+9"14%3).4,B*"5;&GG#:%&A/2+F?3?F+2#B0(0/E1=H;D?@4?;9,+37B>HF9-C6;(,D)<(%C#D%=<F<5F3!548,$E&3E*$8A0:G&#G"F%"+4H$D0;6+977>A;@;=%FCDC*@D!@A$4":"'75?H+0"41.6,<?/729E(H(<'*2>-G'"..@*3;0#1*8*?-/!<@!;)+&C6
@r4169
CCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCAGTTATCCGTATCCTGAGCCGTCTGCANGTTCAGTGAGTCACCCGGCATCAGGTGNGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCNGCATACATCGCCTTCACAATGGCG
+
,;*@.*1=@'C$%>>A!2>92A;4<7-B'%#@+DF@&(#%<<,DEA#A,<3*?'5><.:9+0B1$%D$A@63??3;&;5!%C;1%!'1,!4:1(.$6;*,2<+:(E(4%#(5?0?(2/0@92)&/93+6HA/$0*/!1D?197+F.%G42F)7>DF1E%$+71<(2:-;(;)D*'#2C1.H%1%07DE=D97/9>?$)0H6/)8>E8#9.D:$C,8;2"H3'G9#E2:#0**D1B368:2=!A4?H1.B;@:8<7349<H;@7<9&,.(+D?E#>-4+D,F5
@r4170
NTAAAGGAAACGGCCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATCGCTTATATCTGGCNCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGNAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATCTACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGNGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACNACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCANTGGATGCAAGCTGCAATCGGNATGCATGGTTACGCCTGACGAAATGTTTCCTGTNATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTATACA
+
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
@r4171
NTACCCCCGTGCCTTATCCGGAGAGGATGAATGANGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGANACAGCGACGCAGGGNACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGTCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTG
+
!#*(!%(+*)!#%)&(*'$**+#%'#&&&%!(#')(%#+*&$++#$"*!&$*()!&)!'&)&#&++$#'($(&!#!+"%#&%%"!)*+%#!'$*##$&$)&$""*#&+#('"'+%('&*$!*#%%+%!$('%$*%%(!$'+*)$)")*"$'!$!$$'%("'#+&'$'#(*&$#%$*)+(!*("+'+$#"&(!(&!&&&&)!+!!+)&*&"'*$$$(*#$"&(*%!&'"($***$)"++#'($#$#((#)&"+$$"!$)!(#)$")+!+"&(%!#'!+""'+'("$+&+)"(%(#%)*+$&!"*$&"$*)"%'#(&+&"'+'*($#$&#'#""(*("%(&%))()!'&#+&$%&$)'(!!#
@r4172
NNGAGNCTGGNGNAACGATNNNCTCGATNNGANACNNNANGGNACTTTCNGNCAAANNTACCTCTGTCGAAGTTGAGTATTTTTGCTGNATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCNTTTTTTATTGNTCNGANTCGCAGCAACTTNTCGCGCCAATCGA
+
"'!$$'&#)(!"$"'%%'%##!$""$*)#%"((#'$#!$%*#'"&(%")"(*'*(*!#+(+(%'$)"%#*&)&*$%)$"%&!+(*%*(''"%"$!+)$!(!$$'("$%(&&#&)"*(&"#)!%)%#'%'%!*'$'%##"#&%(")##''%%)#(&"%&"$*'()*##$%"$&++++!*))(#'#'%+#'!')'*)!*($*((!)"$$&#&+*&('(*$*(%
@r4173
GAATAACGAGTNGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGTTTTCTCGCTGTAGGGGTACACGAGAACC
+
B5/(B&""C%,BG+&#4>%=8:28182,3238;9";%.--<87&6!86"B9462&*$C$*B"?0:7,8/$66F%7*1-#$C+::1/%&'.
@r4174
GTTATATATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTNCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCNAGAGGTAAAATAGNCAACACGCAGGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGG
+
A1E?@A&9<C*17-%F4/33<$54*?7-).3C10E182)=");(HF6>!>0?GA&9D,;FF,:.(,&#')$/%<<H$C"*0!<"D.F1+084D'@/7?%/>+D94#1E$82:-30%>&8<<?@"2)!6-3E;FE'7G8:EGH<0!=2@2C&H-(-#H=$>H#-7;FH.)<:1+;%H6E@/FB<?:F!,3H%05@1?H7;B>/77(F-E,B.)98?'&'4*/8C.4%6&04/,>B3/*$++>*4-C;B**H%0>CA-ACF%.<1;G>B:F:*<7F6;0,F=:"7G1:?+E8=%%%8;#<H"-32<70?AC510%H9%(,)#'*12@-F@11<77F#,*E((-&/F.54#6
@r4175
GGTCTCTCCNTTTTTACGAACATTAAGCGACTTACTCGATGCACNCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAANATTATCCGTCCGGATATTGAGACATNCGGTGAGAACTTAGGTGTTTTAACTNGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAANCCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACNTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTNCAGAAAGNACAACNATATAGAATATTAAGCTCGNCAGGTCAGTTATTTACCTACGACAGGANACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTCACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTANTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGNGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTNTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGNATGCCCGGCGAACTGGAGGCAGGAAGACAAACNCAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCAATTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTAT
+
%%;?F4"$+?97%0<%1>#"!G#4C@":922&*@7%D><%2&F62@6H,@!G199;'E'<'#:31FA!'<,7-C/#44'!&-*<:.>7-/F>!:G"0/>"EDEB6,)#D"DB$0.57H2H7689;17?&4&70.5G9F#/1>=<+,9438*D3:?+#5,3)FE9%#,@$#""G8G6B87()#:F?3-33A'/92.!F9B@1+H#8.A4C<!%7%H&/;E=<%G><!3?F!7BC@G1"A$/,FG8-=4"*=/0-B3015(FF,3!")*4<2@5>3F*A5&)?6>#*06(@'24D6754,A*"E(F4&%C$!0#?B'G*6"95@FD)>7DH141*)49%/E*4@0!!@2:B?9)@D$67G&'B4.13;E$2+.HC&G'6C1='9%&5-;@?-3'=FF1209&+5G0'",()@"H&C#84F.*&*1F@08*49CH$1/6D5,7.5-69BA-%D$+%>H,+9=&@@%3@@3&<(:02:A'!25"H;;>"B,4%G%91)*63*+;>.6)#5%?=5ED!#71+E""/H,#/1@#C!+69&)87$B'D:"G4=-)=.)18<?-023C)':):,C?0,;H2274<5,H5H8.@".,B3-A?;D-?"<AEGB<G2'72E99!!*76F60.700-4$&(1*"DA7=%"3+G;A1!5A1?7=C2@).@=$>&DAF56+#C2#(!:6819&@1#<%&+3=CCA/50#,$E*=(9(@*,B3!#-HF9="-;5D,A?GD1ED.0969D'>;H<4=:%E=)'G#@/'5(96(D7)%33!(!A+3B$FBEG!+(9H"5*+H6E=?G8""3%:8=:7!<-?!<.E*D-B3:<->4H.!09A/)HE$5>G"5<=D$:01&3A3-/H9%FH;#8C?)0#$*:5$C=>?#)013:<?+&C=(=A3#C<38<18CAF'F7DB:0&,4$5A?"G;.-&4C!@(.=4A@,*80C,-:/."G%+5'9?"7-*DH$;5C6=$;;@*!'4,%E;AD17F)E#54)*+FD1H/*DB:/>:'-&1%.!(,3&H&G7):)D67;1:9+'9!/#>D9!0/!-H*D3E.E(@F?813<?/@;G90E$7D)&(++%.0B">C8#B!>.(*28:.G-H-&4*+@7$7=/(?.?@4G4B:(:132&H,GG5-*;(G>F0:H0E">,<;:'3'<A?6AH!-#*10:@8"
@r4176
CACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGNGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGNAAATAATGGGTACTGTAAAAGCGGTGCCAG
+
D;A5''-5-9<$.6)?'?773$"(7*79D-C5B)6(B3%4$1-:$9=$GH+8H5.F6B%#A37@AD.-/-*(*C9!7EGF.4;91F@D-"**D'*6F!5&8GD9,BH60E.%EHE<,3C>0?CC9E$%BC?-88"E<"(#C!$(3<=-:)F.4$30>,6$'DGCGF$"(H)D"E8"C42+G#1<03)CHHGHB&?#1
@r4177
TTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGNTCATCTGGGCGTAATTCCGGGAAGGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCNGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTNNCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGNGTTCAAAAACGT
+
6:<2!D6&+E>"""7<%8?B;;*D5F=;3/B2H*62@1?=-)H3E!3=()743%2/!1).,25AD.#:7(C38)2#(3#,03E>HH+&CB1+!6FH*+9*&#<%$4#3&B%!.5+<(08C8,(5+"85CB"8/B7-8G.(9>-/E7A92>F$E*H7A7,'E<AA/,DC/9=:/$.3#H,81#GH/#!.%;HF82D2)A+C8=G4.:0==!+6(A>!@F>!F,%4%!1H3;-":A6E,46B:;C&5FA'1+)D68(G;"C3<@B!(09#+$?A%F+272#'17F;%/%&E1/G!/?>+.H:506+@2('A'0-#7,$B>:(/</'DE1=AB$4/.)=+(1?&($05)8$%@.6*<,>3&588,8.02!.B@,+.-+A&6DC0)$7,,?C3(72.:E95D@2#$(9D+<+22'B#@B(!G=8>?H.*6?134-8-?""@AD699-4)*"0!?%-F=:AG(/4+/.0+;;DED;17);D/;$<8H7H*2H6;C:/D4/F4&
@r4178
CACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATNGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGNCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGNCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTTCGCNGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACC
+
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
@r4179
CACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTNTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATNAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTNAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGNGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTNACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGG
+
-D1FC0<(*<'.87.=&6!$32=GD(F$=<'/!1'6AFH"24>"5,=5:D0/)E:(@(@D8C#GA;%=D*9;3H=!H%&%$3;.47&0EG%,+%B()+*139:GD63(04@0E*1A&BE7>%>A:''+;00'2?$15B@9#4>:CF-=B!H2:-==0/)9(:/1"'C&3@1@A0@#-=%!(+0F*3>@F"+;(E6$"=@8<HE-<DD0,#""@<$*HD3G2B2$%)>?&1$1HD)/""68)H*6.D7<%*:;C%8-!::H5F?*>5<0"DD5H2353;C/=3$$,,*1B#;079:2?B@71=!"%GE6B-#,*5+!GB=2F'$;H"->*E):9(>>(=,DHC*;'!D:A=)D%)D:A)3&5+;4(@6+(6B(%H".F?)$A*.>CG:!G.0,&1"G95#,+4GA!H86+&(=3+)=+9'(?FB2<:/61;DE-46!@+HA5.
@r4180
ATCAGTGGTGGNGCTCTCCAGAGTGNGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGNAACGCCGACGAGAGGAGCAGAAACAGACAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAATTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGANATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATCGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATAC
+
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
@r4181
GAACGCTCGNTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTNCACGAACCATATGTAAGTATTTCCTTAGATAACA
+
#G<%?78:>"'.?)B<*#3*<)6>F"%/C!*<G,1AH6=%=5<5C,!;34644,84-(A.67&;.C'?A)$;@7(C@H&3H4-G*E&<EE)<-236'5680%GF@<#8/3,.5!%9+637.6(17:?!E)HC*G*%7*.7'))G71"9H83:0E104)"C!F?#B7A!F#.B&03/,E<&1$5BH%C=/7&D,#BH,9AA$F('=43)<%DG*445D".$6)AH(D6"E#5"/G/E8&3;A6<HBF9C#2(@(!86D>F<B%2"9BHGD&:;).$0=BA+FD,&E$+(-@%D.
@r4182
GGNGAGCCNGNAGANNATACTAGCNNNTTCANCTGNNATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCNTACTCAAGAGTTCTTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGNTCTCAATTTCAGGATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCAT
+
*(&*"&&("*""&*%"#%'(&!%)&"&#&*)&(%#&+'!!'$'(*'"*'+$'")$&'"!'+&**'%"(!#)!+($&+(("#)'+&+))&+#*!+$*(%"&(++'((#*'")%))")'#"('*)+!$&!#*$$(*()!!!$&!')*&*#(%#+%&$(+'"%!"+&%'!*!&*+%&"#)++')'&('#)+('"""!!+##(!&'###%#$*&("+#(#'*)%"""*$("#$$'$#%$+!#$&##+)!&&*"!*"$%!*($$&+&(#$&+#!*%+!'%##'
@r4183
TGCGCGGCTCCGTGCCGCCAAAGCCGNCCGGCACTGACTGGTCGCAGTACNGGCCGATGACATACAGCGCCCATATATNCACATNCGCCGCACCAAGACGTT
+
E<C.F*3)G:21@<&52D3B-*=.G!<?=)+*=@:HH8$4E'BDA-=*"DEF@@2+D>=F'/@+&!!#:1C-;%G%022'A)=#='03/95@9/?+7A$+%E
@r4184
TNATTGGGTACTGTGNGTTCAATGGTTGTAAAAACACCTNACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACNCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGTAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCGGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCAT
+
54)E7?8/E4-%4GF)1'B>'E7.3F;#=<G.1>>!7C-%G;HG?A2!E,8GGB2E?@DF!+(@&,(("$8A*/GB$B08G$621CE)8:)59:<C'A(6"(61G=F!9EA5&(=H:+?:;1'/#)(C"64,90)>G3F&&E=G:>G!(?5,C/>@C7E5<!)<34:%-*E,$=)D,>8<9CG$'D%E1HG!>C43=63HED!H#2%*E2=)D(@B6@9CG&4/<,"E'D$=4?H;<9(9>">5!)?&2376?*G="?,;-B65)*#$A4E&&27$6">++F3A&2"9,,*7,8069GH+"6-6/(!6G:3=75F,F;=)H@$A-DAH45:%@CB498!G,H'EG2#(B<B?:08
@r4185
TNNATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTNGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATA
+
%&!F*B4/$1;'22/B0$E19G'-4)5:3"5/%A<CF,;=%"!$?;B3!/7*:'B96#>C.=3*85,;E,<@0A-+2.HD(.0"A%12>>=H4$%A2886AF/3%62"*2DGB)27E7*5%;-&/AEDC<H$,=4E/C0'@+A51G)$"--31.4(F.'+%F;98E326*@F:=E#"10<A2D%E8"
@r4186
TTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCANCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCA
+
A8%/0%+-;9/<C'.&!F=!(&!E3HGBD@B><0(F,&("!8/5*)(>-;7@6,8.#,9D&-$,&(?9<%!*FE!=.(#/#)@G902?H+=?(93$&<4D3878*D92D:$1H7B;;G;.?#8F#5+<9GC(7,"&'"*+A!-79>?E9<6E3>EGA>0'-2BDG*F)+-E9"2$9?6$3!').;1.'(@:88-F-7EB#7"A:E5/HE''1%*A+:!C$8!4'CA$;@,D*(B&<F,D88F>.F,+9<6:"F.2$B#$A)$FC'*>
@r4187
TGTGCCATGANGGAGGATGATGCCCGGCCGGAGATGCTGCGTCGTCTTGAACTGATGGTGGAANAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAG
+
6--H19/AC##.:-HD#'<=B@G)1'-)7+5:F8&B*?9D!&'-9->>GD,=B1+9$BE*HD:C5F'+,8F%;,658-&,-E7-/C)0$1H%0*9*%'0>8@2BDA:D?F.B)C
@r4188
GTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTGT
+
A.F$CE:%#A!@?-/GG<;?%C0(8F!><?E&<4;;B<'H*!.5:.F;$5.
@r4189
TATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAAAAGCAACGGGCAAAACGGGCCGCCATTGNTGCGAAAAGCCGGGG
+
+#%(!%'"#%'%)%(+#++#'&!+&$#$((&&)%*!+'"'&)$#")")&)+%%"$##')!+"!"!**+!&*")($$&%%"*"+#&#)''#'%+#!
@r4190
TGNCGTGTTCGTAANTGNACTGCTGAGCTGCACTATCCCTTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCGGAATTTTTTGCACGTATTG
+
$%"&*&&$'$)$)!$()&%+'&*!$++$'+"%#$&+*#&$#($+#%&*'!$')%)#$"('!'(%$')))!#!+%+))#('#'&'"+*")'(!#$!+)+#+$*#$""%%%*&)%$%(($+**'
@r4191
CTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAACTGAGTATGAGTNCCCTGTTTTTTCTCNTGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAAGCTTTACCAAAGGTGATGCGGAGAGTTGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTA
+
@"3A0<#E!D1*%A>C4-,A#0F51'<2/+>"*FHB'=E6;G;%&*51%HC4>.2)D.!4/88A$+E/DHG3-:9.0DDD.8'/25-G!B&"47H")#A,<0-@E%6:?3-9*H&G&=<(:G@2'$%.A@0:!+A3@!+;A'4G13G'05(@G4G#.0B%'#)%)699F=.<HD(#496H+2-F7(1($+FGC-(-#(:4@0.+D/(5%;'F0/&:""?*28"0;,<#46=FE.:?F:
@r4192
GAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGNCGGAAACNGATGGCGCTGT
+
,H7/)'1F+!H$G1)-+?0FB42#)6+'52H//?70:2#<?B9!;G;8%*0!,"58@
@r4193
GANCNATCNTANNNNNTNNCGNNNNNANAAGNTNNNGANGTNNACNCCAAGNCNGNNTNNNATNTTGNTGTTANNNNCNCTTNNTNNGNCNATGNCGGGCNGGNNANGNNTNAANCCCNCNANNNGGGTGCACGTNGTTNNTNNNGNTTNTGNANGTGTNNACTTTCCTCNGAGAANTTTGNNNNNGACNTANGNTCNNNCNNAGGNAANTTNAACGNTNGNAACNAGTGCNGNTANCNCAGNGNNAGNGNCCAANANTTNTANNGGTNNNNNNANNTNNTGNTNNGNCNTNNNNCAANNNGNNTGGGTCNANTTNNTANAANATNNNATGNACNACCNTNAGAGNNNANCNNNGNCNNANNNNNNANTNAGCCNNNTTANTNNTTNNNNANAGNGAANGGNNNANNNGNNNCGTNGTGTTNNNGCANCTNTCTGCCACGCNCTTTCANGGAGNNNNTNTNNATNNGNNNNNNNCGNCANANCTNCNNATNCATNCAGGAGNGACGNTTNCAANGGCTNNGTTTNNNNTANGNGGT
+
$#!!""$!$""!!!$"$!!$!#!#!#"$!$""$$"""#$!$"$"$"$!$$!#$"$"#"!#!#!##!!#$"!!$#$"##""$$!$#$"""""$"$""$####$$!"#"!!!#!!#$""##$"$#$###"""#$$!!$$$#!!!##!!!"#"$#!!!"$$$"!"$"#$!!"#!$#$$!"$!$$""!##"##$"$"#!!!""$$$"$$#!#""!!!#$"#$##!#"!$"##"!$"$"$$"$!$""##$!!""#!"""#"#!!$$"$"#""$""!!"!"$$#"#!""#$!#!""##"##$$##"!##"""$#$#"$#$$!!##!$"$""!"!!#!""#"$"!##$!$$!#"$#$#!"!$#!"!$##"#"#"$#"#!$$"#"$$$!#!""#!!""$#$!$!$#!$$##"#$#$#!$$"!"!"$$##"##$"""$""!##$#$$#"!"$#$$$"#$!$"!#$!"#$"!"#!""!$!!$!#"$""$#""$#""!"$#!#"$##$$$$$#"#$!#$"!$"""###""##$"##!##$$""""#"
@r4194
CCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATCACCGCAATTNATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATANGTTTTCCATCTAAAAATTNGTAGTATTGAANTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTCTCAAGTACTAATAAGCCGATAGATAGCCATGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACANACATTCACT
+
?E;03*E(,(64'/&%G!8=:/D;9B"2/>-6<#E-5G*/";-8>3E9$$0;#*:%:4ABCD%;4E$@$G1@<AA";",1(-.3.#7B4%=$)++!>,H>9#(<4A!)7F@!#G8E'/?$C(&G8>@G%$(-<H$81?8CH*'64A+9*&G7=8A"F&1F0E>.:#?3+A6/)D3.HE<>'$1$C,%<<?&*G#';G.7+A%/++912;.06=G!+G0/9&F/9+5->3)39=3-16C.H!'"/B.+'.@#97(?.#,@:16F@3@&?<?!2CA-=#3*H*0+;G83G#A%:)-1#G5EA*50A"D;:;38BC!"389&BC73))8;%-:./)0,9/6F*)?-0F3<(H+3&'@&4!)4!&<'+>16G.!"/@8@;"926H:/3H89'GA>%#."+6=5-+C.9?#9D.>>.'>808G1?%137DH2F0(!*=0&6&#.')5D'$@,/*'-:'.&>?
@r4195
NCGNCGTTCCNGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCGGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGC
+
&=$&C'2$A62)H/:*035E8.-:H*1B=1GD;!3=.+':B?%HE-147+1EHC9$.>"&").B%-478'C@@=/$,<D*E!&16E"2AFHEF?&.!.A%)%;E'C15E,9H.E0@6!G=#:&#@19";$38,(A;1ADB9FBG"@=@)A.#B3(=6*(8G'AD1D@+A"8!=?
@r4196
TAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCCTCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTAAA
+
=,&:4G5)G6$F-0.?"FB*F)'H8F?816HE<'63B&:/B);D#!"8&<<;@3G/DE@-@2";H-C1FD5<E&;#FD1E1.(/?#.='6CB?C;7,"5G&50BB
@r4197
NACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATATCGCCGCAGCGGCCTGAATGGCTG
+
",ADD>*&'"68/-@%;(D)(,<D'677?&G-F&>F?(B@?9DB+3%).F4D3*E<'E9"5$87*F1AH?76;##<"B<90:E;1(+E($?>!#$0A+1
@r4198
NNNNNTCAATGCGCTNTNCGNTGCTGCGGTATGAGCCGGGTCACTG
+
$%$"*'')%*)**!!"'$)$##%"$+")#*$+&(%*!!"+%*''&$
@r4199
TTACNGTCACCGCCAGTTAATNCGGAGAGTCAGCGATGTTCCCGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCGCTGATGAAACGGCAGGCAGANCAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTNATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGNGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGG
+
F@B:=*""A<3CFA=53&;#169"/<)B."F@.A7G.>C,%544)8@B(8(8+<6&A&:E:E%;A*D@)+G")3FH$1A:"5?9<#2*G-?.+0=2H4?&B+H%7(FD&"$D""%;+(9H369#/&'-0.4D#$G'*A;5%&>75F37,F2>)5%#/1?$E.047,C,?!)?B&7>2:B%D;-04H264FED>0;)@=?GE5/>!*)//9$!,297,*9?8#<#*%G(3H&!339'1;E,HAE%-AB094?-,-4-,22B87;H9&*/&C47!3')23D>*F5!@,"4?C-*)/)20280#%$H7D8HB<)8"DH$E+0E-FEB1F+=!A3,1'%',F:;#7,/G9H$9?2-+6,F'"88A"AC<!?:4%<9:DH$@'A'HD,+D-/?5C/43**36DH9*34@0'&9%<+D9E$.D@7)1C36
@r4200
GGNTATGGNGNTNCCAGNGANCATGNCTNNANAGNANNTNNNCCNCGGNTACCNTNTGGNNCCCTGANANNGNNNNNNCCGACNNANTNNGANNACACNNCCNTTTANNNGNGTNNNTNNACGANTANNNGNNNCANNCNNNCANNCNTNTGNAGNAANGANCCNCNNNANAGNGNNCNGNGNNGNACGNNNNACTNGNNNNANNGNCTGCTNCTCNGNNNNNATNAGANANTTGNNCNNNGNNANNNNNNANNNGGGGNTGCTNANCNGAGNNGTNTTGTGGTNCCACNACTTNNNTNNCCCNNGNTAAGNGNNGTNTNNNTANNGAGNGNTACNNCGGGNGNCANNNNGANGCGATATNANCTNNNAANNNNCGNCGCTNCANNNACNNTNCNNCNNTTCCTAGTNTTGGCNNNNCNTTTCNTNTNNGTCNTANATGNNANNACTCNGGCCNTANCGNNTATNNNNGNNNNNNNTGATNGGCCTTNNNNNNNNNNGTACTNACNNCCNNNNNTCNNAGANNGATTCGNNNACGCCNGCNNGCNNAAANNCNNGGNGNGNCNNACNNNGNNCCNNCAGNGGNNNCGANTANNNGNNGANANGANTGNNCNNCCANGAGCGGGCANATANCGNCNNGCNNNNACCNTNNNANNCCGNTNTANANAAANNNTNTGNNCNNCGCNGCCNANTGNGTNNNCNCGCCNNAAANANGNNNCNTCANNNNNNCATGCTAANTNGGNNTGGCGGG
+
!"!$"#$!!""!$!$#"!$$#"$$#"!"$""!$""$!!#"!""#!###""""!#"#$#$"!!"#$#$#$$$$##!$$$$""!$$$$#$#$$$!$##"$!!"$$"!$!$$$"!###!!$"$####!$"""!""#"$$!!$$#!$#"""##$$!#!$!$$#"$$$#!#"#!$!""""!#"!"$#"!"""""#"$!#!#####"!""###"""##$""#$$!"!"!$$#"#"$#"!#$!"!!!!"$$$"#$!"!#$"!#$!!!#$##"#$#!!!$$"!$#$#$$"$#!#"$##"#$$$###"""$!"""""""!!!!$"$!!!#$""$""!#"#!!$"#"#""$$$"$#""!"$#"#!$!$!"#$!#$$""$$!$"#"#"#!#!!$$!!$"""!#!$$!#!#$$"#"$$"!$"!#"$#!"!"$#"!#!"#"$#""#!!#!#$$##!!$$""!!#$"$"!$!$$#!"$#"$!!#"$##$$$$$"#""$$"$$#"$"#!"!"$$#$$"$#"!$""$!#!$$"!""""""#"!!##"!!$!$"###"!$!$"!$#!#""#"$#"$!$"!#$$#"!#""$"!"#$""#!#"!"#!!$"##!"!##$"!"$#!$"#""###$##"$"""!#$$"#!""#"!###!$!#"#!"""!"#!$#"#"$"#!"$!"!$"!#$"#!#!!#"!##$"!#!"!"""!"#$!##$"$#!$!#!"$"#$"!!!#"$#$$"$!!$"""!$!$##$!#"!#$$#$#!#
@r4201
GAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGANGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACNTTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTNTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGNCACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTNAATGCGAACTCCGNGACGCTCAGTAATGTGACGATAGCTGAAAACTGNACGATNAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTCTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCNTCCNTTTGATCGCCAGATAGTGGTGCTTCCGCTGA
+
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
@r4202
NTNCNGANNATGACCAGGTAAAATTTTCTGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACNTTCACCNATAAATTCATTAGTTCCG
+
"*%(!(&&'*#$*+"$+!#!%$&*$))&%!#'%)#+%#"&"#+**%%)()*#"&(##+&+%)%"$+)!+"#!&)$*+*+*!+$*%'$%'+)+"&"%"'+!#($"##$&())##&"!+!!%&%*)&$)(&*'+($+*")#*&$)#%'((!$&)*$"$)+)%%#*)+*'%*$&"&+''++)$"')!"*)%(*%)%)&(&$"$""&#&$)$"*!$+*+*&""$%#)''*("""'#*)#%(#)"*(!#$!!)!&"&
@r4203
TAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACNTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCNTTCGCGAGTTTTGAATCGTTCACGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGA
+
>GE<$=-(*,C0".AF12@:B'H0;:='@>HC>F-CGB'4(C+%-;=3@HH/?.0!"4*5;2C<)349#9*BE>?F,2>%A.0&F(,6+<%!D-;F>%*+25998;;*7>2D*/#8?E:=;*?@3HEG(;A,2EC<0=D+A,.H-F-!A<89ECH?C4;7;B?.?->1/DE<(?@=#EDA%>3:D+.&H(.0#7+'<>F5'@C#+2/8!G-$84E17(@%:+;?,8#B.*2-78>"@B<F4F?9E#$<%.?0*:B-2>DG@1A&D>?-$:C;(-F
@r4204
GCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGACCCTTTTCAGCCTGNCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATANCGNGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACC
+
FE;G@1H0$3B-G8F1#*(GDE8<?/H:5+G7G-F84F<(H4=),DG93%.<-/B88-)$;<1@,49<7#/0(;B7:#(+(4D;>.$#+<@70H9&%C!2FH53&2-*0"@B435"!."(@H/>3,,0C(0#.>>-F)(<7G;'H,F-A#2F6D)E%/2'&"6+B-5E<G6D=39456(1E7C@>;=4#(:H7E86&2(5",9>5)=#F"-6/,G571:=@G6"1=!*A252,*3D8#(=D)5,(.01%&"0%(0#!CH..4(:!6F!H59C>>H7
@r4205
AACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTANGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCGATGAAACGGNTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGNAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATAGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAG
+
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
@r4206
CGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGNAAAACTGGGTGACC
+
&#)./6<');-!*'AD9)D&28/&&$0G&&!0(!753,B#!19;G;:B4"B$.E/G-A+H:B7)>:6(/'%G6E+@?,B&<0+!*<(09G"5F
@r4207
GACCACCGTTCCGCCGACCAGACTCTGCATATCTTACGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCA
+
95@HEC>1(4=F%B.A+E!B''&E8*=6E*"%@!>$',F&@84=/"C,8@DDH)%7B2G(F$9-6F49A"AF!@A@/5GDB*7F2#%#101A;4&>)!=1+B9A&8A#:D:<HA5E:?GD&8$G:1G48#"=(83')F3D5H7A''#!,A<-F)G4%H=,.4!/,#<7AG-6<(=$BH)$>@7**)@7!,"/>;5:@?1=71F6'HD"F!'B53='89*(.=511D&D%*<<0$0?G#20>G%%D:=!H@@(G+H?0,E6/7"&;#+),C$8:<<B9(:F6&!
@r4208
TNCTGCGGNCAGGNNNNNCNTGATANANNNNGGCGNAGACAGCNCGGTNGNNNNNNCNGANNNNCNTNCAAANNTGGACGGNNNNTCNNNCTCTANNNCNTNANATNCTTNACCCGAGGNNCNNGNCCAAACNNGANCGNCNGCTNNNGNCNNNNCTTACGATNTCNTTNNNACNNNNTTNNNTNANCANCGNTNANCTTAGNNGAANANGCAANTTGNNNNNNNNNGNNANANCCGACNNANGNNNTNGTTCCNAGNTNTTCNNNCNNAGNNNNNGTNGNNANNTCNNNCNNCNTNNGNNNNCNTNNNAGNTGNNNNNNATCGAANTCCNGNTANNNTTTCTNTNNCCGANNCCGANTNNNNGTANNGCTNNGNNNNNNTCTNNGGNGCGTNNGACNTTNNCNGNACNAAGCTNCTNNNCNTNACTANNNNCNTNTATGNNCNNTNNCGNNTNGNNNNTGNNGCCTAGTGGNCAGGNATGNAAGCNATTGANNNGNGNTGNCTNTNNAGAAANNNNNNNATNACANACNATANNTANCNGACTNNNANANNGTNTNCANCANTTNNCTCATNNANTNNTAGACANACNACNNCATTGAANTNTNNGCNANNTNTNNNNNNNNGNANNANCNNTNNNGAAGAANNAANGCANAAAAGNNNNCNNGNCTNNNNANANNNANNNNGNNNCCANCGNNNNNGTNNGCANGNNAGNANNNNAGNCGNTNANGTNNAAGACNTCNNNCAGCNNCATNGGANCNNNTTNTCCGNGCNTGANNGNCNCCNGNGGTNATNNTNNGAANCNNNNNAANACCTNNNNANNAN
+
"#!!#$$$$$#!!$#$#$"!"#"!##!!!""$$"$##"###$!"$"#""$$!"""""#$#!"!#$##!!$"""$#"$"!"$!!!"$$!$$$!"!""#"$$$!$"!!$#!"!"$"#"!#$"#$##""#$#$$"##$$$!$"#$$$$""!"#$#"!!#"!"##!$!$##!"$""$$$"$""#$$"!#$!$$!#!$!!"!"$""$!#"!!"$#!!##$$#"!"!!"#"!!!#"$!$!#$$$##!$!!#""#!!!#"##$##"!#$"!$##"!##"!$#$##!!""#$$#$"!"!!$##!#$#!!!!"##!#"$$"##!"!!#!#!##$$#""$""$#"!!$""!"#$##!#$$$#!"#"##$#$#!$!#"#$$!$""#""!!!#""#$#$$!$"##!!"!"!"$!#!$#$$$""!#$!$"""!$!#"#$$#!!#$""!"!"""#$"#"#!$!#""#$"!#!#$#!"!""$"#$$#"#"$"#"#"$!#$$#!!$"$""!$###$#!$#!$!!"!$$#"!$#$$"!$$"!$"#!!#$""!"$#$!"#$"$$$!!#"#"!!$$!!$#!!"!!"#"#$#!"!""!$$#!"##!!$!!!"#"#"$$##!""#"#$$"##!"$$!$####"!$"$"$#!##$$#$!!#$$#$"!##!$"$"!#!#"!!#!$$"""!##$$#""##$$##"!#"##!"#$"$$"$##!!$!#""#"$#"""!$"""!#!!$!####"$!!!!!$$$"$$#!!##$$"##$!$!$#$#!$#"$#$##$!#####"!"#!#!$!!##$#!"$##!!!!!$$#!!#!"$"!"$!"#$!"##!#""
@r4209
GTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCNCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAANCAAAAACAGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGNTATTTTTGATNTGACCGAAGCGCAGCAGCTGACTGCTGAAGANCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCATTTCGGATCGAAAACGATGATATTCACCACACCTCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGNCGCCGGACTGCGTGATGTTATTCTCCTCACTNCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATAGTGTATTTGCCCTTAAGCNCGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGGCAGATTCTGCGGANCTTCATCCGGCANGCGACGCAGGGNCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACNTCACCGG
+
+7.7>5;>1!"63%F+1B3*.D!%=C>:>$<5&+"9,%='F1?!:%:;A?AG>-E%%)76#40-+)?-$*)4*;A<H<?B/CCE5,C#"7%E-*)A>3C-E')A+$;<.!C'1%@9;>?2E2F0E"##F$;&:'@A067#;2,8*5".8:8!#5>'-$$92)A?@,#()<"D3'C+-G-*98@+)-6.)4(+>90F#%C($?/@13<"F.0BH#9-*(-*4(=FGDH2)2("&*H#'<4)BG-+7@4B*6=)32(F-E='#-)/8:)2@E,/!,6022,+@?23&6-@=#(0?D,6G9=%0-3%?;:*=9?)6'38;#E$G=,7)25%2!/=G%!.:=:-"/:)':GB6<%D'3$1?1%!!#>.>41"D5%7(='5*.,*/(52;727!=7#FE%5BA=;<6FC9=&)E&/8,'8+,+;/F>1!HH%4$EG/@-;/E>28/$.C?E)1!&'6%=>"E:<%6@#/(A=,-$"<@67G)#%1&5A;,%==8!!(?($2D<E8HF1!94A@!-;(:D49FG21<@37'<95G*+$5;;7G.F.+F<:!%.$./@0D-92B=D/:!?0$+D".!80F2/*>!"83"!E0=/5:!E-6.02D1).;:7-BF)28:"F4EF//&#3<!,('32>)6%&6(#*D;-DH::$'CG21+:%!9&*,5B%?07CD!<1,*83+=%,=.C!!<CFB"2)E->.;C*:7.-GE$#.9!6G4+(0&<<,A"B7B9,,=*8C928A<746&5D63D8$:!2%"HA9C93=+4%55D5"%-B@<2;%*=:#F@0&C5H$>8.D2*1%F73/@)%B<8>*D4</55F99%&.8F'9E=09282!*7"C>F!-20(/4/0=$!)&,2F'F++;@'<C1")8)@%)&FE/+/*(G%#&G7#:("A!-(4C=?
@r4210
TGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGAT
+
>&%*D7-1()B%C"&9A1-:+:G9&?)9A8!4ACA'2&?#)."?49!@6+;&&'*@B18H6=--2(1#+A,@G53A>:GD.549<<5AD41?59.H=<,5"&=.7:46C;4<<=4*=$:;;G)6+6&FF232(?)(<&727'EDA9HB+=4CB69%6
@r4211
CCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTATGTCCGTGTGAACCAATACTGAAAGAATGG
+
.E(E%3&E4=-D,"A:.//B+6.7%3*;GB%5C0:,)40#4>=A4=6F-%E(&>&!E84?/(==,B4F+48;.5#5!86G8F+6'AD)@;42ABG%3742D)<G'>&&>(30=CC</";DDF2AC$.9E39,6.6.:/)-71"=A6(!$5EG49:E02905/3;#!!254(;A52G00FA+8$.#G10+0&F2188>5:B=!;+1.05=G5B0H.$5G;&(E@.(&(=6=#=;'8+/5+9;C(B$<'+61>@?A/5*E>)>=)'G8!8@DAG#!.<&4A((@H!<"@B10%:C0'/
@r4212
GCGCCACACTCTGGCTGATGGANGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACNCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCNCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCNTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTNTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGNAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTC
+
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
@r4213
CCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTATTCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGCCCCCAAGGTATNCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCC
+
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
@r4214
TGATGGAGCAGATGAAGATGATCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGATTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTCGATTGGTGAAATTGCCGCGTATTACNCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCNGGATACGGATAACGGCTACTCCGT
+
37/-B3B33+,+(56D0EF<7>B")E#<D(@%'-?:5<=+*4<<F;-9"3;<C':>%:<!5H;5/G>7:9)$<&1E'H<F65>D7;H@'9H/!"()@?F+=5C#640==#@&'GD8%6E,0@B0F40BAD+(9A224CF12G3G$CA96:'-H<")!+((5=B@/7GD"BA=955G3#7?!%><)9A@A>:3!0H>>2C1B!E.D(CE.15>=1B@/D9%A(<>F*$?6$@9,27286$*DFH093B:%G%<3&">76-(EFA0>",58$D6-B9*9B;'?:A6<&@G@&5E4(/!G-
@r4215
NAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAANATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCANCGCCGTCAGTGTCG
+
%%+$$&'''*($(')**++'$((*"!(&'!'&''%!'+$)*&*$&!$$(%"+%()+"$$$)#)%($+"&#$"!#&($&%"+)*"(%$)!)&"$&'*+$&!+%!&"'#+'#"
@r4216
CATCCGGACGNTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTT
+
B6+@/9CA1<&89&:;&("C&;449)=#E,.401A%<B-)GH'3#>7HB+25
@r4217
CTTGCCGNCNNTNCTCTGANCGATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACGCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGACTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTNTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCNTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTNAATCCTCGACGGTGCTGCCGGTGCGGCNATCCGGAACGATACCGACGCCGGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCNTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTTACCAGCCGCTGCCCTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCTGCACCTGTTATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCNTCTTTTTCCGGCACATGTTGAACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGNCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCNTCTGCGNCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAANCAGNCACAGCGCGGCGCGGCGTGCCTGCCCCCGGCTGGTACAGCCAANGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCANTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCNGGCATCACCACATTACTGCGGTTATAGGTCCACATTATATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTNTGGTCAGGTACGCATTACAGGTGANGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATNTATCCACATCCGCCGCACCAAGACGTTNCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAA
+
$*&'#&'"$!"&!%*"*"!#&"+++"$%!+"'))$%""$)!"$)(*%""$"$%!!+#)))!!$"&)'&)!%%*)$)+*"$'+*'&&*'"""$'''&+%)+$#'!&!$)#(*))+!"!'&+$*&*$%%('*"&%')"#(#$)%&)$$#%#+*(""&!"("'&+()'!+"*+)+*"!'%'*')'+##$*"!!((&"&'&+""'%&+$%&)&(+*#"%))""%'$'$'*)&''#&)")"%*$(&!"#$$+$+)*%"$%()"$!'")(+$'(%*'"(%**)"+!+%)&&')(+$#$$*#!*(#**+&!++$**+"$"+')(%)#%**#%&#"#'&%$**)!++''*&+%$('%"")$!!"+"'$%!"!%#'&$((*#$&#(+)"""*%'"!##(%++*'!$!)$)+#((+&"'#)(((")'%%#&(#"$'!*"!*&&%)!(#%&$$&*$++**)"))($$%'$$')(+"%&%+*#%&)$%'$'#*#+*+%+!!##'%'!'*$++')!*)!)&'%'(")'*#'%*+!(+*+")('%#*)"%%!$"!#(%!#((%(%)#$&)"*!)((!((#&#$%&$$")%'!!)%'""*'$($+%%#!"%#&""('"")((("*"'('#((&*$""'$+##*!)"!"')"'!'(&)*%*$*&!($))&(!!%("+#!)'#$*$$%#+!')"*&+#!'%%+&&#&&&"!%**++*"#%+*!#)(*(!"*!+&$*$%*++&*++("$&#$'$%"$#&*$*'!+#+"'%%+"%%$+*(#(%!#''##)*+**"#$&)#((+'#()!#&"'$$!%%)#'+*+$$)*+#$++*!(#&'!$%$&$!&(%!"'!%(%$%!*"%#*)"'+&%##'"*!%'$'('+!$%(#$+*)&*%$(#!"'(!%'$"(%)&%*+"*&()())'*#''%"+!+&(+%&("!!+"*'($$*#&#&$%'#)!!&#"($&$)%+!)%(!%"#*#%+*%%'!&!&"$)$!+(#*)*$#)"%%)*#%!$*")(%"%!+*(#%#)$+)'"#')$"+(&$(&*'$+($)#&#!%""+!%%$$$"'+$**"#)+)#**&"*+#!$(+#($)'$&(('&'+"$'+"%%("&#)%$!*"&"&'&(*$+!+("'+"!"$&+('+'!")*'%#')'+&'"*#&*)))!#("%&"!"!*"!'$%!)$&*)()!$&(!+'$"*(%)%()+$%*#')%**(#$!'!!(&*$"!"%($)#!*"*!(&#!$%"(%'('!(%)'&*$"&%'#&**'*#"*'*%%$!+**)')'%%!*%&!$&&!$)'*%(%*)$%$)*!!%+)))&(!"%#(#&#*&$&&%&)&(&(""(+!(+#*#&(!*%++"'"++*++((*'%#&"+!#+'"&+(%'"#'(#%+(!#%(#'&*&%)&$&$""$#$'"&)'*$*!)%#*+$++%$#'""%"'%*("&'*&%%#&*#%$'"&"%"$+&!($'!#(#!%)'%"'+%$("%+#%!'+#+*"$('!($$'#$'!*$(*"%))*!%##(!+$#)**+'%%%%$"$''*)*!+#()"$#+"$&"*!'!!(+(++*(*"'$(#&#"&$*#()#(#*$%*(&*&"*($*#")$!)+%#&!*%$##$#)(#%'*%#&'$)$!""%'!(+$%*"*+"###!+$+(+'###!'%!*&)(&($*"!'$)$%'$#%&*$)$$'%$+(&%(*!+(%)&+(+'(+&(**$%'$(##(!$!**+'&!**+)%%%(!""+&#&*'")#)(*%!*)+$'&($"%%#!(+$!%')!&$%'+"$#)"+*(&*(**"((!$)(*(%"%"&(($"!!))!%"&!')&+()&!#%&++('&$*((%*%"&&*
@r4218
GAAGTATATTAATGAGCAGTNCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCG
+
G%?H370=2';(4E%4B6D09%"D,1GHC8E,)#:#?:"6%!1'A5(?;2:?7D</G-/4()>E2/;4$;,?)(2'$.C+4$1!5#3C!3,1!.<'1<H=(9@.D':6F:EHD<)*CHA,8(?;D%15)5&%6516:%5C0@<&"@85810*)79/6.B$?>E0A:;;#=C'-G*G3B>H.5*GC++GF120"A861C#&)'13!0*7:5.-6"-'?2G9>3GD*G5?=(=.G"-A96,#?.B@3B'<5@&<3(01)@%$E%0E&C@<19EG-#3D:?<!&B&8/@)!)"(FG1FF7A=F$-!D>0=4ED-:3&H4FE%+@?B'$820D*+ED;"*
@r4219
CGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTNCTGCAGGCTCGCCAGCAGCGCACT
+
B@/!6?;#<,&H'H(3+<9G@1AB!+B;*<A?C>;HA("8@B"2'/<54H$==,@&")4=81E0-7.6+E8C>GF00G,<8AC-#9>$#+?)5F&#.H6-72C:;+7<$B#<>=%'?<:C
@r4220
NNNAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATANAGGCATTCGGTACAGNGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGNAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGTACGTCAGCATATNTGCTCTGGCNAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGNATTACGTTTTCATGGATACAGGTTGTNAACATCCAATGACATATCGGTNTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGNTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATANTCAGACGCGAATGCATGTTCTGAAGCCATTTATCAATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCNTCACCAAAGACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGTGGCCAAAGCCAAAGCNTNGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACNTGCCTGCAANGATGAGGAGGGATTGCAGCCTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGNAGCTGCATGATGCGANGTTATCGGTGCGG
+
!%(+'!%&&%)"!")#+"($+)%%*"(%*))*$*%!#+(#$*!!'$+*#*+('#'"!$"&+!)#&)("#&!''##&$!(%$$"'!'($*"++&$#&"#&#+%!#&&%&*#)+#+&$$!*$%*&#'((&($*$#%%$*!'%(+'+++%##"'+'('%$%($&)&+$!"'$%#$(+!"'()!'((#(%+)&*!#"(&'*"$$%&#+!#)%*(#)!"#%!+*)&($$+($'"'$!!&#$)#"(*#**$+!$*(**+"*&'()&)%#+*++*&%(%(("+*+$"#&(%))&#"'&%!"'*##"#+'*!#"+&*%&'"'%+(*#'('+*#)"++%'%#*&'*)#%%$*"*'"#%*('$(&*&!)+)+)()!"!"+!(!!*!##))#"!#&*($&+%$%&*$#!"$)+##*+*$!)!$'&'%&+$%)$*((!$%"#$()'))"%!$!($))%"!$'&#&&***"+%+"%'+&($!+!'!%$'#'*&&+*+'%#!*#!'%%"'+%$#'+##&'&***%'*!+'+%)*(+)+'#$!$'#$!!"!+'(%"*#)''%("*(+(+("!('"&"%%#"!+'%$**&+"$(%#'))("#'))$"#+(''#*%*"&$$"+(*+"'&&#&*(&*!%!'$'*%!&'!%&'(%$!!+&')$'((*'+%&*)*%+$+%(%'"$()++'+$!)*$%#$!)"!"#$*!$*#%()+(%$'(%*%!)&!+!**""%+&)%&#%&*($(#")+)$''%"#+%(+$"*#)%&&)(%"$!"!&%&#!!%%+%)&!)')!+!*&*!+)))##"*'&&#)"&#*(%*)$!*'*)"$&$+("))$*!"(!##&!&%$$)($$)&#+)$$+!(++%!$#*%+'#'+")*''(*%!(#(**'++'%!!)"(%#%&'$+)+"((*$$('#"$*"!%!&+")#(**!+%)*++*$)(%&#!*$+!$%)*"'+#()"!%'#!##(%$"&#+!%!*$#"%++*'!#'&'#"+!)!!%$&&$#*"&+$($'(%+('%+'"&!('%#+&!#%"&&!'*)%+)++'"!'*+$(
@r4221
TTATCGCCCGCCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTNTGCTCGATATGGATACGCCCGGCGGGATGGTGGCGGGGGCATTNGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCNCCCTGNCAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTTGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGTAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGA
+
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
@r4222
CAGGCTACATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGG
+
F&12@7D;@)4'5G&1!&?2+7&F17)ED&&5-G9%'C6!@&1)!!;$G//!0F.!:
@r4223
ATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAANAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGNAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGATTACCTTACNGAAATCGGTACGGATACCGNGAACGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGNGGA
+
@,'FAB8/9DC5$1*7%H2?@E(H>2>!7-E%*#++8F:,A;G?$!*+%H*$:C<"D)C(*@;&&C'&!>+C.(>>C(+5:'=3/D3%4"GB(-2.D7!:(=<6#3+61)C;0+(:#?9@-@,'"(!F(.50EF42"97H797?H&:/@91-;BB"?0D0G=@!7!)F/&:(190@60,#.-$::F;.&D-&;=8<A0+6$C#,F,793@<'B<05HHD70?$1H>6<6
@r4224
TCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAATCACGCGTGACCCCAC
+
-(=*;AE<0F9$%-1"/GB=(3(#@#)H@/*/F=#BC;H9'0B$/><1%GG?"0#;BA.!B91>?1>>>-$B%;=42(#10
@r4225
CCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTACGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCNGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTT
+
3!A181?;9.5C7E@C@>12$>*E(?'"*BA8)>?$@$B$@2?>?/@G0,H837'=AH2#(%6.+)A=3#4?,!=(=>ECF5481A1;2ED=5%HH01:0/&;-A@)*G(.G*F*H38797+1!->==BAF@G&($AC94=<<G:;+?F:-ADEC&
@r4226
TAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTANTAATCTGGTGAAGTTTTACCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACNCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCCGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGNCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCANGCATTCCGATTGCAGCTTGCATCCATTGCNTCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCTCATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATATTGGATTGCGGTAGTAAAGAGTGTGCCTGTCTNTTAACCACATCAGGCNCG
+
%+%!(*)'+'!&%#$)$#)%(''*)+)%#++*)!"!*+'%%"!!*"$'!("%'(#)!"+"'!$)'!#$"#')*!#**+)*)#'+%+*')$(&!#)!%&&!!"#('$$+(*$+!*"*'$$$*)%'&%#)%**)!$+#""+&"(%%+(+'(+!*(!%&"%"&&*#*!&"&%$!#"(#$*"&%*''((('!+++%'('(!!)'&&#'#'&*"!*$%#+%'!#%*(&&*#'%(""#+$++$&&(())$+"#((&#$!"#(#!&#)+"%"("%$)+!("'(!!*!'"("$#*&+'%*'))+"'(('"%%**(%#$)&)*&%#&)#(*!!*$++*()#"+$)!(%('+($%)*#)#%"*'"*$#'""%'&%'''$*!!++)#)'!*+)'%))'"'$*%"&)$+()&$##%$"(&*+)$&%$($%*$)+!*%#!$+!*$'+*)*%$*%###+'$!#&#')!)!(+!+&'+""$+(&+'"#(%$!+*)'!&(*&()&((#*#()!(%+")'&!#%(""#"!+%(#&)(*&+'&'%"+"#%')')%"%&'''(+$+#&!+&%"*'##+(*'+++&*&*('*&()!)*)*$#%&+)!!)#+#%&"'!&)%!)('##)+""&&''+(%('#%$$*+*("!#()(!')&%)*%&&+(&#)#!!&*!%(#*#'$)"#*"*#)$)&*)""'#%)%'*$")%&%##%!'*#"')+#'#)**'"")"&+
@r4227
NNCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATA
+
!%C"B0?$@H(19$(%@%8(-!3?+/D)/<0BH-&.+A4C'$C0%8((4E).=:),AB8!F>(@96%#=2D6B*(8?;CED!'3@D36@/)1,;1)0:@4:1DG@.D!,3004-9HGA!,=E*;6:$.H?0/+?(&5@DEE)?8#3/.9(H>!.7!(;<7F'>'+"B6H8(!*64:8$@0)@2/0;&2$H$/$!7@''.9H6@;*?894((E:7?-+)1-*3.B910B!-$)9C,//C9!4";5C9EF4?-A@H07B0+.AFE),>=#C'!G;(91?+18B<=..EC"
@r4228
CTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACAC
+
8A';6$19'7;E:BF#(*.F'1?71+?E%?D,;#1+D!<"2*9(A.@%9C+
@r4229
GTNTTGCCCTGAAACTGGCGCGTNAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCNTGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACNGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAGG
+
&$%'+*%'))+#+$!)++")#''*'')*!(#+%%+(&&+(")")+*!!$*%!*"$#$$#*&)'*'&"''%&"('$)"#&*$'%"%+($!#)%((*(*"$$!*#*"''!$!+((%!%'%*#"'+!&&#!$%+"+'#(#)%$%'*#(&()+)(*(()!+#!(&++')%%''#")*%+#%#&+!$*#((#*'$+&#%%#'"#&%+"*#"&!((")*$+"($$)+(*&#+*)(*&*'+(''"!%*#&(&!%!%!*!%"'!(')!+
@r4230
NNNNGNGGNTTTACCGCATACCAATAACGCTTCACTCGANGCGTTTTTCGTTATNTATAAATAAGGAGCACACCATGCAATATGCCGTTGCAGGGTGGCCTGNTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTNGATCAGCCAGGAGTCCCCAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCNTGAAGCCGTCGACGCTTATAAAAAATGGATATNAATACTGAAACTGAGATCAAGCNAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCCCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGNCATGAAAAAAGGCCTGCCTCAGCAGCTGTTTGAATCNCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGNTGGCTGGGAAGCTGGCTNAACGTGTCGGCNTGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCNTTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAAACAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCNGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGNACAATGAATCCTGTACATGCCGGNTTTACGGCANGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCANTCAAAACTCGCGAAGGCAGAGAA
+
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
@r4231
ACAAGANACTCTGACANTACATGAGCAAAATTAAAGCAAT
+
%!$'%'*$((*""*&#%+*!)&!("!'()#%)$&#!"#')
@r4232
AGGGAAACTGCGTGTTGAACTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGANTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAANGAGTTAGAGTCTGAGCAAAAAGATTGNGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTANGTAGATGAAGGTATAGATANAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATACCCGTTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGA
+
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
@r4233
AACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGCTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATC
+
0H#?D%(83GF2G.#.'%,$?<&/36/5';'3$$54$?@A$1#H9HD$;H1F;8F,%<.F22%BF6/?81C@GH2;&&<HFD.2=E?A:/!#!.0)/03!(A;+
@r4234
AGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCA
+
49E5706G$%>'4()096-49G5D$F-3?A*D(0C4+DG%(1$E90&CF,24(B3/2.@@;&<#,EC26B%<)=,!D;@$6?C/%+80G?;.91<FCDA<!'F
@r4235
TTTTTGTCCGTGGAATGAACAATGGTAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTANCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGANTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTANTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCNGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGG
+
7'+$='>#2<*D4..2F.B!H-<:#08-/*4,/F2EHBD=;)3<2HB?>=;6D"3E4!3:.<;1'9?,?F!G>:>A33,0>,=%#10'%7A*&<A!$8@=G,/A9A>6G?D31E71,-=3@6$;8E#>8!3F+;G3HG6/'1;&,:+<BD=82G(#+;152051?<1F.E&5@,:0?17E)4)@>6//03#<9B6#1:E,9E5C2;C59'9)*5%@$>DH0:',1D5B-B8)5/7?(C5*,.C<@+H,&BCB#F8"/#!4B@0A4)-)AEEC";).+:B7<(<E74'9.A>-6A&'."+".?;<=7:21G%A?#?&#1G926DA$B",3%%2'6<717A(D35-4"@>'FF9*;B;;*6"@F,073%DA523/H+4CB+@A$;,?F528E:%(@"9=A463A4%&3(C/>?9*H9.;?'36@.,D?0*".;+6)!/60'<?/)&0?*2(>!D;#;3"C5",DD':G#87*4=)'GD#@=+9
@r4236
CTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCNACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAG
+
4/.@-BF+5<8A2!2BC:6;:/';'7#7(;FF$((A(#)B.&'+),*B7&<17073<'$:2GB;#9%"/<*%%B3,56C1.27*D@=!9B'=F404;'-8)2H#:A$$92:.@!1.BCH<B1-:691/:9*6<#+$5@4H%.>926D:AB7B+<C&C),55,)/3FA3E8&/(>6$%C50
@r4237
ACCACAGACCAGCTGCAGANCAAAACGCTCTGGTCGTCATACAC
+
8&3)@(37%F0E$*>.C468.<4G%%1D?>9E"%D17*=*7@$!
@r4238
GGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGANGTCCGCCTGCTGGTTCNGATACAACGTAACGGTGGCTGGGTGACGGAAGAAGACNTCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCNTCGATGTGAAACAGTGCTACCCGAACGCGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTNGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCNAGTACTGCGACCAGTCANTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGACCGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATANCCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAA
+
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
@r4239
NTNAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCANAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACAGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGNTAA
+
#$+)#!++"'!%%''!&*("$)%+(!!)$%*"%(++$!"+*$$!!"$!'&*!""!#&'$%&#%&""$'"()*+'!+('&$)+((!$*!&("#"+$)!%)#!"('#(*&$%&'$!&*(#!!&+$#"!('"!)+'("'&$'%&%%%$%'''&#"%$!('$#&*#*+)'"&+&*#)%!$&)#+')'$"%(%%"%+*)%&"&)%(++"""'#%!('!+%+(!&*&'"#%&&&+""+"
@r4240
CCGGGNTTTTGTAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAANACAGTAATCGACGC
+
)($$'"+*'+"%&!+%(+'%%'"*'!!''&$%$$%+!$#+$#"'*$&$++%%##$#+()$*+*)***$%*'"
@r4241
TGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGNAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGNTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGNTTCCAAA
+
<+E*+1C:#G1?47''0G>.$H&"&2<6C9/5.?,+E<#>163/55C581/A7<=1/6"@&61;!@)5/:8+C><$#<*0"?;3.$,539.92-AH8A;?6?0-6-0@)$),&%@9%;?%6-6"88'8,*9#')D+30=1='!.">6<-9:$5+HD144***C(.8EDC!E@5(<E)C-(64(2%=&'7C-8&%@E:)0GEE'HD1ED006B-;'E,"ADH.*->H&AA4$60F@>-%23;"!?H*79)F1=/A?(5!5HH<254"'
@r4242
GCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCNGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATNGATCNAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAAT
+
%#2(@(HF(:;%4F,DC&7;93"%B#=AE6A:F8190;H8>EE58EC'"%$;7G&03<D6!B=(D'%C+2#<1&=*@4<5/C.3<.=(,H17HH7672#8F+A8$C1.+&&*H@&E#@DA";$7?/'EF"5!=7<<:%?!E#@*=.<E'#:"/$ED.2*(7"F;F5:@+=80'7F!"+,5.61A*9F.G0B,.*7F-7'=687-)B/<!F,B@$-30?*E)&%HC09C$119H!G):0:6!B)B31:#
@r4243
AAAATCCAGGTAACCTTCCGNANCNTCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCNCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTC
+
<@D;7E7!6"F*?;B<6/3@@,18.H:A#;0@1='"G%*%9)7%9A%*FA!$GD#H#BC.475'7/"D+H.0$GBC.>H=H$65;@<G>B/$G3C&#$=/)?(18EE(2"5A8!H!H%,6EE0A:4;'"2E+9;$0'&A"(<<(2G0<B+*77)>$2*>3(95&:C'D)'!7:=47FA*8/D%B&%@/585AE$DG!=$6#B44G*'=)=)8",E+#CC%BE4@98$#?.";'%(#,$>:6G5++37+4A63!*'(D,78G+;?D:8>@3=:8D@$51</9*+F.<.>@##
@r4244
GCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCNGTCAGATTGAGGGTGCAGCCAGTGAATCCCCGCATTTTATGC
+
@E52G55>B<D?5/%8!,<"C&#':>/3E2;(,?12-GH;F:C<-4.<(#?*9+"(B?.512@/.?<BB!)7?5:F74;G<<=H$$&<@9:D-1>D!FB:2!+:-949/'C1+6&HED*20")0F(2*3@%8!816&5-:B")%D'G/&=*G'%D,$;8%
@r4245
TCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGNGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGTGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTGATAACCGACCCCAACGATGAATCCGTCAGTAC
+
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
@r4246
GNCTGGCAGNNNTCATATTTTTTATCTTTGCTCACCNGTTCGATNATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGACATNAAAGA
+
#%&))()'($!##+&")!%#'%)*%**+*+(%#$*!"!)&'()+(($(')+#"&#&#+#$*#*+*)!(%"&*'()"#(&+$%""!")*!(("($!%''!+"+(%'%*'*+$)"''+'*
@r4247
ATAACATATTTTTTATCTTTGCTCACCAGTTCGNTGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCNCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTA
+
7#?(*E9,,/*+DD"2B>0E'!+:$/&4-<BF8@9C,6G1-*0+829?<BA1&%8C0*7@E7791=7(-*1#!.HF*:1C1G9.6&A%%.2(&B(F4.9'00FE.G7255.%8#$75.4770),$G.9');2-B6BH*;47>*"A8"1<*C><'4B)21=DC0@81.#+D$A(%&66A1=@-3(1$G50C;-H#"2.4A"6H:B$AG;;7$B4&-./<:HC#CG"@.)A'%H:E=BAD+)&''CF%(##F2&<5'+@9+3480GF;190/0&)A0=7H7*@;+5:G<1!@%#&>/:&!1:#A==B"F6.B5%
@r4248
GGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCNGTTCGGTGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAANCGAGANTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTGCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCANTCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGCCATCAATTTTTTCGTAATAGCGNATCTCNTTCACTCCATCCGCGATGAACCATGAGAACGTCNTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTCATTTCCGTATGNTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTNGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATCGTTTGATTCGATTTCGTNTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCNGCAGTTG
+
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
@r4249
GTAAATCCCGTCTCTCAGGAGGGCGANTGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCACCGACGGAGGGCGAGAACGCCAGCGCGGNGCAGCCGGACGTGAACGCGCAGATCACTGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACNGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAANGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGNGCGCAGTGACACTGCGCTGGATCGTCTGATG
+
%@7H6#%/./>E(,:$+"+G/D@&D;B'2>B+D+06#A2$33:,:79-$6&*1<)..=5'AGA45,2,09H#,4+=(&G:5&#H"A?B:(HE8:.G7668>B%D"?%'&7",*9$:96EHA=>5%#%D,765G5#F9*A5'!?.+?#@"%?G=H5&-C'&-.%2?7C<:@$'"746"=E"!#>&>E=/GC$@C:,3=70/1*+F@=%4"1BA=51+E@,'D=@+5;?5)3@@8!',5',(;8=H.&$E1.8)0:A+47+G)146065!5@+G,A58#,-;-A9$$!$%:$2&D9&*7'=EEC3CAGE195)6+>0=H%.C9#C4(3E+#D+&G7G..G@4:7F(
@r4250
AAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTNGTTTTTTGCCGNTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTNATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGAC
+
38.#4FH-1@E>&*#-!74=31F=D=".$6%D=&3@*==D'?<>9E;7"4<+-1?$1,5=D0@'5A#0;:B%:78+>$/!/"*<D>5C#@/4$/G(F;-D!E$6()'9.004G!GC8@H!@.8@+"/-H/;EB&*E+E=D;8D;,1>0%(%?.*;($62%F$H"&)3(4
@r4251
ATTNACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCGTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGNATTGGTTGNGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAA
+
@#5927?,(G(1F-!H;;"/6A$C>4>/%-H>!'6F!')!($0+'15%C4-/53+9+/*:EDEH,-&'@-7G&.6':/0-?$;4$)@,@5-A,?=7>"#%F5@!:3E#39E77C#+<H&&!A+$@H42G!A?8@5@+=@0!)8=E<?=*556B<@.)C*/GHEC#CCC2D/CC/+#D<C-G>DG.GA.@-65/;2)89&$'")@%).4.#+>20>2G:268(>4?5"'1'%D,1$F..//,&:,79=*3%%(1)C"#&-"-!%;>$5*%>E!.(9-%F4@'/(8=BEBDC95<$?--C4B!-!%:CEF"(.%=;?'%BHH1C%&C82:0D-$)E46F'"%-C>/1
@r4252
AACNNGAGNCCNCTNNCGNGNNCAANNAAACNNAGCANACNN
+
"!$"$"$!!"$$""$!#$#$""#$"#$$#$#!!##""##$"#
@r4253
NTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATNAAATTAAGGGTTACTATATGTTGCAGTTTAGTGTTATTGAAAGANGCGGGTATTCCTGCAGTAGAAAAAAATAAGG
+
''%*+("'*&'(%!++#&#%%&*%#!($"'&#)$'#++()%)!(%!$'#%&&"#'))$'#!%$&'('%$$"'%'&"**%)$''&&+"'#"#(!+$)(+#"!'*#"$%!!)*'""$%*&$&"**"!'%$&++$+!**#!$%"$#"#"($+&!%&)!&$&*&(!+'""
@r4254
GCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGANGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTNCGACGGATTCCTGTCACCCTTTGAGGTG
+
"D3<6+7=,8?9>F0G8?@G'3'F#CED>'409/<B(1(65#;6<.?E."'G1''C?($29CB%/'7+@/(B<5#?68"H5C@'62=64+3/%C:,'A7=B$.66#$'?5'DE!7?:'(:"0#'E6,2BD7%@6G6-(F:%=$&-2*F!1B,DA@:B$0!7?B*?HE(#3:!<,*!3)6*AG84'@030E&(7
@r4255
NTNTGNNAGCTGTNCTTNTNNGGTTTGACAGNNCGTNNTNCAGNGNTCANGCNNANNTNANANANNCAAAANGTNNTAANGNNNCTNTNNNGTTACCGACGNNTCNNGANNNCNTNANCNTTNNNCAACCNNAGNCTNCGCNGATTNCTTCNNNNANNCCNTAGNATNNTGCGGCGACNNNNNGNNNCNNTANNAAAGACCGCGTNNANNCNGNNGGNNNCTAAANNTTNNNTNACACNGNATGNNANTTNTNCGTGNGNTGTNTATNNCGNNATCNGNAGTCNNNANAGTNCNNGNNNANNGC
+
$$#$"!!!!"##"##"#$$#!#"#$$#!##!!#$"!#!!#"!$!"!$"$"#$!!$$#$!"$!$$#!"!#""#$!"$#!"$#!!$!$!$###$"$$$$#$#$""$##"""!$$$$#""!###$#!#"#"""!##!!!#!!"$"$$$$#!$"!####""!$$!#"#!!""!!$"##$$"$$!$!"""!"##!$#""##"$$"$#"$#$#"#$$!$$$!$$#!!##""#"#$"$#$$#!$$!$#!""""""#$#"##!#$!##$####!#!!"$#!"$"!!"#$"!$!!#!$"$!"!$$$#$"!!"$
@r4256
TTNGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAATTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCT
+
$%+"#"*!*%$$#()"$#"(("$+)#$!($$&&$'$!%$!$%+$"#(%+&)!&%#(#%$'$%%%+"($!"*'+$*'"
@r4257
TCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCNTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAAC
+
1EC"@7/9CCB->.9?>-*:71BGG+H>?%*58'&$?A-+G"(/+8#4$,H&->#*%:<8%G)/++&/=?5*2!&H<'"$EAE:6:2@;,F4)B/F/+96"4=G>"C$%G/.'2)F=89'1491(8?62#!%H9<)518@$(C=6!F?'7/2@-<.=!1&,6;"C4EF?<:H<!1-C#3=GA66@+?GB+(.)#66F3;$H*
@r4258
CAGTTTGATGAGTATAGAAATGGATCCACNCGTTATTCTCGGACGAATGTTCAGTAAT
+
5(>#C%#G%;#8@#1B$"563.%A>=94-%9'6-E?;7E&@"=!!H#)@/-!@.CA1/
@r4259
AATNTCNNTGACCCATCCTGNCGANGATATCCNCGTAGGCGCAATCACTNTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAAAGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTNAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGACGGTGGCGAAAGCAGAAGCAGATGAGAAAAACCAGGTATGACAACCACGNAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTANGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGAATTGCCCGTCAGGCTCATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGNAGCACCGCGAAACGGTAACGCTGAT
+
!#%"#*!'(*&&!"')*'%#"*)&!'$+**&!%$$!('(#"!)!)"$+*$'")$%+*$"!)*((&)))(+%%%"%'(!!"+)*(($#!(&)+')'%$'(!'"%%+#"'!'!#+(*)*#$'&)%"')#)&*#(&&#)"+*'$#%!)#$&!!%*"'+#'&!&!!!')""'())!#+')$&(&&&*)'%&&*#'(%+&($'%'#'&))$#')%"""+!!+('$&!"+')"$&%%+#%+!##"+"')%%)$'#&)%"&$$")"#*#&(*'$+&#%$#!)*(%)#)+*+*#!"!#*#'"#*+*)%(""(&)$&$$(($+*!$$&!*!$#*"*(#&*#!"%!&)+!)+%%$!!!%""#)!$%*#($*!+)&*&&+(%'*++)+%$%++(&)&*+!+(+$#+*#$*&*"%(!*&%!++*)#*$&+&)+!*&'%#&*&+%#('#!+$*($!#++%"(#&(&''!"+&**+**$*$!&#$&&#"%'!&+))%#()&*(&#$'#&!&(!!*!"#)'("*'*)'#$$"'!'#&#$#!(''&#)%!')(($!*&*($*!(!+(("()''$!'"'&%%(%+&''$%$(&#+'$
@r4260
NTGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCATATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGNNCCTGTCNGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGTAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTNTATCTCTGCGAGCATAATGCCTG
+
$$&+#'"(')'%"**""(!"%%$&#+%+)!(+**%(&###"('+*%!"(+!+)'&&*+###%*$&+!'!+"#*'#")"("+*)))"'")**&%%*('''#)##++"(*($%%(+$%+(!)($#+(&#&)$#%"%)"*#)#*&)+#!+##$(&"%&!+(+"(+&(&&"$$#''*')""''%*+**"(#*%)!'$*"%+%%#)))'+"+$%&+""*)+&$)+''%(++)'##&%$'*''!"'%"!!$%!"*#!(#'(&*)%##"(&)*)'"++)*%!&"!)$$*##'*&)!("()%'$$+)$"&)'
@r4261
GGANACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATNTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGNCGTGCATTGCGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGANGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCNATATGGTAAAGAA
+
5'+3),?26+08*A90C9D@":4'8B&;*=#@F<1.!:@<$,*4;>)&C!<*,@3#="H45):C0+-A5DB)C4A7BAF#!0F2$;,B-)HH?E)2($>E3>4B0@75B><+39HG@H,%?;%22*<E33#%(F-6FB/B(B.E.=53+%GD<,F#;C%@=*D!E5F"3!39GC2=0<=0!(E)28H%;))(=,:/$'72/47$0$0>B;/0G=1GE''?#(,C314G7$#*@(3#."-7BAECEF>.HB(.&G/C-04"=".2H6@F"38<(7.*F5*624&*>+B:%091>B;%*'#C7EA8.1$/%#-+1
@r4262
TACAGTATTATGTAGTCTGTNTTTTATGCAAAATCTAATTTAATATATTGATATT
+
;A2H-0:E#F!63?.<2C;'&/0$C>&-B0/%#6:/D.$C"8,H8**(=$C91@0
@r4263
TCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCT
+
FD7(>#(;/69(;+(':9(*C@;>,2"">H4)/<2D)%@'+0<"+
@r4264
TTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGNCACCAGGCCATGTTGTTGCTCTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTANTGCCGCGTCTGCNGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCG
+
++)+$++#"*))$&#&&+&#$$!!#&+!&%()!")*&+(&$&*#!"!+!$*"'%$("&")$')%&%')!)#%&$$(+$%&*#&)%+'")!'('!)$&#&)&&&'+*%!#+%*$)*!$)!$$!*'*(**"#&)##"$+'(+'$%$!(#&+#(#(()'!!'+*&')%)%(%((")!'""!&#*#(&%)
@r4265
ATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAA
+
@<:G(/7#B#3+*+91C*1.,4>$7AC4EB5%F+!4B0::?G4F,&?:
@r4266
ACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGANGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGNAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATNCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGNTGCAGATAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTNTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCCGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCA
+
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
@r4267
GCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTNATCGCTTTATTACCATNCTCAGTTGATGCTGCAGCGCNTAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCCGGATTTTCACCACATNAATGGGG
+
*A5-,)%0C+%/-:CF*E-@,9H=(,B*H.A")2,$9#&;!.D750&>@977E:HG<B-CG4(;5<"&>7+*"F$?3-!-(<0+?!2;.@7ED:3>=H=9E!>A-)"?G>4H0H.G8<438>46/D&0D3(*=GG<6:&9>8G@*)8G87*=H1())-@($0)F@"0@!:()7@"!D**5-@G5'D)3;=
@r4268
GGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCCTGAAAGCAGTGNGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGACAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTNATGATGGCGCGGCGAACGAGGCGGTACANGTGTNCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTNCGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTA
+
E<7D?+84'5F6@GH*:C//!&%.0</GEG5HG:B74?$+/.%C-#A-'9DF(FBFB"/!FGH@;-.5$<BC,/=9')1/8H0/)(;E%@B6(C-$34,B<42'=468A#"/5#?<&#A$.DAG!+GB;;$#,;F18(A'$2!4"C/42.#HD0+2@6/57&-@.>!C17)<"?4E/)F=31'.&"%+56%&,DC?<*'5%41A39#&6GC<(8.:G(.7EG6,A&$%=2-.77,::D2=3G0E;(=?#=7<+?)1?HE>=%9::'=B81C2!27#A)%3%3!+CF@$0:BG?H<>D)H.8->=4"E=D?4*E4@>&4#>(4(610$H?%C*,3C>$4=(.A<@"@1;2<G(B#!:*,$"42''FA>8D<-.+F+E=""0+4":>C,("A;//A'A,HE*80>0//&'%=;663C<BC@7E"#'D0)&=8H6"9653H5=F&FF$8@5'B.)#'*1'767??AE/.H:0<?$-G-*':;&1;:>*&"-)3">&53
@r4269
TTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCA
+
)>.;">5408(?%90H3;'3@2!!+)(>>1#:5/+G@F%%D(>)FB=17.8+9-1;=HH122(&DH#/*7;072$B@%*17%&:5G-=#$"F>1%!:02%0,)C$64@1*G#,=4/G@(F?($H4'2(-B,8
@r4270
CTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCTGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTG
+
F-<>92/9/B+8+B5E=)#&0'7)7D6$+8H>7G'D(F+?/6A>B!$3+9>&E275.$3H=BG"+.&6/!(B<G!F5BAC?G#.F;A9.2%=C)9D:FC&=$?D.G*>;@;H+.G5G4=*&844,H?51"HE;3<7.(=A-.4,@%==H(1>3';7>>8+@6D%/<:+9.E38=8A26=;EF38FCA?;CHEDE4$)E-G53>+9?&4913C?(''B,&,C=FF/%%"2/
@r4271
GCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTGAT
+
4;;.,:H)3;7)/9DG-C!))>F<3DHE4)7GBB1'2-./*2=B""-.*
@r4272
TACACGCATCCTGCTGGTTGNCTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAAGAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGANAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTGGCGTTCCTGAATGGTTACTACGATTGGTTNGGTTGGGTCTGGGATTTGCTGTACTGCGTGA
+
E?6>B+,D00<-);#7#,'#6G297A<D7-B?5/7G675464FG.1%46)C6'H>"F$'26(B01$!+"0?794?735-'+C=/3G<,1024&(&=$B20%#<H7-<B.'>;A)349998/,)G)G+*0,G*(DDB5H4?(&&+!44,>D*E)6:)F+'DD#9C!6:B."'1(#+%!&/G%GG@DH15%5"886D%./3@A($7/,?@F#*:BH,17'1C82?GFD3@E@#/+>5<C1?,/D03'+C+8>#7>&.E55//?9
@r4273
ACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCNCACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTNCACCTTCCGCACGGGCCGNAGTGACTGTCACCNCAAGTGCGGCAAAGACAGCAANGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTCTAGTAAAACGCCCGTTCCCGGACGAACCTCTGTAACANACTCAGACCACGCTGATGCCCAGCGCCTGTTTCNTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCANGTCAACAATACGGGAGAACACCTG
+
&7;)&=.$'9.F:2>)%ED?H2F&7+%;#<#6!/?&:!4#7"DE%G1063)>&F@&),)85'%H;&3>3+4!.3,4H,,>C<B0E+5&BD!+!)/?@+8%('HH15?5?.*(,/"F%%EB,8-+7H0A'B7++GA1@$8?,@GA"5?3'-EHG@1!:/>&%3/*<(/48.:/;G=.!/FH(*5%+G@1.;,&<B6;E.=#)21D(@6#H02@&@@648&$!/)==&$:$="*$0/4*-$@',=:&0GD;59%5A#:/%&@9-099;DF@FG*.+E)29#E;/2=/H*;9F7>C?%!7@E7/,<42BE0EF,7#"81*FAC.!4A/34E9:9'+$%C3(9A)!C831D#/87<&'8($;$6:G)A,+:>)%)*&H#5<+(+5H1.E'2H&=(2?198E+=##0A,H60<*%&?7$*>&03*=/$<2A&+<8'66;GAH
@r4274
GCGATNGCCNGAGNNAGATNTAGGNGATCTNANCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAANCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCNTTGCGGCGGCACCAGGCACCCCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCT
+
"*!#(#))$()#)%#$'*)!)(%%!%'(#$"'#(&))"++)%'(#*(!!+!$&"+)+"++*!%%)*(*)("*''&$!%&)'*)!))""$!$(%""+*&'"%(#&$"+(#(!+$"&#"$*"'+*+'#'$'''**%'('"#")((!"&!"$#'#!*#!!&$'*"#!"&$*#'&*$(&#'&'(%"$"'#*#*""#'&*$%)$")+#*##*(#$)*
@r4275
AGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCTCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCNTTTTGCCCGTTNCTGCTGTGCGAATTTNTCCGCCTGCTGCGCCAGCGCGTTCAGGCTCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCC
+
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
@r4276
AGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTGTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCA
+
>*8!B902B!?3-39>,4@.*2B$2)@,<(HB:>2=F:>G>>5AB3<'*=$7BDAG&5+A3/F#<*2H#BF.H--''*B?2!/?HHG=;@:@*4B56,&GDDH#.'0%,/;A*=&(8-<E*2$0+'#CGA$,,7H+:>#)G;D)<"#DG-549'HB#845G"'C.0-@@302$/*<%)(".42"G)7'#8>@#6;7/D.."+%A;*'<)A2(A-.,<@'1HD5#).1;CG2"$''D7EH/&<FD*A60!1/E$97%#+8-9'2D6(;1<(;"@D@,?D4+*&9'-142A-/C9B7C&2/D!.!?23<'')BD)DE43/-B)%8G)(;>+51,H73<-!=6HD*4#@?6D>D@-9#CG/F51!G9A//%9(((,;@=.0-537E*5=D)A/$@@6A;%)G59#>6/#+@/GD%)E"&#'3##G<4D6E:8F7/@-,/FC=9!@2/B%10
@r4277
GGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCNCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAG
+
8$*(=G0<A42E(=G&B&%1$44A/":,4A%F7.9,97/-EA%G<:0+*:$9@".8)E%$-%B3<)=#+>!GC/)/2;:80
@r4278
CTGTTGCNGNNNNGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATNCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTNAATGCTCTTACCTGTTGTGCAGATTTAAACCGAAACAGTTATGCAGGCTNTAACTATTACCTGCGAACTGTTGCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTANGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCANAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGNGTGACCGCATTCAAAATGTTGTCTGCGATTGACT
+
$%'''('%%$"$!+'+!%%%%+")&"'(+%))&"%'!)*)%#""("$*!&)(#*!'$$%))($("+$$(%+''**$&)!(#$#($*#'+""!++)"$("()*#*&%"($$%&!)#%)')+*%!!"+)()!$&*++'+&+++*$)((+'$#*$!!++&&*!!+'"%"'!*!!"())'%!!)))"*"**%##*#'*&#+)"!'$("$!&&#+!*!")$%&*"!$$+"!&&&+%)!!$!&!+((&#+(++*$!#")"&&$&'$"'$*(()&"$%&&"%%&"*"!#''&$+#))*"*!"%&*$$'(&(&!$('&!(""*'*)*+#&!+*)&#!%#&'"++#')$'*"!'+'#!'+!%!'!$("$"'!'!("*#+"&"&$'*&$+**))**!$$((+#(#+%#$*%"'*#+$(*&+#(!+((!#)!)%#(!$+(##*&%$"$'(%()++"%'+(+)"(!**!"&*!"
@r4279
TTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCNGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTNCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTNGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGANACAGTTGTTGATTGAGTNTCNTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGAAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATNCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACATGCGCTGCAGNTCATGTNGTTGGCAAGCGCCCANACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGCCAGAACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGACAGTCAGGCTGTCGCCGGACACCGCATCCGTCNGGCTGCTGATCCCNAGCTGGCCTGCAAGCGCACACAAGAAAACCCGCGCNTAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGG
+
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
@r4280
TANNGCAGATNGTCAAAGACTGGATGAATACGAAAGGGGATACGGGAAAACGTAAAACCTTCNTAAACACCACGCTCGGTGAGACGTGGGAGGCNAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGNTGAGGGCCGGGTCAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAANACCTATACCCGCCGGAATGGNGCAGAAATGTCGATATCCCGTATCTGTTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCTGGTGATCCCCANAAGGGGCATCCGTCTACG
+
#$$!&##+*!%"'+$$"''(&$*"!"#($(&("#"(&"+$#))&!+*))%$*&+*!)!)#(%+##()(++)"$$(+(&($!!$!)%"+%'+%'''$'&!*"(")!!##$!*&#&%'(%'+!"$)'%%"&%"+"'&%(%#$)+))$+))!(*#''''*+%*)'#%$!'%(!#$#)%&*+)$#)&!&*"'")()&"$!%)&!')&(%&!(+*(())'#('&+"%!!''$+%!!+)'$%(*'")&)'%()+$%)$!*'''&*)"#()$#%+#+#+$*$"+$)+%)"($*&')&(**&%+!%+)+#'(++))%(%!+##&+%*+")&"$)'!+!*'#'+)'#%$(#'((*"#%$))%$%#(&+'(+'&*#+#&++)+&#!##$*&"+&"#$&&*(%)$"))"+'(%!''#))!$""*!(#!&#$$*$&%"$&"&#'%$)(*'&!&%(*%$"'+)+(&(%(+&!('$("$%##*"$(*""()!
@r4281
AACATCCCTCAAANTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTANAAAAGAAAAAAGAAAAGATTATTCGTCAGANCATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATNCTGCAATTCAGAGCG
+
?(54E812G0E->(/D%F<E-3C<2:/.7'G$DF%2;-.9/G745,!<.=+GA(&;1&'5.5++/$'@.H#D/D%H81!>49<"C?,HCA-*)D(6)0&C5&'1>D%*&81*D*"-:2))!81>E5:3F>"G<8H5>F.2*3B"=-$2F)4:@2&>8GA1<(7/(.G
@r4282
TGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGA
+
#9<#5.<#2DB4(5:.0(A:)G)F;H5?58+*">8F7&#D(.9D&G"0G&B*;D%+!6(CHE@;@+E7!)A;=H44A:<#H',*5(;*:C"@555)=,G'<*%5).AHC1".8H)5C-.@F1)2,.0=$1>)H:#-4GCD1F75!!!*92;6.#<&,=./>'"A4E$9!#9<DA4'-!*B>B(C"#C90?;%D(+'B3=,'9$G:@C;50.6">G))8"9,'E+A5#420E4=#).(D65@'?.F9$@412B2EHB=<$E8@B*,0(&)-.*(@$*B&6.B"/CA-=C/C4:,D"5!H2!#%,@.*.-:.(,CF?-EB;5GA100H+>.E!-+!"E8,3C=:%.7,HA+3/'??1"9$7#D?<-1='B."H,"DHD'@G/,?C/
@r4283
GATGGCTTAAAAAGCGTGNTGCTGANCAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATANCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGNCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTACGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCNCA
+
<+H)4)6'4"8B3.$C,/CA14.18>,+B0?$,%7?17)2BD=8,6@",&()DH+2F4?-%/)B0C05E,;**6G8;$101A)7H/>+"8&<C/'C*27.D$44H<B)C4-(DF%;D9G151H<G"@D)6&96*-,.4G7F-C.1!E0/$2@-6+(@D;!?/A+)&,7'@5H,@2,#EC+)AB2B/+;8B$)H9?+;3A(+2,900B-"=0HHF;"55<@FH&5%2-!GD<@@832E?,G94"@>8%2($.8&F,>7(>#F
@r4284
TTATCAGCCAGCANAGAATTAAGGANAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATANAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCG
+
A*H"F<./631'30G%23-G,<.,)452)$!-E9*3C-*D+)#*G8-=#FC6AFFB,E15CGD.C=<-;<#",#9""72#06)?=B9;"'&/D.0%>/+?(.<B;(6#B?9E+$54AF'GFF$G+@*?#-%0A@9B$6$$66B?"0E"AF,-1DA0)
@r4285
CGCCGNGCAGANATCGCTGAGCACATCCCACGCCTTACGCTG
+
?3F''"',#,E=1-2!7*<=>F+)=AEF;2G!6<8#59-75F
@r4286
TCGCCNTGAGAAACTCGCNGGNNCTGNGTGCGTCTTCNACAGTAAANTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTNTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGT
+
#*)'($$!'*)#%(!%$$$*)"&!#&"$#%(''!%&&%'+!"!"')+""))&)&#*+$#%#)'"(*&'%!)*+&#)&#&)$*+*'+'&'(&!'%%*$"#'"(&"%%(****(+()*'(!%!)!+(+(#
@r4287
NCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATANAATCATTATTTGATTTCAATTNTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCNGACTTATGCCCGAGAAGATGNTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGANTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGNGTTTCCTTCATTG
+
!-"/)1;7/G00?B%/#884D=<@=+>-7E$?57D!*DC"DDD0:/65(71!$'1B,*H863E$<3*)">.2$*AB$B.-D8:&>,5/<3A,)B12B07%">79'D<3E:)!A&+9?02/G*-@24-!,<$48B1(C(4?E<$H1=#D'@=,6++;-%F$=2;>AGF0$/#9-/297A)4F/&F19=F3FGH:F<0,.+)<.3#9E98AB6%BAD!G@>,A.@AH#+#5<G04A;-BA/'3C?/3G#8B<A#'(@08<,**"9<.90='>#D-*,9+F>/@92.3:(F826#:+!%/&#%,A(/5'')<2!!$+1<B99G*0G-))60./")G!219"/D+>&!+?*)'>>C)HB,>:C2+>D)&",)#A19'@>71<+G9D'@4''=??'G":
@r4288
CNCCAAAGACGATGTTATGCATATGCATTTCATNNGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTNTTTGGCGATATATTAAAGGTCTNAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAANATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATCAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGNTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCNCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTNCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGNATGGGTATATGACATCTGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGNTTTTCTTTGNCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCA
+
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
@r4289
CCATCAGATATCGTTCCGTCTGGCTNCGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGNTTCCTGATATGCGAGGCTGGANAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACANGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCNCAGTCTGAGCGGTTCAACAGGGGCCGCGGGTG
+
,@:=,2;3B3;.A@-#@:G>%:G1'G14EB9!H=0@E#???6&/+/&*):%"2:/4>$3<G"/2C@42-H'3)!9C<&9EA+<8D:+:!;/.&AC03H.;%7)+*<1A>=<$A"3+)560$DA>D<!&/**9D30!/*>-3,@$.61;99F71'B>!,1A&CA"*%12.8>C62<09!&8?1'DC?3"3$7>9*%'2H!6-+!"?;?B#:+#G+3,%</))D3H-H?F@G)'/=2:6*./:*E&E76?)AB-&(;$+,8+1*("/67%AG.'E!)=7?EA--H"5.E#"G2E:?EF+$39!$,.00B33"51//DD!4*<#12.)%*5E3<(1',&=F<D/;@B'E&6'41B
@r4290
NCCATGTCNTTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACGAAACTTGTTCCCGATGGAATGGAAAGCATATAATATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATANTATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTTGTGCGCTTTCTACTCGTGATTTCGNTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACNAACNGGGGATTTGCT
+
")!&)('!!+&((*!!'$($+%(%'))##%$+&('$*#%!'%$+*&*(&&#$&+&!'#(+'#'(%!%)"'+)*"!*%$!(!%+")*%%#&)%#&!$'#"&"+$"+)!#"#*"!*&'()%&($'&(*$%$#$&"$%'*)'###")%#(!*)'*"!%#*$%*))!'"!(""(($$&%)!$$)('')""*$!*!%"%)!)$(*%+'#+(+(***$"*+"("%%!*$##!)#&$)%!('+&#%*&*"")#)$!*'+$**+!"&(()'&'*$*)#$)+"*&&')%)!"+!"$%$"*%(#*$(%%$"&#'%)&&++'!"*((*##!""''$!"*&*"'!)'(+'!)&!")#!+'$*$#"#%'%$"'++$*+%'$#$*+#%$!$'$*!$!((&"))"!%!(#"&+)'&(*%)!$%'(+!$&)"+''#**)!#(*##'()+#&++"**$#+'+!$')("+*%*'!)!(%!#*+*"%+)&$((%%!)()+)*$$!&'$!"+'*"#')&*")*%()#!)($''*'"!+!')&"#*%#'$!$)%+&%!+($##)*%)'"!*(%))#)%*$($'&#'*
@r4291
CATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGNG
+
A:D#=?7*)5%:4H*/2@H=%F52(2),;@'<;B9'19;1C<-H;6#!E>G/0$?=C-B-(C8&&<C1@G
@r4292
ACAGCNNGGGANCAANNNCACGCGTGCTNGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCANACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGT
+
($"#*$#'%!#'&'$"&&'++%&&#)$+$'#%+'$%'+*")'"%*(')*!*("&'"'+*#$&#%)#)%%+(#&')&'$"%$!+(!#&!!&))%"&'#'!*+'&)&'!)$"$)!)+*$$!&'*$$&&*'(()%"#'$&$)"'#"#&
@r4293
CCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGNGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAA
+
'EG;67=.*HG)":1A8!6<>#!)6F7/G@0&'B;GA@$$C4.3HF$:#'+EE()+*;HH&7D!>.EB$69/.<$&*C;E"40"@9(%=H.G8C(CH)3D;+<1%91ADG4))&=9C0-E.02%$D'#:D6F%7GFE59+-C,?>5CEC"H=8<F0+<?&"*/2DH,'CG7<??$=$%>
@r4294
TATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGNGCGGAAGATGCANAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAANCTTACCCAACCCACCTGGTNACGCACTGTTAAGCCGNTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGNTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGNTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACTGTTTCGGTTTATANCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTCGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCNCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGNTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTAACAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCTTA
+
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
@r4295
CACAGCGCACAGCCTTTCGGATCGAACACGATCATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCA
+
E'E/=65CBC:)%7/9$*5%-,/7$>4*A:.67'&E<!;=>6+55DA+C=%5)*@G&;.E)',%&!'(!9AG!>9*=6A,!#82:H?-&-;("5@$"BF'029=)"-G5&2HH0?168G,2.G365)AFA#5'=G8G#F&*-/5-&"'B;?";>>+C?D$/04
@r4296
TCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACCGACAAAAAATATAGATNATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAANTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGNAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCA
+
#E:40+&H2G9&+GA>'/&/E-@/D(25=CB89)FCH&/8-)*+C!*$'+)0B9'77*7/AA1F33,4&/:2@5%D;&BC!-%.1HA+C9@8H.+(E+-H*=B*G6B0#4/0G"#76>93@A96)"('.$.B=4<G612"'B"/)<$-.()G?)3$*??6:68*B%(C*29=B*8!A6E2'2$459#.
@r4297
ACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAAGCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAG
+
H.'00B%@#2=7C;;;9%!:6:71&&F4<?.&@@,%(E%F+9E'F3'34$4*CB#60C8@53G,,9&60%G6B,"'1B>7/)0%2"+2/'.'7)*&"7E3GB&HCD@:;'-C#H:6DF&+98"A'%,;*+6D=;F*2EC<1F%H1B34AH&5D'&@<6/)7+3*:=G>.((D
@r4298
CGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGNGTGTTNAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTT
+
%'+"!!')"!%++%$)!($(#&!&*#!(*)"*!+))**''+$(*+!$"(&#%&#$"$$&*!$(%*(%))**$$$%*$!%%$&++%+($$%+#(+'*#*'&(+!&)$#*#$*"()%(''&%!+&"$"$#%)++&#&**%!
@r4299
ATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCC
+
&=5-$E+C97+#=,7"2A%%3*F<:'*D8"AG76-C/):FD.0%==9E0
@r4300
ACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTGATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTA
+
G/0)C1GC%3?/%!!=087'-??5'C81/$D;)()/&69=%?.E@("93=:374?<*CD;0B@?8$F1;*3<A:C95(/BF-.")FCG.9>,%(7F.5H6$">6&-$=3;@2E%2:5!1412/30C?9-*@46G-EE>GD!*G%F141FF).F<"E61$B2?@DC%F#=+$"8;6A&8<='DE):@$0&-/DE-@-6,*-.%$AHD18-0)H46CGF>#60$8+?-A(>C-#H)!C+70?3H')!,1,?H'<(/!6++E(D1GDDG<(C5H94CEC0<5'@DB@GG%83
@r4301
GTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGC
+
3$B#'9$/-G.8H009-"3.,6#'-2?5<4/3@=*B2EH0'7-4:C/G6G,<;:2393H%48)E170H#<(H=G82#2'6:G=CC51+AE&6"0)9;7$;51!G:F!DE.88$E.="%;2/716H'.&$&*<>4')H#HF"*2.1%&5/*!#)?>21.-F3
@r4302
CTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTNTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTANTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCCTTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGNTGCCTATTAATTTAGTTCCATAGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTTCACCAAGCGATTCATCCCTATATCGACAAGGACATTTTNTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCNGGAACTCCGGGNGCTATCAGTTTTTANGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACNAACACAGAGCTCTTCATGATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTNGGAGGCAGGCAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACNTATTATAGATTTGAATGACTTCCCCAATTATTGGAACAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAANATAGAAAATTACGATGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGANGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAANCAATTCCTAGGCAGGTCATTGGC
+
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
@r4303
CAGGCGGAGTCAGACAGCAACTGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCANAAGACGCAGATGCCGTCCNTGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTANGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGANGACGCCGNGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGA
+
62497A;@9-@@#88FB#,0><3!C:".B8+B%BBG(-,/>1-E==H6/39!589A#$EH=@G@=;?<*DEH!@1A%2$,#&:H<E<9>9F!.(AD%G$'"&.DD2H274&*,H?CAE!+E48@,&5%EB20>F@>34.8D8;58%*+09CC%,**?%.D#:EG2&(%2@/1$53=3$H=)F(D"=<0A46"#D(2E5-C.!,.8()3E%+0:33)A)2&A?C%E/;F/!<:*/@9C2(.*<*D%6:C$?0$-5%F!!HF!15.#A/A=#DCC0;"9&!A=&,6GH&$@H:09&EC")F(C3/>'G4=:*-0$,9:E4<*%9G*<32BB<)!13?.1
@r4304
ACCATCGGATCGCTGGCAGCCTGNTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGAGCCGGANACCGGCAGCACGGCGATGCCGTTCATGACCTTATANCTGCGGGCCTGTCGTGGTCCGTCATCATCACNGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGTATCCGTCAGGCTGCNGATCCCAAGCTGGCCTGNAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCNGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCANCCGCCCAGGNGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCATGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTAGTAGGTACTCAGTCCGGCCTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGGCATACGACCGGAGCCTATCCAGTCGCAGTTCNCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCA
+
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
@r4305
TAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGANTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGNCGGCACAAGAAAACCGGTACAGAACTGCACCAT
+
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
@r4306
NNGAGCAAANATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGNTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTNTTGGTGTAAGCTGCGGTTGCGTTCCTGAATCGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTC
+
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
@r4307
TNTATANCACTCNCGCNANNTCNCANTGNTAGANTTNNACCCNGGNCACCGGC
+
#"#!$!#"$""$###!#!"!##"$#""$#"$$"#""!"$#$!$$#""$#!##!
@r4308
GTTTCGGGATTGCANTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTNGTAAGCGCCGCCTCTTTTCATNTCACTACCACAACGAGCGAATTAACCCANCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCNATCATGCTGCTAACGTGTGACGGCATTCAAAATGTTGTCTGCGATTGNCTCTTCTTTGTNGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTNGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTAAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGA
+
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
@r4309
GAAGCCGTGGNCCGTGGTGAGTCGCTCATCATCGGCCTTTTTGGCGAATGAAATTTAGCTNCGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGNCCAAAGGAACGTGTCCGCGCNTTTGATTTCTTTCACGATCC
+
D@B'<D)5'G>*!CB%=8C-$7">;+AFFF>4+=22==(@*&+*(9/>9B#4?,A@5G07B/?2=*$*<<5&B.7->)'4B@71*!6&7F*&+&$;3CE%68')5";-HH!6((F)F(1?1;2-&16;7&#E*<%$B1?G@)AC1.?96'3E!1;0>7=DD+:1)!8&17)</%#9C.128F+%E7%90)FD$?&-C50;,*!'@.76(A*?+,>'B=":<C>G2A
@r4310
NTGCATACATTCAATCAATTGTTNTCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTAGGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTTAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACGAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACNTGTNAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCANATTGGGGGATTGCTATCCCTCAAAACAGG
+
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
@r4311
GTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCATAAGGATGGTCATCGGTCACAGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAG
+
$+#&)%+("!#')#*$%%*"'"%*"+%((#'$'()("$+'(+%%'+*+&&*!%%&'*)'(!*!'#$$)&###"$!))*)!#&'$+%%($!*)#!++)!*)''("*)!"#%"&$+*'%##!(*()'!#'%$(#%)*(+%%'$$)"($)*$(()!&)%)&#$*$%")((*(#&&'+#!*(&%+'!&"*$(*!$++$)*+*#'%(%!%$$#!$'*
@r4312
TCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCG
+
1=E30..!A$1".8+9A1#*$(=>8H5;G"'(?)C$)-*/-,.%#1"!C1#/
@r4313
ACCGGATCACCAAATGCGTACAGGCGGCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGNCCTTTTACACATGACNTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAANACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTNGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCGTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCNTATATAACGAGCGTGTTTATCGGTTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGGTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACNGATAACGGACGTCAGAAA
+
7%.,1@8**<(278=;50<1$2#C-%<B=*E.#=1/3G,@/D,%.--2BAA=?@GF@15==2&%/#3(,4/,1FE<*)6'+-H?E60<4-$*!/$4H*6'@=&E,(05;*=E(:G".63((F!*%<#.3&#<DH%3(FE!<(ABC%C5>+-B3%%D?&%+3;BA0A38($B@D+9;H+F!%E5"!CA<E*0-H+4DF1D8:*CD<,:05),/5)3<51+9+!5.DD;51-1.5+>8G>CC&3,.+.@1++>!.9#60)C82-<&2,F&"8'BF7#9=602!9=H,/F,#/70.0D975A!*F>4@$896FB&AG%)2.H3@B4""H1+/E9.25"?C6?'4G%4H!2,#62HGD?B9.,4#$(86AB"G9/$=$?E#;G=-84;C/2":"FH##17:*78C*@@3"<$D1?,-HE209D/-;!6"H-:.F#64#6821E.?H@",G>H;'1&*E38HG#,>09-+ADF7=,D;"G;D=A8(,G*$/>BF=0B-CHC#GE>+C"4/)(975=,A5B*G!'7:/!7B?),4+B.)$-)H5-1*G(90A<A16//F%;!H5*)=?D4A)64)?$CE'+)!B,+3F#."#D4G9&461,*>3A*D1)65&A/HGCF",C;8<1&C"0B,1<=2:"201">B&5):$!+4A*=4@6B$G?><"H=E;(73=;';#;!85&49@:99DC@
@r4314
GAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGANGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGANCAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGNTCAGCGTGGAGGTTCAGTCCGTCACC
+
<?$2%4/&5!7)G.;)9:*).=HA6$,H829F1"@&+HG7@?+FA>&9)C+H#03B;"8$H&35?!04-<&83&$!+'@;D&(/)4)<A6$#1H,'&1"F<<32'*#/%@F.1%8H%)A0=BH;67A7%0G($2.7'+F;?<+63A*<20CE+$-/*1G-74$<)9#3<9-C;>56D)1:51D?H%$<2#?2B"&@=D/.@&,G%'+<6::,BE!('A!H-)@,::';/AH=C(=,;*0=C43;(@*A#,#G3//
@r4315
CTNNGGCNTTCATCNGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATTTGCCTCGCTGGTCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTNCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAAAGGGCATTGCCTGTTCCT
+
%&#!%))!#$$%&%+&"+&$*"$)"%)'*#+&'#")($(""%+*(+(*+"*#$)#!$)(#"*+($%"'%%(&$$%!$*%%$+*!!!"+$%!$"*#$+)!!&(+%#**(")'$%$$#*")&++"%!"**&"*'!'$&"*'%$)"*('$$#$%)#%%'"##+*"*()!#"(&*'("&$)""%+"&+&%)"(($'$%!)"$''++&"'($#+$!)!)#*''"'*('%)#$#(&"+(&(+*%*)&"%
@r4316
CATTACAGGAAACATTTCTTCAGGCTTAACCATCCATTCCGATTGCAGCTTGCATCCATTGCATCGCTCGAATTATCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGANCTCTTCAAATTCTTCTTCC
+
2C53(3E>D9)G,,DB-'?"D:6$-9HC(8B4;5:B;9#%H!-")8=<$89!0=77:&*;*4"8&&+($5D$/A,$5!9<?07H>$,&*CC4$&C;%<C$CAF3>=F009,#9@7#GGHHD/D/4G5H&0&8-A&(!.=&D22H;0-%CC-::'G72GHD3!0G5*6&!*F#HF3-8CF
@r4317
CATCTTCTCGGGCATAAGTCGGACACCATGNCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGNTTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATA
+
38!&32D$HD=4$2.7H1;$7#3C")'G=0H(#A+G2A1F!8<G*,H/D*$5!-C$'<+;@H&%<,9'--*0A=C%9;(1599%G&<?@#F+641')!B,#A;3%,7H%0"*!H5-3#&%E=;AG2(H?$AE-0/<'1&2*)2*1AEC>7#-;4#G69;$=,HC'@-H96+)E3):#;7=*(B1=D?$156"CC&59'5G$!.15
@r4318
CTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGNTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCT
+
!C,;#=@D.#$2@!%7B8!.;*$279)8(BG+?!&,B$+EEF.>/G=(>5%%.":0+#.@#G?/+$.?'6:!60F6.&%2!30B8215)A+=9FG3@%(:(EH/)CE./5DB&35B=#C(A=,
@r4319
TGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTT
+
%G&78"D=038<7!B"A1+*+,G8*>4CD!*$>((>$860',*42$7/11&+C%=C2D&'0E(4"C@6G&,''DF-FF?B<:B!-'.@A.@>(*'A;G6H6E:8,7=54>*91+C-'
@r4320
GCGCCTCGTTCATTCACGTTTTTNAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTAGAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAG
+
)<$E->B:'DFG>!7;5?)<0B@76?-&AA+.!7>17/CA17.!$1?4)+'F#,3E0".C/:.!+672*.E:A#HFDG6&(&4.(H*+)%A7G4"*9'."$=9#6@&AG,FD,:?)<3)&!-GB8F.4";)-6/?1=C25>2H*''<E%%.!!5/:@FF)4
@r4321
ATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTNGGAATATCCTGC
+
B.75;F7%?F9HA/#78?-,,)D=7H@2#D"?-4F-@,C0!(;:5@6)B6G&E,B95.?=&:"!014*'"?%#*C3+/=)1H@F.=)>8'5<&.7&-H/,#,$/;G5+!0#&3$';
@r4322
TTTNAGTTCAAGGCGGTTGCCGTCACTGCATAAACCATCGGGAGANCAGGCGGTACGCATACTTT
+
:-"?#1*1%<?,)+*--A&,!7<G=.%;4'#G$$)=6G"+;.%+H5%97)%4<*>D;5?&<B.(B
@r4323
CTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTT
+
9*(1?:F7.82<%(()""5&902,)A/"GB;3;>!A@AD7-B;6*);/H>,HH@5H:2D.;,2/)-F>DB&8-$#0.4F=2F.1'0C,4F$#40.#G/>&0.6&D/3897>DH&?%&B2$;&D<211.;+B(/!G9&"C0BC=))$H6+:,)3$?3D=8CCH':#3D76"3BH(E0>)$,(@H$4A:5)D4/7B>;!FH@83B%;9+"2EF#)
@r4324
GATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCAC
+
8"H$1@3-!$'C5:(9%::,G<3%30>,%?A+:0G-?*)?F!,*2-1>+1&2>.D-+:4.+-$6?).E'%82A+/E,$7#-(7&@EC%")%
@r4325
GTGCNGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATNCGCTTAATTCAGCACAACGGAAAG
+
-FD&)(')+!(<);/+),/BA(?>)-=8#76>$*D,H%(#1>(!53(9CB(F(=B44F+.>2AGA&F)./9A$DG>(%G6F:8;+#BC
@r4326
NCTTTCGTCTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTNAACGGGCTGTACGCTGTCCNGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGANGANGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGCAAAGTCCAGCTCCTGCTGNCGGATGACGCAGGCNTTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAACCGCATAAAATGCGGGGATTCACTGGCTACACGCTCAATCTGANAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCNTCATC
+
:2%!A=.:A,4#:'"G2$?==%#%4:>HH/=;>F<-4//;.!0.;!@$<5:'F'%F+A8$C)"<0C(;?",,(=G<)0//;0CDA8#%57:,FE>5,E<+=0B5F9)$*+/<37.+B@=,C".==@%?9EC"<D46*-F<?>,@3/&B4<-*+,*A;-A<F=1F,#,:83#A:F9@>:+/2;F#5D)%$7B%((.D&9G":(A3D0B+E:1:F*&(%$?(+F>-4556@A"AH+&F=&%0E%256>FF67B9(0?AF;ED43$E:23&%.<-#"AAA7*18>)%."!!)%5-G2*&@#3DE<)6(67+;*>6'@-A%"6",<7>'@:,0(!E9.:<"<3-,,B6-H'9+%8#;:8&%&&)"F8!@8E,<->$#C484E,6#&9#!#D)/C%#7#6<!&7E.:9.!&EF)#73439"0*70F:17H#AG,!?'G!?%H3"&A%G=!.(506+C?7.$'57F2%3-65;B;+H<B;*E1!>9-(+%1?F.G?0'<3
@r4327
CCTCTTCATGCAGGCTCGCCAGCAGCGCACTGAGAACCAGCTGCCAGCGGGAAA
+
A+A?G,#92A9G"00ABB8>&&,<H<D&*F&&/.7$7*(0$:FA'HD#93H&'1
@r4328
AGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCATGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTNTAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTG
+
05A:7=.=-58$<3?H>,=0,+DD0,%007.-F)(;;$;5&B3?<.(?$8;.E259>+#.C94/0'BA55!CF:##=!:&&8<:)/33@/8:*:#+1&@A'#4BF@,>!$<>DA+B)!-."H24H-G#=5&!+&$0E9B'5C101)7179"@3,(.F+GG724:4(0=8%"B<'=AC1B(5/"27D*.@CFG#1GA&A;C2-(6<6+D3C#<$E=#67+*&@3?4&E!D45+-5(/A,'?E4&(C:%=G9070<@/1!6$!9#=,:8&+<%=B'79-,!6/$F9C1+&F=D!6$>&-<@C500>074.
@r4329
CGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGANCAGTCANGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGNTCACTGTNCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGNATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTAAATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTNTAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGNTGGCCCCGTGGTATGGCAAAAAGCACCGGNATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGNCTCTCCGNCGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGT
+
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
@r4330
CGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTGGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTACGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTANATCGTGCACAGGCTCTGGCGAAGATCGCAG
+
F3?#;3&7,9(4GE(9=,F'3$FCD<73-='(D/%E'>)F;(23).4-!:.9:,:"E1(-F:</(B<<G$%?,-F8+A<8;:';EE&*.H/@G5<3,G=B@&6*!BG:/4=(D7C;%7!CC7E86#G15<F/F34/3EA**4;;(E>3495445(<D!8G4E',A5E.0.::-9*C25-=2(*3/F>G)5CE%)?7##-",G+!>::C$3)-(;3FEA1@G&-9B<@5B>++#D?B<,9/3482E0#?)D79.2*@2(%(D48E,E)32&7A'?!7?#'B6"12&D#6C<#@<+;$"2HDF$1<:1'+.##,*86-%0-?G/(&/D'!)>0
@r4331
TAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGANGTCAGAANACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCANATCAACAGGCGCCNGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCCTACCG
+
+%'+*"))!++$&#+#&*'+!%%!$'!"#+(!$&)#$!'&'*)$&#))#%!#!%"+'&!()$'#&!*!"$)#(%(!%(('#')&)*%"%&''*%+*&++*+('&'!+$!*("")$#)+)!")!#&&!"%!!#)#$"'+('$&&#($+$)*)$++*('$)*%'&)!($+""%%#%'$$%")'("&(()"*+$"+"&$!+$*"$!$"%")(&
@r4332
CNCCCTATTCTCTCGCTGAANCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTCAATACCACAAACAGATTGAAAGCAACCTGCAACGTGTTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTNATCTAGTTANTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGNTGGCAACTAATACAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCAATNCCATCGGGAAAAAGTNTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGNTGCGCACAAAACCATAGATTGCTCTTCTGTAAGATTTTGAATTACTGATCGCACTTTATCGTTTTGCNTCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAANAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGNATTAGCNACCCATCGTCTTTCTGATTTAATAATAGATNATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCNAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATATCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGC
+
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
@r4333
TTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTATCAGGTCGATTTCCC
+
C,#+>('0+):#2$'*%D*@9$41E;62"$7(;'"612/<:B@,-A>?A?491,@)0;-62=H&2
@r4334
TAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGATTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTNTGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCNCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATACCCCAGAAGATGTTG
+
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
@r4335
TATCTGCCCGTTCGGGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATC
+
%.<>2E6,8?F.<F!;*"4<2C$E!'@+0!!1B8EH*#)%E#.HD:5%#*5AF*H*:G80.?A+8076B*!9<C@-5$<*=>,HDG?:,$B0)(3:1@1:20A8-A'4)5@!#&B'C6&F-/F-2%$61-21D2.()4C&B*D'1!.',*)=#3?/>3=.
@r4336
GACAGCAAAAAGCGACGCANTGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTNGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGNACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGNATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTNAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGT
+
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
@r4337
AACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACNGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCNTCGTGAAGATAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCNAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACNATCCCCACCATTGCCTGCTTAAGNAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCNGTTCTGCTCACTGCCGGTCAGCATCGCNGCCATATTCTGTGCAATACGATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGNCGCTCTCTTCCTANTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGANGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGNGGCCCGTTTTGCCCGTTGCTGCTGTCCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCANGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGNGTTTGTACTCCAGCGTCTCATCTTTATGCGCNAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTGCAGTACCGCGAACTGACTGTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGNCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTCCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTG
+
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
@r4338
TTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGNTGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGANTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAATTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTAT
+
#7@/F;(H*!"B-:=8,,G$557,:BA-3?64(H'$'?2;&73-"!$+"*&0#&H%G0HB2;+<8("(0#:+7C504+@EH+!+*=;*3:)94C-3D3'ECF-/'994/B-9&5>C=>A:"HD'B3B53;8*;?/&'#2/>=G=+0'?AFB;=6!FE8*,C2="C0'G-F3($C<9.>*1%G)!3%3AF3B/4D54&0F8'4!9*9&-EG2?-2F/FB35+/;'>FF:/FA1#G14F6B+@HEC77C2E#F(,9@!/',/
@r4339
GGCGGGCGGTTTAAGACGGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGAC
+
=>7FA:,12.#4!F.9>!%":1CFF,)7-(A=&)G/3D-*$(<='$$6+=H().F2?+)2#!21"3->-+"7<68;D#57-3"3D9F!#(5$(,DDA6!430C4D0/#F::>732-%:C*D48(>!4/HG:C)9D,62424-2A'C2;')+$>?%>!D
@r4340
CACTNANCNTGACNNNCCCNTNGNNNAGNCCNANATCNCGCGGCTNNNTCAGAGCNATACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGTTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTNTTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGNAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCNTGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTAACTCCGCCTGTTCTGCCTGCCGTTTCATCAG
+
$'"%$&!)""*$'!)!#)"#&!)$"$*)"%"#$"!(*$()$$&!$!#&!"%&"%)!("+$%'*)%'&'+'$$$+!+!"+"%"&')!")%%#$'+$#%)'"&)+##+$$)$+!&))&#"#&$')*&))$%$"#)&!+!*&'**")##%"!(")$$&("*('(')$+**"&+&'%(*)+%%)"$%+#!!''&$&"#&)"+"&'!#"&+"+*%)#%&)'+""#$'!)"&"'%'#"%($!%""%*))&+'&++)'$'("'$+#$(!)!"#+$(+*#$(**"##!"!*'*"&)%(%)#$&+#''*#(*&%""%!(*$)!%*#'(+!%&++%'#+$!()()!*%#$")%((*+#*#&+###$""'"*#&+')*('$)&#$&)!!&!*&&#'(%&!&$$%
@r4341
TGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACT
+
;,.<!E-$8#8:GE",:3"6H<<0#;??*<>965*E'1D!#D3&==91?%%?E36*(*.H*#G62->/$.).+;G48
@r4342
CGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCA
+
G62"DB/30$%-%&C%5!2?<4#2DD.302AB<07H5#B==<<*.<$;@E0$&04!>6H);.(,7
@r4343
TCNGNTGNCCACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATCAACATTGCTGATACCGTTTAGCTGAAACGACATTCATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTNTCAATGTTGTGCAGACCCGGTGTCTTGTCTCCATGCAGACATCACNAAGGTGTTTATGTAGTTGAAGGTATAGATATAGAGTCGGCATACACATA
+
)%%"%'('$+((!)$%'#')&&$&"(#'%!("+*)$+"!'+''('+$('"'%&$&+)%++&"(&)()'+!(&!+$'##%'#'"*$#$&"'$'*&"#+"*&%#))#((*')($&!)+#*''($&+#&#((*%)!')((!($$#&+*)"+#''*#*$+&#""(*)+)%)%%")"+')#)**&'&)%)+'+'"*!+#)&$(*%$(+*++'%*()'!&"&*)'))%"%+%"!*%(#"('&#"!")'&%(()"+%*+
@r4344
CTCTGGNTTTCGTCATCCGGTGAAGNGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGNGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACAACACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAN
+
63<H%7':+<<-,##FA7;C?$,E<*:3C')%-D!GD!%8#?;:9/!F@0.?%.#<(+5:A+H-0"1DD99/93C77?,DB56<%3*C?-5&+'(@E'1-@1B?(D9&,4+/5;5A,92&7!F1<D,*(9;!%A/*H'&&EF5/"?69B1'3#?9(2A>92'D!571#E82/*35><$'-3D8EEC.*D$06:1>9+B@!9:C(?@=G(*7$@'9;9))E&"
@r4345
TACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAGATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCANGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACNGAATTAGTTGC
+
)/?A;-"-%)<E=<0'CB1#F&B:4:A:@D!/H<30!%G2$%?*2A9H1584;G34%82A#-,!&.)'!:$:#?>3-*<*(=E=.4"A0/*%/:(<*AF:#*D>/>FG33&=&+74=@.E8)2,H5-45/*)D(':8?;$(.4,+2.#!/16(7=G&=/03"2C%E.33,;=:*B?+6A-<=>+"G7"$>2+/E'7B=0')(:,?&8E69:0$/18<62=>+@;)4+5+4>3!E#).8F0@BFDA0/<8G=)0C5*<'')%F7(#=?G".-8A%*>C07;4&:+';:$.!C0.;-E61A)<#;>B+%31D.6>$C*/)!;F5':2B:(*$
@r4346
CCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGACAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCNCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGATGTTTTTTTCGCATCACTTTCCATACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCC
+
+#")+%)$+%&(""))+'")&($#+")"!&!*#'!#)!%&(+#)*#(%#!"((+)*!*&&*'"$#"()*#*'$'('%$""%(*+*#)*"%%+!*%"(%#*&)'!($&)"*)&&+'!$**'!"&'')&)$#'*+#(#*#!!"**&!&%()")#($#)#"&+&%)&'*+*%*%)%)"*('!'%#$(&)!!!%()$#%")"!+$'!&+()$"!!%))&)()%"!)'
@r4347
GCGGCGGGTCTGGTCNTCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACANGTTA
+
.)-$+?7H82.G#3,#;?'GEDA2A3ED22%8A!6C&=%>FB%0$H##?=9$.HA5A)0B!4.2=?*#4C1"HB/B3&2>3#6+E"?#5?E07@,B<BG-3BD!>H1$?96;#4"*/E3D&
@r4348
AGCANGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGNTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGNTNCGTGAACGTGACGGACGTAACCACCGCGACAAGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTNTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAA
+
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
@r4349
GGNNAAANGTCAGTACAGTGTCATCCTGCAGGTTGACGGTCTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCA
+
&*!%&&!#!+(&)+#(*%+%*$""!#("%&%"!#%%!**""*(*(&()!'$#%%'*"'#%$''+")($(&*!(++!&($*'(")&#'&%$!+#"#''"%%&"$)$!!+(##)((&%"!#"'"#$#$!'"&!)+$&"*!#*$(%(%'%)%%($*(*!+'"#%"&$'"*(!"%$&&$$***$#+*)$()&"%!%+"")%!!(++)*"''"&&"%(&!##!"#""&%"%*'&!&"%$%'#%%+$#!"+
@r4350
NGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGAGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGNTGATAAGCCTGGTTGNCGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACANACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTNACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGNTTCT
+
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
@r4351
ACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTTATTCTTCATCACTTTTAATTGATGTATATGCTCNCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTNAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTT
+
A/0*1CD,$<7)"0!&(GD!F$&==F1,BH2:AEB8;$(+%#8C.91.>15=B"8)A%(6DC"9":#6>@7'0&-"+<<<C?%E(9)8H3.,AF+@!)!=H<$51$HA94%,7"9#F:B6>6=7.-G>>DB$*#0-3-G9D2>)FH4="%(!;:!AD#><C:(+G(+5<00?4+*<%51/3:4?,)4&H;C5-?FF?F?5,+9*5/<(&1":(5@5("-C>$@E9"7E3155(00-GC3<5&1-5<C@@12#9&A";%+*.7=67%9'5#%A
@r4352
TTTCGACGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCG
+
<#-8DC5081!-(;'=#-66DB>1';/+?=<)G%/%%@;*-CB92+AAG>5=1D3"77=EF&024
@r4353
GNANGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAANAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTTCACGCCGACGGAAACGGATGGNGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATNACCAGCCGACGTNCGATATCACGAAGGATAAATGCAGCAAATGCCNGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCNATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCNTGCGGCTTCGNGGTAAGCACGCCGGAGGGGTAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTG
+
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
@r4354
ANGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCGCCACCATTGCCTNCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGNATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCNGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACNTCAGGCCTGCCNTCCAGTTCCCGCGAAGCTGGTATTCAGCCGCCCAGGTCTTTTTCTGCTCNGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCACGTTCTGCNTGCCGGTCAGTCAGCCCCCGGCNTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGGATTTATCCGCCTGCTGCNCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCNAAGTGCAGCCAGCTNGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTNTCCTGTNCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTNCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGC
+
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
@r4355
TATGGCGATAATCCGCTGGCGCTGAAAAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGG
+
(+!+++'%(#!'*$+(&(((%"$%!+'&)'+)&*)'+')%$)'*)"%&$#*(!#!%*#+*!")'%)'(!'(*('%'#'+$#*''((')$&!*$)(")$*(%#(*#)+!%&*
@r4356
NGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCCATNCGGATATGCATCCGCTGGATTTNANTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGATGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCAATTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATCTCCGTCGGGCAGTATAAAGCCGCCNTGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGNGGCAGGTGAAGGACTGCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCA
+
#&(&++'*)+(&#*(!'!+'&''*%$!#))&""**')!'("'%)&++$+%#%#!+"!#$&"#"(!%&!&$)$*+'(+%(*)!+'%!!$+&#&'*$$+)!+&+!&"!!#)%+$"(#()"*&+'&%)#'&'"('*'%!$%$*&#++#(+*&&'+'#&!"%##&()!!("(!+$"'!(&"#)!&$%"+%(+!!)"''$#"&+&+'%&!!&&$($"&''$*+")$*+#+%)')$%&(+(%)$"%)+'$!!(&+(+&(+&'&$!%*#("%'(+%#"*"$)()'*!$#(!)'*(%"+!#"*$''*&"%+%+(!(!+!%&&")'#!%($&%("'#!!''&(%#"*'*())$$!))%("!'&"*$%#&&'*+!#"*)("'+)!))$")+#"$&')#&$#%*##$)&")("'+'"$$'%#*'('#)$"+!#$**)(""**%$!)*!!+($'*%&(+!!!%(&!)+%!('(+&!&)'(''!$$*$!++''!+*'&+"$"$&"$#*!*+!)#%#$#'+&(*+"!&"&*&'"+&#%!('&)(+)*($"()!!&*!++*(&'*&#!#*)*!'"#*)))+"+')!+'"$&)"+#+)($)&*%***%*((&%%%)#*&#&$*
@r4357
AGGACAGACAAAAAATATAGANCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGANGTGGTACACCAAGCGATTCATCCCTATATTGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTANCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGNAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAGCCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTANGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTNACTTGCTANCCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGC
+
G-;>D9BF%>=0+B#!H8F(B2'+.!8E5.0/94D,D(?6&C3:'9%?(?;?,.*8(:'H,@,.70&>?B52(15<?8!('>)#'3"4B&$5-B.F687D525"-=-29@D@3/,/5,>6;G!$-2(DD=:7/&,/H1,".E23H@%"/.1%?7:"88)!6.):<'B23<-/&H%FB?!0/3$$!;-B/(AD.@'@*)!6)2A/:(1E6%@7/"35"<B;6#0.@4HB2?#'+*+GE/?D$E+,E#=GD%7:DD?&G",?F$8+2'&F@73C*B$054#"+H>4C7%6E!($%"+><)7)9-"G@(8'!,8>83H;G37%,//(F6*#(B%&DDC3H)5::C84E2*C2H+-/9)@@@'B7'2,8/%"!H0<$!'3"*8)?%$./=?775GFGF()5>F6750E0/18!/<=/(=E&52@A3*1-209H7$719A2D1"3?-*-%:4"%%<%)'+?!%46AE<D,D.;AG,)C3=-()9D=873C#G,*%>#4C.=22;5G$-.7"/31D'ADAGE#>$=>5$E<!;6B=GH);(-"%0+/(*$,8"DH47CA4;6!DF"C)B)G-E.F;4D<9'G/@((<$$2H(8+#)(55%E4,D08AC68%#@>)B!/#E@'(70>?G4,5BH&/6*E)#29!6=;3.(G'%%D$BD6A58=5;F/.$:G6,1/,E<$;G&&22G")G6%;.H,.$%74'$764/-$<"8C)9G-=DF.?+A5!H"612!H:C=8!5)<,!!;G"0A*3<1!B)?:-.;CFC>:CA4G.E)D1A37C;,AHBC(:::7HAC('6H#@4,F=28H%#(:;207&21&#$&;4=96H0G:E854'A,86C):(9):#(38(C%<"3,"'?+.#C,D:&0D87<!(-/0.<7/)(F073!7/2,9*?#A((+E!#(*&&251!D7#,E8808#H/.:5G$,*:<*5)>*
@r4358
CANAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAANAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGCCAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCNCCAGCTGTCTGCACAGGANAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAANAGCCGGGGGCTGACTGACCGGCAGGCNGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCAGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTNGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAANTTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGNGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTNTACCGGCTGATGCGCGGCTATGCCACC
+
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
@r4359
AAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAANAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTNCATTCATGGCTTGATCGATACGAAAAAATCCTG
+
B/C@F>D"HE?48:H)/<5F7)4$,75&*!8F3$H4=82%$'&C.C39)5C%&C..1G03$=GD7">?3%HC.D,)>!9A"F,+81?$/A@=3AB48#/"@46<!3FH8A1G8B383)&A<@<:824-G10FEF)'E0E8(:6/:=/9DE/!#;(:<178F2=@7.50$,3#A%;2H-<,00,H!C;E,(>77'A1:1708H>E7"6!/2@>G?9E-("7.BC6>3/%%?/D<)93'C1"$4H+52D5;="B")157(;<9B$&#5B/@4/0>02B$(F##>:+92)1;D9:':(&:95)&=H3B".
@r4360
AGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCANGTCCGGTCAGCNCATTTTCCCGGCTGAGAG
+
?8#C$*E/D!-.4409+#3(8=AHD3E68/5A)2"@005*A5<+%&=)@$8DF1(),3%+H(1>29':A1"H!(6GCD8<*%%(9G)5
@r4361
AGGCATAGTGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCNTACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAG
+
'$)%$#*&$&(+&)"$$#$%"&$%*#)+&"'"'%)'$++"$'+')#%&')$'%(('(*!++!*)##$"&+$+!*)"'%%((#*%%!%%#+"*)'%#!$)%*##(!$%*%(!&(%$")#((#%+&&%%*&)(')!!('#(&+)("&)##&"*$!$#!)&!$"*(+(!+&+)!**#&('!*#"(*"&*$'!!!+##%$$"!#"
@r4362
TGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGNGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGAATGGTAATAAAGCGATGAAACATACTGAACTCCGNGCAGNCTTACTGGATGCACTGGAGAAGCATGACAC
+
A3/HB==(#E!D4./0>';HA/D#('5F4'76'E->.HBE6B*&:A'D9-&@/BE8<:;634(%89-@8%,='3*E+0EE9"B5';/!+)3):(6#DAC%#(F6">)B#"0:6:0&4HG1-##;",F2>82H,G=55ECFH**A+#E35H<E,2E;B2-(A)C+-6F.G03C!.<.,HF#A5:H(,3:
@r4363
GACTNNGNTGCCANGGCTTTCCACGGCGAAANATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATNCCGTGGCCATCAGANATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCNACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTTGATTACGGCACCAAATCGACGAATAACATGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGNTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGG
+
'**!"%)$*'%!&"%+"+"*&(*$&*+*$*!$&+#")#!$%&'$()!&!#"!((#++)$'%$$'"('%#'**"+#$(*#"$!(%)$'''#$%)(!(#'!&"%#+$#))#)'%)&(*$()'%&'%&"))$&&**+*")+!&$!$$'&&)('((#'+)"+(+&*"+)!'+$*()#'!#!*'!+#"#+#!#($*+'(%+#%$(#!*&%#'%'#%"%"!&'&"++)%&"*("$%)"'("(!('&$$&*&+#*&%##&"%$*+!%"&(!&+**!*&##)$%"($()%!'&%)"*$&**)+"#"&#!%*++'*!$"(#***'(%'#%')%$'+!!'++&$$')#"&&%+!*+!))#!$++&*$'!*$#)(%*&%!)&+!)%+"(***)*(#%*"*(#!$')&("#$#)!$*')+%%#&$))()!"$$*$!$()(''$*%$"+$*$&#%'*$+*$+()$$(!$"!&+*+!($#''*+$)#&*'''$')'(%#()%*)'&*$*&!$'"'***'#)+*&+(+*(#+#!"""#(&+)#))'&!"%+#'("#''%!"#'$!"#*%'('#&"*!""!+#&')++"&*+**&+)#!("+'*#$()%+!'())()%$)*+!(%$%$$#'+*#*&#(&'#%!#$()((#%""(#+*"&"$!%%%*%
@r4364
CNTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATGCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGNTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCC
+
B=-G>.$7),B&6D%"1<DB8%18/))H4#%-&180H&!-'@36-/C#D!/.F5G.DC/:D'+0)$F!6*,D%C00+A(;6@;#%B@?2H$)=B2@98.-:"/"5E)08?<!!>5'0&6/E<E;F(59G;F4$44-$(6'7>E&(8&,&BCGG(3E@89'+!'CG+5&*C&72B9/=+B1"89.3D3H?C.$BA8$4AF<$5"*$>3<*0'93,)6->971D-9%"D")A:);%5C:@18$-<%D32*&2)5=7/;!>073-?!9*(6$/:E,D8%+F$?$+;?(04$%D@##3.''D%E>0!+',9E3G&&E60,70;=5$6C2@$6//A.6#%)4HFED6?A!;F**6883!'.EECCCH0G1DD*B:+AA&F75E1*,9HH9:9@*(2HE?7;1@?3>G%9#>CC5@#!'8#<).*099;%8B@F@43
@r4365
TTTTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTA
+
1D79<;D"9'":B+/%D?F5733@-<C@$*6&!5>!(+$AG4E$%9>$A#2);
@r4366
ACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCA
+
(9$06@>D=*A'CF$8+'=62*8"56-'?4$A:*E:67F4.1'<H7C+>E#9"3A+;4$%H37'H0F/=-2D+"=A:C8&9AA2!$DC#256,F*B'<3,+G-<";"49@)B<$..?,@74"6,@=4G8,/0$!/5+E;%@0='&'F94G1EEE'22$"<C!>:)';C1.B#<G)."%?F6:<(C0D</$*><2",2C);%45#$/G!'/BF*EA
@r4367
NGGCGGTGATGGCNTACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCCANACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACNGACTGAACCTCCACGCTGACCGGATTGCCACNTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCTGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCANCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAG
+
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
@r4368
TGNATNCCTGCCCGTCGCTTTTCCTCCATTAGCCANAGCAAATATGCTGACGTCCTGC
+
"&!%(#*+$#*#%$*$$!*"&)(*%%%+(!'*!)*#))()!%*#(&!*!*"+&&!)*(
@r4369
ATCGTCCTGTTCGGAGGGAAGAACGCGGGATTTTCATTCTTCATCACTTTTAATTGATGTATATACTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCANGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGNTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACACGAGGTTGCCCCGTATTCAGTGTCGCTGATTTNTATTGTCTGAAGTTGTTTGTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCANGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAAATCCGCANGCCAGNATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGNATGTCATGCAGCGTGTGGCTGGGAAAAACCGNTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAANGAGCTNGGCTATGCGCTGCAGNATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTNTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCANGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTNATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGNTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCCATGAAATGTGAGGACGCTAT
+
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
@r4370
GCGTTTACGGCTTGTTGGGCTAGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCG
+
A?*)&8<#7-@;+3A>1;35G$<-:C0':E2$,B!,;4C2*>#?)@6D/43(7C(>#()?D!B&.%2#,75!DD!3$B038?A'<@FG<:<(4:E;><5%81D,2.D)7D(0+$+5)'?:$.BGC8)6%2+!8=5?5@B/;B?5E05G:2.&H=&>
@r4371
CCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGT
+
2.0+F%=G-@<6#-0/?%!1(0#7:3::'1/0"HA&EB)$H1:#@/1#"G2!9->/
@r4372
TNCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCNAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTNCAGGTATACAGATTAATCCGGCAGCGTCC
+
(**#'&)+#'!+*#&$+&)(()*)(#&&)!##)'('&+$+)("$*++'$%*#)!&!!'$%(#)!#%#+&$!+)%'++!*$!('+*%+%'#$#!$"'!'(($)*$%"$)")'#*(%#*$##&+##!'&'+&*"$*+&'(+(!
@r4373
ACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTAGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGTTCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCTGGGCTGATTAGGAANACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTNAGTTTCAGTATTAATATACATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGATGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTA
+
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
@r4374
NCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGCATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTANGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCNTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCG
+
%4'%3/B-G'-;B2B.<<AD,B2B"ED)2,!!'/1+(:.8,=3@7F6*B4'"8A09FD>6/9#:F+H=F6/?.D,55#$03;(+A5B3$5H=$9AA69>'5-G&H-??(9#C@!/:/:=8/&-/:@0B&6=<"-:>,E1/7?,@-C&CAE:!0648'-A-.0DE4'FBH12*.-:A@%@/*%HF82/;H=$<5/2EE-HE&&6$D:'4'4H00+.H@.+)>0<0==9&D=$6880D76+3<!,84>(69-D5B=34C,B&3:3B?+:5<A26"4F3<+"C582,*8'!.0=.6DHGE+:/F@;8<)$&%!:/=A&:37$C=(';6F$F@);&0634+@%,=4@C9%,1DB51)/.(:849!BG6"'B7E)&-82*A'G1;41,:&.A4-8.H9F,%C97-!?%4)E%.@?&?7(#BB94*,:(;-##%0::;?7:6#@1:%/&0H/C$!AB4"0!:H2+1D)F.H?;'%C"G.F<'=<'(.D@D/G5)
@r4375
CTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGANGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCNGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCG
+
(BG--42'"*"!:>#-BB9)<ED%1H:?+E$&6$'=F#74HB</3(D4C;?;F%D8#?BH%3(<D5G6$B56E+$0,'/:82G246.1#::E.,:/+&7CB+/$)/H8)"&C*!;+8="$&..!."2:?+/H+:7717E"D#?#70=F40-/(+')GH;?H?9D=0G>B%<D(DAA)290$2()@57G8(.C#!;B=E+,4+*$%*D$B)6FGB1?'&'<<2-)5C,:2;#'5/%@D8.#:@14>G:7?70(@#)>B06=DC9;GHG?+A<;2B&A>F!88*9/";*?F=6E43)?D+H9!*A0'ED@H-$<%C+#!($&+-$%.AFBFA.)<+E@&$)D:>*D@+-!*9C%?=#>H46
@r4376
CGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGNCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGNCTCACTCAGCCAGGGCAGACCACCGGGGTGG
+
GD:%,A9HH69@14@/B6#3599#/)G4"0+7@/$>0%@D?6G);.)'/7,A,99"",#F316D,(:EE!4"==79.+A'@/'?4GE;E#5?HB6B-7(%@88-/0*F18)1+3'1?B(@*5'1+;!969C?:00"33)G!%FB>D6?(66
@r4377
NNTTCACTTTCAANNATCANCCANNTAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTNCTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCANATAATAATNAAAAATGTATTTCATGGANAATAGTTNGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGAC
+
"#"$$$)$%$&&%!!&'*#&"%'$"+%&((!)++!'!)$*#($%$&!'#%")"'()(+'+*)&('(#!#"(#(#""&($$)(%#%&'+))(&&*&*"!!*"&)&*'#$%(%%$$&'*&%%&%)%(+!&")!#%'!"(''!!(')''*$+'*#'*+'!!$(+#+'(&$($#&#')$%&++)"'('&(+(*#'&$&#(*$#"$#'+('$%%+((!+*+$)#)%(%"!++*##&+'(!''*)$&'*+!!)#&&$$(&%'!%#")+%+#"!$'*"%&!(%
@r4378
ACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAA
+
(H)24/?6*B/<,A',77,E=(C2>+C!9C".4E6%)+,:2'.82>!C(8(:8!)=!G7+*.<D48ED'%9H79.C..2;A#;H1F:2!*;1"?E65*)('H-H#G.E+G
@r4379
GTCTGGAGGAATTGATTCAAATTCAAGCGAAATAATTGAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTTCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCT
+
*.AC:@*29*;,#2$@B*F5!0H=,3<&E+*<>9!EAA%=+CH/G,75%"9>+"G#--H6>1F(-?B>-4;4"!G$8D="$<D26?5F->A&=.'C.:&1E&DC/13B.G63978'+(7="B)5D2,A1*(.,D4*21%17-=&$:0%(00&HG<!
@r4380
TTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGNTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTG
+
<!!1'B"8(<?HG4;G-3;0!10E?%=.)!2A9CE;$!*.40!34-8#6)2D?;-A!>F!8#B*>G,!.5H(9#H":F6E,(E/@,95!?7=9./,@9.3E0+GEAG=/&=89G36383;H84A77?*;7@$;F";.76:8A6H(;D>H16C.%F$=G/8
@r4381
TGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGT
+
(*B?07=7>H(!;=;4D&='12>%:-:H@@D&4-6"-A1*>1A4%D54.C:&D(EC5".>(@A,!?!D);'>(H&/7:H?(G/?*-A<;A>/&&'<1E$?7C*CD8:?/4:
@r4382
NNTTCTGGGGCCGGACGGCATGANATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGNAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGGAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGANTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGANGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGGTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCCGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCAGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTNCC
+
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
@r4383
CGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGT
+
'>":.$$6!8C$12(.C:9E)F,+('5,E/828<:,$9#-+FD1@$
@r4384
TTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACC
+
;F4C/8:C8D(*112)#H*C9=4"!"6#BE()BA2+&GA7=;>C80'!F-.10731%>E()<@2-*C<8C
@r4385
AGGGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCT
+
34!+A&,,)A"4+-'(>6&(?/9$55&(B-&"F.!B0=90?0."+01!/+9C=&9=1*5&,,2B7--@#F(A'6157C1@?%)4H+-F-5*D/)<-(5B=@9D$"+?9-:E$5/0;4=.,D,7=DD?"%.7.)A7*;AG=:B$E%D
@r4386
ACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGCCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCGGGATACCCGTCCTCGCTGACGTAATATNCCAGCGCCGCACCGCTGT
+
;56+8-7/*2<7,EF$%8D6);5,H<'50@@;*.*EA./">/,H(F$(3'::!+28"F-(#&E7?&@EFF#2$#9=?@0<635E#%07):,@:).9#4:)CC)2:-&.!+,B44"-<=5G)@$,9;07H8;7FG6.7):'H8;H7).9:0.@'9;//%#;0CH%G1185>>@3E?AC82.)!F+C*)-H42(BA@$1%%25F$'!")'*B3D7H1E#+>&77*(9+H+%.-$=:'"?=+H'8/D%G>2(GG%:9&/E'(8.;7G+>;/4E&C<1:>*8?
@r4387
GATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTNGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTCTTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACACCGATGTTTGTGGGGCAGGGCAACCAGATNTTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGNAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTAACGATAGCTGAAAACTGTACGATAAACGGTACGCNGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGC
+
7@F$2$88+';B"(;6G19FD<C!<'GBC5+.54*<+.(:)GD!<(:D2<F"2+85D(+'A#&E)H,"/7'2'A!$<38;$=":30'-&BG$*:0?+&GG:E9.3G)1%-F@)!"1><>FE/10.00F1%G81#?!*F9BD!'EH!2G"+;:0!C'9;?E2=?.1A@4+#>,9DE?(F"!D,@?'0*/3B1'5/-$-'%!@E);3G5;6H$F+A:3?C6-A$"?H'E1#8F8=<2B:"%>F/9>8;<#H1*2'9+0>6D1$E)07665!,?+&;F>0+:?&*6"6$>HCB6/()9E@E(@538:2D;1,#E($#0)=/8.D;:C&:*HA;D=31;8=%4#?3!'"+3>6*=G0%4"+"&19+F:>("!96A5&4E,--$,0E@F$@/#305:!FG,!B4DD."?1(>>C1<5B)@)761F4,$E)<&!9./"$A2;**,H808.-/1?!'--.*>5.(D35/*@.2'6B@8<89(.*ED$!DG>#<05+B23#.69,!7=$0;0$,1)=#>B'6(!G'36%6:5@(#95!6&-G*62?=/&D"6@?1A9(+'.7?,@.4E;?2D3G5+<)&6(,584?-5=HF)4*7A25B!4DC:">!1&-'88?$,<+4)>,:;,<.=4A8H,?!+,F35<1104A,&*="#,;";82)#</'=,G##HE<=#0+<3***=H-?')EC?
@r4388
NCAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTNATTGAAAAATGGAAAAATGATCCATTAATGG
+
#DB#'<@.7$)D1&5H/+<A4?(75%C&/A(7"*2>'+C&,;7791AC5(6(1&=7*>1#!381:$DF055)*(<F?'
@r4389
CCGCANCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACNTCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCNTTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTNNTCTGCGACANATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATA
+
?G&GCD;-<06H85,#:%#%)96)@)!7,$#15%48!*F:F1%G33'/.179>'("$5:>>$ADC7%?D</H/E&@5E6?'05CB8D?%+%%F:'+:E;?'D)FH@<'A)2F@=//7!8F&:=2=2,@6*#0!!=<0%8%%;;#F28"@/1%;B-E"72-07,7+,(B4&F#7;?7@B='B,G276=.3$(6+DFA)=5H@G%?3A$?0:C)#4#%GG5F#",-G%489'2.1,!3ED$G<=8">FB5"0@E(-@+E31,E80%5BAE0BC",37F7&"H=7)F<F@B=@H8E@=)9>%1,4@8D*6"=3E-'.#'%-4<!9E(>&=3%<.A,/7F<AE>76"G)'8&*DB$G??=AF(HFHA==))*)>@,;3EF7'/1:68%'AH1:;371.C0E?66(9;3<53.E:CG4
@r4390
NGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCAAGACCCANCCAAACCAATCGTAGTAACCATTCA
+
#24F:%?8(79?=AF@8'BE951;H*5E?$%4%H<A')"+.B6D(AGG+?5;6"9'<*0+,8'EB5/@/30=&5&*+(5GG(E"7EC:99=,#,#CGG?',2?6GH,@=AC"*!3'D7(-%F>09-"*;9/F'!H@8"$=@+*<A.:@0F,;B6)=%#/G>#@%&+9
@r4391
TTNGNNNTCNGTCGGTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAG
+
&)!(*&")#($*$&!%)+*#'('+(*)'+"(*)+$+&*)!$('*)$+)$*!*'$!'%)#)%!&%#$'$+
@r4392
AAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTAT
+
=$:)+3?'.9##)%3:"-:A-3CE9&1?:%86(!#-,5+:#?:??5(;&*"+:@69)B:2!#C=01E-,71!A2H/D?4@8"#(6&!C)52=0"FB3"F8-('&?/+H0->4,(-$%!E
@r4393
CNCTNNTCNAGNNCCNGNGCTNGCNGNNNTNCTTTAACAATCNTGNTNGGNNNNNNNTNNNTGNATTNNCTGANCTNCNCANNNCNNTNAATNNTNNNANNCTNAGNCNGNNGNTNCNCACNGCNNTNANGGNNCGNTNGAGNNNCTNTNNNCNNNTTNAANNTCTNTNNNT
+
!#"$$#"!"!##!"#"$"#$!""!$"#"#!##"!#"!$"!$##$"#$""#!"$"!"#"!"!""!#$$!"!###!"""$"#$!!!$"##""!!###!"$$#$$#"$!#"!"$"$""$"!$!""$##!!#!"!##$##""$$!#"$!$!###!!!#"""###"$"#"$$#$"$"
@r4394
AAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACNCGTCGTATGCGGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCA
+
<<',09B1H-2B+08!>F;3/1C2#00)8;/=9$B&>)G6"7;:<))+#:>/H78=*D2'1H+=#5D>@*D420=9+$5<A7*?H/)(#7H!!-G;-&#>F?&7:EH(:FE2589&95)G!9,+'A0G&0;8?$G(#?*0<%><FD3@)/7:EC32E;20,?=06@=!'.3(591>C!8!-
@r4395
CAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGGAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGNGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAAC
+
A130/8E3?3D)@40(94F7.=7B%><G7<=+HE:C8<A,;2/8?<E804G%+:+/9B+3!90G-H9FD31G=3C<&,D)4.6E&H?-,0*3>8F+829?4$A2G(6"";F5%H76<.+,H?/EG6E#/"3F?91$/:?!7"A8G$.-3!5@**;?5??#,3HE$&7/GA
@r4396
TATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCG
+
D1HD)4AC-C>1%8;6)8A$4!BC@:&=!+"C2!7?.>D%!B6G4+HB542EF/&'0/A-B'2>8,521(H659(=;HF#)20(>7!:4C=1EG72G34C)#/55="GCED*A"H-,G;H.0-7>!$%!"'=?(B+435(,GC&=",+G'C?@(&?!D,+0G;#D"(/=%(*"+)&DA1H0D%A0*!5#)380)G266""$8'2)((
@r4397
TACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCNGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAGTCCGTCAGTACGCCAGTCGCAACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAG
+
G7(($:(1<))0;?7.B/+6"5:8=()836&G4.;4<22.@>;((*&:?(.%3D<48H8FG4>GF2?'():/=%B'-G.8>!2-+:&:F&/%AF$">6&*9&=<0/772.DF6A02F<2-C*#&'3)6&&/3)!%#E&DFF-(#'3$E"F.=.<7><B8%<##+H<+-3?-8=3++48=8B"6.)G#//(7F(B,?>E0)@!:#1=#9G)847DDD30;CH,=)H?C*>E(F!D6--=E438$)<D=(=3*A9.4)D=#>6(G'2HAE8G/F+AE<7G;=%"!)>(16&1AC:&7;)!-G.2G630A2H.H(6=**6D<))C:G-D:1,@9"*DD!GG41
@r4398
ATTAGTGTTTACATCACCGCCAATTGCTTTTAAGACTCAACGCANGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTNCATCTATAATTGGCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGC
+
"!+'$!%"#"&*%#+''"'%+%!&"++#''!$'$%*!#)%#**&""*"%(+&!#**+)*!(*$""'&$"!"&#"#!*('$+&&"($)++))(%*"*(##"#&)*&+#"!#)&('++")$''!%'$+%(*&!)'!&")+#(**!#'(%&$++&$*&+"##)(#$!$!"&!)*%%*"(%+*%$%#()+!'$)"+'%#+"+'#+$&++&*+'&*!!%#)#%$#('$**%+$'*$*%)!%))+#*#
@r4399
GGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAANACTGTTCCGGATCCGGGAGGCGGAAGAAANAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAA
+
5<E4("7@FD/('#7/AB('(DC!>(>H5(65$D*@8E18>#C.!@%.C72G&00&+EH6+-#C=/5<G8<?B:'.:;1#F6=<H!84.!*46#;@<#!.*8FFH>F53FH2"C+4%;7%@F8G?#8@B'%8/0-90B<%+008<F/H<6BH:.E):
@r4400
TGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTGGGATTCTTNACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTC
+
;@?(0HB;H-.G=:.%@*$F"'$1H>63'H'7%+3/<<%..(A>F(HG(+8/<2$9'$D'6'C8?;<!4&G,2>:00/:4(,24B/H.0587>@CCD"&@0F5<?A(-3@<(,2;'0D,9=#=$'B;1H+?!.%>=*7F5?@A<5;@)54F,4#@2?3!<0!<=$5.&C48>:55)6C;*!0::(CF)GA3B=8.!=HFC06859G55;/!+A00)#8AH>:DA@A%9"!B7.*0=2@7=1389F$/'640)7&46F>06,3/.C@C2B!F2&)D-4:D5?1+1/G'CE*##@>0-!1@)G75HH.?G3F=#;8$,-().*@-F6G9+F3/36=6C!31")11(.?7!<7-"$?F8):&0-!:583="?),:D,'(D:.65@G*=#!EA*=D@F$6$4+BB
@r4401
ACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTNATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGTGGCTAAAGCCAANGCCTGGAATCAGATATCTTGCTGAACT
+
B:/$E*;:;<$AEE,0=;2-.DH2+28EC>23:+G6@*BEC,)+D(=?9?02G@=$A;+1+=+>E7,3BF$7"B++;1FA2%"9>FA)+&=@9"D>@7="92!;%*>@6,E-%.E77,/GE2C$F<?+,1>3%/D@CA:4&7==+#GB+*>,,F.)5+@$D>,
@r4402
NGNGTNCCNNNNNTNANCTANNNNNCCNCGCTGNTNNNTCATNANNTNNGTTNNAGCANGNTNGGNCNGGNTNCCGNNNTNANCANTNGACATTNNNCNTANNNNNNNNNNNNGNNNNANCNNNGTTGGNNNNNGGTNANANTCNNCNGANNNNNCNNNGANANGNTGGNNGGTCANNNTNAANTNNNTNCATTNNTNNNANNGATGTANNATGNAGGNNCTNNGNAGNNTNTGCANGGCNNNNAAATCGTAGGCGANGNTTACNGNNAGNNTATNGNNNACNCCNTNNAAGTNTTGNANGGGGCCGNNNNNNNTNGCNGTGCGGANAGNNANTNCNNNGANT
+
"$"""#$#"$"#"##!$""#"$!#!$"!#!"$$""!$$#$$""!!"$!$$!$$"$##$!!$!!!!#$$#!"$!"!""#"""!#$##!##"#"!""!!#"##"!#!!!!!##$!!!!""#$"#$$#!"#!#!!"$$#!"$"$$"#!!$"#"!$#$!#!#!"$"!!!!#!"#"$$$!$"$!"#$#""!!!$""!"$##!""#$$#!""##$!$$""""#$!#"#$##"""#$!""""!#$#!"#!$$$$$$"!#$$#"!!!#"$!!"#$!#""$!##$"$"!""!!#""#!$$!!$#"#""#"$#"$""!!!!#"#$!#""$$#$!"##"$$$#$$"#!!"#"$$
@r4403
NTTGTTAAGCAACGCGCTCTCGATTCGTAGAGCCTCGATGCGTTTGTTTGCACGAACNATATGTAAGTATTTACTTAGATAACAATTGANTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTNTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGNCCTGCATGAANGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTA
+
%%(&+"&!%"$*($'$"%!"+)**(%)"&)+%'!##!&'&%(*'"!!*&%((&&)'(+#""$*$%+$$$!*!#$($)+(+#''*'#!(++#+%!+$*%&#%!')(&'#!%!!$&$+))'"+$&(+(!&')+*(&)$(&%$#$!!%("%!#+*"*'$&$)$!)%%()*!$#%'&'"+#$%)"#+'&+%'#"*!#$!!&!&("(%%$+&&'!')(!*%((&()!""()"('!'*"))+!#)!)*)%)!((#*("%#$""%&$*'#)#"(!+('##&'$)"&&'*(&"+($(!')'(#%*%'+'##')&'*"#%'!""!!()"$)#(%#"%(!)$''#%"#$"+%$"&)"(()&(#("'&'$+!(*'(*(#$#*"*"#")((%(!'*$'*")%!($#*""(()&#'+('#+($*&!(((#%*"*+&+&+%)*()+%!&#*')!"#')#(!$$+%)*(
@r4404
AGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCT
+
/>!G'9?':!B8D22@#-H7(/2@.F'$>.-'BH<BA1->CG1G%)E2<"7D3D.)E='/?A66/'%73(%68(;=1;E7G:')5E/8G!C:#<?B1C$)7)+6:"=2$1F3!6'0$>1B1D$45D4+4?&2E2,&A+G,C>BD167$4$G"D5C3#+HC89!'=":(G
@r4405
CTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATGCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCANGCGTTATCTTGGTACGGCGCTGTACTGGANAGCCGCAAGTANCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCANATCCGCATTCGTGGAGGCCGTCGGTCCGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATNACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCNAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGC
+
>+&AE8>H3;333E/41DB>/30?H,+,;E!*/'&;:1>@.:.F0";8:'48$D@7<8$0-'E79',F50.+9)@"!7$3DF+A'>7%3/+"B9;&5H?@!'C!6A89&1?+B.+<+%A!?8@94CH*7C#G2(5/DG-)&HF>DD2;D89G")<6/9<?0B(.*'7F@(2('".C>5;"+,))($3-D&*D;.7&*)?/5)0#B892/7F10:23.325(#9DE%?;CB8-AB$%7B#3-A-,,6&.1,(C(%5">'<>1G43-<>*-G'348D+4,(#@?(173G9#+;F#-(),G"&)C=2,;=1;C1G$$(7:=/D62H*#)G!=F-D1F3!'140:E#%A(G+D=91HB.9@7@/4/36E71!2@19.-&>!<B-8E"*-C;"8*=CHFC,8CB*A1?'&$2C,G85F2)-"7H,!?E5G):;$$?FE53>3.-7*.HG0%8G8&</6*"(6!-.#%'%7(:5.&):31B/19#2'E695A,/;!<>.D:<%+!@37EA.2:13G,8)10/!%?'<D"6'@F:61*='C3.@"8&4+"<;?958/12,@9C9?B<7-+@!7#$(@7/5*('9*#2#30+9$4(H@B*470,H=,&)&%#B9E=G-F@)>$4?>7,0@-B&C8?9'7B>*6#+G(,-9#E1=-839$:,!076%1'8GE/>*!+D2C+C2!A/02B%@-H)C0/7."')><:(.:4&!G9=.EF4=35D:1(8HD(0H'&5,"A$+ED&7+4E!A6<4$03?H14(1C"AD-#!"--7>;1:6/&6C881F68C3=:1
@r4406
GAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGNCGCAACAGTAACCAGCATAAATCANGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACNAGGGAAGAACGGGAAGGAAAGA
+
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
@r4407
GGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCNGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTNTCCACGCC
+
)<;+69A%H?*<",0$B4#C%)E:.+6$+9;?H<-(,05/.D/,8=A4:HE7.H=0DH'1A.,BH7.4)+2/-((<06C4<+%9A*5!"=*@*733(5HE9:0#CH"?'"G&H-7)D1C.''%G9'>+/AG(.H?;*$@":0
@r4408
AACNTNAGATTCGAAAACTCGCNTTAAAGCCCCGCAGTTACTGGATTAAACAANCCCAACAAGCCG
+
)#&''+'+))&)&&*+%"'(+'+'*%*%#'&"(!%&#"*#&&!%'#+#"!)'$*$$+%+)%$&%'%
@r4409
NCNAACCNNNNGNNNNNCNATGCNTTNNANTANNNAGAAGGNNNNCNNTGNGNCNTNANNNNGN
+
##$$""!!#"!"!"!!"!!$$"!!$$""#!#$!$"""$$###!"#$!"$#"$#!"$!!"$$##"
@r4410
TCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGACATTTNTCTGGTACGGAAAGTGATGCGAAAAAATCAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTNCGTCGGGCAGTATAAAGCCGCCATGCGTATGCNGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGNCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGA
+
?)D:H+AC))#3B1-9/3&!,*?0B9,:'!",@4!.0,H/2A4:A?6E:%1H?H9-EE1#*-8.1"A,3E083<8:7<$1H.&16!9E/-$-F/1-78D0=#<BC=(!F3H'/D:(.*45"",@B5F7C5)&40%8DD.@&-5-F&G@G<H44??<E:A,@;C455F-&1G!B$?>&!:@8H7:1#>"5(;%!>A=.1:68#:?G48/-&99:+#=,G%25,6$$$&=8*H>'7(3@3F+B$E$394.$!(5F&#*2F*0-/@?>#$?90:/?)404$=.27$D;/*-</6:FD4B4C79#*8D,,D3#3-*9;AD/EA,,0%'+"9"@FGF:9,90?H#B(,+'!=DC<3)4EC!.3A84#44"ED82H<+#(&5+8?*8?516A6F%-E1:6$+?!9F"B62""4;<*,H/40,0D13#E79=/#*304F>3-D;C.>7(2G1F963D<D<6A*&2760;;$H1?C.5<3=,HC;0>>F1;<B=1F4
@r4411
TTACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGNAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTNACCGCGAGCACANGACCACCGGTGCTGACACCGGCATAGTCNTCATCGCAGATTTCAATAACATCGCCCGGNACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAANCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCNCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAANGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGNTACGCATTACAGGTGATGCGCGGCTCCGTACCGCCAAAGCCNTCAGGCACTGACTGGTCGCAGTAGTGGCCGATGACATACAGCGCCCATTTATCCACATCCGNCGCACCAAGACGTTTCCCCATGCCG
+
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
@r4412
ACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGAGGNACCNANAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGCTCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCT
+
+&%&-<>095(.<7)/,.3396.)-A!?-CG:8.287,2,BE$<31+74/;F<"$!'D=3,))@F0!-2)<G0./,B$("?4/=-7-(==D;0E<,C!D5GB6"6+)*."BB&47=(=&:&@EF&A.=857!-+4?G+G*.&:+F'G24&G;938?AEH:8@>;/-&47&,;7;9;9F(.<?;HAGG3>:!<7
@r4413
CAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCANGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATC
+
2H-$G,,61;=!$7G/*(5!@.892:B@)>8&?H359-=C.%G3#)>?8;/;A*=/2D(*-'0")G%'%$?/204-,;3,4GFB>-$53(E:0=:3EB0?7)4?$4@$55!3.DC6#H<:),E84(*B%08$==#-E(F&,&?,>04<0$E.4=!#AD
@r4414
NCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACNTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTA
+
$BB62&5<0@'*D<)3!!<89H?56$@$D961@>$"BB/AF,#2)C/A;5$"1$FEF&DA?%"$!@8!C#H-/,6):42":!#EE<-$8"4'6DF&6:1CH2@-9:E+6B31,<=H84C=(6*H!"2"487((-2//3.%FFC9%8!1&9ED!#.>%D96*.$:?#,7&+?;4*1.69D.!CE%'&,(#"*4B#32G@"0.8&!$E>04/E(
@r4415
GTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCCATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGNGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCNTGTGCTATCTGCGCCCATATNATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGGTCTCCATTCCATTCTCNTGTGACTCGGAAGTGCATTTATCATNTCCATNAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGNTAATAATTTTGCACGGTATCAGTCATTTCNCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGTAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGNCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCATCTGCATCCTTAACCCATTGACCTCCAACCCCGTAATAGCAATGCGTAATGATGTCGATANTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTA
+
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
@r4416
TNTNACAAACGTAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGNAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTATCTTTTCTGACGTTAGTNTCCGACGNCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTNAGGAATGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTNGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCCGCGTCATAATTNATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGNGATATGTAGATGATAATCATTATCACTTTACGGG
+
$("!&&(!*!#&(%+!!!$%)!)(&+"*$*"+&((%$+*)$($#!%&+!"%#+$($$((#!)"(#$+$%&+%!($)'$*(&''!(&)&%"(*""$*%)))$%")'"&")$)%%#$+$#*"")!#%$)&%&#))*)+"('"%!""#'(*(+%#!$&%$&((+$++''+"!)("'%"$+**#!!&+!%'&*%&!+$)%+++&(++'$'))%*)&*%(+++)$')"+&##$(*)&$'!&''+)"'"###+'%(*)%*+)*$)"%%$$+'(*"&#(#&'"$*"+#)(+$&(%!!'$#!#*!&"&!&!!$"*%(##%""%"%)#))#''*#(!#&)(%!*$*'+!(%&!!!"'&#$($%+!""!!$#+'&$'(*'%*""*"%#&#++(*'"!)!*"#'$+'+*%&)')'$+&''&*%"*'#*"&#*+!)"#((&)'"('(&*$*)(!%*+**#(*)+%%)!+()"*)*$($(!!#"!(&&#)"&&%$+#'%!)"(!!*!!"
@r4417
NCCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCTGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTANCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAA
+
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
@r4418
CTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCANTGAGGTATGCCGCATTGCACTGTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTNTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTNATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACTGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACGGCAAGTGCGGNAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGC
+
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
@r4419
CCGTCAAAAACATTGCATTTNACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCANAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTNTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGNGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCNTTGAAGACCATCGGGGTAAAACCGTCTATGACNTGGCTTCCGGAGACGCGTTATTTATTTCTGAAATCGGTCCGTT
+
1@'G'543.6C4B;0)#-5GFG-422C31'6@H'80C'!*5:56!GA!2+'-?(*&-HG?-*!5>@>-F6"+@CFD,'5+=6?81G/0239+=''.!1C<4A?,?62,G!9(2;(208$/D=AD'B"('CH!":+04%5-$=@A0.:@>F/1B1#$2-EH#".D!5B32)6!EDB24G$8"B0%+/C.?7BA>0B;1<%HHAD><;3(D8%0!273?G,?<>?*D.$)48"6G>13CF8B8-&@/C-+,89C)=..=!7"F:96.1,(37#4*$.?.'*DE#.(C!5<CDD0>46=0B*A9>G5/AH*'-!#1#H#BE:
@r4420
AATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCG
+
HA'-/E+-317'H"H-3?5$$@@2G$'.0B'8=59+C/4B!+5/.%)4$8%9C$,;;51H1./C#!;-B9H0CF<814?62,A")-"5./G%(!2-<5&D-9A7+E4'&4F8)'B7>'20:3;(%9))F?B%&)4B/7/$/=,+H.%)1A"(';3%4317D:<==2=@2>F<!?<)B)7.D-)@7D!7(##CE"2@(7H%8%)80'6A#
@r4421
GTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAA
+
4:=9H15B"&<-@-E1048FG==AG8E6@2:3"F<G=:=8(*GD1H::5(.<&7$/+>'36--?$2(C1A!3E""6.HG%>G('@B11=,:"@+4<#C=E?D=41=0#BF'4;#40C%#(1+)#0-B45#=F(*$4?,';;3%4$,-
@r4422
ATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATNAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGNCGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGC
+
G5405&'))33"7#7(<1C"(FD"*$.203>.-%B#>5!C@):173<<;G/D&=BB(DD<*9(%:*>?>:$-?%4!@,4BFB0.%@#EBD$@",>"H3*9.A!,+G(EFC#?$?*9H)<@8"1B=0/&3-F243H7E.E<?>:HA"5036(6B:G.FBC%EG9%D:GH1B377G.DB$5$48/'A/*6BF"(+8+(C40=G0,8'#
@r4423
ANCTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCGCTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGANCGGATTGCCACTTCCGTNAACGAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGG
+
$$+!("+%()'#$&(+#+)'#(+##$('**+&'$+'%))$""&$'"&%#!!)%"%%'!+$"#+#'!&%!*+&"$!)%)**$&$("!))%%*+#*&+%)#!"")(+"!++$()$+$!)''#!!&*!""(%'+&+"!#"%"+#+#+#(')%"$)'$'%!(&!$(%##&+!!""#'&$%)!(!"')!"(*"(&"(#+#(%$+%"%+$#%"!'!!#)+!&#!&(%$+#%%&$*!&!'%"*(#()#"!#!"!'*'"'##)
@r4424
NANGNNGCATATTGCGCCGCTTCAGGATCCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTACCGGGTGTTGCTGAACCGTGCTGATACATCAACTGCACCTGATATTGAGTGGCCNGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGAGTATACT
+
!("(!"*+&&&$#)"()'&("%!&!%)!&#$&($%+#"'!"!(%(("*&(*($#$!"&)('"##(!")%+$((!&++&)(!%)$#*("&+%*)+%(*)#&+)$*)(#'*$+%))**&(%"##"'!)*+)%""!$$+$)"")!#$(*$!%%"$)+&%'#'!(+($"'!'#+'+%'$)%+$'"")**%+!!$&%#&)&*!&*(!$!&"*+$($*$$'))*"))'
@r4425
ACAACCAGAAACTGGATNCCGTCTTCACGGACTTCGTTGCTTTCCANTTAGCAATACGCTTACTCCCATCCGAGATAACACCTNCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCNACACGCAGTTTCCCTACTGTTAGNGNAATATCCTCGTTCTCCNGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCTGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTNCACGCAGTGCCTGAGAGTTAATTGCGCTCACATCGAACCTCTCTGTTTACTGATAAGNTCCAGATGCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCANGCGGCGCATT
+
534(BG=?"%;B*!+99&4/>;CA/0G4H#(&*!E')%/#":360H!2/B%G-2*'D#=H"0CA67+1*448:!A:;4):&BCH-+;=+*G*F-4DB&!0;C#E!05H0/E#,0%:3E>=,"G4@3=3EC.26%>,,G;=;),8*C'1,;5'03,74#&)/&0F;3>!)@!->%73,.?9<8?0,C-8GD3<6<,%,%!//GC$6DC+7H10;6C&'0.*=>=AC4A8E2/&G<"<!"0:&!@>BB2"!'E4.*E(?>G%:87C*+4=++3;+.)1!<C..()?(C'>95E+1638+2@C75H."A=0E,2'G#:4'3*B97F1>=+,135C/;F,@.616>/%98*(9#-#9EF67"5"./3ECFH>(+$*F97$(G6B,!2.C-A).,6;7&7$C:,D!F/97)'@BF%E83!:9<'9/-3#5(>$$@2*61E+H>@+"=689*G%=5)@6*9&%4<(;#35:)G5*A;%&7&>=%)H("#7E;;5'"*%(9*5944
@r4426
GCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGANGGTACAAAGGAGGCCCTCACCGCGCACAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTANCTGTTTCCGTTGACGAAGTTCACCGCATCCANAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCNGCCGACCAGACTCTGCATATGTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGT
+
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
@r4427
TNCGTCAGCCGTAAGTCTTGATCTCCTTACNTCTGATTTTGCNGCGCGNGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGNCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTNTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGNCATGAANGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATNGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAANAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGCAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGGTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCNCTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCANTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCANCTATATGTTTTGTNCAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCAGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGA
+
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
@r4428
TTCTTAATCACCATAACCTGCACATCGCTGGCAAACGNATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGG
+
83C;<42/1*E%-@4D*>20"@<,;8)(E#'93%BEC>1;?@3"1&C+!:EC5*7%!)7(=D:+&E766-+<(F/AD/ADA,#+<7,:16<5!';9;>ABA:>,7;6%7H1&@
@r4429
CTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCANATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAAACAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGC
+
4<>#$8"5B'C"8!"E-/6:=.H;<$B%-!1&500)D+%#159=/)2#D/+-H=.F(/B3.>29.HB=$<6%30/H8CE#%F<HD??73.%=A?F)32"<4.,&1!AH85B/DF102;?7+>&'%G+-(92'=7&*G-*"/6'8E!$G$;62,0!3%,7&H;%DE&*.AF"*2.#%7:!@/8$/3+F7"?+<3:5/,H$4D:5<&CA#:5;1HEBC90$3!@>H7C34,D6&/57"&(%-7F<D5&=6197=FB'=.;?51)/-A?4C.2<50G?%01<'5(!:/E,%D:F.DC>@(%E*%:./,&H&51?@E5"61"3.D0?3"+&,&@9(F&*DB&#="@<.@-11B6B%2DDH$(28!-4,%D?=A$!'#6>&0#,>'/4;-&&2'G,7';;,*#3@C;<!,'5!,'AAC3C(89$82770F+/?5B<</FH+6<:&EGHG=B"0=D&H6A.5(6+<A3*46G
@r4430
ACNNNNNTGATTNCGACTGGAAAGCATCAATAGAAATTGAAATCGACCNTGACGTAATGACAGAGGAAAAACTTCACCA
+
#&"""#(*%+#)##%"%!&''#""''%"'#!%+&$#++!")%'+)$'"'!#+!!)(!"&"%($"*&+#+!"!'***&%'
@r4431
AACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGANGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGT
+
H:%G24"G"G8:>E#<B72@G//'@36,)"BE7!.68B8H9(B!@7F.<3&('8?2F3D99A!C!0=!E95?E!?#D9>DE;6%21#1))
@r4432
ATTGAGGCAGCGTNGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTNAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGNGAATTTAC
+
6B@?E%1G'HC4$8(!@HBGGH6+D.*999!"4$*4??7.9ED!5%%D<3@")>=5/?C0D(B"3C4"(@==*1&?@D=+6800;1$5G!")F&<4:/>#&H96<$B3;(FGE)7-9G.@4*ED(2DB;A77(!G9*"%,*($:6(D,!@8F9E>>-E826<156#;('3G&40!>=4+9)8%=.1,<:%3
@r4433
CGCAGGCTGACGNTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGCGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTNACCCATTACCAGNCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCNGCAATGACCCCGCTGATGCTGGACACCTACAGCCGTAAGCTGGTTGCGTGGGATGGCAACACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCANCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTNTTACG
+
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
@r4434
TTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATNTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTNACCCGT
+
?&%?@/3C*A!:#<&).D38B021FF6;&=59@<G+9+6-8?&A0-5G"3.9&'<@.:@85(7.:2E2#8C+@71GHB;!>>1E?<#F487E2
@r4435
TTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGNNAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAANGGTGAACTGTTCGTTCAGGCCAC
+
<?$:76@G5F*02(%A>A*$8;#=B",12GC/'$C84%86.6B<3;#+=(=(-/-&B<6>6.<BF.-06)*,,7>,(-0+-H.BA#!'G4@/'5GEC<&8'.)>":E0230H=E1*/8&?4#H!.&G6(6?E;10=/)&.=+.F,FA4634<8%CB)(148<+,A')%H)**#*-6A;79<42<'=HG:GG+@$;@(3A%2/"'/%&#A0@$1%
@r4436
GCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATANTCATCACCTGC
+
-=)1/)./G<6C!F6BD1*)6D2G.FF>0.@D:%$$=?*8:!/CF!E%06+=F'%<+18H%3>4@@FB>?#%1E$G.2<7F
@r4437
ACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTCCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTG
+
.4H%D39'<,76?#,>+:87?*66-#&".95*G'F@!.539<*:(FF0'1H*72!-@3+.;E"9++-C,2>6;./.#!--7-AGGA@@0B<"(3C60,A>->=4)8,=DC2672-!-G8E1>C>?E/'D+H((!.')0E182DAEA$+D3,H,'&7<B>"(!D;+H+H!261#A!"$&?3;7*)A0/=9=+@>3(:)##$":'B4!#7;,4?:+AD.@#-FF"@(-E0<8:(7:@0)D!E6@-G&84@2FE"67(63C<C-9@B8&HG&.";A3*F4-(DB4=+D(<1E"<C-'=4<&=BD2E-,9)H?:#*73@C.28>
@r4438
CTTCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCGGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGNTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGANTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGANAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGAGATGGCTCGCCAGTTCCATAACGTGTCGTCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGNCATTGCAGGCGGAGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGNTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATNTGNAA
+
%($*#%+#''')$!"%#&)(+!*'$$$)%(!"(*&"#""*"+"&#*!"$%)+'$+!"'%*#$#'$*""!)&*'"#*&$#%'+*!(%%))#*(*"$!"&!*(*%#('*"""'+')))#!#*#$!%***()&(!&)(()"!!'+!()*"!"!*+"')!)"$!"*%#)$)"(!&*)&#+$#(+!$#*%##*(%&#%&"')++!*(&#&&*&!#+(%!!%#!)+&'%+)+*$!')!"*(##$("&$!*)*!"$)&%+!(!(%%+&&"((!'+)"!&(&!"((*)&)*%*&!+"!!$)'(*!"'*!)$!%$#"!"'"+&(%')&+'&))%""")!("*"'+)"&%)+!*+!!&"$+**)!!+"*$#$*)&'$!#$$%'$&)*!"%(**)**&("+*)*$(&"'*+!+'%"%"")*)&(#'"%")!&!(#&)#)"+#+$&!'&$*#"&)'"(&$#)'()$'%!)')(("()+##%'%*!#$")"$"(#')!*!!"#!'(("())"$(!*$+'$$!!$$%(%)##%'&)&+&!(""'$''!$&("*"$!!$"!((()'(+)*'((!+()#&)'(#**'$'$%'((&'!*"&$##')"'$!!%**#!"&&()%((!!'+&*)&*#*$!**!+")'#&''#("('"%)'!#!+%("!*'(*"%(+#$!
@r4439
AGGCTGCGAAAANNCGNTNCCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGNATACGGCGTGAACGTCTTCCGAAAGAGCTGGGC
+
!('(#'"**'*$"#*'"#"%'+*#&"+%*''*'('(*$'+!*#%+)("#"$!(+'(%$%(&&$'!%(#%$''#("+&))##)(%!+!*#")*%'!#)%(!#(+***%$$'+&(&+)(*#&"&
@r4440
TCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGNTTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCNTCGAGCTA
+
8>&1.4$#@C?'B#5H2:*/F,$:;(4#D+;=,+?A+<+&C%<2C).=?E9-(96,1$94'EFC>$,4$9<**E*>B=5H:98HHG1()A:F=5"G(.,-%"F3H1$G*(D$1;@5%5E=-9GB/F'$0"H!/A):DAEA(%9#3$&6!7E$(0&/G@G'<$)FA=@(*F-*;D,(=GGE?C?FF#9(4!!)/BE+()7/E,
@r4441
NATCCAACCTCCTTAGTACATGCAACCATTATCNCCGCCAGAGGTAAAATAGTCAGCACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCAC
+
+$+&+!$)(#$))&("#'++)*)"%)+'*$+')*!(*&(*%)%)*#"*$&#*)(*)!&&'"**'%+**%($$%$$!$+**%("""&(&*!+%*''")*"#$$)%%%##$))
@r4442
GATGCNGAGGGGACGCTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGACTTATGAGTGGCGGCAGATAAANGTGACCTGCGCAAAATGGTCGTCGCGG
+
!*'(*#()*&!!')$##&#((+!&"#+$#%&%+'&!++'+*!)+%&*#)+)!"&%*("&%$$('*$)"+'!&*(')((%%")&+*((!#'+(*'$%"!'&#"!+*#&()$&))%%(&&$!'+$
@r4443
TACCTTCGGTGTACAGGCATTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGTAGGTGAGCCGTAATTATCATCTGCGNGGGCGTATTCTGCAGGTGCCGTCGAACT
+
..%4D5'B':(1=34.0'4H*+A5%471!'"=9H=&@03-&9<,8:'3D#HC&-)#9302-0#A1C(H<?G%7G43A(!&:+49<<-<G?.G:07/(D'*8@F9%=H>!:789*7@9"?@G$;'8+,=E(&)%0@%94:C3FG.4G+1-,-:0CB,5<-.A3F,6'FD5!/9$9<?G8.6@AA>F"*<$21&D37+2*>4",D<0;H,$A45/2"B'3G+!93FD/(4D*8F,8C)5,!+84;F),-;1<>,0&::016G%4GFHD#87098,4&,6;E:G+H5.!=4&2*6?,6.+(!-#<@=!@C3=9,&+*B;!C"$69=E3,1(&4$!/;D@'*4?E4">H4;,"(=51$&=+"+4D2C142/E5&:FB.D&8$(C2F4$CG<9*;=(*:@<BG,478%5
@r4444
GAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGACAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCNTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTANGGAGCGACNCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGTTCATGCTGCCCTGCTGACGCTTCAGGCAGAACGCCNGACGCTGGAGAAGCAT
+
0*!8#'79@?5FA2346'5-:/;=)-GH)85'2,*77B7/9C'A=%C9&4!(94(27HD"<,50%3A."$G6=H5!(%967!,55/=,/%C.?FA"&:0+3G:$8@2.B;A)5C@4E)05:E&-#<(@9/-D&?">(;5#?BA!%:?)-@!#B=)A)F66!+8?-"HAD8%>9>52"/,/5%!>$E1BD'A4H+D47=F,&)9582H0?311+8=9%C"0E/45:G*8;<>)C<4&HB@@5(+9::@*4
@r4445
NNGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCC
+
*%"+"**(*++!$!((*"*#*(#!#+#!'&*!%&)+"+)!&'%+)$$)$""#(')"+)***"$$%'#%*!&'$*%+#%+($"$!+"''("%"!&*)!$#*(*#(&*"''&((!%$!*$%($)($
@r4446
TCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTNTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTNTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGAATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAG
+
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
@r4447
AGCAGTGACTGNTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCC
+
-A2F%-$D5)!6!5-0:*A7>,#1.<-F+$3.:D#&7$)6F7-8?=9C,/"G"1-2"<=7>)@<9B>E==)'
@r4448
GGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTT
+
;081;15D@=<F!*4C?E5&&#3:(0G7,>;+G"+8=/%H3$
@r4449
CCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCANACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTTCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGNGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCACTGCGCCACAAACATCGG
+
>=,A3A-0EHFF&7&019+5;/@)35;$+!'?.4D%B.5%?2>F25-03"02<E>3B)*,.B6,0::7'%*097>6),";8B.4-*.1F.;0/@G>-7+B<!H%'&8%@00F>C7A.*<42:*-)2#D7"&278/9==/CAB1G0F0=7CD6(6*7".G1<.EH*GG1DG<5:622E9=G9&6,,.744+;4*B,F'6/2.=A?*)7C%(?)>"0@3"5B4,:0%8+D2?9AFB58(G<:1'G56DC
@r4450
ACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTANTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCNGTGGTATGACCGGCATCCTGTTTTCTCNCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTA
+
29GD''?;A'*D8%5G3C;"0AA!(('36<D0(#<$;(@=$/*H:AB(5/-D=C!B-2/*H&686/=0-.59!&?B*E#!A0-7(4</.4.+3*6@?-<4@(7<9#6(D"E'720%5#120GEG*66)B85F1)#&?1D+B#1A=F$1,$1&?*C%9+@4HD(GE'#08!5(?"?;E?#9F8.7,$C87@<D'A;$"H(GA3@D:>=F9,46'5GDB05G?:F<>.;(62!78B=DGD;8:F7C<>436"#'.CF?*-/%!&@4'844'%/$F)1#,$>")B)<CB@)$1-<,&"4(B9>,317='%E4H&E0<0)"4173$E52(&@?*8HE>'2C/
@r4451
CNGANNNTTGGNNANTNTCAGNTCGANNATAAGGCTGACAGCCTGATTNCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGNATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTT
+
(")$$!(*"**'$'"!$'#&%+)#"$%#%%&*"")$'&**(#+**)$+$*&"*!')%$"%("*()%%"&#+"++$&*+(%%&"+%$)#&%#(+)"+$$#*$+&#$(*#)!%&%+%'$')&!+*&(%')
@r4452
GNGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGNTGGTGATTGCACTAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGCGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAANTCACTGAATCCGGGAGCNCTTTTTCTATTAANTGAAAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAANTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACNAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATCAACATNGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTNTTCTTTTNGACCTGCAATACCAATTTTAACANTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTG
+
#&+#()&%"%)$')#"'+()!!+**('#$*%(*)$'!"+"$$"!+'+!))+"))')'$'("((('###'(&#')*#(#(%""!&#("&'!)"*("+!''#*!!'$"()')#!!*#'&%)("*#+*%*)()$!#&(#)!+(*#+#$*+%%%%(&*!"+'%!%!*+)('&')&$#$&!$('&(*")+)#!'#"+(%"'!*%)"++++'#)')%*&'&'($**)'*+*)%+%'%("*#(!$*)+!+#+")(')$#+!$)'$%*"++')!+)''))%&!&*%"(!'(!*"""!""%$'*!&!&&&')%!(('&$($%)$!+&)#*%#("*!++&*$+$'*"'!%$!*")#%'#!*&)"#'#)&*(!#)#*#'")#)+"!&$&&#&(%$"!$'"*'"'#&$(!(%!'$"')!#'"'$('%!*(%*"$)%$'++"''!+!+!'(#'"#(#$+#&)&#)(*"*"'&$&%($$*&+#*)"$$%(%"'$##%+'#%'$''!**"'&$($+''+'$($&)*)+'''!(#"(+)$%#+"#+%+)+%%)""$(%$"*%"&#!'*$%*'%)&#'%'&))""("'#&!&)$+#+%!)&"%&*%*+&&'"!$#*'""
@r4453
GGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGAAATTGATTCAAATTCAAGCGAAATAATTCCGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTNGNTCTTTGCAATGNTTCTTATCAGNAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTNGCTCTGCTAACACGTTGCTCATAGGANATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGAGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATNTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTNTGACTGTACGCCACTGTCCCTAGGACTGCTAT
+
!#+''+()+$"*+)'+!(*"$$)+&&&*)*&!#$$$&&!%#+$*!#'!**!#&+%!!!'&"+)!(($&!()!%('%%)#"('&'!))))*$*%"+"+#'#"+*'(#)%')#'"'$"+$*")#*#+*$&"""&$*#+++'**)'&*'%+$(%%!&++&*!*!)$$!(+''#+$%$"+!!)+*!"!)$()#"##!&+#$#*+(&"#$&*"#$%&$(%!&*!"'+")'')!"$+#***+#%%()***&##+!(%&$'#(#*+&*$#"!)&*"#$$+$+!!**&%$+"'*'"*($!&&(&!&'(&($(!(*)')&$'#"&(*&*%#''*"!%%*'!'$#$*'+&'%'+&*$'&*(%')'!##$**&!*#$&&*+*!+($$'%(&%(!"'#)"!#*!#&%#'()&#+'$+"%'+&+('&&($$+''%!*#$&((#$(#*""'$%*)+)*"($*++(*""(&'(%"&+*#+&*&*"&""(#("$&!$'#!$+!#$++%$%#+*'&&*#$")#"+")###'+!*"(&(!'#$!''((%#%#*'*"#*'()(%")%('%)#"!&#('+&+'(%*!)%""&)&''#))*%!*$*)'$+$+"#)%'$$+&+((+#+!
@r4454
GGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCC
+
9335@;3>':,E<&30)4:-)!;AFH3/%2""9B3A$-&)<)A&!0A"3@)#/C(-,)*1:++(23'>=>HB')(,#$(&;@8/1,#&::)+/DE85G"F:-)<)*;D7-&*9%F'@*;..190C>="+=F'&:+A86<#G:A-ECB8?/E%9".E@&$-(><FC"F851?/
@r4455
TANCTTCNCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGANAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAANTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCA
+
($!"*!('++)&(&!##+*%*+$)$"*(*$%*$+%+(()"*+'#"(!$&)%***&%'))!!&"*''#)$'#&&)"!)&+(+#(%$&'##)(&')$!'++!"!%+(*))('"($#!(%"+$#'%&#*()$'$&&$&$'&"+&%'#*$'(*#*&""+**&%*!"))*)&%!!)!&$""+$##$*(#&$"+'%++)#!!")"%!$"!*(')!+'%)(#%((&"$"&%!#&%$***'"!$+$+**(
@r4456
NGTCATCAGCATTACGTCATCCTCCGTCAGGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCNAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCNTGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACGTTCCCGCAGAAACAGGCTCTGCGCGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGNGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCTTGCTCAAT
+
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
@r4457
CACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGANTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGNTTGACAACGATT
+
283.&7':E:***#&BF28*744$#;',5D1>36?%!*27E5*73FB59>76BE/"$',8$(0$!(A?$2C>@?*052":BD2D?11?A2?3C5.%7"G'H*:'$&GC0.$96@;-<8A1;F/8(:!$='/,H-:=)'"G/5$/+20'F(?%7''05C?--D>F7G?4=4F%A276DD84>&F)5>A-"F2%?)-?7?55GB;E:EF2F$7*=88)=BF+(0-?8"D"04<3'F*F$?E"-5"*@2C!0*;<8"/<.>"5BG7!@&$5G@;>8H1<#?DA%H$;E&)C5>7(@?F(+A"C)?G"@';5>A#4F4A7-;;%#;HG@">%-:'H,4E+9$1/!$!6"+4A9$FHC
@r4458
ATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAANGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCNCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTANTGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCTTTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATAT
+
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
@r4459
GCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTA
+
B8H-:@57*23=('H2%1/#/*D-2!(5,!01H$0-,H$D+3::D4E80#E7$7:<)
@r4460
NTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGNATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGANTTATGTATCAGTGCCTAGCACACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAGTTACGACGCTTATCGTAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTGTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGNTCGGTGGGAGGTGGTACAAATTCTCACATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCCCGCTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTNTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTANTATGCAACCTATNAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTNNATTATTTCGCTTGAATTTGAATCNATTCCTCCAAACCGCAAGAACAGCAACATTTATTATTCAAAAAAACAA
+
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
@r4461
AGCGCAGCAGCGAGTAGCATTTTTNTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACANTGAGTTGAAATTTAATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCC
+
<#A.')+E'8B;&,;(.F)H/+:A6047940@3?/=+73;&78!*.A#;B7,"+@<*6E#2G(B8A>+EBG-,4-(52$<*E)-CE*.:3A9H!)=4D)#(F0!.%,?7AC5A7)7*:"#44!2++=/H#0=&G.(0.42G3>0-:@FB14F(3(E&GC=?+%;9FA50
@r4462
TNNGGTGCGNATTANTCGNTTGTTTAAGNGCANNCNCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGANCGCTGCGGCCAGTTCATTCAGC
+
%$!$*$!)*!)**!)'))%'#'*'&*!#&'"**&$!(+##(%!%&!"!$%)!*')"")"#"$!+!*&&"(!))(+(!%($)+!*%"""')*&%%&%+&
@r4463
GNGGCTGATTTCGATAACCTGTTNGATGCTCCATTGCCCGCGCCGATGAAAC
+
,"23$5,;<21A*7>)H+H6C!?<7$/09D$5$F+"G=D7/0=,5)93>E?6
@r4464
ATCCNGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGNATCTTGCCGTTTATGACCCGACGGTACAGTNTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCANGCGNTATCTTGGNACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTANTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGNGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTNAAAGGCAANATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGANAACGC
+
(*%((&%*+()")&"(+&+$(!!$'(')(#+'+#%+"%%#%+)'#%#&!%(#&'+#+()%+&!%+($$"!+((**$$))+$)#+%%#$#"("%%*&+%%+!%+#&%&%"$*$#+&'"%%)((&#'+()"*$!&!#))!)"#&%%!*"#%)($*""!'+&$##!"'+*!##''*%**!$!#+*))$*'$#%*&)'$+$'!!!#$!#'))'#"+!&)*('#"$*+"*+###')**+%(*&++"'!+('(&((%!')*!**)"'&('&(*$($$*#$*!!+%&&"#)+#**&%$+'$!%('+#&'&'!&('!(&&)!*++#&&)&"'#!%'+')'&"*!)+$#)&()&$$%$$#&)!$+(&"'+%$"%%'&#*%%&%%)$+!'!#+'&)&))&'*(#&#*%"$)
@r4465
NGAATTCGGCAAAACGTGCAGAAGATACAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACCATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGNGCTCGGGNATGATNCAGATTTTGCTACCACCNTGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGNAAAATGATCCCGCCAGCCTGACTGAACCGACTCAGNTTGGCAGGGATCTTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTTCCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGACGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATGGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTAC
+
"#+&#''%*&+!'(&!$!($+!%))('%!+"')&!"#&(!$#&*$)")%&*')'!%(%!'*'*)'(&*'!+#'*$*%%+'$($!'#"!&)'#!%+%$&&*#%%'%"$""*&&&(#'#+$+)+"'&"$*"#+&)%!***%&")'%*+!''!#$()#*+$!"&(%%$)!(*%+&#'#$"#()#"*%%!##&(##*++'&#$+&+"%&)++(#+!%+'$!'#$$"'($)!(+"'**"(!%*&*!)(&$!%#+"!)$$""!#%**""+%$&&)"!##!$##$#)+*"'%$(()!$!#)#!&#**%")'$+*#+'#%"*%"&$&+!*')%#%)&%%!(*&"!!*)*'$&&%*""$$&#('"&*%)"')+"!+*+#*$$*"*)&*)$)")(*&*"*'$#%#$!%&#'&!&%+$&'!+#%%!"%)%#%#'('""#!*)$#%(*!!*!'##!#(!)"#%*"#%%%*"!&+*")##&"'$(%%')&!"(&+#')))!)%)!$(!$"*#!!!&!(&%$*)&)*%!&&&#!!!+)*(%)###%)#%&$+('+'&'(%&'#**$(+&)$+'($$$!%'!+%)+*#'$'))+&*'(!&!"+#$(&*!*#"$*#"%#$"("*(!#''(*)+)$'&$)#')$$&*'*$(%+%(%$$(+#$!'(#("$$(&()"&&&!!+(')&!'!+*+(()$&#""''$()#***+!*%%!!)%$*&$")'+!%%%*))'+%%$#%())')$!)%(!%("!(!%"#*#("!$')#&($+"$$#"%''**#!)!'!!+#!$!("*&&(#('*(!+'#*&'"$%&)&#*())(%"#%!!$'%
@r4466
TACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCNACGAANTCCGTGGCTATNTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAAC
+
%&!#*$&%%*+#!")!*%%$***)&&%))'&$%#()+#&")++*)+&'$#''*$"'(*$*##!'#%&#$("!#$*+##!('*'!#!+*''"&*$)%!$*(#(#$+"*$($+#*&"'!!+*&()+&+(%#+"'$"!+#$&$(&&'(%"#!"%%('"*(&!+!))'&+)#%&""(%)%%#$+'%!$)!*)#*)*%#%#))'*)"%)(##+'+*!""+*$&%$$%(%"$()##+#!"()+"+%%!)""%&'*+#+%!$$#$+)!("&))"!'$*+)'#+!(%"'(%(*'(&&#'#%($$"*#*$*#($%))'+%+$+&%'%"))"+&*(*+&+&
@r4467
TGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACNGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCTGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGT
+
>4<5?+:%D<$6/"&/*'A3?1:B?)?$2'*#G!E;5G,/?*-7/0(E'>A:/1D0/":)$B*(/=;-6AD7G!B$G%8.+*:#(##5$1&;>F<,7?H4(0!2!&CH"+'&4DD-)"5:(,:$'>0,&A9%-?C854$09G>>)#/?9(1>!>9&))=+;$/A31B%D<$%@EE4HF$%B19):5/.H2.H>D(0:!%G<6"%7+,)($EC9:*<*9%%)=5C!+*5EB).7=E":?3+%*2*&;(-5'##A-8)"E)@D'@F?DF3(/:-,8AB"08"@"D2;@.:/)")F+2/.'9;.2+3!7;?>9@%"GEG1*/#0<C)'28%DCHAE!C*F&A99-5D@/GD>>(=.4(9112C#81=?B&A072C075>F;D+1#>A+)/49$#3.B:G.2*&*6=$,C3#+071E2-&AC.!626"D=.?B$+)=EH:<'(=#4BCE3G.-&<HA
@r4468
GCTTATAACGCCGCATTGNTTGCAAAAANTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAA
+
)+./G$4%(3C%?@'>,#@&8E76G=06:/05.;+$(DF,E4*-@CBF/!E6+=.F).718!9;(',25."+6B+#,1:8)>:-!&G<-4CB0
@r4469
ATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAANCGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGT
+
'3@812,"7!!5+*59;-F6F2=#1!'/!=4#?G$"82"%!:0&@=A6+-%0'E=.-5HHH>#!H*D3<3/:/712AF>#/$0/065=40#)H,/-&>@/B*=F/1--76F@,$3.;.)6(C.?&G=&0C.<:584<1D0<70B"%*/7A$$?H)C%:@C8/&9)'DEG#E))<",19B6D'F>$9H>@6<EC?7-3&3<:(A9D$*E*>/#=D5=F%8@/6$G,E#=!*:E#@8(;4A7A$C?4#@7H)$EG;/)63,3:D&>77F'-E/G6/99=(,$#2./?>G)605A0-'@@F>
@r4470
TCTGTTGATTGTCGCAGCCCGGATTCAATTGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCNCTCTTTCTCGTAGGTACNCAGTCCGGCTTCTATCAGCNTCACCGCTTCCTGAATTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTC
+
2+$2!!7(3<;H.-+E'2E?,>D:4,7B5%.3C'DF:34A+$",08G50=4."B(9BFC':%7#/597-:@FE%F:"<D1)+6D%%+"(#5$B&2#(D@@=296=-&:#&B0A!=:E@C-'4<?7BC%7&8%5:5/%D<1'0,3,>D9'&#E2#!.H%@-;,"'208?<>8C>905!,'%A45>!A>!BF(D.74'30F,@G#"9)=E;AFHE;."2>&08)8&G7A:D3*55?=!G>A4G?6!E;/4:#;3A3?*D<H+=;3
@r4471
CAAGAAGCCTTGAAANAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCNCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTNATGAGCGCCGGNGTTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGNGCGATGCAT
+
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
@r4472
TTACNGCNGCGATNGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGNATGGCTGCNTTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATGTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATNANTGCCGTAGTGCCGCGACGCCG
+
*$)%#*(&(!+"##+!%+!'#!$'&+!!+&$"('('!#')%%'+&"%)'"*&)(**!&%'#%*#$#%!)"&!((#')*(%"#!%#+%'!)"$$'&++)'(("#%'#')'&(&#%*##'%#')'')*!*(!$#()$&+('$%!+&'&&+'$'&#(!#)%#%%)&#')%"#&)!!*'%(!!+"(*#$""%*!##"))*#!!$)%!+%"$)')'&'#')&"%*#*+))#$!$')(#))*!'$+$(&"')&'#%)
@r4473
CCTACTTTATAGAGCATAAGCAGCGCAACACCCTTANCTGNTTGCCGACGGATGGTGATGCCGAGAACTTTATGAA
+
:'?(&6-9H)-F93B74,8H1*G)@@A9C=#5#E=&.<&#F/3:1&G+H/GA.'0BF3#$#)%**%4+7A*0="+G
@r4474
CTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGNACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCANCCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTNACGGCTGCATACTAACCNCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAANAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGNAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGC
+
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
@r4475
TTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGTATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGT
+
H:$?-?04B;%%5E14@+1;8;H'#&137C!5/$+>=?<(@<95?G+H%3>>CHD2H$-H;9EB+/,$7/%$)9,<5+7@FB60+$5GB08+#6/F%>;B03A)AGG3;E&!*'F7D/E4-%+F02<.%!9+..
@r4476
NATNGGNCGCTAAANNNNNNANANATTNCGANTTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTNACGATGTGATTTCCGCATTAAGATGCAAAACTATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGNAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAGACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACAGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTTCACTGCATGTTATGCCGCGTTCGACAGGCTTGCTGTACCATGTNCGGTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTAAATCTGTTTGTGGTATTCAGCCAGCACNGTAAGGTCTATCGGATTTANTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATNGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAG
+
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
@r4477
TATTGTTCCATCACATCNTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAA
+
=@42'F;)*=EAD1*;$BE:=,!,3.FF39(8>H?D==<71;E(12!0$$'<E&?)$=H%H2(G3$1&45DHC0$)$#+4&>059;&*/278<1EE.3E*F9>8G,4<BH5<C-#F8G.59E-A(9+&D+G#@7%.H0G>-;3?>*B:C;1'+F4'4),%$(D7+#5"GF#*@3D$-!A?,1)-?<%00A.3H43
@r4478
GTTTNNCGGCCCATAATAATCTGCCGGTCAATCAGCNAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGNGCGCTGAATAATGCTCNTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCANGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGGTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCNTCACGGGTCCAGATCCCGGTCTTNTCGCAGATATAACGGGCATNAGTAAAGTCNAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCNCAGAGATNAAACACGNTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAANCGGCGTCTCTTTGTCGCCAAATTTAAGATNCTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAANGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCCTCCTGTTCAATATCATAATCAAAAGCAGCAAGTTCATCTTAACCCGCCACATCCACCGACTTTTCACGGTAATTTTTTGCCGCTTTACAGCCCAGGCACCAGAAGCCACGCCCNTTAGTGAAACGCT
+
%!#'!!(+&+!#!+**%%'(#)*%"!*$())')$(!***&+*$"%#(#"$%))&($+"!%*#*!!!%&+)'#)$)+*'"!&%#'#"&&"%'(#&'(%'&!')()""""!"&!"$+)+'%#(''*!+%"!!+*+)''+))$"&&!!#"#&$#+$('%!)$*&'"$#%*+'%!#!&((*'$"&*+(*($*+#""$(*%*'"*(!(%+##+$!"&#(()+$!%#*!*$'++%$)!#%"%$(++##&'*$%))!!#'#%&!)!#"))'&%")%#+)"!'%)"!#)()((&#%(*"$(%*))*!!%&%#&"+&'%'))#*!+*$$'''$%'#(*%&"#('()(+"*%(+#+'+%"'&)'$'*&'"(((&##&$"&!("")&!(*$$&*(&""#""&&)$%((%)**#+$&&*!'!'#($#!*(!+###"##!))$+)+!)($*!!)("$)!)$%&)%&+##"%!(*()&"*)"'(*#*$&(#$)*$!)'!***(*&!*+%($%')($(#+(*+$#'%)!+""()$&!$+#$(""'*+""&!&$)$+"#!&%*++!*$##"()$#&"*))&"()'&!)$+))'#(""'!'%%$$#)$(*!#%*%'**))!&&)"%%!)'&)!()##%*"*()(&%+#%!!+%(%+$"$#'*$!))+"(+"$(!'$!)*$"+&&%&#+('!!&!+(*))'!%'%#$%(#%&+&(($#$'$+%&&)*!(&'&""#%%*!*(+*$$"(&##(#(+))%)!"+)!$%&("&#')*((&!)!$$''"+*&")$'"'#$(+&#$+&)$'%("*))"#*$*&"&!()!!!+"(%$#+(($""'(#$#**$&"&&#"')("!"$&"+(%*(####(%''+
@r4479
AGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCNGGNTCTCATAGTGAAACGTATGCTCCCCGGTCATCACTGTGCTGCTCGTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTCATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGNGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCGGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTNCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTAC
+
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
@r4480
GAGNCGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTNAGCCAGCAGCATCAGCGGTGNTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGTAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGNGCGCAGACCGCG
+
+(-BE$5%@*F"7F-C/.7@F#6'%)9E(D$E9A,:F:467!HG+0-":8@0),%,HFE18%6'0/+BC):E/5;%.A0=A)3H'10&AF>@2?!9#2*+AH6*95?92;!-;'6<$!/!"@G0;H7"FG?EE)"G,@F+):CGHH-86.D7HE/"#):-C$9"&).)'!/5-@B&7B-:66/<#G:!-;562CH:!H#HHF&*)4*=>.F1>(2:>8(56<*=0!;%0BB8A4?5$.4$9H)+F=53.+/$B<8?2>6*
@r4481
CGCNTNTNGCAAAAGTTAAAGACCTGACGCCNGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGAT
+
*%%")$&#+)(*%$')*#'"++**$+$+*#%(*""#'!$(")+$((&&!'!&&&%%)%%*!'%'!+)%)($%)#***
@r4482
ANGGCTTCAGCTGTCGCGCTTGTGGATGCGGACACAACGAGAAAGGGGNTAGTGCAGCTTAGCAGTGCAAGCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCNGTTAAGGTGGTAATGGATGAAACGAACANAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCANCCGCGCTCAGGGGAACAAANAATACCCAGATTGCGAACACCGCNTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCNTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGNTGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCNCGTATCCATCGGGTGTGCTTCCTGATANGCGAGGCTGGACAATCAAGGGGAACCCCGCCAGNGGTCGNGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCGCAGTGCCAGTGCATCGGGTACGGNTTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTT
+
#"'*'+%+)+)!+*$#&))'("""!&#)($"$#++%#$%%(+(+)&%')#(&+*+&&!&"*#+%&#$"!+*()&"'%)&&$)(""*+!'(*$)+&!)"+!)&"#')+)!(*+&+*'!((!*&$%))"')$&+'&$#('"(("+))%!#!&)#+#+%*)+%$'#)"!)%#!&"(+*)$%'(!$**$%'+*$*&#"*"'&)!#!%#+')++$+"&*+!'$$+&(&(#''!%)'!+%(*+(%#"'($*)'"#%!(!!'"$*)(+++(#($)!&#$))#%%*#)%#*&&$*%#(%$#+"#))*$"##*"$$"'+%'$%!+&("+*#')(#*%++)&+(&!$)($!'+)+%*"%'$'(""$!++!$(')+(**'))+#&(%!*+&"%&((""%"$*$!"*$###(!%!&((!#+$$$!!'*#'*(*)*##&+%($#!)')&!+!#"++!%")!""++*+!%$()'*")#)*!%!$%&%)#+%)*$%)(+&'!!""+$'$##$('%#&)(')"$"(&$+'#"!!$(&'%*'($)'*(!"'!&+!""""+$*$+#!+""%&#$)$'#&()''"##**!("(+&*('#!+&&!!+(!*%+""%*+!%$+&!"&##(''*+#&"***'**%"%)+*$$$"&!&#+'**&#!(("%#)**$"%+(*++)%'%!)#)"#$"#(()&##)"*"%)('()#&*''''&"*%(%*+&(($!%!(!&'#*'"%##$'##*#$"'#%"(+(%%#&'&$')')+&!()#*%)%*#"$"")"&&)&$+%"+%+!#&%&%#""%!("'*#!!%%*('+('*)$!%!%$#$(&"""(#*%)"%#'!)&&'('!*#&&'$*("%'"#*($+
@r4483
GATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAANTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCNGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGG
+
*.49?.0*.*<2FA(,8'?A&>.1CA2>*A6.H7CH2.+E!")-/20!/7".!6B6""H:!AE$?-E>GF.%!1+%4*!8;5ABE%H3=<&,;.0?.5E>0E+-@";?$G.%=<$;/DBG>6'0:!F?*2<1$/#9BG"%0.E,.=;51'>B?6#BA"D$=&##0A(494)6G8H0DG54(*?'4%"E:?84%7'66:>@@A'/8;98;
@r4484
AGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCNTACGCCATGGCCGGAGTGGCTCACAGTCGTTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGNCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGNTTATAAATTCTGATTAGCCAGGTNACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCCCCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCA
+
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
@r4485
GTCCATATCGAGCAGAATNCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTNACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACGGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGNGCCTCCTGGGCGGTCAGGCTGTCGCCGGACACCGCATCCGTNAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGACAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGA
+
=+C?>.313+&@#<?>,(**F''7/A@0:F6:8CA.:<'C(?1?9F:!,D*.B28#9;5867>!@2,81-.G'0G.G6..;(=:+H,$74975D/4)=(46:*)<=C41))-2/2*,2)C%?G#$?D;CD$1>CB(HE)==,!)E5@";?F:!+65CG*'D'!?<@<E?)>09<#>6D*1-88%0:=CDD!BBF1<5B7'7,-(=.FDDF/)7G=*/;:F@>F@)FB9@5*E*BH53&:F;;!C0C3!&!8F$36*-B(C.*?;"8$%1.'<F>&A2&B?>G+.+5,*3%:$.2#CH<38@/B9H#4@D'&641A$'(;50%B=1"$.D<"'+)E1@?!?.$2E*E0(G@G@&8+*G.&40960C)F0GD3>,:/B#"C477A,D,2;2#?"F@3E*.1+-8.B>3DDC?-?5%5#;H0;F$F#@A&3(F'AG:"76-.>3!?/1C)%:?&@?%A9;#&:,GGGBG</614E842ABF<137-7%!6%;:@!E>&
@r4486
GGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTGTCCAGAATTTGTCACTTCAAGTAAAANCACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCTGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACCTTCNACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATNAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACANTTGCATGTCCAGAGCTCANTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTT
+
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
@r4487
AAGTGGGATATCNGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCNGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGACCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCNTTCGCTAATCAGTGGTGGTGCTCTCCAGAGTNTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCNGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAACGAGACCGACTTACCATGTATCTCGTGCGGAA
+
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
@r4488
CNGTNNACCACGTTTTCAGCATGAGAANTTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCGGGTTCTGATGGCGTCT
+
*'%*%!+++)##)+*+)))")$*'$!$+%#*!)$!*%"*)'#$!*$)!""&)(!*(#'!')("'#!$'#&$$*%'!&!+&+"$!*(!&#)+*&)"'*'*!)&(!##%!(+$$'!")+**!%($"%+%+*)&$)$)$+!!'#&+$#)+"(&&$!!#$"#&'+#&'%%*#
@r4489
TATTNNTGTCCATNTCTGCGGCATCCAGCCAGGATACCCGTCCNCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATCGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCNGCAGCAGTCATCCTCGGCA
+
(%'!#!+*+%*%*%%!)%*#%%'&'#+)&!!$%'"'%#'$%&*#+$#'"$#!)$&!$*%(#(&(+&!&%+*'+)%$$"*$)$&+"$)"+!)"(*#"#!$!)!""&"%*&$&$"+())"&$%&'%$"$&'*'#)*&)(&((!++*!***(***!*"+&"#$*+#$#"++)'"#(&*&!)*$#+&'++"+'&*"%%')*$#")*(")&*+'%'!++('*!+""(%)+!('!&*('"*"(&##)'(&%&!#%#"#('%"!+(&++%%$!%'*!(("'&"+$%)**#"+(+*(+#+()%'#&"$#&!*!)!&+$$"%
@r4490
GAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGATGATGAA
+
++%+#&%&$+!$!)#+#"*+('$&)*""(#(#)*%(+)$%&"%'%"'&!%"$&)#$+*)&(!)++!##"%)!
@r4491
CCCCGACCCNCTGGCATTTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGNAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACGGTACGGGTACCTGACGGCCAGCCACACTGCTTTNACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACNGTTTATCGTACAGTTNTCAGCTATCGTCA
+
-%%6@G*?+-@/9/'!$D:>)!GB1$48G4=?C.A:#(#F)F.3B!F<(GFE:7'469F))G;??D7$8:>$);1FA$!6+0=EG3FE%B/8(!0-24)02-'$&H;7H+++EG67H(F-0<D*'8:>,EE>'1C);E:>(?,D+-/*/F2G:(73?@!..4->"!7?#77!,'>A&,36*8(-$G8@,@,8!3;7;1*&"?C+758.#73@(8"C$H9@>6.E8%:9A4@0=#;0,EFB$'.$CC8=B++F3%29$6!*8:-H@%'2?5</"F8B!B.<(=?D4>G(?'B)F:D2;0E+CCA#EF&*-2'2)'<E91?AA"A-0)#EB+F:!C1@=F5%4$HA;
@r4492
TACCTGCGANATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCTAAGCTGGTCTTCAGCCGCCCAGGTCTNTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTNCAGGCGCTGTTNCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAANTTATCCGCCTGNTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGNAGCCNGCTGGCGTTTGTACTCCAGCGTNTCATCTTTATGCGCCTGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCNAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTNGCTGATTTTCTCATTTGCTCCGGCATNCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACTCTGCACTGTTTCGGCTTTTTCNGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTNTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTNCTTCCTG
+
$'+)#)%$!"%&)%+&&&#'*&*!%($)%+&*%&(!%&%(%!+&)#%''"&"("%$'+%$&*"#$$#"!("'"$!+'#+"#$"$(%#%('('%!$!$(+$##+*#+*"+'!#"'#+!'(#!(')#)"%&!&"+&$()%%*)!$&%+*"$$&$*)(("%"+'!!*(&&#%$"#%'%)$'((!'!&&%*$*+&#$*&$'+)'%+$&&'()%#()"*%!"*&!#&##()!'#!!"$#')$('#$+"&#$(((*"%$))"+#"*))'%)"$'#&%%'*$("+!$%&!!*")%+*))*''%(+"*%)%)$')(!$##()!)$$#)($"*$!'(+!*##)*#$+)(#*##!&)&*!(*$)"%&+*")!!%'*(!'##)&'')'*(%!$*#*$"'"!#!)'!*&#+!&%#&)%#!&%)!+"'%##*")+*#*%*$$!&*##$"*!)$#$+#)%''*$)!')&*(#)+#%%"!$$#+$"%$*!$##!))(+'")%#)*(&("&!")+'(!'(&$*'&'!(+#%"#"(*)+'$+'%*""+$&#))'$##!+)%(($'$$!"$""#)!#''"!&&%!*'#&$#)+*!!&'&((!(!$!#$($"&*)'&"$*!!(&))''$&"$((#*'))!$*&!+$**$*"$"&($+#$&")#%&+&%$*!(*+&#$'$"&('%*+((%!)"$!('"'%!&))(&+'%#')'+!*%#*
@r4493
CATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTAC
+
1<,+189=1-5!"*:-D:;8/(7G<$B$/,)"F1;@6%153#C;1:"(++A'":B3F".&)3!5$(@+%CBGGD4(531)5,%3A;A91
@r4494
CTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATNGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATTCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCC
+
.6F>'4"'<+*53!0?7%'851%H+;*#$'3<D28$@50DADD0)39$&2HA-@>8;2?8C.E/=0F=0/,H"GDBHAA+39"-#$9-<*/$3FC'4#>=%!E%6EH,H$G54-%G15.%C9@!+1&7?3&>!E0&9G@'</5#,E4E/%2F/>9;<18(62HD62+'%3:(H(*>78"E@;3H1HA#=&!F;/HG+E(0$=&2#:2F.!A@B&/@(=E?""?<E'C"B%13!GG6,%!7.97A2
@r4495
TTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACNGGTATCGTTTGGAGGCAGGGAAGCACTNGAGTGAAGTGATTACTCAAAGAAACNCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTAAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTANCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTNAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGANGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCATCTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGNACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAG
+
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
@r4496
TAGATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTCTATNTGGGGGAGAGGGAAGTCATGAAAAAACTANCCTTTNAAATTCGATCTCCAGCACAACAGCAAAACG
+
$&$&+(#')&)"!%)$"(%(*'#*%++'%*((&')$"!+$"!'"+(+#'*&$(&)$**'*$'+%&$)(%#!'$!+"&%*#$%&$&)(&&!!"(*#!'&!!&+#!*'&+&*&#)#()$!)%)&#("$$%#$&&)'++)"'!"$
@r4497
TNTNCAACTTNNNNCNGNCNNGCGNTNCGNTNGNNNNNTTGNNNCCNAA
+
$##!!##$#$#!!#""#$$$""!!#$#$"#$$$!#""!$#$#$###!##
@r4498
ATATGAGGAGGTCTGTTTTTACAAAATCCGGTAGTAACTT
+
/!*92:-11A49G:.#9/DC=A!FD:52+$C*H6+(&).+
@r4499
ATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCNGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTT
+
4%BGA$;+;E-1(%?H2F9$:#A.C.:!C?90<F<*'1/!"2D&<$<6.7<$-6%EG/9HB.%%HA6<7>'G,.4@2@-"1CB1%.4
@r4500
CATCAAAGAAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGNTACCGTTTAGCTGAAACNATATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTNGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTNTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGNTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGNTACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTNTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTNCAAGACGCCTTGAAACAGTTCGTCGATGGGTTNGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTCACCTTTATATAAGAAACAATGGATATTACTGCTA
+
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
@r4501
NGNCGNTGCCNNTTCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAG
+
#)%)%!**&&"!(%%(*+'$"!!%!()%$'+$$+!###$+$"*%'"&#)(%"(!#&'(**&'
@r4502
TTAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCNGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGNCACAATCTCAC
+
/EC++0'!1=%/<2+9*6.@@+B7">,1-:A87+G,@)&/12$/5?CBEE1$:?2E//7419;?ED.+*;7D;D"+;>=*D21G&(G98>D7<)/B9*.$D&;.H3!*C"'6E1)'%&08$
@r4503
GCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCNCCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTNACGCTGTACGTTTTCAGGTTGGCATTCAGCCC
+
'?5H7$9%;9G?GE,A#$9?;C!"8)$%79(<F(6!E36DF?3A%!*!A%/2E@649DG;>(0?93H'D,4HC!BF2,@!<8>?<$*6<C'*?9GA*:C$.4/D+17&A.5/(+%12!5$@>'!92:,A$=(:&*)+7D49"*0@0$19+B0/;6'<9D-(7@5<'-@*F0:DDFBH-0#H;&:
@r4504
TCCGGCCTTTTCCCTGACNCCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGA
+
"7D>/(=5*";3C9/*D7?*1#,%E(?*B;<F/>%./'95&F67#A@<G/8;(/FC3"%B(8!(;,.A
@r4505
TGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGACCCAATGGCTGCCCCCCATGCTGCAAGGGT
+
<03@32+.GH$1;?.*+D5/3!;'?6-:H?05/F61FB2::C3)+A&8#HA2(6?70GA5FA!H+.8-H54;2>#1+B+D3<C2B"#!=47*D+=8;-=A6.4E$2#:)(-GD!+
@r4506
GTGCTCTTCCAGNAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTACAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCTCCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCNGAAGGTCTTCATCGTCCACCNCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTNGTGCCGTCGTTGTTANTCACCACATAGTTATTCTGNTCAAACGACCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGNTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTNCCCGTTAATCCTCCGGTNGCAAAATG
+
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
@r4507
TGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCC
+
89)<:@486<31,>!H(DA*@GF>':DH)?<-663C"#!031H@0H+&B+:22F.7H$6*<,(4@:2G9-3')!>+51":/F3;!&C#@(+>H6-(42>HC*-#>,/4-C;:>%F/61C/"E=-5&B&F;32@1)'.?)+$1H"$$2F.,()G02,92699@#,C#64,)=8??86#)*"9C+0D
@r4508
GGTGCGATCACCCTGCCGATGGTGNGNGCCACCTGGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTNACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGT
+
8A$*HD#9;/029D(C=8!567E>C!*BE1.A>;%!!9+.+:8989+4=!A281?<=7+:&84'+$G4:&H@%<#ED!('C?/4%@;.D$-0$G5>+.BA)&?H+H(E!;%D%15,7#=*6.&4&FD9&.2!4*4E-.3/)%H)/49)9<HD4G.795D-9B&(*C-=!+B47A33@,H*%*@'>D%#A@%$C=@78<7D7(9?"5GC9".B&#5DG@C=(C5):4C>B68%28'2#;B=!?
@r4509
TTACGCCGATCCGGAGCAGGAGGTGATNAGCCGGTGGCGNATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTNCCTTTCCATTAACAGACTTTCGTANTAAATCCCA
+
70C-+0@"@(!1F9,$5/-1B!G-!A2HF45#="7'F,9-&1A0@(B3AF//%,F8,("2*??=/=3;*'(-4(="10$;-H753=!7/)<H@":2:!$).EH'5G0(#5:G(,E&1::A,B2")E*#)($'%)"+0@$?5>&1:/.-&D6>)#"+:-9HBG7-.,1"+149>"@?))9#;B/(E8)'-@9>5/27'>(G%D8*.163C@&GD*%<*%*6D-:G:F**:12>A,'C&&/-*7@GGD@&GG.>44427B<7$$<CDG()4&')>A7,3!>!5<0>/D/,,.B#*1+3.BD@;/><E%%5A++'!;,")""(63HC%4)+#,<B(9.31
@r4510
TGCGTGTTTCTTGNGAATTTAACATTTACAACCTTTTTAAGTCCTTTTGTTAACACGGTNTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCT
+
FH)38+&>@=#$5.'7!EF71""-)$3B=F2)114*9/G'6@';)4=C/8%.DA+*$H>,%9,0A88D=<#*G9&%33DH673?-*.1*G$?20-4>0.G&71H8D1D90,&38&9=75)1G07.=AH'0%A,!'D?D3:0!4A7@53':0ECB25<BA++#:=:E8?/9*/%%#.7!"21;0.AEA*214B
@r4511
GAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGNACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACNGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCANGCAAAAAAT
+
9%A!G=0!.>(=/,+@E.;5C%$+B2*C38C<(E;EA631?(CAD=C,50%=.3;B!/F@?>0E86303@*.+'&$<B59;.&,#,:9HF5F)<-@E;E.GD$!'518;&>,?8#H*GE><D"B1H:F>F:%#.2F14&/D90*,3196'!C-,A07:-/@!?6;D(/20$.7B1+"&&(=6DF7=H).,:57=F&73BE-%'G="'29@0D$&&.@@65@!<0C##/%>2C:%#41!A7FE8!A+A>!%C)FD@(518@AAD3H'6"D)*6.(D/D':<89E:3)FA>962*7.E";@("7&@/*"E
@r4512
NGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATAGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCNGGGTCAGGNTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTNTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCNCCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGANAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAANCATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAANTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTC
+
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
@r4513
TCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTCATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGANGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGNGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCATCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCA
+
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
@r4514
TTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATANAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTTGCGGCNATCCAGTACAGCGCCGTNCCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCNGCTTTTCCGAGAACCAGAACTGAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGG
+
<-H1&5$562'!3/-@-698<E*@C&&!),''>3.3=#)5%7H";%@?C>>&@6=5-1+,0B@EE:=@9:!"2=1-",44D.;0&;8--!@H$7E2'*<$3*%3.756-4HE@;7E6';@$E7+>&4'1?:35=8G::B77<&AHC0686&:=*/7;1>$*-:&B7,E6->G(D:G''FG><*2:A1#:7.0E&DCF?)='+9?8A4$)E!.9GDB(-E<0A5="?9&9-8B,*5<$;/E<E@E*-8-<+,=+!5$7%/%BA?*G/7/+!A?-59:/7.9904F&E&6)1F%+CCG+D=3:,;5B)A88>.35"F6205,4C=&>+,(0-57FAD%EBF:D=&$;$63&"F
@r4515
TTACCNTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGTGGTAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAANACGCAGTCTGTAACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGNCCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTTGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCGCTTTANGGGTCCTTTCCGGTGATCCGACAGG
+
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
@r4516
GCTTTTAAGACTGAACGCATGAAATATGGTTNTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCNTGAAATACATTTTTGATTATTATTTGAATCAATTCCAANTACCTGAAGTCTTTCATCTATAATTGGCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGG
+
@4;,.&!'*"&+$A8B6%,?&'%9HAE&7H-6;F;!"+8(%$0!9(!:F<.0:A("D3>DH-E>F,*;8'$#(*F2*<#>-";#+4!5'8((55@6':"')"@@(99EAC>"31?,",9)<*HGE93$?(@BG/ED<6A!(++D5-B7>'>7!0+6&/%,@:#F5;9%6+>#+0*?(AGD@7/3$0A;;G:C5D;A54@9BDFE3@6C!+B/#>>*"81<)$8293"7@AG*A11;,?/:/"H,C0)A
@r4517
TTAATTCAGCACAACGGNAAGAGCACTGGCTAACCAGGCTCGNCGACTCTTCACGAT
+
@;.?),"3$/.;;:7@#(?)/5=##16D&;C"F9)'$/@1'%@'E@>62-:$#8-13
@r4518
NAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCNGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATNATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATNGTGTCTCCGGTGTGAAAGANCACCAACAGGGGTGTTACCACTACCGCAGGA
+
!1(:4&C,)%DCA.;-5-C+9(1!=.E)4$2%D7-D>%=7&7<-!*B'%09<'>;$@81&?9$".F.B@(<<*G9&/,;1/6=)$5$37*)EEBD#D)*/89"7+3D:H7@2"+"-50/&(G57.,F#D*.=>"A&A<7G+H3!8),4?2":G,C=%5)#(732!.41D/#E8E#-!:H85C/7#!41<G;14>(<60C5)62*2;$><1-A><8C6:+(7A+GB,"3($F:E</)-9&'=3CF+)3%>)&!7>"">5H8C'$,@>=6""2(G6D2"+)/B=B;+3+45?@
@r4519
NACNGTNNNTNNANAACTGGCGTAATCATGGCCCTTCGGGGNCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGAGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGANCTTGATGACACNGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGNGATTCTGGATACGNCTGAACTGGTCACGGTCGTGGCNCTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGNCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATACTCCATTGCCCGCGCCGATGTAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGNAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTNAAAATATCAGCTAT
+
!##"'("!!#"'+!)'#&$#(!!!""*$'*##)!%&!**!**%#$(")+'+&*")(+("%'%&)$(*)$$$&""$$(#$#'"$*)'*()($+$"!#)""'*)#!+!$!*$$+$((**)&#$#"!)&!$+!"%!#'*%'*!()"#)'%*$(')'$)(&&!&)*$%%(+!$"!+(!$&!$$%%+$+#)(%"+))*%%)'&(+$!!+'*&!#((*#))%#)$*('+!%*("$&#+%('$$(&%$*%'!(!&%&!'*!*$$$+!#*$$+('!)(+%!+)#+*(%+*+"!'*+"*($'')#'%#!*(!$+!%(*(''+#($'(&*&*%$'!""#+$+)')!$%*$(&+%$!'%#&%'("'%+$##()&)+('#%*''*"*&%!!"!+'!%$$$())")&$+'+'&*(%"*+'&'$)"!''($#(%%*"!)'!)$&!'+')&$))!'#$*$'!$)'+)''$&(+!%&''&)%##"#!)("%$((#$")'"+#(+#$(!*('*%&)!%(%!&&+*'&+%+))#*"$*&##'("')"%#!*%'+!+**#+#+!%"*#!+#&+(%&*$#*%!&!$&('($*%%&#'&")&)%)($)$)!$#**'*+"**#''!!#)*+&$(%'+'!()"+"&"))&&
@r4520
ACAGAGATATTTTATGCGCGCACGNAAAGCATCAGGTCTTTACTTCGAAGGGGATCCGCCTACCTTTCANGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCAT
+
H?'!%<82";H3=:'@16.+,A2*E=6>=?E'4;0%91924?,,</F1%<D''=<A4:/-,0"<;*&F@>,$/&F-),/>,28D**H!6%)#:%F2HE;-6>$9/;"7DG+4+*9,>6-/8;$A"*(69A?(;7-H&4"7!*$G..$$>0)D0E$,EA9A8-9C
@r4521
TCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCGGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACNCCGACGGA
+
$91$E(&6G&5C.6.="@FDCAB&:B8H?H57/9@**!,9H&DBGB/3*C5513+%*9A<+:G"6?3.C-?<':'G*!=0.5!,@#)5'=;CH/G&7@+:/,:'H65$9&++$-)A$GCG:#H0?#,!8(>&@?'/!%=>51A56''H+5(;.%2.D.A&.5%(*"%/-5-;!B(
@r4522
ANTNNAGGCTTTGGNTTTAGCCANNTGGGNAAGTNANTTCTNNNACNAANTCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGGATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGATTGCCATATTTCTTTACCATATCGATAANTGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCANGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCNCGCTCTGTACCGAATGCCTGTATAAGCTCGAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGNCCTATTACCACAAAGCGAATCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCNGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTNAGTTTTTTCATGACTTCCCTCTCCCCCAAATNAAAAGGCCTGCNATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTATAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCCCATCTTTCCTTCCCGTTCTTCCCTGG
+
'")('*"$)%%&#"!'*&#*%"&%!%!*($&"#*#$&($&&#(!)*%**!"+($+("*"$+!!#("%%)$+*&*$'&+!(!($'%#$(!+%*"**$%$"*++$!"!+&$('&))%()*'"#")+"")%$)&$''"#*#*(%))%&$%)%')"****%*%#"+)))'"(##+%*#%*%)(%)"(!'+%%*+!'&#+%#+&##*+"+'+#""(''$+**!""&$#*&%"$('$!'"%*+'%$"%$*""+"$%%'("(+!(#&%)#%(%(!)%$&+'%$##%"$))%!&&!)$+%+#$#+&+%%)!&++*$$%(+#")')&$+"(*&%%$%#)$#*)")#)!("%%##)!##$!'!%(&%!$#%$'$"'$#+%)&&"'+'""''$$"#+'(!*"#!)"(&&*"!#)*#("%"$&**"+)!*"+(#('&&')#&!')$$$$*%&+%'&(%'*%$!)"!'%)%$&()&*!(+%%!%)$'*%'%((")!+)+''!("&$*$$)(####%(!#$"&*"*))$&('#$'!%#'&#*&*"+!)!")%%*(#(#""!*$&)$+!%+&&$)(%&()$$(+#'''&*$!*''$%)(!#+)#!%$'*!$%!%""!('*!%!+))%!***%'%*)!+!++*($)''!+$*#"))**(&+"'$!$$$&$"*+*$''(#(#'&")*(++)(%(#"(+'#%("%!#'&+"%(&#)#)+&)!'"$+)&!)+*(#(+%(%&(#&%$)""+#&)$$!"")$'!!(&'"#''*%$!!!+')$+*)$$'$$)%"'!&&*'('('+"!#!%"&&+**!+)%(#%#!#&&*&')#"*)$%)$')(("#"'(*(!('*('($''&($'#+""%%#'%!#$"%#!%")!""$#$()!")+)$$"+&##"+$*()&(#(!$%)%(#)&!&%'()!#+%&%'&(##&$**(+*')&)()()$$'#($)%&%'#"'$%!*%*'('$'$*##"#($#(#&!)$*)($+*)%#')%)""+%(""""+$#%)*(%*+!!%&)#*$*+$(!(+(!$+)%"!$""'(&'*###((*#(**#')'()'%##$*#+'(!#*%%+!'#'
@r4523
CGAAGGGACGATTGAAGATCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGNTGTCACGGTGGTGTTCCGGACTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGANTCCTCCGGNTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGTCACGCCGA
+
A/#H',0E%B-%@0&8)5>!</E2A(?D/6"3-!+4,>04G-@("5*D)/A.;-<B-1*.@A9G%79;9G6BG%>D0#>%;;GC4*FA.2,C19#+-4D#)&)D>!E+!7>?==DF=(*C,5H+3&9A"3>FF88D6&42@?:6E:,?):G$5?!2%0C3/4;$&/$1A%'69/0,$D2B;/@$>G%F"00#:<.-G$(BF,&,08
@r4524
TTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCA
+
$9!;4$9?+<G,6?E!/,:9$)+=A=)-6-#175CH/&G@?E4>(:G<@!6&5@EAACB?":=B7="<-"A72A%8"!E6F:*'0F-=D!>;??C!;+.))8(H'9-<A@,H4(9,GFE%,6+(F$D2>8B,040B8F*(;;,2#8EDD$(")*<9
@r4525
GAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTTCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCGGGAAGACACACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTG
+
+++#*&"%#'*$'&+)&(%$#%%#$%%((((*%#"*)*&)!&#"'!&!%'"((*(+(%)!"#$)$++**)'()!&**'(%!#!%!&**('!$'$))()!+&&')&###&(%%#&'!&"&%%%%'$&+&$!)*#))&())&"!(*"&"#+'!%!(##%##$*!($!*#(!"+"*)!!%*+&()*'!&(#$!"'%%+(*"$'((&&!#*#!$("%"!%'&('&)(&$#+$!%+)(!#%*!"&&!%
@r4526
ANCCNGGANNNAATCGCNTNNNGATNGNCCTNNNTCNNAGGCTGAATTCNNNCGAGAANGCNNNAAGTNNTTANNANCNATNNGTNNNGNNANNANTTANAGACGCNNTNNANNCANNNNGGGNNNTTCANTAACACNNGNNAANTNNGTCGTCNNAANNTNNCNNNGATCGCNNTTTCANTNTNGNCGNGCATGNNNGGNCNNGANGGAANNTTANNNTCTNCATTTNNNCANNTCCNNTTNANNTCCNCNCNGNNGAGTNNNTCTCNNNAANCAAAANTAANTTNTGCCTTNCTTNNGANTCNTGNNNNNGTNAGNTTNTCNNNNNGNCGNANC
+
!!!$#$$"!"!"!$$#"!#$!!#$"$$!$"##"!$$!!$$!#$"$#"$$!"!$!"$#$$!"!#!####!#"!$$!!$"#""!"!!!"$#!"$#"""$#!#!$"!$!!$!"!!!$"$!$#"###$"!$$#""!!"""##!$!!$#$!"$"$"#$!"!!#"!#!#"$!$$$$"""!!$$#$##$$#"!##!!"$$"$$!!!"#!!"!!$##$!!$!$"!##!!!!$$!"#!$!##"""##!$###$!#!!!$$$!!#$!#!"$!""#$#!"!"$#!#$###!$$#!!#!##$!$"!##$#"$$##!!##"!#$#!"$#$$!$#$#!$#!!"$$#$$!#
@r4527
ATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCNTATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACANCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAGGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAG
+
FD:C&-6>>6<;++G4B';B.@(+4*,)*3$89$4A(2%$%B47!*?.%#'*70(*6.#(?=1!6+A5?.8$%#B3+D?):.A,D8H30#=7"<='*,F'F6+&"(G4#)<C1+0'&*6:6EC><.H=GFB28E*.FH7E$/9+8?22?DG7=?/H0)99B$2!<>8-<-B<3:-,$<7G/(+8+'C7?27.@A2(@C0/CGEGG+H@!3=*-92G>20*HG#G=G?B0;,,#:,,#4,:6-!)B)<!C%?C10:#%?.9118>A7?F+A7";=>>$"8G:,G$@AGE$@C'/&'#D&(@/0+#/8?,6/D?G'6H79D'FD;#A!D>/!;."/>*><&.:=25,5A%F&+=??7172:3D6A1(=,02:*(86CE>5'1?"G1!%D'G,$6!91A?D,:%-D(4A$+0,%1)G@AC:3
@r4528
ANGAGGAAGAAGATGAGGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCG
+
*&)+!'%'&!($+#&)'(#+++*%'))$"!&(""&""'()"%"#$&"&!#'!"$%$!(%
@r4529
TTATAACTTTTACGAAAGAGNTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCNTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCAC
+
E="%6-+?!#+(;+),,6-<'(,HC)*9%8*?*-B2<78:'>.9<E!4?G?95&3+=@H@00;350(5>AB.%.G'A)#%'#9#/""@".?0B"@%?9<0C>:.1'/9<*@5&:(11+$DB"B5G&=;(5+"%->5CE0#!75E-E+<<7?#*HG@1FG4;,507%H&CG$H'/*2C@%5/3351B*"9&38&B=?-5717:0=/1*72D
@r4530
TAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGANACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAA
+
>;H1<+-.B-FE2A>E"(/8<<=?=B>=2!=+-44<"3<&&D-.7:%)@$.21-92>F2CF.$-+:,6&HG@05GC//:H'.5%4HD#C>0B)6(5B))%1'54:DE0A79<C9/C;*.!56=:;@14H<@(?.?-#HF?G;!-/4(2>*.A+!!'.?)$;%!5-@9/>(>()"+AG0+>-5-/G:"@2&+6B)*F&E8F$.7'>C7(;)!027*0!@)>F26'),;/$F.1+>.8G/$=&;-0%EA:B?9'H%1!A+=1B"))44(81=D&>FA>0-?@2-HB4(;B*()"@E@,-+-3<37@4.+(
@r4531
NNGGNGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGTTATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCC
+
%!*$''*'+$##*+()!*')#(""('#(&&"%)!*!)#!%+&&#$))%*"##*!&'#"$*(*!"%*#()%$)'''##"%+)(&)()$"&&"'#)#"+$+&&%(*#+*('"&*$')*&*((#'!'&*+*%+(%%%!"(*"(##$!&!''#($$$!+#)!)*&"$(!$+!$'"'&+'%%&(#!+"!#%*#(!+()$*)&+)&++&!)!!'"%*%&")'!%'*%+*%!"#+!''*#$"$(('(*+%++!"*#)$#)(+()#%*((+(!#*'#(#)##%*+)!%%)#'#)"!&%(#"("*$$&!"!)*%'#!&$'!)('&'!()#&(+!%'*$$)
@r4532
GTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCA
+
B%*+,?A5-002)2A7+#"%G"''FA'H$FDC71'AF&F()6"*+4&;9&4@217B@23:A@7G+A>74F?5-$"<</AB$#*-775G/5.==2
@r4533
CTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACATGCGATCCGCGACAGCACGAAAGGNCAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGNCATTCTTCAGTTCCNGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTTAATAGTTCCTGGCTGGNGATCTGCCT
+
G?9H)>A5-7/):0"-450F,,>6HCHG,-=1#=/*'HCA2BH"8E782,A%H6%*"D9:*.&H3!<&.<E>!0:A($7@*1":F57C%&,6.%5$'(D=A203)G527H5%B2#4:7B*HF!7E99!/E":$H1B#7>>:<9;/")!."B=6>6.=:(AD<@))9!4;8(1.<?B":35:%:E#13<H*CFA*3&(?,8B$*>-@1%<F3'E">$2%).D+#=F7D,):;@G=@C<#?.13)+81>$5ED)=8?*<C0B/B(7B9*@&B$1:(79*$#HG<?""2**:&9C(!C@D#;"+'*4.E1,>%+"7!H+,9:732267?GC7*#B(%%;FE5:#&+4$2?6=64,?!;C5.3@=6:"/::!"0*5*!-D-6
@r4534
NAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGA
+
#<"H,$3;B.4917*!,!@6:6-%A)-*?435!>5,@/?=1$&E1&#
@r4535
ACGTTTCTANTCGGAAGCAGAACGCGCCGANTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATCGTCTATGCCNTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGACACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGNTCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAANTATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGNCATAAATACCACTGGCGGTCATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTAAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAACCAGAAGNCTTTGGGGTGTGT
+
#+$#+#+*(!'$+(#%+"'*#(&''!&'!&'#'''&#*$%!$(#+*)$('"'#*!(!+!*"$'""%#$%)$!!'&+%+!(+(*$$)%$(*"$#%)"&"(+)%'''#$"&**&+#)"*+!)&'+('&#+*%!"%(#*!(*"*#""+%%"!)+#(#)'")))'"+!#&'!'(*#)&*)$)+"*%%'''(%)&&#!*##&$&**(""+&)*+%*$)"+()('%"$!&$+(&&")$!"(+'()))&&)$'&(#$#&')+$!$#*$'!)"#!+')$)#+!+#!"$'$++*)'!%*"*&)"($+#")$(&&&'"*'()+($"+$"'(&#&!!&*!$&%%*(''(#$*#)+%+&"$*!)+"+'"%##)"'+%$'+(*#!*!($""+#+!"%%*((**%!#("'+'&&%)++))$"+%+'#))*#'%)'+*!(%&*$%#)&%%)&+&*'""%(+&+(%'#"!+#+!))#'+*!)$($&%*!*+$)&"#*%+&)"$$))'!)*(%"%##$%#!#!+)(#)%"+'$!'"*'$#)+"*##*%(%"()+(++'+(!&&&#+$'!'')"&*#)"&&*#*)'%(!!%%)&*#+$#!'*+"'&"
@r4536
AGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACC
+
.4H&)(4:-?&H@E%!=*D;$06#!.8/#=;AC=2"73AF"%"(&4:4#)E#6,69.G++DB@26H$<E!"G4#'2=>G(!7&'B>(<$(-.<&E1$<*0D>4/G0;.41#8;B5(<3E9"G:1+
@r4537
AACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGANGTTAGTCTCCGACNGCAGGCTACAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGNTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGNAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGATCTTCGTTGACATGAGGTTGCCGCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACNTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTNTCCGGTGATCCGACATGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGNCCGTAATCAAGCTGCGGGTTGTCCTTTCGCNCCGCAGGCGTCNTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCCGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCGATGCGCTGC
+
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
@r4538
ATCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGGAGAGCAGAAGGTGGCNGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACNGGGGGATGATGCGTGGCTCAA
+
*&&('+""%$+(&*#$*)'+"&)$+!$!+''+&#*('#"&%'++'+"'++$$%%+')#$'()'!#*+%%"$$&)&"%#()"*""(!""+*##!+&!$"$$#*!+))#(!!&#)$$*+$(*"%%%"&)()%+*')
@r4539
TCATATAAAAAGTATTCGTTCACTTCCGATAAGNGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCTTCTGAAAAAATCTT
+
=7.D?8:$21-9G#"H/"-$@!)':!$$E818D9<#$<=G=&@"A)<<F+6-,?FC/&/(B"/(7E6%'13GE+F4H2"2AA2/7
@r4540
TCAATGAGTTAGAGTCNGAGCTAAAAGATNGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCTCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTNCATAACAATCCTCGCACTCNCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGGTTTGTTTT
+
8'$E'GDD=0!@>:D;0H?B.@,:$(%HE'*759=/C>1G"0/$H05A5*0/">#;F0GC*$+6#>,'@02;)$8E3/H4:3E&/8$*269>A4'-?!#)G'=7<->=&+>9!*$5G=F?94@;2G71(BG1-+G42%:G<;5A1'A,"0*,EF'#/>HDA*3=7;D5/*4A$2&C3"'-2A5<A&4=C4"023/4-"30"#B%C,7*!G2=%!CH*D*CD>C&GG;>5H<C,D9,:?5HC-;!35%*#%3&H>?!#'12*):-)#3@*57<A:,"$(<5*",/3G*/BAB@D)D&#D"&+FCAF-/;"CH5$:=1=*H&7H(@4D.?9-AA#H#'G(=&B"1+)BD@;,
@r4541
ATGTTACTGAATCCCCGATCATCTATCGCGCCGCAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGTGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAAT
+
7-?A?)#4<?A6?&)?26EE=*BF6,>06<D1(BF4DH:/(<.H8?#,2?GB%"219!,,E60?42>G0@B<G-=,;96+G3?%81C,7A8G@?+<"+0#A!D<+',G"'G+2,=@*,/?'""/+%38C1@"=E&CA@(G+1,H?@(,-;*69.)=E@F)51@$E*/8$G;--@@8/@%;1$"%BA*,E9>'F#:*H61FBFB;&5<EF
@r4542
AGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGNTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCNGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTC
+
22#6E6'#)0$=,=H3&GCA9<>'9@C$H21$6;"?:3<F4G3>0B,'1.)%#@'+'/37>-'/$-$#(0('"+2%3C5)%1%;BG+3B7<+241=D&/<.5"9C$*"H8()1).$EEA&2%<5A)*:&$,=%F@4?%&C";>8;H(?)4H873A<2#/D14<-B*/G5!6@A"E@@F>=/9A64EH0>%112E3D=,<*;?<GDB6;5?693C.'*C4$;==4"G+4@+8!:A94B0>FH3"*+&)AA"7
@r4543
GAGGCGCTGAGAGATGGCCTTCTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGC
+
A'H2&H6!1;@-(HD3&4A59%586?=%5G86(4A!-0D#9($+':07@":C.'9G%@E--67!@,.1=644D6(6?*%$-5G<GHD1D-4:B"-@C1(B;>!6=(3B#E,%1>#*2'DH:D>@1H#6;?H:E=%7@%$CB-#;.55GG$314>D-"=13@=BG=682F'<+?7$=,*A)56
@r4544
GCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGANGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATNGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGNAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATGACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCA
+
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
@r4545
TGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGNGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGANGACATNTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACNC
+
A#<-1EA:.#4A9#-E:1',:&!25-HC79><33:7*1;63)%4D6CG!.%/E9=@':0*<D)>1$*7!&+'8:0297??%51=BEC77)$,96&>65=B723<*2?)++E8#,2=A??3%24/.'-2@6'B*4:2C9!?6-+H:.#C8"%-G0.F?BF#%(9(HD%+0!5B@@:"*6*?54E"$=3G@*6!3B"29HG@#;9@B'4%)C9-((3F"'H3%(4/>;"$#(%&*)>$B)=?-C-&"6;4>259G77@A?4$5'(?.?A!**3(2/FD7&06D>>E?0G
@r4546
NCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCNCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAANACGCCGCTGCACCGACAGGGGGAGCCCGNCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGNAAGTACAGAATGCGG
+
#1.B76363%/,,*.C>11@8G(@AB/95-19(!.F/+3&+H?+#%'&6$-A&@1@B<2$C?&+A!;'78201+B59?3<34'/#--.1@.3%@;(4A9-,)>,4/10A49?=5*3F#?3A9!05)2:$-E&2B6.!CG,+:.69B!C+-9B$?1#=>HE5E76:
@r4547
GGAGCCACAGTCACTCATTGTCCGGTACAGCCGTGNGTGCCGGTGCACATGCGCNNACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCA
+
("8)4H6:?1F-'B=9C7-A4G/,1<@E8$'=8+FE@H-G:7.9D59<>()2?!#A7>:A7B"+DGA+3=?@$6?4)F00?>*@13.>11(*4.1"=".@B0E8A&;0,;A?<+?4B3?*B>-2++!B
@r4548
NACCAGCCGCAGGGCAACAGTGACCCGGCTCATATCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAAGGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGC
+
"+')&")%"$((+!$%%%$+'+!)%%*)"%'$#+!!#)$+&#)*+#&+(*")*"%)++)(&$$$""(+$')!$("*+++$$&)"'+()$+"$)$+)($'#&%))#!+&"!$#$)&$&%+$"*"')**)$+$!*)$%)$%$"(*"**
@r4549
CCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCNGAGCTCATTCGAAGCAGATATTTCTGGATCTTGTCATAAAACAATTTAGTGAATTTATCNTCGTACACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAGATGAGG
+
,"5",(<H&",9#8F?668EF1>5"&%DH0?;!$>GF;2EA)8A+-:H;-(CF>'<CEE-02G:=G(0A)-G03CD%++,E,2&+$."<9&6:91,0$2"B-(24@HH<AG%"3@?A$'H$"*E$"#23(+E"8H6@::,+D4#20,#E6CD*-;.DC2!*/"?(1>)@:2(!$*4C!/H?5!"2A>("1C?::$
@r4550
CNTNANNNNNNNANCCNNATTNTTCNNNGCNTNNTNNCNNNGNNTGCCATNANNGCNNNCNTNANGNCCNNCGNNANNCNNACNTGNNGNAANCGTTNCNCNGTNNNTNNNAGGNTATCGNNTGNANTGGAAAANNNNCNNGTCNNGCNANANNGCNCGTNAANTNNNCCGGANTNCAANGAGANANNANNNNNNNA
+
###"$$!!""$!$$#$##$!$$""#$#!$#"#$$$$!#$"!####$##!###$!$!"!"$"$#$!$!$"!$!#!$#""$""#$!$$!$#!#$"!!##!$"$!$""$""$"!##$$$#!#!"!#$""#$##"$$$#!!#!"""$$"##!#$!#"!!#"$"#"$#$#!#!$$""######""""!#!$!#$!!!!!#!#
@r4551
TATGACCCGACGGNACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGNATATCAGACAGGTTGAAACCAGCACGCGNTATCTCGGTACGGCGCTGTACNGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGA
+
0+7:A#0?0(105AD"@+3)=CEE+'5%2!E7F*(F!'#8=E962$3?%+*C-75/@=(<*?'=?3$&H39*7EE33)$4A8(6E85H18:><*>6;$;@/=H?3*<!D*H%;'&1GD(!(><'E@G0$E&,@=C?A.CB
@r4552
ATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGC
+
A&)/DD@','.7>C=>C!$#=G+0(858-CE"5&A>?7':+$-53@0@B"9+4&E#0.%6$>2,/4(9GCDD/.@$;3/FH'6H)40.F%@%'.DH7)6*E23.
@r4553
AAACNCNCNCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCNCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACAGTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTNGCAAGGGTAATGAGGTGCTTGATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAATAACAG
+
)$%*$*#(#&#'$)*(()*+"(#!)+'++'"#"#"'+!%(*#"%!"#&&+"+&&($+'*%'**&!&*&&!$%$(+!)"'($"+&&*&#*+(+&(()('+!''*&(!!#(&''"+"'"*'(&(""*!&+#%(&)+#%(')!'+*%#'(*()&!')$*!!%&$*)*(*")'($&(%"$$(&+"('+)#"+$*!$(!!(!&'!'(&&$#'*&"$&"%#%$'%"!!$+#%'&**'!%*++"+)#$***+**(&)"()*!#'&"##+(+"%!(%$+'+#"!$'$(&#!($$("'!"!&%'*$("'*)!)
@r4554
CCANTAAACNNNACCCGCCGTAGCGAGTTCAGATNAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATNTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTGCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTTCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTNTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGNCGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTNTACAAAACCGATCTCACTCTCCTTTGATGCGAAGGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTATTCCAGGTCACCAGTGCAGTGCTTGATAANAGGAGNCTTCCCAGGATGGCGAANAACAAGAAACTGGTTNCCGTCTTCACGGANTTNGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTNGTCGCGGCGTTTGATGTATTGCTGGTTTCTTGCCCGTTCATCCAGCAGATCCAGCACAATCGATGGTGTTACCAATTCAGGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCC
+
'#)(&'(*%!%#*()+%*%%$!'%(!$*!*)*&(+(&($(")*!)+(%*+"+)%+%&#"$++!)!**'')#"*(%%'%%)&&'#"'!$#+('"%&%('!#%!*!*(!*+%*'&%+)*")&#('*#(%!#)%''("+##)(($&#&%#+$!$)+!'#('!'#+#&%&*'*+%&+&"(+)!"%#+")(+'$"""++*!&%*"*$%'$)""!)*&*")+$(&!%##))%+(&&(!&+")$*"!)"(+"#))+&&*"%#!*("')"%+%!'%)(&&#%+()*)*#$*#(&'%&'*#)'*(&!)+&&$!*+!*'*+#(&&!%!)%+)$%$)!(&%!"*((#%#"+)#&%$%$#"'&"*%$!&#)++"$!('+'"*"!""!&)!+#!&$+%$*+"#)()'$"((%%'&%!"!!!))'!*#'*&#(&%!+''*)$#'%%)$*%%$')'&(!'(%*#)('+*!$!+%&&#+$'$(%&')"#$!#!)+$&&(*&(#(&"+*+#*+'"*!%#'%$!&""+!!$*''$$##*'*+")&$)!()&"#)%('+"**#*'+"%&$+'$(("'$&")%")*#!#)!%&!+'#(&')"#*!(*'!'%&*%!$#*(#!%&!$(++!%"'(&$()#(&)"$$#*)('"$%'*)+&%"+)+'*'(##)#&(+""(!%$++($(&$()$'$*+()%##+&!&&*")("*&"!(!*#%*$")#%*""'$#)(!*#%*%+"##"!)&$")*!+))''$#+($('#(%%"$#*+")!#++)#(()"'#&%$#)%&)++#")!$!'$*!)"(#!)%!)!(*'))&!+%"$(#*%"#+"#""(!())$'&%#*&+(!%)%)&"'*!(%%)%##$!$+))!)()(&)&*%#'$+)($"'((($#&#*#$)!*&'"$&%#*"')&"+$%%&*#)#*%*$&#+&)!+!$+$(+()$'+'!+#$()%&+*)(+$+)"(!&&&()+'*!%*$*+&%$$)%#"&')%(#"%#!*$##*#!(+)&#"+#(%!"#!#!)'*&**+!"&"!$(%"("*%#'!($*($'$(""$$'&##%+#&**)*&$)$
@r4555
NCCNNAACCGCCTTTGGCGTTGCACCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACCTTTTGCCGAATTTTTTGCACGTANTGCNGCCGCTTNTGCCGCACTTTTGCTCTGCGATGCTGATA
+
%!%"$*!$&+($')!(*()#)*('*+''++"$*&!+%&&))'+!)%$%!+(!'%!&&)))'(+%*"#)***#++""&"**&+&!$()$**!"(!)&&"!#"(+&'"'!&$%!#*'%$%'''!&)+)(+'$"''"#!!"&*##"#!&'')))*+&&&#&""#+**''"+"!!+#!#&!"$&))'!*%)*#"%&%$#+
@r4556
CTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGNAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTGCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCTCTTCCAGNTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGT
+
%@&B(F"BC4*59#)2.&)1)96H'#:E/437@9+#3%G0,>H-G62D:@.#)8(-0?9*#F8+/1E+41/>#F9.=70"F%H6>>F=;;8='@%*:/G#&>G<-*66!/0.4$%,%*1(+2($#+$$"<69:6<<GH;H8,%4&7"*(,-F(,F@C((((!).6/E@#49/A457.:277E31B=A618$10)EF%476-%60->?FE=G0,?;?'.4(/>?:#.9H9AA3>E&0/8E"<G'<7>A>.(H8/>G8-*10:8:+/=G8CG6DB8#3,><!2"'GC@B39&<C<@%51;$@-9)2!0D=6F&C&G12*<>B'A>*C"30*'(7)+D90)8?7,C
@r4557
CACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACGGAGCAAACGAGAGAGGTACACCGACAAATGG
+
E/5.(E#BF1H(!<""!.666'/B$4<A!=3.A!6G&DFFA0/-6+7)>,24&B%?++FG8DG+-67/6B974.8(*@G@%.B</05>1,/89E<9/HEABE$@2C.BFG035)(;3:'-!&)G?DD/,<42>*!/'
@r4558
TGGCTNGTCATATTCATCCGCGACAGCCGGACCGCTATANCCNCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGANACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCAGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGGAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCC
+
@'2E%@$,$H<)8C4#/'<.=/A.",5';7G!5+5&:"3&HB6?A:HH7""B?@F)@H,0D#GAB!3#H#/:4$(=?A0/>.'7#/B?:!>/GC@7;;%>,-65'A-A*6;921G5-EED#H*?2='@?AD*=@?5$15@!<-G<.D$;-,)@2?C<)(B'B-15E6F&9/((7=6+$5?#,HA*F'.*A0F/=23#CH4C:@=<@0#?;"'DH'<$BA=*$"+/AE?F?.6?C"/;5,"&-C1>04=,=FG/9?>@3G<@+9@(E?*#B@6HA/E+79.#/=HB,$4:,#9*E;18'C(12%,-@.,6H;C6BE$$-8)G.4B9F8-5;2A+2)9'"FA+-D5&;),/(F-=&2AEG4)=82=&5%67#(%/46
@r4559
CTCGTANCTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTC
+
(->"G-G(0/8$"7@@;E7;,"-B*.8-5"F='4D<2,/C-5';(C&(:FA35!E:
@r4560
TGAGNGGNNNNNATNCANACCTACNTNTANGTNCCGNNNNGNANNGGNNNNNNNGCNNGNNACNNNNNGCCNNNCAGNNACAGAT
+
"$!!""$#"!$!$#""""#!"#!"!"$$"#$$!$###!$!#!"$#$"!"$!!!!!"!"$"""#"!!!"$$""$!$!#!!#$$!"!
@r4561
ATCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGGAAGGCCGCAGATGAGCTTGTCCNTATGACTGCGAGAATTAACCGTGGTGA
+
$"0%;DB,3B(2':AG%F<+6%-*;8>9:!*/!F>:4G7;.$1:;<DG()5';58A"7#8$395H0A:'-8G>D"FD!+84$H35/F$,'8B$)5*A'7"$34%6.6
@r4562
TTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTNGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAACGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTT
+
.GA"03$#7);!>DF:9'<:+A+,?B726!431C=1*>%H$%F.G$<&'%=3.6$C571/;-F&B9(0D&'1/C!D;/5'EF:/6B!..(2?,871H8,967EE9&4=5@>A&6<C&3F@B62/!<$CD*/2"3)!"@CC%A-1(6C.7"!=C2@>>A%&.F&H33"%A<B40*':1D>+@G%7F26#7B%=/('".!0*?*;&7=:87H730./=(:7@%63BE,E1B1:C%$A*.%7!4;?(F<,2D"943#3E7$4&0;>;68B%9=&9/0<$&=++<@.8!(8#:5!'5FC%=92E0-;219D#*E5-!!/*3F1(-!.=CBD*$EF$/AH/"$2(%+(&75("HEH)$A?06#2&BC4!2">8(3#&:
@r4563
AGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCNTAGTAACCATCCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAANTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCNN
+
0B7*C>@3+*=HE0H)EC>GF53:+C/A!1,%.>3A,&16=*%..+C)F:!#"56AD"BB)F,E0$6!&B/C@047,,&/)6-*(7/>D$?C5E'),1#<4D5@4%B2G7AH#:/2@4;5$73=;6A=/"-5H800(3@8:B(A3+03(*HD>/4@9.*>'-8%/BA!B36BF9"1B,@C?<3B$!"=C3<8B+C:,6('4=0E1<.9=A4$51:D4=@(!";9F87C@D;(=<8&H,)2,C=A3C',H(E56E(1%A!>!2C->-D+:?(:F+;>=18G3C0&%9!E''"7*
@r4564
NACAGGTNTNNACNTTAGGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAAACGNTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCAACTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCNGCACGGGNGCATTCATTCAGTGTTTCCTGCCGGANATNCTGCATCAGTTCACCACCTNTTCAAACTCTGCGCTGAACNCAACACGCAGCATACTGACCCTCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCCCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGNCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCGTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACANCCATACCGGGTTTCACTTTCCAGCGGANGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCNCGGGCACCCTCGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCNAT
+
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
@r4565
TNCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTA
+
(33-HA>0"!E=FE'"*6.:=+C!8-*56==F*<#5/)B87=0;(,6#F!C#+GC%,#*B/*=!%-%?;2H/&H0A8?C>3E7%H5H)DB76&F)@7*?(181FC,@5()FE9G9E8&=A-*BE:<+<10@.7#3"&#</
@r4566
GGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAAGCGTGATGTCAGCCTGACGGGGACGAAANAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGNAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCA
+
DFE#A2!B=E#;!H%2@7;G/B#(02C2EG98<.6&*#0/?--A3?:B/-%#02&<"5-2!3/0?*5C?2!D>+4*>!)4&3/97E5>'-;"E@:/:'-*-E=DH;DB54+6,F"$8-A=.='/*5HA,":H$,0B5F!/*D@>2"F5A"G@%D7'+83D%:'H!9-+F52/#9%AE=FHE7=-5+H*&93DE+>=5:H'4E5A/00#1*A3G$
@r4567
ATGAACGCGCAGATCNCCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGCTCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGANACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACAGCGCTGGATCGNCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAANAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTNCGTGGGATGGCACCACCGACGGTNCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGGTGTGCTCTGGCCGGAGGCTGCCNGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGA
+
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
@r4568
GTANCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGNTGNCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAANGCAATATTCACAAGCAATGCGNGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTANACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAANTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAA
+
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
@r4569
TGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCNCCGGCGGTTATGNCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCNGAATAACCATGTGGTGATTAACAACGACGCCANGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGCCGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACAGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAANGAATGCATCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGT
+
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
@r4570
NTGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAACTAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCA
+
#&.#+F;=4-".HH8&62F/@E?AD"?9#?9C&4B37F31!D'H14CC1)5'A6+,7#%=HGC9%15*->$=8*3(>!6"&"F>*4//(9#67E9#FB,6&<$*7>F@):2.C$"
@r4571
GCATTCAAAATTTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCCGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTNCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATANCAACCGCACGGCCTGTACCATNGCAATCTCTGCATCTTGNCCCCGGCGTCGCGGCACNACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATGAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCNATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCATGGT
+
?B"C;4H16G2G;@DA(F%&('2#(4%7G;7(HB>F'%B8%?$%27"H&HB$45H25F)5E,D!$==(9G8!'7H"2@2+,AHD'?,B%?43HBD$6=6?!#E??G@8+C0;<<!!9E&853-<F$4@G$F5AE3-+6B(&#%A;0=B;E.%"G;16A??!79BH4C5.E*8GA=(/=<<0=27;C,&<(6:&H7A0;"F9H4$3;%%%5"1840'4H>H':;,"B%1!'>.0,BB>F!@?5(%0+56B//G8-E:CB%D4(:'B.16<!@B&!13,?1#B/*0F4<-&-%%,.46=%7.E-)"0!F(*6G'!4D'5F0,/A6.0/C+%@5F6D-3(1%'3/1/C)G&%*3A71EC:$!FD)E"1='?09%;GH;5<.?0"B(,,*&B6.-5)!>G-;5"G!5+$&0B69A<"+)":@<.7D9?=')84!0@;,:;9>6F'B">#">8>,E1&/6)@+H6*BD-%%97>68>)%%7+9/5*$/1&22E/0+5=@8-(H.(#G,1/89F4$@?+F",?<+EF4,$H@'!+4F?!'!'C5!9#&#;3(>#-B/.
@r4572
NCGCNGTGGGNCCNNNNACGCATTACAGGTGNTGCGCNGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTNTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCNNGTCTGCGGGTTATAGTTCGACCGCACNTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCNCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGNATGTNAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTGGAGGTGGTTTCCACCAGTGCGTGTACACCGAAGGTAAAGCGCAGANGGTCGATGTTTGCAGACGTAATGATGCGGGTGATCGGCGTGTCATATTTCACTTCCGTANCCAGCACCGTCTCGGAGCCGGAGGATTTAATTCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCNGCACCGGCGTACTGTTCAGTAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCANCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCNCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGNGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTNTCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTGTCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCAC
+
%%((!)#$&("#"$!$!'+"&&+!'+&$'%""(+&+!"")$!!"'(#&++$+&&+$!+%$+#)%$*)$&#&+))$"!$(&&"(+%#!+&)))!#')"!#!!(*'""#(!'*#'""!#*(!%##$)(#*'&'!(&)'(!&%(##!(+$)()*$''&+&&)$)((++&+%+##%'!&)(!'"(!*)$"+#)%***'$$%+#)!%!#'!%%#)$*'+*)%%%"&(&#&(*()!()%$&"%'(*%*#'*'''%!"+$")"*%('&#(&!##%$!#(''*+"(!#*+!*)""#(*$(!&&*&#"*#%*(%!&))+#("**)$('#)!"(*&)("&""(''!$**))+$)#"!$&"&%%**&''()!"))"$%')#!#""+!)"!&'&)"&''*)#'!#*#%##$("")#!&)!')!#%!%#*('))(!)'(&*)!%+$*+&""*&%#')!)#(%($)(&'+*&*!%""!&$(#(*&+&*%$&(!$%*#%&%)###!*)&++$(#&$&"#*"*'*''%$)#)*)%$(#$&!'($"'*$&#!$+&("*()'$')"&$'%'%'$%)%(&%&)!)(*)&'!!&$!((*%('&&(*)'!*'!'#)"!#"'"'")*!#)&&'+*(#(+(!&&+"")$+(!!)((%!%))+&("&%"%&)("+)&$*$'+'%#!&)%'*""&&"%#!%!*#&+&*'%#)()*#+#&!%*!&%++#&&(+++#+!$'$&")!)%#&!"%+#%''$)(+"%)%'*%*!(%#"*&(*&!(&)%+(&!%*+&!#'+(%!+)%+'(%'*'++%('&")(%""$&#&$'#!&'#!%(()!+!""%)%#"'*"'*%%#'%&#))%#%*%!+&+"")#+!#)*!("+&%!$)"(!+&+++#!%+##(&'))!)'#*$+#$(&")!&*&('*+)%+)!(""$!$'&&#'+'')(%'$+&&*&)))'%%#$+)!("!&!+'%'+*&**)(()*++'#&"!#)&$)(!#'!*!%+#&%#!'&$*#!!'#*!&)&+&'"*%&&*!"*%#*)*+*#$**"(+$("+%%%#(""!$$!""'"*'"#"*")+(""$"'!%"&!()'**"+'$!+(&+*)!&+)&"'#%'&+$''%&%$+&!)$*+&!!$(%))('#'+*$'('"%%+!"%(!!!'*#%&!'%!#!'&'(&+*#$#!''#%!$!'*"+'*#'"!$&)(""#*!"&%"'!"'+!($*+'$**+'%+'"'"!#%)+"+"'!%&&'#!$$'**#'&%!+(*(")+*&!"*&$(%$''+(##)"!'%'#&(+!!%"&#)%$"(
@r4573
GGTAATTTCTGCAACCGCAGCAGACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCTGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTNATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATANGACTCAGCGGTC
+
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
@r4574
AATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCNCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATTGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAA
+
-:,%A$>//&,"E44A(@D9B8?B<1C+$(4=?&&?C5@<A521/66;2A5?9CBEF&C'?37'.846+"F+6,@27<3'209C=&=+27=;:<&;<<G#3B=#CA!/3$C5,<@$6*7'>!43H<HA#&.,:2!889,02(B51>)7E>AB.&0%1=>@<((@%;4D#31870C(;,H&$4C?8!9/570(5E%.,@G".*GH#::G33B;;H%8B?<!$8!
@r4575
TACCTCTGTGCCGGATNAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATNGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTGTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCNTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGGGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCATTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTNTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGT
+
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
@r4576
NTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGG
+
!2@0?76%&2?>6<4D.6(CD;(4.7BB=2*;"DC$>7(-G/*+6($6(F5B$<;A8*%9CEAC94">1=</%,"6;*DB&-A%!12F6.@H63$,>D+5*%,;D:/,*-$
@r4577
TTANGATCTCCTTACNACTGATTTTGCTGCGCGANTGGCAGCGACATGGTNTGTTGTTANATGGCCTTCAGCTATTGCCTCTCNGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATCGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCA
+
)!$)$&*%)%'*"&('$+'&"(&(%)%!$$'%'*&$"&)#+%*&+*!)*)&$&&$()+(#*"!+$+)!+&&)#"+*'$'")&#'""*#*'+)&'*%+)&$((")'&+$%(*))%+'&)*)(%)!*$+')!)!#%*#))!)**'*+(+'+#!$()"("+(!)"++(!'($!(")"'!')!*!*)%$)!''&(+%)*$&(($'+$%++
@r4578
TGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTNCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGNATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTC
+
&G"()HC1?GGG2E!<4'-D=8B@F"E2=-=D:(A$<DC8/)0+**2#,1*@A136)/%#D)F@D1.E:$.4D0385<C?<D(ED:)EF2+9D4D*)*"AF9,=/(>%@+6D="%B<=)5&#).-'#(D7&)"5@FF).("(149<H.<D1:6.,<85B>@$GF7-.=98$/63@<5<&,CB#'-.>)H,D3E0=%B#.184G(?%
@r4579
NNNATCCGGCTTGTGAATGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAACGAGAGTCAGA
+
$!"+*"%))$#%)&)(%$'$))(!$+!"%%'+!""*#&(!')!"&)!$&!%$(%!(+#!'$')$'&$
@r4580
NANTAANCANACGNTTCACGGNTNTNCCCGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGNCCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCCTAATTTTATTANAATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTATTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGNCATCGTATTGTAGTTTTCCATATTTAACTTTCTGCTTCCTTTTGGATAACCCACTGTTATNCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTATTGCATATATAGTATCG
+
*))$)*!*'#&#'"))'$#*''&$*))"'+'$%*##"+))!$"$'!##$)&$"'##**!%')!%)#"#$)""))%%()"'%!%$!"##*'$(%#*#!#%+(")'"'$$"*$'$$'$+*$%'*+"+$&*'#)&+&'%)"&)*#'%'%'")"$'+(&'"%*++%%"))'*"$&")%!('"#)!'*#%#&'**&)+#%$#!#'*$*%+"+##!*#*")"")'!#&+'($&$*!!++()*'""+%+&($+%"'$!**$%)%(#))$%!)'%'$"$%*%'%'$*!("$)()+$'+!)"&"+*$'**)!'%*(("!$$('"$"*+!+)#"(!*&$&#%(+("')%%(!*#%%*+"'+)&#"&*#'#&&++*+'"+!'!*'%("'++*)*'(%#()*!$#%*$'+"$$+'')&!!!*##"!))()%%'(!&''##"(#+'"((+!$'%%!')$$(+(%)'&*#"!&*'")(*&)$+#"!**%*'")*#+$$)+(%%"'!*""#+)%&'
@r4581
TANCGNTGANNNNCNGCNNANNNANTNNNTTCGNCNGNNCNCANACNNNGNCNTTCAANANANNATNTGNANTGCAATNGGACCTNNNTNNNNNGTNNNNGNCTNCNNNNNNNNTNTAATANATNCCNAANAGNAGTANCNACNAGNNNAGNTNNCCCGNCTAGNANANNCNTNTTGGNGCNANNNACACNNCNNNGTTNNNNTATTNNCNNTNGAANAGNNGNCTNNCGNANCGACGNNCGNTNNCTNNNNCTGTGCATTGCGNNNCANAANNNAANTCTNNNGNGGCNGNNGGTATAANANNNCTNNNTNNTNNNNGATNNNNTNNGTGNGCCANGCTGNNCGNNNATGANNACCAANNNNNTANNCNTCNACANNCNNNNNANNCNNCNGNCNNTGNNGGGTNTNNNTANCNCNNANNGNCNTCGNCNCTNNGNNNANNANNCNNCTTNNGNNGNCNTCCNAAGTNANGCGGTGCNTTCNGNNTGACNCCAGNANNTCNGNTCANNTNATNNTNNAGNNANNNTGNTNNNNNNCGNNNATNANCCGCACNCNANAGNNNNTGACGNTNGCNNANANATCTGGTCTNNNGATNNGCAGNCNACGTGTNNGAATNNNNTNCNGTNANNGTANTGANAGCNGCCGCNNTNGACTGANGCCNANCANNNATANNNAGAGTNGTANCNNCNCNNTCNNNNNCNANGAACGNCNGGCNNGNCNNNNCNANNNCCNANANCCNNTNNGTTGTAANNNCCNNAGCGNGCNCNCNNANNNNCGNATNNNTTTCNGCNTCCNCCNNGNNGGNGNNANTNNNCGTTNNCCNNTANCNTTACNTGNCTNAGNTNCCNNCGNGNGNCCTCGNANANNNNNTNNCCCCNNTNACCNNNNCGNNNNGCNCNGNNCGCNCNNGANNTGNCACANNNCNGNTGNNCACNNNNCGNNANANTACNGNTNTGNCNCTNANANNCTNTNGNANCAGNCNNACNGANTANCNCNNATGGNCGAGCGTCNCNTGNNGGNNNNGNANTCTNGNNGNANGNNNANCTNNN
+
"$#$$"#$"!"!!!##"!"""$!$##$!#$!$""#"$"!##!#!$"$!##!!$#!#""$$!"$"#$"#"$##!#"$#"!"$!$#$"$"!$!""!"""!!$$"##"$!#!$!$"!$$#$#"#"$!"$$!!!!!$"$"!!#!#"###$$""!"#!!!#$$$$##!$"!"!!$#""#$""#$!$##!#"!""""#"!$"#!!!##!"!#$""$###$"$""!"!!!#$$"#$""#$"##""!#####"!""!!!!!!$"$$$#$$!$""#"$!$""##!"!$"###"$"!#$#$"!$$#"$$#"$!"!!"!$!"#!#""$"!$$"$!""#!#"#!"###!!#!"#$"##!!"#""#$""##"!#$"!!"!#$!$$""!#!""#""!!$!"$#$$"##!!!$!!#"!#"!$"#!"$#!"$!"$"##"$!#"$"#!$$""$!#$"""!!"!""$"$$!"#$#!"!"!$!$#$$#"#!!$$!$#!$!!!!$""##$$$#!!"!"#$#!#!#!!!#!#$#!!$#"!!$""#$!"$$$!"!"!#"$!$#$##"!"#!"!"!"""!#"!"#$""###$#!$"!!$!"!"""!""#!##$##$"#""!"##$!#$""!!!!"#$$!#$"!!##$#!"$$$"$"#"$!!"#!$"$#$!#!"#""$#$!##""!""#"!!"!#$$!!"#"#$!$!"""!#!$"!$$!$#"!$"#!#!""!#$!!$#!"$$$!###"#$#$!$#""$$###$#!"$"$"$$!$""#$#$$$#!!#$$!"#$!#$!!""$#$"#$!!####"$$!###!!###$##"$"!$"$!#$!#!"$!!"$$$$#"$"!$#!$##!!$##$$##!"$#!"!#!$!"!!$"$"$!$"#!#!$#"##"""!$##"#$##!!#$!#!$!$$$"!$!#!"!!##$!!"##!$$"$#""#$#"$"!"##!$!#"$"!!!$""$##!#"$$!#$##!#$##$$$$"!!"!"$""#!#"###!##$!$#$$"$!#!!!#"!!#""$!!""#"#"###"!#$!!####!#!!$!$"#!"$#!$$"$"
@r4582
GGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACNTNGCCCGGTACATGGCGAAGNCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTNATTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCGGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCANCCGGGATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGNGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCTTTACAGGTGTTGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGA
+
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
@r4583
TGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCCGGAGC
+
"C:0#?C/HCF02/C(=#!.,DA@37BBG)06$4)-.:,96*H60'B+6,$38=H=/CG:3BE02EB!AHE3F>5F*-BH@B0"@<3>6"6C)/9=C@*$)BF@)?70(>D/=C4&4>;9>A'#;#'G<@F+FC?@G5:748G+B<-%G(:
@r4584
NCTGCTGCGCAGAACTGATGAGCGACCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATNAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACAGGATTAAACAATCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTGCGGAACGCGCACGTCTGCNCAGTGGGATGCGGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCG
+
"(+!*$)!%""$$(+"!$)($()$'*($"%"$!+%+%)'(+$"'+&#+$$#)%%'!+$+("*)$+%)'*%'*!!!#+$#++*%#!)+#("#**&*&&#&+#%'+"&'((#*'+*"*$*!"$(*')$*&+"")*&(!%!*"&!$*+!#$)"&(+'(!&'!)$&'%(&#"$(!!!$(*$$!(%#'*%"$++*))$!%#''&)+)+!!&+$'!+(#&$))'%$'%"$$++"("#(*#!%*($*)("%)%$(!)!$#**!%$)**$#+!(#"'**'$(*)&*++")#%###%!%$$'+#'&+)%$+()+**)*%+)$!)'('(!!+))%&*+!#%&(+)+(#$++$%!!"((**"*&&*''#(+")+&&*)*!"'''(&$%%#'*$'*#&+#)($!!'#&*)%#!(*''**)'&"'"%+"&($$!"#!$"((!+'$')
@r4585
AACGGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAA
+
8*"=H-)HCA955=&49BG!91((D?>/@9-H;B=.G+(32)8/B1+7:65(F(>7/=/-HGF)"H"97FH%H;)3%$C;9'(A4%&&=!(0-@16<0%%*=*GD>!F<?4+=(2-&>7"'B7,@C,C2.266'=>%3B"*;<3D9+*C*A=!C'!+.:-<,E?5<8D,-,%)-9FFF!0;+37<D0-1@FG-7!/?D-G3#9;>9;6%'/#9")(G$;$%3-%:F.6"1E<7)E-,/,:H:%=+F?00;B9&0/GH2%:,7G-")>'EH%C(:,6(28":BC827.<F*2F%4%B
@r4586
TGTCGGGCGGGGATNCCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCNTTATGAGCTGACGGACANTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCA
+
D/04'6*<D3?(=,##9?"D,G<?G9D?5G%9<>G=*-9"%;&098/;C,"**6H5$=7=7"89D:-,)#D&1./6)*:+.7?!%&"@;>@!13'!C0.1<>28@2*;B?72*3<!;1.'FD9"9C@!?H)F;,!ACB2$36-+#0F=E;;
@r4587
GATGCAAAACGATNAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCANTCTATGCTTTTGTGCGCAGCCGTTAATGAAGGCAGGAAGTATGT
+
5@9%/B..3>2E8/%-G%-$%1/D615D1-FHF,3$$5"'=>8F+*1@/2;',B"E$-BD?.5,$C.6*7"B$=='H"C#"F2#&?6)(1A231&4
@r4588
NNTCTCCACAAGTGNNGCAAAGACNGNAACGGCAATACACACATTACGCATCGNTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTG
+
&!*&%#)"*)*((#""*&)%"$((!""+*(*('*!!+*%&(*#+*$%)%"&#"!)+)++"$()"$*+#'$!+)("'&"!#!'#(#$#&"&$"$))'+(#&%!'#
@r4589
CCATCGTGCCGCGACTGCNATATGGGGGAGAAAGGTAAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGTAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAA
+
442@#94!G?8%<F((=2DA&7&G0D1/"#=CGA*!&5-.H<D!GC4)3H5-7?@AH;&=14&1<>92?:F97$/<4F/1*2!69.,#;,,G-?(.2;%8&595A6=G4126!8H@.D3+/0):&#@6-'7C=#:F"7!,7>'76=CH"6<7C(E3;>+=*DD;5HF63EG*&.($1/#<39::7<8$?F=>(/1,F18,.9-;(:F;*AHB"*!;7;4B8H<!F-$BA#9!H"H&3510$>-"%$$<(#D$=203$>2B=/;:$:,*"%)*+=E7
@r4590
NGAAGTAGCACGCAGACTGAAATGTAGACGCGGTACGGTCAGAAAAT
+
!%+"'++%(('(!$#)(#)"(+!'%(#"%)$#+%&+)%"#&$)*&*'
@r4591
AANTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGNATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTG
+
0G9'>/E<6.D?,#$G5$E)%F8%A<%)F+A!.9,+C:AE>&#$7,*;;8HB1-0,:$#E@=A829*,/.8&88+5<0;F5A"(/6B6%?!#1+1%:=41->!.$.;+FC:G9
@r4592
CGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTA
+
1@1+,C&E!@?>$A<3)DHG2H90?.#".;,,!%C2+$/6/)..!!"?/"-'$#=DG;C(E>?H3G08A(;H/8B9?:H#81<%#
@r4593
AACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCCTNGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGNCCTCCTTGTGTTTTGTTNATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATNGGTTGCGTAACAANGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACNGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGANTTACCCTGATGTTGTAATTGCATGTATAGNACA
+
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
@r4594
GCCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACAT
+
&E1.:?E$4+!:24.!-@!9#%-2.4-(8E!&D79'%.G354A6H@8;&A&!C'(;:5G,2(F1($B/,+7G*D&9
@r4595
CCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAANTCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACNTCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCNCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGNATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAANATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGNGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATNCCTTCCAACGAAACGNACCAGANATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGAAGTTACGAACAAAAAAGCGTCGGGCGAACTTTAACGTGCGCTAACTGCGGTCAGAA
+
($+!"*%)("!#($'&#&$&'(%+'(&""!#%#*#)&"()!$$#'#!)&+&&"+&+*+!!(&(#%%$%&+)*$)+!*"+*&+$%!!!)*"#++!&'$'!&&&#('"%#!%+#%#'()++$"!%%*!(!'&"!*"!#*)&)##!'&$*"*!%(+$''(!$+&)*&!'!"%("#!"(%(+))%##&%#!&&(+"+*!!'(%"++$)"&%&'!("%+#"#!+(())!+(#%**$*+#+$*'&)#*$!'$##(#($#$&$!+!"!%!'%%!'%+"*$+#!+(*!#$%+''*&+*&"$!&#%%()''!!*%#!+&&(()*&!)'*$)#*#$%&%*'#)+(!%!"+!**'!*)+)'&*!$!**)((')('$+')%')#$!%+"(+!$'(!&!('%&%!(&+&%+#$%%*)%)++!&#%#)+$)"*""#"#&)"(&%%*(&"%#'!!"""!#'$(%'!%&'!!++%!$+(')&(&"*'&!(&$*&&'+&'$*')'))*+(!)!*'%!)(%*%"$"(&&$"!'(&%(!(")!$#)'*+%!*#)*'*%(##%&#%&+$+%!%)+($!#*&"*$!""#!&#)*&+'!%%"+$$&+*(&)*'#(&+'""+++%"&+")(&+"))*+""*&#(!'#$'$+*($!+&$'"(%%&$!%*$*'**!($*)&)#*'(*&!+!$))#+'%%'+!&'+))&++')&!))#))"$$&())"*+('###(#&*("!(!$#&+$#+'**#*!'")((!%*"%$!&$"($++("+)&+!$+')$%+#('!%$+&!!"*$"+($)(##&)'+%)+$%&#%*#+*#%"#%#!$(%
@r4596
GCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGNTGAT
+
>$C9A0!+"%"7@B6:<6(#EB8@H##5@(+'*<&09?6#4/!!E17>!
@r4597
TGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTTGCAGGAACAGGCAATGCCCGTTCTGNGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGNCTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAANTTGAGAACGAAAAGCTGCGCCGGGACGTTGA
+
&).?/#A#;*:>&'";0?%?75&==<5,HB*:/(4'F'*>'/'2E-1*:2(,-B:78<D8*<#3G>>D%*:93-B9?,'<>@-+'885?3E=;E?*B0HEHB117$C8H*-*&3/+9(A4*3G+A12B!H+61BB0@87)&,:$,-<%3";/<1;/<.<0*=29=G#)H#*;&FGG'-"E:F6%726"A=>;.AA7,#80G4(>8'>:>.3(H0&0)H4B91.
@r4598
TNATNACCCTAACCNGCNCATCNCTGGCAAACGAATACGGCGGAATATCTGCCGAATGCCGTGTGGACNTAAGCGTGAACGTCAGGATCACGTTTC
+
(%'"$%)(%'$'*(&&%"#+#)!%'#+$$(!%&"%&&#!+*&*&*)*&''#(!+#*'#+%*"$'"&+*')*)"("%)*#++)%$+""#*($&&'!&
@r4599
GCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCGAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGA
+
=/:721+(<?'!=F$4%C:)F;?&:55-'A9$80GE"-("FH,7G%5*,$<%=*1'!B2'GG!B"F@6-7=("!:9&GC6(:@-DE+:$>D2->G:?.E$-7"G!''A*;4)4")"8?64,3*$7%1=59:<%10$#:H=/G).*7B7"0:9"@$84*'$#!3=6B965/H!H=@#CAH$F@1%/(',/6%=+/18"E7!9,,G,99?2=/*H8#64!$+EG0*:$2;/)/44B4$2%EDA!HE=><4AF9<!E%;(*-.1=93$)CD(<9(*5**7..')8@3%@F7C$7H:*-2G><#))29<@>'?&C*1-0;B9/5&BC)B7;A0A$:A?89>*5%"$"7@#5EC98<$=;%4">)!-%52/FH,%##C487+8-@'H-?>,&40!"'$.7$40:+59/'209&=>@,
@r4600
CAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCA
+
C,>2?",2&G;8%';'3GF@%*D-5F<'673!"*=/,"0<ACC'.="7H/634>?,G4,:)+<G!@1>5"+A428A26B85:!!(DF6H@"C82//9=+"*D5#,'.@:5*:7D60?5;G-E.C1@);52!+A00&8*=#(:5':07AE#@*)57)!-(-1)AA'2>3!"/*(-84>)*"450F@A-HD2=(648.)FH5";B:E-C#1-!EA%G*9E'':C44H78*=."G%*.'4@0,A$#G7.>:GH*%B%:!"1*.H(;F8%,6'+@F',H-&:4!H@-
@r4601
CATATACATCAATTAAAAGTGATGAAGAATGCACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTNCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGNATAATCCTTCATATTNTTATCGTGCTT
+
,4#!9@$:1=&1.E+66-835!(#2/%5-*C=<A"DD"GA@%,E/H8A5E)9@3E4"%4'EG!E/E&'91$B.<#1(.F!G#>!:;*>&/A#5*9B6C<%6693=$F"$A<3#;1G?&-B,<F;+"#E7A0)588*'C039H8&G?2$3!#G)777&!;""*G73+HB.);*?&>+E=##&##A=G($.,;(=>FDFA#,290;7A*(%'HH@&DG3.)987,?C?<0!H,>@&A<3;.E9
@r4602
GAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGNGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTNGAACAGNTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAANGT
+
F,38DBDF0#*9F*<-</,4*3,"0G-D/+>.DC"F4</.#$B9)"&772;@.225CB.>F*'A07<#H<'7D$&$*-BDE0<5C>>>D'>9/9$3*998!$:7;?9/26'183>A,'H(6E>!8;A=4/>>BA9<5,?(A"4G>#($766&C;%=ED-+1#)@$B<;H@)*G1@?8<,"?+;;BF,7H+!/./77G<(@+FHHH14%6:B7&/+:F$485C34&(*'?64F#@??.0.3'<38H1D)634C>1?*;5;@B4"4>!+A?).H(6<>!=@!?+9773%7<.15=54&GC=&%@$?;G9@*76(
@r4603
ATAAANCACCGCANCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCANCACTATCTGCCGATGAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCNCGCTGGCGCGGAAAAGNCGCGCTCGCCGCCTTTACAANGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACNGTTTTCAGCTATCGTCACATTACTCAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTNAGCGGTCAGCNTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCATGCGCTTCAGGAACACGTCGTTCATGNATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCA
+
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
@r4604
GCTGAAATATAGCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCANGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGCACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGNATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATANAGATGAGACNCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAAAAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCANCCACGCAGACCCTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGNCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGC
+
+"'%$")')))+)&*%$#+$$*'&+"#)++("%%%$*'$'*+*(*#&(("&*$)$"!++%!)&%*$!%*'')!+&$*))+##*)')%(*)$#++$$#*!"&*#!#"$!"!"&($&#!"$$&$&##+)%#(#)+!")$+%!('$((*"%*(+*#&"'&!%)(*#()!(&*'!)!+%)#%''$#$"%++$#"()&!#!%!")#!+(##"&"()*"$)""%!%#($)!'*#&*)("+(!(&(!$%&*#")$()'"&(!'#"&+&+$#)+&+*+(#(%#("*+*)++)*%!!*)&*++#*+%('&##!()"$%'%$)++%$$"(&$'(()!"('+#)%!(**'!+#%$+&"&'$!!!($+%')%"$%#"%(+))+*+%)")'""$!%&#!&*($*#*"+&#')*+$($$!+#$#"')&'+%+)(&'$)%)&+&*'+#*#!()$"("'%#$++#!+)'#%#)+#"&&#')#''&(#'+'($+#$%''+!%&)$+!)'$!$*+)&'"'&&%!"!'*(&$#'!&*$*(+*++('+%)!&#"$'!#$+%)!!'!)"()'$%"%+&!&'%)"(*'#+**!$#"#&)&($"#+*#*'+++**++(%%)+$&#&$+!)('!*'!)&)&)("$&"+#%")+()!'(()&&++()'&*$)+)!"!!))))$+*#$'))"%+%"##&#!!$"%$&'+*%+&'!+%($'('$#""$%&!*)*(*&#!'*#)")%#+$'"!#'"("($%")'#$""#&&!*)%"%%!%$'"%!+'+%!%#*#'&"#($!()+(&(()+%+(%$+("%+&&'%$#**&%&+$"'%'&(*"!'+*)+%#%&#*$$")$&+%$#%!&)&%"%(%#!*(&++("!('!"$!(*")$&#'%*&(#%%+%(&"*(&*$'$#$$%'*'%'%&*+&!+!+%!**!(*%+)$!&$$$%'+'#&%((+""+)#%)
@r4605
ACAGNCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAANAAACTAACCTTTGAAATTCGATCTNCAGCACANCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATT
+
;-/!@:-9:AG/2+,4$.0&2C/@A%A!!=G#G#=;AE(<./+363FG#=)7G-"G,+"D=41*D5?)H/59D&"/+G'>G"B*E<3*E<)F"#@B<?5/5/'C9)B5,$0B6/$D,:8,*?BH;="#*)-8#*9(162?D10"@06",3.*#+%
@r4606
ACCNGANGNTGNTNCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCNCGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACC
+
("&"!($*#*(%''+))$"$"%)#"&(%+(*!***')$'!"&+'&*+!'&$)'#+#$!%(#'*%+&$'**!&"'(+!%'%))(*!*'*!#!%(++#$(+!"+&'&&&$&%)))#&)++!%*#
@r4607
TGNCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGNGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGNCCTGGGCAACCATGTTATCCAGTGAGGGGAAATAG
+
C%3/E?9=0,%#6*#A%&7)H6*5,+'!4((H)1*#C$0,0>;C@!:88BA1'.H;06A8"->>(#!C-5".#/&$*9%@"H5*3*'7=$+->>HAG5'/+<&0H6!*=C<C9G1%A((3*/E?@/-:E.D5(F;!-"!/1&,.#89)G'&$@=B6,GC%#5<!"B3"'#F-+?-,7@313/B0C4BG>$(=%,!F>4&D;.@()"9E$H&H3!/7%>E.99B+<9<;EB1;%;>!1
@r4608
GTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGAGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGACAGCTGGAAGTGTGTGTTNACCGCAGCATTAAAG
+
0.>@.*>2>3B'>-@#-;F=.(&((/#A+):)C+@(/0?@6;GHDF#?2?)<26"C1+!="5&>%$.!F:$-CA&$C=D)A8&<743;!7ED*9%B5F4;G%;413,:;B>"75:"0!0)7?C5+D2@/E:>;;4:>)2**#B@
@r4609
NGCNNNCGACTNGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCCTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGGGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGTAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGNAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCA
+
"((*"!"*"((%'+%**&*$%!#"+%'$')!'#'*%()*"+)#!'$("#*'%"%#)+("("()+)+#!"%#'$!((!("''$#$%!#!**%+#&*!)"($")+#"#%+#++++*&%#)"&&'$*+*&+#*"++(#(+"#'&(*&*&!%%##$!"*+%$*+#'&'(#*+('(&%!$+&)+')#"&#%&$)'""*&#%"&&&'*'!"#'&+%(!%#+%%$%()$!)''$*(&)(!)%!&#%(&*#'#*$(!#%!#$+*+#$!*)!!$)$"%+$""&%"+"*&#'%!)($+$"!#")##%&###&%)%#&'!!+)$&")+!%()$*(!#!&!)+"+'%+(++#+%(!+&$'))%&%"+)&)%&+!(#++)%%"*###$&+'$((&("(+"'"+$('*!'"$&$+%'%+!*!*!)'($'()*%&(*"%+*!*)#$'&#$!%%+$$'$$$
@r4610
CCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGNTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCATGGCTATCTATCGGCTTATTAGTACGTGAAACGCTTCTTNAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAA
+
.&%@2-CHBD&>.D;23!1">:<?,(?%7-=-/93:D%2D4EEF!E6!F$D/H&$"3-"=EF?0B6(*79+=:3A>9&D<!75.-@B'>.>;+7#.'F#,+1CG8=(.0F5%<=41@8@!B?2+G;#28(90H.'217.2'62770F@,H%!8AA,-#4*(;1D'25&34-*>DDG.5,$0*;D908C'13G+9:&.#:8)/%C'F,7-9'.$>;";((%<(/->1:6')?A6*"AC%8-==40B#;8
@r4611
NCNTGNTNTGCAAGCTNNCNAANGNGNCCANGGANTCAANNNCNNNAAACNTNNNTGNTNCTNANTTNGNNNNCCGNTNTGNNNGNNTGAGNGGANAAGCNCNGTGNNTTACNTNNAGTNANNNANNTGTTANTTCNTNNNAAANTNGGNTGTNCCNNGANGNNNCGNCCAGCNTAATNNTGNCNNACTNNNNNNNTTNNNNNNNCNNNAANANNCNTNGCTNNCNNNNTNTNACGTTCNNCGNTANTCTTGNTAGNTCNGTNTTCNNNANAGCNNNNNTNNNANNCTANNNNNGNCANNCNNCNGNCCNNCTNGCNCNNGTAGTANATTNGATCATNNCCAANGCNAT
+
#$"$!"##"$""#""#$#"!!###$#!!#$!#""#!!$$$!!"!!"!$!"$#"!!#$!"$#$#"!"$##$#"!#$!"$#$$$#"$""#!#!!$""#"$$#!$#$"$#"#$!##$$"$#"##!!"!!!$#$#$!""#$"$!##!!#"$!$!$!!$###""$"!#$!#$##!!"$#$!!#"""#!#!###!"!"$#"!#"!#""$#!#$$!#$!!!!$!#$""!"$#!#"##!"####$#$$$$###$#!"""$!$!##!####!##!#!!""$$$"!#!#!$"$$"!$$"!#"#!"!$$!!$!""!$##$!$"$"!$$!##!!$!"""!"!!!#"$$$!"!$"#!$$##!
@r4612
GTAAAGATTCGGAAGGGCAGCCAGCAACANGCCACCCTGCAATGGCATATTGCATGGTGTGCTNCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGNCGGCCTTGATANTCATATCNTCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATCCAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGNGAAGTTTGTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTANTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCTAATNATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCG
+
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
@r4613
GGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTNAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTGACATCGTGTTAGAAAACGNTAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTNAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTNCACAAATCTTTCCAC
+
<*'+)"5:"5#1H>;A"DAC9784=6$/4H6>),/:7<D<,&A$>'"7:H/)5931$*)&0=%)=!C:(75#?*&@.D>H".$/+A+G+8/#B;CF20?&A)C,<#%HE?%9BF<E@+0CF16H)<#92/.BH7F95/(%07/9,+;+<$E$.+2@?4#!:*(%5"=@.B6966/C1;%&,""?FCDBA7!?=0'711,-F@28;>,2--+@*@9B.+(@/#:>00.A%>63E:?+G9HH%=9&?8=6$8#@>'-=9+;#+"=8F24?$/+=BD<,B"F?1=2#G:A7F1@!D$:01.GC?:!%(%3+<">&$1GCD?8@G82'FC9,1#="2!H-$)6#.F!H'10A,1@<$2&H*(#A8,83B;A''7=C2>"*<)::597<!'+*$HC$8$;,GF-H(76;
@r4614
GATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAG
+
6%:$BC.10-'1D+4'69?F<7;%;:";;$+")"&?0#,0"<;8@:*0F.AG;:"/H0E97>99)*
@r4615
GCCATTTTTAAAGAAATATTCGATCAAGTGCNAAAAGATTTAGACNGTGAATTGTTTTATTCTGAACTAAAACGTCACANCGTCTCACATTATATTTACTNTCTAGCCACAGANAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAATAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGACAATCTTGCTAAAGCAGGTGTTTNCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCNTAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACNCCCGCAGAGNAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGNACCTGACTTACATTAATAAATATTAACAATATTAAATTTCAACTCATTGTTTAGGNTTTGTTTAATTTTCTACACATACGANTCTGCGAACTTGAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTNCTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAA
+
+)+&$$$&('&$+#!*'+'&)*#*)*('''(&#+'*')&&("!%(#)%!##""!'!#&)#"'""&"$#%"+!'++!(#"%'!&"*&!#)'"$!"&!+"%!+*(&*!$#&!"%""'$%'(%##*%"%(#%''(('%(+("(+!$&+#!$%$+'%#%$)#!*#'+)+)!)%"++'*"'+#+&'!%%&$!**&)++#$&$!("()+!*("*"$#)+%(()+$"$'+)'#+'$&&$*$%('!'(*+#!""$*+!)++&(#&&%'$!$$$!(&&+"%''"'''(&')%$)&+&$'$%"*"*!)!"))#"*&))(+++'&)!+!"%"*"(%+!(#&&)&+*%#*#+$*!(%")'(!#)""*&&('#)+&%(#$(('!)+!&$+##'"')(!)&$(("++!')+(#*)#%$!"()")(#)!"#!)#'*"&$)*+$!))'!"*'("(&+$*'*++(*!#"%$"%!*#'(%%*!%"')!&&)!#&))&*#&!%)+("#%"&&$'&#%'#%(+)!'"))+((")"%"&+")!*)()%!+'%#!)+'"!&(!)(""(*&($!*$%$&&%'"(%(#"%&&%"*)&&*!'''""'!"&(%%*##)$$$'"+!!''%#")+"'$!#(+##&#$"**&+(&)+(+%+#%%#$!(%*#(#!&*)*&%%(!$'++#+++##!*(*#*)&)&)!*&(*$*'%%#(&+&!*&&!"+(+%)!&+"+*%#&!$*&(!)$%*$'*')%)#+')#+("%!&&+"'%%$"#"#"**+#$"##%++***$
@r4616
GATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTT
+
A=,"%,G;%./-:=9@24,:27(,-"2+=%6%<2A2%0-78B=$@"ADDE'(;B%3&=0&)C>@)7B#&/H8'##3;E:''03$(B?1AA/(4"-;+%ED(#(H%>:#%1C<?<B;#G:,">$$5)DE4.5?AF
@r4617
GCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAAGTCACCACGGTGAACAATCCCCGCTGGCTCATNTTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCNATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATNTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCG
+
A>)%9AA4CA84B=H&/7158E@C03F?+G@DD>=11H=/(EE$HF4D0F9HC&=HDD>+64:!=:F/6,>F0$-C+6,A25+58H@B@F.+CDD@4.?'*60;H)@A99###;3'33B@BC@',7=$72*3),2A!$?DC*G7,E!F5=2379CBHD6')!$14-/52'+;=$D-*G<@B1(?+C&8E#!D-.G,8>02>,H%2?8/C-G><">,F+9B=C+&G*7?,B<85%0DEED!9--3;H+>@?$H$3.9;057>0)GC@=)6$?D0#H(%7;99)!B)(D9E2CHE94C
@r4618
AAGGTCATGTGNAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACANACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACG
+
4"H>-$9F2);9*D6G-,.7/*6C:*-@"12F<"*@:AH6;:=<'.HE&<+<D$</8#.-'%!1**=:0$;*:;:8>43#5?&)>;5C3#%*,E$(G=!4/5C*D:&1'AHC$DF>*;(/",7-H<?)?!,5'&1"<E=.,GA>A:5-E>G:-%7*#:.49&
@r4619
NACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTCGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCTNACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTCCAGCATCNCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGC
+
+C!")6C@#H:%0?-'/42#''(/:"C:+GA1',66?EDCD55<*:4!!:E!B6+C:E!;:7)$9,;#+6'/?*A26*-:+#>4%F'@$?&7:H<>.D8))#+79<D-(*2-6C,3>4B"E-#D7:A%%F22>*#F(:DD=8B1(/!&1-CG:8/+3?+E<B4!;04B4<&6D@C-A,>G.>>2F=E6$=G=/1,>!#EG@%:$21<2/8)73>E<+&+?*@8H":D9B==D69@!;1;,'DFD276?'G%E$*&9A*-/:/4*C34C,!B94B54(@F:DA@''"#.10#:G&5%<**3"+)-1A(>!32E9C;$-85GA-;15!D&C%@-8(7F
@r4620
GAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCNCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGNCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGC
+
G')=A'?;::@.71#B";@:0&0EGF;G#7)22156//@1*0F*!<.G)9#A?HE#,@$(<,719')/1AB@E3E;C#'."%"=%FC>98;/703%?6#09/2E<E=!0!*,..8-=@(='@&*21H9=<18)*,%B#65'E89DH,6=,,%1;27G/74!>@F:3$E"&1'H=9B&DF$A::E<@?><@/4DE"?+.>()G-3*630#1&58#284!4)9*,05CD?<0A+G((;=F&/1F656'/'ECC&9/;@!B5=")7&9)2>H$=)%HF>+135B8A:94A?;0E2"@#"!'-%EC3C"1&7A/))$<=%&F-:#B;8G;F<B-=@'3(EE1<3&"86.=>-"8A;-%6<,9*G=.C57(&'<+,02!+G)H9;54H8*7"E//C7>68(3@0,H,'<A;">A0C"&5?28"31>8,=F50,";?>G/$#B(*.<H.D.G:F-E/G2A8$%>B?8%'D,1,$-?,9*G1BC58)C5=0#$E>8C)7AG368B&;$-3@.'(<9H=,./3.:$+%)C'GE4A,"D=(D;675#>@:+99H@E@.)=*6@<6>>55'9E5*(D:5.#B,*9306,B(%BH#.(6!$-.!!?><>.8'>&(6H69C8&,)$?0<)>0+%+F=G'==-2"=BD.A>24AH)5F%*#-);.C@GFFF90$D:)5BD%3'CC%#?',3/B3!D)$$1*!==F&>;D').F&7!G5-:"5,:*,A!3D?(@$D58"/F9H;5F<
@r4621
CGAAAGCTCNCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGAAACAACTCACTAAACATAGCAATTCAGATCTCNCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTNCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCT
+
(''"""$#%"+))**&+'"*!))$!%+'%#'&'#('+##%"$&!$)*)$(#*++"&%**'+$&)('&+"!!!"%#($***!+''()&+'&+%*%$)*!&")')#$!)%)+!+(((&$$))$#!+'%*"%+(!*"(#("*&&&#!*#)+"!*"*&#%"*&+*'(!'++)('#"&*!&+**($"+*"+&*))*+"%%&)!)$)++$(')*&)!')'!+"*)++%&$%&)%&$)#+()$"&+"&)*+)#!"$
@r4622
TCANNAGTNCTGANNCAAGCCNCNANTTACTGCGNCGACGGCGAGCTGCTGCAC
+
#'*$"&*'"*%#(!"(%%&#)&%"*!&+&*)+(#+(*'!(%$+!*$#'+$!''&
@r4623
GTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTT
+
D,G#'3D%*26="1+H.<3'-7)&.7=23(DD>>5<=*7G>:0%2'"9E8>5H#>=0'/.D1*2&16@4'-1!>=9)AC?,:?>"*D6C7@8@*?",9'!'4(.
@r4624
GAACAACAACCCGCAACATCCGCTTTCNTAACCAAATGATTGAACAAATTANCATCGCTTTTGAGCAAAAAGGGNCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAATGAGAGNATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGNAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCANTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTA
+
25":+E3+0<4*4=;;A&5'GA*0$.8!>E<)49,&%1E7GGCG"E/>."A.?8EG0>86G+B.*?;%F7&;1BGF"!F)6%%#B(%!*<3H$FA!;'H$9#G8(5G*/-F9.:'%7,'F*&@)7*CB/B.$8'$C3=;&4&9!.2".6@($?1:FG@""DE)-$?GDE!-B.,<%5/1">:>@3%:C=:9B#"?(.&B+2;6;9E",)0*558!*=5FE?(B63E5>2@>F)6!"0:@8'*%9>"&HD>9A?9#8<)H-(<8097(01.4H%*";#GG%:)FG"#2$8:&A6<2@28>+9$:9*H@)'F$%?(!4%5H>D$1&!-A"*/E.#=)G'(<("C.7+-,5%+&D'1?)?A"<8##.27:0"'#F-)/.F)8@5F@G/C+%84=E;#9&AH=4D:$<?CD4'6F8H7A0!-9E:((3B
@r4625
AGGTAATGGNGTTATCACGNTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAAT
+
,9.*+#:#AC"8%54)7H!FG>;2@&)/B6)5"-;2&!.)-$-0=.;)-6$A;8<8>*:=@#<3$*$G"=!?5,HH<.35!<+(@%&-;5-'0/2?:2',%A#F.
@r4626
CAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTNAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGGTAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGCGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATA
+
19!B:7,7(EF18EE3!/("D=*)")4/0E(1:/A($C004$<?8F"$F/!H%E380;H(AC5D%#C8F461:H#6.*A:%0@.6EB%'+5;$!FA;<;D?0*HB(69'DB+$EDG+=-0/3,H3@A4B=F15FF<+:BC"%11#6$G1D!"3,4(&='=B?.(B906$EB#5<"-C2<24H)D6&)AH6&786*?5G.EE%!#6+,/.-!#D:8?+0F&72+&91"#G39$.#G5?*(*B"6C@C*>F=<*F(&5(D$GDA$.<$0$A??G(A#'-"G>(*@;63C;/>4D"(0!>(5#'G$6CDA8*E*2DGF"EG$1(.4(E>0HD:0:<6><.E9&A+6"96'';?:4>02-@!-H,'#5H<9"GD=6#B.C3&&'F4E80BAH:GB/%2;!6HE2B9D22A0B-4#!3@:7H.2'07?E)%FB1#HB+A'"A3>)1--#F373+DBCD
@r4627
TGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTC
+
>/*8./%:2"6A!3<>3F'2HG6/%#*.&!5*7.+=!'E:!02:H5;G@);G:*7;FD&C1F>?(>G&2(E;04@82&?0AB92<29:4#+)55"*G
@r4628
CTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTNTTCTATCGTATTGCGAGCATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTNTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCNGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCNTGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCAT
+
?*"H*)DB9%A<H;'8#2$D2!$>'E;2;+?%4B4$"C$>H!G&73/6<8<;"G*52.+8;A;67$?H<0.6EC;#D?G-9*B/+1)%E+E=/>,70!118#!HDFD05>%%4#,8;5?1!,F<2(%D)#A?&=+-A(7</?AD>()+'B@5?-0A/4>?0DH:AG&,+'2+H#><1A5D:$49''./@57@&8;G9DB&$3CB)0+2@=>C)+523$;2@+H"GG'</:!,)4;>@%6*DCF.<%:!-;H%&"F/5)0?*&GC971#?(C":C"E5F92A4(!6D?G'>7G39G(00*&47%H(8$)"5,@?.#/F9<GH++D
@r4629
GCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTG
+
-#C"A%09??)#!*+1:&F2%HEH#*#0-96:=*>-$G$77(9,),;E32(F#
@r4630
AAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGACATTAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTT
+
*++%6E51)8)70-8-,';H'8C>5#?.,78E7,0>B-:6,&!C9"?*:@@B;,:?&#&;3%08E9+#(E3<>B!?6.0,"*!0&;%$1057%4*1F#)>D":60&C6#EE2D&H2!-4C583:./:.;()2G*02>H@48>@/C!,6E-4*AEAA7>>E-++!56%4$D2@.,-1.EC;:%41,'=E>+BCD34EHC+6/!AE7
@r4631
GAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACNT
+
5F=9"<?.-%?*FD,D!%5C$<5)9D+G'?D6D6G#2.(8-?>=%6:
@r4632
GCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACA
+
B:,/43E5FB/64A$A&>7A0*'"0.&D34$"==?C'594BD7&B.:2<<2DH(&C8'D93A;9:-E5.?17)?5"8@4G!?0-2005
@r4633
CAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACATCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTT
+
;/',>2H*2'%5/'>5/ED&&E#10:545D699==;6=@C)2,;H3%8."3'.1%3*'.H7<1!7H1)4(&/AA#?<,AC!(;76H3+EC/<%A>#<6,FF0C42EC-8/C5@7@(@+6:96E'?7G60H3B+4;5H&(C9D0F9B$04#)G1C#4#3FB/<=H!>21)"/4"44>:*7(!$:6E@;!438('0*=1H&2'(==66',#"H@(6H?@A.+C;A"-?66/FG%C3DH:3(@4H7?H
@r4634
TGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTNCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTT
+
B:+:G3'*%6?A>D&($7':;?>8F'E7"<25GF2>185;.,)D5@;&G,:;CDH-&(14+=(A=7E3!8<>0+C7=@9&/5<A(?./F2G%E@FA@>8F33-"9%E7)G3'E/1,%%=9,&-&6G&ECCC=>/:3<#E;/+?,?B=B@@).9(88%#0,A.88D":/'*35.>+HD%C,C%61=#=1)6=-#*.6@CC%//95&?C1E5(#'":G?,,1,?;5G<!+$2F;(>%:4?;/FF>A$"#0G2$.EBC%,0*@#BF:*$9+0!7-DBB)'';!5/"/#F4F:51DF:2"G2/E*E$AGF4E"@D?E2"8%'C,FE8*E.
@r4635
ATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGNTAAAACACCTTAGTTCTCACCGAATNTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTNGCAGTACTACTGGGGAATGGG
+
:@H.@CH=7!%1CA-73)%G#2!):98;+1"="1@D*-6A3,060<2&!*%@>,&'44@(3+;0#'@=4C!(054'!?>D99"C:9=#08D$H08(5!"$G7C<2%>#E=D2'D2;9FB5A4%G;)"0<H,-D4(3/7/$4D#-9@,,3F06=>+*F97G-=F39)0B+$A>;E0*/#H)D<H;/B/!)@0)$H;$.55;1A9%/5A!0E/(DF)F8:*H,52&=$/90?
@r4636
GTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTGCT
+
?-,&9AA%:4!>B.!(0:)GCG.D76@'$6,@-/.G,D"8G7@(-D3;>-C+A%&@C!-+3#C-,#9,"C4FGD(F1=
@r4637
TCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCT
+
CD?HDC?0F8-/6$%#0G$BF*B65B&G9D;6>@G*?.F#;727B8+%/4E
@r4638
CTAATCANGNGGGAGCCACAGACCGCCGNTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGGCTACATCCGTGAGGTGAATGT
+
'%$!''*&*!*+!*#)#"!$"!('#$(*)$"++("%"*!'!+'&*(%#'!'&&()")(((")&("!!(!$(#&+*''%)*#+('+%!!)%$&!!)!)))*%#*)'(!"'%++%!'((#"$'%#'("+&+*+#$'!)'&#"("")'"!*)#!$)"*$*+
@r4639
CACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGNCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAANCGGAAGCAGAACGCGCCGACTGGCCAAGATTA
+
*-H.$"01G"0;GBDFB9C5'*FD0=,3)<08EG:=H3();&5)+D"+=(45:$622-"FDEE@G71:67($85C6D(&(5#5:(GH3-0B!:,22G%:978&5%)"/&1GA)@(#H=A51465&;#F.>&6$5GE$4!.)"6#5
@r4640
CCAAATATTTCGCATGACTCAGAACAAGAGCCGGTAACGAATCTTTTAGCTCGTACNATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGC
+
3FD!>-&</'@H;H8=G,2E#@&H8>#G><<FD8:534-<.27DA65-3*3E<>HH7E"-$@#.,76E0!<75#9<8+=%"F=)GC+#!0!;=;GH+6B2>0#0
@r4641
GAATCTTCATACNCGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACNCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCT
+
E4F?.,CBG>=1AC)%*802C7<$52@(1:E'9$6:>#/2.?7B;8:89-:E+9((2*@?F$!3$.+-E"+"@.2<.4G%@02-G#%+A73F5$0"(#1@/3:2.$5G,4F1'?)?E8/;7H1#*+>*(.9"%,E5,72!B7)C-,G19;'+79'2G$;B(728A84%B=CG>%H;=>&9C?(1(6(+#GB$)>8>B6>#7$&B&G$4-?.E)F69$*$(-=&E8)2&?A:B1H"/7*!;GH;?.:+=.+,)7/=2,-&%4@F'=,5)-60><GF&8C!<+?@H:6>437%($!@,.1@-$*&7:)5;C;(H56;0H$65@D(6-5G3&E'+>"0>$(ABD>F5;@8@:,!9,)!66/8;=&/B88G;E%7<!=$()+C,B37A>&H*4$3>F3;F426E
@r4642
ACGCATCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATGAACA
+
6+,*)$&<?0:83$)'=;:/@2#$F!HA6#6E3?6$1.&H8!@(!$8%-F3AGH,'2C:0.7.+2@>+=2@<4423&'5G
@r4643
ACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGT
+
'49,G-9A$=!4!/"9(9-:#5*+0H4HG@.>*7/0<#/F<-4$.E."@*68>4F:9F24&@.DD/F87BB'>61D%
@r4644
TTACGGCCAATGCTTCGTTTNGTANCACACACNCAAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACC
+
)BAH@&:AB<!;13>!;"+95H/);*'!8/H4+'28=(#,+E/B;,E"1B7?F2<G*=C?/.?+A2@%%..@D"5,FC30(%#%4!2AH/"3F1?'?/")(""'A=(D%*':/B*!6,G:#!A$@B4D-+:B.?D'')2!+(8F-&5,=B?%B9=+@47;
@r4645
GAACACATCTACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCNCGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGNCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCNTAGCGTCCTCACATTTCATAGGTAATGCCATAAGT
+
1=3*,EE'E<3;.G3D:(/*=%H$;;#(%"CH)-:G#0:$,?2"D:;.G<6(@&6*E)'="6F?9,A7227'@"!,',-3.C&6DB3139AHH4F>6(1/D:&&E>>6BF#-10'3,'B1&%"5;A<G"%3173D4#85A?'-@?7&E+E)099/5:3:F)%)F,2C":EG(':+@+8>?2%@G<"2!<6%>;&366C,A&4DE,#,--0'5H(+0E;#/3:!#$&9*=F++E71+HE18*"F29H:>#%$29;);(@<)+,2E$>-;E6%#6E.30,!)%)C96="G>,"3%H"*&##&3F18/3)/0$H8%.0,*7;F)"B&D!FH6D"0*'!+>4?7*:#=+H$%&+;#,H4=6#7@(F+%9"D6(()90H!*%66D?&.>G&<DB"5&B&
@r4646
CCAGGANGCAGTAGACGAAATCGNATCAAACCATAACCGCCATCGCTGGACTATC
+
##((%%!(+++('!"'+*&&#!(+))'!+&"+'&&%(+*)!&!+&%#*$++($*(
@r4647
ATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCNTCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTCTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCANGTTGCCTGCCCGCATTGCGGGGAGGAGCATTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGANAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTNGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCANCACCTGGGTGCAGATTGTCAAAGACTGGATAAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGNAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGA
+
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
@r4648
CAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGNCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCA
+
H;C'<)..D9?>E!,>#F@%))3"*/%6+#HA)9129H,;:#;HC;7E(-"FHH&B>+%A<51C$;!"F=%;GC!/)?-70C4#2=A+2*<'G%-%14)E!?%##H+D96%BH99=)1-.H)+!4<E6>;.7++*6;0'<4>7-<2GB988-47-
@r4649
ANCNGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATNAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATATACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCATTCGCGCAGCAAA
+
+#'%%+$$$((+$*('*+&'#!%%%+"#"%%'#'$(&%&#**'#$!%%*&$&#%)&*+&#!$'$"#)"%)+"&(+(*!+*+#$"+$($!+$!&(!%)#+"+"*%*#%*"$'&)&("!%&""(#&')'++&!""!#!'%$$'$!$#*%#+('$%)&+()#!)%#!("&+!(%(+"!'+!!%%"*!'&"*!%!(%%(*(&"*&#*"#'"+&)!'!+)%#'*$'$*$*%*"!'+"#($)+)
@r4650
TCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTNGCGGGTCAGTATGCTCCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCAT
+
8H+C?CDG3+@/@@7:!C;C?.'-<?)BG#2$)20@&D<H5%B941+6>.F;,"@@&6*:4-&><4G!G,"24,?,7<!+*1=@:>!$8<&9462465->GBG/$H3+5-,CGE=0!5397#&C;.!+G8?$6)?!:7?<8F&(D"?"'3><@*$H*DE*F@:B!<83908#(;5+=72#-"2.;<(E2%&F/=80,B;"0'#2$"A9E'4?@/F0<8D."2?B40-.CC0"%>=AC8FH@A@+4A3"<1*,..:60:::-,>+C+64)A5))+E(?<>6.+)41C7$-7(&+$EH*G2C8C9'/=8G'%E-2>=7@</#=7#::&'5?
@r4651
AGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGGGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTG
+
BBG9A%?"F@=204)H;?.,>>7E?.2E4?!2)@F)6,8!B20.G<?.(,.G119.?76$H'*@!AF1/3@8%%5>410(200?@CH/8E7:!<?H+;;18A$/>2><+#E0*#35G:*.209@6E'%F=1..G:/+85"#F.)#'&+),4-(0%46G+#'2--BD/'9>%:,'*G)
@r4652
GGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTNGCATCCTTGAATAGCCGACGCCTTTGCGTCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTAGCATGGCCATCTCTGCATCTTGNCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTANTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTNTTGTTTGTCGTTCTGGCTGAGTTCNTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATNACATCAGTACCGGAAAGAGAGTCAGAAGCCNTGGCCCGTGCTGAGTCGCTCATCATCGGGCTTTTTGGCGA
+
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
@r4653
NTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGANGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGNGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCANTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTG
+
4-#"+H80D7A+F-=H4>E8E6%(&AB"D"C;H:B4$63(./C@7#B66*;D-'3!0:@.C)9D">C+&&-368%&,8C&2"3,&??@$+>)B$$/DE$./.+#;2EH=*'=(&7!&H$%$,5;+,(HC#%%=!BB"HA)"#,9B-DD"7F"9(G7+'HH(.8-3"#!3A5->96B>7'#*793D.<E#7AFHC'&(<31F46?=-F60CC/B;G6"7=F9+G-F)40!3;9&)
@r4654
TGNCGATAAGGCGTTTCCATCCGTCACGTAATCTACGGGTGATTCGTTCAAGTAAANATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATC
+
)''+%)+%&%(%&""(**("#""&$!(&'*&#'*#)&%$$*&"$$(*$+$'$#%!#!''$""!"!*+%(')(%(!"*")%%!%)*'*")($#)"'$()!)&%*%*)''&"$'&$%*!$+'""+*"&)%+***'(+*"&!'&")'!)(##%!'(%#!&!&*$!(+""%!!*'&(')!*#"(&!)*)$"'+&$(+#)%%'%*'*
@r4655
CCTAAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACNACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGNCGCATTTGCTTCCTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCNGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCNGTGCGGCAC
+
5+<H,*-7-::H.6-C!,1.'0=@"&3,8?$EHE37%D(5=<$+E$71>,2F?B*35&%A.?7D-=EB!E(B03$:*194?,5C9;*53G@4=$1!"4,<)?91*&F9#8A"?HED=/)1?5-F:1-13:06%*:?5*$'.*!"!<21<5#AD/02B8$)6EF*4-527D)#+1(!>@GG>(<6BD0#<4B=5B'/.4"5096@E=(#2<A*FG":%275#08?.G6(E.=5A1336"<H$+13=2F,89H1C..+1E=43,$-?$1208$F$@../,=F:DE$4E/C,%:B*#!5=*)@#4:111@()$7F$H<F!DF4D.C8"DGA<04/4>;3)!8>/.3?+@*10/2).FF;)8(A+:7D6=C1BA5H,
@r4656
CATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGNTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCNCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGNAAAATGGAATTTCGCCGCAGCGGCCT
+
6*B"..FC?%*;'%E-!D9+%BA?#4./B7+(451/&>*D*"-5A@'0498<27?"5%EC$8D5-'<)/+2A.7,(,):H,45-A'8<&0-&()H-EH+9E*'/)H0D05*.))4&A7:55@%>01GF-B@2#%8)'G./<=1:2'*??)=01)3*$5DF?%0B9#61!!E8%.)?1*HE%00A-B(CF3<!%FEG#!1!1*H4=;$GG>A%AE/2;/,4*D/60?9;G)A"A$.)87E'*5"E1FA9<8B*B)1D73-9$4(.5#!+)!=,>."3C1%EF3+010/C<C#"GA+!4>1+717)/6.3/,,.'*!#)!@)&=5-#3%;!?F@=*,>.?>->5DA+):%)@))(
@r4657
GCGATCCGACGCATCTGCTCACGGTCAAAGTTAGCCATNTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGT
+
$9.G#(H;#*@.2-"3>'@/?EA79+DF1F.3;9)7#C$DG>*#,E'B%)#'09+$D/'7!>5%B*+C,+1!/5BE%755;31C0>.*#G#;3:%=
@r4658
NNGTGCCGANTGAAGTTCGCAGAATCGTATTTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAANTTTAATATTGTTAATATTTATTAATGTATGTCAGGTGCGATCAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATCGCATTATGCCAACGCCCNGGTGCTGACACGGAAGAAACCGGACG
+
&$&)*%%"$!*+#'+*')#%&'(##+)%#'(#(%'$#'%'()$!!()&!!&#'%+#&!")+")(""'"&+!"'&!'%+'*'''+'!%)$!(!'*'"$$)#&$)*#"$'$%('++%$#)'&#!)!"%!$#!"+"!&#'"&*+%)&*&*%)+#$%+&$%#!('"#)&'&#((*+!*%#&+'%''$+!%&&&%)!*!$+)'!&*$!'()+**+*%')""!!$)#$$#**'"'+)*(("#()"!%")!##%+#')$*$$)+%"(+#+"$+#%#&)
@r4659
AGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGATACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGNATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAANCCGCATACCAGGAAGGGCGCTGNGAAACACTGC
+
E#7.B5#9GF&(67(;,;E55/*:>?-+?%3+!H>4<;<E%FA@&'0"</5!9$4?>@)>@2.6F%(,DCE.7$)@6AC2&+:H25#:6,%:<F'7')=G$:&6.7C;?:B@$$<1;-FG?1$!;38,'919#8$B>(6E)',GC9;AE13+&1D8>A@2:7(;CE04D9.0C@H=>G+=7.9B,3AC4/8&C'6!>GAD!%ECDBH;,(D%!+#H=&#H,!33!,F45FE7%57=25G(*?*8+"E(50(6G:098";!A+2HC@986*H-.!=+DA.1*-%*#%8D!"G(=8D-;:F46F+5B53.4<E63+35420'"3$3&.$@=B+A5?(4H=*B*G>A4!#FD;917>(<@8A$<9H7(<1H,%D3*+61GD";)C08)$-3FD16"7
@r4660
ACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGACCAGCATCAGCGGGGTCATTGCANGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGCGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTGACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCG
+
#D25-BC/,H:&-=G67,2(/!H<$A$(",CB7196,&F01'#A<G5<1D)B'%3B,/<6B2HB+B$H/'<E?%A,,"H<H/@A=B27>>>%2>$A3@@*#E4@/?%4?=(F73-"@)8%;2);H!.+-HG6A.@A5@&G-2/*89!1"#F$!5DB(>2A?F)2A*0.:)-#BH:#-&0;F1!5A,"2C/C960&7!8$+F/5C$#:2@05-)6E*D$'71B!7.?-8"FG<578"%5&,=+:1,)"4@:/D#,22A3;*2.?D,,80HB@E&B<51C.C519H'<2!8,)=@%-
@r4661
TCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAAAATGAAGGATTATTTCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGGCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGCGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTG
+
.6%2&1;$H@F:<$E1!1A.-!!0>@18;@F<*$;5EG*:*);8'CB0D&=#"5#.4D8!>+B;"!)>:,HH14(4A93!D="/"C9(DH,$%<3B,?)=/*"B$1GC1*2><DA"'A&=H/;*!@EEC.72>=@H0%G9;C0$=%D#A-G>A38>='(7?)5#;$)&3*<#7":@4+;9@538C6#EB,$*2$)EC3<%BG1+$!D5=1C%+/@4%*G8,?(#,6H@?"0.9-$@"H-F3=0"%FB##894+!A(,587*-,CA#-D'2@103&)<5@GA'"'.*HH'A&%7-D0%$+'+;4"F)!>?&>=.8@:,=/A7,D007/$$022D#3)7!@(D)E+%'76"+'D=!AGE.7,B,/.AG@:"H,<'1%)4G3*6.#.(0C>D62HC5,F%H;E=</((::68CC*3!$0!"0F$:&+44<'#FG0@F"<2
@r4662
NATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAANGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGTTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTANGCAAAAACAACTGGAA
+
"A)*##%A43)D@@;>=G3?FC6<EE7?&8:=-H?*8+'56<)4&3>16'0'F-D,22/E4'8,"BF15:%H72($AGH9F.+G?3,,FG4H+#EFG:1@*!=@<&G76H6D5D!+!>+!-!-2A(E6+?!<C7E=/'/H'5%04!=0C>%#3%C6"?$0,:%34;2&;4"E9448D<7?9=/835>3<5C6$9?;7&744/72/F2/55@855*39>B+B>.!+HE%?)%#,)!)(!23A%B94CA:))?)89"56G)7*G3(:6#&;9/7,:,3*H0*<7E?D#7B>>B#)7?-(,6FG@;.&=*3(93F$F-#F$3D14F#A?(C>$.6-C6((48C?(?("0$'15E,$9'&5
@r4663
AGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATNAGACGCTGGAGTACAAACGCCAGCTGGCTNCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCNGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGTGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAATTTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGNATCGGCAGCGCCATTGGCGGGGCTGTTGGTGTCGGCGCATCGCGTCAGGCGGTACAGCCATTCGGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTAAGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGNGTCCGGGACGTTTGAGCAGAATAACCATGTG
+
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
@r4664
AGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTNCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCAT
+
H7;7;"6!5&#'$5'$@-!(<&"4"=47@.1:1+0:0*'6+#+>!'!A.?H?7B5":2"-(F*C*),A@=#;(,*..F=2=7:E1EBD"="=!6G+3!EE<<.(?@%*1G<*(?>!.4'(2/=9/A*&&&A,>=5).;AH(1.!//3%*A4:-+4?G082:A-*;@;B)56E>)(H#3=D<,BB%=0&<*!6.G3*CF8?F30$<@0-86?!4+8>'5%*G+/C-98!(=>$&&>4A&E0.=B*8:"89>EC58<@/2H0!B+*35#G%F(A$%$HB1((7%&>''*"/<+D;D@$,=')-&5):H-1CE99)F@8B>.;6(>.("2A&8$6>.?9A,."DG<##F0&=8#5.E8D%F23%
@r4665
ACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGNTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGNTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCNANCTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCNAGAATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAAAGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGT
+
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
@r4666
TATGGATGTGGCTTNGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCCCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTNTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGTACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTNAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCAC
+
06<E<C;;5#")>$+9BB%>*"A585A96>B!B4D!&".BG81F2!!#*E",BB<))#107'&;<+.7F=A,%HG$6)82=@+*833$#&5,.FG%,.;7@,>&!)G=,,B84/%:=&*2*AH.#&G*7=0(G,C>H8>GA49<,>.:"4/A)58(")B?E:/1>$2,=(E?D0-HG2+(+B33'8!/=28$+-?D%)/'*0>7(:,H+C.+#;;1@!/G4B4F)(,:EEEA3*5,':%;';<$>/2476A;8$1()2!F8)6(:DF1215H2,<@7B<"978&0!H.%E/EE/D>-!4FB/33>7$&C>95G")CA+')/1=4>=FC*#E!@%>
@r4667
CAANCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGNTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCNCTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCA
+
.3"7A+=")H;25A)E#:7C8<A+)C2-4;(;(A"#$'!AAE2@&=,;#9>'!'0>'.#27DF%FCAE5;F?!7G7=<4>!1"F,3B*,04>&HG-'3AG0H;651"E:.5*2F3=F!A2<H2-:9@8?,/F2>$G!?*8")-G485F@+0-(',$8'E/8?4B"&9C-,#+-+5A>-#38E9;B2F4'0C3AG8/'6,,B&7A,!0*!*0DFH;@1#A33@@<#3-8<D.;4<?%+*''&#8C:95AH&3)B(F2,%+:6+?2HG8B.1D"A-%'%7#&>7+$$A@)/!D:!1;9019<CA
@r4668
ACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCNCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCNCGGTGGTGANAGGGCAGNGCACCACGCTGACCGTGGCCTTCCAGC
+
05E3'2?;+;2HDH3EC&"&</"F"H0=3=9>F.3169>44F*=(9C@D'*3))A-6"D)1H-?32-/=#3%1D?)F">A*&66B-<.-@FC/F4:D;9*(;=!()$H3/0A=;41D01<(0D;,8/6C1<7A.6"(&70.F
@r4669
GNGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCTATATTCGAATTGAAGAACTGAAAGAACACNAAGCCGNCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGNCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCNGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGNCGAAGNCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCNACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCA
+
%!3#B99*H+B%7@%H3?C+'<BC@2FFE:/.@"G!5B)C19;E%>:7%9@HA"1&$?69(57)7;/6'-,&H4?47";$.@-A$;7"D#"+'9%7?$<0$E)#/8!'*730AB%1@B4D7A#"1:/,4=,/?0!-;20!A@+."3&3HB06+@7CA>'9@(":-)5/?-+F4$'D#-"35&*;H#G.@((271#*:(*?F1">)@/D#(:?$,.,,-5"(9>#1#&@*?.#',$@:E-D'@#5=F1G!9:A:>@!)7>8;>2:B0DG?@&D/4*:91=7-=.07<2"@A?E>&3(GG4%71E"9>6A4<08DE5@9?90(1B3-$2,>%#:+8(.B8(0.@H!7%1,=D)*H9.)C!,4H#&?4F7#,@?3422@E>F$?02(3>F38F.458:E)6,2CG,?.1@B-;-5788*4'H'1D)B6E4>24"!<37=*"8<&')GB8%92).-.6+C&6,&B';%5,#0#('4)=:+%D"&F$"HCH+D635'H/##:2H3E?0E3E"#B1<.-#,(:>A>65>A8$*<7<".74*-D+%-8#?-(;80.=F?C#*8/+++!9)"%&&:=G&BF>=*:C!A761F7AD$>&3FH#/)%)E>B=;.!)747?45$G+/(E*0665;DBA*&G/7./"G1HB=0=2,&3#'.$F.)AG0?B;%DFD25?!=?.&'/)1&HG*8>209G=/C@7*81<.3D-.+H*:'G4E;7=.2@B>H?DD?<B%&%,"F=<23:42!>)/%2,-G8(!F".B21"3EHC&@,3
@r4670
CAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCANTGTNTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTANCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCACGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAANAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGNCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATNGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTNTAAGCCCAG
+
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
@r4671
TTNTTNATTTGCNAANNANNATCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGANGAACGCTGCCCCTTTTTACGACG
+
*$#)*"#"*#*)"#%%)&$*!+%%*&"++'&%$!%$+&)*#++#((')($!'$'&$)+'')+%#)%'"#!)#*'!&*#***$(!*+#!#)*"%)(*#(
@r4672
TCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCNTGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATNCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTANAGTACCCATTATTNTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCNGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGG
+
*E/07="2HF8))H+1$BF(??GE&D1-2%/G/BC7C":!EB?<10DF?H1#6:G(&6($77AAB+(1C,*859.(=&$D*<38+>7A1$@=2DF-8;"8/:#4%*4:+-"8#'4?B66#B$"."/,<?:1",08'5$6&/=/>D!"64B+5:C?'9#.@*D<#23G&"H*4&<%$/!18.5%/'*2>#B(''5%F$7<$'336E!.2<4#')8>F.9*%<E"#."(%#*37E&")!?>/H<#1F'2'&;9#(0)$B@+C.=*A4)F)5#E,'9*D55'0;G1'('>80D.9#;,%E+<-3C:"@#.3#0>G.91>*C/B@?A?0<C2FD#6D8<F3FF3=&F1>;3H$)1C+$8!8@62CAC<+B>1%@0#B&5'.2$61/C'B/&->/*E6E*DD!DH@=5&>(HF&B87H9/F>G=/$4H348G5?B)C01,-1%A>(18),+4,:<>7B;.9#G+#(
@r4673
GTGAAAGTGTGGATGCAGCCCTGTTGCCNAACTTTACCCGTGGCAATGCCCGCGCAGACGATTTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCNGTGCCTTTTCNCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTNCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATNCCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGG
+
G6G*.&8991<70>9?HC0:GE8/=0.=B9C/(<6+-!'#E)3"#:H)';'9B)'E#.=B%=</&)A.E>F,,<3(+?+94*/3CG!BD6%:A9$!A,=@78A3)H),!7*H?:0?*6;/9?9=6!,1.F!,$209$8AB/%&>A!D0E3+39?F6=)F=,37<'C>#,A?2EDD)&A=B@3E->=*1.A7262CE#)E!):GG-"529A@@B#$B;%B;F8??))504$=2->H+58/45)<0#9+5!-GG02$&,'!/7?H2$8=G>,>('/1E0:;"',5E#%G%,35C%D/B!",D,61-.,@!;=1#>(F5>,3(;5H6!/8F>F!A-;,()2A/+;<)G!HG@46"'@,$<*EFAHG8"3#@@A%GG*,E>H65+#8BB729H!5,AF33(!&'+)F?4##1,/91'+6B/H&:F?B;*C*
@r4674
AAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGNGACGCTTCGGTATCGCTCTGCTGCTGCGCANTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTC
+
03A&(#1E6&6(.;%.G,FA*2AC;!3'"%*D*>(HB8&53G/$4$+E62;#G0-;$5"!3&3A/-A'#!**/G<05*.&4!*5++B&?#(+;5<;H@>BCEAE941"F7<D
@r4675
TGTTAAACNTGGNGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGNATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGNAGATCCGCAGAATCTGGCGGACCCGGCT
+
AH1$6B'9,:-2>;=0,?F($#!-%/"!(*%%>;3E&/4*:021358BD7::G3?C<$&9+>":>9E9CG'C4%A8A7&#(./=AE/19&FF8+>;"!30A:.@/,66;+/$9,$%*C*/E7>B:8H;H"!7$G/D@'!.024CD('@=7$DBA!":&7>.3@@8D&6D(AF*#E@
@r4676
AAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATG
+
%+C-51'B7<@*;)!$9H+68<4@F98?&(F5!DB-1#BG;+8%0)F%%F*5H:F%'):&F/0#;D!2;)E(A;'4:'HD02;$/<"0B2H<$H+$-.A7"F#8(*0'#9%:1/'*=*-,&3=1!6,.B>8A+6:/7D#A2>8$>,#9":-66?/H7@-+'&&5?H'-D@
@r4677
TTTGGTAGGTGAGAGATCTNAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTNTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAGTGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCT
+
?BD5#7!C/)42.:6#G?<$(4?178DH367#C<?'99%;#7;@8;HCD>(%)8):C*'E4)8F0=*4:1=H*<A(+<A"18065D3,+3%G;>4:?'943@9?;7C!-,A>$405DC?C6-.8'G1,623G6AC8:!F'G*+@D64,EA?E/-$/5C/40,(+'$F.H42*;6&BAF6&$@;7E8F$@<94%&'.2'7CH:B"FG98H5CF2<5433,*AA"<("F&+<&-,H98=+8A-'G**7,9*H4-+86..:!,2?A30:G3;?=<2<1E.$>./(:6A=-26G7#;E&@1E89G>6:94:)4,+2H"!="@+D')E8#0245%+6H)B8<7":10
@r4678
AACGTNCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACGCCAGGGAAGCCATNACCCCCACACTGTCCGTCAGCTCATAACNGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCNCGACAACGACGGCAATGTACCGGTTTCACTNGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACAGTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCANAAATCACCGCACCGTTCATCAGTACTTTCAGATTACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATC
+
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
@r4679
AGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGNGATCAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTA
+
A.$7'9H%%DB"*3EC,9+".680*E%B(*<*0'-%>?-(!??".H%F4G!-?4?$@8<$6D)=6$873A<0+1;A:=)**=F"#0B.(&2<!A<)@4C?$1";-4'G,30<B5'*F@-6>0$2/(1=@F';,$6'6H57CB>(">E395?&CD*3757FC,4=):C9@+9@=$:3
@r4680
TNNNACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGNATGTCGCCGGACTGGCTNCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACTCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGTCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAA
+
#(!"(++(!(")$%**#"'$""*((*&&+*(+!'%+#$**&&&##'+#%((+'!'#+*#*(%*#"+%&*+()&$+)*'($"&%)*&&!)'+'*&##$#'#**"%"%%*&)$#%!"$&+''"'#!#*&((#*+*+"#)(""!$"$!&($!)$#+"%)$('+#$(!&#**))%"*+!''%*"%%!%&"((#!#(+(''&%&#$!(+!&#*+&&$")#)+*+"&"*%(#'"+($"($#$$&&'((*$""'&$)&+%+*'*"'")'"+)!'")#&"+)#"*(&&!+()%)%(+!)&$#(%%&"#"*%%*#))$(!'#%)%&+%"&!#""+&"*+"**)(%)$)#"'%##(!%$*++(%&")'$#%$)+"#"&%)*#%(
@r4681
GACAAATGGCAGCGACGCACNCACTCCCTCTGGCGTCACCGGGCATGGCGCNCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATTGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGACCACACAGCTCCCGGCGTTTCGTCAGAAACNGAGCNNCCGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCCTATTGTTCCCAGAGNCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGNTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGNGGCGCAGATGCTGGCACCGAAAGCCAGGACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACNTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTNTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGGAGCGAAGGACAACCTGAAGTCCACGCANTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTCCGCCGGTGCTGGACANTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGTGTACGGAAGTGAAATATGACNCGCNGATCACCCGC
+
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
@r4682
AGNNAGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTT
+
(*"$!(&&+!(''(#)(*"$'"*+'!+)"*'"*("(*"%+%*(#(')%
@r4683
CGGTGGTGAAAGGGCAGAGCNCNACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTAATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATNCCGGTTGTATCCGGTAATNGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCNGCCCTGCAGCGCATNGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCNANCGGAAGTTTACTGCGGAAGACGCCATCAGAACCGGCGCNTTTCTGGTGGCGATGTNCCTGTGGCATAACCATNCGCAGAA
+
%+'+'&)$%$!$!()!%(*$#%*!('+($'&+%)%&!!)%%*%)#"#+#&"&++#"&+#*(*)+*!*"#(+%(*&(&*++#)"*'&%+(%&++%+%$"!+$#'$"%+$)++)&')"'*'*%&$%'%%$&)!+*!"'%#**!+++%+$&)%'+&)"'!'('(%!)*"*%$$)""(#(())#!+*#"%*&)%$+%&!)'$$(&*'&*+%!"+!%$+'!%+&"(($)&$*$*')%('%")*')$%&%*!#*!*+!#*()**!&*%(')#!#)%)*$'"'%%#')'*'$$&%++#!$$'%("%%$%%$#$%$+''#)'(+)+""%!)((!**!%()!!$#+!$$%#$%"&)+"%+(*)&%%(*%'*(+!%$$*"(!&%$#+#'#!**('+$))(%"!(&#()%#+#&#)$!$(#'$+!+&"!(()&)'&%#$"!%$$#$)*$(&"!*
@r4684
CCTCGGAGAAAGTCTATCTCTCACAAATTNCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTNATCCGTTCCCGTGACGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGANGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCANGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAAGATCATCGTGTTCGATCCGAAAGGCTGG
+
#(#+)(!+#&&'''"$(+$$'"*++'+&)'&+(')&"+#"*'!)(!*()$+('((+")#++!#)#+')+'$)"%*("#(*$*!'$#($%&)"$*()%(!((*#'"'+!)('(*"")+%#!"&))"+(#&(()*"!"%!"))%)&)*"(%$!&#(!$'#'&!&*)*#)%*)+(%&&$%%(!#%"&&*&"!(*)&#&!)%&*&*")'!*(""%!!%#%$!)%+'&+'+)+(&$$")$%!(*+*#*"#"($"'&"*"+%'#("&$'&$(*!&"#"**#$#'$&"!#)""(%%###&+*)")'(*%$#*'$*("')%%"**%!!)+"#%#&($#%%$'"%#$$(%*)($+))(*"(&")(+*+$'(+&(#$'!"&('**((%'('$*#"+"'&)"("!)%+*+&&("*''&*(&&*%()*%*%%#***'+*%+&#%&(&*!&%$#&"&$)*"+!"+&$'"*(#&))+!'!+)'''$%$&)"%'&!%&&"$(#%$&!(!+()!"!#!))*&"%&*'%
@r4685
GGTGNCTAGTTCGTTAANCTCGATAACGAAAAAGAAATTCTGGCTAAAGCNCTTGCCCATAANGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGANACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCAAACATTGATTCAGGTACAGGGAGAAGGCGNATGACACTCGAAAGCGTAGCTAAATTTCA
+
'+&<9178956H463"!;>1#09HA#E',?E'FC:B-:<*HF*5:-.AH?H1*5+#8#8,>D8?230F406A+G!-67?(=*>,.;)$AF*6"'C!-<=0%:F;)-&3)F.<G%,:19#DAG&=$%&-*!$,E%<$>*672(?F?/:B+F1G73D$C:2D&9?<*#+28-H#?F-2.$*%,%:*.%4"-,;B8G)3+6,5G*A'#*AE=A40:H=4E*A2,BE>"E7,A-2%>CFC(=9<,,<$)0BG+A)/D4C%/16<'0'H-+/6>4&AA*@GH5!C3>2;@3!-(67.7(GG$',5:C3+@E0E/&.%)75@"H'$7-3?B%2+E,5-A>/@!.@19;:<;4(3#$=B0E)?9!=(<(-GC80D4.!23&/-C')<@*&2%1,79"B",AB=:2
@r4686
AAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAA
+
#%0%:>C(7*G+..-;,75=G?=%&)+$&&A8G4A'9#*C6;=0
@r4687
TAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTG
+
A3$-G.")FG.10)!"#-35)##162!H*4:1+!B@&'*@$##8->8$6E4#44-91:?.8H68,:@3=":?G6"F#6F7</,FCH-'*"G(46A25G:+<4",E??12!0)E&D<&,.(EE%97$
@r4688
GTTTNTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCNAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATTTTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTAGAGNGAAATACAACCGACAGATGTA
+
/D&C%:A<8)5*>(<??>::9G"/(&A'D=;6)7!'G'+=:?9*"/5<-.G@!7G#<%3B6(B.E<#1E.A0C?<C.=;'+&+<>21<9)!E%H5(<0(A-64H64&"=H-<=71F#1,2!34<326,)9%%2$9"-<G&#A/F9%<)C)?!0"@GH2GDB<$2H"FAF$-%G.,5!+-(,>1.G("@=-;)4FD7"6,%;B'#D(,42960!@*F>3E#,,3C%.2,:*08<?G%.;!+D>5+0#:AC<=BC4)%H6@3@&"*!*7G*81''FA$'G2'B2,,<6!G4F8HD*,17!"=,!-*?%9,#6%5ED>+?B:B?AC/?!/(9@<'7BFCC*>2'&;932">(0&)BF:2&3,"73%6),19("-=</ED2<4B4(0A>E336G/$E0+@'$&@F/HG"
@r4689
GCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGT
+
/FGD-*6;,+/01/-D.)!!*.?9-21#C3"9#>2.9C5-2!GD5%4F0C3$%>H;&)%""+<$=7>8&#H%D6!9-6?+0!7%;;20&H@2,)21<,B%@@C?-+85#70(F#>;3.D3<.B&+-9-D8:6-16!.A69+FD;%H3B6%"5@",%%D:;$(CFEA$E?819,!#G-/D84).H8G*<+F9.6286)(G<20:)>&30F*"),EF>6(HG(7'5;&+'H*,D@B;(;>3FB-B*,=+&<$,9.$B'?1!@4"<C$73E)'-H>6E:@%/=?9#(>-=?<&@H0/84/2><3%0A*2HH;3'5->2BH9=#D-2?-7*1H67:<>7*A;$0@//F?B&*!"G+&?B
@r4690
TTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGNAGACAGGACTGCGCGGGNATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTG
+
1)85;*.H-,15@68?"9:B*(.4'@#,E!F?FD*76?,8%*,4>/)H<%/3$6C2#5$7H-22E=C%@#52%&"8FGA&$?=<("D/=&/(F6&=!FB5*'D3*.#5<!'+0GC;)%HBAB'*3C6@BG,820'D?@4(064-:%C:9*<+FGC-@%%(F".(#)"*!HB
@r4691
TANGAACGGGNAAGAAACCNGCAATACATCAAACGCCGCGACCAGGAGAACAAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGAAAAATCAAAANTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGCAGACGGAAANCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGNACTGCACTGGTGACCTGGAAGAGTTTCNGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCAN
+
#'#)+"&"+%&$!$!*(*"*$)(+%&*!!%##$&)%'*''"+$$#$#!*#(&+$''"(#&"!""&+!'"#%+!!+*)"(!#'(*##%+#&!$$+*%$&')+!))!#!#'+!"%'#$!&%+""$+%$&%%('%'%!!%+)+))'+%&#&&!"&"$''"%%!'')((""$+&!'#(**#)($)&$"#"($%+#&%*)'$%!')$$&&)($"#"%'$#((*($#%"!+)#")"$*****%$&*&')"##*)'%%#"##%&%)$*#$)%%*#"'!+##"&&)!(#"%*"$%!*(%'++*$'%+!%&+%(*))**+%"$"%(%#%!$('*+(!+$#"+"!+#$)$#()$!*&)&!*#*$#!*'#%'#"!&!!#&)*+$!#*'(+!%%+**(
@r4692
TAGCGCCAGCTTGGGCGATGNCTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCNGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTGCACTNGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCAGGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCG
+
345*FB1A0G$F&)9$798;@#+0A(.6B'AB%(&268B(&#D.,)/D00@;,+B#@9$GH,G$#$'-A;26&;>&09>9H"+2;>?G20%C("$7DD)+62F6?>*(.;8;.H')GH"@F;,3!%%+(F,F9.*,E/&7G=<DF*&@"6(!(+1&%?2@<:5',A&>)D5'*;':.#'@F0D=H";'$#47*)0F;BH6+4;H(D86%D9FA#!EB*%"0;#G?%7>(/(5%5,+=36A@05&A&?CC,>+(0;(29EH(,"6@(31=:E--7D>;-%H
@r4693
TGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGNGCCGGAGGACGCTNCCTGAGCTGACGATGCAGCCTGTNCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTAACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTNCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAGGACGACGCATCACCNCCGGCCGGGCATNATCCTCCGTCATGGCACAGAGAAAATNATTCAGCGTCCCCGGTTGTGAATCNTCATACACNGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACTTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCNGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGGCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCNCCCCACAAAAAATCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATNAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCANTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTNCTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATANCGTCCNCGCAGNCTCTCATNGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTAC
+
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
@r4694
GAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCGGNTCAGCAGGTGGAAGAGG
+
E%(4<"AC.*:+F$7D@?&0!4?#7G40/%1;>"1D(-6C?16"$,8#.$6*B9"
@r4695
CCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCCGCAGCTCCGTGCCGAGATGGGATTCGGTTAT
+
2(>+:#43?G;9%%2!9'B0E+A96D"E(9="<6)&<<DBB:2"6:*HG0<6,4%7@7.F#66.*@"')3*-H=0=GB1<=<"<1"7"00<!#
@r4696
GTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCTGCGNTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATNGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCT
+
!F,>'(0)7,19#E7A*"#/@<7B2C?&8,-%BF.>A,9!*H,+3(DE"-*5137(*!&@8231?>8(:@4-:H&*9.*F9+=E%#B-H$20H+>%;#C)6E/1A24%"+:;F'4:=<+(C>)1.F?C<F2(4*CG=&D?17D@1"*#3<+G)D@/FG<D)@5".=;%4@GC;+#H52E-6=#D&)4/*
@r4697
ANAACGNAAANNCTNNNGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCNACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCANCAAAAGCAGCAAGTTCATCATAACCCGNCACATCCACNGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCNGTGCTTTTTGCCATACCACNGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAANGGGGGTTTTCATAAAGTTCTCNGCANCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATANAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGNAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGNATGCGGATT
+
%&#%"'!##)!#!&!!%)+'%*!'&%)!!'&("$%!*'&#)$**%'+'*()$$$!)$&)*%&()$*%%!(#'#'(++!'""!&)$(%%(**&&'&&"!+##%+(((*!''('!**!()"(%""(+'!&()"*"!)!'$!(($$$&')+)'##+%###%"%(")#($)+&!%)*!'*"##!+'$#&#$'&"$"'&")&")&#&("!)#+!'"!()(+$*$$#"!!*&#*!((&!)!!)%%%#!!")%+$!#!&)&$#&$(%!#*&'%$#")'#(*)*+')&)*)#''&%*!&%&!)+#"*&%(*$%&&&!%!%%!**(''!('(*#%&!%%%"')())+$*&(*(*"(&($$'("#!")+"%+*(&)#'+'*&"&"&!")(($$&**'+$)##&(+!&++$'%&"))'$!%($!"'$&$+)!+'#*(#("#*"&!!+%##(%*##($%&'%#%!"*)#'$'+!('*++(!&*!!!+))$&)'&+"#(*(!'!"&#''%+"+('%'+!&%*+!"($%(#!""+)(#"!)#%!"$'+('!%%)"!)+("()+(##%**"&'"$)#'+&*+#$&'"")("*')'*
@r4698
CACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCNCTGNGGAGGAGTCCATGACGAAAGATGAACTGATNGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGC
+
)-H5G6-:70F3B9C&*8&E6+)H"!%/28#(+/;?C9)5BHE"6#?FG6-)GBAH(E@@9*E548!74E%/H,D@A..<#3*%6"7*<,4"DFD6.B28D#0A!>#'+#,DA33E4='+C8>(/<<+'D?9C0')%D;/+D580H&,?<"82!E<,?!G,@19"86:)BC!5&$F8<>03%12"=@=<,14+A=@:7?&<
@r4699
ACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACANCAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTNAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATGATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTNTGGTCATACGCCAGCAGTGAAACCACNCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATCGATTCAGGTACAGGGAGAAAGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATNGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCGAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGNGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGNATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCAACTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGG
+
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
@r4700
GTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGNTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGNGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCNTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACNGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGNCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCNGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACNGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCNGCGATGAAGCCGGGGCCTTGCAGGCGGCGAACGNGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAANATGGGCAC
+
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
@r4701
CACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTNGCGCTAAAGNACTGGCCTGGGGAA
+
=;>C#*?FEF938.,H>F-?C.3),77@<3-D64.9-5.E,4F"F101&,72C;#79(@@.(A#)"3-H9
@r4702
TGGTCATCAGACCCTTTCGTTGCGGCCTCGTNCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCT
+
+HG/F?5A83$1;F"13!&6%6H9/?#:EE,C!$08@&,3'=(9@B!&:;26"++6*68!/1248)&)6-
@r4703
GGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTNTTCAACAGTGATGAGGCATCGAGGCATCTCG
+
,"-==145B9'"F;#"21-(*(77")8D6@#;)2,A(H:'8DDD*35C%,4F1D(8:&>%D0605D"(0G;*F35;,$=C!0&/=)(F-1!:7:$"G>9;,="'&($0H*AGF4/066$AGEC<(9%$H.-)F/(01F8GBD#<&E1
@r4704
NCNGGGNTAAGGAAGCNCGCATTGCCTGGGGGAACTGCGACTGGATANGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGNGTACCTACGAGAAAGNGTGCGCAAAACGCGGTGACGACTATCANGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTT
+
%'"*'!#'&*%&*)&*!%%()*+**)%"&$"!!*"$)%)++"'+$(#))&&"'")*$%("&&)#%''(!#'!"($**(&%%#$)!+%*!)'!$&*'+"!&"+&)&"!("$"'+))!*$)(!!!*+!$&&'$(&&''!&(()*(!&)+#&$)%'"*$$'!((!$&'!')"$!)'!)**)'"!&!'#$')!"#())+*(&*#%""!#$')+!!"+&!(((!*%*)'&)&(##*'"*!)*#("(*"(+"$"
@r4705
TTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATGCTCGTTCTCCTGGTCGCGNCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTAC
+
/+&&)E@8AB<?>)5#+;568F7:"81E.@4-BHE;<&C:9@5."H,8$!@D/A?,'0,4H+8.4D;?E.>-'=A6,(2$@AH=8(A22'(:.7(9D9#(1;/#%F/(;))@60''-1E>$0*0G#+>(BB&,</
@r4706
GTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCNGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAANGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGANGCGTAATGTGTGTATTGCCNTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCNNGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTNAAGTGAAACCGGTACATTGCCGTCGTTGTCGGGCGGGNATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGNGGGGGTGATAGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGNACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTNCGTGGACGTTATGTGAGCGTGATGGCCGGANCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGNATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGACAGCGTCCGTCGCTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGNCTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACNGCCCGCCGGAACCGGTGGGCTTTNTTGTG
+
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
@r4707
AGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGTGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGACTGGTTACCAACCTGTATCANAACATGCGGGCCAATGCGCTTACTGATGCNGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACNGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGNCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTANCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGAGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATG
+
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
@r4708
TTACGNTGTNNCNNNNTNACNGNGTGTNNNAGTCACGNTGATCTANAGCGGNAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGAAGCCGGNCNGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCGCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAANTGTTTCAGCCACTGCTTNGCAGGCTNACGTTACTGACGTGATGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCNCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTT
+
#&))&"%(!!&)!%"&%"*"!"#*")(#"&'"*$&'$&##)'&($#&&#)*")$#&)+&$')%&(&'"(%#!%*(&*')"$%*%&&%$$*+%&'$$'$)&)$*"#+(#*&*$!*$%*!"!(*'*%#*'$%'++!*(#+''&%(!)*""#((#*$'*+$+!$"(&&(!%'*!#")%'$"$%&&$&)%!$+)*()#")+%$$*)(&*)("%+(&%)*'"*"&&##&!*%*)#'&&+')#)*)"+!$"!%%#&$'$%(%%+&#+''""''(&')'())'!*!$&"%"($**!"$!')%*)%(&#((*"'%+!&!)&+""((#'")+*%'(('#$**'!&!!)"))()*!(*"#'("('&+((+$$!"*'&"&'*)#*%"')(!!+""*!#&')"$"##($!()()!#)''+#!$$"#*)+)$(&%'*$&#$(+#%%&%''"'$*()"&((%(!"*))++#+!($#"())$"'
@r4709
CGTCGCTTTTTGCTGTCCCACAGTATTCTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAANATCCGGATTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCNGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTTGGGGATCA
+
@D8E,5/-DBF0#.0($9/*+HE03/%!,>,+A"*:*>)B-+&)D?A'-E@:)3<&=%5%@-66$93*E*,A'C,+.H2<>)5,5109>=;:#F>>D'3)9;.D&E%=1F8'4DC&>*/CF.,C2<B<'5>.A9?/$07<'A<B+CH8'$6G*;(#).!C-!8"'30$9>80,5)G6&%3<0&%6/#C)!73AB2)@'(/C1D>=0G"'3,G0H@';5D;'H3;F7F.@2#?-232"52&H?7E2BG%55&1=5F./%:$(.?=E2#AE"8*B;CGB$?E?;13F%%GD<B'!
@r4710
CCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGAT
+
D36622(7,#51&(CB+1*/C:9#@;'?:9&AH%65?<62FE8'"5.2BF$=A?+FB<'!2DB<$"GCG/D9>.')A.;0,#8C;
@r4711
GGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACANCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATNCTCTGTTACAGGTCACTAATACCATCTAAGTAGTNGATTCATAGTGACTGCATATGNTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAA
+
7C'C86$.50H(7<H.+:52E@FC:.,AH4*#H=D;.F5CB<$A1D05BE2G:5!08G#F70G,70"%91A/&2@<):/5$C6'F;C5'D7D90';C%G2.5B0+9H9A8E75-86HE/;<3BE9#/(8?%3G9?#!/DA7$B(G$!*$1!F>>%-B7!',..E37F>1,!F":3#B$-/:)D").(D1&('1@.:!-2.1)6&C)!B#!5A#.9,&+-*?<&<HC429$"C+',H13E"@1<@B&?>2$>AE8F9C.C#+7B:1;<21#4!B02G31992AEB+8B7%06".<7;'97G36;!B90)9!+B0.0:-E!F.+,$+-.A<'G063')*B>!.BGA;8)+>9=$(H+D5;H"%-:"/+3!BFB4(8C-!G*)2>E@2:,/E9#-86A:>"7#+2>#4D'<9A=:"+3!73'F(72H8G,1>+.A"
@r4712
CATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTNAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCNGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAA
+
(B';)6.8A-G!E$&;-,CH1;-'(*:H"?38!+:?,@&-;>.E/-(E#?=B?E!&5EF3$B973/.+8('#1?32"=/(;51<B>D:D<,E!GA:F+1/'B*D94#+=HC?F15A)2HE9/.<*:=+#3H$!.:4(!-$81DF:8$4!8B.<4"%1+&;)E(8A)0+2G>/BCC1D6>H-F:G@/,#5(1C;):@2;#9G'DEAF=EA93,<$(6%8A9B2))C6/4+(2!;)/;),?>(7#16'%>DG1%"4(E8E.A$0D%A57/H);9
@r4713
TCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACGACACCGCTGGCGTTCAGCGCGTAGGCTTNGATATCGTCGGTCGGGTCATACGTGGACTTGTNACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGG
+
A&6.!8E&7;$*4:(H@!73=0"+'&@6#31+>8E/:>,>)<"G?,2%1;,:#D8"#;82/'@,5)54:$04/*<DA!:/D/%'>5"9-D%+F>?:27D660A+!#,;>AE'(7)#'79B-"=EF,6/1*!!6$<!5>"'CB/;A470)GD:"/(F'-/)9?;A@0!"9G>*1D!54C4C%9*9;*76:(E2"':%06,0)8!,=%,3)2!=/E'&"1-EH.:5:>)
@r4714
TTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGGGGGCCATCATGAATGCGATGGGCAGCGACTACNTCCGTGAGGTGAATGTGGTGAAGTCTTCCCGTGTCGGTTATTCCAAAATG
+
<!'"86,-);6B*/82">=2$8>90$,),F4.9!F20!/CH9D:0+0!")9.0@4H3';FH02'A?*.,-01$?:0.)$E/EB*2?(:@&E'6H9<,E.;?1#.1G?-7*<>0G.#6$C.B2H<7%'%?C9*@B+EB5)FF80H+:30(1E"?+/E8).F1%:14E!5-?E34?=9%982-E;7':'=3*<4E&,AFG78
@r4715
CATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCNAATTTTAATACATAATGAATGATAATAATAATATTAANAATTTCCGGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTNCATTGACAGTTAAGCANTTAATTTTATCACCNCTAAAATATATCAGCATCTAGCATGCANCCTCTCAAAATGGAGAGTTTTATGACTAAAAAACCATTGGAAAGAAGACTTAANGATTTATCGCACTAGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCANACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTANAGGATATGACANTTGGTANAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCNTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCAC
+
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
@r4716
GNGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTATCGCACTTGATCGAATATTTCTTTAAAAATGGCNACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATNGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTNAAATCTTCATACAGATAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCNAGAGCATGGAGCGACANAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTGGTGTAAAAAATNTGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCNCTGGTGGTTGACTGATCAC
+
!!(&$($+$'*&)*!!!'(&%""&'"+$*)'$"!"&$!("&*$!+*%$')*+*(!&%*!%&$!'&'&(#$($#)(&%&)+&#&(!$!('#'(%%(&$'&**))(#&'#+$#("%+("&$)('&!"#'$%#)&()*(#&#''(+"+&$*%'!(!%"++'+("+!(+'#*+'$#)!("&+!&"%*%*%"&$!((%!*$+%%%&*%!$*(%(*(#))!*')&!!)"'%'+)%'+)+$'"%#$%$"($$)&(&"!+$#&)+#$*#$)""'))(+(&'$%**%!+)()+$%%(*"#'*!(!*#&&)(+'$%""&(&'*+)&&)#&!&'!#*)&&&!!&+$("!$%$'(!+*"$%&*$*!!'$&'&#)%($!#"'")))!'&++'+*(##&%'"!"(&*"#$*%*))&$!"+&#&%'&&"#"*%"***&)'!&%+*))#'"#$!$('$%**)!+!*($&+%(''!#)%#$)($'))#!+!+&"%&*()+&&""%#!!"&"#+!$*$'&+'+'+)#(%!!+"+"+!)$%*'*#(**"%#"%+#%*)"&+)$")"&$(!!++&(!"+!%"##*'"+"(&+*%&!$%#*"&'&#"
@r4717
ATTCCCNNNCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGCGCCTGTGTACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATANGGACAAGCNCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGCTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCAGCATCCGGATACAGGCCTCGNTTCCGG
+
*##%&'('+""("+(&!&%#+'+#$#%&)*(!!(%%')$+&!"*'"'))%%#*+#"%*#)$'&$%"))(!*(#%&&$$!*&+$$#!'%++!&("$'$%*!&%""%)&"("!+*%+(*'#''*+"'%"%)+"#'#$(&"&"'*%#+)&+'))+*$"$$*$!'*#%"#+$'')&%#'###""($)$)(+#&')('+(%%&*""*+"'$!"%(!")&'$%'+&'&)&*%&#)*)'#&"(+'*!)+'(&$)###&(%+!!""#%'+%)##$!)!++#+#'')%&+"%*!#&+!((('+"+)(#
@r4718
ANCTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTNGAAGCATACGGAAATCAAANAGAAGTAGCACGCAGACTGAAANGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAANATGCACGCCATNGTCAACGACGTNCTCATGGTTCATCGCGGATGGAGTGNAAGAGATNCGCTATTACGAAAAAATTGATGGCAGCAAATCCNAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGCTTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGNATGCCTGGAATTAATCACATTCCCCTGGTT
+
)!+%!$$)'$''!+&*)&)%$$*#+%'!%!&"%+#)"$!#(("($"+$)'$')$**(''""+!#%)%)!'&*!'$#"$'&&$&($&)!'#*$*(+$+#)!(&%!&$!&"+%*'#("&!)'""*)!#%!"!!'!+"*$)&+*&&)%())(+(+(+)'!"!)#"$!*()(*'*')$&()("'))$*#&")%'("$)"++&("&+#+"'*#+)$(&%)'"%*#")&!(*!%"("++%&$##($(*&(*#")%'"'#'($$)(+&!()%("+(#!!$#)+(!#%"$"%%(!#!*"#%'(%$""!$$$+$+"'"&*+'#&&*'+$!+$$("!)&#"'(%&+""*!!%'+(**(#+)*!(&!*'&$*%*)('&((''+%'##$+"++!%*!%)+)!('+"&&!#&%("#+$'+*('!&)#%&%()'+%($)(
@r4719
CGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGAT
+
>1EDA(F0H#<8&61+A'.G</'84?,>;9@6$HA78F!432&:D&?C<1!D3;"+=/.9?C<%H:=8519=<@#A&&4A+.&7>!GG3"""42#
@r4720
TTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGNTAACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGNGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGC
+
4%D57F>A?.&)!3(3$5%(!&1)?A:><C(E82+>$.#*G+>>0&(@#EF8B<=5>+%3%9<-'6B/!7D+"BD48C##0EG&>4,($=4H25<41'F/D&FG6)/>E$#75F9180=?!9"H(,B4'A+D@#223D@(*@8:#,&8'3+G4%-06".G02%CA946:!1G(+)%D(:+)"8'>*&E%C<**@6H7E6HH:?3=B2H;=!$;C,,%/05G@C?C("(;<>+36-;7#)$<,G
@r4721
GAAATCGGTACGGATNCCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACT
+
F()<?50:30DE&=7B,-C&HC@324C-6</%'A=&6$$:D>$C).F>:$088<)+)C",&HD<:9F+'%&-9*@/:'4FA2F5CB,3$-2
@r4722
TCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATNCTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGANAACCACCGAGCCTGATGTGGTTAAANGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTC
+
?@>#B*1%).1>5)@14<@>CE@$:E=C!!D83-$7"3'#>;3<DD(,H)=.!8)7D90'F?:@#"'D5",(D'G>?>E70.A/0G-:(77?',E&G4>7DB'H!BAGG1C>%,'"%(6D10>/5(..H8H=@2B"8E$59G0B68+*%%02F>'$G9=6%E2A-B&D&$B@?:D&,5!E((1A<0/2>>4E.&=F1CBA$3?E
@r4723
CAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAATCAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATNTCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGCNTCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATC
+
D8@F(H"G--2GF3A0"/#+$=?=D7G8C%570"EA"5G+?3D14E3<=#/0,-D7>&AE:HGF&<*/*&F3AG>@8<)2.6D#F=2.E59-:""D<1<G8'1)5*2+=$:*@&6&.>64@;1"%@,#&;(B7/;-0(4=6A$"B(A@$;2+:B<B;6:+>+"151B7AAD--H1$/*<;H!<8@$;(20/83(>4H':B+HE4)#@@"6(/;;B=3+G?,/69+B#A+6=);A3F)>)#<,3*/6-C,?19DAH<0+<9!4B60CC$G7D@'A:2*?%97=.2#DBH(=H)"*6>=+'4$7(?F?$;$488+?=AB";%(-->)=8;>:CB@>A<F*4<0CA4<1C4E@H%7F5"84(C6;.9;+.A5>/E;H-6>#,0<4;$?,#5976<)@1?=DB*0-165C+7(,>F?202B*+-3D7-C.>=?C&/9,&A=-$'+"1!!B+05&G+99@*6D5/#$$?G.3!!"82/+<*'%00,=8*1%1<)":>)@+HC$=
@r4724
CCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCNTCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGAATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGGGCCGTTCCACTTCTGATATTCCCCTCCCGGNGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCTTAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCNGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTNCACNCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTCACGGTGATGNTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAA
+
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
@r4725
NNTNGNGCNTNCTNCTNCGTNTNNNNATNNANNTCNANCNTAANTCNNNTGNNNGTNCNCANGANNNNGGANCNAGGNGCGCANNGAANANTNGANAGGNGANANNCNANANNGNNAANGCNGNNNGNACNNNNNNNANNTNNCNNGCTNAACNNCTGNNCNNCANANCTNNANNTGNNGGAGTNNATNNNANNTTNNATTAAANNNNACNNTNNNNNNNCGTGNANCTANNCANNNANNNNTCCCNGNCNGTTTNNNCTGTANNCNNGTAGNNGCNNNCAACNTTGNGNNAANAATTNGTNNNNNGNANANNATTAGNGANANNGGAGNNNNNTANCGNGNNNANNGNNNNNNNGGGNTTNNAGAGNCAGCANNNCGTNCCCNAACCNATNNTCAGACNNNTNTTCNTNNNNNNNNNNTTANTCTGGNGTTNNNCTNAATGCNTNCNNNTNNNNNANGNNTGNNNNNNGCCNCNCAANTNNTNGNCCCNCNCNCGTACANNTTGTAGNTCGNA
+
"!"!$"$$$!!$!$"#$#"$##!#"!#$!!#!#$#""!!#$$##!!#$"$#"$#"""$!!!"#"#!!####$###"""!$"!""#$##"$!$$!####$#$#!$!#!"!!!"##$"$!!!!!##$$$$"$#"!#!!#$$!#$""!""#"$$!!"!"!$"#$!#"$"!!#!!!""!$"!"##""$#"""#!""""""!"!$$"##!!#$$#$#$#!$$""$##$!"!!"$"!!"###!!"!"!$!$#!"!#$$"$!!$!##"$#!##$#!###"!$"$!!##$"#$!#!"!""$$""###"$"$###"""####"$"$!#$#$#"""#$!##"!!$!"$$!$"!!#!!"!!!"$"!""#"##!"!$##!!!"#$""!$#""!""$#"#""!#$!##!!$$!#$!"$!#!$$!!#""""$"$$"!###!#$""!!##$###""!##!"$!#!"!#$#!"!$!!$"!#$#"$""#!$!"#!"!"!$"!#$"#"$#$!"#!"$"!$$#$"#$!$$!!#
@r4726
TGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATNGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGNGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACNGTACTCCACATCCATGCTGTAACGCCCGGNTTCATCCGGATTCNCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGGCTGGCTTTCAGCTGAATGTTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGNCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGANCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGNCCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCACCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCNGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTNCCGGTTT
+
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
@r4727
ATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTATCTTTTTTTCATAAATTGCTTT
+
58@%G0!31$>D@E<E<.:-'7H*"A3'?=8+&,8B58$B63*?7>6)%72;6&;E3#66+G%0B7D--*3
@r4728
AACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCNCGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAA
+
32=FE*6=1A0!9(4#57721H:.'6:=>B&DB$4;&#@A:>$/G'0:4&3,&('4;.983A<AF02>8C9*/C*%?&(73%!/A:F+8D$.D98:F$E#.$'):0)G
@r4729
NTGCCACTTCCGTCAACCAGGCTNATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTC
+
#C*+>A379=+.?+F+*$&G<AE3.4:3CB*-(!3%;4=C0:2@H&@.!G7+/;(4::##%C8HE2&5EA)65%236946&=E&1.*,@)>A'*&G)*;*"+.=>.+G!*/&&//C*49G>G,9<&EG1*:*2-@?1HH8%=!()6G2(-7+/5(G<3)0*-%+68-(=,7@E'34:2BG)=
@r4730
GGACAGTCAGGGCAGCCACAGCCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGNTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACC
+
(96;:C41E#+&44<(9;E30?:*CG#&"7;553-/**G(EE=8@!199(');=C(HC0'#1<(:?9C/"/E&8)D?AB/");%456!(!$38B'3.F$'?9?(9;9E$HC7$>@?52)496$E#C0GB$+C)D!9G='23C@3>EH.)%":1.@B/2A<;"9%95%4C!.0#*<&#'A@*<A5G;E@81<1C4$9:="735=;3B0!>"+-'C%.,80-%@=<4C$-AD&.D:%;/%+&4>2H(DD6C(B/HH?1:,!1EB*'3-9$0/85>%+7+.)D48.<600&8(,@D@"$(:H7F+9(58=-H*8,399B-3,A1%EB"E30H)!<':1$
@r4731
GCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTNACACTGGTGTGTTCAGCAAATCGTTAACTGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCAT
+
;,1G>>@B2&E*G=BG(DB8)!-6?G&F&G>%?0A6(+>=*>4>AA:7H<)/>@3374=H,H).:",G<;!"=H(,&23.>-C<8'896049%6):<.2;;65$:618+&13&A;/&%C2-G:GG--1?!/&290=B;F,5"0$>3A+E/(>A*-B51!28&1(&.H,B517/>$?C<<=77H$6-0?(A=3<'$;",0#7;A94,(7
@r4732
TGATGCCGANAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATANTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAANACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATAGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATT
+
ED-GA/0CD>2:6:B*F74G9$4).<&/B=;1"E$.';9&;7-C@+>3&&$H:)5#9-/#.CH>!F6;&?!G@,7&&<?H39*(-8+:F76;8<$+$)&.,/;;3*E=68*-&:7/);1+88B<2@$0#==!F+%?(,=/%G7*>*3;8!EF+@1+9*(&C>1,,*/@5>88BH%0=3$;G(0D=$)0>E7)';64&@733$%.1>/H@-,80>15;4+82C(F:G08/;.C(4.6,82A=&$-D!?AB3$-.CB0+0:G=GBG+)73'@>>;/?&1%:*%81-(&!)()">A(0$/9D57;*(,F30$@??)(H#G$GE?E3:'!D</2A"@E:&*@9%H2-
@r4733
ACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCNGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCANAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCNCCG
+
5;6?%:A;0#(50+=&!9:"B%)(<+.13$.D'8--G4"%E4!+$0(E5+?*0+B72;)&4D6&H@=4E;+?EB*06&(/*(#5068&%#.;G--C>)H:+1#)+(&0E391821!#;1!%=?63@9-+6C#8-69E5G7H<F10A-E*=7'1CB<$C)<*9,B<
@r4734
ATCAGTTCACCACCTGTTGAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTNATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTTCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAG
+
)A975?<=&?,;-+1&@:882B9B!H6"<927<E!7A51.,..@3?>F=50!'A%D'H!39@15!":-:-8#A%73:"!6#/-C6=+"$C*!?1)(*?7F4<4(9')GD0CDCEE3$H/:GF36.3*7BA.67=&#FDC%H?E!:6G-2=<H*H-F0#=B<3B8?*F;!,'G4!9("2?6B$6?=5357C
@r4735
ACAAGGTNGCTNAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGCCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGNGTTTGNTGACCAGACCCGCCGCCAGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCTTTACTGGGATGNTCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGNANTATACCGAANAGGCGCAGAAGGCTTACGAA
+
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
@r4736
NAAAACAATAAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAATAAACCCA
+
#'(*$$&('!)&))!+"((%+!"&*#*$&##+*""')*%"')($$%$)"%#&&+")+
@r4737
TGACNANNGCNACGGTGAAAGTCACCAATGTGGGACGTCCGTAGATGGCAGAAGATCGCAGC
+
$(%&''$"%&%+)&($')&+$+'$!))%$%&*&+&%*)%&&)(%'&%%())#$#($(&"!"+
@r4738
GTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGANGAGNCCATCGTTCGCCGCGTGGTGACGTTACCTCCAAAAGCGCGCTNCAGTTTNCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGGGCAAAACGC
+
<:$2!2.!H!106H*%*;(/5-;#1$=($%$=7+E'5&<F!B)7=4A,0)5,@>@5'&((0"=*H""6G?(63=?002/0&8E92**A;*8-!A>A+0#)*:';;+#"D29%&:76-=@,!&/E"#;>1G(%"%*'<(<=!+@7%6%B.?04DE(.BF!&//G@!"$(A<?CA.BE;.=09C5'1859*#:3E>-E$>0>6-:'-2=<(0A)8604EB&B)>+2&,8,46:D4;+=*3B?*2D)0$@0>&F.<89'5==,?AD%@04GB*-1%/D7/*2">-05
@r4739
AAGGCCCACAGCTTCCGCTGTCTTCTCAGTNCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTNAATGTATGCAAATAAATGCATACACCATAGGTGTGG
+
&%$()+%+!&(+*+("!&%&)&+"&&"*'%)$$&'"&!$'#&$"&*#!'+#"'+$$)))$+%'))%*%"''*&$%#&'$(!%('$($(*&#)"'*#!$+((((!"(*%%#!&&&+&'#!("(&'$$*"(%)*&+!$)'$')'*(!#*#+&+&)&""%"%&$$%$)"&%&+&'"
@r4740
NTNNNTNNNTTTCGCNGNNNTNNNGNTTCACAANGTGTNNNANNNAANTNNTTNT
+
#!#!""##"##!!"$##!!!$!$$$"$#!#!"$!!$$$$!$!"#"#$"$!$$#!"
@r4741
NTTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGNGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAA
+
"H3(G&543"#HA='",3%(47!923F(.:9C'B%">)F!!5>!E0$2@6#$/)*F8"*B@!9,?C/4,4"?#57F>7C2C)%=CG'5*,1+476';4;,C2@%)!$)D-=345%>>F#>E#AC-'$F:;"!@&.2+<&,<'-*G7F?!#/4;-!8>!,;D,3-D;C1:F)B'&/,?,
@r4742
CCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAANAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCTCCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGAGCTATATTTTTTGTCTGTCCTATATCACCAC
+
EB?0C26=@3C%6#*6F,546.33;!-B%+*")2+4G8&-E#D)#$5(0,HA!$=0A?00?'-0>7?""$9!B-9:):*<.%27"2D$9.D.FDH#2F&-;+9';F%4$1E0(!-%+%):?/&7!D4G+@;(5.4-)77G2A;93-73G/%B+3.3@=D2C,"@D$7F87@,''D63-=,1-@8<+@;7C="'9;.61'%-F2FD9@/>(<&0-436B'EB(2#!&H560+8"".=FDD>+F<<'(#H1,C,*A'.D$*#(!#B
@r4743
ATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAACTCCGCAGGCCAGAATCAAAGTTAACCGAGGGGATTTGCCCGTAATCAAGCTACGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCC
+
DCA9;H#H!9/?45'2B%*&;@8G>HF">3B2-BH98%*>F)5*:?E+A;<3;4!H!$+'3F:G/>1C0/?08'%3%':&H/=0.80>)H,H1F#,"CEED9;!0C/34-;-*F",-,-91%4;-G$G7HE63C2"A6&0$&51,B1%4(FC0$>*E@,49+AFD=*C@..F12G*'HA3@>!&8?24BF?A<$
@r4744
NGACCAAGGATGAGAAATTCCCAGACCCTTTTTGCTCAAAAGCG
+
'(*$"'*$(+)**&$**!+"+$&"#!%"+&!#+'#+'"!($#$$
@r4745
GATGGTAGANATCAANAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGTACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTGAAATCAACAGGCGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCC
+
7C'-;:%4$(F.H5<<%7#'CC<%&:():8B%DAA$H.4C#$%,@$;65:@0+$+3!9/2#"D(&F!/+B&?H8<"H?+;&,A,GGF>+)@:9/$)8:,:67-=0520?D8F",/7;-8;F!5?1;:E,B>/-7'=*&)84;B,?"+5B>.,G*85GG(!.537D((&G3C&"="C*CA@<G&86G*$9D69,@?=5+>AC,=7?G0D0E":0-&65D&@63+<(?;?/
@r4746
CGTTCAGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCTATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTANCCGCCTGCTGCGCCAGCGCGTTCAGGCGCNCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTNGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTNCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGGGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTNTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGC
+
*1CD/+@<)-,F3BC(2G9='*=8,>"G0?$425C%=6'63$,"6++B,#!68FB:?$$,#/.1HC',;%;75D"<2=DE)GFE<'62/G(>1%47$6@7@%%*FH->4<A#!=6%8""5?!',$@5=F+C=H?G$5'A7/(A*0G<4-)F7;CFF20F6/H6'G<!4E#.+4?"!H9AHB<74&!=+"&3-*7,+.'##!:5G0>"@(,G,<3=.@=#A<C+>D-=/:;'2<C%G>;"36.!=H"!E5=;*!A?2482><%F:*0C-3E@;;G)6F@9$-H'&8G*."6F1!9#:&4>#,53='@82:G5?9%5E@>>F861%?C*@2"!:8#1"=.CG=>)C5=,$##D1%G'A4!%.<?;/9&9-*&,,HB$7=?:=D&%66<631&9?-,0EG/&$.AE%E-F=,;-0*/>3(E%29+3*6?*B7+6"?9:<(<0:&.*$?C+1@61!A%GEF)<&<CDH("G#)//G.#"@-->$=#$;G#$1)/.<:=A'?C1-555@#-&G/5/!;!./-$4EE,((4"21.)3*&H>H71&;<G"A?>#>7C*9*..40"$A0+6D"D/C8!.8C-'$!H"'*E/E>+02F3CH.<'6-(BFC9;C,D/1,7F:/=G9).-9&.(DC@,76BCE#@"6=D:F-"3B&#*)29B$7@$-3=A?D"!!E/;H0H,&=0$A$,#G"34&D,1F'C034FB197""D.)!>8#=
@r4747
TNGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGANGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTG
+
#'H$D2"1F1G6B)B#'8($C#(C$#&H<*$1).=,B0-EA0;!G0#E%-A*#D-,B$8FCB.90>715%!5FC@'#H=HC0E>*:?7*'7+72*=',%<=!(G28,C:1<457@+G6'=30;E)F?3>8@>/66.#B80=6+&A(0@1<F&>>7?$B2G5?97&69)<A26:>42,15A4(->
@r4748
CCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGNCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGC
+
H,6''6$A<28&/D*4<C<H#=?>3!381E&+9*1*C61!>&20%9)HB&B<9?,0>,9*EC!8!1"=4-C+*BBE;1?1@<36'=%#7?96/@A7(-A1>4*2/-2;(!HFB:>E#8,.=:B!7+C,"8>D7')708=!B?"8%/"7C("?C8@;:(<71C.2$''46.0-'!0*$9@11@2?>+C#F49:0D44+BBA>/G(:.D6F!2)*.12'F;E+@>'9!<)C:<F=H>!92<==.'A1(30G7$7>!="9F+=4'%.++"&)$+D"*9C5#4*@<:&B*"0FB!,:!(!42D2<2D8!9=,*1;-H"85*)':CCB2
@r4749
NGCCNANGTCTANGNGCGGATTCGCGTAAGGGTCACCGCTCCCCTTANAAACCCACANGGTGGTCNCGGCACCTTNCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTANTCATAGCCGCTGGCCACCATACTGGTGTTCAAATCTGANAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCC
+
!$"($&!)*(&!$%!%(#+)!%!!%+'##$"%)&#+)#!*!)&%*$$$'*&$+&*%+'$!"&*!!&%&*+++%&!'#%)**(&(+)*)#$!*!$!*#$!""'&"+!(#*#)+#&('%('"#'!')&($!$($$""!!!(&+*(*$!$#%(&#"($'*"%((**###'""!+!#"%$'#!+&*"%)"#!&!!)'#$$#"+"*!+$)$+!%("((!$%$')*&+&'&+%'%'"%&*&)+'*'""))!)$&"&"'$!$'&$*&)'"'"#!
@r4750
GTGGTGATGTNTTTTTCCGTCANCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCAATGTTTGNAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATNCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGNTCAGCAGAANGCTTTTT
+
";5$;2$><2%/#.%&91<")%@15&9!A9&:<280-F6GHBB>48@"?E56--=!@@1<0=.&,(G=+7!1BA-"GB<=!!CFC,4>%!.+)E.$+;$G5G35H2>+E3(G#)".7.#@D,D45A$(;7+;H=*05;5@A")&$/B&H&4'8386CB;-@3+"9E:5*D*&<'310=(*4-/G)#7)9H*D&0B,/*1640!%6>!2928<$H5D.A*H-*&:A)0&)<;$4?C-#"$&89,!GE(*('D*!E;<'963"=86)"("/)H7E>0:?83")H*=+G))'C%->B7HC8C4<<:"(4:-2B'6=)=F!''/B*A%C$&&?&F10EC7>,+
@r4751
NNTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCG
+
&#4.,*.>E-9$(DC0%2'B.DFED48/G)22/$:>+#G2F;@'-2$--1$1A.%CCA&1!F)H,(3D01*=8B6A!?F<B<%7$?!.AG2!6AGE#2B(+'5?H+E$E950$?H#G*1C0<;$':.<#$$$,B+>@3(%!G'3C6+162)3+',<AF**27#33!>"3((71781H+==26B59F"-$B1H@HG:",)E8?$'($=<:'=1.'7AA.#,A?D,(906H;0#@+<DE""5@4C/%C)#+A)162$0.EB))E<1;5,1*+3<2$996>EC'4>B74E=E:091!6F4"G&0/BH
@r4752
TATTGNCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATCCNGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTNCGTTCCGCTNCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGA
+
68"&.;(%/4>H%D*F3/$&'!@3?G&-B$295"(%>'C)8,-CC!C()A#"3G$G%AE7G22;9-4659B8?)7GCB7+1@"9.$HF$@8(=07!:#CG.)6G-@&D>*(8*63'9>0$B34)71BB1G%A!$D#>5E&($?;8:.119**!0?!?)3$%*.;/.86:6B'7?:*>C;-B9#+F//9GH)&8,+7;'H8+EC;G+.8;HC&G40,-&'6A<H:2:)'5;%(;7>:!><)%/57FB61'54@,F?23:0<'B1((&F@/AEE%9"#6+1G))<&#?::39/"4.9"!0/6:)@$<?0+?=:$*DG>7,19:F"1/%/&;3-8##;1:?*8GG8B(C4E$E*))+!,6(>$9EFCD>
@r4753
TGCGTGTGGATGAGGCTATCAATAAAACCTATANCCGCCGGAATGGTGCAGAAATGTCGATAT
+
&EA#1AHH+C2*'&G>C@$F+H&?3H2,?7:G4=:6&;%*$>#%3!,E5713!,/F(G1*52=
@r4754
CTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCNATTCAGCGAGAGANTAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCANTGAGCCTGTTNGTCTGCGCGACGTTCGCGGCNGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCG
+
0)D67">=6A3G=0+"@G#DF"3#8823G?:+,7:.;%.A11&F6(8=("GG5G6!<&?8H,;4$!A?*AG060E8,6)64'7B3F!$GB<>&86;6G=2'A,F1E*);9G-F$)16,E5A*'D,28+;=9:1):+?A3"G*?*F1$=--DF2C(2!H:"&5!6G6#@D.=3@D80F3.C!(H+:>$--4E)+G#)A#465"6>!281;*9FH!)1(7?@">24+D"%E7++
@r4755
GTGGCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGNACGCAGGAAAACTTCGATATGCAGCCCCGTGCCATGTATCGGTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAATACGGCTGCACNGAGTTCAATATGTTTCATCGCTTNATTGCCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCANGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCANCACATCAATGGGGTAACNGTTTTTCCCAGCCACACGCTGCATGACATGCCNCGGGCCATTTTTCAGTTGC
+
?*(,096!&:=BB6#;?G%%.%!B%/'5B05(>25/)G?G>FC1?#@.)1'DF++<A*?)E327?6#>!A-A2'46#7/0-6'A2#:=#H&;'-)'"0.3G:E'.>7F2+7)CF-D=GCC>*#)$:;H8;;'H.8(D1=5)%?5?":E"'FD/;$(.4@'1$@19D*2G!B0#902(#4<7/&@;CF*5:C;F"G+*27G+75%-)91-&2*0FG,#,H7F-E'(8)#"4:);%61!E!9"@#H=:6@H@*00536)',-/7=)CG3$;+4&*0(D2EB+HF-(=(H1*-@HGB@4!<+,;E!<#AG3!/?"G1#47?$6&%C?0(++9/C)4$D":15H<&;EFA#*;.:*;G,=)/750:H$3!9&A"&,E2F:#7D;9?C-@CCH@7?#4):/)',=1)3E-@E9)5$FHB#2GB+G8G!=7!!1"'@;8<HC:6G?8-"(!8-D7*3,DB)5,6'69$,$2A083%BC,88(8D
@r4756
ACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTNTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTTCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGA
+
;6;6>!6<:59D$<ECE9A.H><./@9AD-7FD92A=!:E-GAH)(<$09(G!D#C&1.!>!B<0;7B@/:<C,C0&B"!$==@%G9A!$)*+.:1&*F.5G9303A>:<HA-/&:4><@:,%3%4H)+(0H?B,@<A(/H/'@E<GG,>C-22,4"1+HDH8'A.CH0FE,'?,<B&D1?:$7$9>$=>@?7H##>)3796/7
@r4757
NTCNGTGNANAGANNAANCAGCATACTGATGCACTTCACGCCACNCGGGATGAATCAGTGGCATTTGTGCTGNCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGNCAGAATGCAATAACGGGAGGCGCTGTGGCTGATNTCGATAA
+
!*(!'"(!(!&*"$*%)#*'+#$*!#'"$+%*%"!(!)+*$'%("!(&*"*!%##&'*%+)$("!*!'(!)(+*$'#*"+%$&)!%"&$!%'')"))&)*%!#"+#&)&$+'()%#)!*%"(*)#+$&&!*!$)(#$&(*!%+')+('$)&)&+$$$')%&*'*))+&+'!')+"
@r4758
NCNGNNCGTNATCGGTGCTCATGCCCATTCTTTCAGTNTTGGTTCANACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCA
+
(('"$$#!*!*&+&"')'"#$!'+&!'*'(*%)!&+$'('#'"%)()&$*('))%#*#"%")"!'%((*"#+('$!#%(#(#"*#!%(")*(*"++(*+##!))&("&##'#)$%"+!#*%!$*')"**)&'%
@r4759
CTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAG
+
AH(4BB6)$;8A%$5+92%4G?#$.)3GE4?'*=C./6C*A:/-9@,5EEG4=H)3B83$;65C*F
@r4760
TGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCANTTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCTGATCTGCAGCATCTTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGNAAC
+
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
@r4761
TCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCNGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGNGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCACGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCAC
+
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
@r4762
GTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATNAGTTCCGGCCANCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTC
+
7;(3;!>79+9D'-G7?.GADE23;($;B*"HAG>7H0=%4F%'$2%#,.7"0>D!1,=C%HB$C&F/(#4C4>;/7:$=.*63"90GD*,%7"'985&B<,)C2,F,@40"8$14H:#E9B5FB
@r4763
NTTCACNCCCNTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAG
+
!**$%%"$#%"+((($)'%$)$!%%'$!*%$%%$)%"($&'#"#+%&%#&$**+"+$%(**%&'%+*)+")'*(")'%%'%#!%&!$$+"'")+!!'"*$+
@r4764
GCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGNTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTNGTTTTTTCATGACTTCNCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATCCCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGNCAGACCNTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGNAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCNCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACNGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGNCTCGCTTCCGGCAATACTCGTAAACCA
+
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
@r4765
GTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGTACCGCNAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAAGGAACGAGGCGCGCTCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCNCT
+
-?<!C*"A33!=G;7F988AB&HF2$(:5(G49#5,1F@H>E-D)3:A:;(D4%=0"EC;&00*ED!785GDH#-;$(C1E<)H@H0G(:=D650A"!<(/"25*30<#26F3G"2=9A8&7@E#1*5/>H11H$A5E$46<;*9#.2:D1G/.>H(,!GD"5;!2;#C:,<9!.H%C!E?,,3"3:1D1375%*4C#'(&99'@6'"'"$G.H.-9A(%=DD:'5:)$:=*7GB@H!>@%2A9<7A$E:%*%864D5>1*<"9:')5>F(E$#&&(B=-8;H#+)02+##C3-!<H=E:6E!HF<
@r4766
GCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACNGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCATAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGACGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGNGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGATCACCGTTAANGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCC
+
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
@r4767
NNATCCCTCAACTNTTGCTTANNACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATAGCCAGGCTTAAATGAGTCGGTGTGNATCCCATCAGCGTTACCGTTTCGCGGTGCTNCTTCAGTACGCTACGGCAACTGTCATCG
+
"#%*&($(%()(*#(%(#)#(#"*+*(!$(&&"%'+&&$%)%&#'(!*&"$+)$(+#$*&$!$#$#*%#)"&#'+#!"#"()"+%(!!''&)")&$'+$)*+!&*"#($!'"%%#(%+'#+&(%'!&'*$%$)$*""*+($)"*!'%+#"$$$"'$#$+%*$+&*#$&+*##%$!"&$#!#!'))%)'')&**"++)#!'(("(#'))'#%*
@r4768
ACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGNGATGGTCATACCAATGACCG
+
)*#+%&&**%%"+"*+(&+*$&&!$&$$(!$(%!)"#!$(%"!$!()+*"#%$&"%'*$$+'%+"$#"*(+#"*#"##*!*+%!'!)#)(*
@r4769
AGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCCCCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGNAAAACCACCTCTCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTACAACCCGCAGACGCTGCAATACAGCGGTATCTGGGACGGAACGTTTAAA
+
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
@r4770
GCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGNCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTG
+
-C'>93$&..)8/$)===--#(DE2;("74(>H99&+265&-31"1$3.3&(%;&/A4>F0),7H>%@E@2:3&4-@*"$&?+$&.-'"00&B&/6AH*9B/-%,8?E&A573E<".4+:146?FB5:&2C1?$H%:F=<5/6%"F54)#)G7BE+2C0'A-B<1*F3)334</9!.>2H@3.4<*"1,>9+*;?"C"G*$;1!!/@%>"4;*E'$(!9/)1(B<A3""E=C@?$2G+1H6B=,-?%!H*,*EEFHD:0=DCHG4?@)8->H?4,4/!?D"#BH(.';9EH,;3763#0"G1-;#/1(&H0);.1==!,&3$!?$%E#D2'?F!.%%#=-(*!F!-&-E#73724:/B8:=/4@:?;F-/7?!2E<1@"7')G@A8B
@r4771
GGCTGGAAGAGGCCATNGTTCGCCGCGTGGTGNCGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGGTAGGCTCCGGTCGTATGGCCATCGATGGTCTG
+
)?,)D9'D%E6,=80&>:G%@-%$!!."'54.E&:!3./8C@'6%G,%8.*1#+:E#*(=H5"28$(7:GD85:%7=93:4'*4>@H+#>/(,'F!A(>@C*/!>+B>86C!A.B*()*8.GA5:CB!#E'
@r4772
GTAGTGACGCGCCCAGCTCTGAGCCTCAANACGATCCTGAATGTAATAAGCGTTAATGGCTNAACTCCTGAAATAGCTGTGAAAATATCGCCCGCNAAATGCTGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGA
+
?9=*:F+&+"-B/=1+16-8A13@A1(>5<$H14&.D+E,@3")C?.2H,5@(7-,E(,'56=';'-FC7%G/@29<99$)@;F*)C('#0DD:*;(H)**9F<;$43A5':GB66%F5@3&-$1.1C@<!9E?7;@47"72$45/>+6="><:-,6+C?42G8#D)71=E)?@$DC<G5A;(F*,+%?H*2><9#3*-/;G<08;@$4*--GA":F4*48**%'5*")D3G-"#
@r4773
ATCACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTNACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGAT
+
,<2B>,&1F'B9#8H'(4;.'6%0)%$>C&/AAB8%38.<2.)&'>&,6A<2$*9#:GC:9D+B0/<-E!)(D2A%4:F'C:G.*.))#-);83''$=)#2G">8AB9,/64B:<G(/2:F<HE&D;A5AD,-0:FG&:$2:=<#%+8%+
@r4774
GCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTAT
+
E427/'63.8;+@-20'9&);$&@27DF6B37)=8?HH-A/9,-E$DF4!9&@:D&,;2/+%;E=C9#D$8=G29E6*,:'$3
@r4775
NGTCNCCGGGNNTANAGGNGNAACCGGCAATGGCGNCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCANGCAGAGTCTCCTGNAACTGCGCCGTTAACCCGGACGT
+
*'&"&$(&*!%!(%!*%!!)!($$*''+(*"$*'"$#!#%+(*'"')*'+)(#"*%!*%)'%###())!##('!)*')*!+#")$#'&!%!#+!'"%'%"(&#"((+'!((***$%#!*'(#'!!*%'&)!*"!*!*$")(')"#)*(%$#!%(
@r4776
AGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGNTTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAG
+
465+4/1-D$F"-,E"(+.E'B>50"6&*"'FGF(+#6$H%?G4@*5-HF=3A"9(2=0F=@-,H&$172H<#A,E;G+1C9)0@E()6@0*>$9>9F%/7=E1>%F@7=.<@!6:#>"-'FCH!;H"0?8<).D?)H"=0G?;@9@%9%,9+)>1?B.2+"4*8HC5GC*)A@36$30>31>4/FD"%<.8/.9)G9!-743?G;06&%-9!?'#?%(-0;?A)03*(::A=8"3,,A%B:')G:)0E;(B20-0*&#",6?$C!4B9/)4=G.4,-5#B2<3GF#)50/GCE'6G42/72A>!G*&=D(7D"7A8*!9<@;*GE+GB=%FC$!'"*<A4">#1&A:'F<30#:)8&1$A&.4*<
@r4777
TGTCANANCGGCTGCCACACAGGCAGAGACNCGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAANTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTNAGCACATTTTCCCGGCTGAGAGGGG
+
((&'"('+*#%%(#""+&+'$"%*")'+'%$*$*%*)'"(#)%#'!'%"%(+%*##"!("+&"#+!+"&""!#*"'*+))#!#)&(("#+"%'+*"'#$)&&"*$%#!&"*""$#%#)"""!%$"!!%!))+&%+"&%('%!%*'$*#(%#"(*()""$((&$"$%)+++"**!%$%##)$!)"!&#(&)"'!&*!$(''&'#*&!#$('+$+$((+$
@r4778
AGAATAACCCGGCCTCAGCGCCGGGTTTNCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAA
+
E#"(C:3"8%C+*HE%(1.@5;6;';,12"/98%-"=95%3E=A/H0HE%AGF9737%<1&37&2@,<C3D:AE:?=&=-<3+%&5
@r4779
ATTCATAAGTTCCGCTGTGTGCCGCNTCTCACCGGNCGGCGCTTTGAGCACGGTGTGACGGACTGTAACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGNTGCCGGACTTTCATCGTGAGGATGACTGGTGGCGCNGCGGCCAGAATCTCTATCTGGATAATCTNGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCNCTGGCGTCACCGGGCATG
+
-?<)?7FF&+@,!8>(4>C$CD5*&=DH!)!1'2E:&*9/AGD.5:)&+*1>A+H6"92-.;B&8?4?7F#AC-05A*G?;'E0?&!(@#%?B820E#-A;GD*58D,(<-.=?BG27):C1E5<52-'-E%(35(,/"BB<48D8A7C0AAD<-'7<F'*'(A7C,&4$"7./@A.+?.6,!0F+,!(3D9/,D4=5%7'>(974,8:%?+,1:26!-?C2#233+>C<88(<@0=4-.F2A$*A,8>=,&(.1:E(?-F#C,A?F"F5<6.;,/3&=-+"3#7?%1"<<->3G;&2??F8<"D2,7E04G7H";'.;+,=H&8GB.()8-/689@(:(GA-@F6ED9$"CE;G-G2H9H'1'C'+@FC>',B*B;E(C!$;-11
@r4780
AAANTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTTCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTNTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTACANCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTNATAATCCTTTTTCGCCGCCGCCATNAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGGCGGGCGGTATATTGCNCCAGCGGCGTCAGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCNCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACANGGCTTTGAATGCCCGNGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCNTGTTCTCTTTCAGGCGGCGGGTCTGNTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGTGNCATCGCCGTCAGCC
+
%$%"+($'#!!#)!**!''+")($$$"$&'$)$#+)""%$!%+'(()#"!)*"#%"""&*%%$$)"&)%*&#'%&'!(##%%)$*'$%%%!%$*"!+#(&'$#%)%!#$##*(!())!*!))$'&#+"'$#"'%$'*(%!#*'*!('&+$+("$''"*)$$"&+&!%+)*&"$"''$#"!%!+)'(%!&##$'%$!'')&%+"!%*$#%!#+%#*$")(!(*'!(++%%)&$%##(#%('!#%+*("'+#$(""'%%+*!"&+'')%$)&+#"*#'&**#(%**!#%')!"++")$&)")*'+*$)!)"'&+&&+%#&(%&&%$#%#+&#+&(#+!($%!&+&%%)($+(%'*!&$'$!$"!%'()!!'+*&!'"+')()%*#'""##(&$!'#$*')#(*($$'($+!**!*)'!"!))#'*"!'%+%+$'+%"#&*%"!+$*"&**)')*#!+'#"+"(!##(*"$*#')(!(%"&$"$(""*"(%%#+!*$)&&&*+%"')$('+#%+"(*"*"*(%$'"#)$&!"$"+*&"!"*)%+!%'!!"')$)!**)#($*")'*)$!"+#!$"%)#$!''&$!))%'*!"$+($+'$+"!#&"+'!'*&())"!(#!()(!*#$(!+(&!'&%#%"!)#%""*$*%!%%")%(&$)"!)'#$"(%+!"!*+'&#&#&(+$'+&**)!$$''%%!%*##%'$(##$(%!*')&)("!$%'&%'+#($*')#)#""**$&+'&*$'"'*!#'!%#(&!$*&+!+'#+'!*$(#&&"!"#)(*%*)$%!$+$#"*#&)#$!'##+$(("%)%#%$**'!"*""(&"(#!*(*%+"+#"$%+%")#'!")")!#(%&%")$&+%')#&***&'#&$&"&&)!#%)'+'$'+%)&""))+&#(#&*"*%$!+"$!#!%**&"+*())*&"!"&')'(++#%'+)'&'%)#())!'&(*!*))%")#%'*(!''!"%*$$')&))"%*%+(*+
@r4781
TTGTGATATGCCGCAGAAACGTTGTATGAAATAACNTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCANTTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGANATTTCTAAAGTCGGTTTTTTTTCTTCGNTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGNTATCCAAATGANGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAAGATATTTATCTGCTTGATCTTCAAATG
+
8,#0858&0!D3<9,+D/C#.4"%!8(0@"$?5CC&'<<40.%'8?1F>+A5HA:GHG&%!,1)94@F<+B/)8!3,!B,:H>A@0'EF-E!B@!@/;!@@4=0=C3:A-)$?E;:2"/7%.&:)!1,2D:5%1*.F85)2";22,#!2(#4G;4>'25-/8,@>95CE%<E9"6>785HC%A?;4(5$1.C@2D'5:414E>13:'/+?>C,+?#7BF+#.B!5-%F@8$$=2#$1@()"-?'7:"F4E-(&D@:"?1D#($G,AE=(%8E$!<>4&0:,-4/#D1";%38(!1*,!%+'F6A-9($35(-++1!8B'=5!+!/2*>(>4,F-HE,,"<(>?6833>'.6)A4<4<821')#?.#A,$@%+$'%,=2/4;&5:&B6B8FE*7)=0;BB6%421D*F+F(9HHG3<E;.&@F+B:+</,G6@3,F&"?$=>(-%!"7,$A/1"3+<9#855949<(B
@r4782
NNNNTGGNNNGCNNNGCNATAGGGAAAANCCGCCCTGNGATNNNATGGCGCGTAGTTTGCATTATCGTTNTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATAGGTTGCGTAACAAAGTGCGGTCCTGCTGGAATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCNTTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGA
+
""%&*%('%"#*'"!*)%%('$%'#&*&#!($#'!"*&'&''"#*!+*'"%(%""*!%)*$*+'%&'!#$#(%#%+'!%+)*("&)*''&#"%%(+&+(%)!!*+"(!&#&)*$)*"$#(*%%)%&')$!*""+&+&&!)#)'$##$!%&"+"!&&!##!(("&*')'&++$)+*(&&$#%**#!#+*!&%&)"()+*(&!'$$!%#)+')"+($)("#&'$('##!*+#*&))!#)'*'&&&!($")$%!)"*%"'%"!#$)%$%!&"$#%'+###%&(&+#'"%!''&!*"(%#+'&#(#(*&$&$&&)+'+%$'%++"+(!"##"'#$'"$$**"%+#")+*!!%+$$&+"*')!'(**&&))*'*$%(++#"&(%&')'!%*&$+$'()"'%)#(**+%$%"(*)&'''!%&)#$(#%$$"#*'+"!"+*)$
@r4783
GTTTGTCTGCAAGACTCTATGAGAAGCAGATANGCGATAAGTTTGCTCAACATCTTCTCGGGCATCAATCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAG
+
+&&*$"#)$#&()*#''$%#&)'&&%#%#$(+"()&)'%**%(&$!&&)$#!"!)($$)$")(*'$#$'!!*'#($)%*&($%#!+&&(%$"&#+)#&!(#%('&$&("+'"*
@r4784
ATGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCGCGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCG
+
@3D:6;-?@-)+GE,H74HG<F7(63&1##:$9$6%=H&1)FG%B&4!9E;G&603%8E$$+,6?-9:F=.10?:3!A.8'F6GB:;8E@G>
@r4785
NCNCTCTCNCATNNCNGTGTCNGGNNNTNNGNNTCCANNCANGAGANNGAAANNNNCTNTANATNTGTNGACAANANAGCAGANCNNNNNANTNNTGTNANNNNCCNGNTGNNTNAANATNAAANAGANATTTGCCGACAAGNNCNTNANGNN
+
$!##$#"""$#!"!###"!!$$!$!$##$!!"$##$"#$$"$!$!$!!##$$"!$#"#!$$#$#"""$!"!""""#!#$$!"#""!!#"!!"!!!"!$$"$###"$#!"$#"!"$##!$$!##"#$$##"$$#!#$#""""!"#$"$!"!"#$
@r4786
TTNATAAANTTAAGGGTTACTATATGTTGGNGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAGTGTTTTATCTTACTGTCTTTGATGAGCATGGTGNAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGCAAGCACTTATTCATTAATAGATAAATAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACAACTCATTACTTAGAGGGGTGACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACAT
+
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
@r4787
GCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGA
+
+B$"(%)8C.3$(;;597'-3.$#4+'%D2:B18C)4@=!CA6C=!3?H;'<28<*:G(5+8*=3<1*=+0;=)H+5@&#70'-17BA-:C"/D.C"5>"9@$&<(:B9*GD!8E93#4+BA/!
@r4788
TTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGGTANCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCNTAAAAGTTATAAGGAAANATAGTTCATCCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGANGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATNTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAG
+
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
@r4789
CTNCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGANTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCANTCGACCGTTGCAGCNATATCTGGGTTTCACTGCCGGGCTCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGNCACCGCGATTNTCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCNNTACCGTGATAACGCCNTAACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCGGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGGGGGAGGCTGATCACTATTCAAAAACAACTGGAAGGAACCCAAAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGANCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTNCTGGGCTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCNACTGCTGCCGGTTTGT
+
+*%!)&""$)'*)#*&+!!*()*"!***'#&*)+#%'*&!'+&)"&$#*&('*)$)&"%"*+(%(%%!%!!'*#!"$**'+($#"+#%))#$+!*!+#$""#$%)*&"'$&(&&+&(%"&"!(!%#())"!'+'&$%(!%!**"#+*)(")*&#&(##"(*''!*(&*(#+*!(+%'!!*#++&)!(*"!%''&'&&"&*!('#*&'!$#"&%+*""*+%++&#$'%!*#*$!'#)&%#$'"*"%+##&*%+)&'#%'*#$"!))(#+#'())+#'''%$"#%")()'"+&%)&#'(#!#!"$"+)$$&*!)$"!!$&))*('$*+*#"#"&&$&%&'+#$$(!"'!"!($&("("+$%$#((#((#+&"%&+%*!((#+$%*)#%!$))$)"&("(%"+#'($#(#$!%!*%'!#$&"$)'!''$+*)(&#)('&+%+#*'#+)('*%$*)'&((+*"+*))$%")!#*!'('+($&%+%++*"&"'%*(+&""#$*)%+&'&'""%*'"*&$))%"&(++"+%$)'("#%"+$+#'#"%$&+!+&(%'%#!+(*()&+&&)#*'$(*("+#)""$'$&%*!+('(!#%)&!'(%*$*'+"+$()#"*('('*&)&*!*'++(+$'+)!)%#&"+#$!)%'!+*')*%)(+(+%&#%++(*%(&)'**(((+%$#"$#!"'""+$*"&%!+&'')"'!')''!$!&$)++$*'+!%$'**#"&'#&%&+$*&($)$#"#&"*%(&&!#+$"$&#&&)+'())##+!)+&"!#&'"'##!")!!(!)'#(&+&%+)*#&"%*'*)!!!)&'#'($+*!!'%!#&"%!!(("!$#+()$&*'*&"*&*)'%'+)#'#&'%)#$%+!!!(++)*#+"&%!*"**#+"#%#!&&$+*'&$)#("(+&('%+()&))#!$"'(()!%%%$'!"(
@r4790
CCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGNATTATCGAAAATACTGCATACACTGCAGAACGTAAGCCGGAACGCGACATCACGCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTG
+
@:*"7.&-;D%6.-@!01?4#H92D5.;.5F<6:EF>2>F8++%<2G.:H2;>2D/3(,5#EG43@#"';"A9;=E9?'>932!.F=H4.A&E"D&.#"E*0.5)!71252E?!32D<"<$,A)+9B:>:B6<=HC%;5=.1F:C
@r4791
CAGGGGTGTCCTGNCCGGCAGTTTCATCCGTGTCATCAAGCTCNTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCTNGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCANCACCATCGTGTTGTCCG
+
(H.92#G!E/>7$'=?+(@4:'+=(1A(*'9A@!1/H0G+47E666<;$5)?C)56)H%13%3/,>#!(7@:/9D(2EH6@3-@CB5,GD?5D(1"B09>#B.A,?*?82G(:B>E=0"5=81#%E#1A!";"6/;>',5@.:6A*.B3*(&75$9@?:"&2DG*8+4(E5"/F3F"!1FDD<G'%":3:.2$!53!3<@&(6'0@@"!GB%2?8AE#%0<'4!:@>!("?#B?8E!(1;9D:!+&1&9%&H7'F)0*C5(8H'>**A?A19BE(@/6:%1%80$E(=%6B<#A721"B:E8++@8F';04)1@0<,4DD91F5,&A<5F+/:@)H#>B$<(/201''!G"(60>*9D=DE-'3.0H<.'&><=1=+5,<7@2D*@0-4@62""69G9<E4'!G2G9+=17H!EDA<H'C:.>;4
@r4792
GGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCANATATTCCGGCTGGNTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGANGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACC
+
9G1<,&'86B@/71&29#E+#@C)8C'-GE9*5=8?+:H0E)=.)/!<BE78B+1<)2G;/*99229)6<1"A!)40E@E2"$>B5F-#E=A?'7&2B34C:+)9%:-;;"1B<C+/;+5#3<%@)&>*0)*AA-596)-(%B4;"-2(!0!&5.HAC?35)G:H(,##C53+"558,2C</92';)2+04D#80=;5#B<:+3=!!%;A*4!D,>B5///29&4B=@#F-;1F(@>!4CF:?D=D'7D*#&&=B5C<0%'%-H<E!391@$A%F"6*'@"(G!!-11!"F6F$/)D9;6#@?#=B-0B@#=8#98?(>+53D010'D3>32#(<<+=2->.,-7,4,C3B
@r4793
TGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGGTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACNTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCAAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTACGGAGTGTCGCCAGAGTGCCNCGATGAAACGGGTATTGGCGGTATATGGAGTTAGAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTG
+
28-#;H*DC7<)?E090@@80&6E--'./5:*F3-F+17*(%!CE#AB3+>":+*(>%7"#7GF/34'12=':E$$B2=H)8G%$536=#F/1D<$?>>,94G>"B#%?4B&(:%6.-3>$AH:)#14&#&F/.4?6@$7*=.6D&7H7H0(##=,57'>=<A5>&$82=G64D8G??$:E'>@5A;!?:+"4C964.%'A="4E&H"63!9B285+5#=$E6>%"?7D*5*G<@BB?*(:4!,)@D#@,:9164(&C)@#.#?E'?-6'=098720*5.D0#(D!3*5>H#,3D-"4$D:42A:F"&+-3E@1-&F;F/6&.<3;GC,*+=;'G''',?#:?+,G81?8B%#:A><>E5=&E3E/!A9(E5'53!,H+F47B,!6HE'?!<<'0991G<'&(#:22',8#=9'D5-,2'EH,!-F0.,AH#6#8AF;+".494+B72#6)<"HAC95C)18,!&@A+)A>+
@r4794
NNAGATANATGTAAGGCCAACGTGCTCAAATNTTCATACAGAAAGNTTTGAAGTAATATTT
+
"!*'(('&+*++%"$)!+*#&!'"&+!!%)!&+$"(+$$!'!$')+)))(*$*$)&)&!!*
@r4795
AGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAA
+
>H3H$0:>D"DE%:&5+B6.,.<$!?%!*$6/0::;'A<0%%*=E8=,(1"#3":"7<@-%8.!FC"7>#+B1%$G5E#!&2%#3F#8@%B@+78$&.A!-%C&?">7?!+:1H>$0&993C4'"C+F,;75C>956AFB4%468$:>"0'F</C3$)2BCD1'<#;H<;AC"HG8>1-G0",-B!,97D<8:3.4)3H-2*:EB-##+90%C9+%H0C3,=F1*.=6&3/H=8*96CC*>/:9061%7%DA:@(E-2C8/D85(,65D8&"':+(35HH;55EC<3C*8#@/"!>F6;'.'=!2F;@@G@!:C-HG"F-.<5>/''8DEF;1="?.D<&(+B1#-'(?B$:9'9A?HF6@2<=<B05/3+BAH#E)@A;A%!5"A1/8/;EG1F'>H+",C6#=D$DC)HD2&!'4!/H
@r4796
CATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGNCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACNCCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCCCGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGT
+
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
@r4797
CAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTG
+
FFE3AH?=>4.C/,D&,*!;5+?-2)CC!BE4(*5:H./6F9>D.*>0@*28=%DBGD"1H):CF:(83*27!
@r4798
TTTTGCTCTGCGNTGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTNTTGCGTCTTCCGCGGNAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACNACCGGCACTTGATGATGCGTTCGTTTCTGATGATATTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCANACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGGCGCGTTTTGTNAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCACTTCTGC
+
FA0:FH8>)*$>#3,%*D4B,H7-94=#)4@5!.=<5BG6C(+1:5CC?+<59+0.D384,E(%A>:"H8(%CEC@7"3#99(4!$#@(/<D7%07FF<77>D3>3B<&;<)!H##5/,9&@!4C-$=GA'D!E1$3"=C@E!F5?52H+21*.2>D3927>;.!=6E;!B!!-5/G?*-F$#@A#&;#(D5))D#3$31831&A:-,'DE0@6;!)A$=4:+<)?+4D-?@0E*6B,G<#%!#('F#,>,05'72&"FC=)>'&/G<$;*/E#&F=#.B$D%/9$FG9&7(7.;<-?,!'G"C=G/37FD>#B5&,#B;=G127*)#?B54)A@,:G%-@.A7,1'6C:D#5)*;27#9+G+(11>=@&-&2*C;%7:='3G%+H6CE0;D:E.;!.!,#>EC%A@4"(-6?8HHA%96<3H!,*@H"!-"&#20;74+#)5$35H*;1C#>58)0>+#8F1-:8
@r4799
GCGATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGNGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGNAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCNCCGTCTG
+
+!%&$+#&*+$)!"$++&*%$%+'#*)!%+()%))*$)#""+$&#!%"))(!$!(#*!"&""&%*!%(!"%##'+!&'&'+!+(+''*#'*("(*+)(%)'')##%'*(#''$%##*"&#$%'%(''($#'"'&&*)"##"#"'%$++'*(!!)#*')+$'"#'&*!*#'+%)#""$#)$
@r4800
TACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGNCGTGGTTTAATGAAGGNGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAG
+
(*#9&5G:-;336)A>71#'>);&C95+7#(0!1==:#4&!A0$*.:"A2C,1:*(<F&-%+1(%H4=8D%01=:'59&F5D,<!BC4"/'1F%#/<A:$.3.05*><"=7B5"?"9B9080)>84,#$(A=#8/574.00$2*74F112#E,989@!#(/;+,#,?*39??&6?B;*<..E.'65%8>73((&$&6<A?D(4E6>;;&C64%;)3/A7('--11:5@H721='%EBD#%,#+*&'AE+#0E,98,G/1F#A%C.94F0$!%H1$&*E>@*C&CA4)*)>EH"?"31$)"-E"(C7*C'-?1*"*7>E9.H+%-7.4"-1%9A=E4+,81C"7;A?/1%>87A<">3B/!$608*#GBA1%86C3#-;1/:-H#@F1D2
@r4801
AGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGCAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCTCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAANGGTTTNTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCNCGCCTGTGCACTCTGTGGTGCTGCG
+
>+/A;C./7+C5$,;D"5*1#:5A0?7$><HAA&=@2:D0$=>0$/,85G80$9H2144+1?AE+"B+8;1G5<>$B<:F&.4*2+14!$C66F-#6*3*'#)950E)2+;((-F8>6?6DH#":!;"/*2(8F,<5%"7H$?5C55CF/''2@<25)4*$.B&#F>/!1:5<,;4BG85A.",+$&B:;G7/,.;1#;4-F)H=0:#E5A5/.4,CH?;2H-,H*'9!31H<30;&H6:3&;B*!B$6+F:';0A!$%B$.,D96&A90'6":'$-F3F('=&38!0#G/0/F>D9/F-'9.2;B=E*A9(+=484,!&@H(?G;E8/$#0;8626,#AF*;GG!#"B1,4<14E0$A1'47304#C*=-<.;/5/?C#FC6-$D/#)1:!9(??1-<B/4.?CA29=>360'@,-%/%84A.F!(GF>#;7*C%.('@>>/D=:C"#=@*37-0,#G>3G8?*4'B4+3,+-$2@662'.=E<151@@G&
@r4802
CTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCNTGCAGCCAGTCCGGCGACATACGGAAA
+
+$)#%)&!"##)+%")"'&+$$"%("*(&&%)&*#'""''*#*(%"('$*!*"!$'*%+"''($&'"%%(%"*&+!(*&"!&*%#&%)$)*%'
@r4803
NNNTGATGTATCAACACGGTTCAGCAACACCCGATNCTTCTTCCAGGCTTCCAGCAACGAGGTT
+
($"0H;A>>C=@:0C9).2'%)E5(+#++#F69>8/!:1%'%629!%+$/,7$08AD#!H*CF;
@r4804
ACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATCATGACAAATACAGCAAAAATANTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACTAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAAT
+
B"5F=DC&%A(#A58,'3C%H0@&17)-/A<?",GA<.$+3(-:</%*-7?!9D831C%A,!7'-;509"8E*5FG0$+%5#,BBG3(DD<2.0$;>/6.0FH)8;:A%1')4+$+D$<:@(-(81A0+4*98D64@;B73@(46,G7<HD/#6(1218;,C!A/!<8E.5>7$:GA:36#AGE?:;;B18?<19-$-4D37$!''/48;,##;GA,CF$/A514F1H2=#B0"08+(:3!6$F<=/H+3H7+100G*2>$!CDGA9;3GGF!E'3G?4+5#"'6,4:$B0<!3)!D#'4E'&625;%,.)(=/F1B#:=CE6$.'3C99G9,$-D3E5#$"=($''!/!#A?
@r4805
TNANTNTTTGGTACTNGGANCGGGCTTTNCCGATNCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGNCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTNTGCGTTGTTCCATACAACCTCCTGAGTACATGCAACCATTATCANCGCCAGAGGAAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTNCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGA
+
*%'$#!)%*('&*)$!$(%!#**''"("))'&%(**+)&***+))$&!'"%)%"'(&)"*)#$!''!$%!%""+"%*'&(+$+"!!!&%+#!*''%'$(&()("($"'%(&!!&*%*'"*#*#&!!*'##$$(+"&+%*)%*)"(&!*%&)$'(&*+("'"%$'&(!%*$+(#(+#+$+!($(&*'#('*)'"&'''%))&!&$)(+#*&)("&"$)))#"+*$+'!#$%$"(($$"(+'!*!)*!%'"+&)*"#+(*(&'*'#+($'$&&#)+&$&!!"$%()++$)%#+%$!'#'%(('$+*'+'&+*')$"&")#%#($!%$')'+#$(%#"!$$!#*))'(&%'#%(&($+*+)+)$+$$$+$)*!'
@r4806
ANGTTGTGNNANNAAGGGNTGTNTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGNCAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAANAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGANATTATCCTG
+
(!'$*%$%$$&*!'(&"&*((#"+#!*)"'()!)#'&$(%$('%#&''%*&#(")$()%)"$(')+!'#'&$%(+$&+%#!!&$**')*"%"!$$%+'*(#*'#(+)'(&%%)!))'%"##&%(("!&$'%#!(#!)!$'(($!%%$)&)&)*"""*$""'"%!%+&$#'!)'$*"$)*+'*&')!''#+&*%'')"*($*&'&!()*%%+%+!*$!$!'#("&&'&)&###!)*(%+)"(%)'*#%&)&&)))+"$+#*"+"#'!%+'!#*)$'(&)"#+$('"#**"#'*+(+%*&'*$"!$'&(#')*)'$%**+&##!)"'+$!'#%+&$#*!$'*%)"*"*("%)!'*"&)
@r4807
ACGAGGCCGCACCGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAG
+
#,&.G(48-#"!H8+F;*EGG.-%/F1.=$5)@G'?'(+;2-%C,+$5C#D607.&@'6=DE1$.D52$6+6':)#GD+(2#*/*1F5"ABGG(F-B,-B%$7,D?(<9F8,07+-,4(:HD=6*1'#11.:.""6$3!2+4%34A#C>0"7GH-<;4@@>F9G44914@5);3@9$C7G3D#*%HC(>A'>/=E,H63'/9@'(0))2'4A8'(3(8H?7.=(D%0C!AD=)")@7D490EG60;BH!ACG3+/(9:(E9:%5G*'/,CC);"E8:C>48!.3B"/#0.H2F:F1-E-;4,.39"0)E=&2A+
@r4808
TGCNTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGC
+
**$+'((')((("(#!"+!)"+*##"*')'+%+%''*$&'$$)%"*&$)%)%%*"#+'%$"(*)'#)$&"$$$
@r4809
ATNGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACNTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTNGTTGGCGATCNGACGCAACTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGT
+
%%"+%%)!!"$((&#!*'#$&"'&%*"*)$)*%**&"(#&+++$*"&"#+!"#'$$&#)%$$*%"%+*""#+)$'++*)"+&%#&#!*&''+$($*)'$*'&!!&()!#%"*%*(!&+"(#'#!"&'"(#&%%%"!$*$$$%&)!+#!$#*")$!+)!"'(")*"!"%*!("()
@r4810
NTGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAAATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGCGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAANGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATT
+
$%=;27H7)&7E/>$+C4*H45-<H8<#C%%8.<*((9B4'C++1.2!81DEB''C>='%44/G"88<%(82%3+B8')A8<*6!)8#)DG=%CG77.:.E.F+758?3?BA!#,<$&*F-6C.:A*"($>E/+,5G/F,.$G6H%,A8(0%DA0*#$5GC@5,H+(F$8=GHHA'?"?C"").!C;H4)DD49-/"5?6B<9D9D#;#<"+2<"*"%!?>GF+@CF9HD8%!36"7*H1H62+"11(?C,;B.?/GH=%35747<)F4-GF%F05*H4;/*HE.A>'@*!!54+)E3/&)?(<"):D>FC<;G+A2C?&02,6.$'C=A#
@r4811
GCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGNTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAG
+
-885;.#%)0*F!/6>1/2D3G$,*F=8G,':F<D1D&!&*%=8!5C$.C=++)9.'G9<+;!$>$-*4"1/:<AH2F%"D!,>9).EA5C=+C(5+-E#,/?:BCA-BA0>6!>B$A;51>/@=!5:"+'*)1!2HC$(9/C6D,;,E@?46;&7!0DHD)@:8&$C=@=A@@EG)<&&6"4G5*&)#*A/24?:;&G7F6#A7&=*!?"6=E@*
@r4812
ANGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCNAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGAAATCAGTAAAT
+
*%122!!15+?A92BC1'?(5'1<-66.75@73:*45?.731FB4:;%!:?DB)/E7A))*C="6@#3%6:"+45$1:=?7%C6!4=$:$/"+42C*<1%7D%H7)8E,HA%E*).EGC/215G/)F7"B:!0B>E&GF"$B79:9D";;2>6@->G<"F2=*2%C?@9A&)'#5C)120;8(%?=*)H)=5:H"&
@r4813
GGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGANGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTNGCTGGCAGCCTCCGGCCAGAGCACATCNTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCNGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGNCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACT
+
+)(+1FG3+0:FG1H99&;B?:6#F':-<E9<9*F49H0=EA'717&3/$8F17=>>><)95!C-:;.4A0@90):2118B)%248C(70D5F/'E02$/&<@2#:7!F<"1#*4A%H'2*7G@3%#),-'0*F4='E('C/5EC!D=1<C@?@.6384?-7C#?G*'2?8+)?B,/)(#E5B:/-/;'!GG2!&87F/'%!@:7CG*<3;8::)((FH>2-:A="5%<G$+.4E>BA>B95#%10?6B68&5&60C.A++!<(-2*=,;'%;>@5@1<F:7&CA%<:/$;1'#*.?+C5"(C"$F)/1&A0A,>-BA9=D:("1*,=F.D0=!)+#,,$?42))&+8)?6.)>(;-$$)$%'*=D7/(=&#."5(F=;B;,-E0+;&%B?=;!8#1"!AB*$G8.24>B$&(9@76.#5:CH%=
@r4814
TGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAANTAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTC
+
1A&!;-"4!8#C/477&,7C"696++B%?H8!*8+>@6C6%,3D#A("C(,E*C%.&HE533C'(&6H@1C*(/:C#6,!6!4HE"-*.$0@4)1$)6?/16*GF>92?+H,=/5B'%%7<2C<-1&:>@+58,44)12!G?-D8=;*2216=%$AGG2))8E)0DF?42C/847D04-.#$@,0D09C@D?G.$#$"=>?-C.3),!@*%)*1%%)0>@E>>3?(4,'?H4(3#:*9=)74(=FA2+5*9
@r4815
AACTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCTCGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGNCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGNAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTNTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTGTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACG
+
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
@r4816
AGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTCCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGAGTGTTGAACAAAACTTTTTCCCGATGGATTGGAAAGCATATATTATTCCCTATTGAGGATANTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCNGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATACAGCC
+
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
@r4817
GTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGNCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTGATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGAAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGNCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTNTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCNCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCG
+
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
@r4818
TTCTCTGAAAATACTAGACTTATCGAGTCAAGAATCCCAAATGGATATTTTCGATCGCTTGTTACAGTTTCGTTTAGTGCATTTGANCCTTTTACTCCTCCTAAAGAACAACCTGACCCNGCAAAAGGTACACAANACTTTTATCTTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGAACTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAGACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAG
+
>;+(3?(D"@#.;?!??G$"H!"""H4&>3F1:4:30:B9G5)<(FGDED@"+>-94*G3%'AFCE4*3C*/#G3H5G$9!B$84ED04BC%*831?5H.:=6G6D$4;(8F/%C?1<D642?>7&@*@/E>E;9+B0!33F$!F1.'-:!.?D?B&>162D*4-@49(:;8:%=/4C@*:0C%,);-D9:347%+/&$G$A9&!F#%G))1)+B*'5H#(!G$?+&5G/'-B;%?>$,(?D#$(:=0*1629!20&9E#;->5(/;'=F(;6,E17,<?F0>?+&=;!FB78HE1?C3'B"DA7!.G95)>0/1<#(?#$+)'2*A9=:5C:!$=E'9'@,),
@r4819
TATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGNAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTANCGAATCTTTTAGCTCGTACCATGTCCTGATACAGNGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATATCCTTTGGNGTTTCCCGATGTCNGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTNCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACANTTCAGCAAGATATCTGATNCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCTGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTNTTTGGTGAAGGGAACGAGTTTTAATCNGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTNGGTTCCCATACCGTATAACCATT
+
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
@r4820
CTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCACCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGNTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGNCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCC
+
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
@r4821
NGGAAGCANAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTGAAGTTCAATATTACTAATNTTTAGATGGAAAACGTATNTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATCTTAATAAAATTAAGGGTTACTATGTGTTGGAGTTTAGTGTTATTGAAAGANGCGGGTNTTCCTGCAGTGGAAAAAAATAAGGCAT
+
!0>%82!<::8;0##H!F$89B-,&&"G?A>.03338)-F??B6:<?%-.#G*)FC!#B&*A.73-9"F=A86G&<;&/CA+<<7.D$%H)'9%G0B(>1!D@:&+*8$?7A1?1+&<2=.'/'+4/6?$=%EA12F+$,8"8/+(A121!1;H8=.%H&:,2+8B'H;@ED-G(,/A6>A(6(5!E19'(3B-*A/&4"1;,0&5!CB=4'>?:A0B><!4"(3;@C/
@r4822
GTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGNATCCGGCACCTGANCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCANAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCTTCAGTTGATGCTGCAGCGCATAGCCCAGCTGTTTCGTAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAAGGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCNCAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGTGGCGCGAAAGGACAACCCGCAGCTTGA
+
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
@r4823
GTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGC
+
F@,B)*;7<(D82#+DBH&)6*F+'@D<-+++FFG2A.%FH0E:%4@1&8?=.3(7%H4*C7.F&33'"%%>="5!5B($",;B)CAA8E
@r4824
CAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCT
+
=/GA#?0;&B#HD,&GG(/5FA@>!G7(,?3'0*C9',4,G>?;2+(=5!#>+E823*3/A,=A"+*EH(E==3>4EB'<6E.>?B..&%(,CC'2)::+B7AGGA,C93"@A/)GBD7%>"F0A@4.(?&G<>/'@H=9@;)G0<)G3126+$/(5C
@r4825
GCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTGCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGNTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTA
+
</50#A"(&C.G*"?8E>(7H5/1F$16D(F)*>H)G2%.D3*.7H),.B@';'.@-85*A3=632F:?/AEGH7<:D%#C:>)8%86/F,4@C9/B-17F>>B"5$1C;4(D?:??5?E*=F5G,(#?&B<C!5<60A-,12B-&7$98B107)@B-C?$)E)"A<5F%.B5.*'A>3%(1::$B.F@'(*5$7B;.1,DC2H$:"@H;<2*>4G!6)641&*90*-+'C/+!H@&4A;??(+=+</$E+6EG?B7F&0!=/1F%E.@1<%22F@E#,'-
@r4826
ANCNGNANATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCC
+
(&%'$!%")+'!)"!&&$+))(()$$%+$+)')"*+&$%$$")$*"$+#!"&))'$!%
@r4827
TGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGNACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCG
+
.C.31-"F#%./5?BH0/.+$D7A?363H,?)<5<#/.AEE;4$#D,;!#>C2#CE:38H6(8#*26CC1C$!7<?22>D<B:>G9&@D$.,!3<,$;/A-'6C21:"=?316;26/-C()AG=):C)>G<'F%EC'#(H/"AE7""2#0"A:.*5H3H8;G-6@,$D*C;7=G&,7D/>=9<8.-%B0'>@@.74)(!%,>7&0D7#5B>EH'E,H3@,0C$A!FDAF%';F=..&05@":5@F:1A-&)B%&+?<!/$>@>24+>D8,G,-#E('%1'&$0$$E.6H23&0+;;9+FA/&:'E>49=2!!8!;%22,<2GF:6,*)#468**#G'>C;G0%@C"$7!:D8*0><=?5D=C%@4G+80BA)G(33'HE0,/:=8G(7+!+<1.;80;.7A<>3G;:F%<:?/,F/&5).2<C:'.E9EH#0*96<-#F$,%=9<6)5%H>A,;6@,HGE6<D;
@r4828
ATCTGGAACTGATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCANGCACTGCGTGAAGCG
+
4#33*'->'@EFC$*>8#.D:E>-*5;*.-3.746.7%$B")G.6&/1F-16#>:@0<?;*->3G0?-1'
@r4829
CGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGNCTGTGAGCCACTCCGGCCATGGCGTANGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTGCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGG
+
*A-D6*0*D#;<1C233E<E-*97+2FE)@CC(AC+19B)+*<0"2=8BA<*))1$%*1007$+'?.F=)?-(/44?7A%155&>'B!B+F586A43#F!D%!<G=4.5F+03&B/2BF&=G<D),2G#<92ABH33+9"A?-HA6%&<+#//11H2/-@/5D?="-!7(+2;7*'#,+"!@'-E@(:D<D//#:245"C-<.#@7=@8!ED6'0*0;=1.C%9";E.)H?H5=5'*?FGHC2!2&0$,-<:8.</7%0G;*-;@$.<+??%/-95&-#D;A=-)=?&
@r4830
GTAAACAACCGAAGAATGCNACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCA
+
+(C">403&:G%&$*G841&;@:#6<4<:2&6>G2/HF+'G)*$=:7E$)B9F><@C.$)F:"3>@19AH'('G96+DD?CBBB(,G!27)+F:=!5&F&:A1<<*7'-5;8;>F:F1F?F'D45>*5&<+'E=#032%<>*:8$=$+<
@r4831
CATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCA
+
<*$//>8>DGGB433B:('4B&,89B-:,-C89+@E4?E1GED35<DFDA>#FF?F3D=:#@C+7=H2<AH/B/D!(4%B=0#6.7'B7>A%%%(51>"C:8#<53#;:A3>&=6F$5059&349A=8,A
@r4832
ATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCNGAGGCCAATACCCGCGACATANTGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCAACTTTTTNCAGCAGCTCCTTGCCGAGATGGGATT
+
:-#)''3$)=4!66&)/B$8@"91>.5D5'$A!3EH2(==5:'A/6A9=0;@;@;>:G!'5>>>>C1+2=;4235%7=>>4BA(0</"%+A7=,#9!$),@/.B?3&=44A?GH0DG=%)0%E>+!43-$>G(H2'A.;E1F4+1#7.5D@63=%.H24:*B6+$=</H+5C(;&+7DC!H:45=B7E&@F'"!.3-12:05E;:B7:>+?%--$:'=C0G!0-'2$/H?9E)=?BD.**4:"8D&<:?!/16$:28AD'8D;
@r4833
GNACNGAAANTAACTCAATGTNGGCCTGTATAGTTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGATAGGGGGTAAATCCCGGCGCTCATGACTTCGCCT
+
(#*&%)#*%")*#%*%"$()*$+&"#)('+"++*$*$%&%(%%!!$+)*$(&#%)($%!**'$!&!!(##+')($++")'*$#+&'*(+"&*'%$%(+""$#*((&!$%&(*&+$')*)*#!(##++)&+""(!&'%%"(+!!#'+'+!+&+!!%!(+)+$!'("&
@r4834
ANGAAGNANGCNACCGGCGNNNTTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGNCACCGGCGGTTATGTCGGTACACCGGNCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGATATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGTTGCGTGATGGGGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGAAAGAATGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGATGAATGCCAACCTGAAAANGTACAGCGTGACGCTTTCTNTCCCCCGTGANGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCATGGGGGCTGGAAATCCTTTCTGTGGANGCCGCCTTATGAGTGGCNGCAGATAAAGGTGACCTGCGCAAAATGNTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGT
+
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
@r4835
CAAAGGCNACTGAAGCGGAAAAAAGTGCCGCAGNCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTC
+
?HF)3!17-%,?4.!FA6%#FG@8,?%%:,":1=.2@A=;?7:H6.:2&->%=/7$HA/.?(##F$@6H>===F'!E..?#7>,?!AH>=9-EE4;5=:;'D+CH'737/(E-4#D.H=:?.%8/--1BE
@r4836
ACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCACCCCTCAAAACG
+
H6B%'@)H;)*!)G0=&2=;*4<!D@1.49$@8((>=,7!2''F;9/7HF%-,4:,-@31<B(+'=84<1;#EC(@<D0F#!421E
@r4837
ATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAANGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCGGCATGCATACCTTTCCGCCNTAACTGTANTGAATGTCTGTTATGAGGGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGCCCGTNGCCATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTA
+
$-0C=")/&5!FHD)C@"<6F9?62A,#+*B#+D"#G2F$2#FD+'<)BDDCB1FC",''0D23E'HE+38%=@@@)%2;"&?.5='*8E@7H9$B,<G4?'DE7#81?-#+9,473419DD@A#B433>C3.-D96F*!?9G)0@,>%:%66</"3E%2.G;.$2/CE8/=/1$H)4F'&=,%C(2EGG!/?F1*H+1$6G*%4H3/;D$A3,$6(2<>!0769"(,%(93"CEH(,D#A01*A8-=:<;&(7A7G0/0F$1(D'3)"E2);+5?H;(8!)?"'9<0%C5?*(DGC)7>08$6->:!3GG07.D(>1DCG0@?#(F,3<"F;=+##<)7A1G6:+9F+'1DF&"/*;@#:5BB463D"1)*5B5A$&88!?#?4%).$3B-3)D?G*>-B&&%7C&CEB.FG33/"96351F<))-F;B)!>9)31.9F,$B79,D.0"$H
@r4838
GACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGACTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAGAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCNGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTA
+
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
@r4839
TNTGCNGCNTNNGTGNTCNAAANNGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAANACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATNTTTTGTTTAAACGCCNTGGTCAGCGGCACCGCCNTCGGGATTTTCACCACATCNATGGGGTAACGGTTTCTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAAC
+
&")(*")'!('#*')$!!*'"'!%&+""*+%&%%*''+$()!(!&*""$&(!&*+$))&*))&%!+*%$#$"&&(#*(#$"'#&%$$+)++)")!&*#&"%"&!&%'#('*)''!&''&!*!*$&!%#&*'!*"'!++(&!!++$)$(&'!)*)%!**(#&++)')$&+$("'!#!+'***#"(#"(!*#&)"('*(%")+&*'&)(!'))$%($'$)*(&'!*+()&%$!!$'$)*&*'"*()'((#+(!$"&$(#)($(+$#')!'&#)()&*)*($++&'*$%+*%&&)&*&*!#%"****%"#(%&&("&')&%$*#!''+)'((*)(&%!')(*(!$+)#"$#!#$$'$*&')!+!!)$%+(%%%"'**"()(!#'++&!%$")"%&#&'&%$)!*#'"%&)%&*%*(*&'*%#%+*'%%$!++&"&"(%*'"#%"%(!(*%'#*&+*"'"!%*()++#&(*!)!)')&%&)&)*%++
@r4840
CTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATANTGTGATGACCATTTCGGGCGAGGGAATT
+
,&#,1:(AF6G*8:!:,%3@1,H+-3AA#'''8%.4?7*+)$-A8E2+&@*+*$>/'';BE8>*8.!3CA55!/@EE27:57674@<H:2
@r4841
CTTGTTGNAGATACGCAGGCCATTGCCCGTTACGNTCGTAATGTTACGAAGATGGATGCCTNTGGCTNTACCNGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGGAGGGCTTCGCCATGTACCGGGCGATGNTATTGAAATNTGCGATGATGACTATGCCGGTATNAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTTACGCTCGNCCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTAAGCGTNGAGGTTCAGGCCGTCNNCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGTCTGT
+
+:)G!-F71GA4.?<FGA92#8G((B/@$=-$@#387E&EG:)+HE$/)='%-+FA'<77:1%6.*1B(-C-#A@1F:)C+%*1A37)'43D:$"D>"A;H1,1"@&'7CC(A0;6G(>8@B575@83=*6B-2;7C6+!2%1,H?686%2C/%?0@B$%$7,BE"/$!8D*!D4#:5<?.#C7!+-H.D@7$:&3?16D+B6/@@%>6:+:EC8'B>;EB/A9D$A=&=/@(@?A$,=E<A"B;6%9*',&B;E1/;@17/@*8<C8:5;%12$6(??++(+F%7(0#4GF!?B:;(A)819,65G@FGAH"E$!-1E.3/+E>B4)&GA4.!0<4)2/H4D6-@4".9G+'#<@:!#1H7C;H);9,.86.3A/&C48:<4):<82!")>15!2,6)97743&@87045+-B,CF/#AH*2-%9>)1.#:753):9?&>7701%)1?4<055'@C,F1-'B4H=
@r4842
AGCGANCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATANCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTANTTTCTTCATGACTTCCCTCTCCNCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATNTNCCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCANACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTNCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGACATACACNTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCNCCCATGACAGGAAGTTGGTTTACTGGTTCAGGGATCGCCTCACCACNGTTAATTCTCGCAGTCATATGGACAAGCTNATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTNCACGGATAAGACTCTGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAANTGCCCGGGTGATGGCAGAAANGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACACACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTG
+
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
@r4843
TGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTANGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGNGATGAACCGCTTCCCGGTGCCGTTCACTTCCNGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGANAAAAATACTGTGGGACANCAAAAAGCGACGCAATGAGNCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAA
+
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
@r4844
GCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGANATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCANGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGNATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCTTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCNACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAANATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGNTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTGTCGACCTGCTCTTCAGCAGTAAGCTGCTGCGCNTCGGTCAGATCAAAAATATCCGGNTTATTCGGGAAGTGAACGGNACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCG
+
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
@r4845
TGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCNGGAAGCGTCCTCCGGCGCAGAAGNGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGG
+
)D9)!&:3+0?4B?7:E1-G'@4B;/2;&*<%''1<AD;F*-&>?;E)7.G$"3!4(A-".(>%@@:0@;*4&1#%0E=%,HG-?-"'B@4:*#</C/@*9.+.$1&(2*@,GC-F)>42'->)-3/)F.'GD7'#B5*@C31
@r4846
TGNANGNCCACGCTCCGGAAAGAAGTGGCCAGACATGNAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGACTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCNTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTNACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTNGTACTTTGCCAACTACGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGAAGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTA
+
&%*#"!$+#!("*"()$#("('%"&%#%)&#'#+'+()%&')!)&!!"("&'&&+*&$+(&!%+*)%%&!"!%!)*+&)$'#!"'))$$*"$"$&''"%!**&)+'&#!%*)+('+&!#(#%++)("("+'$$$+&)*"&++$#'*!'&*$&+%#%++"+&!"()+"&&'&($%%*(#&'#"')(+%%&()*'$+*+&&&%""+!!)(*)"&"!!!!###'+$&*#&*!"!!&*&'%##)*%$$&%'#*+&+*"!%#*$+#&!"#*)%!'&!+#$!'#$%*"&(#'+)%&**#*!)%)!!(((*'&)+'"+##"&&**%(+*(&%+'+#$))(&!%"!')$+)'$)*$+%()+"(%%#&$+"$#"#!'')''##&%$"&%'*((*)!#*)'+%'!)&!(%'"#))+&)%%&&!!!!*!)(+'")%$)&&'"!&+#(''#*$'&&%%%"$+%$('(!'&+#)(&!#$(*!*$&%%"+#"(++&%$)+)+$!**&'&'+%*"+$*()&*"()%#""%&&''&)"+%%')!*+%(#
@r4847
TTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGNACGTGATGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCNGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGNAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGA
+
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
@r4848
GATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAA
+
%/2!AH51?5@4@5<90<@+9<$768(@2%./+34;A5F/@D"-''#1344G:G93!+00G
@r4849
TATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATNGGCGCGGGCCATGGNGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCNGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTAGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAANGCAGCCATAGGTGCGCAGANCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCC
+
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
@r4850
ATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTNCCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACNACTATTNATAAAAATCAATAGTGTGGACAAGTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTNAAGAAATNTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAACACGAA
+
+759H'6C:G?H=,4#=&*3@;8H+185#//B!;9=<<E86CAH+H,6H1="?F?"-3%$H2H$&4:E+/>:.27>86'$D>E(!&F'8!@9<!'E=5%FB7B1!6@1:6%;<BG=3/%2182H'B.-./H@6<1"21$&$/$#0:18.3::.C'6,8&G$:,F'F767!6$$7#G?-:/AEB&2)%@*0#)831:7<'@@?!73D&29A-@/9@3FDA&!<%FA@A5,+>@/4.;;!H6(<,+;$8D+E@:77+&F22,F1/<?EG'*?6&:8B.9F":*(B""5->!;3F=&G%')/GB*H:E$$)76<C8;7
@r4851
TTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCAGTATTGCTGAAATGTGATTGCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTT
+
,?(D@A<BB':#@*#+3(=@E@?$AH@H($',&@464)@G"(&4-#/#A<,';+E$:*8,.-%82+843A#%@E?%>@CF!@8>/.-.D.AD$1A:86#A#$A."8),(@1.$AE&="'CA8)3#A"GD!A4/3$=
@r4852
TGTAGGANATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTNCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGCTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGNCTGGGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGNCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTT
+
%G5$$6D6)2G>F2,?%>>5.0$)#E2<2@A%@$B8H:63>)(20>",>&40%4B4<<$7@8137'3G-:C1B2D7/*9(7F5AG*=;&-?<0.!,)3,1!%?H58H67#$30(?#:.%,&4>8!&C=G6H%!'A%@#7);55AFA82?102193;-F+7>!#;<0G&H+0"/4*FF2=-%6>&F$-5(7,E88$*?5=(#AC$%"*4+<BB)8FGC.:=>5?#$E=>H&6;%!9/8F6'*AH,%%602&EB.D0)6?3?B,FHE9(F837(+9$)1!F+2;4:68-<&./7,D=72<=$>E=)3F9G5@B%=>E;?CF>-37C7+?C8H8;94@3@(3
@r4853
TNTGTTGAGCTNGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCNCNGCGCCGGGTTTTCTTTGCCTCACTATCGCCCCCGAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCTTGCAAAAAATAAANTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTNAGCACATCAGCAGGACCCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGNTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGANAGGAGAATCCAGATGGATGCACAAACACGCNGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCTTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACNGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGNTCATAGCTGGCAACTAATTCAGTCCAGTAANTATCCTCAATAGGGAATAATATATGCTTTCCATTCCA
+
+$#"+&&*("'(!+#)%!%##!%**&("''*%!#$%$*%($#))!*+'(%+#""$&+*"++&)$%!#%!(*&'#!&'#"&%+"&%%())(!%!*+(!('"+'"($%#$%#+&%#*$%(*"+*&%$"###'"#"+#()*#*'!'%*!('!**&$*#&#)((%*%)(!"$$#)$""'&""!'%%")$+&"%&$%&)")*(*('!"%%%)*''%+&*%+"*$'*'%""&+!*+*$$#)#%!&&&'("*!'(*&$**!(%#$"&(%$*!&)%&'%$')$'(!$*"(&"''$$('&"'&*'&&(&+##)')&'&+&*$"$%&*!&#&(%%%**!(')&!*+!!**#"'%$*!"##'&("$*#$!&(*+&&$*%(#(#+)!$(((+$$%%$!#"+$#%"&'&+%))*+&"$%")$''))!+%"+%+$#%)#)+##$$'$$+(")$)(%"*&'+&(%!'"&"&#%(!&"$(+))!"%(&!!&'()%#$%!)&''+$'$**$"!*"#+$%*(&!&&(+$#''$"#$!+("''%+*$"$$+"*"!%%+#&!))""&'$!%+!%&!'!+(+"!)+!+#*+$*(##!!')!")+"(($''((#"#*'$+++'%&'*&'#&&'%"((++)*'$"'%#!"'*'%+#)&&*$#+%%(%#%#)%"#)(+%)!&&+')'+#)(#%!!&#"&)('&#$'!(&"&!%+(*)'""+'"'!*!!#)%'$#+'%'!$#)!$''+"**%%"(#%"")$+&""'+$#(*!++'*#"%*$%'#+*#'*+''*$!#(*'%""#&!(!!*!#+%(""+#$!$&')!&)$!!$)"&#%+%*)''!()&&*($'**#$(+$$&$&"(%)')+#&)('*$!)$&)%+""%&*"%(&$&('(+$!"(#"!%%&##*()+$$*!#*+$*%"(%))"')&&"+$)%*"'"*&$$)'*)*%&!!&!$#($&#&*&($)!)(#$#)+"%*()%+'&$"($)!!**#&")!+*!(#!%&&'+#'!$)$$%&!+!&#+!#+**!')")*&$%")*"+'(#)()+**%'"&)&(+*!*!#"(&+$'&&""))*)$)("
@r4854
TCTNANTCTCNNNNNTACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCNCCTCACTGGATAACATGGTTGCCCAGGGCAATNTTCTGCCTGTTCTGTACGGGGAANTGCGCGTGGGGTCACGCGNGGTTTCTAAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAANATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCNTTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGATAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAANGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGNTTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTTCGGAAGTGAAATATGACACGCCGNTGACCCGCACCATTACGTCTGCAAACATC
+
%))")!&'(("(#(!*+'$%"'"'(*"$$&()!"$&&)$*+!(&&!!($**'#$!#"#(#$)$%+$!&*#(($+'+'(#*%!%#!)$)(#*#%*$'+()'*(&!%%((#('*#&+#%$'*+''$(&'!+&&")&&)*!)&+''##!*!&$+$+*%*"+(($*+"&%"$+*+'%+!%()&$**&&%)%$)%'%)&##"!"**'$')%"%+#(&')!"+%))#(%$$!+%%+"!#+*+("&#'$(%%(""#)!""&&*!"(!*&&+)+$#(#''%"&%)"!+#&)$)%&!#'(!&+(+(#$#&+'$(&!*%&$)$)((#*&&#)(!#'!#%&+))&#++'%)'(%#&)&#%%)!*!'!"**%$")!&*)*#)(#'!!'%&"*()!#!%!)+)$%")'(+!!*)(&!%$)#*&#%!")%"!"#+*'(%%))"(%!)+*&)%*'""*((%&&+#+&''%$'+"$)!*(%&')+')(#'+*"%&'$*!%(#+"(*((('*%(*#')+&#)!("%")*''&")$**)+&&'**$(*"!!*!'$&&"+$'*%!(+%%(()'%"%!$#&#!)%"'(++$&&&+'*(&)'!)"#)()$(#!+&&"!*("#&$!+((!'*$++)(%))*)&$!%'#&"&+('!*'(*'"#")!
@r4855
GTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTGCGGGTCCTTTCCGGNGATCCGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGNTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTCCCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACNACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGNTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGNTTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGCTCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGNTCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGTGGTGACCCTTACGCGAANCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGNGGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTAT
+
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
@r4856
CTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTAAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCGCAAATGGACGCCGGATGACCNCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGNCTTTACTGATGCCCGTTATATCTGCGAAAA
+
@3(G1,1#88"-;G3.D&79<;?"B)>..1!=$#BC"3AF#>/$)?6EBB)!)..-,20.:85-0/FB.,3%;@7:/#++7;G/+6;(.(:#,6,7>AD(1$8E<F.C06)?H9,:%D.=-#C?F&G8>D811H)+#:(G6H7/8=2B&64+045<(B5"+#%('#@-(=EC3=;97%=FH&C/%-?898(-GA550/E41=CC,#"$(18FD-H*,$$4>+88E17H<BC:0E@:$"F-2A3G<G(:)D>0*+D.H9221'><32'<>A*DA3(),EH2+!H(..,96G2:(36,*..#!(;*-D4BA8'8;+.8*>:"8%B1.@#'*5'0-.<::6=$D@)<FE
@r4857
CNGTNANNTACCATGANTNAGTAATTGCATGTATAGAACATAAGGCGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGNTGGTNA
+
(!'*'('"%&'#!%&"#!#!+"&'**%'!)&('%*$)'%)*(#!$%))*'!#""&(&(#%#%)")&+"!'!%&'"#!&('###&"#$
@r4858
CTACTCGTGATTTCGGTCTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGNTGCTTTCCATTGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGGCGTGNTTNTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCNAAGCCTTCTGCTTTGAATGCGGCCCTTCTTCAGGGCTTGATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTANGTCAACACCNCCATAGATAATTTNTCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTG
+
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
@r4859
CAGNATTTCTTTTTCGTAATCGAGATTAAAGAACCAGCCACCGCCAT
+
*3<"+=GE##4<@!"9EF.E."D+F/G36&C"H#/+DG+#":+'H?5
@r4860
GTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCNGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCATATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATCTTCGCTAGCANTTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGANTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTAC
+
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
@r4861
TGGCTGATCGGCAAGGTGTTCTGGTCGGCNCNTAGCTGNTAACAATTGAGCAAGAATCTTCATCGAATTAGNGGAATTTTCACTCCCCTTAGAACATAACATAGTAAATGGATTGNATTATGAAGAATGGTTTTTNTGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATAGAAAAACTTTTNTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATNGNTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATNAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATNTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGTCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGNTTAATTATCAGGAGTAATTATGCGGAACAGATTCATGCCTGGTGTTTACATAGTAATAATTNCTTACGTAATCGAAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCANGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTANTTTTGTTGAGCTTGGAGCTTTGTTTTTCNGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCCGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGGATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCNATTGTATTTATTGAAANATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATGAATTATCTATGGCGGTGTTGACATAAATACCACNGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAANATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGTTACGCAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCNGAATCGCAAACCGACATCACGAGTAGA
+
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
@r4862
GTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAANAGAGTCAGAAGCCGTGGCCCGTG
+
15*)&H6;3&D-"-,C2FH;1A>&/<:5A&/C;FF3+A21D6">+<=A.1$EE8A"E)#C)@79+/04;B"!%)A059?:>2F*1E&@":&D#&(6!7'=/'7'7G5)-08F*6%-=<1B%=AD%1)6E!'<'.90AA;"C8%;=)?("%#>2.G?H#=8,E=>
@r4863
ATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATNTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTNCACAGNAAATTTTTAATATTATTATTATCATTCNTTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGAGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTNCGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTNTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGNGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATTGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTACTGCCTCCAGTNCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGANATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAA
+
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
@r4864
GNAGGNTNTANNTGGTAGTGCGGNTTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTCAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCCCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGNACTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGNATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCG
+
(!*"(!#!%*(%'*)%)#&#''(''$+&('*%"&%"!"#(')+#!$'!)'"!(()("#"%$*$!("!)&$+'$!#(#"(+#(*&*#$*!)#*))!$"$"%$+"%++(+#!*%!+'$)%)!+$!*(!+)$"))$)"(+"*$')!$)$+%%*"%$(&(#"()!*%$#&+))'$+$"+$#(")%$'*)+$*'""!+&+!&"!"''##(("$(')+"&')%%!($%()&#($*$((++'#(#*'!(%"##*"'*%%($(%%'%+!"%&(#(#)&"++&##($*"%#%'%!#(+(($&%"%"*#'!)%+'%"")(()"$!&!($!'!&$+!)&+$+%'"(&'%'!#(!*(")$"&#'"%#)'+$(($*$+%"&&"!"&$$'%$(+&(&$&'!#%"'&)!+))#!%*"*'&(&
@r4865
ACACACTCNCTCTGACGTCACCGGGCATGGCGCGCATCNGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTC
+
03;&<0B0<2,A+B%&$<<1>3?$4*D*)$,92<7C1)6"49C@.2:C=+%B6666)<*=-:F1)>&C)B0".$;0E>!(@9H2.1>"G$?A.B<14%$%;6+77,/$$4%+(#D?+7G29(&'6G7$E?6(>';3"=D*:
@r4866
AGGATGCAAGTGATAAGTGGAATGCCATGAGGGCTNTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTNTTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATTGTATCGCATTTATTGACNCGGCAAACGGGAATGAAACGCCGATGTTTGTGG
+
('+%("(()"()!))&!"+%'("%&'$&&'%!(%#!***%$*#($)"&)+&)"$!*#+"%&"$**%')$''))$"#%&)'!#%*#((#)*$(!&!""#$)"#*%$#"$++&*)(&*&"'%("+"+&)$)!+'"*!%&+%*!!$#'$'")#&#+*")!#&*)++)$#%!+*$!+#)((#&$!+"%!+$%(!("&!"
@r4867
TTAAGAGNGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATNTATCACCCCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGNGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTNTGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACTCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTNGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCNTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGANGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGAT
+
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
@r4868
NATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACANTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGNACCAGACTCTTGTCATTTGTTTTNGTAAAGAGAAAANTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGG
+
"(7A.4:#D,5H)2>$D&1'@E%H#:G+>%%590F'!!H0'&F@$#(B2A#F;0B)/;->=!F13,0#E)C:>@'+7!1=G49A0)3"?%#&9;4401D"!AHB(3",8$3HAB9+9"!="/'6%E?#".83E6!H?+-B;'=B59=7-8:1-:#50F%)=&#C62<%3&+//&-685AF"D19:F??E;<!9DB0=+"7&+>B)H)>E1C=+!='*<%;H;FB"<".;6.7'?3B1:C*)/@-G/39)FGH,
@r4869
CTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGNACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACAATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCGGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATNACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCC
+
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
@r4870
ATTCACCCCNCAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGANCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCNTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAATCGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGT
+
7".888>3;6"D"H('=0((/D?9+@$,&/$+GG20"$-E1*"5.=B4!/C@@,0)9.-B65"GB>F/;,"FG5$1>9<&EF++31'.(0)-?H1:..5;?%")4DFAD)91*F<@@A9F?E2$;)%1.4(9H)4;$4F2,#G?0$24G;/,4>;C%"=6@"$5/$$?.G0))HH$H,<%$8D@HG9<'@52D62E5:%-(%6%*7B"?$$?C8G4E:'2#>E$77B1GB71(C=%E-&%G2<";H;#&8;:;:G3&'"G!>FG='+/EF$H!<?-#,%-)E5B9**(&*B5/=''F$;+2'B-B7@0F,;1=3GF@(G.&@3.1#*7:C'H!F;E0</*"DG1AEC-FH-5H'">2>@(9(C;:H447H3HB*38;"HH)!#C!/:-+45*$/+%->D;?71*%;7%".%2C>2;1"56C$4BBB'0@@:6;5,<C>50="?3((+:GD9$6%.)#4):C6D3--F<:.AF-/:>-/+@:323E<3
@r4871
CAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGNGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCCTAAGGGTCACNGCTCCCNTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTNGCGCCNGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAA
+
;=??4B5#+2$>465"<#=$*;;G&8<E$=%2!F$4"AF;A47.DA(;"9B6F1(8F4>:(557'#?C=0(G6%C20.=D&:+5B+@H7(.(-7EB$A!<',-%3)>$=$BE%2,.)3&(14C$5G%AE!>H!E,?F86B1-#=>@$4<0E"(-*&4('G(BEA;5+%DG90*905/+DB81$1HDHE1!9$D-'!C$2<2.++&HG,D"/#(FGE,2?@-9%#H9;1.>@7:.F&5#,G'>$@/*&GA)C946F7672$F;)D5B,(1@0:;EGE#F140%-D)@7$($GB"B36F='F7'=83/@7#75";.76:7&A9?#=7(9%%B7-8&>+3&"/A
@r4872
GGTATCCATGTCCATTTCTGCGGCATCCANCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCTCCGCACGGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGNTGTCGCCGGTATTGTTCGGGTTGNTGATGCGCTTCGGNCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCNACGAACTNGTATCCCAG
+
&*+%%+"''$!#(''*"+#)$**&$#)*"()!&')#'$!%$('%)!*&&'&("+$$)**))'(&(()+&$'$)+"#'(+'$"!*"+$)$#&#+)+$"$")'"+!*&#)&*$*+")%&)('*"(%)%#*)$!%%$!#()"$&')*+)+"#'+*)&$#""(#(+%#%!+"+#&&*&$"!!($+'*"(("+**(!$!!"+!)#!
@r4873
TAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAACTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGAGACTCATTTATAAACTCCTTGCACTGTATGCCGTTTCAGCTAAACGGTATCAGCAATGTNTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCANCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATNGTTACTAACGGGTCTTGTTCGNTTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGANTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTT
+
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
@r4874
ACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCG
+
>:C@#/9;AB.-,B#"!4<.-")491,7<(:?B7;(-;$2&
@r4875
CNNGGNNTNNTTGTTAATCACCACATGNTTATTCTGCNCAAACGTCCCGGACGCCTGCGACCGGCTGNCTGCCATGCTGCCCGGTGTACCGACA
+
$#!("")**%++)%%#+$'+"*!"!*("!%))$'++#&%#%*!$)'"#+&!''('*%**&)($%)*#%&#(%'#&"$(*$$$"()'*$!)$%#!
@r4876
NTNCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCNTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGTGCGGGACGTCAGCACGTCCGGGTTAACGGCGCNGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGTTCATTCTTTACCGCCGGANCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCNGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAANACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGNCAATGTTNTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATNTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCNCGAAGCGAAGGACAACCTGNAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACNCTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCNGGGCTGGAGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCANTACGTCTGCAATCATCGACCGTCTGCGCTTTNCCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATGCAACGTAACGGTGGCCGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGNAGTATCTGGCCTCGGTGGTGATGGGTAACCNGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGNACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCNAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGNCGANCTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACANCATGGCCTGGNGTCTGTGGGATATGCTGACCCATCCGCGCTANGGCATGGGGAAACGTCTNGGTGCGGCGGATGTGGAT
+
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
@r4877
GGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTNGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATTCGTGAGGTGAATGTGNTGAAG
+
&A0/AG1@9!=C4+3@)@@*H5-@4:A.,"<2A<$):</44B%=C"'C,D.:#HE=*+9*G?AEC/2&!@:/55B*5FAC(,/@C4C;D@F&<.BG2!>6-&D6$!H<:220?<E=.&4"-8,(7)5$
@r4878
ANTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTNCCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCNTGGAAATCAAACGC
+
.@5F@(0D?.5DE&#8=9<?4:."C)""D.6GC;A&),D:7GH&)7,C4/"'F,<("6<;AE3:'B:/%EE'.:8$9":F27H;==8@*,H:0H!H:%H?4C?B=E+AF/+#)C>5=3;:%G/7<9:2ED.*#!5B85?#</
@r4879
AGGCTGAGNAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGATATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCACCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGNAAAAGGATTATGAAGCGACGCTCAAAAAGCCGAAACAGTCCANCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATNAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGA
+
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
@r4880
GGCGGAANAAACAAAAAAAAGCCTGATGCAGGTAGCCNGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACNAAGGAAGAAACCTCGTTGCTGGAAGCTTGGAAGAAGTATCGGGTGTTGCTGAACCGTNTTGATACATCAACTGCACTTGATATTGAGTGGCNTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCTGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGGATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACAACACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTNAAGTCGGTTTTTTTTCTGCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATCGGCATTGTATATTGGTTTATTGGAGTAGATGCTTGCTTTGCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTNGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTGNATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCNAGCTTGGCTGTATAGTCAACTAACTCTTCCGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAG
+
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
@r4881
CNNGCAGGGTNCGNAGTACGAAGGTGTTATCTCGGATGGGAATNAGCGTATTGCT
+
&$")*#*)((!$(!$$+#$##+)'+#)+")$%)!+'!'*#$#*(*"#$##++&(!
@r4882
CGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATNAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAANTAATACGATACCTGCGNCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTN
+
G.(0,"4/&(&>:/884H9?;D3)76&8)<E&:G(0;@$0H.F7H!23HA):E=0H*#H(9C<#!,1*F-3-"E-2)="07'BC;&8&=%)!394G#F7!#2*$?;F:A72"B8;4&F+$)/AD=/38;'G)-)3#.56H1&D3)%88!E::F<#4$H)!;;-B*481A87'EH6,/..#!&"G;D(?C!%C><%(*=<:64!$#H(8FB@3/&)"G471;!F,#/$:D:)0!"##1.%;H/*E4<E6#AC?47?*?+3&+-$%!4
@r4883
CTCGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCANTCCC
+
'(+%"21%5+4B3:4==8*1,#.<60BB*EHE@#D99045>9E)8;E*/
@r4884
GGGCATCCGTCTACGGAAAGCAGGTNGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTNACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGGAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATATTATTCTCCTCACTGCGGCCCATATCCACCTCAANCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATG
+
?!:$C!0%9F6$A2/6#=&=$4,H-?+6E"DBE"7>+"/7'*B1$!@$7"9)&+$/&F7"213=1+$*?0./!3./.C@D!.7A?:;C>/B@?%"CH<'C9:(5,44;3"1,?;'%<,(+3*:9=*BG7DEB&46=:%".G:@2#F38)98/9<0A(H:"B%2&"721-A?D@58B*D0HG1)G.CE)=$G44C?0:=+1*&EC8DH3!AAED8$E=99B48A;1#4>?63@"G#.3G96>#C#)$+3D63#$?D24C>D>28/<.:H)A;6D/846A7775E&&3E6/G<2"$B45F!(GB&)+'43"!.:/=2-0686A6,EB((/89"11>':57;<A.>'=#'3AABE$B=23;!;:$1C1$3/9+:@'4$B7%!!)",<A)$#;-&=+C(0#,$9)&D$,@58.1E>9,3BG@959=4E25/61("/.G'#:CEG/0;467HC-?/@!?%EDC8E,!(C>8->@9'3C4;!9;38F+((>,F<*@=@&%+;=,!D%+05>&8?2/4-->0':->=$=AF;F%-6<E%?4CFH:688D+0,!94B9CE*D=<;?<3)>BA5A=+>%35E4
@r4885
CCGTATGACTACGACTATTGATAAAANTCAATGGTGTGGACAATTCAAACGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATNGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACAATGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTAGTGGAAATCTTCTTTGCCCTCCAGTGN
+
&B<:96E0(5/795A#/=+;1/8DBCH$*7&/.=?=<$8,9#;FD-2&6FF8D05%/".,@20-!9?3:1:$)2G%$B7FD+18-6/6:)BAD'%.#A%F/>+;E$FCC>DH(D/AH&1(!$<+/<@$(B=!CB0::B37+4@%)&#F91)%$@CG'-/(9/%A@;5,EF;#$%#30@/"%#!.:D=C(%-D),H',?281>8&,FGB!&*#"7G.98568G#6;@/)7#=,/!8C68@0!E.0$1CE+3G+:H60"*+%D)G6A@)8!(?9!;&(%#343.;C='F#1(BH*2"0?CG@,597")%=#5.FF;%?H:<6$1"E.$$8%<2658-9?1),=".>!))E3+@
@r4886
CAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTA
+
$G-C88+=#H++EGH-E7#1$?=,A3>0)6&E1",9A44CDHH/8<G+=?1,'?+HD&-F%*+#%?<*7'9F!D>;0'5='3!)G*=4#H+A;3C$.:/@1H#:077DD)->;.'D<9!94A:$0??.6)4+*7'=7G!1&?G6'06B1.H;-)718B-@?26F*GB!B/G3&>3E695837B2%G)
@r4887
GCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGAGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGTTNGCGACGAGTAGATGCAATTATGGTTTCTCCGACAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCNAGAGCATCTGCAATGCTGTGGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTNCATTTCNCATAAATCACCAACTCGTTGCCCGGTAACNACAGCCAGTCCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCNTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTNATTGCTTTAATTTTGCTCATGTAATTTATGAGNGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCANGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTTAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTGANGGGGTAAATCCCGGCGCNCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCNAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCNTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGTGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATNTCATCCAGTGGTCGTAGCAGTCNTTGATGTTCTCCGCTTCAATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCANATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGNGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTNCTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGAATTTGTCTTCATTAGACTTATAAACNTTCATG
+
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
@r4888
CGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCNCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCNCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGNCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATGTTCATCCGCGACAGCCGGACCGCTATAACCGCACTAGTCACCGCGTTAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAACGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCNCCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCNGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGNACCACCGTTCCGCCGACCGGACTCTGCANATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTNCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGATCAAACTCTGCGNT
+
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
@r4889
GATGGNGTTGGNGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGNTTCCACGACCGCAACTGCCCTCCAAATCCGCTGTCATCGCCGTGATAACCGGCATATTCGCGCAGCGNTGTCATGCCGTCCGGCCCCAGAANGGTGGGAATGGTG
+
+F4#9#G/E"G"/;>#2>:G:5;2*427!+-00B.@!2%'6%6("@&F(.--?FF66B.B(.07=0$"67-F585/3F6EA,4;09=C9F0$@A#.5:("2B,7F5%E"0B+959@(3D'>0&-HB457*%/:@388>#3:D51*2%/*D,%0*-F8*&>H/33#3+89@B=?"9%#&;"(84G017>E?>!32"2G$1H?)!(G)F>=F=
@r4890
CAACGTTTCTGCGGCATANCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGNGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGNCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGGACAGTTTTTCTGCTTCCGTCTNCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCCGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGANATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGGCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCNGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCNATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTTCCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGNCATGAGCACCGATAACAACCGGATGCTGGTGCGCCCCAAGACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTCCCGGACAATGAGTGACTGTAGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTGTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTNACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCANACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCTGTAATCAAACGACGATGTGGTNTTCGTCCCCAAATCCATACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGNCCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACNGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGNCAGACGGAACGATATNTTATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTNACGGGCCCCAAGGTATTCAAGAACATCNGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTACTTTTCGCCGTGGAAAGCCTTGCCAGCGCCGTCACTGTCGCATTCTTCGGT
+
)(+*)*%%(!)$&&!)#$'$&$""%)**+!"%"%)($%*#"''$#&*%+$+'#&!'!&)&*(("$)+&""$!%(**%!%"!&"%"*('%)#%)#'(!$&#+"%(+!#+)"*"&!%'!)+!)**!+*!#"$&'+$$'""#)#)*!$!$*"'*+*%&"&)##'!*!+&"%"%'+"%!)'"***%$&**!#$)'#!'#!&'""%#**##&&")%$'+!*!'%#$+)%")++(#!+#)$(&"%)+##'(!$)'($$(!(%*%&$(%*&(#!#)*&'()!*#('+)'')&!!#)!++'(&#))+%%&$"$$#$*$)+#$'&+#(&%#%!('+)#''*%"+%%(+#+!'#&!'$))")"('%*(*&!)*"%&')$'("#"&#$!"&$!&!('+&'*#&"*(%!)*#'"$##++*'#)+&*$'#*!"$&)$'$(("(!#("!"')!'&$&!"%')+""(&!"!*!&+'*"#(&*)!&!(#&!*""*#*(&*(!&$+#()((&!)($&"%!!'+&)+#'"&&**&*(!'()&%%*(+%%(!%#+%#(#!%('%*#*%'"%%&&+"$(+#'++($"&*(''!))&!)%($*"+#!(#(+##)#!+*%'#*()!)'&#*()"+%"+!*$)*&$#$""($()(&'#!""('&+$*)"+&%*'&!'#*+")"%+(%"%(!)"+#'*#"*)')&"+"%+)*'!&##!*"$#+)+!&!')!*+(%())#%)$!')#+(##"$))*))*$($(#+%$!("#$**(+$!+'(!(!&!'#)+%!#)!$"$%!$'#%%*#+!%)""$$"(%((**!#%")*#%%*#!%%)+!#*#*"&!*('#(!$"%*&*%%#"%')**)*'$%#(+'##&(!%("*(+')%"('$#$#&!*%)'%%'"$*(#()#+!%&!&$$%$)#!!%*$"""***"'#"#$'#)$(#!!!")$&+)#+%++!'%$*+)+"+*++!&'+%)&*$""')++!"!"%&'+)*+'($(#'!"$*&!%''(%)%'#!"(*$!'#'+!$&"(*!#)$*#+"')"#*+!''($&*&%$++&*+!#!(&)+($$%*'"'+%"*#+!$!%$!+%')*(+"()("$"'"%))$$$()'))!$*%#'(%&(!#"%""%*(%$)"%""'$($)!((*!"#%&+*+*(+')%#%#(%*"''"''&'!'"&#"&$!"&%%#$)%**"*)(+&($+&("#"*'+"!)$*'&#*&)"'&#*(%&%($+&&'!()&&)$)!(&$)(&&&'#!%$!*%&$$$$'!$$*+!!$*%$"+%"*!+('&$!)#"$*%%'*#$+&"!$"&('""#"%)!+$!"$&**+)'&!'#&(%*'")'$!'$$+#")''(&*$+**"$()(%%+$&"#**%)"#(()'!+%&'$'+$%*'!)("!(*)&+*!*!!&)'#!""(#+(#%""+*((*"("&&#"*+!%)#)(!'(("'"**(!$!''!'+%)!*#%*%&''"&%)*(%"#&%(%$$*)'#'$)$*("&*&)+!'#(!**)*(*#+)+$%"*&!$)%"+!"$&*(((#'*"%'#'
@r4891
ATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACAGGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCANTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTG
+
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
@r4892
CTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAAC
+
28)!9F>+">H6AE&;E9=3247@5!+D!B7+5>/+&C"9-/24.7E462A
@r4893
TTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAG
+
*.$7#9G9!=;!9,3!DE,><@6#-$#E,A@6&54::B.(
@r4894
CAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCATTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTACTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAG
+
8)B?-"3<(A><9C<#%*":.H9F4'0C7,9"*2'GGGE$A.%4C<AB?!=?20'20<G&C!&*3>;$>94536%/C;;.AD.)?07A5>,4(5.*@5"@009?$'F/;?CB'F<-."?GG;G"$?3:D?8-3H)9:/7&FB3*D55CE1C+F@5@"12D*$G6=65G7)BD$*E01/9A.G*2A7=70,/?#<??$/!"3;"CE<,'G%3#,!94.$-DF!832@!+>1,@%<&*30/3>34+:B12E7H+)
@r4895
ATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACNTTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATANAATGTGAGACGTTGTGACGTTTTAGTTCAGAATNAAACNATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCCAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAACGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCTGAGCAATTNAGGC
+
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
@r4896
TTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCNGGCAGCATTCTTGAGTCGAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTNGGATTCTTGACTCGNTAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCANTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTTAATGTCGNCTAATCGATTTGGCCATACTACTAAATCCTGAATAGNTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACC
+
>+&E3-@!0%*;E/8EH4+F@)/:>96B1E.4B!%(&97$)++'(E"4;::85>>EG9(728A0?6#FCA0EGE#A>(+?>7D+.A*;(*;)?3&B3E7!#&!DB)2**-28D7)&9$AF6DH*B;H:2H-.#8B6=%2);10'G1(:240/?/HE@-6E,(!E$1!-@%!,<94=@H8?$GB1&%,0@C=(>@;*9:3C/C6=.8F9(5."'(+4(:&=*33!C/"0"=7:+=H1;G:$F(88-!*4.(5@@+/5D@3?!(E!D)/*31,3$99@@G,)F+6.%;2>(%!&"??485A4H9*B&7DF?,)$4B?:8:'7@+>=7#2A5=94F::,>.&:F,D!(*C6>!A:'43,:F3F-#17)6)?"?7!0#>-:83&3<?E5<:2=4;?@(BH$'*)6;AD<7<DH$D7'E/G.28E+7H"8)73#',7CF1:G"F0!E0988>*-E"F4!0EG>D0(/-CD#;F1B"=A;.9:.H?C7GB@1)64D2@%+))8/)0@;A54>9=AB6H:76.-:D1>$<!/A@&67$C.F=E*(*@9"?%B%<82<EBHH0#=/04%),C;CG,6*!?;,;.6872"4,G"#"<5"?<!+B2D9G-B;2)>4&?<,8<EH*'A3!%&";ED;1-#G>%(;A<6/H-,+=8$+)>+0D<8::*&!>/>(9045,,,78G!;A(B<4%CB4BHA4C=(E29:;#5>3C)A2-*)8F$/=2:?B'+>'/(+$97)=9?+;2=G*02"6/,6+.:@&GD!&EA&E4>8GE#FB15,C=FA3>8$48D%97
@r4897
TGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGA
+
G=/+@B=DD$1?,#@:(799'5:,&D2-2&1D+1'<";3AC@9#'99.;&2B>@@C>2D(,'>?*03#%E"7:62:$8'5AB.?2D+%F"G842D1#,-779H@9@&#?*',A@$
@r4898
TTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTAATTAGCGAATGCAGGGTGAAACCATNCNCGGCATTCATCGTTTTTACATCGTCTTCGCGNTGGTTTAGCCATCATCTTCTTCCTCGTGCATTGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGNAGTTAGCGCACGTTAAAGCTCGCTCGANGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGNTATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGG
+
,>B#FEHH.+-4,.#$A)2%2=7!:0C7<8%8/E?24>C!7G%@H94/-3>0+3FEB/G+:6>:%A=(G+=01H%.<D#8-(1H##'*H-.H%=-82*10&$D3H9GB"6:+4'"$/H$,%A:#=$-A<-8,,?<<,D@.&5+6!./@0-4,4CH5F/.)8"H,6<=?7FHDBFC3<.<HB,8>;+1-=A7'5*%75-?"%"&)3C!422&-;;%#.)'-8$)9;)-=FB0!&%%$=DH0.8:%A5=B+/E>,9*%<A<EC"FC&,+%#>(1A!?5>;8*'/F7(B3AF($*;?.-'?GF(".7.E.7$C<H:?'5D$-<2E*824-8@9!@$?5189A6%,!7!.(@@1G34F==55//B%7E$HDB:A/,,&1&2DG2G
@r4899
CTNAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTT
+
'""++!##*&"%(&!&'&*!+!''($##!)$"'%*##!!$+#'%(#)&%$"&))$$((&&
@r4900
CGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGNTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATANTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTAT
+
<);$-)2-.CD8="H"/H&,,/2:2G<3#"G26,2#H)H//$%D4"AG)/C&:B>>*0G(24>/=>#A<)#(9!&G:,";8>%%%EB=2:!41%518,+6D/+=/27,0E=-9!#71?D7$2C4@81E842;=!>".%37'D524G)*&$*/AD#-$4&#A!F(3F6>H('32D%H?%:;E7'.+@=E/>EH&C7!4.#/G6,G?;0:0(CA,(B3&-C4";31%-D4)05?F%&5272H?!F3B0E"9G6&%2B48HGH53?/@&#D+52H@+D6".)5=6*0%.9&G/!E*%&3H8/!!$&3>;5,4
@r4901
CCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTNTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTNATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTNGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGCTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAA
+
,5C65B)B,<>H?)2<5A/.7*@C,!=!*%3,H?G75(7B@%$".)CE5;,".4DB?"C,$).A)BFC7);FA<<G3'=*FC@'H50;4-::6%2;/!*%*(0/,2CA,):6F38;D-9><EEF?++$';=$G<1'3(9@5%=2&8?!;2H)#:)>:DBB;3D5D<2.,48G2.+.,@C8>8:51'E0GB>$+9(+&/,&D;2260,A!8.;/)EH2&@90%'#93=%AHDA&/H)>E),>9E%<2)(C-<+)+6(6A)?&;((.&2'')2'E!+?(#C7#393*1"E>>:+2##CA-.$?1%$,)4*,C.:9;AA,3B!>-=E1EG+A'F=.$B<9#">0@.8:)+#=7-
@r4902
NGNTTTGNAGNTNAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGAAGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAANATAACGCNTGTGAAAATGCTGAANTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCNAACATCGGGTTGAGTATTATCTTACTGNTTNTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTAATAAANGAGTATCAATNAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTACAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGNTTTATAAGGCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTANTATCACGAGTACGNTGGAAACGATGCTTGCCCTCTCTNTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGTGGAAATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGNGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACAAGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACANCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTNGCGATGTACTTGACACTTCAGGAGTGG
+
#'%(&)&%$%"$#)"+)'+%*'*+"%##$!!)(%%*"("!)#*$*!!+!##$#*+!!$)$*($*&%+(%&#*#)'(&%(('+%$%'&&)")+'%+!)+(&%((%"''$!"()##$!!%#*"((&)%&%*#(%!$%((("'!(*&'+!)$)%(%+%')$"%!)&*'&())$()&(*+"$$")&#&+(*&*("!&(&+!(%$'&+'$')!%%*%#$&*)'!+'((##"'%%!$&*'$%'%'"+&)!*)&&$*")'*'$(##!&!((#+*'''$*%#(()%+'%+&)'!'+#%"+*)+&'$'(($#&')!#**+!++!$$%%#($"((*(+$!!'##%++#+)(#%!")&+(+#"'#&!("($)$%(+*#*!)&*)&!!"!!(+&!+#)+!$'&#'+&(*(!!!)"&#$%)())#)*!"*'&!*("+!$!($(%&%#)**"))""%+*"&%)&*$+%&%$!#!"%*'+("&'$&!*"#**!##$+""$%($)&(!)#%#%%#+&")"#"*$*)$*(#('#+%'&!'*)*%$*(*$!$#%)*&(#&%*(&'&+$"#%+'*"!""+))+&&))##!(''")+'*+*#+#)(('&+(%)!#)#'$#$#"'('&"#'*#%!'#&"(#$+'+)"$'#$#%'#)(")*%(+!&$+$%$++&''+("*"$+($'!$!*)!'!)"$()&%$#&')!+&#&&$#*(")"%"((&''#!%*($("**)#&""'*'%$%'+((((+"$*'(*'"*#&"($)'$%#%%!+"("$*"&!%!$*$)"*!+!#!%"+*'&'%%!(*!*!#$*))#!*)!#&&$*!!%")$(*#)"%(*'!%$!+%$&*&#($(!("#))'"$)&$*"!#*+$#++&)(%(('++$%)$$$*!"%
@r4903
TCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGNACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTNAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACNACAGAGGCC
+
$.'1'$>E%?.F6"G;006:0(=9%;D7-D$<E&'@C=D>$)9%?EH!)3034D8H*B*$1G="A8)A0B+@?'5,929?FB@41E>.-060G<(@7+?6-%,*49;<H<!@(/+A9G'+E>F'G'"!@G%''06-/9<E:$4<#"1:/;7:DD69?7;@4(;/:'09)?0<0'@<E9)<C>0FG5D@'/E'(01(8F:!<;*04CF13FF,-*72?<:2B4-5H)+0)$+8
@r4904
GCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACCACATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGNAAGCTCTTGTCGGTTACGCCCTCCGGCTGG
+
.83,31D&*4"7'&D1?H=H5#@.&HH)63))>H4*>.26B*7)65/&8#"'",).$D%#92$#4H7:?2/-.6C,&!,(+2>:>.=(9=3)&3);%@7*F18D6F/-'G5D+4/*+=$>$8C0(D9:C70'=D;#G-2)&3')15#%-"G:=(6+@C'@8-E5C>)9!3E&;:*#?3BE1$,1?*2)0F;$>*A2@59(?F3B'.'.(9C2B!=$&2=5,6":6.--)E1-H8#*9E@C&5HD2"8C@$50-5F<2,>2(->1
@r4905
CTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAG
+
-D&@-30F/:E-A2H.-87EF5D:+G#H&D&A.9:1HB?6&&+9C9"76;%B8'B60'C#0')DH6/H@@'+GB(F:3<.#'8:8@(<3:.')0-32?67@#F%B9%7++&027(;FE.1$8C,'<'@A2)1(
@r4906
CGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTNATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCNAGTCGAACTCACACACAACACCATATGCATT
+
GF5A.@H;>'?497;E1FD4:?631:=,&G6.*%D:@A&(:<F9CB/4FG=9-2;%77)B7B#*3!39"FGG8>3!9AD.=AE;94:>CE44>(66%"+8@)/"<B;>&.+9:7F#3.A5%G1"!'F(3)0G0957,>+58;(5@'081>@;G692,8CD=.$3F./G5!52F8*),=B?'F=?-1%90E
@r4907
GATAGTCTGGCGTAACTATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTNCCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATNGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTCAGAACTTTAGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAAGGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGNTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTNTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAACTGTCTTGNTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGANGTAAAATAGTCAACACGCAC
+
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
@r4908
GGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTTCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACG
+
/<4@?EF=-2#E$F7+DD5#F9>HC.2/9HC,*H65#9:1=%F.9),+-&.#)F;!4',9".5:!G8)41<0AC%=2@#2>7+269*1-@>3E,B97#?0G"?8A7@<,-*6<$%?"%#A9:%="D93<:$G9G.>29(+;A6(&:>&97A-B>&>C/.94)&5E@,?@,#,*79EGE3D+$@.":#@6+*-4GG+8B'A$
@r4909
GATTTTTTCCGTCCTCAGCGTACCGTTTATCGTACAGTTTTAAGCTATCGTCACATTACTGAGCGTCCCGAAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAG
+
5)%(DCC#&3''>/<G/'64E%:@F>!%'$)8;/8#:1'>E*A;E,'4(B<2*24"'0F*"9<%%&$2/'9$B;=:D-,C49=$?;++'.1//208G63;:-C2;".0C$."!*F"*
@r4910
GTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACG
+
=F2$!*8$BF8E#'=;<(>#D0:6AH79<"='E=,<?1+1'=DA/;?-89H#;'D03)A#'=1-
@r4911
TAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCNCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATAGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTNGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTNTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGG
+
+78<E1-($A86.'E!)7C@9H*3(FF&EA>A0,G@*=+H<&'3('&E<9D=":454A27-=1*9>"-)>!**B+4$$/.*A%BB#&F>,D-/<*%D'0D*2=*B5B2:6&3%,<EF*7,00#>+3$+*?<8(689),6;B':!,>.D+'!C50CD-AG9C;1;<7A!;298)/59"-@%55+G5?,<1/9$G:9--H16F(,=*/"&F2;CG%4>>8%?AA&0:+3&)0>41::+&37)A%&B&%:?901%A3B326A@:8;C@<',G/2?#-*$-+56B+
@r4912
TGGCGGNTNCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCNGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGNATNGTTCACCTCTCACTNTTTTATAATAAAACGCCCGTNCCCGGACGAACCTCTNTAACACAGTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGNAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATNGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCNCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGANTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCNAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCNCACTGCGGATATAAAAGTAATAATCATGGCCCGGTNTGATATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCNGTCTGATATCCTCAATCTGCTTTTCCGAGAANCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGACGGATCGCCCTCCCCACGCNTTTACCGACCGGACTGTCAGCCTGTAGTTNCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGNTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCNGGCGGCGTGACACCATTCACCGTGCCACTCTGTTTGCCGTCAAAGTNCGCCCCGTTATCCACGATGGCCTCTTTTTNCGGCACATGCTGCACGGCGGTGATGGCATACGTTCCGTCGTCGTTCTCACGGATACTCACGCAGCGGGACAGT
+
'!#&&)&*#+!#++)($&$&"+#&(!+%&%%*')+!##%("**!&!&)#(*!+#!!"'*%%""+$"+&$*+$)#)(&(*'%*+$"%++#$)++(+#(&#('*+#"%)'+!$%('&%$(#*&%)*))"'*"%'$+)%(')#"$'#*)*(++&#'*+*"'"*!+&"(#)($*"'!&*!$%#!!*+%)"''+!*$)%!##+(&*($()($")%$""(*$$(#&"%*#!(!'&")$%)"('++()%#%(%#(!*"%%'$)%!*&)($$%$!(%""'!+&)*%$*%(*#&''+%+)+#+#+$''!"+!$%&*&)%)%#$!)+!!&*)'(+')!"$*!"+*"&&&#"$#$()+'!++"&"++(""#*+#%'*$!%*("*%$+%*+&(*"!#&'$")$%%#*(')$%)!!"%"'(#$"**%')##*$#&$##"''$#$&))+%))#(*)%((+"+##&(%'%'$*$)()!!+$'#"&*%!$+"+"#&&!&*%&$)%%'&$*%'+&'%(('&+!(!""#&()%!()&%"(*+*+&&(")'#&*%($*!*!%#!(#*%"*+!*)')!#'#'!&+'&")+)'&#++!!))#%+%$($"$$&"%'*%+&"(+#+")*(*('!!!')$'&*%)+(%#!)+#$)!'&'+"#'+*'++"*+'(*%!$+&$#"!%&##&&+(*##&(()"'#&)!+&)+$$%(("$&!""')'++#$'(%%)%)"%%$(&%%*'&$"#*!!$(#"+&"(*%$#*!'&%#%(%%%"!*)%&"+$"&'&+%(#'("%*&%&#!'(($+!%&%#)&%+)(*)'!!"!(*!$%#%%&%&'*!#("%&%*'*%*#+%!%'()+$+##*$!*#(!)+!!)('"''&("%#$#''%(+$$")##$*)"#'"%'*$**$)*'"#("!+'&+#%%$)'%")")*&!+%'!!$%&**""*$#"'+%$(%''!%%$'("+*$)#+"#")!(!*$&)##&)+!#++&"%%(')'&'"!(!&%'%&&'**&')$###+"%(%$+&&)))++$%#+"$$%"&$+#!'+!)'$*#((#%%()*$)(&#(!)*)'*(%*#(&'!('!#&)'!"&)""#&)&)+'"!%"(*+"&*'&#!(&%!"+%&($!%!#')$'&"+++$!!!&'*+!)''"!&+!(((%("*()%+(')"+"#%()(&$"'+!!#&$)+)$(&(%+(##%*!+$%)!("+'''&(*("*!*++*!%%""'&*'%"#&#$%)*!'#**'))&!)&++"#$$+%$&('+)%+'&*%$&+"%&*)++$%(*)$$$')''#"($!&#&!&'$""!!!*$$#()"'$!)!')!+(#&$$&$"$(##)%$'##$!$#(&%&'*%!!!#&*!%(#((*%$+)'#(#*(($'"#*!!+%*&*)(*!+!'&$'%+(&&$&%(!)*#$'&&*(%*"**)*(!*&!!&"#($$(('+$"#&!!("""%'$&$##$*&"#'%+"($(&*)(%+%&$)"'++*)")$''*%)&!+"((+)*$)+$%#%"+(*)**%*!)#)"#&*$#%))"#%$%(%!*)%*"'*(('$&*)'%%(%&$(&"%$(+%!#"#+&#!+''"##+'+!!#+$&#&!$%!"%"+()'$$!!!%$#&+%''%*'+#&'($#&#)'!&)!*))('#"*')&*"&%&%*#!*"$*!!$+$$(#"++'$!'&$#*($)"!#"'&&)&!"#$$#&(&%%(#$"%*%+#"!&("#'*"*(&)"'+#!#)##%%&)%)'%)"))%*)+''$*$"($#$&)''!#%+(*+)"%(%*(*$)+)*#*!*%$"&"#")+)*$)"''(#%!)&#"('((##!%'#!'+)&+!(+))#+#)"#(*"#%#+&!#%!#!"%(!(%'$#"*!)#%!!#*'#$+**
@r4913
GAAATAATCCCGTTCAGAGGTGTCTGCNAGTCGGGGGGAGGATGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTT
+
(#?))5=3->65/!156@C=2G44'"@&!B>@*"/E#H'=.0!0;4*@?8&#>2'9((1.+=/(-;*H8">A,?(>(4;23BC,70$HB,98H"AE&C?
@r4914
CCCCAAGGTATTCAANAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCNGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGT
+
&:;:.G4&EH@E8A)=#4?0+=/7G$)CHE).+.H3DB?3%>=BD6H6%9C3+@,";803F.6@+G"9F*(!H1#@B&:>$/@1*0@#0,F@:6,0!&:)&H*0+"+
@r4915
ATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACANCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAANTACTGATCGCACTTTATCGTTTTGCATCTTAATGCNGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATATAATAATTCGT
+
(2(6F589/&+#47>:>F+!=+>7"3*#0)%4%BF@"69B6.)A-(%:3%F"6;!F0H-%+$A#(>(39?;FG+F<<=%70">(1GCD*9=G#1&%?.;'2B9&<E1!&GHF>?!17*E<*3)!55A&DF!G222$,?4<+!?:D=);E?E+4;*30$9F>+*?8@@3&#5A:,>".0+/F5%>9,5=@%0"C;9E1>9,C:2>+26BE5A,4*9,=G"-&CA<G$#4=&H?&)4(78(42@$3G#6+,&('&25%*%CG@E*9?F,8D.D,=*060!3>$$.''.E521=6)%)!=E4
@r4916
CATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATNTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGNCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCA
+
+*&+)*##$&'+!*'*%'&#*$#*'$$'"'$&)*+*)'(+"%+##&&%&!*+%$%#'#"&$*!#&!!#)*"*%"%'+$%++%+)+)!!)#*((#'$!"!%"'**$%'"++"%(!#+"'("%(**+%+(*++!$%$*#%+%#)'"+$+%"*+#+"%)+)(%(#!)'&!$"#*
@r4917
TTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCCGTCCGGCAAAGTTACCTGTNCCGAAGTTGAGTGTTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAANGAGCTCAGAACTCCATNTGGATT
+
,0"$08&-2(D?%C?G!(F#'@632=5"B'G#+0(2E6!"4:;,4AC5?)(.+)/9%6(>7(<$DH0@",>0>"F:5?<2%$H03?='B(!=4$'5,=3"!&(6%<713D'<2%1)-80E*(H0D:%5#(?&!/+/<'"!G#AD1#&5,8B9
@r4918
CGATCCTGAATGNAATAAGCGTTAATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCTGGGCTGCTTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAA
+
$/BB!.)B?%B*56B6<;4';8?3"&+C3?+4"A<6$+4H7#F$</#2:A<311;=&7/6?(2(=*-<%CD#@2D?:)2E&9"?'D)67,$71"5>(ECD(?!=@*F3)HG"9:GFBD@"$0H,E721'HH&9B%H5-1(6<2),$<8%9%':)D
@r4919
CAAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGCGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTA
+
)2B/E<84".-;BC=3H00=92@BG33!E!9&+?G$>D2(FF)+E>?@=AD9D#8/5+HDEC4*0DA9H:+BE-61&$-=E;$D"9FE/98-(>7,6.)%0-.'C=(>%(02@1*"$<'-<)("4H9;2&6'/"!0B*,4B(9=@H3@./%76D%3-F8$F;F7(FF&F(9140*1=,>'1./"4A>,@>>(8G#9,+<B0(FA2:%%1!A(&2=A9",.47H1()7.3,C$H+HD%7F6B'$=BD=3-F66"AE@C0$&F";0A@05(@7A5C.A9?<9(#@54<;%<--(2D#%$*-!<!2:/E3;(6B8B<7?:@?C#B'3-C-3
@r4920
TTGGTTNCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTNTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGNCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGANGTCTTAGCCACCGGATATCCCACAGGTGAGCCGNGTAGTTGAAGGTTTTTACGTCCGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGNTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGATGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAA
+
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
@r4921
ACCGTATACAACCGGAATGTTGACCTTGCCTGCANCAACGCCGTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGATGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCG
+
001$E@;+4F"#$=#2B278:/DE165D:4ADG015-*FD%"42ED3E'32G9032!>(47$778!=8'EE3:9H*C6+B+7<2C:?8GBG*2"5(AH<4E8,,)1<&@!$*&1/#E#4&DH1A97#0<&91B*@(.**@..58+87+/-/E-A$+8?%?9'&@59"/3!-&!:+%;4940*/509&<D#F0B-"ED(%B"4E&7A!68-<':E820$#><+)(=.#=BA#69=6;5(679AAH>/:*31=3@:)-,6,5;0%7,3!E*),@BH?@A$=$!+)B4@(&:E-*!7B)'&>?H/4.7:"=C,"40>*?-.#1C8,6>-H20<'B6!=&5F5E'8%()2';*3!D5+:0
@r4922
GAANCNCTCTANNTTNTGNNAAGNTCCNTNTCGTGNNCGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCANACTCACAACAATGAGTGGCANATATACCCTGGTGGTTCACGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTTCGCTGCTGGCGNGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGNAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGNATGAAAACGCCCANCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCANCTTTACCCGTGGCAATGCCCGCGCAGACGATCTGTTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGG
+
(#$!%"&')$!'!&)"'%##*&%!&)$$$!&($*!&!"(++%)"$*!%'#%#&&+&%+%&#"##!$*!')++"%(&'"(!&#($)%*%$*""%#!"%##(#'("!&()&'!)&#+#")&)"#+%(#&!!+*("$+)&(!*%!""'+$&*("#%!"&%&%"")"())!'*)"#&'"*!+'($&+&"!)&("'!*&"!!"%")$)$!**&+'*%#+%*&$''+%#"$%"%!%%)*&%''$"&""%#%#%"!+#%(''(+)%'#!!('%(#&++$+*#()%("'**'"&%)(!++)+"'#(**"*$'$($(''*!!*$(+!*"'%!%"'#'(&%"&$''&$*)#*''")&#++"$%!")+%$#'("+'!""!(%%')##)&($$#($##'&"+!+%++%!$!%!+$(&(('#)&!'%&%$#"$#(+*(&'('(%)!)'(+%&&)!+&!##"$#)$*$"!""'("+$$($"+&&'!+$*'+(!$(+"+%)*'!&#()(*$&!#)"#&#(#$$')+''$'*)%&+*'!##)#'("$'"%'()$*#)!$+&$)"$'(+"%&#+(+%)*!+''))%%$%$**#$!!&$%*((+%#)!(+*%'%$+%%+&'(&$'%*)#))!$")%(%#$%**(&#*"(#))+$!%($()&#)((*+$+")!'#+"*(+('$"&%*)&*)*$'**!#"))$)'+"(%!%)$!'!*'(!'&%&")"+)(%+'!+*))"'"!+*+)!%!'!"!('"!+$$%+$&'%*$'!(*#*"$%&)%((&$+#+$(!''"'*!%"'"$'#!*"***$(!+')"&"()$$#
@r4923
TGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTT
+
-A=<#D)1,?DBG6-H'?4*@9@@+43H1H.;(6>?C#A+A30,3#=)06'"'%E>/>1E$?9-))0?1$H.C+&*(A:&3,5(#14'20=1)*B3"G$.@5(4;@-HG
@r4924
CCTTAAGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATNACTTAGAGGGGTAACTCTTTCAGAAANTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCGNATNTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTNACTATACCTTTTGAGGTGACGGTTAATNCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACANCAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGCATCCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACNATACTTTTATATTGGACTAAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAAGTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTT
+
*+"!!+&$)&"$+%&%!+*%!*%#&+(#&()#+#)(#(!%)"(#&$!""(#'"%"#*#*"!"$!%++%')'&*$%'!'#*%(&*')$+"&%("$#*('%'&"+&"(%!+!)*"##+"+"'&#$!+'"$&#!"*)#%$)&$"#&%$!&+(!"""$!#+)%$$$*%'""%()($!*''(!%)&"))*'$')'(++""')'$))()%""!""($*&+&'!$''$"*)(''(&%%&'&'*+('$)*%$&#!*#$$#$($()$("$&%%%"#&$#%%%$!&$%&#""*#$(+#*&"*&)"#)"&%#$'&"#%!#+#%$#*#!!#$$%&*+(&&&"&#(('#"%+#$(%*#''*%%'(!#+'**)%!%%(+&'()!"*&++&#*+$"+)*(#!%)%+$$!))%*!)$%*#)((+'+)+#+##)*!""$&$*('&%#(+'&'+$*+((("("!%#!"&((%$)#&##$$)"+%%''!$"!"'%*%%"$'*+($($))"+))$"))(%!"($"&"*&"&%#')*&%&"!$"()#$%##$$*+#%#(*(%*!$(&(*$)'((*&')$)'#$%#*"+!$$++")&!%#$##"(*&'"%)*)"'&!)*#!")+*)%'#'**&"#%+&*&*+'"$!$'(!)+("!!)+%*$%%(!&%)+(%+*!&$$&!!*#!!"&'+)%+%%"!+)*$$!*'"#+*$$+$%"(!"#)#"!$(**!($(&'()#%*&$*!!'")'+&()$)*$!*+')!'%(''%(&*"#&$$*(*!"($'!$'+!#%&"%%#!'($$("'!!#*+!#$+**+*"'!(+*!
@r4925
GCGATCAACAAGGCCATTCATGCAGGCCGAAAGATNTTTTTAACTATAAACGATGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTANCNAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACANCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTTAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGTGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGCATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACGCCCNGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCNAATATNCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTNTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAACCACCGATACTCAACTNAGCGAGATTACAAAGTTACCNGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTGGCGAATCCTCTGACCAGCCAGAAAACGANCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGG
+
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
@r4926
TCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGA
+
"C$;20!2*9*6,%EC8%30H'@=(6>2B"'5'%CD$&<-E*-C.)9$(($:2C$%/"$/@@%E,))-@=CDA22G5?=&*F!.;#*19'E9!003E;C1GG%'%:+>"?8+.@>18H=531436F0'HD3,A79"A#7F::<!H(!4<,;C3=HB'C;@5$/C.6DC?+3D$@'(?:D1*5<'A==F-##95!C/0;B6465#,:B>>+D$>#/"%8F9+F0+DG>!*(@=<&72A91/%0(A2(>>H-6%275:,;#H3/?.1?%;'<H%0?#&HB@=;&)7$:%!'--,*3D.>#C&!>@
@r4927
NCGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACGGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTANCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCANCGGAACAGCACACACATGTCGCGGTGGCTACGTCCGTCACGTTCACGCAT
+
#D'!0$01!)F@'B9E,6*,5>08G4!2C2*9DC6/5@2A3):$?6)5)?G&);?#C5%D@;3690%->5()3=%%=E0='0@0(#-B.9B9E,''H8E,E?9;*:<?<-E)5?,DD,H,.2)DD0"9437);$.;+0!5+5)12$8%;;;3#6$C;#7#6D:0F=;4BH)0H--).*$,:)8*0A5)<0;;":#%?.)"#,F!)$B9?%?B%6<B/46:-@;?'F0C"++70<7':':(#,%,(/;E#D"5B3$A398+78;@6H($?#,)/(<."4+C32D.$@@?0'.(&F:DC=@:E;1:5B+2.1/<?5-(5$=E&/1#D"G$)<+#(/>C#;86)*?);8;+=0)4?6:+;&'B-D4.&<H-3)C34)0:!-$,;)E6;<(/<"">
@r4928
TATCCAGAATCGCGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGANAGGCGTGTCCTGCCCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCATGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTC
+
?7:H4:<)<667659&1-&$C%&@A8#-$&#@>0/?)?B%B'8<:H6#/8B>*&&06B$CH%0C,*/*5&AC$2F(D$*1E#@9971+4H"B+2C8%(/E//A?@?.(*7/$B>&62DA?--2+3=DA*2@H7F>0%?5BG<#5.7:-$6.1"*DGD49?.3?FD0@&5)#A-)8;D7E(6%-:E5:53<98%1F-5)<HAFF+@EC5800==*C5<?F.8$8%<>272%-5)
@r4929
GAATGACTATTCCTTTGTTACAATGTTTTATCTTNCTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCNCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCC
+
>=DH=)A$?%'&+<"HG6>/@*-/D<-2"%("*:A?CCG4=%:4!28BHG+*?,C$/5&@H=;07C<:EE0.,D02;=$'10*;C-883B&,3@*""H2*?-*)2<;,(D*";?"D0D4'3+F8-:/30:?#>C!2=$=AF/?@9-7.'??009,%;&G#F@4!7!<.G<,$@.9!86E4%A6"!1E>HF$E,)'7G$=/,)0!C08(#&C5H";9!;:5)9%@1:E/,H!=A/24-7D)F44EDCF".E-)D7&D#F;876&>;G50E&F
@r4930
CTTTCCTGATAAGCNGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGNAGTTTGATGGCATGGACTNNGAGCAGGACAATGAATCCTGTACATGCCNGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCA
+
-F79!H'.9F",H,8C&F;AC'?=A9@?6?D0"@+*--A4H:&22;?H0=0!0>5#H&<G,.2(+'2H=%E&=A6;%:D%78H)=-A/;'&7'E<C$";03>@+(5')/23B:&?62>4>G<!4?H(F!<><#(481'$?3)/D-@*;.5?E2)F$4.#G@G?9#(1,15,?)DF=3!G?C2%%E$%)'G=?<;EG0:87:3(8>G-=&>)B>=E!A1/1D;(5
@r4931
GATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAACCAGAGGTAAGGAGATCAAGAGTTACAGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGNGATTTATGCGAAATGAA
+
?&CD#@+B+)HC"36<2-86@D<%..!(8E;4#+>><'5<(A4"E@$10+GCF37G>;C+<A.E:%#&CB!*C,$&8**B:5/CD%H6(!2),#2(*A?DDD79D@"#<*2&>"?D*E'!+-7/++>(+#-0-%927"-41FC<:.?!G5+EF3=C%.0:C8A9G/56A-<6("C<=5:3)E#E)7;2*->D;%5&30=%/0-"F=65%--,A>,/B2><&*::$-$,&
@r4932
GTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCNGTGCGTCGGNCTGCGCACGCGTAAGTCGATGG
+
)A*)#4B4*9&)?>'A-@+>95C2#.9@6G1836-"!A3D>CB(&1,3354<B-CB5#?%F(?*1"$<&&#/-$D
@r4933
GCGTAATCATGGCCCTTCGGGGCCANTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCT
+
*&+()$(!+($*!##'"#"%!((!(*&###$)$'+#"&!%*&&!##&#)'!$'+$)*)!#"(+'"(&"+(%"&$+%$(!!!
@r4934
TGGANCTNACACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATT
+
"(%%#&&*!)*(%++"$'&$$$')(#""&+&""***%*!$&"#)()%%%!+"
@r4935
TGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTNTGTGCATACAGCCCCTCGTTTCTTATTTATCTCCTCAGCNAGCNGNTNTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCNCCTACCCGGATATTATCGTGAGGATGCCTCAACGCCATTGCTCCCCAAATACAAAACCAATTTCAGTCAGTGCCTCGTCAATTTTTTCGATGAACTCCGGCACGATCTCGTNAAAACTCG
+
23C>=#%@C.<1"*8-+*706;3")9'?>8,)8H6,;)2@7!"B4D3EEG)0)0G6!21C3:H<A!C<@"3F'04.8*!(%0B=GD&.!GF00)@?.34@=A;F/D8"1:F,9F8962CF/)&3E7(;>'B*G,!$!-4.D7C3;6,89,;AE:E7'2$(9&CH)73A2F*A>1@,EH42=""3!":).G:<!701F?$87=>.7>*?%E1C.02HE=+#;AHF@9=)-'*;F,$<3*EG+*%<F'H8;?DF!!@%&B=-,F>,5!48!5G7%*A7)6HE?;1('B2<8>(,&5D70<<+@5@$&G,+$E@2*96'=>12!7=C&61
@r4936
NACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTTAGCTGAATGGTGCAGTTCTGTA
+
1<5E**+4CE:##G%1#,&78&E1()2C));#8%842C."/!06(4%5A!@37+>1(:H0;/442
@r4937
GCTNCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAANACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGNAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTC
+
@6E78<-,4EA&=H+!)$H9G%<-6/A9*C7HB:"7#8H)09089E')$C#;/"2E**269>..@C88;3D")52,"=+9'+=>7%?!,D=*:##08=;<F/C97A(4HC>>6874=B:=F0@4DF;B12,&=?/H4+H,A63'-9'HBG+:35F*7%F2,0(55362/0=B(@9-C(DAH"?'E5B,=;.D;5'H3!+0,;<7.)7;%55A<"+::&13%$%5)/8:2<D6,:'5'$.B7,(<4/:)%@E#)9*F5*::A97#,%,E;,)&0D6,4<0:-E(B:976)G6/92/<B(;<G1<#'?D<6/1B:>&&7>#*F=:G"8('1/(4F<B*7G3F"5@*+%@9E@%;651+/5(3?6B)2,G.F6%<.?+"D3(*20EE0:,*1>"-<&61C,60>.<5!?($*0E?/6D7AD5*.%B6>F
@r4938
TTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATNAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATC
+
4.;,$*)5G()&HB$'70''*;&5!0837!!*.HF3.'#H'!&DG"7"/55;9FE4190#)9;))515?23)F:)<$(E)=+(:G4+9&$%3<H*=1419G?>9,!AB==(<3(,&?><11(*;(@'"F$0558*/AD-=/@".E4*(C".+?G0($;%.'-':09"!*G)198&).=>2969>.#+F&5C4<:+(H3B,7G;9A"88>!4%$6C2%D7B?H)H?=?).5*59735G>24?H*,0%(;=?,=E8-1%<$"'>7&*6('>!F78":60&+7)9!>H)DCC775F>:#>/'C0-$=%),F1=4!1.0+
@r4939
GCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCNGCAGCAAGTGGGGGACAGCAGAAGATCTGACCGCCGCAGAGTGGATGTTTGCCATGGTGAAGACTATCGCACCATCAG
+
5G'-"E/CB0/AD2921#7)9/,B(H27?)HF>6H(:6H6$0'A83EE"D.*@74<6&H+HB9!B%4'B9$,5+'$E)-7;&'*6<B,?$C;7&#03A798HF9D",AF8CD.%(2,4=27&'*/1$E
@r4940
ACGTAAAACCTTCGTAAACACGACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCNGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCA
+
/#"@C=%,#*/299+?87?&;5%.B.*<9;1;5;1730=,E<$DG9'<!:?!@8'!.6(8%EH2"-,,2B5@>:%<@=4B4*<B0E-%=%B)!2;<##2"62'+<=<;(1/7';#6E8C.E;+3&A+F&?&3>4%--BC7*5B>67<5)C4</<C(1:($=*>*)BC3>%-0$D"*33%G'+?:>;;@FF=D(+803?@:H*!8;5&1A"30D.=%*,C#&D<8=.4H'5=":2";D$*!
@r4941
NCNNCAGGTCNNGCACTNGACTTAGACTGNCCGATTTAGACCNNNNAANTNNNGAANNGCCGGCCNNCTGNCNNNGNNGNAACNNCNANAGNTNGGANNGCNNNGNTGANNTTCNNNGTNGGNATNACGCCNAATNNTNGTNTNNNNNGTNNNNANNNNGGCNNCNNANNGANGCNNGANNNCCNNCANTNNNNNGNGNNNCNANNAANAGTTNAACGGGNNTTAANATGNNNTCGNGCCNNAGTAAGNTNCAGNTNTTGAGGGGGGNCGNNCCNNNNTTNGNNNTGANTTC
+
"!""#"$#""#"$!$"#!##!$$!$$!$$#$#""##"$!!"$$!!$"$$"##$"!$#!$$$$!#""!#$$!!#"$!##$!"$"!$#"!$$#$$$$#!!!$$$!!##$""!#$#$#$"!#!"#"!$#####!#$$$""$!!!"$##""!$!"$!"$#$#!$"$"!#"!$#"##!$"##$$!#"$$#!!##$"!!""#!""!"#"!$!"!#$$""!#$$#"#!!$#"!"$!$"!#$!#"#"$!"$#$!!##"!!#"$!"$!$"!#!#$$$"!"!#!"#""###"$"!###""!"
@r4942
AATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCATGCNGCTNACCGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGATACCTGACGGCCAGCCATACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTNGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATNAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACGCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTTTCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCNGTCTGCTGGCGTTATCCTCCGTCACCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTT
+
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
@r4943
CTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATNGGCATCAGAGCTGATGAACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAAC
+
>/>0H;(76(8/AB'-/@"/G<924H,*=!)5D#160?AD;53+%!<3'47<E)#-*%#+65A1*9=;02%:<%*$6(?!18?<1B-&F/<+-'1-8<.)0(@@2E"
@r4944
GACGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTNTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATNATCTTCTTCNTCGTGCATCGAGCTATTCGCTCGCTCATCNGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGNTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCNTAGCCACCGGATATCCCACAGGTGANCCN
+
(!E&%:35@A6;>A?EC',3(=F>.B<3('D2?C5C;!(HF1=)8.$:"9=2D-(40<)-*,F+:CA0D/'D>$C'(G&997C=>0+4<59H1,;@5@9H$#D!$'5!:G@2G&>=.B5=-<@)B>;#B/9A#><"6H#G3'*#AH$D4"'*7,8<(-61=4H+(1,>C;F";,$/')80*79F.DB.(B43$64@2-@A729'@6>)D40+;=2C3%;8G'>:"#+&$A@9))'.D!H"AF&;G;:&2:32#F512.0"+-A37/%F3<.2-%)3051/">3+'H6"A3E/4*B%@E1&-H%;->>?4A42(0981%,*8+AB;<+1,$C(,G5"H11#&*A$GH+9<$<&/=*G+6=-=B>%&(5%;/6'F5C><5)7$"0(:*A=$%7*5):(&#6G;H;;05+##0.H;0F3;0-2!()5>/B=;G"&'.*-/>DC<;@:2C#E9:)-/8"'.7:;CBB=E7.H4C=;1H75.%"C"-9,
@r4945
TCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTNTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGNAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGACCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGNTTCACTTCATGCTTCGGCTT
+
/%=;1.);48+056('/G33&&@<6H:0AE7+62)2F@@8%39;'1.)1.:$AA5>*,@7!$2@>D"$D$93F%DB>4#>C-/AG)HE=5G4::C'90=46A8=,./@B:A89$%E+$1$78G<F5&/@D8@7C-?8C3=DBF>4'9#)1"!1B?<3%+C'@F6+1%29!&(<5'$#!($>6%-B@(87)9;D",FC+9:.=G;3B-'9E(HB2B37+A:<F'EB@:H-4:C9@FC&;8142G))D93'(59)?B>9ACF.D/G'2A:-<1$6F"6,9#5)8").;$BD-"5"%H$9H.96@>)!C67E';/769**+;-<?E-.5?2>ED2)C:D8#!.5%F=1'+>+#C%9@2'0:%3A%#?:H@7A>66!D(+12+)<?7E&/);=4:F'0<=F:!G87".$8%D.1-/,<!/"H*6'0@&>.>*#68;,1G5,E<&&AC*.!4$8#.*F7=)!&@G3:F98)/;3AH.31(?A8.?#.#-E2;;@''?)6FG,
@r4946
NNNTNGTNANGTCAATCCCGCCAGTANCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCAT
+
#"%&"*%%!+'%'""!)!&**('(!*'(*!#*&"&'+!($*#'&%$!*%'#(%+*#!*)'$$&(%'+&"$)$!!"$%"%+()'!*)&$&+$#*(&"
@r4947
ATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGNAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCACGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTA
+
.C$28+6<*-AD?/)1)<;!A,,%.<6?+0/F>.:(@30:@B%':%'-09;H?&C4(/>D+3+%DH0"F;$>6$;2?F4G&FB21ED):21%3$&0E237>1>1/,(3%/)@%,A:"0-48!35@GF/0>.A2:5@B<66A-<H2D<3D@?>C9(++).,FE&+'.,196E@5G#1)4<2.6<@4//56A31,A3G#H@'9!F&'7CH358/4<B$A#5(?3():1>,2;-1+%%>/#@.:,B";8'8'B:4@3CD03"F?C$5=9(#(89A$81#.,H!4@0.=:,A$5/56$'-F'H,=<2E6#6AD"4D/*511+3-$2=0)G@&F(B>B4F'>&
@r4948
CATTGCACCGNTTGACAGGTAACTTTGTAATCTCNCTAAGTTGAGAATC
+
D/&HDHCH0=&3:H65".$H:F%E%/-$(#$G.@:G*<H?)!/EFE-)E
@r4949
TTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGG
+
)&%51BD1:%A513#C:<A28:)>!':>B=(ED!D!6G!:$H73A&>8"B"!#D955.*?DG):7A/%5E/FE%$&H8H'?'6+A$
@r4950
AACACCAACAGGGGAGTTACCACTNCCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACNTAATCCGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCGAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACNCGGCTCACCTGTGGGTTGTCCGGTGGCTAAGACGTCGNGCGAGGAAAACAAGG
+
5/&D)3;:&!70760:)@=B&-EEG8)9>+<<F>H>,4$"%*:45;#2C/F'#;.#"+7E7+$.AD=?3@4B*-$6C32FA-926"EH:(E!*=C!/G*G,0.7C?105G+B)-#'E2=.22!<0BCHG#6/#)*A38:<9D'4:3:>=*F!?@738:6!"7;84.>F74##?B*?6(-7?9=+<EF-GAFC9:=&FBF70!5'44F7/!9=1"$&.@A*-)&<>
@r4951
GTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTCCAGTGGCCTTTGCTGATGCCGCTTCTGCGNCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGNTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATNCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACAACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCNTCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCNGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGTAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTNAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCNGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCTGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAGAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCNAATCAGAATTTATAACCGACCCCAACGATNAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCNTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATANACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGNCGAACCCCAGGGAAGCCATCACCCCCACACTGT
+
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
@r4952
GTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACANAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCANAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATNACAACACGCTGATGGCGGCGGCGAAAAAGAATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGNGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAG
+
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
@r4953
AGCTGNAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCTGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGNGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACTG
+
D(!EF;4"9$=!@A>F3H>/9@<GH7<<=0,,F%0*=(-525C%G,%>/&7*?$/>C0.)".1H%.1.A.-$%*&36@,@F+*85E)D!!@9@!<!-8%%.#1C@D&G1@H*C;9BC38H?97BH49EF<((891,97"/:7:;C-07G)13.C#2H'1)+98E>21$-)#8AF7!</4$2.H+=7'<61F&HD7D?39<$7"7*(,7=24:0H03+B1"B)CB'6BC#.A+8@:?:/&#E>":36=8F7EF2D1C#>"&8A..<D;$?=BH*F&"/7*?!9:H$>/(5E-8.2:>)=#>
@r4954
TGAAGCCATAGGCATTTGTTATTTTGGCTNTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATTAATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGA
+
-':&-!>$'"3>@E-*:9-D>:4&3>!(*"#,65'=!8;%C3.?"EFHH08.&(402C#5!54#:#)':;62('$B<(,5?E(6H8,<C5*!/43=#H&#,:*E:E%$%%4':27$FB!410AFCF7>9*-?/B)'/
@r4955
GATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGNNGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCAACTGGACCTATCGCGGTGACGAGTGCGGTTATANCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTTCATTANCAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCATCGANTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGNTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCNGGTCTGCCGGGG
+
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
@r4956
GCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAANAGAGTTACNGCAGTTATANATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTTTTTCTCATNTAATAATAGATGANTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTANACCAATGTTTAACATACTTTCATTTGTAATAAA
+
?;)/(?284?H%<>/645!2%(.,6F81>4"D<72,;=D5FCG/9<A5$,&%8@<E$-;+;'.><-E@0(=?=>G!6EGC3C;+@CE!:+*9*06)(*(,BG99H!7,B(H!=#3.)E>=B+08G,9H9&"#DE?3:/C6FF$8D>$D29*4/C0"62&*;02.?%C9E(8B0'(A2E81@"2'+91<E.*(A2@"0@>A.B*A@7#H4BA)@<3$?A05=7)5C3;@''!FG$&=H;A0"1-<%
@r4957
TGCCCGGTGTACNGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTG
+
C:<F4!C$(*;(#-.3(G0B1DA,7D@6!/DF,>GAE@55G)>G6%-F2126$E?9D(*1#)>:E"./A)*.=-4"%8%%F0*7-#)#./!1&.92C$+5+5B/1!D%<F.#7$?"?@5DC*4"!F<!8FG:A0#'=@>.')C(8#(?.EAG31;2,373:;&1!
@r4958
CGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCNGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTNCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGC
+
;7-48/B4=55<1H1/?38=H+F$<4%F>;B<!E-+8&097C<,+<2"F.:'?'#:8G'#<6/DA$@+%(A"F&7=&!)*+90=)!#?>"BH$GFA123G&5>.+95;!G4'->BH36$8$30.A!'*8C?=E$1(-.7D'%7C8=H??1;!"5G+&%7D'++?;C??G:@.?,:9)0,),H:>0*4H,89;;7A,-G8&/>>9411?G<@-:%2-=$;(&7A;D8)@);?7BF*B30
@r4959
CTGTTGAATAGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCAATTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCNTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAACCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTNGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAA
+
*$&'0,<"CD(6)""%1!.F34),FG)773/$F!298"#4)A)&=@"+F:,+7!(H"C%.5)3G&7G2,+;;#.611':4<H)8#9+:BG<2$-&7-,.4>,7!B!)F<G/2EC)?A/:&**45G*07.G/BF:%A?7C)%F2418?&6+-%9$D40(/+4H'51F6*">576$#/.*3D/2>8%+<F/&51F#684$2,'#GH8H:>8:(+>!(70('!9EC8)'*E/3/?:-C3%)*C&9,;BD>HE%2=BF#/7<&+5"-;;&)#-%)$$H*.//0.>>+4<+4!;C3&*@7?%$<7<<!-8?*G22:A06E1B&"''3DB(D$E=H.A94#44#,D/F"(<;@6'A"".4>3#&4'0B#;CGE""0--*73H91H>A&G-H7&E;147BB47<?5'$47!/7'9@29#*%'B&#EE;"H((E<C?27(/5,%@.:=01H,3)*H"EE'D489!7,=AG%D/!
@r4960
TGTTCAGGGGCATTATTCNCCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCNCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGAT
+
"?3C%B6,1$;?>>EC>$67#%?3(G>6B?))09<+.C&37%G/8:9A$8*,&">6#BBE6@0--DH;@"B9%#"+D=;$7.BFH>3:56%D#02::EH#)2/<*'-B->*B>B4#G"$$%@+GD9!8:=(A6B"9B9"EEF?G69B8?4H3D4$16-D"
@r4961
GCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGG
+
/H!1=78<3:=4HE3>48,%7FG*-3-HBBC0430<:+(>
@r4962
CGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTCTTTCGCTTACGTGGCATGCTGGACACCGGCT
+
!C?2=5EC7<@/@5&(/;=HB.<D$05F/@(9??&;=+:F#-DG&EE#"?FBH*6"#$7#C;%;6"A@DC.4B"2F/;3"01
@r4963
NNCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGACCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGNGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCAACTGATGCCGTTAANGATTTGNTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCNGCAGGNCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGAC
+
$#+*#'(%**)#'%)$#'$(#*#(''$&$$#%&*)*$*''$)%+$(%++)')!)$#"#&(!)((*%))"#)*+)!+('#%$+%+&+)"+++%+!!%(&"&%$#'")+'*%&(&""!"$$%%+''#"##$%%'$"$&!))!#"')+"#"*&#&*')&%)"$%"%!***!"!")&%$(%!!#$#%!*"&&"!%+!'!#$*"*)*'#%'$%"#$**$)*&("!&**%)"*)'$$)$!'$)&#$))+&+(*(*(('((&(")()*"#!+)!+$'##('(!%%(%&&*&'()!"$'*"#+*$!)#")&%*!'%('#+'(((*#)))$%'&!"'&!!)&"%())*$$++$$!('&'*%+)#!$$#)%('!"'#&(($&$)%%(('"+'+#$'+!+*!)&*+(+$%+
@r4964
AAGGAANAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCNTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAA
+
G$31E%=;0#4@6H71/@-H:&@2>13)%>;%=(&5;F30&=F%47B7*)ECB>!-;B4)!2D8'2>9'!G:=D(!558,AF8BBE5-%16AD<0F(!@FC1&B7?%B.FA";5.#7@)$<$()9'.4F/9!=!5=8*"84,8!=HB,;)C;/"935H7$"9>;'-4-0"69'G*/;/B85/:?=DC''E4!GE37,-7941%"%738"%;=@/#)#0)"F193*=/2D@H)BB9CB;&;F)/*##8=5482</:G;*':<C2<%>5=!E"/<-E?DF2,AAD=$:%-9
@r4965
AAACNTCNCAACTCGTGAAAGGTAGGCGGATCCCCNTCGAAGNAAAGACCTGATGCTTTTCGTGCGCGCATGAAATACCTCTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATNCAANTATGGTTTCTCCGCCAAGAATCTCTTNGCATTTATCAAGTGTTTCCTTCGTTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATC
+
'#'&""$)#&+%$")+'"("%"&$"*#$+%($((!#+#*%'*"+)*)$(%'*'(''++"$'&!#$%$"(!$'(%'*#!)&('!*!*#)"%%(((!!&")*$"$'$$!)()'$*$*%*#$+#&&&#$&%!&)$%'*$*")++!!$++!$'("%%($"(%')&#!%$")"(*"'"!'*)))"("*(*#'$!$#$&*#*#!##'"$)#'%)+("(#(##$""()#!#*!*#))%%($&)+"'&"&'#%%!++"
@r4966
AGTACCCTGTTTTTTCTNATGCTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCNTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCNTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAACCTTCCTGACGGAATGTTAATTCTCNTTGACCCTGAGCAGGCTTTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACNACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGNCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAAT
+
+*(H/5G<A*#71-/"<48H>+&*@63%F&)F'0)=7D</.<%2F%HF1-E@*,:*?AH.8;A);=-=*9(</*9;/(/;@.A0F&#8D$A6,.9?#0F?B#@#'5:7>31D$!'1#-)*04(>(3A*??-3;16*!0'9'F$C3=F(AF;6<C;->7&/6/)'5FG"5=3/7%0,+$/G,;)158!,2;.31@B:+/C4)',8>58:)A/0=?5>7:-0(.("=&>1+F3*EE2"B'$F#H*:)&:<+D75+9,4H>:E13"*61$$-',D&D6B"=H&)49CH22#G%'*H*7<=A?($$614=((9>@#472AF'?H)-E>2CB07<>2,;>:A/!(:2%HB#>$H/26*:F'9<H%<0-3-#$,!+%D#598;<GEAE(:!4C@%=!9H:4C,;;281FH5%3#<*<+$41*@<3$&9C7A<,=A0F?7**G%8-BCE20/DD)A&6#,/<'!BD941
@r4967
CGGGAGACACTGCAGTCCCGGAAGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTATGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTANCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGNAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACC
+
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
@r4968
CAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCG
+
G3/EBH#;+&9/EDFF$%EH/5=",5B<+%/?G&05>C0E>'?4HG+6+F.7?#G/&"'=7B-F)-%>!2'?!C1"$E$#F8/!;?D!$(%&)H=24.E-8!+
@r4969
TGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAANTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCNACGTGCTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTCGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTNTGGAGTGCCATATTTCTTTACCAT
+
4?:-H31-&8)A-EHF9+,;/=&,,B42E->*=:(3?#;+,*F*<!A3(2%>#F0#BB2<B'>?"=<&2+@/("G62%@*!#)E+13@)*"$?$0';?;F#(H(#*HG!3<'&!81B:*EG=&5F-6&2%:50*:>(C.:??%%9&39:9>">-D410E4C&5%'8D.CCE.@,B#6(0H6CE10H$A)H8D:;?)B$-,$/@"&*>@,="/>!D!?/'2*&%(*8F.D?+(/
@r4970
TGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTNTCAATGGTGGCGGCATACATCGCCTTCACTATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGA
+
6E..'<*2B6=,F#?@+2%"*>.H$%"C?'2A"C*D3*&BAB)!.7.+D,E==GH!AB3:GH87@=-E90G(?#D-+9$HFC<9&(3E<!*.6/&C0(FC"?F/?7?93;+;/(5*:,C"3-3&E;!F$H35!H@F0+0?@81=-."C0)G47:A'$!804"=02*;<$*%/?;"@3%-=:D."+7&!BC8E1+!<"0./@:%<.(*">91=$$<3#-)<0@H>>82%("&(9/B>C$6F#/,<105>9?@,5)6,(;@,+&%9A!#?*6A>9)EF2FC"B$E'&371(<6G46EB6?0E(H-:(;1-$327;,;:)
@r4971
GGNATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAACTAAGCACTTACTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTTTGGCCAAATCGATTAGCCGACATNGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGANATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTGAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGAGTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATNCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGNTTAAAATCACTAGGCGATCTCCGCTTAGANTTCATTTCAGCATTTATTGGTTGTATGAGAGCA
+
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
@r4972
ACGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCNCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCT
+
'*5G</39=-43/:45'*D$>6$,!6678H!@(.1AG4>'80BBE:6%?$+A##=3+:.EGE9*-E.1G*D)E&5.2%A$7B($CF1E@7*$>'"+(;/#G3!*@@'18H"HG+*AC,!1)(3$@,/&D&">(A:%B581*G1!
@r4973
AAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCA
+
+)()(+!$''!%)#$$%$!+!#)%*!+'*!+((**"(!$(#((%&)()'*
@r4974
GCCACTCGCGCAGCAAAATTAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCANACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCNAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGC
+
.E5C37>(-682!5&3(9#7.C@$1:)(!$G#F!7A</6*?9:71516DEE'HG@6><;>-6>G%F$4-",-$F-=*&$&>4,AC/$F9*;3*;)<>A)3=,4C6(7'4:H;D20C55":E=90CA/.3%?2H2-:&53.3<7%@;A+*B:/;@!67A;2G3)6&:8F'#1*E2@<"/,D/%#$$.BC6>=@8,/(((8(&7&$>E91A%045#?FC0.-69G,D',H"!!/%8%:$.$%B47)@4.H0/#B7)!DB!4&H%7D3#19<$$3A&$8*2'7'/G$G2!1A#?",&B&?,&EE0,:)/1&'&3F28H:2(80(1((*"A?)'5CA<*;;2+46>229!@E7><D@=30*D6,.%G,$=08<!-%1E<<"
@r4975
AAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATNAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGNCGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAA
+
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
@r4976
NAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGNGCAGAACTGGCGCCGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGNAGGNAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGNGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCNGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGT
+
'%(+$#(+&*!$)&%("$(&#!#"$##%+$""('#*$*+%"+"!))!%$&!+#"(#)$+&)$#+'(("'!)'#%('*((!***+!**"$"$+("$%%%%#"*$*'#&+#!"%%&'$&'&#&!+'(*#*#'#&!'""()()(+&#$!'%(+&'%$"%%$#%$#%(())*$'&$")#&%%"'+)('*+*(&%'"*%!#&'$'#!!&(!%'#++&()((!'*)'*#%')!*&#)'$"#&&!)&)(&*((#!(&#(&!+(*""!"%!*)+(("'!##!((%+$#*&%(!"()*%&#%(&!#*$$#"*&&$#&$$$!%')$*!&$'"$++(&'"&')&$!')++*+(*&%$*#*'%"+'*)'!$)((!*)%'&'(")#*(("#*"!)&)"")$%&!**&&((%)#()
@r4977
TCATCGTCGCGCCGGTAGACATAGCCGCTAGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGNAAAATCCGCCTCATCAAAAAAAGCGGGGCGACCATCAAAAAACGTGCC
+
6C(H3+5:ECAG54;BB)3*(H&E#C@<$8*8#'#?:F,8A5'94G/E9/EG-!9<GF4318/<*C-2B)FB*"72D861'>=7';C.@?53BH6=+-.GE6=$"?@?7?&7G:&6#,%.?#C%4>3&7=*?C>47F.A"?*,H78>0#7F/;0FF==A*9)=:%9$G&#&:(/&A.G@"%,/<67D$G<%D34:C%G2944<+,>6)<+!$>0C##=>ECB:AH556=#(#DAB9D@85!$$)C+#04!":#,+A*G@0F5$#+9-:=179@156#)4
@r4978
CTTTTACCTTCACGCCGTCGGGGACGGACTGAACCTCCACGCTGACNGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGAT
+
ED112F0$GB/F/C!B!%-!F02F8(F.>->(8,)$:>%=A%A!HF6.&13H+>D263)3<5!.6:3!1)&9!'/6A#@'42#H4>68C2+03;H
@r4979
ANCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGCAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATTTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACNGGCNTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGGATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCAACGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAANGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCCACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGG
+
*"*+*B>"B0@B!%A!G$1%3.)=@#7&+H788"*6F+"(1))1=GD-;271+9F9/0G!$(2(/&CA#DH+21H@+)0AH"4$#BH$*.6;9HG>)=D($1E$B,.@%&5<"1335+;A(%0G=0D-2H1D#1?0C,F(!7:>,!7)33+D8%@,EC,-&$.=G6/?3H!:1AD?&8>(2?G=<E2()0)#6FE@86G85E!7F/A=-.E:4?#<9H0,-04#.0B".%/;C=>6/AAH+0#3;@"&<3898$HH/B0@:3#;!#>/>*H5.6?!@1&-91)$5>!-/3',#;*2?$/8)C3>F)(BE$:)@,<;?*E8C<D.+>;!4-"C>+(;9/??F8:>4C*7F9$5+)B:481430+<7C3=#%3,$=?:222)B##5$9&8#:6>2%<H@E<2DH1)4@#BD/%!-9%(0%C5,)3<>."%.=>57A4+6/E-.A
@r4980
ATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGNGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTNTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCCTATTATTATCGTGCTTCACCANCGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATGATCAGCGGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATT
+
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
@r4981
CNGNGCNCTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATANACGAAGCAAATCCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGCTAGATGAACGAAGACGCCTGGTCGTGCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGNAACTTATCAGTAAACAGAGAGGTTCGAAGTGAACGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGC
+
&)"#)&"+&&'!+$$')%#(%$))!$'!+&$&%!*!(#*'!)$"%#$##%!'#!#""%*(!%))'!*(**!)'+(#$""$*!')+!!$"$#"'+"$&%&$&#%")!"!&$+'$'+'(+%"#*#(#"(&&!*)!&*(&!+($&+$$#'&*&)!$'+%+#(#%*#+$&&#&"*)!')&("+"'"!'(&#%+**$&"#"#(%$))()#*!!#)&)#(%*!*****#*&%()%%!#*&*#*##'+"#&*'*"%"%+++'"(%"!&+'"#+*$(('"%#)(&(%#%#%!(+(##!'&&!!!%&)!+)%""'(#+$$%%)&"(&#"')*)&*!(*&'*('*'&$**#+''&)+!$&(*")%*%'*#("(*"&$$++
@r4982
CATGTGNGTTATNTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTANCATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTNAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAANAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACAAGGGCGCGTANTTTGCATTATCGTTNTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTANCAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCANCGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATNATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTN
+
#')$#"!'')!$%++&"(++$%(!)!("&+)+)'%%&%#&&)'!))++&!*%&"&("+$*'+)!)!(#+")())(%"(#*%#)!'"(+"#))$'++&+$)+!!)!!#('&%$%%%)%'')(&)(+)+!'&'+(*!"*)*)"(#)$#'")*"*(&"!"+$"(+""$&&&$$*'&!')("((*(#"$&***)+"$)#)(#'+%!"''&%!'$))+%(&+#""++%'#%&!%"&+)$"#'!&#''!'#&$+(!(%%$$&#+&'$'&(%#+$*$)#+)$'"$&()%%)*!'*%!$*""%+!(#$#$(''+*$!''+#!#)#(+)"#"'*)&+"&+&"#"**#))")+!$*#('"+)+'!)%(")&)(!%&$")*(*$!$*)&)+'%&&"#(#"*)!*!+)")'%)(&&!('*%*#()*$+)$(*!!%(++(+#%%&!&$*+!")+'%%%##$"))((+#+"%(")!)!)'#"+($*(#!)#*&"+&$((+"#&&$&!(%&+"&+'''#&#$"+*$(#$*"")%&"!)'#$$"'!'")&#'*(+*())#%)%*!!"(((&+!##!*"(&'*&"!+$**'!*$$)!%$*'#"+"+%%&!()%!("*!)*%)'**)+&+"%$!&#%""&$+%!#*"!(*(#()$)"!$*))&'($*+))'*)"!&&+!')(#+#*&')%*)%(&*#'+%!)#'*))'&!"$!%'!((!&%'#$"!*'$)#(!'+%+#)!&*("$+!$+*&#$)$#$&$($%+&%)%)'))*&+%!*$&"&!*!*")$$&++'+('%())#&&'"!)+
@r4983
NNACCGTGGTGTGGCAAAGCTTGAAGGAAATACTANGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGG
+
((+'"*+%('*'($%(#'"##")"%%!%&+$!$%"+!%#$+(*)*#!&)+(!&'#&)#'*#!!%+"##"(&*+%)((!#*%!()(()*!+'+!(!&!))!+%+'+
@r4984
TCAGGTACGGATTGCCCGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATA
+
'$+##%!&*&#("###)+$'*!&%%'$(*+*&*"*+&)&*!*%))'(+)!(#'&#')((%%'!%*+$%#*$"%$#%%!&'((*$)#&$*
@r4985
ACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCNGTACTGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCATCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCNGTTAAACAGNGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTTAAGGAACCAGAACACAGGGTATTGCTTATTNATCGAAAACGGAAAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTAC
+
@3C;DC2B'3)76F9,*2:3?&D)925G@2(".@#%4!A799::%,<718(<5=5@!*"';)E=H0HC8=4C7#-&!<,F0+(-8E!&:*"8+>D21=&%9('?;@*+(#6"629'%7440A:G0G7,,D*+(@&E?,,)-;/#>4?D(36GD?4&?;'D06HFE4>>D<'-2H:%96639E&(35@F+$53<GA-,/-BGG49<-7D".(>E4;0F:5:2$?)"?H8;"B?5'98(?)G:!>G5E5)$7!*E1.AB<!".H*$*64?.>13-">,;/>H@:/,;83&)&6"=D%D4>2*%.B,9,D6*87=8.//-=***?#84@-25(@G8B+=30B;'8;5(C/+1F#:;8
@r4986
GTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCANTTTCTATTGATGCTTTCCAGTCGTAATCAATGANGTATTTTTTGATGTTTGACATCTNTTCATATCCTCACAGATAANANATCGCNCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGNTCCTGTTTAGTTACGAGCGACATTGCTCNGTGTATTCACTCGTTGGAATGAACACAGTGCNGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTNTTGTTCTGTTTACC
+
;;6-DD866+88B!<!A'<06560#=488:)E6@"D"GD1-,73&/$5?C$9-+)+;C?B$#"&E8?%%+92(*;7+!$1,)"#&;/-'26<H:%G(;#,,3<6&@-(?@10E@5E?%%<3)7F?'5%H*E#<G51!:22G40>DDC%EF*H9=$.<9,8>H5&*"=9BHEC##';E4*%0>3+24?.B/(2;61-;F/4F&BE+"E)@?2<3H=;5;)?F?*,.G6%<1*=3><8(+E(?+'G8F2+19!#(+7)DE;3,"46$0'>;G-6@5D66#B69E32(+-73>@&E".9<>FD1C'F21G8BG(#949;8(>?7-$#$F/;/"(/+CEF=#/,9*%C1G&8G-.
@r4987
GCANTGCAANGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGTGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGA
+
$%&"&#+)()%$%*''$)!'*#)""&($+#('((#*""+$$+(#+&!#+*(%')+%"&*+"+*!''*"))'(+(&**)&"+%%!'+!!("(&!%"&!%%''"*#&)&)!%('+)%(%!&+#+$*%)"$*&&
@r4988
TCGGATACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATC
+
)&!&$)+%$!*+#+&**(###"+"+"&%""%("'*+*+%!$*(*)(*&#%%(*$+*"%%#)$&"&()(+#!$$($"#+''&'#)+!!#'*+""'$(#(&$#&)&&*)))#%)'&)(**!+"$#+!"#')'+*&)"&&"""#*!!#(%)!)"%*+&$*()("("*)+*#)("%!%()&++"+"$#""&'&(
@r4989
ATNGACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGNTGANGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTANTCTCAGCGAGCGCCTGCCGGGCTGAATGCCANCCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCATGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGNGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGC
+
*&!!+'('$"&!%#%$&'$%)'#%%)*("'$"((+')%#"&$%%'*#*#'#'&*%")&&('*'"%)%!((!)#(++$&(*(#$+"&)!*+!&(+&$!'*!#)+%**&*+((+&(&()')$&"'%#(!$!&+'%(#&'!!"+(&)(%+(!)+$$!(%"%&!($%*!&!#(!'&$!!&!'("%$$*%!"*)$*((+&!&)&*($"(!#("*')(!%%*$++$'+*%"&(+)(!#+$$))'#(+"))$)!*#+++*%%$#"%*%#(+(+$&)(%*##%#%%&+)))&$!%(*"!&&&*'!+##!""'%%%*%+*#)!(!"
@r4990
TTGGGCAAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATANCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAGTTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAANATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATNACTGCTGTAACTCTCTTGGGATANAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCNAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATNGTTTTGTGCGCAGCCCTTAATNAAGGCAGGAAGTATGTGGTTACANCAAAACAATTCCCANACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTANTGAGGATATTTACTGGACTGAATTAGTTGCC
+
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
@r4991
ACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGNAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAAGTTGAAGAACTGCGGCAGGCCAGCGAGGCATATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGNTGGAAACCGCNTTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGANTGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTA
+
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
@r4992
GCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCC
+
=D8;+,71&G=9=@&%9*#E61!<+/!.1-<0>EH*.@?7'1=
@r4993
TGGGGATGGCGCTATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACNAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGNAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCNAACCCACCTTGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTCCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAAT
+
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
@r4994
CTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCNAA
+
>53(BG31!3./@,A0,D$C45A7*.B@,)9",C'C>C0H:",;B7<?/!-('C$*76$GE""5<6BG!,!H1E4!&,?7B:)709D.#87@@<??-9</06@/5/+D,,>5=?+2&AGF'"G/?79"2+16%7!9,<4>782A%,7D)3>?A&:&;/.909BG3@"5#6>68)%)>'0",&"%5.E,0%;2(C'HA-)7)3;6DBFA-4$(9BEE@%."H"B7HEBHA?%51'5B:B/2:")01"?G)G$6)04
@r4995
TCAACGAGCATGTCTGGAATGGTTTTTCCTGAGAACGTCATGCGGCCTCACTTCTGC
+
<+63D<)F'9<BA"$872='%D>/A):,';C)8<1:$%,:65;H3AGAH'A):%80F
@r4996
NGATNCNGACTGTNATAAGCGTTAAAGNCTGAACTCCTGAAATNGCTGTGAAAATATCGCCCGCGAAATGCTGGGCTGATTAGGNAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGANGGCTTCACGAAACATCT
+
%*)&$*"('&+"%**!$%'*!++(''"#!+'$"*$$"&#'")&$'*!%%()%"&'%$)$&"+#&)##*)+$)+!$#(#*#+(#$#*)+#)*!''&)'(*'')'%"##+'+"#*)%$%*#(%%#+#&*)%$($*'$"'''&'#!"%))(+#'"(&"+$!%'$$#**"'%(*!$)*"!*"%#
@r4997
CTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCG
+
24B(?;<:&1)$(C/!1'#74<4#/5):#.,5E&<"A&10'*:"=386,?5A03(
@r4998
AAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTACTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACNAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCCTTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATG
+
7#><82A%*.'+<.4D000'01.0//&/*A:"99#:6*&3-=-F+&1(.*060$B29"!60H7BH4G.$++,A<F',<>:<3./1H+5'F6>59<7#%1;D67?08B2(51B&)/FA.+E!*9+;1!G?1-G-,8,(,94#82,F52C;C8(30+H33=:F,!*B.#.-H!&",19$2!A3H"6A?)G@0*>A=B.B;,)6D+E'B##G'-H*@H>4,1.D&DH9F4%=13A)B0%G21#(2-.?7,/94G@9?),)-2331;34#7?2CFG#E$6CH;&$8,F$7;4C&H@@%5#==
@r4999
TGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATANTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCNGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTNCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTC
+
9+<C;6672B7&3@7=F8)EA//8C9A%.>A+F"58%".(9+<'29%#@F@3'D!9$."B)$.:+-09,.#BH@?H%FC.=E<&&4+(?+4D*<#/0,A-C7EB-A9.7-G.C3GC8%3-)5$,23E3::@=)6?$93H)<0-A;3,'/1@%6GH8.1.1(C)$$'4A$!2$
@r5000
TCGCAGATTTCAATAACATCGCCCGGTACATGNCGAAGCCCTNCTGCGCCGACGTTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTG
+
G'44$7*=>7?/)+D91E338/E-+736DH:'B69>6@%@E&4H&G8$>$#01"'D4-D&1$+-86"@(BD?1;#1-,*0<'!G2A/$3H-41H"$7&*E17$E":",%<>5;9=%72:&??
@r5001
TTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTGGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTNTTTNTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGC
+
*H(@G74$E/!A/1A/+3*><$$G!'@)C$*2#B$?4,((2+F"7D436<A$*6=/:;.>.-3@,;77F/7-%F(#(-$1:6G6-)64/D:@3F)#?7)E;ED"9<<H80?G#*8<>A@A)/)D8(,;B35?&:<6(<;<>,A'A1@4.EG)"74H>()6H'DE;G1-942'E$HH+F*G:'@+>D1.7)3
@r5002
ACGATGCCATTCTGCTTATCAGGNAAGGCGTAAATTTCTTTCATCCACGGATTAAGGCCGTACTNGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCNGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGAGCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTAATGGCTGTACTCCTGAAATAGCTGTGAAAATATNGCCCGCGAAATGCTGGG
+
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
@r5003
AAAACGCCCGGCGGCAACCGAGNGTTCTGAACAAATCCAGATGNAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTTGCAGATCTCGATGATGGNTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGCTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTAAAAAAGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTNGCGAATCCTCTGACCAGCCAGAAAACGNCCTTTCTGTGGTGAAACCGGATNCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGNGTGGGCTAACGAT
+
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
@r5004
TTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACCGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTAATTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATNTGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTANTACTAATGANTTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCNGCTTCCGGTATTCGCTTAATTNAGCACAACGGAAAGAGCACTGGCTAACCAGGTTCGTCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGGTGGTTGGAGTTCCAGACGAGACGTCGAAGTGACCAACGAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATAAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATC
+
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
@r5005
TTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATANCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTNTATCAGTAATCGACCTTANTGCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACAT
+
DC.#?<4'9#%7E4AC''$F'5HEH;:H?!A;>3@/D8(<+84F469G%>/E4-1H!-&/B!>($4E$12("00B.%(,.D(C>&-0*=&)?4E9&#EG!7&>:A&"3H2;*+H3)C%6)'0A64<'!9/B9:F7+F;.C54*548#@#',%@%<*0*%E&--A:1=H6G/F)C:3G<4282<>3+3.&6689(G?@4>?D=@8
@r5006
GTCATCTTTTAACTCCATATACCGCCAATACTCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCNTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGNCAGACCTTACCTTCGATAACCAGAAGACCTGCCCCTGCCATTTNAGCCGCGGGCTGATTTATGCTGGTTACTGTTGCGCC
+
0(*7?3@/,$!-4?*<2E%8;"4$?,<%2?B!%:F4E$*??*118#,5,@8+-B'1:>,8H&A==H+$)H7=,$9(#@$45,)"4:-E8./((--=;1CHA*("52*'+,">@2/F)'@G+-%H93/9D=,!G>()8$2*GA1/C0&99#<G24/,6HD"$%@F/9-@)>">H;@B';%2%8>+/*(9G4(F>3)C'9!'1=D<&<19+A.4%$
@r5007
AGTCGTTGAACAGTCGCTGAGCCGACANGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGNCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGNGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGNTGATCCTGCTGCAACAGGGGGGTCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACNCTGCCGATGGTGGGGGCCACCTCGCTGGCGNTGGCGACCNGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGNAATTAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCA
+
,H3G6,*=G*<'EB4,*/$B5F%!A39@B'=-,#=EC;2.H:0.#7+/"&B"'#8?,*8F@5!7,,33#>-B*8'5G%8,H=%BD8."/?@#D29C4</>4A0(/59%@%)@G/F=0#;2@&'6(B</:B&.7=;<B%7-G:52#5+#$<H-#C-%=EE6:%A;0=%1$&:=28)7'%#8??7(GF=5%)*?"84-'#,F;:8;%,7D2&)G"$/(*!.AG74:=F83'!G1?.%,A&'54GCF:#(:)9>!3&D$6C9./2?G=;/"$@9.2DA1@;*<*5(#:$3"()'8<D?4D?H%A!9F?-2$+%@H'*7&&46BF&A>F4.:60A'2&FH"45%1408D8)=3C>38;#B'HA,*9#""3B"150.!HE<2334:!2.1&!:G:,-E++C'E.AB!00$(6@37&'7-8G,2/4&737?::!0A"D.-71
@r5008
GCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCANAAATTATTAGTCTGGTGAAGTTTTTTCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGNAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCNCACTGNAGGGCAAAGAAGATTTCCAATAATCANAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCAATCGTTGGAATGAACACAGTGCNGTGTTT
+
D4%!D*"'%.H!>46<&37'$F@7-7&,D&-<.H:'C;A+03?)4=;;?%D7;>5:'(-G%:)5D8$&?)1+*-B-B43!FHAC--".>89G3'%A38#'?;D76>1=$<377.67B*@@C=%)H@9'"E*?$');),C=5:1&H4C&E(9%"'*+5=7637,190,3">;C*&9B<5$0=,!9*5D3D-H?F/);86H3!1&'):CB.<32.AA0->8'G2D5!*52&8HA7=?+#?A?,,8-E#9?9(40/*>3(C?=<'</'<0:%7)5"5@-%4C*67:0"$E?$B!9'
@r5009
NTNCGCCNGGCNNTGNCTNATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTACGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGCTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCNATCGACGAACNGTTTCAAGGCNTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGC
+
"#%)''))'!*&"&()''*(+%%'&+")+&!"+($('$"##%"%!+$!!!#'+($*"'*(%('$*%#%')!!%'+*')"*("+&+(&+#"(!)'"(#!"**!('*(*'+)!$!+#$#!!)##%$!()#)()*)"%&!+*%'(#('+$$(*(!!'#+#&'&(&&*(&$$)##%+)(#'#"$&")"!%)*(&+%+)!!%&+%)('"'$#)&"!(&)"''%'"*!)%!'$"*%!'&(!#)()#!"$)'&)))("#%%#+"')"(%#(++#!%+$*"!%!&%**$$+!!*!#*('$"#)&&#"#)+$('(%!%+*+#'($'+"#+$'"%%)++$+%'+'+$*#!'"(!"(*$+#*%())+!)&%"'"&#")"('&$+)('&%''!&!##!!+%!)%)+)#'"$*+%!'(!)'!!!(#)''((')*"+*"%%)"%)('*$(()$)''")&"!!##)*&!'+&*#(%'+")$&"""#$"*!*))++)&%%('+#+('%%(+%
@r5010
CTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATG
+
,$-7G$9):7D0+2'6%!:A!,:<?0*+?,93@B(+4?GD:>/#&HE
@r5011
TNACTNCNGNNTTNAGNATGAACGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTNTTCCTAACCTTGCCGGGAATGGCTTTGTGATAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAANTTGCGGAGCTATTNGAGCTTATACAGGCATTCNGTACAGAGGGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGNAAGCGAGATGNGGAG
+
!&)$)$'!&*''%")*!"+')"#$&''$##'*$$'*)$+"$*)+%')++#*""(*%!++'$*+"$!(''!")#""#(&$%&()"*+!%"')!)%"()!)*))+'&!"'++'%&#)!*+('"%*+*#!$!+&&!%$!#&+$*'%+%!*!"*()!#)#%)%(!$&')*%'!#&(!""%)''**%+))!*)'%+%$%%%*))#$*"(%#&+%%"#")"+"'!#+*"$#'*&""*('*#!"#)+*#$(&+%!+*#!)+$&$+"#*#($$$
@r5012
GGGTATCAGTCATTTCTCGCACATTGCNGAATGGGGAGTTGTCTTAATTAGACTTATAAACCTTCATGGANTGTTTGTATGCCGA
+
-BAB-8+((G$',7&/395*D3$->*H/@C<E@:E9G98A+=5E)1"@='F>;D>>7+*$!CHG-:/!<=15!2&,5?-$/04:6
@r5013
TGGACNGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTG
+
B<0&:F:3<38'/*0-=#>7*6(?.5,4(*$++?3.F"-?>5H&/@018G,,0.?1.B+<*"A.'2+>#$G-7)*457@=ED89"92')+-.'7394)1=9"?@/($H)(4C0F%:;'C'%>!A.-0.!87-C1*C@=3"";%!6+,6<BC'#
@r5014
NACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTANCGGCCAGAATCTCTATCTGGATAATCTGGAGNCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGNTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACCGCGAGCTGCNGCNCCATATTCCTGAACAACTGAGCCAACGAGAGAGGNACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGACGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGNCAGCCATTGGGGCCGGTGGTATGACCGGCATGCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTATGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGNGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGAGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTTCGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGTATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAANATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGAT
+
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
@r5015
CNGGCAGCATACGCATGGCGGCTTTATANTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGNTTTTTTCNCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCA
+
&!#7A0G6@>;=?HA26C2-'>D27!$&/=54C)=:5#);:&HCH8+4,B').3*3,HB311,'$/A=4()H9-9,34E:?-7F5#12#8-29!/4,+<<<.>#6/C#C<87:-1E?3#$E>1BG%="4)9.CAF>9H&?<06A:G"5(;0E&
@r5016
GATTCTGGCCTGCGNATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAAGGTGCGTGGAGGCCATCAAACGACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGC
+
8+<GC.8#E;)??!9.G#$/%)A8>1,<@:';=)/?B2B*2F&$<B#D9.3$#DF!4:,4H1;C;E*B)#>9B<29$>43;<&,,6D0+D%":;4<BH>?)E&BE2B,/3.EH8GB<;&C9C40.H=$B5=@A#($63@@;%$'+0H/.A;E*($:@,>4
@r5017
GAATTTAAGTTTGATCCGCTGTTTCTGCGNCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGANAGTCTCTCTCTCACAAATTCCGGNACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTNCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGNATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCNTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGGTC
+
!;8/!+0;(+&%>)4%>F;#1016A1>5G.?5&>-EH%/*5'2*:D1-0?3>7"G?.97=>%-CDC5:&.46"&6<&!./@G2"!9C-/B3D1));$FH<1)0'?;C!!@FEF:F>->:1?4:B!.,G(5!F58:0E?$C*28?98H>('08=5+'>)'?G9F3<12''41$@#%8!5@)'G@+D6$(@$!,)>8H02G8=5F*E3D<1"(!=.&D7C<7&,?!.=#;#/1::B4E-G+:$.@+8F-?11!*)#&5":+4"+E3&C0><"%!2C-03;>0005>36AABF#')/?<)+B!*##%602.@0+6"'C!G#=@;,&:!&@5
@r5018
CTNNNCGGNAGNANGGCNGTCCTACAGGGCGANNNTGCNGTGGNCGANGNGNNNGCNANCGANCGGCTNCCNCNNTNTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGNGNAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGTTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCATCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTAAC
+
&'("$)#'$*!")$%)**%&*''()!%&%&*!&%%&&#!)&!%%"%*!!%$$(*'$&$"(&#'*)#&!))"('$"!**)&*)&+)(+)&')&'#+*%%(*%&'$)$!+(*"#(+!$$)$+%)$#('%+)%+$#$(%*&$%##"$%!#'"%"++*$&)'$"#("&)!**(+"&%()$&%*!&'+)##+#"&#!+#"#&)"%"'&"$"!)%**(('!(*!%&)'##&)""(#$)+("")!"(%!'%$+%#$$#$(&*($*"'+"')$"+#%$)(##%$+*%#$%*+$%#+!'(*%)&%#&""''!)*!#'(!'"
@r5019
AGTGGCGGAAAAGGAGATAGCAAATGCTTACNATAACGTAAGGAATTATTACTATGTAA
+
/.A>37;">A/9F8%52>034C'@/FF=;:*E)+G-'<DF0.@E8G3;C1@/6,-!5'D
@r5020
GGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGANGAAAGAAATTTACGCCTTTCNTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCT
+
%2#2/4E0E3A1D=?E7;)A#/#7)=>C"%-BB45)=?1>F*'5*H:#:3?<>G;A;B&6&AAG1$FBD0"-B0C#.(5+6!+%'*1"9:3,"E@0A4-3B=8<D6@C8E61H-;&!35&=6!%>F%$#'@;;#%/9%;C@3*%:37=6?GB6$-4&G&C:FF<(0")1*:$';E*D6-C@(&=70E-!8"!<24$F."E?671CCG.-&E,+1&;H
@r5021
NAGCCAAAATTTGTGGNGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTCCATGAGTTGCCCNTCGATATGGGCAACTCTATCTGCACTGCTCATTCATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTNANTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGNGGCAACATCNTCACGCAGAGCATCATT
+
"DC-#?H=(?:.);"":%$H+":;;2!8.(C%0E?A77D-,:(E59D$7%(#D&1<2.*HE(H@A<@H64=H2))?E%*(D::/!-HCH>;F$:3HE!-/3BC1%#.>E)1-9B'$8$$?&4.=EBBH,<:*9/?C;0400@8<94<84G<58-*4/3=3((4,<5=H:E#&$%A=E*5"$D"9HGE@=D57/G'C:;-'>8GH(==4660C+E?*@4E94+5H%=@*D>$4@0E78.@(;F(3+*'>7=F0'")@<)&0>:A-/?*5-,,%1H&?65>?'AB21<!<9!A#*?&48(0:7;93G9;&?<D,H!($(*+>;!;GH?=%.4<HH,)H/!H!?B;933E<'G67;6=5=/:$=#@B8.(!6&(?7<$&;,,",=/#?45;9G;F#
@r5022
ACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATANTAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGATTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTNCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTGTCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATA
+
9"!?G(0A&=0#<F3D36*.5E81-9"9('FC"A7>>,%0!F@@&#CF'!"#-&CF#F6?<@A+=4(6:6?'5!$40C#G;/*&>B)3!BA)1@<",$/@*=6?*9;&22/:;D?H;3G516%<$?7G5?!C@A!D"+,B7G,HD5"G"8,42%H3DF,H-("!,&0>&!8?9CB;-2;A+?+6<@".%!ED-%8B;DDH5F'"A!G?A!(F/F:,.(3$&@-7>/&>@5:GB:>#0.>*<<A2E!,&2B(/<"%,5#&89;B4H7*?-4B9.F%!2FC)/B>C7!?:G%G'D;.A"4>1%"65))$A@(9D9;8-.-?)B%G$,<3&:4+*A3*3B#=DD++%G(16?2/F70F4!2.6$.?:BE11=%&<4&C*8DA+(5&8$6EG>:+&A14*"9!5E/1*26$7>*D+8F%8!&#4*GFB,EE7A+2@$-4+:B$14'&E7#DBG:#7"72-79H1'=?D.'.#<-$%@A3*H<#-=!;+H."4.B>!#EB@5(A.0:1,A32:<FE0(H85E@$1+&2A8%-:*&A
@r5023
TNANNTCGNNGGNATNNNNNANCGNCTNAGNTGNANNNGAACGNNNNGTANNNCGCCT
+
"##!#!"$"$!!!!###"#!!#$$##$"""""$#""""!!#$"!$!"#$"$"""!$##
@r5024
GAGANNTNTGATATGCTAGGNNNCNCAATCAAGGGGAAACCCGCCAGCGGTCNTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCANTGCATCNGGTACGGNTTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACNAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGNGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCNTTATAGGAAGTTTATCCACAGTTAAAGGAACNAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTNCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCA
+
*"*""$!$)"$()#)$)*(#$!&*"''"&#+!)"(!)%('''"!'*(++'(*$'%'+)(+%+#"&"$('#+("'$++($+&)*#%&$**+%"%!&#%!)##%'+"*(#"&%&(''+%!'#)+$"$'*%%""**"$'$&(%%)%"&#&%"+&())"&"'$#$'!'"(!!*+(*%$""""#$!#'"'$('&'*$&(*'*(%!$!)%(*%+&&$*))$#)"))*+$*!"!$'&$#'!)&"%"&"!'*))(!+*''+((%&!#+!#*!!$*(*$#"(!"*#!+)%'&"+!+%"++"#!&)+&"%+)*"+)*+($'(&%%+$)"!%&"""!)'*'("+&+&(!#%+'"+!#"(''!'%)')+"%(#&"%')!#)*+#+(+*)&('%)+*%)*"(+"%!!$$"$'!!+('+'**$&&$&!)#!&)%)+)+(+"$+(#!)+$!$)+&##'&(&&""!++''!'''+**+(&'"#&)&++!
@r5025
GATTCAGAGTCTGACCAGAAATTATTAATCTGNTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATAAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATNTTTATCNATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATNCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTANCCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCAACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTTTCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGANAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCNCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGC
+
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
@r5026
GCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTNCCGTTGTCAGCGGCACAGCCGGGCGATGTGCNGCTGTGCNGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATNCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTNCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCNGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATNGCGCTGTAATTCATANTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGC
+
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
@r5027
CTCCACCGACCTNTGTCAGGTCGATTTCCCAGAGCACCACG
+
#8B:&="(4C#2=H:/>09DB8AG<?$FC=D)$$'&'C%#@
@r5028
CCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCNGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATANTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCAGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGNATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCNGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCNCACGGGCAACCTGTGACGCCGACTGCGATNTCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAAGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGANAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCNTTCAACGCGCANGCCNTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAA
+
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
@r5029
GNTNNTCGACNNGTNTATNNCNACATAGCCCTTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCNAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGCCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACNATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTNGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTNATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTNCTTCCCGGGTAGCAAACCGGTA
+
*"$("*"&(*"$(&!$)'#&'!''&!%&#&&+"%""$*+$''(%"(%$#(!#!'!%!'"+!&(+&%*(%#!!"!!*!'(*&)"&$#)+!!%$)+"*&)()&%'''(!(!"(#%'!**'+&&($$&&(#(((%!)'''+%+"!!%+"(&+*#*$%"###$""!"*)%%%"#++(*"#&+'+((%$((*!#!%(+*"**'&$&(*$!&%*"'&)"*'($#&#(+'$$&#+(('%!%%&##")'*)$!$!+#%$(%#$&"#$!")(**$'$()&!*'%##"+!#+#+&%+"++)'$%&'#)")(*'(&&()%$(*"'$*!&#($)"#!'""$+)(+"&"%*%))$)#!(&(!'&!)#!&$(!)+&$!'*)%"+"&"&##(*!*!(!%$*&+!&$&*(!)+$#"#&!%%*#+"((%+(""+*"#!#*$)+(*$$*&$"+'#'")##")"&$'"+&!#*!)"*!)%$)!)+'%#)&$)(#&$&"'(!')((&!%%!$'$$(
@r5030
NCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACNCCGCTGGAGAAATATGCCGCCCGTCAGGAAGAACTGTACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGG
+
!@7$<FB0F6,@#$"0*/7*/*&EHCG9.6+D(A-9,>-;'#1?9@D90#D8$=0%G70DA-F;/.3C151&#<<C$)!,;7HD237?@<EH7:78F/740B61"H"?,0B3E1<%CBFG</1&:G,DB>'8$H9CDHE$!;30:,,&;:@0&%F%;*B/D8<&H$<D;:>")$@=3<?.D"%*>$7
@r5031
ATACTNCCGTNCNANANANNACNTTCNNNAAACTCACGTTACTCNTTGNGNTTTGACNNTNCTGTTTCAAGCTCAACACGCAGTTTCCCTNCTGTTAGCGCAATATCCTCGTTCTCCTGNTCN
+
!**&)#)%'%$)"'$('*"!#%"&&##)#)#)*(&#'$""!)&'!(*#"*)&$"*%"#!&&+)"&#%"(#%"&'(&)#"!"#'##(+%$(""*('*!%+("(&()%&+$(&$+%%*!+$$$(+
@r5032
NNTCTCCGCTTCGATAACTCTGTTGANTGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCCGCGAGNGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGANAGGGCAAGTATCGTTTCCACCGTACTCGTGATANTAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACNTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGNAGACAAGACACCGGATCTGCACAACATTGATNACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGGCACTACAGACTCTGGCATCGCTGTGAAGACGACGCGNAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGA
+
#++&'"#+''!$(%"!)"'$(&$&(+*!&''"(!"#*%!((*+"'#"*'$'%*"!&$&'&*""!&'+)"&(#$!"$#$%%#($!%**%#$(+*%%'*(%#$%+()#%**%($$"+#(&$"!#"'*'&!&!$('$)*+*#()%(*)%*%++)&"'+&)(%'%%*%#!'(&)+()&'%*(*(!!&("%(+'*+&)#$))*(!&&''(&%%$))%'#)*)("))*!#((+*$+'"+%#%%)$(*$+(+!!))*'$&&!**(#'$%)*$#"*'#(")))#('#%#!'&$+#*)&(("*!#+""&"&"'$%&!*++!++&%%'+%+"(#'$"&#("%'"(#!++%)**&)!)%""&*!%'(&$&&(")"$*'&"&$'!%'&(*$#!+(&+$)+)+!()%$!&)##%(*)&+!'))%(%"(+(#!(("$"&&*'$*'&('#%!%"#$$()#$%("**&%$#%&)!!$&)&&&$"'*$#"'!*!&"$"*$*$*+(*#&+"%!&"$!*)$#('+!*&!*"'%&$$*$$)%$!%#&#&'+$(''$(!*')$*#)&(!(*)""'!)#+$))&"$+"&)*'+#)'&$+&%+#+!)"($(!&+!*%()%(!#('"#()(*+"$+$(#"*+"$$!(&$((*&&!'#$+"!!#&**+!#*""'+%#$+"+&#"!
@r5033
GGCCCTTTCCTTTACCAGNTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATNACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCNCGCCGCAGCNGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCAGGCCCTGTCCNGCATAGCTGATATTTTCAGNGTCATCAAAAACACCACGTATCACCGCNCCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCCATGGAGCATCGNACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCANTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGNCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTGACC
+
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
@r5034
TCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGNGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAANCGCCGGGANCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTNGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTNGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTTATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAG
+
1>)D36$<G3"-,:2"0%H4H7!8$?/!D@#-31<+7,@$:'+276?B%89:1)%E1:E+B,A5'<$,@-6923;!:/,C72%1*?(F#+F#3"A80!%/;C;C%H?ECG%,/F-&8F+3H3@'G>>7%AB.C!<F'10$?&1#=!%22G);4!+1&'C"?6022;8F'8@!5!?B>3)%-D/4G"F31;4#$'6<F(;9EG5/@1:4H"93#HG!35B:5#6D&#5?(@G5A;<81D)8(E=1EG2BG+4-%/<!E*1(351CD&-7'<(@@+6-=%781H.)'?H(!"&!#!(0'$;342GGB@&/":.#0>71!7B<F'@G'##9:*?.3DC,D;.=E<>A97),*-254'9F0>F$5.-)6(?)!1@.,3+,G5D(5D>G@(1F.'*+'E(:7.8'B$&1E++.:?6DFB=G+024".<%/.<!8!,+A18:-
@r5035
CCGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTCCCGCTGACCACGGCGTTGANACAAACTATTGANCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGTTGGTAATAAAGTGATGAAACATACTGAACTCCGTGCAGCCGTACTGGTTGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGC
+
$%#+)(+#'!$((")$+)%$"$!"+$"""#$!#(*"$)""!(+()(%+%#()*#(&%'")*&&'$%#(+'!+((*!&(%+!#!$#'(%('#'#!(#$+##(+#$)+#'+$%!!$"!#$%'"'*$'"&#$#$"")*)%*+$'(''("(!)!"#(++*#*$$+"&""#!'$!*"&)'&##&%+($"*&"#%##))(!!&+&%(')*(+**&+"'#!&!!*)++)&+(&$+#("%($*&$*%+((%(!(%("+*&"&((*(+#++$#+"$$'%!#')#""(*#))+%*&&)!$)$')(+%$+"!"("!!'!()"#+($#+$'+#)""#(!(!!%
@r5036
TCTGGGCTTCACTACCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGNTTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCACTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTNCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGA
+
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
@r5037
NAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGNTACAGCNAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTANTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATAT
+
$5$C5"<.4,!=/AF,)!@'ECB$&%B%CB/D,,H=9E'<<D)+0<>6=D(H?HA020,!=$@HE=/.*?6>A=2;/D>/*+@,@F!$2G-/;+"28@,-2!475,20"A7?;GE=3F.&7)#8/67?E,&*407<C;8C9(%?!23,!.?HHAF(&&"9%
@r5038
CGCGCAGACAAACNGGCTCAATGGAAAGCAGCNAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGNTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAG
+
,%9-D*"5BD3B&:D<)7H6!2,?AG$%!>E.+3=2''!B($$-#"64,/0CC>74!303E%?BAB6/)2!'0@7*534,,:$G@@:B'4H9D6;.&5F-B99-#"0+#3>4=848060E@)4=>GD+,$4C!.A&4:DC7G?;*#%"=1!7/?.+%0/=:8::@FE&/1(-@#'<D.=>7E+31<#)!,GC.5-
@r5039
NCACTTACTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCGAAGAGAGTNACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTATTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTNAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTNGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCNAAATATGTATCAANGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTC
+
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
@r5040
AAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGNGGCCGGAGATAGTNTAACAGAACATTATCTANCAGAAAAAGGCCATCNCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATAGACTGGAATGTTTTAAAAGGCAGGTGGGCAAGGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACAATGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCANAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGC
+
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
@r5041
NAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCNGAATCACTGGCTTTTTTGGTTGTGCTNACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCANGTGAGAACATCNCTGCCTNAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTNTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAA
+
!-"+:+42*'-9<=HB<</':#@3!@<&32GB-F(CH*?:%3!64E1*H(@-E&!<'H>74;::.=2(*&H;10D1=D"/"+1,+.8<53EG#,(<<>.-1$#%7F#E.*/64"H6$*"&A><<"HHG4:+:-?+?+5,":D.F60&5!%8$(+D>A>.90!6B"('FG;2'9F1=%A?=-1"#DB2G0FDG"8:E?/10)+2<4.HBE):"A;)#E'4GF#D6HGB#7$'115@,>+!6",!$&8EF*F@G"6?>>;3<:F0@$3>2)'*-!?<G<5*C"+,&-);79B2A:#@B;$?>F.85G1$@?-6+33(%E/)H42+!*-3-C,G;C7$7D=2A0/@<0)'D(@,.3A3AA*.-/#6F+!D>#..,.H1#;&FE5A"35G/+7+4(2B-&*(%;74/GH,=&1<&3H-C>=&5%5DA55F1/>-3'#;=)'#;'!:9332:CB#*1"ED>C">D>9?$:<4?E+'?;3:.4=
@r5042
CAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATNTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGNTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTC
+
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
@r5043
TNTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCG
+
"*<#D&+,-C9G(&6@%(@2AA?&-=&?==DED#*@C(>?(G
@r5044
CAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATNAGACAGGTTGAAACCAGCACGCGTTATCTTGGT
+
3(!?6H$1#E-*9.54/#@B/C*-'@)>.(#C'"0&;F5!H#-;5%-#=>&25-5)2;2?50)"B#@3&A8@2..",FG.!9B13%=,1306?H%)%GFF4AD3#1)98%/(4'G%$"BE/B%<.0B)A*C:H>'2,:%:-"-"A43/,6)%,#-%59
@r5045
GTTTCAACCTGTCTGATATCCGCAATCTTCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAG
+
34#1(-)(<@9<*+>"(D5=9=B@:/G&&%"%25"'>.E)"G<9*!.@!7,#A:D7C)9=<C6:*?<3A.D426.'0*:'
@r5046
GCATCCCAAACGGATGTTACGNCATAAAGCCATGATTCTGTGTGCCCGTCTGGCCGTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCNGAACGTCAGCCGGAACGCGACATCACTCCGGTTNACGNTGANACCATGCAGGAGATTAACACTCTGCTG
+
,G*#.D(-8)$7"*?E-@11BD4E%.3#0)+6($&F60="$:9-;$H;B&8$E5HE(:;#8$7E':8HE8F<2&/B<G@(59!3.="030B;6=#AA3=8-.,G>G:E6EA&#H!@'78'83<5"=$C-"!E,,;;2AD"&H8)-F)E@G6>.,763@EA7*:G#GA%?=B:G%<3&E+%B$*F,GE@.F!<G
@r5047
GGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTNCGNGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCG
+
:?2%()BCH%%8D!&A*2HG!/E#5=('0!"*H6:#B3)ED/F4!*FG;3D+!>402EHAD$.*/(&=C&?8(6,;39.68:-@'9(#,()$H%=)&.<G:?7.-(CG6!7)31C"H&.=(&=96-)*4-73<@3&C:+4(/*D@:07%'F(9/B9%?F6<$16.!
@r5048
TCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGNTGNCTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGGAACTGCCCTCCAAATCCGCTGCCACCGCCCTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCAAACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGNTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCC
+
=>&ED"A/-,B#,51B'B$8BEG61A:/:.E#78?H"D>C9-77+7-+E<9#<66;B0#"C&.*8*-##B)-B+):3=12"G,,A4A70=-<*>77D@F8D,,24$00=&89F=%900:?0>)4$;$349")B=.('/7A=G&#9&6@B?B=&E<+B*;)<!;"$6?7A!:62B*'/+'?)7D/&'21G)28-/;8"EE:0%?=>+)#E%(6A"!'E(':36<,6!6'*3.G@/*FB088!&@29DD998,4%=(A9C9<8*G(-2%.:<'?4,1-!:4-E)0:-,%),91FA-!F,"64#A82E,&.6$?9%3D(EH:0G9&/'=3D-DFA16.;<:868.:8'989+D!H86,&=!1.?-"93DCG=:(H,;1?G-2@1*,F386!:+'@7G4;?-';0(H@2H=+>""2=3<B459'&7@G8C6/8"CE3B6>/)!087;C*:589%4".CB!*?'5$/0=D.<9%+
@r5049
TGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGC
+
B(?:B;+5FH741>H#$)A61"(?:$03'E:H@9*!2@&)%=96.H;>F(40>C,
@r5050
GACTTCAGGTAATTNGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGANAATA
+
3?67A3E2-%G;G9F&$):3<G856+.321C?%?,$(!#3(,;"E(6=&#9E$#@$.1;
@r5051
AGNAGNCGNNACNNNGTCAGNTGTAGNTGNCGCATCAACACGGATCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTG
+
"#"!)$$#)!#)#(#!#!(("*#%(#$$'%"*!*++'&"('#"))#"(%()"#'%+!$%'&*+%+'"!'()#(*&+*%#%+%+%('%!%"!)'&%)!!#$*
@r5052
TCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCTTCCACCTCCGGAGGACAGGCCACCAACACGCATCTATTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTANCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCN
+
?AF?(&C*>;(<-EC.$.-A%:H3D35"*!+6/'=8F.-15>.G(&-14AE''B0:55&8/16$H386.?&>;#>:<'8"?*4:':A$H:GH,0-HG=%#6:!73+5<,5'EE0-<&'3;!'9%8&7H<1'#7;HA5F;A;F$HB,>1456@C&0@4@?>:2(=A58CA8D8>A984,?F:1)@)(5!/F<H4<C919'>FF>"""B@3F-+BH1HA:2"ABA2<-21
@r5053
GGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGACAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTNGATATGAGGTTGCCCAGTATTCAGTGTCGCTGATTTGTATNGTCTGAAGTTGTTTTTACGNTAAGTTGATNCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCC
+
7%=$64D11BH,>69;?E6GH!5!1"%0#EE,:4%)6-6CEF*A<,=%3:6@!$B$D"B,HC,'AE>*H5A4@47.;%E/;(3DC!>:#>)-#03>'';G4D34;/C>*!)5,&6#(;A2GHB8F.F/,/7?-$:E@;F.*/?=="<"5&A0'9(7#=;.7'-9/6"@41:9'3)17<4H!?6B3H15<A+0"$G)$H'-FEC0093#,&7>#)G=-)*;>1H**('*;"F98%B#)/9F!<9DC=G:ED%2A(('CB:>)%,HG9%(;+-/+?&AAD."#1::!#.<%70608&H?;<$GF.%#F=2=&0E=D);(F7($2!C<)+'>A#!@>8)C7CC(1A?&4D791D=C&7C2?<,>4.$8.&F<==!6;&-H68+/8>42@951GE5..*G%+D%(<ABH;.&A%+2!$*E64A*!9:F!1(+*)-A$E-6,*-,8#AD!-!,*,:%-#-H3'-6.08#2*D>A0(=8D6*516:0.A<2B+.B)4-.8F*"=!)E/@81B7&;HC7D*:*D=9;GH+/>&6,FC1@@A=@'FE'8.*)D/*
@r5054
CACATCGTGTTAGAAAACGATAACACCGTNTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACANGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGT
+
7E"5G'+/FE*?1:C?3$":<:.*7!E"BAA;-,*B-F8(*/B,$3:66=72;:?5");&81%E%=C)2'#@'G7;7'.3@+-)'H+148DE=FE8B1/.GGD45@+H:1?C,?/A5:"H&'4>C48&$&".A:?D560.:'E:@>-7G:CEA0A&8F:G<04(20A
@r5055
AACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCNCGATGCTTTTTGAAGTTCGCAGAATNGTATGTNTANAAAATTAAACAAANCCTAAACAATGAGTTGAAATTTAATATTGTTAATATTTATTAATNTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGNCGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGT
+
D98*,.;.&"C$;!3A)/$<$(!&2%=D%)9&76*><<3C%34G>A,+1,*EGH0B1B,7;%%<F'H5/@DA4D/A957<D'%''0G/9;*0#-FD)"B7=9<-+96B8@/<31$/G#"#G!6B#@%-6#.D"+9-:%83.BA:,89+?AG7H-G@:4*1=CF30764&1";D9$$)=7.>*4E187H7D>'B"@)<%7F)66:8)?>,?GC@F+<)H&BH.%;G$(4&>9;4A/B?D:;-!>B'6,-DG4F+%B$>-+3>%)@3,?+17!'EA#!8#7H%G6%D+B1!12F2&A="BC-CH,=4D4@D,7,>'1,5(7C&""0
@r5056
GGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGNGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTANCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTNCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTNATAGGTAATNCCATAAGTCAGATCGGCTGAANTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTG
+
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
@r5057
GCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCNGGAAAGGCGTAAATTTCTTTCGTNCACGGATTAAGGCCGTACTGGNTGGCAACGATCAGTAATGCNATGAACTGCGCATCGCTGGCATCACNTTTAAATG
+
+7"!@*F.2B7$#H8,G&D3<%@;D"@7'G,!"'9F8$,="/0<E"%C<*!.'+9"A/E*E-;+'85H>"EBG4=-5@9*1@?,!?4=)$CE#G8!E,A$@3"((A*B88A#8*1:7<#,A89;21<F;$/273EB?3"F@5C?FE?>1$F0=2B#./5+F9F:G%=;A9D:?"@83-970=2&2"&D&C:4F=:CD9@'+'>:"==-<$-'A@F5#??H<;='/%)74F76F899745$G(E(52F$?2C/#5
@r5058
ACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTNTCCCAGCCACACGCTGCATGNCATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAAT
+
@"1C4@)'',4.3+D2F54,2D-#;B:3;B(B20FH<5;"#H>$4)E?;A76G/BEF!F%0+<";&F,;2<221-H=71G;##-,E>(?@?CH'##+/E2"%$0/88?@4
@r5059
CCANATTCCTGAACAACTGAGCAAACGAGAGAGGTANANCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGG
+
4GF0,!'@9;77"/(F/"5G/4"(4!"@%4C!,GF">3AE2%;A@8F=('A?A;":A>9?+9%.6G*FA>2F*9DE%<9FG"
@r5060
CCGAAAGAAGGCTGAGCAGCTGACTCAACAGGACAAAAATGCGCNGCAGCAGAGCGAAACCGAAGCGTCACGGCTGAAATATACCGNAGAGGCGCAGAAGGCCTACGAACGGCTG
+
'@%$@>0CH-2B+-'H&E+)5;0-=/.6<HE&*F)1+233>*!;3!3'1AG$&A*HG'156>".A:!-41;%=/6#1G77D!"8>9#(,D"<+D$">/F(>-$A+-1:5>3A48%
@r5061
GCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAA
+
&H1FD$@)F',C6#12$3+;6:.2+#/A$"+#465&BF(<$-G-?B*H@C*#*$"D7)#6B44(>C*'(),0@6$A#%D=G3$>H+3,,94B8!>*5=.27$*(6!D=C*-+$3D5CG78$%G.(;D-(9==4::DG.)$;5?10FC58D44(C=&B)7,=-71()%<(-E>E
@r5062
CANCNTCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATCTTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGNCTTANAGCANTTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCANGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGNGTTGGTGCTTTATTTAATGNCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAA
+
($#)!%+%"'"*(("'&*+$#*$#"#(#(*"""%*$'#)*!&%&#+($$!'')'*'!)")()!)&$*#(*&%%#"%&&&+(&!$*+*"&()")'#&!()'!$+%#(&**!(##+&*()($*+*''*&&!'")!*'(+'!!"**%$#()&++&!$%$&"%%&'))'&(+&$(#++&&&+"'*)&!%$*#*(%"'*"%**$(*%"))"(##$'%+)%'!+"+%%*$($++!&$##*)%")"$!('#%$''&(*)+#*+%&+!*+'("&''&")#)
@r5063
AGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGNCAAAAATAAAGGCCACTATCAGGCAGCTTNGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTAGCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGG
+
9F@C20=5"=3(@!4#E+10,A1=%*8!&>(2@5%/.:&&D*G+)*$0'72:&24$6B=GA+.;6<&BF6E+ED5"(3(1"&/?'1#*FE+G?+"9&6!"&BD254<9';!F;BHB?H<A)/3>+/58#3+8+04D+<?H?+E%)B=/@&0/.*0$"#6B7;:&E$4=;&FA(+0E!#0'HCD/)?7@(+1&D%<H"39-
@r5064
CNNGNNAGGGGTNNANGNNTACAGNCANATGANNNTCNGCNNNNANANTNNTGNCTGAGANCNNCNCNANNCNNTNGTGNCCGNGTTCAGNNNNNANAANGNNANANCNNNNNGNTGNNTGNCCGNCNNNNANAANTANCGGGGCTNGNANCCGNNTGNANTNNCACGGNTANNTNGNNNNTNCCCCTNCNGNCNCNCTCNAN
+
""!$#$#!#""$!##!"#!""$#"#$#"#"$!!$"#"!#"$"!$$"#"###$##!!$"#!##!!$"#$"!!!!#"!"!!!##$"""""#!!#!!#!!""$!#!##$"$!#!##""#$!##$"!!"!"""""!#"!!"$!!!""$!"""#$!$"#!$"#"##!$#$$!$!##$!"!!##!"$$"$$!#!!###$$##$#!!!!#
@r5065
ANNCNNNTAACGCGCCCGCGCTNCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCNTCCCACATGACTTTGAATGNCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGGCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTG
+
&&"))+%*+")'#$&&(+&$'&"*(*"'##()&'*%&(+*""!)&)+()%&!$+("+&%&"*&$##%)))+$'*)!**&'!+*+++#+++&''+!&&*%&*"$"'++&*#*%%"(("$(&#%*!($$""+!(%)""!%%+*%$'($*)$(''($!)##*("###$(!"#)$(""%$$**++)((++&#'(!)$")+%##)(*%($))#%&&#"+!!)'(%#%)$()#+'$")")(%'&"+"%#%$'*&)(&#)%"!)*$)"#(%&+%
@r5066
GACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGTAAGTGCGGCAAAGACAGCAACGGCAATAC
+
FF?,6/;6+--=9:GH26<,+5>7E/1$H,?:F'%'&'E@(F9&,.57?=(3G;*E;<G3-3/!,2=":#/##70(B/.<*@A@AE&/#!&:.'0E*5?A.,4!0>@&F;;83=3/1G"A*G6
@r5067
TNGNGNGCACGNTNCCATCNATNAANCCNTTACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACNATTGTGNATGAACGCTCGAAAAAACATGGGCTGTTCCGGNTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAG
+
##(")&)!*%%'""())(&"%%)%(!"###+%%+%&((+'"+&#&))%%#%#"!"#*+$"*+$*!"%'&)+#%(*'(*'&&&))$!!%&'$"*+")&()*'('"'#&(!+)+*&*#"#$+('&"&"+%(*$'"#))'"%&%*&'*$"!))#'&*$+)*"!"**$"%!(&'*'"!%%"(""*%!"')&&%"&%%+!$(#((#%!%'$(!%#$#+!++(+%!%$*#%''#"$!$("("&+)&)+"'+)**(
@r5068
TGTCCGTTTTCGATAAAAAAGCAATACCCTGTGTGCTGGTTCCNTTAACTGTGGATAAACTTCCTGTAATGGTGGCTGTTCCATACTGACTCCAGCCNGAACTGTTCATCCTTA
+
+!#$#)!"!()%'(#(%***&'+*!$"%)!"#!*"$$''#**!%'!!#)$'$$+&*%"")'*')%&$()!&"%&%&()++!("#'#%#+&%$#!%#((!'!&!%*!)%#"+%!(
@r5069
TTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAA
+
CEF6!>E4#,&?;=-'""5,;)(!>6+1=$'%'GD&=:/(@'0'>.3</*"H=/5&!)H./7,
@r5070
ACGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACNAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGACCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCACGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGNCGGGAAGAAGCATCCGTTACCN
+
B-;'9D-.*(;&9+:77"B':2"G:8"#B;!2(H#9*B7!$(<%>>84EA65*"D>8G,G@/416+DB.>!B".>&EG4DCH@C>*:%'8,E*)8*A*5/80,9''H;75&*03@D#-(5H2-1>0##9-H$-@HGA1D-#);(&?2*06.76"7,&8/<$C0!D@/.4)E2?<)%0@G#&#6&7?0/+@%H9$/6C54+$95&F:"2%G4HCD8%H5>F**7EF5/4(<.;07G%A6B7@"H&4H,%-5A"8A-@&6#$%"4-=7,@BF
@r5071
GACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGCTAACCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAATAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCTGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTNATTCGCTCGTTGTGGTAGTGAG
+
5(HG@1"HG<@%7+A?:<13&E-0D10;E2=5/8%1,4=G46C(.'"%7)-1B,)-;'01#<66::.:==DH!D7'-+EB7!3#(>)&&.B2+GA;/0E0.GD:%"'=+DG*E'00@562D;F+G'>E!F7:@/9;:BE/6(A9;4G8A/)58+:D3:6:2&F;'98!7*,46%*G$<.@00:145;9?36:FA;+9#B4+?H@1>-&7-=+?D"%/GGE=.+BFE'-2",F/?;F</A>&8?'
@r5072
ACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGNAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTATCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGA
+
(H@7.7G:>98$+";/85E-:&1(>%8.#6951%EG9.H=>954?HD;A$,&;4.)';9(99+&C+A'4.828=5)!?0*$>+,D;@41<>6*$?&>A3&7HCG)>DH9/5CH29:"(.!@;-H6<@(1''D9600?)8GFE"/049701=FA<*CHCF52EH%G$4,F+AA!#4).&;H6C7AC8"-/=(C%!&A);(AB-6$*90=%C=+F!1@6)72=1$/01$A*=;#1:>.H>D;4EA;BB&+$81F$2#D60-F:?.(3;>*368?/6;2D71270B@D0;=G"#6*6374.+HE$3062-7',E3D05-"2;5B?8*$&3@@'<-/;&&=#4%BE3)?G=258%6F+4):>7?:%;DA=)=AA3(0>FC4E2+"191'84B//2633)0;D!72259.1G&6$@@
@r5073
AACTTTTACGAGAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAACCGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTT
+
219?=8%F:37FE<+.%A2F7+"9'1#+!H69#!14>=$:67#1'#-CB,%!29-:8$B.;@CG%8;#+&D?%44E@@:0("6?0H126D>8;=A%1(68@<7!+02DC35B,F'.0D.
@r5074
CTGTTCAGCGGCGTCGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGAGCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCNTTCAACGCGCACGCCCTGTCCGGCATNGCTGATATTTTCNGGGTCATCAAAAACACCACGTATCACCGAACCTGACTGCTCACCGGATTTAATGGTGGNTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGNAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCNTTACTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGANACGAAACGCCGTTCCCGGCAGCACAAANGCCACANGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCNGCTTCACCAGTGCCACGACCGTGACCAGTTCANACGTATCCAGAATCACGGTATCTGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTNATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGNCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTNTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGTCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGC
+
%!%)+*&*#&!*&&##*)*&+&(*&#"+*&)'++("*"($$+(+%(%"#%'$**"'&%+%'""'+&)!"*&%("(+!&($$))*#$+&#&$&++!!')*'&#"+*$'((*"&*%#%&&+%%#+&$&$!+##!&#"*'*'%((!+#($)+!#+#)+"#)%!&*(")+*%')"%**%+"+&"'""+"&*#(*#(&$%!(&)+#!*&!'(+))"$$)$%(!'#+)%+%("++*!*!(!*!(&")$+(("+$$*(#&))**+!&%$')&+#&%+($%&%!"%#$%"%'''**%)((&'#'''#+*#+)+#)&$''%*+))&#*%"#**)%###((()'*%!#"%*)$$*%$*((+!%*&(!)'$!$$"**&&+!*+&)('+$#+#"$)'**!#"$%&!'*(&%!*)%!''!"&'*)%"!*""$"&!"!!!'$')&(&(&!'(!'&+))+&*&""''!('(+!"&%#"++&!"()+%+$*&$'#'!)+#*)(%")(#!&#'"$$#%$#(("')+(((+#'(%(&*%)(!+&$*'!*#'%#%"')$+%$$""%"(&&%"$$)%'+&+%#(((%)+%)$#)*%+)'('+"($'#)++"!#&#$($)'*&!+#+$**(%**"'#""+(%)+"'&#")$""*$+##+&%$''"#%%)%#$")%(+#++!)$+!!#)$!)%#)%(!(()%(%()*()%!#"!#&($&)*!'%$"&$'!$!*+($#$("%*)'!%&'&&'$&$&'$)+&#!%&++%"&*'!&')&!+#%%#$$$$!%)(+%!*+&$*)&"%(&)!("#%+##+(%(&#$)++%&&%+$#&#+"#)"!)*!!!%&"%'+*$#+(+%%'&*)"%)*'#&%$*$#"+#)$+)(!
@r5075
ATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGNAACCTGAGCNANTNGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCNCAAATCTTCATACAGAAAGA
+
8.<<9#+8!8=?FF"/4<*EF97C)-;%?.$+49@6+'81-5H"F(D",*>%952&"9?=CF31/+>4>C#5HHAB$9A?;##E2@%'503,,4&'F'<A21CD4>@GB7'9334>FE*H5F"3;&)+76:,9?G#8H)8E;965?@1>-+))-$@72<429@:9%4.4C7B=.'5-,(;7-$6?"?:E9E@.?:%(:+$=#0F'?/7*!<76:37#.2!0HH1'<$"6E9"/%E!&.@)(2+57E8%/***(F-EE04-3/4<@'":8>!!/51+G-26&,:5)E'".&.$.43B)#@>!3B,:C@0(/(<:")02B2>+F*(%*2G?'73:D<"(BG@F$4F;.B$7C4F1)/>!"GGA*4-H!=)0?+;$EC;''%:$+?1E$%<3D.=--</(5CA01G7$-D!"-"$6:#/6@85<.3G:9A6;7278//C3F1!6@B/)8,+
@r5076
NACCGGTCTGCCTGCAAACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGACNGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTNTTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGNCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCNGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATT
+
*>BB#>15:&>A=G18#$)@+-<DD0?CC3*G>=<.G>"HH;9<-+4<<(H)H7*:)EHF,$&&>C16'>1857/:HH!E4?,H0D"%?1;/;5:(H1+CG098*'($*A=*7=<;(D0.=9>D)?H/0-'&4"#/;$!19>F.2)D%4#)E3!5H'))F@*)$G)-H8<(2$:G./":8-&BH#+G)&<;-;3,-'!;7<AG31A76F-2409A#("4G>7+2#,=?-G9H9@<'+')3H1DCH"F@,6+8/'2=,#?9(A'7=7.@638":5$BC4)8/-EG+F;3AC>H??&C5-(17$D)A0;='9(DF=3/9F&D$B/GE9
@r5077
GAAAATGATTATCAAGCCCTGAANCNGGACATGGTACGAGCTAAAAGATTCGANACCGGCTCTTGTTCTGAGTCATGC
+
608"@27.#GA<6B+$F7=3%>,=-:B@A6,<$94%D3+<$3C"#<!2:<H9F24@0-<:*EF=:),97F9;*#!0A&
@r5078
GGCTATTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATCTGTTTTGGTAAAGAGAAACGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGNTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGNGATNACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTT
+
1DB:4G+2-#"H"&/6:2E01(&'34:9"(8(2-$/43A2A#40,>G(1F"+(#-8(,E+3;?+E0>48;D6991<""5H?6:H!!.!%E*!/1(1$1*<2@G>C7E@A'?1?-D&>38,9GD940;3'6HBG(>18=@+4E-:#!HFC"!,))1:,*D)/1<HEC1<>+/E3?*@9C<!2H:&$%0-8-$E-'.&E!#;F54&8F.'-9*+/AG5:A14,=*)HB$'78B$63*>-9%DE9='*""B?0G.3F7A"$3@><,G746<*H$;(+H);,3,F-74(63/75==2)C,?G5-GB+D&1E%%4E8$+=1A8>"&+592$!H@*=40?:E5#':(0?#0*-,'F44:H;05>D!+'(**GG@.$220+"H7AA8D/H5#1)2=73/H%1()9;F@/'>2D=13E<>G=1C$&4D"'%9-9G9(A>/%:86"7%0B:?/-55"DD
@r5079
CTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCTTCCTGCGCATCCGGATATTAAA
+
+)H7&,%>69)74C8:8,F91G1@7%'=D<)2&0%6962@B3B'%B.169E!9$@22:D2!.A/<200!.(GBG,087A4/1GE&#"-3=7HBA"8H9::1H"&$B:HC$3%("70<&H,.FH)$8"=+>@?-;@B&"$C41,7?**=,:&BC2-7BH
@r5080
TGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGCAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAA
+
?#@:D2CBF$%F+G.?)C%8AD<54#8>B-F/7<%D(<<F+""<$>4**$F/'$GA;">>@-/)=<$=!+$:CEE-F$=B>A=)"=<9)(.:8:7/6"!:)%8&%&480&5G'0H9H@FFBF'DG/G/F48G=;26)4G8;)8)$0</?4H"7:*>:"-=
@r5081
CGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAANTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTNCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGNAAGAGGAGCTTGATGACACGGATGAACCTGCCGGTCAGGAC
+
-&676"A.=EH952D5"?/=8((7H0-/$F:#:"#8@HDH?H,:%7F@,D5*"G32#F!9#+441-7%?G!(/:(61$&.*DD-A.A?B"#6$E759E-B7E"*-CEB>5(3/"8)4-%!"A;5,EB4,:@G0$,:1F"A'0<)&"@:@+<8>><$%,#B?=)';672*D10F&#5"!*"HGE#%8E'+*>;BHF7G&1)=>'2==AF!"G"'%-D+8!/,(<&/#A59.":7A95D!602$&D:E/,&9-9C?<(A&6$%+1A??*&<H/.48$E,0H6
@r5082
GCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCGTGCGATTNCCAGCATGCNTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTNCATCGNGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCNGTGCCATTTTAGCCGCGGCCTGTTTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACA
+
+FC0@/8?5F29:$;!1=:94B&#!#9791$$;>6&5+0C?2E9H*+64H9!BFC&<2G?%;9A,+82!+"$A>1>98@H3(<C+><&/<8#&))1D33EE8:%G;<B3D/%10;@;1D-E+HG?H##,0'0C>)+<)8%0G9/<1(59:30*%C+G>>C%(+"DF->D?.1.A5-B1C4%%+%>!H,8"H7EH>=!4A$E/!?.E:;<+&G,#4+(000&;3<#/53H#$,2410.8"C?D2+%(F<1<)H!1E'+,D))F3.@E1=>8)2&/&AA=1<D)/+.#%H1G6=?.H+)#:"A2F>7)6(19+80;90'B;=5#.49238F*0)?)*5F+H"#%H:9D0,
@r5083
TGGTCTAAGCTGCGGTCGCTTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATG
+
+'#'*)")*#("*$'&'&*#!&%#')()(&*$(%')$!()'("&%'&#)$$)+%!)("#!"#(%$&*$$'!"&$!'(&+")"!"%)$$)'&'&#''$&""!!+''!+$(*#%!+%%+&&)$+*)'*#'"%+!*$%)(('##$!+)#'%($)#!''&!#')+#""'('+!&#&!)+!%"+(%'""*)*#$))#(&!'(
@r5084
TAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTNCAGTATATCACTTTTCATTCTTGCGTA
+
%?<;&=%8!4*C&1A3#*:.:4F709+,6'!186-=+%*B?'66CE76E86AG78E>3F3)*7C015(/,&B/%2+C.C'<8'));:,7>=49@6#0##E-!3"6*#@F.&F,::&4-2?/!?-/BC02':9+7A+03@-3(:$F7
@r5085
GGGNTGAATGGCTCTCCATTCCATTCTCCTNTGACTCNGAAGTG
+
"")&('+($###%#"$$&&"&)%'#%*"+#+%#%%$)""$'$!(
@r5086
GTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGNCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGA
+
3>H(9E@G:@(#A9@$)A4-'H?##"*H>>$@C=DG?:G50/3H#+E#58$(9E402+==0(ACC!58;5G08&C5C0..9:G52+14==C#/=EH%15180'3*.!:#9!8>'+E5&G*?F->E>!#;09/-+5;#%?5'6B;5@+7:%:4!.AD$,"3*@'&2:9/(/503,F/
@r5087
CGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAA
+
3C'@<"3:E@;G0+4!C462A%5D'@&-FEC$<'-D09(8)$2E=!)@4E49/4?F9E=389G(DG8<-:+1")C#GC<G1DF*F./-D,78+%91B4@3)?;?:@9F),7+3?<98:9&C-9=<AD%F<?8F#F.%?2C3E6343$$"/9%,G@F'D.C0?13@@!;F-/2C7FC5F)>C8'<C;H8+%!(##D2A.;/@3?@%%%E@CE(,H=CD93#G,13*/%)D=!!F,%A21#)";G+7A9";)$)A.;<*B(/AH0;!AB+&"9.B
@r5088
CAANNTCTGNAAGNGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCAGCGGCATTGTAGGATTTGGTACAG
+
()'#!)()$"'*&"+$%&$"'*'!+!%&(%+"#"#*(%$'!)#$)+#(!)#*&**#&")+(+*$(&"(!!)#&&%!'+#)**)#"$)*("#$$$%(+%"
@r5089
AGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCTGGAGAGGATGAATGACGCGAC
+
,15'E!8!CD0><G+$;71&9E:"<>86&?<&B@(.%.A)=?91<9<4H'@>)8:B?;%-?,0F;E!8);"5158@C*@#+>@
@r5090
TGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACNCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGNTNGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTNTGGTANGTATGAGTTTGTGGTGAATAATGCCCCTGA
+
:C5B78-.-5A6)!G),,63/DA92F,HB6/CA9%=(/$C,*$='.C0=.8'(/)G=6D:4'.324"B?>C6/=6)6@5?D<93=@C7B?@&2:E)%5:'"B#06"%/8>!11F?D.E,5!!?'F#3628"2?)1H28<<)9;E73;B@8:.*C&+&/G')D:)H.60*E*:06#-BDBAG:@":'AHA8<6D:H2EH&)F'(=04%'-1A73G4@.!4+#<@1>AE'C.>23<4E$H9@?%;656&00$!)2-A!&/E"=A$*%,A!GE3/4'&-<7810@&CH@%&G5?<6>!BG/'%0HF+E((.C37F+@E6;,4E<-
@r5091
AATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCNACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTNAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCANTACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTNATTCTGAACTAAAACGTCACAACGTCTCACATTANATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAANACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGT
+
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
@r5092
CGGTGAAGAGNTTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGNGTGNAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACGCCACGCTCGGT
+
:F,F.3D&=%:&;,%@-)5(=)G0&#$-;4>!D6=:@<-72*,?!=C(A:;(.&E33*102)9.2=1D?F7C"HG,"1$<.*;<6*-)96):F<*0&1?60'*).:<8?<&7BABF-*513?923!+499%%)F)'3'85%H?GA915;$+
@r5093
TNCAATANCCCGTGCAATNNTNCTGNCATCNTGCCACCGNANAAAATAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAA
+
""$(!)&"#(%()'*(*$#$*%$))#&$&($"#(')!)#&)$")&&$+"'$%"!#"'!##"*#'""#+#'"*"#+*&#%+#()$!()"'""#+"!"')($$***($&&$*+#"*#"#(!%%&)*"*%$(%'#&()%$+)"%))(+
@r5094
GAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCGATCACAAGCCGGATTCGGTATGGCTGCATNCTGCGGTAAGCACGAACTCAGCC
+
E;'<03;,(B6=59"*,H4C(?093=HAA#;'=.-0",,:>"0GG+C8=/%%:9D<B26&(&A/>@/#":/?'GA36E-9E@/0CB!;<7G#6!82?3%C><B3-(-386-"!7;GF(B8/@,3AD+H:FA)"6-63''.5G6C08D$).0/B%@E;8HB"5/*(E#.*B#&#7"941F+&B$*"$6<
@r5095
GACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGC
+
C:@A=&#)7)<#'B0G62*$C)>?5)"'?=6*7E3H3"&(!-
@r5096
CCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTAC
+
B2E>$0061CB=/?B;G"1-(@&C@.!9.'5D(&(*/B.F1-%9B%D0G):;1@'!1!-H&"D!#&&C/@)E-B'
@r5097
NAGTGNTGCGAAAATAACAGCGGCAGNCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCT
+
$(*&%$F1&"+(,8F3;B4!'3$0(E4+?9##*GH*07*2'')$-!&=(-!0%&2'F)(E'."G62$9>B'FH2*>5,4D6'A>E?30<C*0=?+==5F0'8>?)4-1)70$-'*B7%8#G%E3G9=8"B"H5A25+4;??;*,1'GD/F)8#(%*76FB;9'6&#(6!-C
@r5098
AATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGNATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCCGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCNGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAATAAGTGCAGCCACGCAGACCTTTGATGGTATTGCNCAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGG
+
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
@r5099
AGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCC
+
/,'C@&C!B+A9717/=7(#79F+9B1+31,F)2@C7<64
@r5100
AGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATNACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGNTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCC
+
#9#<5-./3>8G(8:C34E((90F)D4>G2=9&#B?C0-$7(B'%"F)0,+H".!D<@3:,,>!:D2C37,?-=G"!#=!G,.6)$>?/H;4+/&:34<&8BC63!A@*4E3GC8$$G2>&G=09#A)'-9=!$+,@3C)C>:GCA8A=/<9&&D<%:26!1*#:"A>1%:?+FE*!/701,H%(#!E33H9G@8>CEG&38?*%89&$$9,4*$&8%//F/?2C&6+%B,%$608%3!BD98/.33/=!,0G'#1F79?+C#(>'17'G17>3<.9=6?@-=..G6A/=A.$?F0<*)0/7<>)3E8A5*1?$4,AF):G=/+>;B3"&D-3%8B(6C8FB+*H77/B!H7);+$"(+-@3*)H?E7:C=H7*<+->
@r5101
TCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCCTCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGANCCGGCGCCAAATATGAGCCAGCGGGCATTGTTCACCGT
+
:,9&H*@6&%2@#$:A;&:#=.0%"C&4(,1G+0077&>H.-;40>*3;$5B*B;#;>-4*$8C(/*,&.--A5;C9,3":%@D&2?'$G7*&-&;/$?A2;5E8<@4810D"D+/7B<'"4-E?/#0H.F#9.5'>-5<+4H>?1)<@E6H</9.3
@r5102
GTNNATGCATTTATTTGCATACATTCAATCANTTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGNAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGNCAAGTTGCTGCGATNCTGACCAATAAAAAACGCCCGGCGGCA
+
)&")+'+$("')%'"$')"#%$'''#"*'#&"%%&'&('*)*&)!*"()((*($!&&$')#!*")(+*'&'#%+&!''")+'")"+)"'$+%##"')$)&%)'()+))%*"*')('$)&#)+$#&(#$)+'!"%'$#$!&+""%!#"%%#%)$&'&%#'#$%&*%"#"'#$&#$"%)&(%+%&%+')")+*%&!'(*)#()(!)!!!#*%)))'+"!*'$&")%!#*$#$)')'($#"%$%+'%++**&*&&)%(#'$!!"$!($)*&#)"!&*'(*%)!*!&))*+$$+"!!&$))*(*#&(%#%!+"*""#')
@r5103
ATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTT
+
/D95='@$:#+2<*2:"$(!#6&0G0'G&$+7#-G;?$</%1DD97B&8#&0D#?>/;FH'<H&;CF?FEG494D(0CA<8
@r5104
CGTGAAGGTGTCTGCGGGCGATCGTCAGGAANACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATACCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGG
+
-,<$&?:704E?H*C5E7!*-:)5648<1=!97">B1E-C725>B=A@E<+%,DC,E<9B-,+>7(,5BB8%,9,:,F287G4:15@&&9)(#!<GB+;?&.>*8<&@)'84/+),E,)%#,)<)4=A=-1,E#?.
@r5105
TCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATG
+
B=/H*''231"'<!>H."2"())FB22&=.E8**0!-7""39#%6!%:H)G:C.F4$.#-D0E/5?-5,B,>8.)A2G"58%D&"+!A2B*#&>6"*DC+7).C1/&6'G$#$>&<+?(01#.7D-142$B&$'-D23)69+$0;<;'4:2!!7*C&(%:A-E:#/.3D)<$<G6D@2"C3==:9-<@<A>
@r5106
CGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCGGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACAGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTACCTGGGGGAACTGCGACTGGATAGG
+
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
@r5107
GANTNATGATAGAACAANTCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTATCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAGAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGNCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCG
+
&"))!"(&('+##!!'+!"%+!#")((")$%#))*('%'$"))$&%*%"(#'$%#*#+&'")($*$!#%&#%+&%(!$!*&*(#!"&(%*$"%"!%$((#+&&(+&#(()"#&)&("!##$)+)%&)"&!''(+)#+#"()(#('$((#$(&))(&%##!"#%*&#)(*!%)'#))(&)(("'%+)&()&!%)+'(*#*+""#(()#"'#)&*!$!"
@r5108
NGTCTANNCGTTGCNAGTTNCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTNACTGGTTTTGCGCTTACCCCAACCANCAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTGTCTGCGCGACGTNCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGNACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACATACCCCAAAGCCTACTGCTTTGAATGCTGCCCTTCTTCAGTGCTTAATTTTTAGGAGCGTCACCTTCATGGTGGNCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATACTTNATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTANGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTANTTATTTTTCAANAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTNAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTGATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTCTCATGTAGCCGCNTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAANACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAAT
+
#(#'##$!(#(#$#()+'")%$(#&!(*()")+%)'*&$"&#'!**&*#""+'&*'$(+#$""$%(&"&%*$%**)$(&#$*$$%%*(+&"+'*!&'!$$+'%"#'&+()(#&%)!*'!'#%!!*(+'+'(#$)#"&(!##)+&%(')(%%#"&"$(!&"(+**$"'&'$%*&)+*&+!%(*#)$'%")'')**%)%$"*&*#&*"+%!&'"'!(%)+%(!#)(*$&+)'%(!#)+&(%&"#("!)"+'$!$%&(+*'+'((&($))#"'(%'+'*"*!!*%&(*'#"$#&"%'!!!(#%%$"##*$##!!#%$$)#&+$'$!+#*)#$*&$)'%*)+%*")&**$&"(+"!"**%)#*+)$%'%)$$'(&#!)!'#&)%*#)(!($)#$!*$"%#&#(*"!)("+''%*'#*##)+$'*+)(*)+!%$*)%'$&&!*'+%)%+%#*!($%%#"+'"!#&&#$$&!#**())#(!"#"))#%)))('($)($)"*''*(*!+%'(!%+))$&('(#)+$$"'+%(+*+&''*)%$"+&#)+*$+'((%+++(#"&#%+*)((*)&$$$*'+*+(%'"+&!&$"+&(+))('+(%(&$&('*"""$))&)*+'&+&##"+!&)&!#'%&$+'*"*)*$'#%+%+$$$!*!$)'#("()&!(#!(*"&#&$%'$&&&($)*$('"'%(%+)&(&!''+(+#(&"'&$%"++###+"(((%((!*#%)+%))$"*$%"($)$*$!&&+''")''$)*#+&*$')+$!*(!*'&((%)%'%(!#'#((#"#+*&)$*((+&&##+'$*&)""&('&&*$(('!&$'+("!'*(("(*+)*$%"$$"(%**(&$&(!!(!'*"*&!'&)++*#$!(+$($!%+*)&'('!!$&('#&!+!%'+%%+'+
@r5109
CAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCANAACNTGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAANACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTGTTCTGTAAGG
+
+=D,C((.DBB>G?BG=B2H<#8:+?(>A#=.D'@94HB?#':%,E$'F38<G$3A0*"$AH<C";<>CGB@D1/7-#13!:5+7<<4)57B,>-B"=G427'7!&+",,$HG*F6-70+2B@<!):3$,+=#&C>+&'$(28/)>#;**=4>$+1<>>1-?.H+(/H>B.)?H',9,<)/#;$&E5+=GA!'?2=;9/@5=H9+#4!8;&"@%%EG1A75C,9F6E+G(BH28#61>5.$&729H)*8+&19>5E=,4EA!FA4?C@?3!845'#$4;F=A4@*D7('-320&E?($C!=>=#<%B-6A3;"90/?<49&:@8E%?AAH+E6!
@r5110
CGGAGCTAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTG
+
%7F.#4E/'<'%7$6(G&55<2%?BG9A%%:.6050>.$:&()"+%0'D4F,4;&#%&!A%/:F/=)657B";GE"7"836-*$7C+D!#402CF@")4-6D@'+'C0G.:G&/BF"B&&G+5<+.@B*<8=4.472@)#!95))@@?A4;)#AG3&F!2!#+'(3@H+D8-;?+8%B1F6,:"/(+)A/"?05A3.9E*A"'(D4F+
@r5111
TCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGNTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCA
+
4";DD"'%F:?&>29+**0*))07=D3<(#:4HE?6',)E(H):B$+8!>?B&)906-:=:F04$)F%4)&D!.3<G9735%:+02G*4#)'=69>,+.!9+3:+296#@25)8A7??%9?7=47.B@4H7"39;58>996:/BH>12$+0*B0"::-.1%87".F805>G>?2?*8'@)2(H7<-6:*CD?;=64!BD(:.E>>((F&E*AH96%)9#%H,;&<>D:?99C@=92CE$*C":3:A%3#'>&
@r5112
GCCANGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCNGCTTCACCCGTTCCGTGCTGTCCANGATGACAGAAATTCTGCCTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTNGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGNAAC
+
0/A509F+=./A*7#60!/GA'(7.4'2@#@,BB'!'('!%8*7C2C1-@27FA":&4F2@3D:?514);%)2793?D%?3'90H;<-B%?2"%?83+4.:A)?F9<&H;+$A5'%2+.4.03$&?9(?*/?!2:7+;%4-05+3-H?;:+?<@,F5*;4#H>6/)C,4D8"D+DD#0=/"!3$#3#':,9@8H$'>?%#@!+"@7@%72&+3D6/EA3@ADC7+D*,=9'$>%1D.38,?8=-/2'49<C>3$,2?$.=*.-*B+F(.&E!25
@r5113
CTGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTNTGTTTGTCAGGTCGAGTTATGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACCTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCNGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCANCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCNGTTTCACCACAGAAAGGTCGTNTTCTGGCTGGTCAGANGATTCGCCAGAATGCTCNGACGAATAATCTTTTCTT
+
*+#$)%*!*%$%(+')!'($%%*%+!(*(&'##'&+%%#$*$&&&**+()"$$*%)(("%%%)*+'("*$'*+%%#*"#!&++!#(%("'!$*!)+)+(&"%&*)'*("!&#"*$*'!('**"!%&%'&)#'+($)*%!%"*&$"'%)!$&$"#*$'("+*'+%""#''!*!"%"!+$+%*%%$)*%#++&&#$#+%+$#)"'')(!*$+'!%*()))*))%()(*'&("("""$)'&("*#&'(##"$*'!("+""#++$*%'#&$!!'&!%*+#()%!%#*"*++'!+$!"+%""(!$!)(%+(&*'!)!"!&')'")+(""%#&")*+%&&!$&#)&!"+'%'(%)%$!+&%&!!"((")#$(*%&*!)&)(+"'&+#(*!(#%&#$#&+))&!*!)&(('(#%((+'%'%$"!(!!)%#)%))%'&%&(%###%)")*$#&+**$!'
@r5114
CCGCTGTAACGGTCNGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTNTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTGGTTCTCACGGATACTCACGCNGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCNTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCNGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCNTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACG
+
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
@r5115
NGNANCNNNTTGAGGCCAAACGGNGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAATATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCCTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCCTTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTNATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCANCGCATTCATGATGGCCCGCTGAAA
+
%%$&&%$!$*++#$"+&+$$!)"!)++*$"#)%%!*$$&)'$(!&#&*'&%'+%"+'+#)%)+"%+("$'"'$'!*+%'#(#!*!")!''#)!$#"'##('+'%&+$+%#+%#$**+'((%"$!"!'*&((#"++&*((&)"*'$(*!"&$$#+!&"&"%!%)''%$+'%&+))+('+(&$(!*$*(%+(%#"*&)'&(!!%!"%('*$"##%"'(*')"$'+("$+%!(%*)(#)*"!*+&$')((#$!'))+$*$"(*))#'!"%#(*#(()'(!&%*'+&#$&!(((!!%($##&('*))#"*"#$(+))#!$('&"%&%'$'&)#"!"#*%%"*)("!$*#"*&*&')'&!%!!)'%$&'#)")!)+#!#+'+%#%*&'*$&!&(!(*!()$$+&%'+*'"$+**$$)&"#*&#""%$#""++!#*&$#&"#%$(+)"$$('&*)"#+*#'()(#&(+!*"")''%"$&*+##)%#$$(#++'*$$))"))*"'**'!('")$+!%$"(+*#+$#")')+(+#&*+"(%'(&!)*$''#"!#!*+#)!)"++#(%"*%+#'$('&"#!#'+#$%&%(()!%$&**+&!%!&+%%$()!"#!&%%*'")+)'$+(+&"#*')&
@r5116
GTTTATGCGCTGGCGGCGCTGCGCGTCACTATTTCCCGCTGGCAGCTGGATCNCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGA
+
)A+619*?#"%G:C.<&.1G5CBH3&4!B>:C-?697#$/"FE+6)8E4%<:186),*E'!!(.@)'(5@@FA%1C;*2E(1?9*B"C71!2"!>3F9%=)B3$2&F,;,,6@D3>(-$,/)(.$EHB.&0E32D4.=C+-@AC/GD-#
@r5117
AGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACT
+
G7*?(&7?<-F*"G!+%38EH2,+7%?FG(&*48CF(C991,#D/@6371&6<;.0%"368!1'-'CH;>/#47#/(4
@r5118
GGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGGCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCAGTTTC
+
(7:F.13A/D.)6*-88-.G<7:D7/40;AD**;)2'G5B"D%!<#-,0772=?)62!3.&EB3.&B*,6*/373&5*)F0:8E).E+"E(F%9<4G>.*E"?)='<.7!3=0CF-C"*>94+.7%/6D;B$=:)'<"262&+/+3)'(8>"<<D3;2CC.!$-;!8;:777B2+(8,$8""@D0;1?=)%HH6:HH0".829)3.@7.3
@r5119
CAGGAGGAGTCCGGTNTGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGC
+
<B@&:.)3<>!B3,@'9/)*&-=-/H">8)!D*5#($.54#"/0#;)<9635:=&(6*1*H:9<:HA(28!&0E+?/@-
@r5120
CNATTTAAGGTGATATATNGAAGAANAATTTGAAGAGTTCGAAG
+
$)@;2>'.)"5E/2'E%&741=(2(F'?HH;63*%A!6A?))E-
@r5121
TAAGCNGTTAATTTTATCACCTCTAAAATATATCAGCATC
+
(('#$&+*$+**!$!+%&&)"($+"$!"##&(&*%'%*")
@r5122
TTGGTGAAGGTGACNCATATATTCCCNCTCATACCGGTCTGCCTGCANACAGTACCGATATTGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCNACAGTGATGAGGCATTGTGGCATCTCGTTGAANACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTNATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAAT
+
D0$)*/D='6..!:<>;1"5%(=G26G7"$AG%6#&$C%+!))'D>2$<-<59+!?-9$:4317<+>A<50ABB@##;6F$;H=DF,-F&"5E$*1*A8#7(D;');&:*F6064+90;C**)?'4!=&#?8(G7(A+G'-(1'(7*7A3?4:=<D!!32#H@4==+0@54+B">;:7*@@@</#G00<$A$5A?.*>@B5,A<+;!?G5(#5'0@&31D9.#+6C=(A+3+!A"$E3=?>
@r5123
GGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGNAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAATANCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTNCAGNTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAANGTCTGAAAATTGAGGTGACGAGTTAAACATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATNCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTNGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCNTCAGTGGCTCTATCTGAACGCGTTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAANTCTGTCAGANCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTNTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACT
+
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
@r5124
TCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAANGAGTTGAAATTTAATATTGTTAATATTTATTAATGTATGTCAGGTGNGATGAATCGTCATTGTATTCCCGGATTAACTATGT
+
/$+D(7=B)))B/9;7HB%0@B-D&)&G0.#+@@-%708.@AC>,D11?CE-:F;6;5#@FH-(F71;<:3@,.D+67E&+->&H!'29'@/C$C028HB5)1.AB85.H0)"7@>E$.7#79//:0@$A1,-32B6D<;1?G"G-:2GA*.@D-=&+1>-%<-1$.:E1):;50?-E4<?."-2F"G4E2E-=1,F6%$@F+/4!>2G,.G&?
@r5125
GGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGAGATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGC
+
>G7-&6);&)5).F&F#..45&:"E;"'-D!?+E9!+-#DG*$(/>5/"F.B#("59&A4%32A=B').9,,!<+4/,*G,G-(0&7#3HD2G2EC!4$0;<$$&$%3)C;B@-)7@(H#=%.<!.#AB1%;3@/#/5226:DCC%9G?6$+'6=93H-!D(<F*G;0-06G&F&-(F(*;,3?BA0A=(:!:/F"AB-&2H'04$=>3+),&4+<6$-?F%E*(EF@13AB(?%&'!$704>.D:)!G1-#>BCB58E"'#4-C,79$%7;5+F9*"'36$CA!08E@>D
@r5126
GGCGGCGTGATTCGGCACTGANGAACCAAAACAGCACAGCAGCACATCGCCCGNCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTNCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGC
+
)0E)27.$#&D2+?<!-=,*(0;$->G"6;>&3.(,!.8(1B8<7')H,8D!9(12'11E8%&(34=5=6>$$8F7;'CHG7(0;';!*@216,)283%2*7-+798;867>%/4/CE3-:%C5>-0=:HA@9;<@5+7G3<A30.?=$9#G$*1@9>2(,2F<'90$!:5<7:,?3F=2>703+>
@r5127
AGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCAGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGAAATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAG
+
9F6*B(C!6(HH(0@7F/C%8;0*F+>0#<#9)GE+>D"DG*@-,*7/,+'$)"/HGD,(=9#EC1./9:D?1D@9/;3(B#:,B4;C9/+-3*1#)9%;HGH3B7<$*"G,@:@@<F+D2(*HB6)"!!CBF5)1#'<178=G?*?7E4F588*#,;=#":F@FG)9>72-D0"+;BE?$GF!")A46E@(74<2"1,:36=GC2),,F6=8,)D0*5H">8C==#->@78>+=CC<E*'FC7F+:@1/EG.!8$48!#5$9!HGG+4A8$1F7=B%0/'+$B;5>GC
@r5128
TCTATTATTTTCAGAGAAAAAATATTNATTGTTTTCTGGGATGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCC
+
(9=-?=B=B62-9:1;-++%116%);2F&28DC!&.</A9)(5/7*C=(>:B;3:>B;7E>12##@5#(#3(9."F"4$,'G.!E"$?05A:1@<
@r5129
NCANGNATGAANATNNNNATGAACGATGCAGAGGCAATGCCGA
+
()($'%($'$*!)&!!%)))+##**(*(!!)'*#$%"$*%+&$
@r5130
CGCCTGCGACCGNCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCNAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATNCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGATAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGNCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCCTCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTNTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCC
+
=!FA05/?#G$F6;?+D#2/B/2AC4/H!#B'@":@@>(36$9H&1F98%#F)!?H&=210,,>'+'5H'$DB0!31?-13@4-10?6;76'#F/7/B83$C-?0A,A$4&BD.)&93.8H)$69.?22#&60,'8@7.,'-?934EH/-&E>-,%(.:@?.@57GD<H1"3>!-6/4%,BD*2F#*4&G'@-2=A#0EF;B9$'9">4'/=<4+$B,(:&09#<4C092"+D<#0<1+8>;6%.F6$'%;$F%;C:05**EC5!A>D)',6>F;/6#!6&$2;<-4E1C$"C>')AE*=1'=<F*=*:&):9=4&A7!03G5+C+6GE7(#1(BG'$!2#=:G$,@.5="E%/*1$"D)144;*@20036A-':2F/#+:F,<4?;D9"1$CB3(,&5=#,"-7@.5/4562%8020)E/#(10G113);*:,C4,:+C:2(G57B1>8EE'8*A&BH<&?%">%7<D=".'B>3>:$=,(-+;(9'D+&FH.<+,9-5+%646*5G/"5(601+CA1?$BE&9+(C6@(0%22)>9#<GH06F*361!#'E(5+G=B5!5"%7'"++-)8=A#::5H@3$>=E4628:$F%(22-.16(*-%:>A4)-A93B891#0!>?6(HH"#$HH./E"@?GC89$E(*84==$>;*4(9C&#)?+063-87:A$H'/<8-93B%
@r5131
NNCTGCCNNTGNTTCNCTAGACTCGNTCTATCNGANCNGNCTGANNNTNNTCNNNAAANCGAGAANTNNAACNAAACNTNGNGNGNACTNCNAGCTNNCANNAAAACANGNNCTNNGNNCNNCTNNTNCNNNAAGCNTNGTTCGAGNCCANNGTNNNCNATNTNNGNTTGNNTTNNGNTAANTNNNGANNNNACCGAANNTCNNCTNNTNNACNNANNNGGGNCNNTNCGCNGCGNCGNAANNNNTTTTNGCNACGNGNANNCANCTTNTTGTCNNCATNNNCCNANGAANGNNCGNNGACNNTT
+
$"$$$#"$!!!#$"$"#"#$#####!"##"#"!#$!$"$!!!$"$!!$!!###!!$$$#$"!!$"!!!""""!##$!"!!$$!"$$#""!!"!"!"!#$$$!$#"$!#"##!"$!#"$#"!$!!!""!!!!!"#"#"!#"!!$"!"##!!!!$!#$"#!$"!#""!"$$"!"!""$$"""!"$"###!$!!"$!!"#$#"!$#"""$!#$$##$!$!!!!$!"!"$!$$"$"##!$!###!$$!!#$#"##"!#""##"#!##"#$$!!"$$##!""!$"!!#""#""""!"#!$!!$#$#!##$
@r5132
TAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCT
+
H3/9#1%"C".1!2+-);A*E!HHA/7%-17<*9-//!G3'H:0"17,F=17G!G#+%!E'=B17.9<+.0%>!6;!%&%:A#=3$$'*23?#DA*)09-&B0+:5%:@C"!#/''$'*>2(:!0+:$7.2CB4A@9.*#1@G91%5>E#G77-*CDD2H)GDF2E%+A2=H3(CG8%"-,%G;'EEA!CG83<.9>C8>=!=:AA*H<-'2C%%;</2,1-)(H81(97'%5!%);;$#'8A"99+=65"6;9H0<0=,!-2(@!C6-?#C/,#,C73.,%&3")FHAH)&"G/%=1->C,:37
@r5133
TCACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTCTTCGTTTATGCGCTGGCGGCG
+
%2"+%:?<*83/,4B%G.1H$&G9H3<1'F?1-2C-&&/8D4.2E>+'%&70F7;2D,,H<"D394">4EGA3+)D
@r5134
CCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTC
+
B@<3$-E:D'=2+F%><=4860E;F<8CA+E.D!5;GC#=6;@*+D$H2:D7@+7B&<+,@.$F4<>0++G;&2H/"$3,44BG#;C2+5-+?D*)H)GA6'GF@E%:G-D;7'0<7&(1'<>@
@r5135
GGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAANGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCGACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGCCTTTC
+
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
@r5136
GNTGTTCNNTTCTGCNCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGNCCAGCAGGCACTCGCGACGCTGGCNTTATCCGGTGATGATGACGG
+
$&""*%##)&*&'*##'+((*("##%*+*('$#%*('!#)!(%'&#&*$+!))+)#%&(!*!(&&*&&!)%"&*)!)(%+!'+((+*+*$*!()#)+(#$+'(**#*"")$$&'$$+#"%+!%
@r5137
TAATGNTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCTGTACTACTGGGGAATGAGTTGCAATNATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGNTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTNCGCCAACGACATCTACTAATCGTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGANATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGNCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTAACTACTCTCATACAACCAATAAATGCTGAAATGAATTNTAAGCGGAGATCGNCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATNGTGTACCTNTTGCTGGGTCAGGTTGTTCTNTAGGAGGAGCAAAAGNATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCAT
+
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
@r5138
GGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAACTCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGNAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCTTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGG
+
$C=B3.$>(F%F6?+(4=1D#C0A'."-0>8<=?-!;#55=H*,F1<E3-,C:<%#$.5F36:"2C5(+-%%""G)@AH=E4=CAE<,;(*C"(:$978#F)B*<5*>(D.:+1:G$>33,6*1.'@!$H'>4.E+4E,A@40H;3=!5"B1E?D,&(3(3:'.E9.5#'-3?84%,37?<$30C$B@HHF'(:3#&;55:2@/H$?:<H;B;:H6(<'AFD./8%(F4?>46:<&=%2?-%55C@G)&*9AE0)#@->ED#GF*+702"(D,H0(D;!(&9?<8-,"=D6@D4-/E!2/3"G7-B8G:A,A=%5@')=5=?85,D@$5>31-'48=EA8C%,A*<05.&<D2(4#8GG*5G4#$+,0=?6@-@>12:**/
@r5139
TCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCNANTTCACCTACACN
+
,A-D@)EB+D+!7CH7A?/F/G:=*3,=;63G'.?#H07/>G*%1!"$8H+D8=6E1&0C>:H+HA#EB81F$1
@r5140
GACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCG
+
6@B9;:C48;.&4$2BCH?,%E'G=&>C;$.@!>08*-C*>H6"4DF)@*('+(B&"2"EFHF!@E=@<?7#3E84+<2+<*@<F(E'.<?5=A175:?;93*@)4=
@r5141
GAATCCGCATACCAGGAANGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATTAATGCGATGGG
+
+7E8(-GD9=4BBD@1;9?#FA$9A'2>E8,3<,>'1/A/<(4D<2/-B&!1.*0!E'@:"5(',F3>
@r5142
GTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATNCCTGCAGTAGAAAAAAATAAGGCATTCCTNCGAGCAGATGGTTGGAATGACTATTCCTTT
+
0E#%C82D:A6;6E9!#2$+G8CE'E>'H;$!,/4'(+@E"E5;>17/+E#,F%8A:25(1$#;E5G%G#:14;E$)69H-B1/D<(G>=87(9:G!?!E<8.D0F$:.>@,(7%>01D=.46&.C.C8!=B:C&D+;);&&G+(;8!4
@r5143
TAATATTCACATCGTGTTAGAANACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATATCGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGNCAGCACCGGGGCGTTGGNATAATGCAGTACGTGTACGCGNTAAACCCTGTGTGCATCGTTTTAATTATTCCC
+
-!</1-9<@D5599H67E+5,AHH>%!69F>H57H&6.GDA;;90G.G5,@4.?C;/C<8"3F,!?/>,(:%)H&"#"8%.1E$43!("F8CA'",?G378%-&-=(D7#@40;69>*#'-6E1G@)H8+?+?B#H%*AG6BAB<<<.G.#;5&859F8;2/'=364@(!A>4B*6,+3!6.@;3;8((5"8+.3(#@',CE79D=#,2>?72((*'1.9CH.2%'<7<F+6%;!01>.9$&4&',A.F8+/2>/0:&C:*%B$9E(A.G'5*9*7/03*?=8C5-<!$A"31B'8=8!5="HFD74!$-C3A1(5BD("4*=C;06;5?>##B9:3,3$<;3A.'9#,/(=21-DH46-DG0(8C:9$.0*7',/=4/;=?1'
@r5144
ACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTTCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTNTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGNTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCANCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCNTCATCGCCATNGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTNCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCA
+
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
@r5145
TTTTTTGTCTGTCCTATNTCACCACAAAATGGACAGTTTTCACCTGATGAAACAAGCATGTCATCNTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCNTAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTNTNGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGNGCTTAATANTCTATATTGTTG
+
59AHG8$>25("848";9@-E6)>/>&E3>(BEB>E0...2B)%D8H-"0?#8(C@"?-5@,/A!5D@=B+82B-,95*':04@)+B2%F81'8D577/B9')EF0"H+GD3(6*8#*=#AB/F8",:'06.,H#6;;>,D);>.:7F:<%&:'CF>+&@:G-$CF5H(>0/!G@#"+!1#:;00'=&E54D8B39;7#58*GG2>,3/6,H!@'$G8C8/3&)8683<6
@r5146
ACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCNAGATAANAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTAAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTNGAATGCCCGGCGAACTGNAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAANTCTTTCGTAAAAGTTATAAGGAANTATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTNTTGAAGCAAATCTGAAACCTATTATNGATTTGAATGACTTCNCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTANAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAGNAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTNGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAANAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAANAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCACTTGAATTTGAATCAATTCCTCCAAACCGCAAAAACAGT
+
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
@r5147
TTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGC
+
(=+"$H38D/C1+;%G<D1/B4+3+E>8,+&C$*7!G@G>A<+D',A(FEE4H'#&.25,';988G>-$";<2/9<!9>6HD;A$C&4FD0HH!6#(0).;78$>+!..$0%G
@r5148
TNGACACTGAATACGGGGCAACCTCATGTCAACGAAAAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAA
+
%!+!#'#$$$$(!"!$*!*+*($))++')"(*%'$#$)&#''"*')"$%*$"%##&!(&!(#$!&&$(+""*&'%!##%$&)!+*
@r5149
CTNCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGNCATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGTTTCTCTGGAGTGCGANAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTA
+
;9%/%)D,":D+;30F4@?$3#A19/!FA07/E!F**,13G41B0%H352,5:F,&"BD&!5$%@-(/60+1<.7E'5"-B:'=&0$A,%G$;2>3';)AF$48)DC96529#B?'-(G-?$/B6BE/>"!!$*$/;A=72.G2$H/1/3)<05=")34CD5D'<$-D#4&+43<-HF$!%!$.8DH*CD;4/,3D"?-H/0=<%0GB2H6#=A2E01DG'A64D527=.FG#9??75'-A2-0!<3HA)>?G,6G.C>A)>/3'";",#2
@r5150
NGNCNCCGCTGGCGNACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGNAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTAGC
+
%$#%!!&($'(*)&%+*)'(+#(*'*&'(%&*')#*'+'*#%+!!$()*')#%&'*(+"%!##!%'+!'"(*)()!(*%$"%+"$)%%$$%+#!&#$(%+(##%#(*#$&+&!)")((*#&&+"&#*"$&$$(+&$&&%!%(+$($*'
@r5151
ATCTGCCCGTTCGTGCCGTCGTTNTTAATCACCACATGGTTATTCT
+
C,#*0@"<2-+!C=224324*-<;=5*.3C<1*"+58"D:@&,,9(
@r5152
GATGGTGCCATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGATTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCNAACTTGGCTTCATTGCACCGTTTGACAGTTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTNTTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCGGCATATTTGATAGTCTGGNGTAACCATCATCGAGATCTGCCACATTACGCTCCT
+
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
@r5153
NTCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTNGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCNGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGNCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCT
+
&7&0B)6'5G32-7%,0)3E=&4H82H5?/52/H@*C<04%0B=$9-*765"<B18E"?1)3A"3##-.B>1)GF;#1'?9,;"DFC.G(@0"5'2(#.*7"39?6EG'"6&.0(*6)1)*:6!!!.7C/++==*;&9C@;*=?E'&)60B?>25-%B9@*.6C>2;E>4HF@+?B7;$6AD1.16+6>7'>,@A9.&B",=;A:%E8*G:'-@A><;(E:,';!<@,B,B!D*'0'>75"9!2E*2+B-=>
@r5154
TGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTG
+
H?#%@);E-G"E.8).2%%G?#&#12EA9"%AA"H2.#@6.+;<2#;7G'2<7-5#+35$(:'
@r5155
NGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATNAT
+
#.%F".'#D<$*F.*(<70HH-*H0=BB7'><,"A=(3A4)6,>@D4=H+/5D;)8F4,(*>/(A$''C/B1.(:14;DAD<(//3#E)<AC..*C=BHA6:-2.@::>B"A7F).D3,.=5>G0,=85-0?&67"A;&%&!"+?87A&%$%7":E46.:5H7?++F"3#-C&GE!)"35'1G';3A*%..EBF=$<F2F+#H"DE&!$B#(7F5"G?A?C?,"&.GA$/?/@,(7EA671'5*A7G!D9B.8
@r5156
ACAGANGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAANTGCATATGGTGTTGTG
+
)$$#*'+)##!%'!+)!("%'+#))!%"&($!!))&*#!$#+!("*&))&('+&&*)#))*)%&("#+'$'"#("+"*("&&$#!+("'&'$("!'%)&+"%"*'(#)"%&&(&&*"%''(')%$)"!+(**$!*$**$("'$$$)!$!""$'"+'
@r5157
CATCTGNNCTCACCAGNAAGTTNGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTNATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGNGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCT
+
&)*%((&#)(&%&"'*#%#%**#)+*'($(#%!+("#$&$($!$"!)"*('$$%&$&%)(+)+("&(&""%!$)'#$'%"%+$)*)!$$%(**##'$')*#+!#)%))!#+%&()**+#'+&'+$)*%&""+*%*%)%'*##!*)(+"$#)!&&&%$(&''!'&$("+&"$%%%&*)&("('##%*&)!!&!'"('(%(&$(&(*#(!*#"""%'#'%#**%%"&++(($!"!)%'"!%&'*#$#(%'+)((+"#*"**)(&*&!#*'%#$#"%)&!!(*#!('""('&#%$()+#!"&*$"+#%&('$#!"&+')&+(!&)+!'''#$)#()*$'!&$)#*$$%*"$!+&#$&+&$#%!%+%"$*'*''%(&#*'"##*$%"##%&%#(&)'++$)&%)*'+"%''!!!!*!#&)#**%%$*)#&%(&!$%"'(*!!%(%+($)(&%*#&"*+#+&(
@r5158
GCGGGTAAACAACCGAAGACTNCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCTGACTGAACTGACTCAGGTTGGCNGGGATATTCTGGCAAAAAAT
+
85'63,0G&&H::B!<1B#%@H;<(;>@4B6B0)52.9/66!#A7;-9B3+,*8#G2,@7,$&5$"!,2A>%"0D:@.1?<F74H?%:=:H"0:!*&8432@3(FB,(=;$EHH6:"&)E;*+@@$-"16!B2!=?)03+?D$'
@r5159
GNAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACC
+
!$+%'%))")#!$%$+"*%'#'+%&$*'$#+$&'*(($+#*'&$)%"+(#+(#("%+!&)*$#%$!)"#('(**'%$%'('&
@r5160
CTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGNCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATNCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTNGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGNAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGA
+
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
@r5161
CCGNATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTNCGGCGTAATGTTTNCNCCCGTTTTCTGGATNCGGTGAACNTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGNTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCAGGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAANACCTGCACCTGGACCTATCGC
+
("(&(%*$+'%!$")**!))!(")$#%%+%#")'$#"&)$#%$(&'%(#%#*!!+(("$+*)+%&$(#($!!'#$'&#$")%#%##('**$+#"(+#)+'%&#(##(($('#'+'!$"*$)%!$#)*#)+!)%!"**$*%+!"#(*&#!*%&#)+&%*&%'')"##&"#$*%$))'&"$+(*&""##!(**+""%&''*)"&($'!)+"#+'!&"'###%!"!!!(+'*(*$'%+$$#!)#!+*#(#&"%$+"(%*$+)"!%++&!'!!*&%+*$%%**%$'"!#"(#'!("%+$!(#!"&+*'((*"++)#!!''**!%)*(&+'!+&"$)($"""$%(&*(**#!+)#$+"##"!(%%!"*
@r5162
GTCGAGTTTTGGTTTGCTGGCTGTCANGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGNGGAGTTTGGCCGGGCTNAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCAGACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATNCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGT
+
+)!++#!''&$"""!$'(&+$+$'()+*)+()'!%$$!($$))+#+#$)%!%'#)"!$'('"$!&"$('))+(%*&'"*&)(&#)'+$*'%*!+%)'&+'*)+(*%''+)#*(&&*+%#&##)&+"(%&*%*+"&$*&**%+)&%!')##%!'#(")+%")'+#&$)+$)&&%*++$"&$(*+&'&#(!&"#&#*+*)%("*)*#+$#(#!!$!+%''*"$"%*&*##!))'+"*+**+#)(%&!+)&()$)$!'#$%$*#%#$***"%"#(%#"#)'+&)!(+**!&'+"
@r5163
GAATTTTTTACACGTATTGNCGCCGCTTCTGCCGCACTTTTGCTCTGCGATCCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCAGTCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATNTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTG
+
5>#>969B8$01)?6F5)/'B";*7;4.8+C='"F+>%308)9:)=C'(6#+<$:G.-62F/AE24%;"4#*+;6<1'?3.?.@@%F;7;,,<'0-;;4>&H04+;*CBH)&9;8$,C=?0?=5;73+<=H:(-E1)8+H5D*0(97:="F8&.?%9-5/E"3B-A<&/H-04;+%C<'&9:E!5=5(//=);/6,(D)B'*BDH%;D#?B62#+47;AE1&,CFD8>4%<5#'D5;57H->"-1'$1.<+7;<<4>;F3/A*'#--(HDH:96'*!=?A:CC8<C"98,?#C,1C81F*8<$6'"A;(!@)%)<D."%9>4190*4!)*&<F2C2&+)1.E3E7!5+8,GB/48FG'7.67+
@r5164
CAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATNGTGCCGGGAAGNAGCATCCGTTNCCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCNAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGNAAGTGTATGACNGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCNCAACCGTAACCAGCATAAANCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTNTACGGAGTGTCGCCAGAGNGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGAT
+
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
@r5165
CATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCANCCAGATATTCATGAACGACGTNTTCCNGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCTGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACCCCGGGACGCTCAGTAATGTGANGATAGCTGAAAACTGTACGATAAACGGTA
+
,>A$HBE$0*?9@@9-@;'9GG,7%B4GG:>4#F0=@*#(GHC@-=7.!81/6$C;=+'&:50,4E03B4+-8;H8G@0794:,@%:&F;'3F21&)9;>:.A?+6399/"5AF,-:<C,B0=-G*?)16.'=)0+FD#?3:!&9%%,%-@&FG%>>&C9>5&297"DE#E9<&";7G;F-?&7B9H5>H9>.!G%+.%-/+B"6#(C%=#CA:)<&-#4;$5.%3#"%AB:/,.0%..G&EB/D70+(0*A79"7/=;F,1?.FBG'?C(=*A'C7A+,(:E?-8@-'>D2C#>A;C=F#*26$&$@06)
@r5166
CCGGATNAAAGCGGTTCGCGACGAGTANATGCAATTATGGTTNCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGNAACACCAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTNGGCGGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATCTAACGTAACGGAATTATCACTNTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGNCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCGTTCTTCCCATTTCTGATCCTCTTCAAAAGGC
+
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
@r5167
AGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCCCGTCTTATCCGACGGTCGGTCCTGCACGAACNTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGNGGCTCCGTGCCGCCAAAGCCGTCCGNCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCNCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAA
+
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
@r5168
TNTNCGGTCAGGTGCCGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTC
+
&&%(+$()&")&+)*!+!!)+#$$++#(*%*%%#(''%!+''*'(('!*(*+%'
@r5169
CTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGAAGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCNCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGNAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACNCTGTGCCACCACGGACGGGTTACGCGCCACCTCTTCCACCATCAGTTCAAGCCGACGCAGCACCTCCGGCCGGGCATTATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGGACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACC
+
/7,*>4**(.H#7,HE33!4*;!.<29#8><6F"6@'55G6;8$GH=C#H";.G$#3*1;!=77>H5.32B/+5B2..(@5+:'#0<;54=$2&,H-DE:F33:/B3202?"@90<6GD9*,'+3#:5EB!@*E.A25<=&",4F42D:=&0.#G,;(B>+&C0-2B);?;D;/.#A",3/-0,H?.(2#784-*9!40%,):4HE1%45;,F:<-,GGF(0,0*"!:'D+;(&'-%,/<?%$*:<B#9+6-H6F9<=:EC)H$!+@>D;?69+;)'%.0H<*!-*(+)GB$6A+B'@BC+78"(26B"/7-5046/6:85:/6*E-22CA-.-D"%60'..-=>*405>FC7A$47+@";4:@?;514:D)3:-#*?!".D<)&/#"@@!7C<><"#*5?4G:,2+#D$&(9!(6G4"8>#GD/%D%G&864&&H3?D/6%'?"H)98;E#G.506%D$$H$:)5:&B40(09,-G*1(?A2=/B*62H!#249GB!84(B"H9@?#>E@,9=$>-/@B%A)?"/75.&G&'5GD?7:.%GD519*+,(7!>5.+C37@G$:F-)3361!>)=E3D,+2@.)+41>05BG0:/(24""H'DD9:1>,."#:E'%D+"*2+:52$1?A-!-)&@4*$!>1.,5C,%B&F5-!H*.?F)C<H<5:?A*5'+2"G%3.2!B'@H81,">":DC;&C?#C$+&8A(-D.1'99=*+E;!</0;/1B("'*G0%-)>91CE9B.**B.C)+)D+/<?'BDEHAD&02@37&),F.85$:?4(8/!'5)873#5,;B/=%//%E67)*?>9.GF8%0)<C'*?("E539=%A2(2H)+1$#H/"E;,6(F%$.**@2572"<10
@r5170
GCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCANGACGAAAGNNGAACTGATTGCCCNTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACNCCTCTCAGCCGGGAAAATGTGCTGACCNGACATGAAAATGAGGTGG
+
,:C<''5&8G9.1'()*.)4'?).3@,E<6B3H!08E,:)45=4'+*E.A#G?!0?D'E8$#B>*3&%=*(6)&BG(4!2)(0=$-3,CB:31F.%1B47A)H.*23*'/*4E>D@92<,F.!>2*;<@B&?;$B:1E%-?"=8>#A!E:5A-<=-A0206%15C+;7B&D30C.C2$/?;%,5(B"-;6&%/**:;H@2.+5/"/:'22"$?E'A4C8(07.3-?A'8B=-',.7"A7%+&#,=2?/;(F2CE6>!*EED;D0.D(,>G<>?':+F8,>@.
@r5171
ANATGGGTTTANCGNNCNANNCNNGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCT
+
!!(!!!#"'#'!%'"#&#($!)"#(++)%+!*%)#!+(#$*&(%"('+#)(!&*%"#'!$#$#&(#%#!("($'%""$*)')"'"+)&"+(&)%))+($
@r5172
TGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGA
+
91+"::%F@2!)C"C.-?6(D*1?:/#@)"',F-+0BGHC3)(@FB0G:E&"C/B%BE9G1?:B5
@r5173
TGCAGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGGCTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCANGANCGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTT
+
-89#<H*.C-?#,39&/D(?&:>?;7;7+28#62"+.?#H4/FDC>32<3,$"8<AF;(A/@H@'>3@@;<;7)16/#4592D:0(C3HA0B,D"*92,>04#/:*8)6G2=-8'*'"06;30/H4.<5AC6):B$-E!;*&12>27-7"30:H3E+E:3"=*24%FE#H"!!-EC8&<GAE-;EC1?#*<@?#B&4<+2!+5A<G0H;D*!7A(*;$5+?@.$42+C%0A4.3/B)G(08</3-E,%@22%,=;+0B?89BD-?1;E4FF+(1F8*DABE$B#)>/;&9"E(1?&36-;/7('H4,4G2H5F>H61A-@389@@"4#*;-*>>9%/B$0#B&3)5!B#HH=:*3G7
@r5174
CACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACC
+
7BHAFC76@%<&3@@1"DA@A(-E6=5;A.7B0DD*=E<(&7/HF:#:H/G6,;+'""B</2-'CH5)&>,.7)4G39'#/H+%FD%#=+3(.$%50(&(:3@FE1C>;&=G;))?*.#,./1:,(%..D=(-?";<F5*9%."+@&0,$B9#
@r5175
CGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATCAGCCAGCGGGGATTGTTCACCGTAGTGNGTTNGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGNATAACCATGTGNTGATTAACAACGANGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATNAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCNATACTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAATAGCACGGGGGCTGGAAATCGTTTCTGTGGACGCCGCCTTATGTGTGGCGGCAGNTAAAGGTGACCTGNGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGTTCTGGGAAATCGACCTGACAGNGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTNAGCCGGTCACCTGGNAGGGGCGACAGTATCAGCCGTANCCCATTCAGGGGAGCGG
+
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
@r5176
TTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACNAGGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATCCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTNCTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCACCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTAGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTACTTTTTNTGTAATGAGCAGAACGA
+
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
@r5177
TCGGACAGGGTTGAGTTGCCCTGATACCAGGCATAGGCCAGCGCACCGGTCGCCACCGNCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCG
+
*0!@"<.-31?)*4;:!!?B57>5"!5,.8@8)1=EEB.?>01?1>>"1.6#@->?AG5A;?%30=225D7;C%8=!7G*&2"'B$-0:GA':'8&?>0'0@39;D"$-:0-5$"7H*7:=<.%;0=:8036*31646:)BH14C"H;0C&29E0/="9BB9E$>)$*$(&F%3)"->A%)G;E>6+,A;#B!*;/5@;<,4CE2?1$(3&CH<3AF%#A0+5+78.2>D1E!=++5"7D&,"G>G0>75+HFGA<6HC%0'A3'E/*?'%
@r5178
GCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTCCTTACCGTTATCCGTTGTCTGTAAACGGGGAGTTCTGGCTTTCNGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCNGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCNGCCCGGCAATCCGTACCTGATACCAGCNGTCGCTCAGTTTCTGACGAAACGCCNGGAGCTGTGTGCCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTNACACGANGGTCNATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGNTCACTTGTTCAGGAATATGGT
+
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
@r5179
AAGCTCCCNGTNAANAGTAATGAATTATNAAAGGTATANTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAANATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAA
+
*!((&"%("+((+'%#')*'!%(**$"(%!&"((''((+&+')**&+!!)&!"+"!*&)*)""*'#)$(&$(((+**#$'*"!*%"$!&$!'+%&*"%'&'%*"))'#("&%#$"*&'%%&))*%)%&''*#!($$'(&$
@r5180
GGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGNCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCA
+
30?0#.AC>,26E5C8*F*;%/%B;+H;0093$8$?2(D/10!0#'5%<072$=4C,0/'C>,;)!)C!$=&B446!G6(7!-@6?F+<%>:'9?,B!B6>>1".A#>D$&C/G00&).<;G%H:>B7')3:E42&3)G?&C?@-,-G@/3>E6?,ED,>,B:EC8*/
@r5181
GGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTNATTTGTCAAACGCCTGCCCCTGCATCAGGANGTAGCCAGACGGAACGATATCTGNTGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGT
+
=051="D-."4:A*GE+5?H)"9>6.H,,5HFC0F"E0>+7=8,=F+$<>E%7-!BC,1#=1:E&4CA3,0$H9F,&3(%?8G1<*F:2.'H6@!!"'>120G5:51(HA;E;28(>%)&H(99:<28E8&A9&.(6+>>9"6(&2<$>@E=6#B<(<F?F3"?;':<4C"!5!"=EA@AC;:?C/G=14%"<HC5&G?B!DA3C!:,):(#95@C>B&(!8E515<37"+B66:.+<'5'4<?7@@!7<>B355.B+CC+3(<DE##1<4EF*'8CB,.3(;8"&/D64$1,D84B$4>G8(-?F38,6*#B*#:>/,"&"G"'B;H),GG/=B*GD)/#<"F7//$HH5(A):/976"@C&57#3:<<$"1$795A,AH$%8>D+:$)"*G6)0,*3=51F!8,&A;H9C&0%"A)0+61C4%+@A;3<"!H-6?C814F:&!(#(.1-59/9C;0C563"@)5B@9
@r5182
NCCGGATGAAGCCGGGCGTTACAGCATGNATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGNTTTTCCACCATCGCACGNCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGGCGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGNAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCAT
+
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
@r5183
GGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCC
+
=B*:A45,8)D3';H05C&7/+F9F$D0@5/-8#)11.E:5A0%2'00%-%@03/;H9*?19*,D+$73&;F,.E2)/@$,+$"<C33'%)1$6,:C.;#='H!,F4<>H+50$,*-B19&B5B.5E556#./$?>+F2=-4#3"080-</3':BFFE16>>A$82E68C(#.151'B=6?1;2HEB*1&EH?D83=2'485"=#C3'6+G-@:>5'F2"0@.58?9$5-6&3793"775</%:F-@*
@r5184
TGCAATGCGCTTTGGGCAAACCAAGCCAGCTAAAGATCTCGGCGTATATCAANGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACTAATCGAGAGTGCGTTGCTTAACAANATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGNTTCTGACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCNGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTNAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGG
+
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
@r5185
CATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATNATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGNCTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTNGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCNTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGNANATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGAC
+
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
@r5186
GTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGNGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGC
+
<>"DA$%9#6,4H&5.>@=992A$E&8+E0!!@B!:+H=24A<!#.;?17$7<,A<>>$D4A.E87A>>=83B1894(5793<)5D#D,90>'"2*&0%:==F37'!:7H(.=$0D@BBF@?2#B0*<1#D=@D$7AC>!+*?!&7!@9A#CH:1E?'$B9E?HB0:;3FH:2$608$&9#..;/D1<(@'90&A&#".,?!C8<C;%>FE6;33'F566E.:>"-(++D8D5D88!.#
@r5187
NGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCA
+
$1:2%*#(="<EA210H>90,!3.6)<6+0B("28*GD;H$.8A.)4-8D(1%<'5D%C,F5
@r5188
TTTCCGTCNTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGANAAGGTCTGCGTNAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTAGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTC
+
2(.<928@C3?0):&@6$.#@H$0'09'CC.@0>&-2C13+/DF6#5AF-D4E?.""*C=*'@=A.:?)-&BE7B?H,+*:=1@??(8H!2;&'+%?A74C@AF#6*=?)?*):B@D!43HEC;?C:3+(.3"4&<HD3+-?&?38;&,3&CH7A+=F;/HE+0*B*1EF$3H=%"(*4%.$3GE23?40C)$65?##<4./2$;:.(3E@+&1=F3%.,1.G)F7;:7<?+(B:5G-A,BD+.+75$D!@(&?"&%;+.71D"76?A,)H4*H2%?8-:8'A52-#8'26&2=7+':6=04!A>G#99%=;@+CF<"5>=#.63%'G2<%>EG4A"/5)0=(DBE<:8+%<,B3A>'2+))2D4;;FB$!G0(-0@&+>9492.6>EECC'&D7E9,>DA-"!$<-%8DD@;%C(.
@r5189
GGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTGCTCCCCGCAATGCGGGCAGGCAACATGAANACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCCTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGANACGCTTCATGGTGAGCGTGTTATCCCGGTGC
+
8$GG!H,2)B2,<@&G12??(:2H70B#H0=/-C2,EFG!3G%:#2*<7D&+1#,)!8#F)&C97.%@1?"%:)81!(;&@E8D'<B"$=%8<E76;A<46<8-95@A)!+/110,<0=2<7;!F)-"A8H&B)4#&8%;%5@62F*H'6()B",A<<7%=9-)#55!:@1>1.5E@6)3DB!H>2"/(70..."?)CF5465<<'8+;'C9#E#H+"9H.D8.--1CH5.#H,C'AG=(D&%@.(,=2E!=9+A)%!3(89>#/-:3<>'&3G)-=6*.'*D897!D&20D"CG.6C'98>+FH+:712+')!5?3C>4<BD95F-&'%=;G$.-.#!6$3#5.F'%E;!:2/G%6@8>*8<6?>EC,*DHD=C
@r5190
CTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACNGGCAAAGAGGCAATTATTCATTACCTGCGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCA
+
<G/3*86,@'6"#*B4@!&C7>E,@C.A&*+BA89@$8)H7E7<::$=0"%-0&*BG,+G($G8;C"+4:9A)!2*=FD*GB=45FC8*8C*;F6,,32;=*H#!!1DD<%&7-99@:%5/#/4E-9<+4D)-.4C3#8B#6$B(%EAF05(4521'H'*(D$(3;#E:*>74??2,H8
@r5191
TGTACCNNCNAAGAGAGTTATAGCAGTTCTACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAANCNTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCGATGTTTAACANACTTTCATTTGTAATNAACTCAATGNCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTANACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATTCNATAATCTGGTTTTTGTTNTTTTGNATAATAAATGTTACTGTTCTTGCGGTTT
+
*#!!"#!"'$*'"++!!%'*"($)($+*$!+'*&$!#**'!(%(+&)!++$$#!&$')&(&&#)!*+)##)(&+)%#*$#((&"%)*#)+'$%%(*""$%#%!"'*+!*+")&)&$#*'!*$""*'!!'&"()(')'+#$!('&&&")$!"$*&#%'$'!($&#%*'#*($+"#!+%$)&!"#"'$'++#"")+&)%%'#!#!++*)'(+)$*(%%&%*+&""'+*!()')+()+%"+*)%""*"+"&&&#(#**"#++$"*!"#$$&"%&+$'!#"+()(&#&)*+)+(!)*'&"'%(*'+)*&+$""'#$"+*(&$$%'+$"&")!**+&#)%(&!##('*'$!"$)&*"!+&)'#*$**%*&"+!+&+$%$%%*)#*$*+)"*$(("$'!*%##*&+!$%#!(+%'$!+(&'&(##)%"%&#*$!"+(*"'(
@r5192
GCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGTATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAANCCGCACTCAGGCGGCCTNGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTA
+
43*:(*-)A:/9",D18<38$D%>D$!;>D(;!4?1'+D;%6!.9+*F-E#!F8;DB9,??5<GE@'C.!8B6):*3'(:-!'G=%9H-<,/*3F.&AH"-!5,-$5@,7$E!#E=2!>GH)5@;36(-6"4D=:?B%"&C#+./FF6(60/5,CA=EHE5B89A!6H#7HC7@")3!!;5F**2=CH)95C/:?H-:((%>.!+B"5C<)%?A!($D*-:F(A&!--A7D1/B.;/F?0*/5BGA%:<!5"&'A,:#;.=#0BD=&=$"**?+*<B,AA5)H3C/F:>B+0-)CE1>>0A#)"
@r5193
GAACTGGCTGTTGTTACCGGGCAACGAGTTGNTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGNTGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATTATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGNATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATANGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAANTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAANGTCTGTTATGA
+
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
@r5194
NGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGT
+
22+D,H,&"#AG6<;?,'"):GDB(HA2CFCE>+%('!$5#=4B-+%>?EH!C4.26+8A0.C5H6"-(4+%+->2:E(A4!9BB-E
@r5195
TGGTGTGTCNGTGTGAACCAATACTGAAAGAATGGGCATGANCACCGATAACAACCGGATGCTCGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCT
+
"D:9+(@>%*,.9EA#>.9HE3HBG?&;)=FB26BB6:H<>,<5$@4&3D.*8+4:45?+7$+<6C.!EBH"=C*+,?:,/!1=/3',8DEC?$B?,<'3?<.3GH.H8'&$&
@r5196
AGCACCTGTCGTTTCCTTTCATTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGNACGNAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTNCTGTGTTGCGCTGTAATTCTTCTTTTTCTNATGCTGAATCAATGANGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCNATTGCCAGGCTTAAATGAGTTGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAATACGCTACGGCAAATGTCATCGACGTTTNTATCCGGAAACTGCTGTCTGGCTTNTATTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCNCACAGAATATGAAGCCCGCTGCC
+
+"&%!!*#$$(!%"%)($+*'%!!()'+&#)+&)$)!*%"+"!%*$!'$%)&(&#)'*$%&))+(%'&%'%)*(*!!!+(+$+&'"!#&)%'('#'+#(#"!+#%&#%"%'%!#%"+%'"(!%$"*+&$*&"+)#(()%)&(#!%%%!*)(+*$'(+##(*('&*"*!)"&+%&"$#&)'#%*!%#"&')!*#*(*(&&+"!)*!&''(+)+!$+)*+*&+"**()&$%*#$+*!$('+%"$(+&%'($$$%&+)&%&"")$)$'#'+$#+"#&#*$'#(+#(+#&!#+'"!)+%%%+++&)#(+#'&+'!+#!"$$#*)+*%*&&+#"""$)%*)''"+%(#!!%"#'$+#+'#*#)(+"%#&**!&%))&(!)!$!!($"!*)'$+)(*&*!!*$+"$$)(####*#$""('"*'"+$*!)#$'!()")(*#%!%!%'%$*'(****+$$%&")$&*%"$*%$(+*""*"(&)(#)(+&&+&#+$)+&#'&)+((*"&!)(+$+$"'(+'#"$&#"(&(!&%!%!)+*&'%!%(+"!#(**++'&"#+(*'"*&%'(+
@r5197
CTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCNGAATTATTTCGCTTGAATTTGAATCNATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAAAGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTNTTACAAATGAAAGTATGTTAAACATTGGTATAAAAAANTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTNCGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCC
+
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
@r5198
TGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTNACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCNTAATTCCGCATC
+
9%97(5H#9=.E39C-A#3?63G*$@8@D-*F7*:%+*D%,9)/-E7<<6H$H6>))'5.9(4?/7&<2-(F,0C'1C=HF!/F,"9E#3"8#;<9G'8"8':)E?=.(/G"/%+47F607/*%(@,=(98575!(F%E810>$..9:,*&6F>4&=.C&;35..=7HB"!;E5&&!$=%:D,727-0!C%9;D."HF7'2*=C28>11"-%56
@r5199
NATCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCNGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCNGCAACACCCGATACTTCTTCCAGGNTTCCAGCAACGAGGTNTCTTCCTTCGTTGCAAGTTCCAGATCTGCAGCATCCTGAAGCGGNGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTNCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCTGGTAACGGACCGAGTTCAGAAATAANTAACGCGTCGCCGGAAGCCGCGTCATAGACGGTTTTACCCCGATGGTCTNCAACGAGATGCCACGATGCNTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATANGCGTCACCTTCACCAATAAATTCATTANTTCCGGCCAGCAGATTATAAATTTATATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTGCGCGTTACCCGCAGCGTTAACGGTGATGGTGTNTCCGTGTGAACCAATAC
+
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
@r5200
NTCAANCNNNTNACTNTNTGNGNTTCGGAGTNGAGNGAAAATTCCCCTAATTCGATGAAGATTTTTGCTCAATTGTTATCAGTTATGCGCCGACC
+
'((!'&%$"$'&$'$&)%%*"%"()''(')"")"$"&+'$"&(!(((%''*")(!&%+"%%")!(##+#*&+%(!!*#"+("+%$&+&#($"%++
@r5201
ANTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTNACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTNTGTGCTNGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAAACGGNGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCNGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGANGGCGTTTACGGCTTG
+
*"*)+%#!*'(*!#")++%$)"(!($'&!%!"#&)))(%)(#"(&""))'&(#!(+"+#)*(#'"'#(*&(($$#%%"'*$$')(%#$%*('+'(#%'"#""%()+()%!'")%"$*)&(!&)#++&&!!'**"'$*'!&))#**)!!+(!#'#'+#''(&&'!)$+(&&+''&+#+"&'#&*((("#)%*&%&*(*#("*&'#+*$('")"$"*$+*'%'&$))"+&%"#(*'!(&'"#$')#%+!+#)+#%**%*(*(!!**+#"(#'''+$"'&)&($%%!%")!!!&#'#+!%(++%*('&*%!*#%$)%"*+#!%$$#(*#%(''%&'$)(!$!%$'&"&(++"+%(+"''%&&)+**)+)+#*"+"+&$())#&*")"&"($%!$$+(!#"&%!+*$+'#)'+"+'$'#+%$$$#(#$%"!'$)$!#$$*%"))%!)'&&((&'%&'#"($
@r5202
CATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTA
+
$9A)B6&E3.0-8#)!).DG?>%2-+*!C$$8F7%!.0.)AE3F&0<?914)?&,6".E?HD5'10*%F%?!5&/4#8C/1&FE-@8',1&-GA!+#!+6*G?'"&7&>8'%#)%8F()"1$>E(=5!.+C
@r5203
AATCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCNGTCCGGTGTCAGGGAAAAGGCCTGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATANCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCT
+
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
@r5204
CAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTNAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATA
+
>?<&2>-";$.9-4*4C&&B%C0$4/"0-?</B.A4A,/5$3./08(9"!(F@609@;6-/910%C3?>89%46&F+DE,D,057GE-!;6$D1(
@r5205
NNCGCCTNTGCNAANCTNTACATTNNCATCTCGCNTTGNTTTTCCAACGTT
+
&!!#**$"#$%#(""$'!''"!$*###(#"&&()!*"'&#%*(#'"&%'#%
@r5206
TAATAGCGATGCGTAATGATGTCGATAGTTACTAANGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAA
+
?8,)/+%6A<>ED,E!'@/A;H0!9G,%CG#'>+6?!7!/?:>!*!1>CF0><E<9*'1B@"(&@<:"%BC6)0@8*=-D8=60+A!3EB/3-F#5187;6((H&>D$-/.G1E139;D8F27!/DA47@"
@r5207
GAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCAACCNTTGCCTGCTTAAGCAGAATTTCTGTCANCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGC
+
F4?.,:->#$EB19H+C!GE:F6C@G9=@A>9D80%.HA=50&C>=4D5A.G1"9!2*.*7#-F5/HG7@GE(;=?5=#H4EC*;@7H5B,%E17,*%*?471=(@$,3/:G4"G76';1#1-GF*29#/%$A(7*7='F.$24%234)8.2".:A%&2!3-"%$C9!9=#
@r5208
GCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGNCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGTGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAG
+
;4%$45?A05510=25,*:-':9F#0;#/,.4B%5*!34&36#0AF2B7(..D#(#1@.%108H"5:F*2D:(@>#C?"5.?280F/6?**G+1-)2G4/A'$>26BH4E)6?8C(=>8B20'/A8A73/%)A&,.4.@&=%5/G65+$>H/'=C/CH>;F/#0B8>+;4?5$%D17&-C?8/$F:!,)?$#?!D(,"+&"-910-5'D3AB?B0<$B5<1'%8$$3G#>F!3+!%C*:"")G+D2@DC,)E-EF$"%;4:3*320:<AC.B84.B8#C*)6!",0H>FDD9(46,0(8CCA-)(51$%9?',F4(#GE5H9@?9<FE!6"(/+:0C(2%8/,6"=G+369<<G@8'B7.;!#-::8)$;010-3-0+A%;E9)1+"9#*G6#130+/+-<4,-*
@r5209
ANGNANCCNCGCCAGATGATAAGCAACCCGGAACAGTGTGTAACAGTCCGTCACACCNTGCTCAATGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGG
+
#%#&"!)(+%(+(("*#''%$!'!"#%$$*))+(#&'()"&%%%+#'+)*#'))("#"!$!$&$&"*(#&)+*++"*&)#+!*"%#)"!#*%!###)+&'!%!(%(#%)%*###+*#&
@r5210
CCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTNCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAANATGCTNACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATCGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCANTCCCGGCAAGGTTAGGAACAAAATCCTGCTGCTTTAATGCTGCGGTAAACNCACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTT
+
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
@r5211
CTCGAACGACGAAGTAAAGAANGCGAAAAAGCGGAAAAAGCAGCAG
+
(2-B.),?/:),G%-'):'6+%H<>?+7+&F)#3+:1,7;+0'6:#
@r5212
ACTGTCAGGTGGCTCAATCTCTTCACCGGAAGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCNGATATAACG
+
4CGC/*%)5+-H-$!#'+=(;G?86234=**8F6#6F+F3AHHE2BD=FF&5(-"H5/1=;,&)#-@06G/6H(+E#*A5.%5!16'G8/
@r5213
NAGAGTCCTCAAAAAACGCGGCGNCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGGATGCTGCAGCGTCACNACAATCAGCNGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAG
+
)ECEF7)D.89<'4((>77<3,9,-341*)D8*80'!>B10)%G+F'";BD"A*+#!.*1%/4=<:GA/!14G-H2$>:1"/.%5.16==*F!.E?F1)1A,0","'304!(*%-03D:E%?,%9H5F<=402B4"C5C))//!B92=6#6?(DCG8).1!F
@r5214
TTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGA
+
)>'7=$?$H=0'/8"8;D"@(6A!);E1*+?/9<$"4,4<;)E'*(,5)$C1.6BD43G/<72G;989)!.##5AH'335@6
@r5215
ACCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTNCTGTTTCAGGANTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCNGGGAACAGAGCGGCAATAAGTCGTCATCC
+
C=%D1B&5,+;3;1/?-=="#*7*G20C"#>+:F*9F4*5(0288!?>&8/?1)F03E747"7(1D*1,0<C!CA%&%(03@+"&A"(-C)%!"+A,7=+*-3',3C&3<$.@".5=HC"2AG*19876/-8C-5&%2G$<.//HH846/G+$8;$GGC;":+H:(FH'2C<66'!A/"&B<,$F?1+'2,9@BG*A:&-B
@r5216
CTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTCGAACTCACACACANCACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATTCAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAATTTTTCCTCTGTCATTNCGTCATGGTCGATTTCAATTTCTATTGAGGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATNTCCTCACAGATAAAAAATCGCNCTCACACTGGAGGGCAAAGAAGAT
+
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
@r5217
AGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCANGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGNAAGATTTTTTTAACTANAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCNAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATNGTTATCT
+
,#A,;H!2'@(2.$DCG5#*7C,5D!C;%/E?C%:D:411G7>A-$F+D6#>&F*@.7",-#(23H5D3'(=18((C6A')2))3%79?2*$B2?$422&?6064$G<F@'F?%@F,!H+#%=E>)7.8B>/8'3"32(0#6.A18/@;.C@-'=E&H74=A<#)G'$)H.#F!78$8.+=1A/+6:EG/1$,*!-=-4CE6DC$3#F-;3>&2>=)/-<45/*'+:!<34<-C,<::D09?"7,6*!E.E/<$?%7D)0<4:?5D$9&70C-,F'%:*"):*$0;"#F-&8HDD#+<+F5/8%(56&AD/7/
@r5218
CGGCTGAAATATACCGAAGAGGCGCAGAAGGCNTACGAACGGCTGCAGACGCCGCTGGNGAAATATACCGCCCGTCAGGANGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGNCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGAGAT
+
*)'+"'%&"%))()"''!&%%&&&"++"'#$+)$+&'!&&%)+'"%%(%$&%+&+&#!$$%%''*)))+)&$#%(#!#$$&&(%)&"!&$+"+%*%$"*$+#"+$$!%*+)%$%'(#++&(&&#!"#("!'$%!'%#$#!(%"*)"%&$%+%##(*)%*$!'"""*%&'$&("("!'!&(*"#*%#*#!')%"$))($!####(++($##)'!$##
@r5219
CTNCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAANTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCTCTGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTNCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTANACTTATAAACCTTCATGGAATATTTGTATGCCGNCTCTATATCTATA
+
'##"##(*+#&"%'(('&'+)'&""*'&'&!"!#$$+*)$("%#)($!*"*"*($''&)))!$$)'$!%%%(*+"'(+($$*('+%('!###("#'!%%("(+$+&()*)""(*#)"+'%%("(#+&)'#)!%%&&&%##*(%$$'$)*$%(("'&*)$#!$(()'+#+"&**#"))"'"($!$$)&'!#'"+(+')(*&&+**%+"")!!"$!("!("+)+%'$%)#+($*("!'*#((%%((#"(+#!!*&"+"&((+(%#%#*#&(""''&'"$%$&&)(+"')'&("""#(+##%""&&*&#!!+!$'&*&
@r5220
GTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGNTAAATANGCAATACCCTNTGTGCTGGTTCNTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCCCGGNCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAAT
+
-G&GFDE!:F7,#;!2'2D$E4A?*/+(41-GG2H(#4C$;<B-8FE*4#-4'E:+#5-"%B6C+3=A!1'=:E/2'?G4@94B&;BH=+!8CF,/-1?49@5*:3?<BE<025*@@21?(A80,$6*G>6#5>247H036,?95#-+'<,#9=>@'3,D'?0E+H1;1'#AH#7$(=$:C4,@31>6FA08-6.B?++,%H//*E';&5"6(5/*)95-/H9@""'*:;#*=DA=H&?.&0#+(#D5E&;"A"%&381@D;-8AB6>=AE$2:;(<&.C)3+%F-A5+@:47/=<E,DC+CF-62G4#=@8+$H+!@:A;/414G$H7&59;#'";.6CD"?H&-?14B-@*9&5+CC%3.3"'*069;"=4&*>$FA)2G'4*"9(.@DA:E6-1$%?0/?*.(;,(.*7FB3E)'.%G6=F-)D0!/&+$.DE-,(@$2F;5==.BB68:G#/C@@9,9@G8
@r5221
CACACCCTGTTTCTCCGCAACACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCNCTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCC
+
)9>=4+A.44E53:;%"-%F6@GD!F:+H6H29A-8A?;.G43'A/FA#E%(38>(>C/D?C+A.B47:3A56:"C?8#FF#/>&-.@DHC9/68#0)<7A3(539&;D2=2'0+B(0+?+D+EE0($@1?GG3EHEF!13"$=?62C2")%<B%>5"=+D':"%+&;,3DAG!;&9H))?@4(<G/7//!3-H(4A!;/9)2B="$H5,9#E:+D+G;4&,;,?
@r5222
NNCANCCATTGCATCGCTTGAATTGTCCACACCATTGATTNTTATCAATAG
+
$$'*"+'&'&!)++#$)!'"!)+!)&&*+'(()))&))!+*"++#('"*"$
@r5223
AGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCG
+
+&-.8&3!D5.%5<E-7;**%E7*!+&6/@?43(B72A7D5@4G;==$<DB1/3,(C('3/8-0"9B+5)HD#:1<#*G0CA942E,2+E412#0EC"),)BF'@H&<7D@/:+"4)@:@6"A,,:&@&"
@r5224
TTACTGGATTCAACTAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGANACCGACTTACCATGTATCTCGTGCGGATCGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCACAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTNGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTGCTCAGTAAAAACCNTTCCAGACATGCTCGTTTAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAANTGCACGCCATCGTCAACGACGNTCTCATGGTTCN
+
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
@r5225
AAAGATTTCCAATAANCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAACACAGTGCAGTGTNTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTGGTATTGCCCATTTATCGACATATTTCCCATNTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATATTCGTAGTC
+
!08"5-BE/&C?1B,?DB7D,#A/;4F85-'E/8=3<"5E0:E74"?!2?'.97-4=$39D*7C=*-?2!-$5='4:B(,#"=?>,415;(.&4#':,-&6>*GC,?%D$*8!/C7?8F?>20$)'9()+$5<;9E'@!)!<+8BC<4!?F##9(-6'<&H/&'/H)8?21&;$%?"9H#)!>;?@-C,+3F"F+#*D,7>!<B9+-&%'DGE$$48(H&3+FEC<26?=6F$5-7HF;E"@7&<'H<+$:&7*80;3F=%:D2$/E'.(=7?;6<=-0C&F92HA"3#>3)5%"!AC%$=+%D&$H5*)$;1B?&+3#85=*<GH"&C<
@r5226
ACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCNGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACNTCGTCAACGGAAACAGTTATGCCGATCCGGAGCAGGAGGTGATCAGCCCCTGGCGCATTGAGCAGTGCAGNGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTNGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCNGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATNGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCNNGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGNACGATTCNTAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCNGGGAAGCTTATCATCTGGCGGGGATTGAGATGCCGGANTTTCATCGTGCGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGNTAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGNCGATGTNCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGATAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCANGGCGCGCATCTGCCTTTACGGGGATTTACAACG
+
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
@r5227
ACGGTTAGCCAGGCTCGCCGGGAAAGTTGGCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGNTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGGGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGNTTGGCAGGTCGAGTTTTGGTTTGCTGGCTTTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCA
+
BCB*/CD'-&.;@;5!(DB-/*CB+;?1E!7C8>?1D#6AC&23AH"/!B"+%<C(5;-6G(>:>4@G*"H-,(D)8$)D59&&=<*FD#$7":@:(!F8'"'6?8&;<#<6>E*#H$G>%G",'5,"?)*H3H)9DE.2/H)*(049A*/E<-6-.;,3C5<@(4D&CFA'/+E8C-2,%4%7C"+H#7(1%3.48E;1!,EG2ACD3;F83=$7<=",C9&:,@G$@1BE7!51HH5".@B@+9>%GD(,,#80/3B>)2BBG$BF2(-)=9FF29$<9)F.8#)?".+<GAG=0@#9<%.(:*"
@r5228
AAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTCAAAAGCGATGATAATGAACAGAGA
+
;0#6.E2#!%!"HH!4=E7>.<=)0E52,)(*E7>(B7%=7H&:0#/*86'(47!A8FA<CH<>,),%:8/'8!)!;*."4$82=E?&940#<+.,8%4:B*A3D?;8"89G>!"(<?==*3C20#.9G3:@7D=&E$;./E!0,,C?F4%:!'744%2+@+=1+1B>87@G3):#H$$H;$:&4H'.2,6C"1/<54:H&+>-FA%)/!")3&:!8$96-G4"G$-(-76('85BG?.;,/
@r5229
GTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATACAATGTTTTTGACGGTGTTTTCNGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAA
+
F'F9F/3-;5@14-;BH:"2'086G.%,,>D&+(=3?A9E/:/@+7'<G1+93?6=A5=#'+D/?H<4!6>)B5"+=+2>G'!<+-@:!!/+@1'#GB@!<4,722F")8@!'>8'+=H*90'@D?<'&F$3B%9022H%.,E87$GA"CH=%0$>=0D$(5B5(G%.90+AF""$!0F+49&9&#?29C"*-<+"FC$F858-A3)++6/840.H?DC5>3,+)&H0');%%#9<!/:"E*+3<,:;/("%+9==(/+B3@<*<;DG@;)F%9D<B>E'"4/HA*'40"9&36>+6C8@A3&?/&6-@>BD.',<,B"@/95)((E&@!+&3@8<!1;=':&(='/FD'A:9'.%7:A+E>!/+>::@!0;"3H,4B
@r5230
GTCCCCCNCTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGNTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGT
+
0E$H/23A:!024$,A#1%-;!H>G5G9#>$3B+8@@1286@&1D*-8B8B7=H4+<C+@<5?=6"0H3B$?$'A-&D>.-3:C&/)!89'&G/B!:%G<C5+:*2)"AC%5/(7$3#DA@A9B"!E-@=:0'/2780B%/5"@!9(725A?;@+4,#"!%6GE@A%,+;#8:A)9@)4@6"
@r5231
TAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCNCTATGAGCTGAAAAAGAAACACC
+
&%>;6+=#-;5+5/-$EH7.1=F-:$CD7#..':(6::2*&E+:"5=4332A6C"B'9GD:0'2A#E1,9'H4#&G2;#'HGF63GD$+/
@r5232
GTGACCGATGACCATCCTTTTGATCGCCAGATAGNGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGNGTACTNTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATGTATGATGGCGCGGCGAACGAGGCGGTACANGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATGAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACTATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGNCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGNTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTNAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGNNGATACGTNTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTATTACAAATCAGNAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGA
+
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
@r5233
TGGTGAAATTGCCGCGTATTACNCCGCAGCNCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGTCGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATT
+
:,G/7*<G5E4,&306$-&$>".?$E9>5"%0&,!$3@1;A,=!5F%*?5.$909GA>>4**B3F<5)G>#@2+1'B9.69=75$;D25%*@/:+'6#+')FC/$A55G=1(B+93G/?ACF&+*G9-4AE,7<H8BB05F7*+645E2)6$-!454(0,?BHF%B.3C%2ED4B6;-DH674>&*%6HE6',324E
@r5234
NTTGGCTTTATGANGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCNTGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTG
+
($2C-/11))..1/&59/+F/27/(DG+9>4!>0)A/6/-#91!(<"@)D7;G9/-5"E=A!C@!3;(D8/50-31@B/*"?<51ED?H02)GH)$2(.=>:9'7&G;67818!19!HE1*C%,8AD+!5:D-+14D'9>'AD$'8&+:4(H2=0(F'.CHC>'B9E36$&#?*&0)(8-FGF*E3"B#587#*D'%<6727@G;"/7"5#&D=:+G4,CD<=(6!&D8),186F70?*99'5/2@1#2-=6B>8=6E-GH?.;81;87'(5-,F60.B37@"0;'6'269A*5FF1/7,'F>!07A,,E"/4=3E6*),2>.GE%0:,4*:-?#2*F@4?H8*#5%"7D/5G*-*$),#"$&9@&&@B"0C>>3%1-A626G6<30F7-H549%2B0BE;GHB&ED7;##(45&#'B9*9H*/&#,*A9E"@DA52=$13H1"%8.+B5:)
@r5235
GAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAATAAGGTTGATTTGGTCGGNAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGNACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGGATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGAGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGANCTCATTAANAACACGCTGCAATCCCTCCCCATCTTTGCAGGNAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGACTATGCAGTTACCGAGATNTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATNTCTGATTCCAGGCTTNGGCTTTAGCCACTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTANTTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAANGTAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGNCATA
+
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
@r5236
ACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCNTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGNATAGTGCCGTTGCTGTCTTTGCCGCACTTNCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCGGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCTTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGANACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCCGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATANTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGT
+
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
@r5237
GGAAACCNGTTTCTTGTTGTTCNCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGANGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTNAATTTCGCGACGTCTTCACAGCGATGCCAGAGTCTATAGTGTCAGATGATGACC
+
D=!&=5()E?A>2?43"#@?&#/+C<(1$G?"9<;D*4))9>+#-(-%BB0$F-GH4.#-07DC#+:(2+4@G40>7*$C=*40!=<?D3:>E4DEAH?G4=;.!.G#=C#7D%>3&8..6FH-+#(?4;C+CD.@7"!+:CG'!8.>5,)&923&)$*,+%A3F1;B/"3G<D:#%!5*#<"E;2('A/E&(E7=!.'$(HD&60-&1&,#/$EC1)-6F97BE7CF3G.1;A)2#%19,D-6"(2'7+&3>$A&;='>*<20#$3HH+C7"@D7@C07C9<<702(/###@H@BDA-:9:%(>=G#A@FC'35@9
@r5238
TATATAACGAGCGTGTNTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTNATCAAACGGTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTNGTCGGAGGGAACTGATAACGGACGTCAGAAAACCGGAAANCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCT
+
)'$*+!)%))()))"&*$&"'!)*#+##+'"%)'*'$%+)'"*(#$%+!*$)%"!#!$$&!'""+$#*)'#&'('"+$)!%)&"!$#+'%$!*'+$+&($('+%!*&%$&#&'"$%!()$*$"$#$&('$%(*++%$)+*%(*$&%$"!$*$%"$"*$+"#*%!#"$&%$')&&($'$!&#()"#!$+"$&*#'(()))++&$%#'*#$&%%"*+'")#$#)'+#(&#+&&#"&#'!""$"!*'%)#'&*!($"%
@r5239
TCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACANCGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACANCAGGCCACTCAATATGAGGTGCAGTTGATGTATCAGCACGGTTCAGCAANACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTNTGTTTCTTCCGCCTCCTGGATCC
+
8CEEA%)9D%H+2*,DD(B4>D'A'C7+.91)+>01%E2&*4#6$%&:29!?*7"2,)H&:69-#H?$@?7D-/0)*8%-2?G:6!(,F(4;&AC6"7A1;1D>B,));0!E+"?D/FH*B%%2A+>%"B55:7*+CB$1HB%%$BD%06>@,39;8/F=$=@A/"@*+&=>A=?DF-%&7+E();;?-&=%C((+"),D7"&4%0#'%=-E&'DF533??D2D6>/!H0$9FF(<9+"8%C1-22C>-8G84)@>7@$2=61(C+1<346:!#F/:3()7#@%5<+#!/&@0G01:B0:G??A))#4D#>;.@A)"D($B:F'H)8=?=',1:7AA-*0<2%-;<#0G#H,3>C'A"%:*C19-@,(,,!69&18E#8:**(.44,=68%5/-<D.C3F=&>3#<H!GC@>+A2-B)4?$:%'D0%7B,F+/-2G>-#H5>,>#>02?<$"0H:43*2.'8F8D517@2C+9(7$3$8+2%361E6/--
@r5240
TATGGGCGCTTGCCAACGACATGAACTGCAGTGCANGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGNCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCANTGTACAGCGG
+
5#>7F."7,GG@%D?,+,%6C%%A0$!=55GE?/+?A??"A?ED+=D?-:'A?8H%DF=;27<%*:C6:";2G;C0EC1$+%@A63"3/2HBE(*-8020832<DA0-/C>A21,138C1H>$""!3*!2=3C9<,?(+:.=?;A4"9/<'*:(>/,+AD(8@(?=1$!6),/4D3030C#.7=B2C("<+#,9-D>"H<!-7;G*C3H66;DF2%+F1C6*.+7/(!4*"05)8-(@)>EC$B<//4*#FD,8$@,'%&G:=<)A0)"H:@%'3(<4>(;C.G4;"A'1%@,A</2?8%*@E)$:$>F*$A+100'!&+!..C@AA!?"?7<?C?277,?B0
@r5241
CGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTT
+
/;-CH172*:?5/%2%C724*GD$:,(7";B/=;@567"<?464D131&>76BA7!+9<:&>@79&%@'*F7A'-3FH@ED6>.-<GB;#.9$'6*8B!F,?8>-=$(7H.C0/4*!D4"+76C(D=E6H8?2:-</A)</A<.B-@&04:"D+?('CA=$
@r5242
GTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATCGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGAAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGN
+
/C0E9FF"EF7=18E?1=',F.&"/0<"#1;0"C*7"?&-4?-1>6A2-C0%,+$(A6=%20H%"532!5='"='G*DG)4#4*3:0"3+58'48$'<:=4ABA4>G9G:7--)4+C6B)1179??<0&79@F97#B)E:?,,H(/3'-C-0*14=7";2CE>7$%HF=)9!9(G/"(D%-!0&#C8<#"EBDE7,EE$&4>?8?.#.;0$;+:@#<&=82@?0F'!C+C)A%@0C&EB??->+,8C+91*,626;4$9=<E/$C7>=;&;B$1;:6H"%'E0+#-9&:>5)CB'E78/)>A?:*+7"55#33*FE#"83HB</.D3CD=$<9,)?2'((<A2D8HF&=2953,6/A0=$"-&@"$/1'+,?)#<;4?G.7';:;EG-=*!)2$(=?F1/91%$D@36%H4B@""1F:?9,$"
@r5243
TTACTGACATNCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAG
+
$&<443#-0*0!#7(.,09;7#"?)&FCB)4,D1(/52CF9F3)*H#@3@3FA*GAA*GF;;+FCC
@r5244
CAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAG
+
4+:@.)GF-%3::H%(,D<65??1D6(!F77=/>B;+?&@?9+A8A8?*0.>+G5FD!3D6',BA,?!#8%"1"(>-(2(@"4>FCA'982.6;DE%C0$G.$3%@C#*'5.D)6HFE#4&%C8%7?E/=G(C7>*8>5+C'=@>.0?G<!*B3?9@:F3='+*9;?H!4+#H6C1-DG*=$<8E6<>=0,376E?*)F9=55(*6+326<&"8@G3=5$;&905,4F%709<C,@>)7B@HD""@F"<@%=%(3G2#.6(%5/6:2(?+3A*C=-@#1A77=2"/@?.#4B)<HA&3G17(:D)*=;F.<=<6DA=@+E.0**H=:.;(,D5'4/7.A3F(577;1,+&:G37;E75,=0C/&#,&=)9)5&!>1%E=;)H5=1&B.5),-D%F0%9*C.-6<7-A:5H'!B7+)(2'<"E,<D.;/+2&+6.BG
@r5245
ATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGA
+
H<.,>*2/C#--?C+"+$=::%@G5G)27#1!9+2.12F;(*.1'."G=9H@3&H,C/6C)*,%7('E%/)BBC0F/9/C"=CFHE=!B45%F5#A.*,!'81BG=2GD-?!,;-/3:'
@r5246
TCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGNAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGCGCAGGCCGTTGAAAACCTAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCACCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCNTCACAGGTTGCCCGTGAGNCAAAGGTACGCCNGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAATATGCCACACATGAGGAANACCGATTCTCTC
+
5"6'=76)$/C4;(@<)49%7(3HF(&9'>-1<C50+F),62$'<"/DH58>9BG90?.$#(:*FD?07!-&5-*$=:&)$-$%8B2'0<8"@9,3H>:(%@2$"B)76(CE:@&B521B7E*%"67&B+(&<52@9:3$:>3.-8%5H%D%F5>."<G+!=;#D"0*G"FF6%<=@C'8#.9D::A/#D4;>@:H8%9E4!'4GA:+):0))25B3-C?>!C2.:A&+D2>;%=6&)7F*?()0D.H:")F';70:?/+-$##8==<&<1>,?"(.26-,,4=AC:H7%$/%5*-"F?9'(A2'$5AG(&6H8>>$1+/99<?$+FG.$H/@5="!4BDD%!,+?G6B4*C8)-28-ACA>2;6$/788>"#6'"#8#+0<$<10+DC8E#&(3H!=(2C49B>1*7!@.-:.*EF"0#6;A$$C@G20C8"G!=
@r5247
TGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACCTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAAC
+
@9'.?87)4D#:GFF$#9;0%29-7!=3,<19-.#BB;8/941%D)">@(6,(6,94CB(?B<0/10"=21>>&6%6CG1=>*2D)A@H>!<,1@0,B-B>EE%GH*1G?8@)0/AE$&1@:E44%):)(,!G373:"A4>+EA.1%C9+!?E7.C$B>A+(33)FDC.C7GBH7.0>#->(=)A+F=40'&9*-?!&5A=5*!?41,$;'D%"@A-.%0,F0(
@r5248
GNTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGG
+
(%0C-##A,0=>/B-&=?%(=:5,!A4'!=%229=$1%"B43-*-:H/EH?<,8D!
@r5249
CCACGGCGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGNGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGNCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTC
+
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
@r5250
NATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGA
+
*53-$?+28('(#92)$4)#H%9#?+'1;2*644-%4B38<H@!#
@r5251
TCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATNCAGCGCAGTGTCACTGCNCGCCTGTGCACNCTGTGGTGCTCCGNCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGNCTGTTCTTCGCGTCCGTNAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGGGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTNGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGGCCGGCATCAATGGCCNCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTACATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAG
+
+&(!+''#'%$&+&!)'+**"+(+++((%(&(#*%"(%&"#$)&%!"'+"+!'&+'$!$&%&*'"'+!%"+"#"$"%'#"!$"!#+'+%#(+)'!*$$$#**#"+*%!(#+'%$))&&""(&%'*%+)!#("+'+"+$)'")$$"''""!(&!!)+*&'%&'+!)%*)(+')#(+&#"$("%#'$!#*&*"')(+!#%#%$%)')!%)!+("%(!#+#'(*!+*))+%"*+)%+"'+$"'!+$")!+'*$(#%'*$!()##$)"'$#!+&$)'"%!+"'"*+$!$'%*)&!!'&&'*+&#('(&)#+%&&!)$%#"*(*&(%'#")$)!'!$%#'"*'$)'$)($*#+%%+("#$+"*)#&$%%#$)&!)+$&#)$$$$)!))#"!$!*+#+)#$'"&"'!*&(+&'%!$")$$*"(+!&%#!#&(#))%%''&(#("+)*(*()$!&)'%"''"%)*&%&)$))!+#&(#"!)'+#$&*$"#"'%'+#$%+!!(!!)+#"$$%$!(+'!*"!**"))+&"*!%*(*$*("&%")*$(#$!!)*$'%+#%')!*()"!)!)(+%)%!%"#")(%%!'&'&#+')'()**'+"&'!&*"''++'++&#*!*""*%"*)'#+%(+"!*%+
@r5252
CCGGCGGTAAAGAATGANCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCNGTA
+
E*#7$%<?4?5$:,=&D2G0&>:A;4!';8E<0##08E'/DGB8E+350>>AE@@'F;GF+<@(B<C%50B<=DF@:D&=0E+34GD%/&@3'&&C/&CH&93E&/G5>A$''"83C+?>7#3@%C&
@r5253
AACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGNTATCACCACGATCAATC
+
FH+F?8<62H.3>6C/8#>+'-/:,-B:$H;;#+::2*,?C:.;F=700CDA1B:*7!$5H@7.),6D%A;B%/
@r5254
NTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGNGGCGGCCTCNGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTNCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGGGGCACTTTTTTCCGCTTCAGTGGCCTTTGNTGATGCCGCTNCTGCNCCGGAGGACGCATNCTGAGCTNACGATGCAGCCTGTCCGGCGGTCGNGCTGNCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACNTGAGCAGC
+
$#+$)%!#%(+&)*#)'"&)'$+#+"*"%)$+%+&+&%!(+)*!&#'&###&'+(')%**"%('((""*%&))'!)"+!'"&*$*'*$(#'$#+$($!$$)$'+%'+'$&)$#+#'$)+(%%")*(++%!&"%)%"('($'!#*!+#$+#"'$(!(%&"%'!'(!&#&+!*&&#'"#%'(#))**(*##*)!&&!!"!+#%$+)')##*#+*$%'(&)%"*)'"#!$!$!%&"#%"(!%%+$%*!!#%#$%*#"&&"#!)&*%)"%&&*('**$!"!'"*($&%)%#"$"#*&("(%!'**!$%*(*'$("*$"*$**"!+$$%')+))%*&'$&"$!)!'*%%+#+('#*)($*%!#"***#!$***%%!'!'")#&&$*#$+!$**"$"*$#"+'#"("')$++&*&*"(#('")")*%!(!*#$%*+*&$''!*!#'!%$*("
@r5255
AATACGACNGTTACCCACCACAAGCACGCTGCCGCCTTNCAGGGATNAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAANCCNCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATG
+
331C=8%D&68<,%E4D.E'3?)CH1&(:G4=-F)!13"H?*.:E8C,8@A4E&BC<./-*!9*=$-1>""-6>G9/.@%.:+7@/B26A*/69B&<A-2A+A$++:<C,<-.8/%<H0+B4'F2'>?.H(*4".75**$8DFG;F3=D5(F'G72&.*&C#'-"##9*)83<?@C/#CAB=;732DD))BE)561'>1
@r5256
TGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCA
+
)9<3D7D'+D4H+"&(3@.3&<H?,8<5*'E'!:=2!178E)!*?2E"28'6=F:F;;2<*B.;,@$H+-$,<#8"#G+G%">B+G9
@r5257
AAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTNCGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTAACCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTANCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGACGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATNTCTTTTTCCGTCACCCAGCAACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGCGGTGGTTTCCANCAGTGCCTGTACACCGAAGGTAAAGCGCA
+
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
@r5258
CGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGT
+
4!;7BF!$;+,?EF:@3?#&,+,7(D'CC4@0(9>86+:E#<E5,F4.:
@r5259
TGCCAGAATTGTCGGATTTCCACTTTTCATTNAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGANCATTCATGCTTTTATCGGGCGGAATGGGTGTGGNAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTNGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGNAATGAACCACAGATTCAAGTGGACGAAGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAA
+
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
@r5260
GAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTT
+
4>@@40'EE=8BDA%8*;,6>@6&-%69@H($G$=A&*">%7)3A@E;(:E;!3E//91=E&(43$19"-(+6=7*/-:%<='"&"#8'$$#%FA>%EGC;@C%.(A5(%$>9;B?>8
@r5261
GCTGACTGCGTATCCAGCTCACTCTCCATGGTGGCGGCATACATCGCCT
+
F=.BG243@2:A#'%2=/(?2$3:?B0!,H$+.)6D"7E??#@87$@9+
@r5262
CACCAGTATGGTGGNCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGNGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGNNAAAGTTAAAGACCNGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAAATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCANGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGTTCA
+
2#!)2H)#10-10%D8B15476"#8#(<E45<E.%,%,&G8:@$"'5+H?0DC@5$1!%'18-%;!*G*(+<FE3'G'!:/95!)8"3&*<@1$<(A4?#:;=!D(C#005H?$F)?3#6+'9<;=0637)&+E.81BE&'?"<D%F"&/54D8".HFEDB5:%'3.F@%!$A)?A$G54#H,B'G$D#2!7;H9?'37+(10)>=<48%E/3<-(=H17H/!>7,$9+:A4?,>1B=?8F9&3"',(!F$+-7?E65B>>4=H9*9#*29+";,9%=@:;0.#07':6)G%:*8820<;51/#%F-@H3$!B0=A<,7@.A<?.B$+E9?'HH.48>)#<H9#21#?*E>$&4310C:*?E"07GA3;(C3&D;@45H0C$8H6F.E-5:57#>E4-2"D,)C7D$3),#F>76$98-1?/;G//&$AG!&7>&9?E(&5#54>!:7C64">))F?$!0A>@3?C70%13(@E@6$,-.
@r5263
CATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCNCGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGTGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCA
+
6AC=/9'+>.0:C4%28$F%<<?F$#!.E0BF9?GE9DB-0-H/G7#/)H3.3<"C=8%+?D?G#21?/20B*!,B,>15*#=,FG'2<;"9>D)816CE4771E.=3)..$F,B4%=!?#2=:0'7;H*G.B0/<5*"2;B16-##:F(3'.2653E<B@";80)"392!-D3*8%9G'@ABGE-&DA'E?H+/'F)-?9-1CE>;('01+9E2>-<%36G@+-H)GE9-==G7,(!<7>H,(4)=,!!10,#!"*=G"E(F8F9=0!"G(B.C$#<(.B(AHE?E4?2)%$+:5D";*)<B"5-A!-2!D-/B#)+"#,6(8.GE(=3,!-1-=2/!0$F:(+4E7HB78E!B15G$:<,*H0G):(#EC(HA41"DE+A0-F53$*6=>E08B$$./C+?0#18+22C9>08><
@r5264
TAAATATTAACAANATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTNCGTTTCTGNAATTGGGCAGAAGAAAACTGTCNATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAA
+
.-,9A6:E0,91B*.%,<7@B,?2$$1:+6;>0))$-5$210A>%G&()!#6?",8G4+>)?5>C%&5-(.&"?9'*:)<.?=5>'(0##B=;.?5C1?GBB62>:/,C$.#G1!59035494/2C+7G$9F2F?3(EB1>27'4(7B1$&5A:*@&:G,H9'&+*@4*%1;7$/;.F"7"7E>'H';";40$0@5?>F!,2%.@&;A$?%@()$/DE(9A"H9*%F7:C!.10(@>79";=%A8/FD'D5G#?<HG:-D830>956:2!(&>.<3&$3D+A-(DE>3C<%!+!/%$9
@r5265
ACGAAGNANNTGNNNTNTNNNGTGCGCGCATAAAACACCTCCGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGC
+
*($('%*"%"%)#$'&#$$"+%("'*&)%"!'*('*#(++(%!!$"+&+*&($"+$"#&!!)+((&'%*$+(+"!)+*"('#'$***#&'")+)*&%$+'!(('"$%$+%(*)%)&#!'++'%(%$'#(((#)(#))!"")!!#*)'!+%%)'*&$!*'()"((&%)!#!')+'*#'&"*&&&#)!%"'$+")!+"%!$#"!)(&++!*))&(%!$&#&**&$&""!*#'&#'#))+*+$#!+*(&*"'+%"#)#&)#!##*)(+*!'%!%+$##+&$!"(!)'(&
@r5266
ATTTTACAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCNAGTCTGCATCTTCATCATCGAAATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCANCGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACACGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAATGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCANCCAGTACGGCTGCACNGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCGATATTTTGTTTAAACGCCGTGGTCAGCGNCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTGTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGNTT
+
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
@r5267
CGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCTAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAANTCAAACAGAANTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGANCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTNATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTNA
+
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
@r5268
TGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATNGCTNGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCANCACCGAAAAGTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGACGAAACAAGCATGTCATCGTAATANGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTNATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAANATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTAGCTGNATCATACCTTCCGAGCATTTATTNAGCATTTCGCTCTAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTANTTTANCTTCATCACTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTNCTAANCCTATCTGAC
+
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
@r5269
GCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGNTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTGATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATC
+
0,#"D&($=$&.$",?>2')D<52-3@'1;3=B$%/C".!8@/5"(('7=3''&<54#HH:#G.C#?=C(8@B6*#B%<7B$'@,;**#)5,)H,%5!0H?G#6>%&?<%$*.@'2@;1>@;<<001&H<5.>**=#+54,4?4:?4;2.E8?A9:+6@;$@(0$A(8#AD&EC$F.8(4GEB.8)5=G2B#)#C2*;;C@048/7:
@r5270
TTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAAAGCGATGTTAATTTGTTCAATTATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAAGTTGCCCCGTATTCNGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTNCGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTANTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATAGGTAGATGATAANCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCNCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTA
+
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
@r5271
TTTAGNGANNGATNAAGATNTAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTANTATTCCCACTCACCCTCAACCGTATTACCCAACAGATCAGGGATTAATGAAAGATGGCAGAC
+
&(')"&'(!!&$(!$&!*"%()&(++(%&((*#+()'&+"!++'$$!)$)''')#'(+!*$$)(*$)"+%%%*"($'&*"#)+(#+"'+##*$*&)+(+#+*+($)('*!%&*"&$++((")
@r5272
TGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATTCNCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATGGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTCCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACNAGGCGTCTTCGTTCATCTATCGGATNGCCACACTCACAACAATGAGTGGCAGATATANCCTGGTGGTTCAGGCGGCGCATTTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTTTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGTACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGNCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCNCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGTTGTGCAGATTAATGACAGCGGTGCGGCGCTGNGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCNGGCGCGACTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGANCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCANCGGGAAAGGCTGACCAGCTGGNTTGGTGAAATTGCCGCGTATTACGCCGCAGCNCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATNCGGATAACGGCTACTNCGTGTTTGAGCAGTCACTGCTGCGGTATATCGNTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGACTTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTGAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCNTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATCGAGCGCCGTGCAGCCGGTNTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAG
+
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
@r5273
CGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCGTTTANGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTANGTTTACCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCNTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTNNTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTNCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTNCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGACTTAGCCACCGGATATCCCACAGGTGAGCCGTGTNGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTNGNGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATAATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTATCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATTGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTT
+
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
@r5274
ANCCGAGAGGTTCGNAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCACGANAACGAGGATATTGCGCTAACNGTAGGGAAACTGCGTGTTGAGCTNGAAACAGCAAAATCAAAACTCAANGAGCACCGTGAGTATTACGAAGGTGTTATCTCGTATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCC
+
%"%#&"+!'%%&()'+"(*")!!"%&#'+%!$#")'!%''"**(&+"())*+'(&!#"%&)*+!(!)$(%+%%%)"&%&&(*"!(+'"*$#+&*'$$"$**"$"%&"!("#"%$**"+%$'+%%%'&&)(#%+#"%#+!%+#+*%&))$*%++!#&&%+$%#)#+)+%+'(""'("#&&+&!%#'!%)())"$((!+$&(*'(%'+++*+"()'+"*$)*!"*!++*'!+*$'("(*$&)(*(!#'%('%$"')##)!*&(&*+'#(*#"!!#!*$*(+*+'*&&$%'(%&$$)(+!#!&*)!%+$$&$%&!'(!(!)!&'!%&&#!+%+"
@r5275
CGGTNTNGGCCNACTGGCACCAATTTTAAGGCACCCGNTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGNCGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATANGCAGCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGAC
+
'(("')##')("('$&('%)'%!#(*(&&'$!)'**#%%+'%%&!#+(%+!$$$%&+*%"#+*#(*'+'$"&*&!!!)%!'(*+!+"#&$**#!))%%%'*"+'(+"$*))($*%%"#(+&%#&'($%&#'$')($+"#'&()&))$"(&+)!)(%'+$(#+#$(&*'!(+%*%+#$(&&()*&&*+'*(!&&%**#)(#)&$'%($+()*$""&#!&'%'%"))+&("$!$+#*!)'!)(#"#)%'##)'#%*'+#)"$(&++#''!%#'
@r5276
GGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGNTGAACTGATTGCCCGTCTCCGCTCGCTNGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGANGTGGGATCAGCGCAGCCGGATACCGTGATTCT
+
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
@r5277
ANCGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGTACAACAACCCGCAACATCCGCTTNCCTAACCAAATGATTGAACAAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGNCGTCGGAGACTAACGTCAGAAAAGAGAGCATAAACATCAATTNAAAGGGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGNACATTGCAGTAATTGAGTTGCAGGTTTACNACTTTCCTGACACTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGAGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTGCACCAACGCTGCCTCAATTGCTCTGANTGCTTCCCGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAANTGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTAAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTG
+
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
@r5278
TAACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGANGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACACACCCGACGTCGGGG
+
($+!)#'#'!'$"+%)$%%(%#')$+"&'!$#&$"*&*#&'%($"'+'!$+'(!"&(!!&&((+&'&"))!$$&##'#%')&'!$"!#&*'&!&""*&####%&**+'(()%($#''*#"#&!)#!!$!()(*&"+#%''"$'+*$+!+&()"+'""(&$"#**"("%"'!"(#*$*%&"%!$"%(+&$)&#)#+"#*%%$+'"$"")"!)#!!+!))(&!")!
@r5279
NAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGATACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTNTCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAANTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCANCGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAANTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTG
+
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
@r5280
TGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCNTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCATGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGC
+
;&$BA#)#8:4"%$4&3#%GE6?%-D::;GH;8)4@+C#B>18!%!%8<95.%@"F,2A@--<#E?$1G6!0=@$EE$9%#-)=9.)@A7%*4","'59@1&3B-!&#32&<,B#E1:/9>!04?4!86&*>FB@2-+D*?&B;.%E4+@*E5B$;")D-@+&3
@r5281
AGTCCGCTGNAAGCGCGTGTGTATAGCTCACNATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAG
+
"#&+#''(&%+$$"&")"#$%)()#"'(!'#%%'$))*'*!&#$&'+++!()$*"+(*+$&'(*'!'""'))')#$)*#$$"$!%"!#*""'**'&"$%(%%!*%"%""
@r5282
TAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTANAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTANCGTTGAAGAATTTAGCCCTTCAATCGCCAGA
+
;<7+9-=8?E4")94=5+*@C6#1F&?;&8:&<D1*7&@F=HD3B:#(<.#&7E/+C<A"03=4?6E(C@'F1)8#D/B@+11B;&*);D@2:(:HF??8"#&-<#%*E8A?A*-C"AG&'2?/$;.31!D4B'?.$4+5=CF*#B=&$*4($-43(CG)?,#=GG-&E#%F;=6&&>H!=86@26D8%8*2F
@r5283
ACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGA
+
F!5-9C4"-3@9(7!E2#0C90#H(B(/7$.3@.9@H#G%+#6A@F$F"%@'*?8)6H?+#
@r5284
TACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATG
+
>1ADF6A==%:!FA/&$H1+%BB""0;DA@)19<:6H0?"A$8E-C1*7ABD$&GG0)9@16
@r5285
GGCAGCCATTGGGGCCGGTGGTATGACCGGCNTCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGA
+
C5%!GGB(+/E&&7..6'4C/HA=D7D(=)%F77!2'!'1F4-8!@29..F2F'-$"0-!%$=<?'EH$!?#F=*@1(8?
@r5286
GCCTTTGAGCAGGACAATGAANCCTGTNCATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGNACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGT
+
*+D0"22F42AH73C%CC"32%D1C1!//3%A*+>8;(%E0'57H$?9!)<&.C3;*)(1B2+@##E2;(<4%%4D)-ED*F*$GC(E(,+3C?51.@&%$"C)3&9%4FHA@&@&5B/B@?,7'98?GE;+G0)C?.3,)18'F*BD
@r5287
AAATCCCCANTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGAGATTTATTTTATCTGA
+
+!*!!$((**+')"&#)'&*$)($++&)#)&!$%''()"%(*)+"%&#&!))+%"+!((%+#'!'+"($**#"""#))%*#&*"%!!(#%""+*"'$'"(""""*%)++*+%('!')'(*!+"*!)'%$$"*+#*!+(#&#%'&%!#"#(()$)$&%+!%*!
@r5288
NTATCGGCAAATNCAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGAAGNCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGANTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTNTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGNTTAG
+
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
@r5289
AATGGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCGGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAANCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGAAGCACTGACCACCATGNAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGATGGCTTTGGGGTGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCNAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGA
+
&$(")*"*&+&$#+")#'%**"$*+'(%#&($!$*)$&!%*%!($$"!)*'%%!(*'##)$*%"!)&&"'(%#%&&(%$%'$+%+*!%"$+%(%(#!%+)$)$%$!+%)'*'!'')"')!+#!#''++$)#$+!#!$#$"')#&*!##*+&()$!&)%!$)+*"$&%++"'#%'"#'%##%)%%+))$$(+*%)&#)**)*&'!*%$(")'!$"!!!+#%+)+'$+*+"$)&)$)*#(+&"((#!*$&#'+"%#)$(!(&$&&"*)&##*"'#+#%&($**(&$&*'&%'"+)(*$%++#%)*+%"&)++)!!!+("#)(+!&$'&"*&*&'!""'&#&&!)(!&&$##'#+&"%#+%)")'!*+#%"$(%!")'++##!#)++'(&%!')*$%!&$%"*(($%++)%$"+*#'%'!&('#&!+"$$*%'#!$*
@r5290
CGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGNCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACNTAAACATTGCTGATACCGTTNAGCTGAAACGACATACATTGCAAGGAGTTTATA
+
1><G-?GEB/==@-5E()3C28+><$3DF:'7:!%GFA((1.:7(C,0#073E;<*?C3)95?6>G423+7/C/%:);H//%,59C"-G%GFF.EH,D#=0;A7;26,B#9?62@:#>)4&?'C-C)=A)*3.*?9?,,A)-2A$;)$45&E/4!,)0*-??EEB,(A=
@r5291
TCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCA
+
2A@>9$1HE.5';F+1<1?)$8A/?@%@!#)G$F0$F/%9
@r5292
GCTCTTCGCGTCCGTGAGCCTCNTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACG
+
'($&*%(+(*")!)(*($*('#+*$+!'*"$#''"''$+(""&!(&$$*!"&"%*%)(+!$#*%#'!#$+"%$+'$'+%%#""+*)#%"!$+
@r5293
TGAATTAATCGAGTACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGTTGCGGCCTNTTACACATGACCTNCGTGAAAGCGGGTGGCAGNAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACANATCTGNTTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAAAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATNCCAGAAAAACATGACCTGT
+
H>-=-=7G5(GA9=#@HC#"A(H#F:6,:<G91-C=@2$6@&8&'#037:@BF,!A5&A+D;9<;)"=G1B=B5<2))H8B7<*6&#C-F+)101D61-:67>?);)8"H<0B">82E/+'F(.2.6F;0,/!+0G;-G#2G@*G>F%-,5#2C>6B:EGB>"6<-1=6,(C-E0<16)1>BF9'9892<),:E!*DEH?;BCA,>4D#?%G&G/1"5>4=-,3G75H4A8/12=&+8@;B+5*<*%D7F#42)5?!#@>:>@+*"G+822)9ED(*&/>%"+870"B.9=+AA-B/ACB1=0*(GC$/-,!-"):'9,G'/#,$.&"D2B*<9?D.<$=(!(A(*B?3#
@r5294
GATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCANTGGCCTGAAGAGACGTTTGGCTGATCGG
+
42,%06?&109=8H13=6EE:60!/(C-0=!$AA,45.*2B%!%!1H1G*:6B?:07>:@9$E899/<@EEE1!H5AB*3H$>,>$8>50A'88EE/8-.E84<BA-5*D&09)((9C.>:E')5(C$"5@G+0
@r5295
CTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAGAACCATTCCAGACATGCTCGTTGAA
+
/H?'/#A:6/E$>$-?F'<9'&C'E.A=6<0CD<DA<6?!F%4#+#;)>@48>?0%?1$"!)$H218?8EH?;2#<'
@r5296
CCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGNCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCAT
+
@/H((>.6GC=008FA4B63?(&/#.?0'#),/H97>#%;E<:C=;!F,$?=53F%G(&<9;1'<C,9$C+17.=)7(B@"/)#;%D3E&@C*(H*,82;7:BA8BGA0B7;"58=?F!>E"'69=='2+9/G0?<G2"'9E!!=!H@3+B)9(B,;ED;7.
@r5297
CGTACGGANCAGTCGGCCAGCGTGGTGCTCTTGGAAATCGACCTGACAGAGGTTGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCNCATTCANGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACNCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTATGGTCGGCGGAACGGTGGTCNGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGANCTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTNCTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGA
+
*#))+*++*$'*("&'!!(*)+#%**'$++((*'*"!'"*"%%$*')!$&"'%%+($$(')"!++($%'++#"$&+$*#(*!"(##*&++(*(''!"&"'''+)"&#)+(+%#+"&'&*'!(!&("*+)'"+!&*()+'"+!*$'!!&#"#!!')(#!(!+''&&'")$+$&($(#!*+'"#&'*(&&#'#"$!$+#*%(''!%#*!)*&(&*!%("+(&&""$&)#*$+%)*"()"&+(!%))!%&"!%&!##))!$%*)'(%)+$$#'$%&'("+'*%)%*!%"#!+(!(($+!$%$('(*#('*#$(%#&%(!)!''!*+%!&(("!))(%#*$!&!&#('(($")&%!*(*%+$$++%$"*++(*$%+)%+%$*$%$("'#)$*$*!+$(*+)*$$+*$$($%'*"#''!+""%*!+(+!!'#""'&(*&(''"'("%('##&+$'!&%!')))&&**!"&$"##""(+"*')+#()"("&)$('##)(!'#'"**()(
@r5298
GAGCCATTGGTAAAACCTTACCTGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTNAGGCCAACGTGCTCAAATCTTCATANAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAANTGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGNTGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCNATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGTTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTAACTGTCAGGAAAGTGGTAAAACTGAAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCNTTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTG
+
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
@r5299
CCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTNCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGG
+
==.0.)5&E'@>>;'<A9*B*#B@.#89(>+(@"!%41*.F5:B*H"*10-%4H?#-8-8;FB!,:%)H&@57EGA=&,,:7D(0$C,&*3!<?-9E"=B:D*'E*-2>:A"=9,2@'.(3)E0;5B
@r5300
GGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGNCTGCAAGCTGCGTGGCCACNTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGNAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCTGCTGTTTTTTTCGC
+
6".58%%-#80!4*&0:8""<H-%")>?2#0H):C(F,==!'BH7<G+$:4=2!00?3?A.2%==>@G<:3)"*7A)A&:(A)*E.!9$:E-,5!F8H+H@?>#,':3B+G528@#3':?"A$'(&3A1H6CD;A$6%/$66CE-.,%ED(8&;81F+6&<#7;F:<#/!?A;G))B#;3CF+9*=1//,#7536B<D:7=C/@**9"899,?HE1@C-8682(!#EB"E05%E*@112"7?B72"@!H
@r5301
GCNTGAGTATTTCGAAGGTGTTATCTCGGATGGGAGTAAGCGTAT
+
(&%'5#:4!$AH(;2:0&E34'945F+!+/4#$"A=70H9"3A0$
@r5302
AAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAA
+
G(<,4,2)<5;$H6C9*!A,;BE??'11,C24H+@B.C#=+=38/*>4.-2"*&&"+4
@r5303
GATGNTGNTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACTTCAACTGCACCTGATGTTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCGGCGNGTATATTGTAAAGCTGAGTATTGNTTTATTTGGCGATTATTATCTTCAGNAGAATAATGGAAGTTCTATGAC
+
#)#%!$)"(++"$+%'+!#$&!&))(*'!&+)&)+''&(*)$!"#$'+"#)&##"##**!+((+)!'*$))#&%'+(!#'+**!%!)%&!$)%$$'%(%+%'+*+%'!#%'!%)%*!%*)&!%#+!('(#&)$$+"*#!##%'"$")!%"!&$+$)'!)''#$(%$&(#*)(!+(#'%"""!*(+)$('&""(!'(*#(#'(*#()+'(")+'!$#)!)''+"$%%#(%%"%''"%!#*"!*")#*"%*""++$$)*+'&#'&%#
@r5304
NTCCGTTACTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAAATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCCGCATGCCACGTAAGCGAAACTAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCA
+
"'&%+!++$(*+''$*+#)#!#!#)'&%+))$*&!("'+&%%*"'*#%+$"*%%&$*+"#***$*+&%($"$$+&+&(*#"*"*#!!*'(#$*#'#""%)%%+$&$#(&(($#%*$)%+')*!+")$+$##'(%"&&#*!(#+&%()#$%%#&)#&*(%$#"#"!')!&)++")#'#'!'+!(+%!(!%%)$!!!&+(&"'"'")'%%"*($+%)&%"'#!%#*&**"$!$$%('"("")%%*+&##!#'+*"')&'"!&'""#%'!&!%''&()#*!!'$!+#$!(""&"&"#!'&)++)!(')(&+*+%$"%$&+&"#&+#)%'$%$*&#$*%#$*%"*%((*!$!+'#!'!$*'+'%%!$%+#*$*)+()&!!"$!!&"++*#!!$*+)'&(('**+"'"'"&"!)
@r5305
ACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGNAAGCTGCTCATACGAGACACCCAGCCCNGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGNGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGG
+
<2G65,@3@,52F9E&<@56A5.A73,C8E%FB,&.;@;%%7?@=A>4:8,#%0-/C$/2%$7A,4/4G2$5G/5B4,@<-(*+)';2+!F@3BG("32A<A6<(51(-;0@H=>!<'&$H52#<DDD-5%00F!=:A2H4.%5/G5(57:'05/2)*@3=)B5!>&29:E.,#BH#8@42&H&1&9D*,?H-A;D>+9%0,3>8#-(+17*<@'0(3%0A5FB!'!=51-<#20D#(9>F4.<%>3"-*H0'3$G@7/>&#@&3$;4*)C+*3B.8:-44<AH@0D$')&7HH373?9(..*G)5"?"5&47=0#EF
@r5306
NNTTCCNGTNNNNNTTTAAGCTGNGGTTGCNTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTG
+
!!')'*%'*#"!'"$*)$*!((*$+&"*#!""$#$)")%#%'%'"$)*")("*#!+('&+"%!&!+'+"&#!%'+"+(*"!*&!
@r5307
GCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAACGAGTCACTCAGAGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGNATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGC
+
A1H$0,&3A&(AD#9'!&+CD61HB(EDDF!%'7.AH0)7!@':>+(8F/>6&><'*3";9B=$H"$E#*&,5!*@25>/"%"'2=!C(D,,:$'A%<=:6191C4>3<:G5;5><C-C8=5+(1;$2,7B+>2-8E6A8*!53'(.9,;2)0$3.*'ED)C)+.:3::/-=#*,>%330($8!C/?90?6/+4CA2H2665-3>4F3687HD@?<@6B,,/;#')E@>'F:26#6/-E$0869(4BF&/!:=,=(;&9#,6H5E;:"8;B)*E><=B%B601+./:2EBG0C15*'8H<'H$6AAE=+5!A"<7,G8@>EG=4)GG%74:*:5"?&6:;*0':$HEH(F#/>*;AD=*E0*C=6G,A,%:*A+!=E($BCG"3A&:-B=B65.6CAG=GA'24)9F5D%%8!6)<=D=&<"
@r5308
GTCAGNTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCG
+
+&"%%+($(('$(+#+'%(!+)'%*$$#+)+'+'*"&+!$*!&$'"'#)$(&'$&%!"
@r5309
GCCNCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCATGGCAAAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCNGCACCGGCACTGGTGGCC
+
=0-D;CD=7G/=/*%><H-)G@A6,""@3"AC67:/AA%&.>=1!<F+#!#:;C+,(&?9E:'!+/>5')!'662*387.4$3'9<(-?00,F(/=5&#:#'0#!C>>:&,3:4HB?0'4*:*6%H7A::">9,9BH0#%B?04&DDFC*;CC,*C'-3<7;*+*BF64<EE':3<9*&B,13,A.B='EA130((6&55!"?BBF.%4E>#=1!?*?7$G#(17(&(-$@5F15'1"7>-(+"E8,#9:DF+"FH5+G)<D4:)A?28*46D%$+%+4+16=$.*>.@6+&5A=C>
@r5310
TTCTTCGTCTGTTTCTACTGGTATTCGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTANCTCAACAGAAGATGCTTTGTGCATACANCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATC
+
*1*#.@&(,$*%8"1;-3,96!(=!60%AGB9+$'F$4A=/=!?G48.#+G$:+'*;,BEC!C;AH++++3(=?>3602.(#63:6;H,D+D%->3D)$GC#>0<DD8.)/95-E)<553$&:9!'+0>%<H,.!D!BA8A5<7,:-43.E*B-2A8',)5/4@$&8<(8%/F.3@E;@/.6:,E2,)=B88!)(GB4((2/B?B5;-!1-%5-HB,;G/+$9;7>?2.*0%;&+B3!.G$DD/!:=874HG2)'='%->H&-C
@r5311
GCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGANCACGCAGCTGCAGAGCGCCA
+
,"%'A-"A(8(;+2*EB3%A%#9F,:8@#%:,1,(!1G0)63E<G=1;*-/;7<HEFB1@&C!B.$'E7?/<G-9>
@r5312
GCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTGCCGTCGTCCGCTGTAACGGTCAGA
+
'36+=,:%.4G'-+)'!:04'4%>B@,.?81%-;<0>2#'0>!?;(A:>DA;;/:<9BE::5#9@69+;
@r5313
GTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACN
+
6F62(?=2%/);=''F7)A<?,,0?12?"5BC3@,-34!<02&4D9F68&
@r5314
AGGGAAGAACGGGAAGGAAAGATNAGCACGAACCTGGTTTTTATGGAGTGTCGCCAAAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCT
+
A8.!;$9!'025B0C*%B)8!-$>6#,9E)).&7+H.1&'7:$B($2*4E/417)!+!G?6'H0>F2&H2?.@*HE"6+6BA"<5.$,B67GB+!6DE=<D-@3H)4-DE)9A@#&0;47*2(*$<<:"$42"=.%*%:H5EA?;8,)7,'*#"'A=2?>.&4/F=)E"78C?759:09/#!0*@.B1H1@)6(GH.>D2B8#3D9A+,(>-<6;A8$$69D.E'%5'<.?!>!C0E31-*@D@G#8;+-BE;&C:99%"2BD)0A78F3*GD-C;9-;?;='H:6*8)"&,D?>06'-1*F,H<.(324$8-;>885H(!)*1'275,
@r5315
AGTTACCTCTGCCGNAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTCNGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCANGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCNCCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCATCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTNATAGTTAAAAAAATCTTTCGGCCTGCATGNATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTT
+
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
@r5316
ACGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCNCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGTCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACNCACCGAAGGTGGGGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAANCCACATACCGCTTCACGCAACNGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATNCGGCGTCGGTATCGTTCCGGATTGCNGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGNAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGNATTCNTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCNATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTG
+
&;G=187C#&EF8A(F9H/)60,2)B="*'+ABE<5B?$:;)!FDA$H2+*A71?'@B!!+70)<?!-H1A4@#;(A*;,2?*F)(&77H93#4E-C2CF=$5#')1<.@4)*!D+6C%)#FE66?G,$55@$@E/7F)0@FB8,"?"*-)+*22/A@$0#2"316744-6<>0'.?B41$8G*"9=01-):&<4)AE/B7CF:--D45)6;$+10-*"9"*?F:F(F=3%748,,@EG540C6F-&6(1#!#"%)1@HHCA5'5160?7-&$%-/09'48&%F5BF:(69>4#2:4#+66/*6G*0/:#E#,6?AC2$'H=;@?657;4;;"3AFB"0=>/)1":<=0#-'..%F7CDA@8,;#/%=<C;?G25)."#)):/(<#+C2<6/$3*<A34<F=$&03?%+'''E'+G1')8D-;08&'7'+5$#FBA*2BAB%,?A771,-=7H(2=(89;DD+>0E0$399?45.6!0%"0%>6"5#6'.3G;4#AAEAA*,/,'8/:E08+-7*$B++,27+?$66?&G$)00G(35DF478%')9$A7A&(+E07./F/AHF$<0%-A%6%,:C;*<5E96,0445#/#0(AC"-4"+C#!#'G5!"/F/*>;"3/@;>>:+@'H@6(.:A=.1'2:/G/2"/",>!":+88'1EHB>)+)GD)-,5/@*2=)8<).0>>8<?508@4D25F<GF&1F%$@B<?$6)!=%&;0$!E%FB*0-C82-"<C%/2:DDHH;0B:.@="(E:6#G977>7:&)/"CC(3*G?@+6C?F(1-=H$>&6"HA*C8A*8==F-#A+,8+$1@DH5*F;!;H/:*HC-7>!H+?9G*8-H8H;D-H*>>C0;4FA88G'05"$,5C).9D+"+?ED%%?.*,'/6<.D0-:9)59H@#D!.9>3($DC/5/:>B7H1
@r5317
CGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGGATACGACGGTTACCCACCACAAGCACGCTGCCGNCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCAGCTTGATTATGGGCAGATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGCNTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATNACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACNAATTAACATCGCTTTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCNTCGGAGACTAACGTCAGA
+
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
@r5318
TGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAA
+
GB3/):AC/=%44B3./H#'/&G)2GD7E0B&&.478D@6;/(B>$(8="A1F%5"6?"/C>*&425!%4A2&F*>(BE:=25/@+H&&+<
@r5319
ATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATT
+
A'F!)&B2*)!G.;FB2=D!$H$>/7&78(8F<HB@,8!(F%AE3HD4-%=)&8#?32#=83"
@r5320
CCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCNGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTA
+
@A?B775*E06D/("$'?5-8+D;H0ED#-?+1/>3?%$8!)52%*&)95,&)+*79+%+"F-8,"'!G%45D8'%%G:;)8D;552#?(71E@%>@%H;.683.++1=#F7>',D2!5-9&!!F6D6"B>;G.$.*:5*$;;:<+6$7;$D$;66:9?HC8<A76-/'D4?3;ADH.<+7769-,G1"71,&.7"('#-C('1?0@2+48D*.'HF%E:5=$H%,6-/;&;51G=:,;=1D"-"$B8@5:*32)E-C<!/
@r5321
CCCACCGACCATCTNTGACTGTACGCCACTGTCCCTAGGACTGCTATGTNACGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATNATATTCTAGA
+
E$5A9*$#2A6-+C.'7=E6/6?0-GDD:D>G%01)@+(/%4,-$990EFDG6&F1$:6H:@7=#,1:FGBA/+'9B421%/GGDF5136>ED;%1/3805C/>1'2;,&>)==?:'C;:*)8#/?,!=:D@1>'.G&+(72#7$-$?G13E,H,0!=):A3@)D>.G7$(,C1##(!:=+A+(;E;&B8(>::CF.=1-FC)@%5>.7"H/HA.74:-D+;?/:
@r5322
CAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATNCCGTTCAGCGGTGTCTGCCAGNCGGGGGGAGGCTGCGTTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGGTGNNCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAGTTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGNCAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTTTGCTCATACATCAATCTCTCTGACCGTTCCGCCCG
+
?.(467?")"*")G6;.+12=B%.=78#'D"&F)B0=%F/8,+3#(#.5H.@?<D.#F-0DD..2+D.E)EA$E<*@10@A9GAFCC@2=&0HH@#31?&)4""#BF?!06/"CF1A:01"&8:E.5=1'14=7E5&1EFC7:,9"0/<10?2-$B2$<:A>2E"<7)21)?=>B4+F8':2=%)<DG27:*##81B64.>??!.9%3$'8H@/#1!C?,,>5DA6/(H=#+1H@G9<:D-H:G13)*1(H-%+='+(A'C:&G69F+0G3+-8;71;?H,='-55<)$@3AH$F73'D>)%81.7;.4(6:DC*#)/7,&3.3GC!&;,H:%0+?:)<9A"&"201F(#&)D$-"D28E')01!#@<)C/<,,-@6,+.99=/>+5,?9"7"51$854:?D6!0B24!C7552+1E#>2;#8"<+#25E*):G8=5+C=78=7G346+.2
@r5323
GANGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCG
+
:@?!("?A;00;.F;16DB%1-321B5#A/+$8*(-)/*?CF'DB);+=4)&75F680$%&'3$4&H>"$(G)=,65&8@47@&B0./"3619BBB&;E!16H$?+!<+%%2!E3F($?555C
@r5324
ANACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTNGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCNCAAGTCTGGCTATNCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGNTCATGGAATTACCTTCAACCTNAAGCCAGAATGCANANTTACTGGNTTTTTTGGTTGTGCCTACCCATCTCTCCGCATCACCTTTGGTAAAGGTT
+
?+E(59H<A@1*97G&4@G:<108?5F<>A*,6<2/-;8F=BC*B7G+A3-5?&;004E7#;<"-7@(=B<)'=;(EE%F&'@)"!8.&F>!*A')+:1&F9,;7)8/+,1A<:.14FA&,?<)589F2%&(EE@F>&6.?,<:'3C#/0!)<GDG'AF'@&=)C5791+AG")?3F/,)A03787!?*HB@)%#:+A7><4F5F$9!&.B8A&>0=>F*02A9.")"<-%29$9A;=C&'6E,;-<::1;&A)C5,7CA0+8A@9,DDD+B(82B",A37BF=1F-,7-?G9"%B"295;;1)GA743E<8&@26?1(C37C!4@12%<A)*>7G;FEG)EG
@r5325
ATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATNTATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTC
+
H.DD,9.7!/85GD&0!$E#+CH8!(C&6*%6G'71F+.84DD&.177>7#F>37@;2/AC3$3&#/7G%B!C>A90G84,<!&#4"3#DD#H?:/*30.%6A7($/0@&/*22-D(-($.G>BA9B>B4(!7G%C6+"*?'<.G//2;,)B:C.=G#=1%=85=G*(>CH=!+E%5&"-.E5BB#8%H&#5!?&>-#5:;"4=0F0&G<<'/$/H&F?,?/="C#HAG&#1C,2,$&@
@r5326
NAGNNAGANNNTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGT
+
!))%!&)"%%+)+%$'%#)"'!(*$"&)%#"!!(()*%*!%(&$$!%"#($"!(*#%!+#%*)+$(%"("$'"+'&!+*)+
@r5327
TTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCNTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTNGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATATGGGATGCGGTGCTGGATATTGGTCGNCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCNATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGNTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGCGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAAGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGT
+
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
@r5328
AGTCCACGTATGACCCGACCGACGATATCGAANCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGC
+
+)("))'*!'*+")%%+*"$*(#%+!##&((&+%'(()#!!!##)'+$#)++)!(%#%*&!)!)$#&#&++"%%!&)'(%($"+(#""*#%&&)*"!%'#%(&("+&*'&*)))&)&!!)&&$&'$*%#*+%#%!!++!!&!+$)"%&%"'(&"+)#"!$!!%&"%#"$'$!"&!%""'(%(&*(*'*+'!%!%'*##
@r5329
CGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGA
+
@B*G0D<3.<8<5D;$?E:''"H;=B>'/"G%(+$*=/3&@!A>(G4C=:))20F+'A2(?2&?"84)BH:9+AHHB=%$G:8(DA'!.6('.3=%"6(298D/(C")'>%:B4)<)/&8AG2/+=2"G0D!.6G$'754,=.:B@DE;D87-@@*:&B.6B<7;E&E%55!->C,=/57)63#A'"$
@r5330
TAANGNNNANTGCNGTTATGAGCTGACGGNCAGTGTNGGGGTGAAGGCTTCCCTGGGGTTCGCCNCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTNGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGCTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCAGTTATAAATTNTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTNTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGGACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGANCACGGTGGGCTCAGAGAATCTGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGNCGGTTTTCCACCATCGCACGCCGGGANCATCACCGTGTATGAAGATTCACAACCGGGGAC
+
**)*$%#$&%*$'$)&)$*++&+*'+#%%)+!')+(%%*)*(&*!&%$&&*%$(!""+'()#&$((#*)$#&'#&(#&"**(&($&$%&$!((#!'&%'!*!*+*!(*)%&'%%)&*$!))#!)%$!++#"!+!+&"*$''*#(""'$+$*##*!('+&#)((*#!#&'%&(((%"*)%&)%*%'*&!'$+!#)($'"##('*$!"!!!'(('"#*$&"#(&)'+%%**!$'$%&$(*$%""!%)$)&)!!%+("%%$")%&(("$!#)+)""+($"&&$*!$)'!"$+)"$!$++'$!)#!*)+((%+'$!(#!#)"$$())!$)+$(("*%($#&')"#++*"++"'*%*%#!#(*!#*"%(($#$%"('!"&%"#($)+"#"%!$!%$'!)$%+$!$$+')!()"%"#%*+$+'(%)#$!(&%#(!+&!"*'"*&(&%'$'#&*&+!$('*#!+%*'#%"(%&)#'&)(#*&(++"!%"**$'!&%!+)$**#$+&#%*%+'()(!%+"!($(**'&++'%&&%!)%"+"*($"&(*$#*"*$&(')'+!)(++%((%!&&%")(((%)(#"#$%&"+$(+#'&+#'%')($$)*##+'%)+&())&&!+')%&*&*&(&!$!#%"!(+("(#'#$('%()(!%+#)$$'+('%'$%%(#!**)#"!+$"+$+%!)!(%$#*%+'()+!'''##"*&*)*!#$%#***!'+"'!&"++%!))%&#$&*#!$%%)%&$"!!#%((#&)&(+)&$&&(%*+)!(!
@r5331
TCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGTCCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCGTATCAGAAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACG
+
+($'#"%"!'!+(*$'*&*'!+*$)$'"&'%($"!"+*)#"*%("$)!+"+'("%*))((&%*&(%'%(%%)$()&*+**$$)#&#&(!#)%)+!'$#)'#&(+"'*(!')+(*+*#*(&(+""+"'!"&()*+#+'$&$!#"*!)"&(#(%((%%)'&+$+'%*(&)(((&#%%*##)&!+!"(&'+((*'&%""($&"'(%*"$!%##))!$#)&#!("***'!##&+$!
@r5332
CGTCAAAACTCGCCATGTACTTTTCATCCCGTCACNACATAATGCAGGCCTNCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCGCCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGNGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCANACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACNTTCACGCCGGAAGTGAATTCAANCAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGCTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTCTTGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGA
+
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
@r5333
CGATCCCGGTAAGCTGCAGGATNATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCG
+
*49-;..E33BH?H&82$@!D(:$.B%>#"'4DE7:08B&;H%!,#?)&6)E>#$4&?<%B/+E#5&90<:D#E8&,-!+.7A-)*1F=EH#$-1(574(%+%@C(/-0.(%G((*!D%5:@>%0E;B-9B"6<B
@r5334
GCGCAGAAAATGTTGTAAAAACAGAAACCCAGCAAACATTCGTAAATGGATTG
+
=6=/>=H$*6.7,C"CEFA)36@FE&C*<=-)@*9;G1>."0(7$B1/B"B?0
@r5335
NTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTA
+
'B,3H'9?@B1'!>=;#%0#E%*00E67**+EE,60#-&7E.&55)-?>/%6=6B&#F?'"%&:@E6'B53"<D
@r5336
AGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATNCGCTGGCGCTGAANAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTCAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGAAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTNTACNGGCTGATGCGCGGCTATG
+
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
@r5337
NTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAANGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTTGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACAGTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAAACTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGC
+
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
@r5338
AANAGCTGCTNATCATAGANNTGNCNNNNGNTAANNATTTGCCGGTCAATCAGCCAGCTTTCCTCANCCGGCCCCCATCCCCATACGCGCATTTCGTAGNGGTCCNNCTGGGAGTCGATACCGGCGGTCAGGTANGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTNCGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGAGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCNGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCNTCTCTTTGTCGCCAAATTTNAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAANACGCATAAAATGCGGGGATTCACTGGCTGCACGCTTAATCTGACAGGTGCCTCTCACTTTTGGNGTGGAGCCACGGATGGACTTTGGCCGGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCANAAGCAGCAAGTTCATCATAACCCACCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGNACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGATCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGANTATCACGAATAGACGGCTCAACGTGGGTTTTCATAAAGTTCTGGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCNTATGCTCTATAAAGTAGGCNTAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCTCCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGANGCCCGGCGCGGACAAAANGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCA
+
*#$&#$"!')""&*$*#)"#')(!)("#$#!!(%'*$*'+%!!&!('$*&$+&(!!(%%&&$!()%$()&&"'*)"##%%#(**&)!+'*#*%*"$'''#(%&)***$+&&&#+**!)'%"%%!!&(+"!%%!((%)&#&!*!+*($*+%&$%(&#(("##(*#(#&$+!(+%"!+(%("*'&&*$+'**%(*!#!%#!%*)$'%&%*&%!(&*'$%*+"))'((!*%((*+#!*&$'#!&#!%$&)&&$!!"))*+%'"''(*)*"&&#!+'%)+#"')%)'$"'')*%'()%*)#%%%&$"#(%"%!'"&()+'+"$*$!+"&%$&%*"&&#%&)(#'&(''!"+#)*'#)&#$(%)'+!(&!')))!+(('(#+##")&#!%'$#(")+!)#(+"$$(!!%#'$*"#(#'$%++#&)&$%*%(*))$)$&)%(*!$#''#&$"&'()'&'"()!++)#%$#'($+!%'##+%+!+#&$'%#('&)'#()!"""+*)+"(!))#*)(#*%#("#)*&)'*"&!"#)#'#(+'&)%'$%'&#)*"'(!+!+&"&("")%'"**"%%!"#&&(#"!$&+'$*+)&*''*))""'*$"')##""&**%(!*)!'!(##&#$!#)(")'$")!$$)%&%#$%$)($++*%+##*!'#!"*#*"*!(*$!$+&!+!(*("''$#!(!%('$(%#'*%+)(&"'%&+'$+*$'"+$!!&)"!&%+("("!+)$&(**!#!*+$$+!(%&$"(!+%%'$##*)(*!*+%$*%!+%(#!$"$*"%))#'!#$*#%&"#$(%%!&&")(!)(!"(!*$!&$+++())*#%)&#&+*(%(++!)"+$%'$#%$$)$+'!#&(#'++#(++!#)%'#%!&(#$$#(&'%'&'#*$&'$*%')+!*((&!*#$$%!'&&&)&&##!+$)))($*%#**!&")*!**"++$+)&(&((*"#))!#!+#+')#$'$&*)(&(&$+!*")'%'*#(*'*$$"+##)#"&(&!#)!)((&$'$)$$+(+"%#$*(%("!&*&"%(&(!&&')&'+&%*&"%*)%)!(()%)'"')))%+%!+&+%"+!+'"'%+*+'+#+((")"'"!%)%#')+''$(+&'+*&"'$&**+"'))'&&)$!(+))#&)*)*)%#!)*#*)"%($(%"$*$$)$""#+)&"%)$$"%)'('%&#(*$"#('+&$"*(&%$+'#'(&)'$!&!'$!$!*+!"&&'##)!#%*)$&+&("$($$')"''##(%"&())))'!'"+(%++)()$!!+)&')')!)("'!$+#%+**#!*)+#%&!!)#+(+*))*!(%"$+'
@r5339
GGGCGCGTCACTANCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACNTGGAAAAAGGCNTGCCCCATCACTTGTTTGAATCGCTATGCATCGATCATTTCCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCANGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGAAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGNATGGCATCGTTTCGGTGGTGGGCGTTGNTGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCNTGGNCTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCANTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACGTTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTNATAGCAAAACCCNGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTNCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTANCGCTAAAGCCCTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAGCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGNACCGCCTGCTCTCCCGATGGTTTATGCAGTGGCGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTNCAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGANGCGTGAAGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGA
+
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
@r5340
ATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCNTCTTCCATATAGCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATNTTAATGAGAGAATCGGTNTTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTNCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGNTGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTNCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACNGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGNGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGCATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAAC
+
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
@r5341
TTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGNTTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGANAACNAAGAAAAAAAACCGACTTTAGGAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGANTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGCACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATA
+
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
@r5342
TAAAGTTAGCGTTNAAGAATTTAGCCCTTCAATNGCCAGAGAAATCTACGAGATGAATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCNGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACGTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCNGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAACTTTCCTGACGGAATGTTAATTCTCGTT
+
!;.;>=1$>2.F)F13B3C95><>3)+3*6;425*(3*D*H%==CF4A#*+74&G:202$"7%'9*B<(5>8'1#H.&7:A16&28-G:+/=8*6">@F+9,/?,?4B',)35F/3H"==G@<<6-G%!&+.E/>,@26B#D&<.@@'778FH'G#8?C;H2-"8,2<C-2<;(%@6$6!H%+?99(E1G<!2$>=;&43''3F&7@!/A44D.E;".@::'/!!')F61>@AA+,))46,8)1>G(>=)A52?%.4E?@)/45:%1/C%9+>-A@;@$-.@68(H'5?1.2
@r5343
NAGCCAGCTGCNTTTTGTTGACTTCCATTGTTCATTCCACGGA
+
!2&1-E1619F54A9F3:"5F#"G,9+-1HEA83?60GB)97&
@r5344
AAGNNATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTNTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACNCCAACATATAGTAACCCTTAATTTTATTAAAATCACCGCAATTTATTTGGCGGCAANACAGGATCNCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAACTTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCATCCTTTTGGATAACCCACTGTCATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAA
+
*((&&+'$)!!+(%&*!$%+%'(#*'*#!')!*)%%!%#+*'(*&!"")$#+$$(#*(**''#%'**"('*&&#"$!$%*+)#&$+**"#("'!"&!#*&!"&&#(%"#+*(+"&(%)+&%)(!'!$*$%&*""%#*%+*"((!%+&)("$%*(&&)&"#(&!&!"$%")+)"'"+"$%#$&')*(+++%$+#+##%%"!#)!("!+$#'%+$*'%%+'(&&!')%#(*"")*"**'$*)$%$%%"($))!*!+)&&++#*!&+%%)!*'*)%*%*#)'(!$)!+')&(&)'+#*!&"&+$&%$#!*$'"!$)*#%$&!*#+###+!'")')'$('!(%$$'!"+'$"#("''$%!&%#*%")&!%*(%'+&)$+*'*)"(#$"'+$*')*$+
@r5345
TAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATNCATAAAATCGAGGGAAAAACTCTTCTCTTTACCAAAACANATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTNAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCGTTGGGATTNCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTNCCAGAACTGTTTTCGGGCCGACCAC
+
&A?;+%F%7=03'4%4)/)/0#:4?BCG,))#)B%E+FE*?:&3A,+(>?+HD/+*#+;?D*/6H26):)#*0;E-0)%+F=!8?!@!C%=%;B:<"HF!H020=6=?':'B6FH2<(0&C9"?-G@=0D.1,!<6D*+9%C!3'2-714$!5=!B@?4:6*?%;+A/5G*.:F&::G9/+E.#'7>-1<)422@G/<-#0,5/#&.BF%D)E33!H:H0H$4#3?)>DA.7G/-=A!)+B3=3@G"/D#'/(+BHH%44-H.#*2>17+7!("
@r5346
ACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGNGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACT
+
.)G<?%E:;0+$-81",H/$9=,5,A!CF0)H;-E.((H?.<'8>9-0'6CF5D<8%F.<>B'5C%0H#9*4/0/86#A%+D<.>@H2,A3;0D:0:#0#41+%2"!"&-!HF,"E<F3H8D--4=G(
@r5347
NCNCANGAAGCGTCCTCCGGCGCAGAAGCGGCNTCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGNCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGNGGCCGCCACTTCAGCCCGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACTCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGNGGCAAAAACGTCCNAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAATGGCANCCACGAAGGCGACAGAGGCCGCGGGAAGTGCGGNATCAGCATCGCAGAGCAAAAGTGCGGCNGAAGCGGCGGCAATACGTGCAAAAAATTCGGNAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAANCGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACNGGACAGNCCGGCACTGACCGGAACGCCAACAGCANCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGGTCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACANCCGAAGAATGCNACACTGACGNCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCNCCCAGCCTGACTGAACTGACTCAGGTTGGCNGGGATATTCTGGCAAAAAATTCCGTTNCAGATGTTCTTGAANACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCNGTCTGGCTACGTCCTGATGCAGGGGCTNGCGTTTGACAAATCAGCCTACCCAAA
+
$&*&&++')+*("!'("&##%*$#+)++!$&*#"%%+("#%#(%%*'$$#$$""+%%%'$(+&##!""!!$%'()#'$)!$(%#!$"&)'('!)!""!++*"+(*#"!*$("*!*$!!"'($%#"()!)"*$+#'(&&))!*"'$$*')$')*(")#**'*++(!+$'$'!'!"%%**%&&!)&"'&'$"'%(&!(!)#)&%%%($)*!&(")$))&%!!+%$&(!*+#%'))&"'$+*)+*!%+&$"%!#&&#""%#")"!)$*&#%(+((#$($!#'!)&%&(#)%#%"!*#"(#)"'(((&**#!(*%*"(&$("$'&!#!+'%')&#$+)!'*###*$""*(%(&#"&!!$)#)"''$+*)$#&+%!$%!'&$$!!"&$&#)"("&)(#('#(!"!$$"))'"#"*&*%%'#'''$+(''#)'&$'''%))!!("!'))#$%(&*!'(')%#(##&"!"&!%&&+!(''!!$)!(#"!!"!&)''!*("$')"&'#((*"%$!'+"#+'#$*"*)")%(')(%$!#)'+&""%#"""'%(#$)(+&%()#$)&'#"%&!&#)%""$!"#&)+")!$'!"+%+*+*#++&&*!($&"!*#*+#)("'!"$&*"$%#&)("&$&+&&$!&$*&'&%#$&$$$'"'!((!(+&*+#+*#'*'#"#)+$!)("$"$'))$(%()++#(*)#&#&""!("!!&+&+#&)+$+'*)(+)$'#!*#(!+#**%&+((*(!'&("")()+&'+("++"'"""+!'$&(%*&*"%#!&($++&*(()+$+#"!*#()#*"#"$***$(%#)'!$+)+'*#(+")(&%(+&!%+%+%)(%")+&'"($!!&(&''$'$'$$$"$$+#$*'&"'&*("$#+*$$)$$%*'$!)!$(*&#*#&$(('!()'"&()$(#%!"!+#%#*&+($!"'&+$"*+!!%%'$+)+'$&'!**&((++"$(&%)+#"+*'%"&)"%**&$)%+$$($+%!#*)+#&&&#+%&+))*+%)'+&%$*!&+%!'%'+!)$)+!!++$'$&(&$*$+$#+%*'&#&("%#%)$$%#")+!(&)$(%$##)&&$$+)*&#"&++'!**!)$%#($)"))#"**&'(++)#)!"&"+$&"'&*%+!%(%%#'!(!!&)'!"*)'*$*%)''$$'((#'%"""!(#*%!)'+&&&%'++#!&'!%$()+)!
@r5348
GGGATATTACGTCAGCGAGGACGGGTATNCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCNCGCNTCGTTCATTC
+
&;C#&G:&*H"/;:#F*:%'"D;.6HB.'4":4$!4G=F&5554=.=8-'B7F8C2GE9!)3BA#HC68%G")9?4?G38C2B8=:F$)/:81H/F->
@r5349
GTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGATGCCCGTGCCGTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTC
+
4;?#7-1&;>"<(9&,D2/%6D9?B?;4C<;70802A@A2#1%305;9/3<1E*64*$*#%3/#2--#!5&$>/,F1)0'=E/;E*A'7-%:-$<)#80<DFC(:0D1$#"%$#33A47?!B$H."AA'3<<)-,1>"C$>A9(<??:'3@9.#."?.@=.A851D8#!F(DA0F?*17/C<H@1#$6$!%8G!7:4A&3-*)/#C+!F-C1&E'%<3"BF4>BB@A-H&,"B6>'?3=(=+0%5@5E<!&449H'/+<>*<);5E,0-?F!=C757.9536,,7=D(2H>.8#.;B,A>*?--.@<$<&)9E=3D'/6?@);+"-F*>$?3),043EF
@r5350
ANACNNAGAGNNNNNTTTCTNNATCCAGCCAGCGACCATGCCATTCAACCTGACNAGGGACGTCACNTAAGCAGGCCCATAGCTTCTTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTANTTTTTTCATGACTTCCCTCACCCCCAAATAAAAAGGCCTGNGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCANACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCNCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTANCTTTGATTTNTGCGATCTTCGCCAGAGCCTGTGCANGATTTAGAGGTCT
+
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
@r5351
GTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATANCGCACTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCANGCACT
+
-03A&0,*GH4$!!?*</!B*%HE)=DG%*4C*8FFB;D9$'5C>#"3,FD$=)+?F%3=-8D/@)4(42@$/$;C5>1C"A#?*E*CA/>1<3:'C8:.E>&B!3?-!C;G(33-.47B!,/
@r5352
ACCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGGGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCANCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATNTCAGCCAGCTGCTTTTTGTTGACTTCCATTNTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAG
+
$!%+*)))''*"%!(&$"**%'($+*%"(%'($&%$$$#($"'$%!#$!(+%!'&*%$$!(&*"#)!&!''#"*&(*"%!('(+'*%)"#((*&*&++)%(&%%')#&#**&!%'+($"*"'+&*#+%*$!)(#)#+&&')$*&+)#)(#+'(+"*#$%**+""($)!&('&&#"+##&""*'*$)+!#%+&(!)#+%$*'*(!+*#(&)"%+&"(')&$#+*+!%$')(&(+&((&*&#$$#"$"&%%!**)!*+))$!#'*!)*(%
@r5353
ATCCCTGCCTGAACNTGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCNTACTAACCGCTTCATACATCTNGTAGA
+
=+A);(6&B<;9$0E*H)3)3@A+*+F2*B.#'2E2@"<>5%'H7AE;:)?"?,C?4@.23=6#?.<3F)(5!@3G+13+0"DD,55B
@r5354
TTTCTCAGGCTGGGTCATTGAAGCCTGCNGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCNGCGTTCTTCCCTCCGAGCAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGANTAGCAGTTATGGTGATCAGTCAACCA
+
D;=H4'*+ED12E?E&H=#5;)(2(:9#('2D(4C@*9G)-BBE'B9-@E5015%8-G32/@(=(GG,/>'AFF>,>):3$./'<85C-:56<.45G#6G12"$!7+41A:4*3&/7%-<14/;+.,E,1-)39'"E5B0?/?$!A5B#65&**G)/7-528G(B'27>$5/GB4#GA5>(*0C46:=&*@)?8C%;!*/"-3<'0>F@"H3AB51*5EB0A4--':!H+DE''5.E198F=.H3H"7,@&@+(=;,/9BF4,
@r5355
TTGGTGCTTTATTTAATGGCATCAATGCATTAAANGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCG
+
7<58=??E0$H-C;0.4AA<DD6.AADA;;&0BH8H4:F/#0>(<H+@DB&-)93/F,$75=$6=3&+'3H(,#@,,2<.=9&@5":&#;;&$//8G;#=F!BB09(/==++=&8..FAH<#:B3C%!?#/2@9>//EH%<;:=">
@r5356
CTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTNGTTCCGGCCAGCAGANTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGNCGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTANGCGCATGTGCACCGGCACTCACGGCCGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTTCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTA
+
+1C-A+EHB4(7$:94%"HFH%H.G:,;,01&6"*-4F+'(&E-<,':?$/F7=-85)?=:189H<A.<;48@C9/%/79-!+E4D2<$8+G481;A,9@>885%5B%25>,GA3D48D81@=H@F7%5/#4$;%$"=';C:?"22!!8(;$.3&$4:C4G,(*3)$.=!E+C.+1(&+;A80@6=;<46D6-!HDFH88@:H<1D"82/=5%!E!C>H;/8#,E425.<%47%8B#%#+9A2(#B(H:1H1405)@)?1=+?+"E0)4?B%>D)6<H#569@AF4*"6>,&(8!A#8&43A&%'%*9G3".,9";=?-85*:+B@.B89#&$&'#&$>.;-".+(3-B5,,5G*)!)4C@=5"''C%C7!<??(3:=A?BF6<AF6E6:7-/%4(1"E73A.@(C4&5H$?AFG<8*-24;F59C2/0;@2*'//%+;B=+C2*65?=C>/BC
@r5357
CTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACNACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGNCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTNCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTCGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAANATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGNTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGACGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGT
+
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
@r5358
GGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTNTGAACTTCTGAAG
+
(+!""%("%"$*&'($'*(#')(("!'*"#')%)$+&$(&)+)&)'!&#!&)#"($%&%*$"*$**%%("&++$(+'"!++&$+!"('(&#$&%%(+$$*%'!+!*#&'+)"
@r5359
ATACGTGGTNTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTT
+
/)%0(6C(A.6'A32)=$&8*0#&A!E="'4HD!2D7!2$!%8'9-<F1<0./1=D>"H#1:"CA?A@%:.A=$.A>0D,+A:AC2$6'F8$@>3A-5#@.38#6B0F&+7:(9,2'D6G$E43%=+.B;1.0DC@9(<?).@434#7%"#74E*D?%&7"(&%&
@r5360
ACAAATCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATAATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTCTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCT
+
267<+6C2F6&!*BB<A">A6(6*40.1G"5?/G#BF74:D2E8>,A=;0*!G$9>?%,@"*;1*(D.433$B-7:B)FD'</?5&<+A25H5@#(01,.:H-*?9@;7G7(6@60+69.&?:C2C0*>!)D&5<'F!C>7;9:E,30>:3&9>"@2>!BA+67A;+0#%7#$&E-)!D*+)##2H/C9:5'51AE8'82=/HF2E'"-6;?(#@*9'(0.,BG##32$11,97@$>$'&59DD04*&<*--4(&=;=23'#(1&:H',68#D#8=;)%$EA&#6:.50B0;#)'AF'6D#7'D.),6#HH#2@<G%6&;;&1.1A,<6E5)?*,>/B#:3E*+-+<,,D'B&+'.!<F"G)<(*$E)1E>/C,GB0+,!4**G'62B2<7??5!>++&5
@r5361
CNGAAGCCACCGCATCTCGTGCTGAAGTGGCGCCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGNGGCTGATTGTTGTGACGCTGCAGCATTCGATTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCNGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGGCTGTCCGGCGNANGTGCTGGCGGCGCGTGC
+
'%)'!*$('+*&"%'*$*+(+!#++*&''+')&%!#(*"($'($*(+(+#$$'$)%*+($)*%)%*((%+&#(('#&#&%(%#&&"%#&*$&"%"%&'%"!+'#()(%$*'&(+&&)!)"+%$"&*+#'"('%&'!&&$+$"#)!#*"(%&#$'##*'!$')$#!#*"##+%&"'&"#$(*"&)')#"#%+*&"%&*&*"'(*!*&)%***&*+(+"$$*(((%"&"&%!#"$%"($%)'&"+&##)*"!!+%)$$+#$&!!*)#$('%"#(''
@r5362
NGCNGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACNGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCG
+
#&"+#*%)!*'!#$"%'')&'+(*%$)*")&++%($)"!&++$&#'*'!('!'!#(%!&'%)*)$$)%%###%*#'")'"!((&+&+'***)!+$&)!$'#+*"*($!*#"'"$
@r5363
CATCAGTTCACCCCCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACNATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCT
+
2D(FH9-&7?"G-G=."20<>"'F(#'85'H45F$.3&)6H+(,D#1)*G"E(&(7*DCG&&(B;>55?3*9CH7)+<09:3'=69#$-A%,!.5=$2G>7:+;#0:C9E>/'.:8C<@+?7>1F+6+CC/73$HH-H%.'#6B:<+(%0A27@:;H-HH83'!F.$0%(8(?43!/-("3,#;>(3+&=(0,$$##-/8
@r5364
NTANCTACTGNNANANTTCGCATACCAGGAAGGGCGCTGGGAANCACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTG
+
%'%)'#$(")&"%$))((+$+)&*!+*"+((&!!(&")+!#*('$$'#++$+$%'+"('#!'&**')#+$"'#*#(!($+"&("%&&'!+"'&%"'##'')"%
@r5365
TGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAA
+
6D?D1/6'4/.8+C%'16%!G'%<:;;44D8A1+G9.,G&C='&D(=,=!EF(E2A!6%87/'+!22>.H.$!82=EA<G;$)$1F<C,
@r5366
TTTATCTATTAATGAATAAGTGCTCACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCNCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATNCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTCCAATAACACTA
+
E1A-6G@,*E@AH6*/06!>=E*@(:&9@:3'!/)3@&59@'H-9E(?GH8*(95?+B065C'!;5D?54@%@D$/G)AF*?C>//@%93-C9F;21&0*EAH4@@@19?,D?"E*-87@/3,93A1,="==E%6>:FFA?35.B04$4'@BEH?0-C"2'H(-=)+EC.:>1+$+8":C6C,%5$D99/0@;0>(*=!A4/17=,
@r5367
GTTCGATGCTCCATTNCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGACCAGTCAGGTGCGGTGATACGTNNTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGNGCGTGCGCGTTGANGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGAT
+
@-="$<%5F466'$57HA-332B7"?8/%-A-3#6%5A"G28=;#5&%9232-G%(E5>&E.80AF9E:),"!,03;,H0=%7:-BG:E0.)/0)$":/<?$.-7?6?,7B30;6D:E=1+*43F")BB&<!'#)F%8$8CD+!?E+0<B*F!==BE8-672,<6"0F3*B=!"6(?+>*'27!B>58<7-=9:8F"7(C+>30E?-E5!:FH8/1-E,>#/G-B##3!D9<?C7%""D:5A>6+'(=8+1$;642#@$7.3D)24H
@r5368
AGAAACCAGCAATTCATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCNTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGNTGGGAGTAAGCGTATTGGTAACTGGAAAGCNACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTACTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGNTAATCGANCAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAG
+
+!!+.<"'"$9G5/=.&?97@D/BE2D#=>%74B4'&#5@$0F,H??),D+"G:AH.48A&$>D!'H*=A!@6?,9971,G)CGF((;,AB<9H443",2.'++2"F:$!0"0B*&A97G3@C4/(-3>EF762;$74"A,>?#<@F(?+A%9?73.*'A+74A##3!83)-(0.3'%.$E5>($!&$1C60;$;"=8!?"-$%:43(A(?C43=-72;-G,:"&*5/<A"C@7+'>5;-.EH<1'26*C1("1:D'@30<@D.2=!#%(:')FDF!&(,7G)!GC>@(46F4)F)%)0.>;19+>/"5#$.0=-:5&'))C*+.0EF*A'+@-7'6H,H5CG/067163$HC:>C<@.4B,(<H
@r5369
CACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGNACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGA
+
';*:<?!5CH>;(@@4;E*7$8C+D%B)C*$5,A9=%EAH$6?-;B%1/8,::E&)!=(442?$.;?$<-"'FEDC)".5CA/)#(+:F,-;%613+"?!;E59;('78$@9,666G):#G>4%8
@r5370
ACANTNAGTTTNNTACAAATGNNANTTTNTTNTNGAGNNATATNAAAAATTTAGTNAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAANCATCTATCATTAAATCAGAAAGACGATGGGTCGCTAATANGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCAT
+
(')$$('*("')!()%&)'"*(&)&#%)!)("&"%%%!$!'%%%'&(!*!+(**!"$")$"$')%+'!(!))#$&$'"'")!))')+(+++**#+)+)+!&&""(+)!++)#**(&&$+'"#*&&'(%)#)&!)**&''*!%&"(%+'$+%#!"'&()#)!&*&&*(*)'$#*"+$#%&'$+$(%!&!+$!'#%(+'$+$*'(*'*#(%#'"**
@r5371
AGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTNCTCAGTNAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCNAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATCCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACCAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGNCCTGCTNATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGC
+
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
@r5372
GGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCNTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGNGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTGCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCG
+
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
@r5373
TTTTGCCGCCCNGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCT
+
/3!F4(B;><:=)4C&,5(48A<3G!98#@FB@9&B5)@2@%?EF#!/0+$4:26F@@!',3)?+CD5*3D7G3'G#(@<?'@!%E3;H:==7E;3%*,98&&%''#074(.(69'$@)F';<AG-C0D41B+/5#E1!;>&G97'C.@A%-7&%&2))+)*%>(6D4.!<9C"HB@3D%54<#+&>&1=0:<C7)+=AG:1$:5<>+HC'<2!@&9E/;!?B62A!9,5;6C".9%5'&*;A2EG8E=1C3FC"=7?"/63+#"=(8&>+:!!E%-9/306,H/G?C(H*.1<&!F,@)<>+G!43(8DD?=8<@%="26@
@r5374
AGAGGTAGTTTTTTCATTGTACTTTACCTTCATCNCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTA
+
/%<61:;E>'BG3395638=9(2D%,)6'E*8%&.C..$@>">=G88@G4=2)E/$!.1?A)8'&5D@+0#GAAHHC<!&3.=E/<B#@8BH,=6&(%?(-"%F4:1F".+3+98)!@#?1*-5EB$+#:@:G#&;@798=3.BBF")#,!9GD0-8A%B:7.40H1H&."AB@F?<:>0"H#H#<%@G92%HD/;EH482,@GF)<FD;"@9>@8G#,;2!,5A%H69.+43;0+=B<D;BG&E!F4)=14'6$C%##B9;C&6C(5'?%%G.F-=DGE<)1+D4B/A%,2A6HF>'$;6:#EC@
@r5375
GCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTAAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCT
+
>'2949'8*C82?E0##0C#;F50"=C0922$?:6@6!&H>FD<48G1A464:<!/%:E.HD:E46B*+8AA@8549<!6=3)3)/)H&
@r5376
AGAATCTCTTTGCACTTATCAAGTGTTTCCTTCATTGATATTCCGAGANCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTNCTNGACATAAAGANATCCATCTACGATATCAGACCACTTCATTTCNCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCGAGTCTGANCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGNTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTANTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACNCCGCCTTGCCCTCNTNTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCANGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCNGGCCAGGATTT
+
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
@r5377
CAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGNCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGNCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACNTAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGNCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACNGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTNCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGC
+
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
@r5378
GTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCANTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTAATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGGGCGCGCATAAAATACCTCTGNGCCGGATNAAAGTGGTTCGCGACGAGTAGATGCAATTATGG
+
6/?()9!4<:&#97A#(!0.@E>F!G9B2F>B8HGG!(;D4;!B286<A*%G&1@F*B66(C:)2@5#6&2+G-=E?=2#*A-.EC:2:!GE6;:&E76FBG+8-B',')!;E1A2D$&!:%GB6!D;,A&'?5E+<F',9&<:H/B",G",))F3:*AE4!.0D7#1>D,,$0=&-&HB-/9H;%)B<F3AC?<(','F4"@ECA=,;?&E+29F$2&%9A8<'0HE,1>5#9/@F"E=+-0*(;33%"B9C4C426-)F/65AEBD*1H:0,H'"'?A"-8<+CH)G.*8ECD"*
@r5379
TCCNACTTTCGNGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCANAGCTATTTCAGGAGTTCAGCCATTAACGCTTATT
+
"#&%&%*)*)!(+"*!)'*"!&&"*"*$)%&&#)$++"$'+*)+"%#())'*$&)))$*!#'!#+"$)+'&$#*"+()#&"+&%!)%!
@r5380
TGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTNACTACGATTGGTTTGGTTNGGTCTGGGATTTNCTGTACTGCNTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCNGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCNGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAAC
+
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
@r5381
GNATTANCNNCTNTGNCATTGTGTCCGCATCCTCAAGCGCGACAGNTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCACTTCTGCCGCGCNTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCNCTCCCCGCCGCCGCTGTTTTTGNGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGNCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCA
+
*'#%(&!)#"(%'#$!(%&+#$%&+#!%!*+'((%)(&#$&&$*&'&$)%(+&(*!#%+!!#'++&(&&#$$+$+(+%)%%(''+))%!$)*%)(+%#*&!'($+&'+'&##$!(#(%$('$+"#*$#('%$("(#!!#&)%)+))($!*(!(%(!"+"*$")!!#%$*+&"+##$$$(%%(%*'(%#*#"!"%($&!$'%%"&#(#%($")#$%*$&%$*&&'+!!&&"(#*%+*(+$*!(!'"+&#)%(%#"*"!#)+)%&$)'&"+$"+$*%&&#'()#$'$"('%!#'%%#!*!%%&##)'(&*+#')#+%%$
@r5382
TACCATCACCGTGTATNAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGGGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGACTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGC
+
'"!%&(*+'*(!&&"+!*!$+&+(+$+(+"()#!*($'(%+#$&'%+%(+&)!%("'#'#(+"++$"(((*!!+'!)(&#!*$*$!&#$!()%%#+%(%#$"")*")$$#$!&$('&(+'+'#'(*%#)%*(!+&!&'"!"*&!$!''*!$*&&""*%+*")!$)(!"(")&!"%+"%!&'+"%**(%'%*%+$**!"")!$+*'(!
@r5383
GGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCNACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGNCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCGGCATCATCGCTCGCCCGACCGACNGCCTCCACGAATGCCGATTTGCCAACGGTGTTCNCACTGCGGATATANAAGTAATAATCATGGCCCGGTTTGANATTGATACTTGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTA
+
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
@r5384
GGCNAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTNCCGGGACGTATCATGC
+
!*(+*%%+*'%%+!%)$!""+#&*&'&'+&"*'**"&'#)$&*($("#&'##%"#(!!+()(*"('*%$"!
@r5385
GCTGGTTATCTGCATCATCGTCTCCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGGAGCTGGCGAACGCGGCAATTACTGACANGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGGGTGATGATGTTGCCGCTGGTCATCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCNTGGATAAC
+
+!'#$%+$(!#&+#&)++"$((!!+%$"!#$$"*+)*!)#(+'"++$#"$$$(*)%##''$(%"&!$()))&++&(+*(+(&(%*+$*%$*#'&%#&$#&%!*%%'''+*%("*%*'!$"($!'""!!'+"#'!%(')+(#)"'"&#(!*$%!$+$+%+*&((&"'"#!*(&%+)"!++)&!($$'"%&)!**(*&+%*%(*!&("*(('*&("*""'!)'%!+$#*'*%'#!%+'+*"')!'$$&!)$%(&%#*$"&"$%%*'"!(!''%+%'&%'"%+'!&+!#%'$!&''+*##!#*)#"!($#*!%
@r5386
CACCGGCAGCACGGCGATCCCGTTCATGACCTGATAACTGCGGGCCTGTCGTG
+
(52F:5H53*9+%'F=9)/4:(&D%6<A7D,;9:8)@@A'+6=8H<:@E)AG=
@r5387
GAGATGGGTAAGCACAACCAAAAAAGCNAGTGATTCTGCATTCTGGNTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCNAACTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGNCTGTTGAGCCAGGTGATTTCTTCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTAAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGNTCGGCAAGGTGNTCTGGTCGGCGCATAGCTGATAACAATTGANCAAGAATCTTCATCGAATTNGGGGAATTTTCACTCCCCTCAGAACATAACATNGTAAATGGATTGAATTTTG
+
'#(')(+(%&')(&$%*'&((+&')*%*(%#&!*##!)"&*'#'"&!'%#((!#++%"$+$)+#(#*!)#(#!+($!"&)#!'%!'%%!!#"#+&"#($$(*'*#***"#$)$!&!*')"'"&&''*"+!)"')+$(%*!(!*'&$*"(&(+**!)&*%($&*$('$!#+!&*(+#'$''++$)!"'))*&$&(!%"('**"$#+!')(+%$&+*!%!'&!)%'$)"+%*$*%$*(#$'+'$$%&(#()(+'#%"(""'+!&#!*'%&($$*)#'!$$##*#'*)"!(%$$)#'*&%&)"$"$$'$#*"$$!("!+)##&$#(+!$%&&')'!"*!&+(&$*)&*#$!(%!!')!(')*$!*''*'(*+$*"%#(*'+(##$%%&$*+"%"$%$!*!+#''*(!((*%*&+&'$!'"#+"$("('$+'!!(%$$""')*(
@r5388
TGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCNTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAATGTCC
+
5>&,4/.B<4;A,G0G$G10%E74%,H/F8"=H"=(F#">D=E8)=:H;'0(F1F)G=7,=D)E$E8.#":F!4=#*5%+)/8-4.0,A6'AAAH(*2(G=4AA<-H*1B"B?.<<$)!+(C7*G9#"'$
@r5389
AAGCGTTATTGGTATGCGGTAAAACCGCTCTCAGGCGGCCTTGATAGTCATATCATCTNAATCAAATATTCCTGATNTATAGATATCGGTAATTCTTATTCCTTCGCTACCANCCATTGGAGGCCATCCNTCCATCATTCCAGTCGAACTCACACACAACACCAGATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCCGGTGAAGTTTTTCCTCTGTCATTACGTCATGCTCGATTTCAATTTCTATTGATNCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACANCTGTTCATATCCTCACNGATAAAAAATCGCCCTCACACTGGAGGGNAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCCTGTAGTCACTCGTTGGAATGAACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATTATTGCCGTCGTTCGTATTGCCNATTTATCGACATATTTCCCATCTTCCATTACAGGAA
+
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
@r5390
TACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATGAGGATCATATCGTCGGGTCTTTTTTCCGGCTCTGTCATCG
+
2@BG.D5#."FG2C,0C*:C>*E#<B+#02FA4($=!F0D>.-?<39<1:@8G&7($.5"/F36?1-(G#+;.64*7)1(9B
@r5391
AAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTG
+
9$5*F!F*)!1,/BGF8$4<D40AFF+''F5>4$C%#<@;D;C$4#6*4)H5B>"A&G7(
@r5392
ACCTACCAAACAATGCCCCCCTGCNAANAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATAAATACCNCTGGCGGTGNTACTGAGNATATCAGCAGGACGCACTGCCCACCATGA
+
:D5++2+0/3!10C+5<93324<F"+"8?>6-9&$#1/B4$BE8-84DG85;@59H?*,C>-,4E5.>'/%.6H5'?@)*"A70.?9G0'E@?/F+:&5@,D94-H:6@%#9-5G88@:'DCF7D4F)+C2,*8;"6!94#<0D:(-;C'H3
@r5393
NGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGGTGCACGGAGTTCAGT
+
"<50F6;>;G1?&/)-D)9H/&0/:'=%4-59/1.A9>:@3/?&CB/7,:,6H8&E,49E=)D,?D6)#;
@r5394
GTNNCCAATTANTAGCACGAGTACGGTGNAAACGATACTTGCCCTCTCTGTACAAAANATATAGATGATTAAACCCAATATTACATAACAAGCCTCGCACTCGCGGAGATTTNTTTTATCTGAACNCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGNGGAGAACATNAACGAATGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGC
+
($%(%#&'$&(!$(#&*+&%$*%'(!)#&)#$'&'**+"&"$&("!%#%!!"()'!)%%!"'))*+&#""!$)$%##'*)%#%$)&("$(&%+#!&"&'"(#$*)&'+&)#+#'+$((&%&++#*('(%&*)+'(*+!%!+&"*"((#$!!(!"$!%&%*)!+!'#+'$#+#&""#"!#"(++$)*!(!"*!*%*"%!%$)+)('$"'"$$(!))+$(!"#(&#"++)!&$!)!&$(&+((!*&&$*")*%$*!)"$()!!&+'"&!+#+*!#)&$"")%+'++)($*#"'!*(*%!*%($$%%&))&&#&%+**)*)$+*
@r5395
GCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGG
+
$G90<<("6$%1$30,2;1':C**H(3@G7?;$D'0!#*$82H?*BH#</1"C0'!3#!=><6%<(#-#&38!)!A<3(?;1'?97=/".-7$(6%$@04-?HGB6G@#%E4(5@E3-1>'47+#96=2A
@r5396
GGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGAC
+
1;;EF?6B(;E+!6;G$&2?-,9-307@B&5A(GB4-1-%B!G)
@r5397
AGGAGGGATTGCAGCGTGNTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACG
+
/A@87'#C%21:=F,8@(:!CF0B/$8!/#-9>)2>';+E70*$@5@-%:)EDF#D'A9!0&A#H;!(5!0<&,"-7"<</&965@>*(?+,)"F!C":?@,A"7-B-D.1H)1$9F7E&'#=5F2#><@1D432%20=((-/,>-.F>(9:+**8;1&35*-E.@#=
@r5398
CTTTTTCCATGTCGTCTGCCAGTTCTGCCTCCTTCTCTTCACGGGCGANCTGCTGGTAGTGACGCGCCCAGCTCTCAGCCTCAAGACGANCCTGAATGTAATAAGCGTTAATGTCTGAACTCCTGAAATAGCTGTGAAAATATCGCC
+
,$E/<>(=.$8'(8#1-)E/+.;.H?%B3'=&;+B?;EB.B&(%&'E5=;=H6038+1F=#E&8++G@F9"8A@6;4C<'#A"-0112+376@'.(A9&&;3+5()?/'/'%,.EG:+=2>G.-#;AA&$'7&3H,4+%A8<HGD,$
@r5399
TCCGGCGTGGAGGTGGACAANGTCGCTGAAGCATTCGGGCTGACCACAGACCCGACGTCGGGNCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTG
+
(+!('*'#!("$"&)**&!%)%+*+''""!"+*!')#**(*'&$#%*((*%%+##*'*)''&#++(%#(#)(%#)%$)(+%+)"%!%"*+&%$++%##(+)+(+**+(#+#$*(*"'&*$!"'('%+&+
@r5400
GCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCATTTGGGATTCTTGACTCGATAA
+
%F"$<7,16CB*E-4#1+C6!39;"2,0:1+E6)G!,%5@1BH@8G@;!3DF"G7,;5H75C@3,4;:<)?D#;C**22CB<=++=;629)<%22*/(&9.A<D('=DH@>#D,'H&DA$1E!G.7<@$1E-(%1($>,H!5
@r5401
TAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTNGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCAAACCGAATCCGGCTT
+
E8E/'6>#<B9:9*G"-7-#-!./'4;,5;%)?2!#,2C*6&C:/2=!:-A&8<>E(8G=,/44?.&=H!%;!,75+!,A1!5;;2>7+9H''$9C)%C!?-@$9D%-9?@*>)E-D(<)&!4HB;2*D6*>&6H!8F1,E6C7AG;:D?<13'!!B<15(!$&'/0;70'0+F?3D3(//
@r5402
CTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGNTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCGGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCNCGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATTTCCATTTCTGCGGCACCCAGCCAGGATACCCGTCCTCGCTGACGNAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTNGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAAGTGGTATCCCAGGTAGCCTGAACGAANAGATCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGNTCAACGTNAATGCAGCAGCAGTCATCCTCGGCANACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGAACCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGNCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGC
+
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
@r5403
CCGTTCNCCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACNAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGGCGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGA
+
3/=8GE1/1HH>586?C(*2/!/?*B7:.5:7D!7C+982B<="C.+-&68,*E;&@@%G9%77HB=H1HG=$H<)?9)7/*9"&$G"8@#9(-%;..(8!271""%6E5C$G30"5=.F$*B7D?.?D6)8?'*B$0D'.>*A80
@r5404
NACCCANTATTNNCAAGGAGNTGCTGGATNAANACGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGATTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACNCGGCAAACGGGAATGAAAC
+
$(%'"#$"$&#$!))($%**!*($&(&(&$*'!"+%"(+)'$+**!'*'!('""&#$#&()%*!!)#!*"#&!&*!+*%)+&#)$+!*)*)%+"'#+(#+%%$*%)'!'++!*%)((%#!#'##+'$+))%)#%++$)+&!$(&#$')(&"'$!#&'!"#""'$('&#&(#''(""(%)(+*()$+!('+#&#*%$%)"#(%)'*!#&*'"!%)!&"#+'#"()+&&'*'++&%*#$"*'+'!&&)(+%%%*()+(""$&&+%!&&&%
@r5405
ATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGTGTAACAANGTGCGGTCCTGCTGGCATTCTGGAGGGCAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTT
+
)((+)+++'&+%!'*)&*%$(#&)*%)"''#*+)+*')$$)%+*""!&((%'!++*#)#+)*#&)))%!$'"!&((%##+%***+%()+#*(&#%&+#!(+$)')'$"(*#(!#(!((+#)))*%('&(!*))&%+""*$!&&($#%#+($(&)+%)%(*"&)*$#!$&%&&($'$((&#)&(%((!)#(!((!**&%%'($*%#
@r5406
NNGTGAACTTCCGATAGTGCGGGTGGTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACNATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGACCGGACATTACAAACGTCCTTCTCGGTGCATGCCGCTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTANCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTNTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTNGTCTTCCTGCC
+
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
@r5407
NCCTTTGNGTTCAAGGCCGTTGCCGTCACCGCATAAACCATCGGGAGAGCAGGC
+
()#'*)#$+"%"#""%'#"#+'+'*(!&!+'!'!#&+%"%&(!")"%#$&!"$&
@r5408
CAACTACCCAAATATTTCGGATTTGCTGCCATCAATTTTTTCGT
+
1<35*&:,-82+;E81:18GH7&B8)$E02-5C<#2($)51#**
@r5409
CCGGACCCGTTTTGCTCAAAAGNGATGTTAATTTGTTCAATCATTTGGTTAGGACAGCTGATGTTGC
+
E&F9$CF=9"&8E7%;'#5"=2CDG63.C)!1!<A'=F*.'36>;4/:;B87%3;3&:4;%&9/G48
@r5410
TCATTTCTAAATATGAAGAGTTAAGACGTAATGANCCACAGATTCAAGTGGACGATGATAAATTNACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGTTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGCTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCNCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCNACGGTCAAGAGAAGCAATAAATATTATC
+
::1=AGEB!(;9.0)9=$C,;+B?=C(-A+-HC358)91*3C:)=B/:+C5)1=%.G55)8,0'51?4?)2F<.>*9HD*65EH/?,-%H=%H*<=E'696/@F@7/'=.":A67@6%B*)*!(',BDC"),$74$+>#'%-B;6)A9/B$.F/4C95A=&98?5$;8)2:;56F3*<'(3?DH03G;"3EH$3*B'8DF<&:,#4!:@2HD('8?(,*A5>3F=5?81,)DG/?8;,E@<D2HH'.FA=?>D=@0#=/D+-8GC(7EF*/&4H<E((>8'=7#2(?7#"FEG$#A@4&/4(9"(",A8/?E,6=EG/9=1&?7,!.)(2%@G:5+D?E)@E!/2-#3!:-E,F8B'4'C2A7>4F3%1/)
@r5411
TGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCNATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATGCGCTTATGCGGATGATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCANCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCA
+
C?+-7C*C4/'<%D<#C3,'&09,<6H;:G/88A)AC@E6FA6@DH=/E5<,:!,=8"./6G$4939--&,38/..D@E?'48)6>!:07E"GC!)&>"1:51=GG;!+"&2%,#GD(7)0F2B!>7/3+&$"@D/.,';A9$6=69H40#-;9;5)GEA6;1!G,A?,5*7&!+H'B0D?*#(8@*/<98H<D2$0AC6'"%(/EC141G%-3-,B&>'E-)91&A#:3**"$9&44E=&/+7')18!+<#1*=%5>A16,<A;)A4(D16(,+FC&!690=6((E4&8>,!>4<$63*26<;B:E*%&E,>.91(F2#(6A@0!/>%(-)1-<*2,4#(5?4"37F-EH5:)D%>"5;0'E&.><;;C0>#D=97:1A7:!=,%A'&65:46?&1-@9
@r5412
GCTTGNCNNCATCCGCGATATCGCAGTCGGCGTCACAGGTCGCCCGTGAGACAAAGGTACGCCNGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATNGCTTATATCTGGCGCTGGCAATAGCTGATAANCGATGNACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAA
+
*!#)!!'+!$&&$''#$$&((*!*+%!!$)!*!+!&#)'&*+*#)&##"%"(*'((%"''("!()&!(&#$(*$("+#+*'((%))!+$*&#''"#&#)#"'!#+**"*&%%)+#$)&+'&))()%!!*)#&"#!++*!%()"*)%$!+"#*"#$!(#*+!&%'+!)&)$)+$)"(%%)+)"$"+*(&)"$)'&#$
@r5413
AATGAAAAGTGATATACTGGAATGTTTTAAANGGCAGGTGGGCAAAGTTAAGGATTAATTATTAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATCGTAATAATTCCTTNCGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATNCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTNGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGNGGCTACATGATACCCACTATCGCCNTCGGCATTGCCTCTGCATCGTTCATNCATATATGCATCCTTGTTTTCCAANTATATAATTTNACCAGAGAACNAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGNCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTATGGCGGTGTTGACATANATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCNAAGCAGAAGGCTTTG
+
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
@r5414
CAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCA
+
(=1H:E@'=D&@5>,G9(4'>G4?/8/-;=;H?$EH3E17'*$<C5F2;2"13-78/.0E3G.!HAF$-8%G9&5$?9#?+H&*A&BA?5+H#$E$,'26BD".@;@6A#4$G?H3@C)!&5&+$#'.((9--/
@r5415
CATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACTGGGCGTACCGCCTGCCGTTAANCGTCGCCGCTG
+
4A/-AH&AH+6?C+2=3E'3'"#*5!9==F=.0C1=E0@?8E@B"7)1$:?#..1G!A?-+7DHGA$FE9AB)#2,DE6E:!C"?2!BE9,%+'+)77D&#>0=*8>*
@r5416
NNNTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCNCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATNAGCC
+
&"!G,3B!&@88$$!==%#''D?&=8%2H06;48CH>G;;,#1!&2)".;'>+.+DC8<A=8,6+<-7C4BCA"'%*/G#@0:!:7%5&/;&C*!#<:?'*D.99:.:<H%14184E7(-7?4:E.54<>73D"(&B$+A;9,<?.1(!<C%)H';+/?*9F::;=#1??*3D#843'#2C5;H%:(>*<$<!&8(-&)$0F89)6@BE:D8CE7$)&*+
@r5417
TCTGTCTTTGATGAGCATGGTGAAAAATGCGNTATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCT
+
(*%#'*((+!!)$+!!&$%'$!$%"!$')&+$""+!#'&%**+"%((!'+'&##!((#&)')%'$++%"#+&(#)'%"!""!)!&)+)##'$"**+#'+"+)"$#(($*$#*!+#((*'"(+'+(&($(%#$)"$"
@r5418
TGTTGCTCAGTTGCAGCGNTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTT
+
H<<&99,-,<?>&B$>!0=7F!(7%$;;>HG.68A<+F>!/!&>F<%.47%@;"'C;:<>?5.3.F-09A4A1,2,
@r5419
ATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCAAGACCGGTGAAGCCTTCGATTCGGTTGNGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGANGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTNCTGCCATCCACCCATTTGTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCNGTCAGATGAAAAATATCCGGGTTATTCGGGAAGTGAACNGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGAT
+
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
@r5420
CTCACATGNTNCTGGTNNACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGA
+
(#'$#(')#"!$$$&&'"$%%)!$+%*!#"!)*#)$"+)&'"+$'&"#)"$"!)$$"#+*'"'+'*'+!&#$!%(&&$()+%$&(*))"($!"*)(!!)&#(#+!%$*
@r5421
CATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACG
+
@"E%*'33>B9"(E;/A.B(*/?(*F#/97A-8!;/BB=-4%F>4HEF<F.
@r5422
TCCTACTTCCACACCCTGCTTGNTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCA
+
;!+G%9)4/9-/64<"GE"(/4-/#4'53,=<.+8+"05(8+9-9F>9@E9BCH"!62.@6#>!=81@3;F9);/=+)G820?+E*0H4@7B;/:'74E#
@r5423
ACCTGCACGCCGACCAGTGCCGTGTTCGGGAAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCT
+
/".%?!H56>=E8*FAG,20<H>=8)&5HF4'G6=6$&1$36C)2;8B"*6>%"+>G.,19,=H<.6"5);.?G*%A.!@88):H
@r5424
ATCAATATCAACCTGGTGGTGAGCAATGGTTNCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCANCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCANAGCGATTCAAACAGGTGCNGGGGCAGGCCTTTTTCCATGT
+
+#(#*$!+%"$$"*'*!'')#'%'+)!&!%!'"%('!&$#)'#*+*))*%(*'*#(*+'%"*)(%+!"#(%()"&!#+''&"''(*'&'$&$#$*"$#!$)&'(#+&#+'!#'$*)!*!$)(&#('*+*!&"$%($()+&("&()($(&#"&"!''#($#*$%(&!#!!)"""'#'+)')!'$"+
@r5425
GCCCGCGCAGANGATAATTACGGCTCACCTGCTGGCTGCCNANCTGCTCCGAGTCCGCCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCNGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAATGGGCGCGGCGGCNGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTAGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCANCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGA
+
05(.AG/FE3405GDH:50DB.*>E40*:/0>&G09:%*'D&H<43%?)$6-0#78H6+H-5*(*4(@ED('1"+C1%*.H?4(E<#HA3,=<-C8+"5,)AG8D9@+2$B>D',.?#-CD9=<2470"<B&/'FF/HD/>>,!)(8$E@F2>+$H-E41506870CE'>6@!%!!%)@(=@86B0G=D;H?D5!H)*%<&-C04EBF=2H4?3#*5'&8&-),F47@?@&-2)7!2"E9?;$AF/1G(262>,83G/E",)"&52)1%($,EH>>75,;AHC(&5BC=07F$0@0;H-=/*731)+4<$D50<384$B>E6>BH+.>&7,*:D!$:C;<2F1E>1*1$0C4B('.?&.&/)->/?*<C'64=/*@6$?:>!?+131C(4B3$,CC+EF%D7@%8:.*/(-B!,7+9E-+'H953/..5@)$G#>(1G33*9+9A3"*!!8D7C3AD1.*&7,(9/>,5$?(BD'
@r5426
GATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTNTATTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAANTCATTACCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTANGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGNGAGGTGTTTTTANTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTNTTAAAAGCGATGATAATGAACAGNGNTGAAGGTAAANTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATTAATGCTCGGAAGGTATGATGCAGATAANAGTTAGAAATAATTTCATTACTCACTTCC
+
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
@r5427
NCCATGCGCTGTATGCCGGTNTGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTNGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCNACAGCTTGAGCGCCCTGANGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAATATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTNATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCTCCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGNTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACNGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGA
+
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
@r5428
AACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCNAAACTCAAATCAACAGGCGCCGGACGCTACNAGCTGCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTACAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGTAATCGACCGTNGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGT
+
*6>3(%"9)'H$B8E((#2#9"B2=1"@&A&">*-5!0ECGD"?%!#6+C@<-49.?=0*&@2/B%>C:?-A&!="""(E$"%12-B1-D3&7<#:8A$96,<8/-)<*!@C@.-:@C!$E4$/<;2@.;!-1%B4%?-#87?$'%@E<%7(<,6HEH>=E2.)!H'!9==A?);9.35A"3+D1EF90B0-"16??;-+%6D2A&:&-2&<1$/+10)D2B4A%4C>,/!359G'6!0%>!!E1)H,DA=,,94!&8"<:"!E65+8CH@B3+!G;%%4#DD/E"B!F)=H4A/H!25A)=8).$1+/:GF?F*+-8D<<!5'F0G@?**+>8<<=)535BHGB0"3;(<:6@@E/0$7@,/C6"6C,D0C7F%(FB*'A+%!?4H-C95AB'''?!%)8:-";/:)-?08#7?BC3=<=433*&98A-"0B@);6.7
@r5429
NACNNNNCTNTCNNNCCNNNNTNNNCCATNATTTCANCGATNNNNGCNNANGNCNNNTNANAATTNANTTGCNCACCNNNNNNCNCATGCNNNGTCNNNNANGTNTCNGNNNNGANGNCTTNNNN
+
""!!""!$#"!"#!$$$###""!#$#""""$##$"!"$#$##!""!###"!#""!$!!"$"#"!#"$$"##"!#$$#"!"!"!$#$$!"""$$"!"!!!""$"$"$##$!$$#!#"$"$!""#""
@r5430
GCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCTGCAGANTGGAGGANTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCACACATTATCTCGCGNGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCCGACGGCCCCCACCATTACCAGCGGCGGCAATNCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCG
+
0+B&H<2#C+*E-7DFF4/(323<(=<6&1:'!%1+A?,"&?/8'F"?3''E2'>$.<&FBB<@)>@0.#!!!>=:7C76H/E:;*3$'7&0(.-8,0>$G,1<D6F>)H?G:(C*!9#>1E*/G:A)C0%#'!FG-;(53<@?=G3F;37>6)B2%"232=6:156>*()*GE+<D!!3"EA28#CB89%!0.1/,B+&*<=<=@D7--=,($<"9+:4A=&4*G!30.5D>D#$!06#'?%24B.@.F<.)>C8B074:2F/3E#3C$:B21F+5F(2%.8/6@?B2,A"*A$>$)&C*.D+>-/A*#!<5;8<+H#FB:'-F>?<:$:"?!(46*3.9&FA>??3<8!$446''"E(/G8#/F$)6H.'*0,3!?4@(;:G41E6/$6&2'20'+,;(@+A8!7->165#9&,91.<'1D@!20?8F>19'95(,$)3<>G?'A0-.:EB,:#"#7:7C@,8=AE//F&C?D
@r5431
GCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTT
+
<;6(8?)='2.D83?'1E!6:;3&80$%C7-&,8"7C30<=8+!=23<GHE2*%#,"$2D%"8**6G&%=&(?0H'#<ABE
@r5432
ACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAG
+
B/;$@#01GH4,A/7:,2@6,"+,4F!#D%7',E&@)6&>G12'22";25>,D+F.!*?/+2H46/E?>G63+,H9?6%9D,;EG>AE"$7?2<D<82.2><3'A/GEH4D13#)+G:8=&"<6.+A3H0EGC*;:4(-=:'$&G%9)%,H1+""EAH$@3?.9-?7<@F<*3#E&3B+HE)EE#H=+:>?<<E+/"F6(3B*5G%,3B8
@r5433
ACCGAAGGTAAAGCGCAGACGGTCGANGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGT
+
F$50G<&HB&&0470B/<3G&=!%8>%)()0*9>7;GB!0*></<&,1.%6B&E)AF?4G34?:FA%900-4G""HF2
@r5434
ANGTTACCAACTACTAAGGTTGTAGGCTGAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTANGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCT
+
E)F1AHH(?)G++G7>'"9:.8:$9@A"6#F=#;(;=:"%-F?&3@7*$""H<:.4">F#%)8DA*A$';'E#1-E19A!89->4$>&63!5$6/+>!G,F<21.2830=-E&9B0B3$-<B;;&B>-,4@9!7#="'&'3A2C4:G>;6/HADC;9;*32;>1@"<?8.='?<D87)EE;;AADA$&).91F.C%&,,BF?1<::+F,"<-4=0H81(3@7#,A6>97B
@r5435
AGGGCTGCATGATAAATGTCGTTNGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGN
+
@"FA,((&9-')'H.:;7&G(D:'!F5,D@&CC;%>C"AG:=$B$5A,,/32=C$;*)'>75'CAG+E3@?9
@r5436
TTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGNAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTNCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGNTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAANTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGT
+
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
@r5437
TGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGC
+
/;0-@4-D&.'()&2'C/G>!396:#+"9@&<D%63?*8B/.H2DB:.3F;36?'%,="8<%;3#%/20,14!)F#%#.F!81F*16=..(+E1(C23;1->7/)0>DC>'B@0+,'+:(6-GC8-2%C>:=C;C0"G:?=/C6;711#$E9AHD9*;D9/"6!&H>5@%>6&>#A8F415%,-)4'?H:(&0D2=!F&=4&5GB<2*=!)=AF+&(F=7CE*(;B#.+41'4,;',>'E(@+&;,;6-&=9?-G@01F">;:!#&*@*B<E<0F:<(>+,87<=.0(%C1"74D1%6@CAB=GC7<E:>8;'B/#=&8)?#$)(FF?%0(1(*@H&;2?2502-0"":8!03,H<C>G<H
@r5438
GAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTANTGCTG
+
;11%=/2A&?%%<E$@E)%4A5#FC8E7-$+D-02:HF26$%@;'FB=#H"%7<D'F55)969.9.C,@2&?@13HC5G*E%'2&1$1B+"3D$.,@(;'.E!*#F%20A4AC;HC02!>>0%C14?!ED<A6%1-%%"+C?!3&3@G"79;85H/0
@r5439
GTTCATGACCTGATAACTGCGGGCCTTTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCACCCGTCAGGCTGCTGATCCCAAGCTGNCCTGCAAGCGCACAAAAGAAAACCCGCGCATTGGCGGNTTCANACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGNCCGG
+
DC0<<4D,"E!$>&B*#+#F((F/!,'*+.D'EE)(2!4/D(G)!=,!H2,4#!01504&=#*3B'96#(9@!C%6)H;H'E=-$E512F5G-F$1F*=@(FB0H"9D4;A<::,&-?5BCB:"C0AA(6,9D->,699F=D-'+%-B=(C;*E'"/<./$B3,/$"*H?&<%+9$>9C*G/#7D-6':B?$8F7,8G)G/."-/;H"?'E6B?3C"";*D;"B'(DA=$870249,78<CE1/(;)!4@E)?,2"@!H,8+97A!(B)*8)"
@r5440
TTTCACGACTTCCCCACANCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTNTGAGCGAGGAGCGGAAGTTAACA
+
F*%G8D/$(@:B73E,GC77#@H:C"2@1"@=(FFA((.3<7,<#&/415-635)B7D.H3)',&-5$H2;DA<80%"2.>0&$;/7
@r5441
GAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTANTCAGTGGTGGTGNTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACG
+
(411%G(D@08&+4:,&?&G&3"<!='9>C1!*/.6@+@;&C?>;#E$G!B-%A%:/;&!;E7@E(-!621$61!'@C+/;8E3-FDF*=3?4G52FBA.'3'G#,5GB::&<;4>A'-+>H8.8;
@r5442
AGGGNGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGAAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACGCTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCG
+
2E1?/+*-2?A8"#&>;&"#?(+>757;/3"H>1>-@2:;=$.*?G0(AE*A</H3-CBB.)C<A+22.%).!9-@F5DD0BA0%F)CA<</*">=2>'0&=,,)B9H66E?58<#'3%(3-6/;%3#58+=:);(<0+/03;2##&7+"G,6#AE.F3DG:'167F8.C&932%&#E&)B)%>!!+D+@
@r5443
TCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATCACTCCATAAGNAAATTGTCATTTAGCATGATACAAT
+
0.8+?G+6DBG);9#:4B;1!808A'>!(,'D27+<(BH1/)9>.99*&"?26FB%+%9-%$D#EG&*@-@C663"46?#,(!/5B>G03E+!F
@r5444
ATTGNCGNANNGATNTGCGCCATNANCGCCTGGTTCATTCNTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGNTGCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGTTATGCTGGCGTGGTCTGAGNGAACTG
+
)&#)!'*!)"#()&!&**'*('&"("*$+!!*+*%$(!'!*'(+%'#(("##'$!'&'*$!$&)(##)*%(%)$%!+&#&"+''*'(%#$$+!#"(#+%#*+%%$(&&*$$$$#(%('!!#*!"%*+'*!$*%')&#*(()$)&+()&%$)%+*+*!*!+"&$$#)(''*&&&)*##"'+'")(&((&$&"#&$+*%(("#!+'%*$&'%%)##$#"*!#$$(%"*(+'!&!$!)"
@r5445
TGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATNTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTNAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATT
+
8/-/)/HHGC..B9DF2"3:8GE=G5*"()A:,E!GFG(:;8+->=E/?>C<$=67A$)@)($B-"+#>-*(4!"""2>8&5E=/8A).&<<5D4E*%/%%0+1'.9+&:4-GE,"F%/.A"<>FGB73*>"%/:$>5D+6ECE((&:D4=729',3'89%'8>%&4'25@1F,%-*DE"H%18H3*6/:$@<4-)'%*-18$!9)*C82?6"4?E9/:!18GD-&50>4F7-#%+6%+C=B#D4#2E.;F$BE+B=!=4!2B,54(A#):$--:4)'7/#&&;E.1E<
@r5446
GGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTTAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGA
+
'<(E56#(;)3'(2"@?/9:8*,E815&98*7%G#(H#(<C245-..4,8D,'A=!D<'+G05!F6&D2)6<062E<@F@E-;@-++66=#*,4A3049BG,%F0'*-4</C"E:;>D.B,"A*!G!B9H.76;:3?:<9:<@)%A+>60;!1,DB0D-BC-(D23H?03
@r5447
TGCTCGAGATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGG
+
66=3H#!'*91/'<%4A(G"8F!)B$F(G18H?&%G530HG@;C%99=H$7"@534*>"B(5"?)HBD3":&3
@r5448
CNNTCCANTNGTCANGNTGATATATGGAAGAACAATTTGAAGAGTGCGAAGAGCATCCTCAGGATGTGATGGAACANTACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGGTGCAATGGATGNAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGANGATGGGAAATATGTCGATAAATGGGCAATNCGANCGACGNCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTNTGGCATAAATAACAGAATAAACACAGCACTGTGTTCNTTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTGCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACGAGATTAATAATTTCTGGTCAGACNCTGAATACCGACTCAANAAACACGGCTCTGTATTAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGNTGATATGACTATCAAGGCCNCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATANGCCATTGCAGGGTGGCCTGTTGCNGGCTGCCCTTCCGAATCTTTACTTGAACGAATCNCCCGTAAATTACGTGACGGATGGAAACGCCTTGTCNACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAANAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAANGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCCGGCGATATTTTCACAGCTATTTCAGGAGTT
+
*"$))('&*"!$$%%$"'$+"'&#(%"$!$((&"$'%&%+##()&&'"%)!%)#&%+"$""(!+"''+&!%($&**(&#!)*&(*!*)##!((%*'$#'+&%#*%'!&*'$(&&)('"")'"&#+'#$(!'(+!))$$$($*++'%""#$$!()+%+*$)%")(""'!!#$!#''(!!*")""#+*!%($%(%"$&%#$!*!$(')*+'#(!(#%$+*$!#(+&&""&'!$!*$%#'!*+%("!"&!%&)*%)!)(!%#)'#%'$$$)+)!(&"!&*)$*&($)#("%%()%"'"&**'%*!'++%"+#*&&(!$%!(!&*!$"%'(*&!&&+(*("(""(!*(()**)''"('!$'&'#*%$)"$)%+$")*((*$(!!&)$*!$#%)##$+++#"$!*+&$&)%&&$(')+)*&'$"'!))*(&)!!''!+&(+)(&))#$#!*#'$!"++#*)$')+#)+&)$&")#"&$$&!%(("'"'%#+%"*&&!*!!#%*(%("++)!#'!)"*)'%%#*%(#+'*)"%)#!+$$!#&%")+&$%#!&"'+))(&+!+(!'!++')'&*&*$'!%"$&&'*%#%%(&(&*'+*&)*""#))(&*&$!"%"%%$$(*+#'*$"%"$('#!'!%+*'+'(&($(*)&$#"(("%%'"!%!$(*%$#!%$''#'+"!$"%')+&++!(*(''%&&$*'&")$&$'&*##()+%''$'*%%%$%!%&$&#%(+*%)%"'$!*"$''%!(*'%)#)%+(%*+#(#*'#*'%&+&(+(&((((+$+'(%)!$!&*(###)(%)'"!"()&%'"#)*+"#+$&&*"%+"##$)(+#)!!!$*)(#**"'%$*)&$!#)"*&!*(''!$*+*&+&+%#'!#((%((++$&%*($*#'#!(("%$#")($+!(!##"#%#("$+)+'*(&"*&!("(+$%"#!%#!+"($%!#*&*'#(("(#&'"*#$)&&##"+#%+$)&%**(&!%!!*&+!""+'*+)&''($%$*#$'&$#+!%')&%(((!*&+'(**"!*)*"'%!"&)%('&#+(("$'&)$!%%$'$&$&"%!*&)%%$+)!&&$"(+#('#(*(')&*&(#'#*"##("#!))"!&!"+(%*+&**(&)"$*$#%$(""!""!)(+('%%+(#"'"%#*(&!&%!**+!&+%"*'"($#'+(*))'&!'#+(*'#%(#!$%#***$#)&))'%*()''"+&*+&)""#*!*'!#!)!(+%"!'&&(&#%)%#*()+'#+!(
@r5449
AAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCTTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCNGATCGCCCTCCCCACGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCNCCAGTTGCGTGAAGCGGTATGTGGTTTC
+
E;)?&:+.G>,!=6C.B?'=:;?"06<-H1)<C4)C,?/4E9,%:.="342?+"(-4'B3/,7(-/H!E(%2>C(E;>F>D)045;@9.B$$'+70@$CD1:>A-;0CG%;E%6B-=F!96(3.!:$#.%C!@2G#1-&DE>75C17H<?9;(7C?80&G@!G>1"=EHF.&2%.-G;D4CCECG
@r5450
NCCCNCAGCGTACCGTTTATCGTACAGTTTTCAGCTNTCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTC
+
!+$&*%+%&''#')!%(##$$###"*+"(%)&)((*(%!'%!%!+"'+")"(#!')")$)*')%&)*$#"*'%%(#+&$'"*!'"$++&("(+"&+'")*)*%*+!''+%$)!')$
@r5451
GCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGG
+
C-F;,;@??=B,7E6!?A2>#B<@'6FB+4<5-*HFG.55CH/C?<<2C'-,4*A*!48092AB15+'F!2CEG2(H$)E!"#/?2$'+<!?(/-#$(+>B<#5;!!B-00BA>,<3&#6@*+)+;A69H'*=6?*3E@706/!4:6,2+-8,!-4/09C74;4D?:084B58%+G-3@%8562C8"'9&#&"#;(2((4HB79<*-
@r5452
NAGGCTGAGCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCNATTATTGTGAGCAATNCACACGCGCTTCCAGCGGAGTATAAANGCCTAAAGTAATAAAATCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAA
+
!5($*B&05H?H(%0"<:7+1-3*8#:+-;D:,/42&)&#%(!.&3127EC9G1+H,"$$-/6!3!(4+/>@CG%5B!&H4!!+31(FF&E(-9>,C-7&3)4.+;25&2:5D+4,()-9B-%6;*79)2?$&<63:E<4<.)>;,#?B=A#C6."6;+:C0/,%)72;:7/?,(72#+9A@-<=/B0##G$3C2:+#>1@%/3%*'*&$/"8H$H(5+@5?-2)>H&EC'DF)C$4!373"$DB*2"B"*3=-.)*":3>&."F
@r5453
ANNAACNAGNANCNANGAATCANNNTNATGNNGTNGCGAGNNCGANNGNATTATTNACAGNNNANTTTGGNNNACAGNCGCTGCTATTTNGNCNGCANAGNTNTNCAAGTCNGTNNAGGCNGNNAGCNNNGNAATNCATNNCNGAATNTNNANANNCTNNNNCTGNANNNNGCCTNNCNAGTNNGAANANANCNGNNNTNNCCNNCNGNNCATTNNNCGNGGTTTNCTNCCCNACNTNNCCACTNCCANNATGTNTNCNNNTGNNANNTTNCNNAANNNATNGNCTCTNANNACCTNGTNNNGNAGNNNTAGNCNNNTTCATANNGAT
+
"""$"!#!#"$$##$"!$$#!"!"!$!"#!""#"!##""""""!"""###$##"##!"#!####"#"$#$#$""#!$$#$!##!$$#!$!#!$"$""""!#$!$"!"!!$$$!"""""#$$!!"$$#!"""!#$"!#$!$""!"###"$!#$!$!"$!#"""$!"#!##$$##$#$""!#####"##""""#"""#""$""!#!##$!"""$!#$"#"#"#$#"$"!$!$$""!!####"#$$#$##$$!$"$"!"#$!$$#"$"$!!#!!$!##"!"#$##"$$#""!$"!$!$"!$#"$"$!#!$!!"#$"$"$"#"!"#$#"$!!
@r5454
ATGGCTCACAGTAANTACGGTGNTGCGGNGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCC
+
02?6<*,A,H?&C'/ABE&1.G=:6CH>2!:B2)9=G.3275C&>?>E,-,3-'.*)5B6CC53<?=/@>=;49E?EA;7>@/F;>E64
@r5455
CAGTCATNNNCGGTATTCGNNCGNNGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAAC
+
"&"#")""!*(&%*)*))"*#**#$)+"$+"*(!+&%""&%*$!)&&'(!&)+)$!)'$)*&#!(&#%+*&(*++(!!)&())(&!$#'*($'#"&"&!#)$&###$$%"*++'$&$)&!%#)
@r5456
CCTTCAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGNTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACNCAATCAACAACTGTNTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGCAGGGCNAGAACGCCAGCGCGGNGNAGCNGGACGTGNACGCGCAGATCACC
+
7)9(/%D=F&'D*D-F#!$9(2+29?6?60?3-"F/,G0='2,01$.91H.H9";"!52F2#.&,26&##6??@7:E'01%'H/C#'3?,=H<=--%'E;=&??G*5;:A6:E+6'B($F(@.*-%%11">>G2H.GC(&7%7'?,6"'"/7#=&4?#&7/H-(F)$ED8:@-3$9H/4G-@'6@0=6.4G3<::)+</,B";(DG-+H@;,6DC$-(;/G7&%(B?H8-1A.,27+2A8/D224G:),5"5-298)*9F==%"E8,;3CE4#.443<%'$;,"&D>;+.#->;B&G&.G"4'+.-)++*!!B2#4H9@1?@:5&BB:CB/C,3/+;C.:D2A93*@A(6(@G%.9E=GE)B1CG=>)2*<EA.(E:&#!H5%&<?
@r5457
NATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGNTTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCCGCTTGATTTCGACTTCGGGAGGNAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCATCAGGGNTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAA
+
$7<=B,A;$*,/07A<B$96DG1C)%!EA62=!/!$!2,9+86&AD<8F!9/&8/'$!E;D+@@&E#&$4B+5'HCAD8!+58B>)H6+)"AC**6$2.)G=C3B=G@7A%$7'71<2(=3G@613"1A,E".1E><692:5-B?A2.'$A&BA:0#6>9%FH,6A85-06<$H84<,6;#28*'7&A=!74D/!H*3'8;6D709E&>@'*BG#9B$F@25*EH7//&<7@$-8H<9E=(6"2,:'"*/<.G=E<>6G789!CD%E&A)10C)<%H@65?;&+G>A*!*.D'*A97:2:@D;'%7;&4:74(F-<$4C)(H5A,)#-@7*>"1$!,DD$G)*<=%6D'5$*1%23<34&.:.CF%A+59<:"H6'3@B!>9FGB?(#B8G$7'7-)=:,GB!#>!H-3@FBH+2A'!B;2$
@r5458
TANANATNGTTCCNGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACTACCCCTACAGTTTGATGAGTATAGANATGGATCCACTCGTTATTCCCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTATTCGTCTTTGCTCTTGCATTTTCGCTAGCANTTAATGTNCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGNTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGANGCNGACTGCGATANCGCGGATGAAGCAATGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGNTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACANCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCATGCCAGAGATGACAGCTTCCGCNATCATCCGGCGNAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGGGCACGCCCNGTCCGGCATAGCTGCTATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGAGTGCTCACCGGATGCAATGGNGGCTGACGTTCCCGTGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCTGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTNAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGANTCACGGTATCCGGCTGCGCTGATCCCACCTCANTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGNCATCAAGCTCCTCTTTCAG
+
**&&#%'*#*')$*++"!*'''&)'"&"%%")'($"&%&()"#%#!"$%*()!$%)(#&"((!#""'&%")+'*$+%&##'&"*%+*'$%##%!!(#(+"'&")*&')'&!*&(&#()++(("'*''+)")*#+"((!!(')+#$)!!'&'#+!+$&%#)""$*('&'#(#('#$$&)')%"#'""'#(')(%!#"*%$*&###%$'"#%''#$(+""!*$'(!#$%))$""$"!+$))%$*$%'%+(#*$&!!'%&'#%"')$'+%$&)*'!+!"(&*%%%'!)+$)%+'$)!&&'%()*)("!&"**#'#+!!'*%)%#"!#'))')(#+%('++&$#*($(($*(#"$!**)!'!"$+%%&+!')"%$!($(!%&"#(%%+++"*&+#)$!+%+("$+*%"'""&)$#*&"#%$+%*'*+&+!%!&*"$$''&%!'!*)"''!'#*!*#!$*)!('"&$%%%#*+"%%&((+!#((*+*!(%(!'"%"+*(!#*!!!)$!+"#!#+"!+'!(*'*%(&(*(#$!)*&!+&%)%$*##)$"(%(+#)'!+)%#!&+(&!%&+##$"*''+#)+))*''"!&'#$$*'+#($(%$"$'%&!&)"!(#)'*$*&)"+(%$%"&"##*"*(*'#*(!+%"#')%%$%"+")%&"!**&'$*'#)))#&'+%'*""(*)#*%'"&#!$**"+"'")"&#)"$"+(&"$+!'+"$+"(*(&!!*'&$"%*!$*)"!&!($*##"(""'%+')&$""+*#(&)$&&(%*%##**%$$(&&)"&'&!!!)#()'(#"$+*&""")('%+"&'&$(!'*)'*(*#*$(!$)+&"*!&'%#'&&*(#'&+%'$)(&"&!'"*(*)+"++"$)'!)*($"!(*'$+*!#*('#('!##%*+)%%("'%*"()!(&)"+(*+#&'!)%+$"$'**%'!!++%*+*"&')#')"!!"*&"*+%#(+!%)#'!#($#'("""'+"&(&!("$+")('#'+$!%$%$"""!(*"!#!*"%&*+*"))*#!&$(%!&&*('!)*($!!$+"(&"(+#!%&%!(##%'!(##)*"#$%$$#+'"#*+*!++"("&#'%##%"!"#)'"+&!!!())))"$+'$%(%+$$$&+*$(((+(!!#"$%*#&!%+!'%&#%"!)#%&"$*%$#++(+(#+'+'!"&**%&*!*$!)++'&*!+&!)*!!#*($!%%'%&+%%%)("*()'$+&"+&&*
@r5459
GGTCACCGTGGTGCTCTGCCCNTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCNGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCNTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACNGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGCCATAAGTCAGATCGGCTGAACTCCNCAANCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATNCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGC
+
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
@r5460
GAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTTAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGNGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACNTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGANTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCNGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTTGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGNCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGACCATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAAGCCATGTGGGATGCGGTGCTGGATNTTGGTCGTCCTGATACCGCGNAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATAAAGCGCGGGCGCGTTACTGGGATGATCNTGAAAAGGCCCGTCTTGCGCTTGAAGCGGCCCGAAAGAANGCTGAGCAGCANACTCAACAGGACAAAAGTGCGCAGCAGCAGAGCGANACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGNCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGNCACTGAAAGACGGGAAAATCCTGCAGGCGGANTACAACACGCTGATGGCGGCGGCGANAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCNTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTNCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGNNAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATANAGATGAGACGCTGGAGTACAAACGCCAGCTGG
+
&++%&"*)*"(+*)'$!''!(#'('(#(!!"'%$(%%!$'$)!**+&)"($&%!)!()%)$%**%'))!++%&**)$($($"!)'"&'$)()*&+%*%)&!+&%($%&&*%+%%%$+"(++'")"+'"&*&*(+%&((*+(($%$'()&!*%$&)"'%)%%)%#'%(&(+!*"*!#"!#!!('$*!#$"+&('%)$"+)&(#)!"$%!!*(%'$+!'#%)%##%)#%&$%*")%%""'*(&#$($'$'###'#!*+)%&(")(%+%$#$&"$%'*$$(!*!%%(+((($%(+(!)%*#+%%$%**"%#&!+)"("(%*&())'%'&(")*##+"(&%&+''%(&%$$!!*!+!*$%!%%*+$*('%)*"%"!!'(&&%)%#'!*!!$#&)%)('%*$)("!*+'$''!&)$*(*"*%")'(#)("%''#()$)+#*!*&!!&#&'+)(("*+&#)##"$&&(!$"(#$)+""+!%&$!'!'(&$*!"'"*#&(!"(('%)+)))%)!*!**!(%!+)&(*($()%&'(#*'+$$(%)"##$$%)+%#!&!)%**(*&'"$%"&'!"'()#*')$'+*#'')*!#*"&'"#()$'&!"$*)*$&!+!*+''*'""+("#"')*)%(#))#&*(#&'#$''$%(*&$!)%"!+++()#&")+**#&))"#!$%&'$)"%#$)##!('!&&'(#+&("""$!+$"+(*##"("*!$"#$*!)$'*%*()('')(%%!')!"($'$"$)"$(")!+*$*"$'+'**)'**''"++%'"'&'$!"$&&$&#(+)('#*'$&("%&($(!&+")($"("+&!*&&%'"&'&(&)+'%'!#+%##)"#''%+)'"(&'!+*(&"%#'$%#)%(**#)($("!$$'"&)&'+&%!#&++&%(#($*)#$)&'#*'%!(')'##$'!*'*)#"&%)&"!&*#%(&"!'*"!&)%&+&#$($')+&#$(%&$*&%!)(**!'!&)')&*%$&(('(!#(#%%'$)'!+&$%($($!&(!'$"#!)!*("'(*#&$*!)#"*#"#(&($$&((+$+&!!!(!!&%#("*(*'+"!%!!&&(("%##(*&$&&)"!#(!#'+*$)('$%!*'*%'#)'#%'(+")*'%%"*#)"&#%$'(*+(*%+&&"&*')*##+%)!+)%+(($!!$*((%"%+!#"$%!'*!#$)(&$(%"'!!%$'#$%*$*#$""'&%"&'*%"&!!%%#'#(""#'$''%'#'((('*$#**"*$#"+*)+!+&&#%$%"()&*'%++'!)'&#&%*+(&!$&%**+("!!*'$)+#*#&&$"!#&#&(*)#+(*&$(#"*(!$*&$#*'&$+($)&"$'&"%!+)$%#$!!()($'"##"$*!$"%)$+")'"$#***&%$'!!"!("%!$(*&$"''"*%$"'+"%(%*%%$%#$('&+&+""*$((!&#!+)''*%*%+'"")$!%#)%''&)(#!*#)*'$&%!(+$!(%%"#$)'%&'"$!)$(+&!%#+()&'#&$&)%(%)*+$'%'+""#"+)))$)"(*!''&+&#$(#+''"(+!*%*$%$*$%$%&"&'%%(&"&
@r5461
AGAATCGACCATTTCTGCCATCNCCCGGGCAGTTTGTTGTATGGTGCCGGGAAGAGGCATCCGTTNCCGCCGGACTGCCAAACGACAGCGAGCT
+
@'/%,>(C+=>G'/(3*HEEH)24GCF;?>@$39%:F$&!/A@;?%-H87=A<5.$A;9E6-7';C?E0#;)$F$%$#18>5$'6459#?<E26
@r5462
NTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATTTCATGCCGTTAATATGTTGCCATCCGTNGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCNATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATGGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCANCCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCC
+
!/!*+)%/AG-%/-">CD#(>9%"D<&46(GF8>&0C#'"4&(#)5"4?6F6;4+C3BE1C=06$2!-+/81.!#74->1D%#/FCH$@;!C3>3#E*!(/!7"6/:,6)*D:264ED&>@(CCAH/8=EG@AD#!1;<DB1-'3HG,5BA*)#,:0DE,E3G68+(=;:14&-04'0A(,+!&1%263-#G7D<>&>CC8<81+3/#E<163GGFA@%9/)?4,$?%E60B'<=<>&(%?"*->74D""'"$";;>7;9H.27!*)/F8#>>+'CCD&G64$?;!A&#F@750:1'2(E&83!*C?;'D,%$A@09&+AA0B!6,G?H-<3(DH=*=90C.D$=*9(&&F$&#54?F7=>5)ABC>.=2C4$+.$08.);"'?%&6@-+)-%=@<B(7CD,7/
@r5463
AATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAA
+
3H0BC&!$87B9&%"0?3A*'D1#C4/40.C8(F!H"8D(#3,97&@+(,*%.7G.1+4
@r5464
AACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGACATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGC
+
/<:3G&E*D;->,C$HA-*=C"7-:03-C>##B>594'C&0!%0D$,6?;=F.+>1E#2A3?(;=F4'(36#6CG.3D*'%8:*&%.:B&(1?!B@=#>."*<6=C5G/;"H4GF05$9>373D<D&B?639+=7/<$D99E3F'>@D=>"$C=B>$,"61/6DEG0-F3&
@r5465
CGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGA
+
E7@D,@?&'6E0&.'F,?(1((!26/?&>G@5!DH,@%H);=;2@8)22>-EG($*'$1,'?0GB(92"C!%A(3B"$#86D:?'A(;51$C(C&*!5-@"$9A3F0
@r5466
GATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGNATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATANACATTTGGTTGGCAAACNTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCNGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTNAAAGGGATA
+
0";,9A0>?@GFA,687(2.":E,2F0C>0)9H>10F"D&4'?=*)E6#,<C5%0=.4C''7D,9","B;B:B*730"0:'G6'5=+.%,=.8=>8.:3-,*9"F#'"(*)G/0!8;.5<(7"@H&44BE720C9<&<F(5@-B:4*FD1*1<0/;@C%%@#E><G/D:E9A3GBD;,B!,?=&?$2()@6G().&8$AF.G/$DA((0<&1,E"-(9"*$B:E//H)?"(44-'*;1/2;>@8"=,8"/&=@)7F!#9?,FG+4$$!-AH'H:F6H+0?BFE#<3+7$?$(F3-,3?*D7B>D/%F47058A//7B>#-7/'$/&E1+2CH"1#3,39%('#E3#68E>;4GH7A!F!(G/,:C@=(H$!D**-?.17!5#+.%'0.3:G0@"8?883%76C(:!7D(+&/E#!.*,=B">H4>:8AH+010.'&#;
@r5467
TTCTCTCCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTATGGTTCAGAAGATAAATCGCTGTAAAGGTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGNCGACCACATCCGATCTGACAGNTTTTTTAATCGGGAAAGGAATGTCA
+
D2@B).B(-%:'@"0F(0FE.@*-%%5(B@<?@::5%@,@834?96+1)/.6.-3@*GE*>#-<C6@&7$44-+7C&6:G)F3D-'>>H8A-<!7>@C>(08:;(7?5F7B9='4!3>BF-)=H$H'@3B4@(B=.@4@DA;/@14/H7EC)!:0%(?<==.*>(>$*(,"!2C'E#:/1?(46'+5AA"275<-G=;:G!,4?G;/.79-8'.>.-&.8972+(F((1A*:'%#7+%9!(,?%6+7=1:18>>H&1E:?$D@@>*"H#C!H=!FA<:*G/=1C,B4!*;#F
@r5468
AGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCA
+
="C75106'3AC">C8154E%)2-#0;F/(-A3AG:%-!B
@r5469
TGGNCNATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATNCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATANGAACGACGGCAATGATTGCCAGAGANCTTGGTAAACAGAACAACAAANCTGCCNGATANTGGCCTTTATTTTTGGCATAAATAACAGAATAACCACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAA
+
)&$"(+&+!($%#$*$(('($((!&(')'"*!*+&!'&')$+#!+$)$(&"++"""!!&+!!)"&*&!$#)&)(&'(''("!%!)!+)+&!&'*%%'()&&'""!&$&&&'#**#$%&+!'+("#'&*+$((*)"!%'&"(+(*#&)+"%$&&+#"%))%(!(!$*!'''(&'%!+)#)'+#')((&&')"*$!%+&"&+$(&%'+%)###)+$+%#%*'##*+'++(*)$&*!#')(!+'"%(%*#)!'#+"!+'(%#%+"*'!"'&!"!('$()+)*#*#%"+%)%$*((+%#%"'#(%%'(+)"&*%&)!#))))'+)+)%*!($'!%"""#$(#(*+%+#$)&##$))%"!)"$()($&!#+&%*%&$%+%+""%''$$*'#)%"+%'%!!(%##*($!"#')+"&)))!)%()(*&)#%)*!('(+#''%(!*$&%&+!#&)"(*!)**&*'&)#&+$%'(&'*&%'#%$(*$##(&+')"
@r5470
NGAAAGACGGGAAAATCCTGCAGGCGGATTACANCACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACCGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGTAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGNNTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAANAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTCTGTCGCAGGTAAAAAGTGCAGCCACGCAGACC
+
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
@r5471
CNNNNNGNNCNNCNANCACNANNNNGNTNNCNCNNNGNNNCACNNTGNNAATNNNAANNNANNACNNNCNCANTNANCNGNAAAACCANNNNGTCNTANNNTCNACANGANCTGNNACNNNCNNANNNTNCTNTACTNNATNACTNGGCCNNANCNAGNNNNNCGNACNCNNCANNANNNNTNCGGGAGNNNNNNANCNGGCNTNGNTANNAATNGTTGTAATACAACCGNGCNNCCGTNCCNGGGTCGNNANNCNATANTNCGTCTCNTNTNNTCNNAGNACTTNNNNGNANNGNNAAAACGGAGANNCGATAGNAGATCNNANAGNNCCGCANNANTNCGNANNNNNATNCCNNNANTNNACTTNCATNTANNTANAANNCNCCNNCNNNCNAGTNTANNTAAGNTANCCNNCNNCANGATTNCNNCNGNNNNCCCGNGCNNCNATNNTNNNGNNNNCNNCNNGCNNTNCGACCNCTNNGACNGNCGCGNNAGGTNNCNNCANNAGGTCCANGNCNTNNCNNTTTNNNCNAAGNGNNCGNNTNNTACCTGANTNNTCATNNCGNNNNANTNTNNATANTNTNNAANTGNNNGNACCGNNNNNCANTCGATTGNCGNNNGCNCGCCNGNNCGNNGNCCNNANTANNGTTTTNNCANGNCTNCNNTNTCNNNCCNNANNAANNNNCTGTNGNCNNNAGCAGGNTCCTTA
+
#"!#!"$#!""""!"$$#$###"#"""$!##$#!!$$"!"$$"#!$$!!!!#$"""##$""$$$$"!!""#"!#!"$"!"$!#$$$$$"$$!"$!!$$#$"#!#$#"""$!$$$"""$"!#$"$##""#!!#!"$#""#!$!"$$$#!!!""!!$!"!"!"!"$#!!!!!""##$##$!"#$$$#!$""!!##$#"$##""$#!"##"#""!#"##$""$#$$#$$#"$!"$"!!$""##!$!"##"!!!"$#!#!!"$#""!"$##""!#$!"$$!"$!##$#"!$#$!#$#$"!!$!""#!!#$#!$"#!"#!!$$$"$!!!##$"!#"#$$$!!!$!$!#"!!"!!$#"#!!!!#!$$#$$$!$"!"!#!"$""!#"!#"!!"#"$"#!#""#"$$#####"$#!$!#$$!"#"$"#$#!!!"!"$!#"!!""!#!#$$""#!#"!"!!###"$!$$$"##!#$"""$"!#!#$!#"!!$$!#!$$"$$#""$$#$$"!##"#"#"!###$"$""$"$"$"$"$!!$#""#$$"#!$""!$"$"!#$#$!"$!!$!##"$$$!"!#"$$!##""$!##$$$"!$$#"!#"$$"$!$####!!$$!##"#$""#"#!!"!#"#!##"!"!$"""""""$$#"!"$##"#$#"!$$#!$"!$$$$#$!!##!!!#$!"$$!"""$#$"##"#!!!#$#""""$!$$"$
@r5472
GCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCANGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTA
+
#&=1-+,4%'=#0#;@D>05G#@H.E:H:=28H7-+1EE-H4;H!H2-50(**:/6*=A0.C(37504A7,%7-*!+4:>HB8"14/=9>'<F:*:2%0*$:D=-14E<@E-/A=HC>C*@5<1
@r5473
TAAACACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAATTGAAGCTTTAGAGCGATNTATCTTCNGAACCAGACTATNGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAANTGGAGCCAACCTGCAGGTGATNATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTNTTTNTGCTGCGGTAAGTCGCATAAANACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAANTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACNCCTTGCCGATCAGCCAAAAGTCTCNTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCNTTGGGTNCTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTNTGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCANGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATNAGAAANAACAGGGTACTCATACTCCCTTCTAAGTGACGGCTGCATACTNACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAACGCGGCGTTATAAGCATTTAATGCATTNATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTNTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGNGTTAATGGTTTCTTTTTTGTGCTCATACGNTAAATCTATCAGCGCAAGGGATAAA
+
"#$*+"!!)+($'((%(%)*#'*(!&"+)*+""!'+'$#%%%$""#+)+%"+#&*$++"%''&$#(+)$#)"(())"$(&#*(*%*)"#%'%!&!$"+&&&"((!(*()"$(+(!(!+$$$($')"!("*(&"''*%+$&!*!++$*$(+)$*+&*+)'!*$#"%+"((+'+#"&**"#')"*'*$!(&!)!%(('+(!(%$%##&+)!%%&(*('!%(*(**&*)"#"(%%)+'#''(+!&%$""&'*"!''$'%+*%*%%!*%+%#)'&"$&*$!++!#&"$$)+)%*#'"$%*(+!')'")'('+!")(+*%+#(%('!&&%#$'")()*#%()'$"+#%($$"!!%*&%$%$$)%&"))*!($&#&'(("%#*%($!%%*!)%!+*"$#$+%$(+'#&%!!(+*&&'**""%%#&$$$+'*#"#++&%+#&(+((&'(*!&(%%%+&"(*+'(#")&"'#!'"%$#*$")+#*%*'*'&(*$)#$)#$##*+"+*$&'(%"+*!)$("%%#*!)'"+""&%')'%#((()&*!(%")"+*$"*&&"""+***$&$"&)+"#"%("(++))'("!'!(')&#%'''#&)()!#'"$*$%''()"!&!#+%!*'%%&''%"*%#*"*($%)*!%!'$"&'%!'''%+$!&$)*("+%((+'()%)*%)$++*$)($+$%+*$*('&&&)!&*'$%#$#'$+#+'(&&)$&%'((($&**!#&#%+'#'+("))&(#"%&+'($%*!%(*!*$&++(!!)(!%'#""+"%)$!'"!!&$+$++(+"&"+"$*"'*$$((*%$&%%#('%%#'&*#&"!!##%!&(($)$%$(*(#)$)*$%))!*("+)%"))%!(&**%+&(('("$#%$++$'#+#+#!'!"*""!*'%'%+'($!"!)(%%)+"*)***$$('(!$")%$+(!+*+&*&+!#*"*$"$$)&$+#'!&+"'#!++&(+&*"$###+'$)(#)'&&(&)*)"()+$&(#!'%$*(")$(""&!+(("((%&&!#$)#$#%(+'*#!)$(##+$#"'%&!*)!)!)'&%!$'('+"*%!&+"+)))$)+)(*&"%$(($"#''#*!$*(+(#(+&*)+(&')&!*+*("**("*("+!)%#('*)+%(*&%*)'!*
@r5474
AATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGNTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGNGCTCTCCACTGCTTAATGACATTCCTGTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTNGGCCCGAAAACANATCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTNCTTAATATCTTCAACNGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTATTTCCATCGATT
+
+"%$*%("#$$!"(%'("'*#&%''$")*%!&+"$("%**'*&'%'!()%+"%)"&%"+"'#+##&*&($(&'!$))*%!#$"&*!%(')"'"+!!$&(+)$"+!!#%&+#(##*&(*'&++$%$&!'!%'*))!%'%")%%$!%!#)*"$'#$('))(*+('"%+#+"*")'%"++&'&%&&&+&(*'*'++%'+(!$+#)+%)&%'#!&++!$!!#'!!"!)+$%#&*%$!(&$)(&$&*'**&'!+#"##%%$%$&)"&!+$&(%**&#)!$%)+!("#"%'%&(&#)(+*+"()&&#$&+)"'#$*!'*!#'&!++!'*'&"%&&$&&"#)%%&)!'#&%!)%$#&!%)*!#(*+($%+!$&"$'++"#&+(**&"&#")%+&$*#+$%!*+((&%%')""+$'!!"$)'!)%!*#)&)&&*$$"#$$''"#'$
@r5475
CACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACNATCCCGCCGGGC
+
;,1,:!@CA9'!D%&;<(5=/A/'%B1:?!336(&3*-F?24&)H*?(.--35>8(,"&60&38)';#7+(DA08@4B+!>'235"F@H3E?+DEF)B1;G,!1("8F;5>$5">D?'':%,H>$F4@;B;9;,%:HE/28%?#<9:7$0?8GF<0$)%H:(+3&.%HH@=4+1:;97$8A5EC,%=3?A0GH*+E'58
@r5476
ATNTGGCCANNAACTAAACAGGAACCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATG
+
(&#&&('!$#+$)&)#"(('++$!")!#")*(+)**((#'!%(%"&'+$(!%+$*#'"')"#'%*)+#$$)$%+!++)++'$'#$"'%#)(&#*('&#*'$!"*"
@r5477
TAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGNAGGTGGCGGCGCATCGCNTCAGGCGGTACAGCCATTCAGGCCCCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGNTGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGCTTGAGCAGAATAACCATGTGGTGNTTAACAACGACGGCACGAANGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGAATGACATGGCCCGCANGGGTGCCCGTCATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGNGGTGGACGATGAAGACCTTCCGCNGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCAGGGCTGAATGCCAACCTNAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAANATGGTCGTCGCGGGTCAGNATGCTGCGTGTTGAGTTCAGCGCAGAGTTTAAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGNATGAATGCACCCGTGCGGAGCAGTCAGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGNCGTTCACCTGGCAGGNGCGACAGTANCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGNACCAGTACGCGCCCCACGCTGACGGTTTCTAACATGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTANGCCGATCCGCAGCAGNAGGTGATCAGCCGCTGGCACACTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGG
+
&*)$"+)+%*$+(%!%)'(%(!&!!)(()$(!#$$(*''%'&%*!"!&"%#&"$&("#)*""%)#!"'(("'")(*&$*)%)&'')!!**+"%#&%$&)!(+#%+"'%#%(&()+++!((*+$%!#!*'"(!$#+&)$$*!"$''$(''#($!!!*(#*!+%"'++%%"&*#$*&'')+&!"(#'!$$%%('%"$*($!$*+#+#"(!$&*'#)")*(!+%)!($%&(+)*"$*'$%((%!'+$#$&%#*#*'$!*&&%'%"+%($+!%%$*%'!((&!*)"*+#(!'*%('(#&$)'%*&('#!'"*"!(*&#)"'&'%$#)")!&$'!)"*#$*!%*#()*(+$+)#))')##'++*%*%'(''%%"#*'%!"(*&'*'$!)$*"%")"(&#(&+!(!%!'!!"$!$"+*""%!(&!)"%!*&!+"#$+&!&&#'(')(%*)!(*)##!!*!!(%"#(#()$)$++&+&!!(*+*#'#!'&$''%!((%!+*(%(+(&%"+&)(+'*!''("$$)+"*#*"!$&*+%**$%$)'%$%#&"#!+%*'#!"+$$'%(#)%(&'%&"%$$)(#&&'++#&"'"#$"+%+*+!!$)#("#'%#!&)(''&*%!$"&$)(*#&&&+&)')(!(#!%%'"&((%'#$!%!%!+#"%((($*)'$&&($#'+&(#%%#!!"(("$"''"$("()!+(#&$"*#)**")&+&*&*"('&)*%"$#$$"%#$!&'()!(*+#")"$*($')$+*#)*%%%&"!+)%!(+"#&'*$*)+)('%"!'&&)!%#*(!!)!!('!!#'"$'$%#!"%)&+*#*!)$++$#&!($%"*'!#$*!#"%*#$%"+!)+%!(#!"&$+$%!'"''!'(*'('%(!$'&%+"%$&#$%''(%&)&+%))%'!'!(*%#+"&!$!"%""$*"'!''&*$!*%$*'*)"+!*%"")('$!$%$#*$&**!$%+%"'!!"$"((&!#+('+(#()&")($&"(%'))(#*+!+##)&&#!+"($&!"'$###'+!&)%(%&"(("!')&#+$!)%%)++*))%)$&($*!%*+&%)!)$!$((+'#*!()"*"+%+**'+%)!#)'!+*#$+"%')(((!'$"#*+%(#'((%#"(++(""!$')*'"&($%)%)'''#!!&+&!*$%'(+'%'("!'!%&'%'''$+*"!($!)&%$$!*")"#%"&$$&!!*))"$+&(&+$$&(##*+)$+*'&#%!+""(!(*#)+)+!!!+&*)"$*&#))"+('*$$'&*'$$%&!#!')*"$!"!+"$#*'''*)+&!#!('+'("")''*!%#(&!'&&)(*("")"*'(*!#&$&$+#(
@r5478
CCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTNGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCNTCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAANCAGACTCTTGTCATTTGTTTTGGTAAAGA
+
A)F5F(AGGF!/G9>3)@/FD@56C>=E"A03$!C1.(5B@$<8">1@-0.9E"6#2G51EBD3,@8A@)@<C@&C2*(4"?(9>:$4/02-2>@>.E9"7%=1DF)0$;E>$>;@H44-B;&<27#"9C;2$'GF4:D-38/$0%3#-5+("4HG1;D0128"1*/%5:871C8C%-$.6/#*7+C>1HHBA"A9?,,3(,E?H/@-F3F:?:?)G'3);,7$.:4&F/AG@!.&2.C%=5@#B'B#$1H.*&#FFG)3.#H7(,/2$8/5568'@9?4;"8?&@?0A3-21?G@G3A8+!#E>.@+6,=A0?D21&-99,F01FG$/@4:,HG%!)AB8-/A202FA(=A1#4B50
@r5479
NNANNCNNTNCGNCCGNCNNGGTTNNCCNTNTTCATNGTNNANNNNN
+
!$##!!$"$$#"!$###"!#$""$#!#$!#!"$!$"$#!"!"!$$$$
@r5480
AGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGACGCTCCACTTGAAGACATCACCACCAAAGAAATTGCGGCAATGCTCAATGNATACATAGACGAGGGTAAGGCGGCGTCAGCCAANTTAATCAGATCAACACTGAGCGATNCATTCCGAGAGGCAATAGCTGAAGGCCATAAAACTACAAACCATGTCGCTGCCACTCGCGCATCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAGATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAAC
+
@?"$9;)@>>02;H&;.!HA/*?$@)D9+9H=*(8@=&'&,/F9<D(&.0&!!8/=5-#6@9$)@$)48H'A@A0<B'D"6C&C+HC4)E1.+AA&-4:!9H6112-;%'.!;G1)22!A3*(!$3E)*?A4*-(8/5:AA-;DE+!.5)2;$3;*.-;=<7.E"=:HC&,4*/1*4C8,;?@9(<6'B5-;#%7/*4?8E8"=1E!:?@*C4:;)*%"D,-,<&>F!.33)3#-F1<C"&=G"9@@&E.%441G98B%>-:$-0!1&HD=C5,%=!:H9DC%5?0H<FD*:=G:-=<409@9&<&&&7>69&A>14/;-H,!#+C?=B0D
@r5481
TTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGNCTACATGATACCCACTATCGCCATCGGCATTGCCTCTACATCGTTCATTCATATATGCATCCTTGATTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCGGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAAGCAATTGTATTTATTGAAAAATAAATAGATACAACTC
+
9F>A05@3"&B5),D2/H&0G9/)*79(48H"E9.1-$A67=/$9=89%1"47#&E;2.75G%)=C/99.B$;2;04-/.H%'0:)$<%6;3#B@2,-"E5<A/%>5=&FE:<E0=351<C3C(1&C*28?<-#-4@DA#)&63">@#)/,6?.%C&"!E6<<B@/=*/';#EBE+<"9GA$.E*3B388%E9=40$G0276C'"/(6G?4A)%F05H-:)$EG<H@?(?H,4!D&9**4>E-HG+.&C%2"!8*"64
@r5482
GGCNCGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAGACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCTGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAG
+
@6E(:52>;9-:"0.GH'?'$+&9#8-E!D$7""B;+!.G/>;DG*H'H0..!F->9#E2E/;$3"@9A+*97/!.428/66*@7D4=9'8@H>%F3?<(-8(#E4/F?D4+D+5'G%?A)%BDA&B4:#=;=3:&@1;B#D4#@0(;1>H%$,;8?#2.)42E=H:D4B20#>40(D47<EB"%/"+3,.3"1D3?32H0,!7!#-8#;?;+A;;C!=+.F6#:+?&EH."C1)17?/*(E)81)?$4E67'(2;497+HGH)*3)$*:**D+/CHG57.'G&.)--:$CC0AA#0G,@3>0BD=2''%=D'?-9(<0=7=0B5;$00,D&8)8,D'*H@#E/FFGA+7;3&8/48!!7C4HD,G2<0A%>?+CH,,.*1063F)?$'2.B3*(<<GH)3$-(D>#
@r5483
GGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCNGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGNTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTGTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAGACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAAGAATTGGAGCCAACCTGCAGGTGATGATTATCGGCCACCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATNTACTANGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCNGACCAGAACACCTTGCCGATCAGCCAAACGTGTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGACCAACTCTCATTGCATGGGATCATTAGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTNTTGAAGGTAAACTCATCACCCCCAAGTCAGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGANCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACC
+
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
@r5484
GGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCNCAACTTAGCGAGATTACAAAGTTACNTGTCAAACGGTGCAATGNAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATTGGGGGATTGCGATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAANAAAAGATTATTCGTCAGAGCATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGANATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCANGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCGACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACA
+
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
@r5485
GACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTAATGTCTTCAAGTGGCGCATCAGGCAGANCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGCAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGNTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAAC
+
=!#!C41+>.74'.#=:00;A4*A+/?.?.02E4+BG!'C/-=2$%61;BH1'"F+=;FA,)8/1(3<@<9(0C(A(170+&=/(E'8>7#,!/=D:F*'"B$7(=H59!9(DF@7A/3=?'@@.=H(#'5=A;/(52+D5<'4>H(,72?<"A40*6117D4.768*:?B9/&%>$E+B20"4#.!B8C=0D$($8/C"@*09CH4,&E66,'GH(8:!&B:DH$5'EB.3*1+<6F64<4F2%66./A=@3*$#&4CH?D%FAF#"F(@*(H*.$#653.28=/.=$B-:.!:#$2@B,<=.B-D5H<=.7$37,3%4)H65(<>>"1F1F!,1G.";C/&9C560*2DG+-E*!?/B(=F/)C'806'7D%&;6+G;6GE?1,:<"DF7-!;;#$>C'08#3+/*)&&D.!85B($59"(G@!(6$?A!'??;5F46,"E#FA4>9'C97DE9,;?#2)*../36ED$<'(G$8';=#
@r5486
NCTATNCNGGTNTNGNGTTATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTNACANATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAANTTATAANGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCNGCGAGAACTTATAGCGAAATGNTTAATAAATGCT
+
"&!!(!$!(!&!(&*!'%&'"++%&&%$$#"$+'$#&")+&&"+(#%(#&%$&)'($$")"#'&(!%'(#%&%+$**')&$*'&*!!*+)'*!*#'&!+*'&&%*"&##%""'&$$(*+!++%"''&")%$#'$(&*+#"$#(+#'('"'!)'$"!'#!%)!#$+)&%!#*$%"+!((+"($##$'''%##(#+$+%%&(&%)#*)$$()"'*)$!#&)*$*#!%"(#%!+%"!*!*""#"#')'*%*))$%'*%*!'')+'!#$+'%#*'$'!%%"(
@r5487
TCCGGTGAGCCGGAGGCTATTTCCGTATGTCGNCGGACTGGCT
+
#+$%")$#("*(%!$$%("+!&+&$#("$""#)$))!$)"*+$
@r5488
ANATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCNCAAAAGAAATTGCGGCAATGCTCAATGNATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGNCATATAACAACAAACNATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGNTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTAAGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACANCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCAC
+
)#+%'&!)*+*$&#''*""$'+#"()!(+'!$#"(+#$)$'"$&!**&(!&$#!#()%*)+%$!+)'!*#(")($+'(+#"+*&$&!!"(%&+)"$"+'*("++!"!(!!&%%&''$$'+)$)'"'*$++##%#"*($!+)")+*)$)%%#'$"%+(##)*##+*)%&)##%'$++%&(&%&!'$&%%(#+$+*&&"!$()((%#"%!*$*(&!#%*#)#!()!%'##($$''"'')('"&!!!''$)"#*%"#'(%&+#'+")*#)'"$%$'')&+&'%+$(*)%%%"#+($)!*#**+(((%*(!)(")%'*$)'%($&*'"##&*&"#&#!"(*!$$+(!))'%$%*$(!!%'#)#(!$$&('(""!!*!++%++'#*''!#&!'&(%!)%&%%'"%"#*#"*++)"'##%($+$")*)%*'+*)%%')%$*!)%))""%('!&'*$%&)#$$%)("&!'((&"'&*!%()+(%)'"%()!))%$#!#!+%("(#&+$"(+%+$#&%+$*')"!"%!(('##)$*""'(+&$!+%)&#(#!#"!''+#*(")&$++%*%(+%$$+(*'##&&+)++&+""++'!++(%&('
@r5489
CTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCACGCCTGGCGAACGCGGCATAACANGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATNTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATACTATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGNCTTCATTAAGGGCTGCGCACAA
+
6+!)C+E6#4+40E8$%F(C=F)?)*2939G=AE!B:0'&>3G5!9!?>1<B)G"%/>.%E9F'C#1(F1FC-#58H(/!=B@;?(.;"E4</D)E#+,28(<$<"(9<7"C4%!@#F)>!C56<>.9:<4G(=E2C+C?E5$@D+>*8*+,-@-?9&#='9BEA45E>G9B?;:.#/?-4,6F;%0%/.C'2GB5;-!+.D2<C#C+'!D05>)D#+@F13<D=><7#F4)??H:DC.):=C)B>7/95"6'&5&2<@15!#9/B1C5$3&%E/!EB=FB<=5EC6?,9<,&<3;@3)"<9@*"E'D)?04G8HAC6B)9%.)'DE')!$>$6$2A.5/F@@D@6=;G?@0,E"#>H'00<
@r5490
TGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGNCACCTTCACCAATAAATTCATTAGTNCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCNGCGTTA
+
G<0*F<@<9-2/(H"F9/1:/@$C(61=:G0,@#0AD4=?*G7=<!%4F;B0'<"-.?3914&E#7;C#9.G$HD?3F5H.9.%F2?5+$!7<D>(/2='<5C>$*18@8HGE:B9D'D(?,<A0"<4;&B:16F%<8@),)-E"565F5/>E=@<F>B3/<>"4#=E!8HFG8%&$?B*-C;**GE<AD4%2?3/"#2B*!<2>,34G49
@r5491
AGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGNATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGC
+
=7EBC&?-<65A:)@%4(#(6:?3(CF)C0&:4E#F>$CA0+7"&*2:%->8"G@DF;.$6,4)$10$)12%%-#E172=?'>4-
@r5492
ATCGCAGGCCTTTTTATTTGGGGGAGAGGGANGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCA
+
#(B/GGC<7<,E!3'(57!GH-<)9(5<H79E5E"E86),6>!12C)H(:/"!#-D#!<54@%>7=??$>2<?#/#8<>
@r5493
TGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTNTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTAT
+
G:D3B'A?H0B/6#">'/%D?*,&-*;"*)EG-E46A($A#:A&@7476A36>#6G..(+?>+$+*$2+=7&44&;FG+E/17F+*D%,C'>(52CGG%90"7C,B6=H>G%15.)4EH"*@>7>;5!'%64B=6,0)%=)6+))E+'%2?76?
@r5494
ATCGNACACGATGATATTCACCACACCGCNGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTANTCTCCTCACTGCGGCCCATATCCACCTCAACC
+
+H(:6G-=:%C42*<),#+8$=*-2.$('A1**&24)7E:85C>'*+14/#@8=<9=7F65;05-/F!5"@@<0*/.-45+3>EH,2$@60/$!!A?%D8"2$0*()H/3">/4=9FC(F.-DG+A:D5/(8F*4!>82H,A=/@?3+B8/,E5E)8
@r5495
GACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTNGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTG
+
-9(@E4H?3@;G-C2?/5#C5@8E3)$<$60"0#!60&F'=9D$+F.9<E#'/%E6FH#/.&B1G8?F!%@0#&),*89%?'4;4B)=?@,!B280#'6?&@4#$>@;@#?+(2<8#)(F?H@"36,
@r5496
CCGACGTCGGGGCTGACGGCGATGGCTCGCNAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGC
+
GD3=C:7*2BE=1%6@@'0,1'184'9-+'8E<.@6C3#.-(,*>0*=DB*,;<&3B@(4$;<(4*7=#%"E:HCAC.:H17,8%,!8ACAE-5DC>88:,/E#*C;@&-8B:)/%<5/.5?&4-$'-@6+3<D)5:$H5&68A5&0&>3%=@;9:2A*5=$"C.;5C67%G!@<31H'?,&!$C7!.(G.)1A
@r5497
AAACAAGCGATCGAAAATATCCATTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACGTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCCGACAATTCTGGCAAACCATATAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGANGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATNTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAANATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTANCCCTTAATTTTATTAAAATCACNGCAATTTATTTGGCGGCAACACAGGATCTCTCNTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCNCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAG
+
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
@r5498
GTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGA
+
>,E15?.B3*81&E/8;5/(*>)66;=:;*+GF/58H@*C8.8,8*H9/*A2&=?:B67,<62"GF@!B=23&C55H,!4B&6:+?;>(7H97B:/+(A0(8-<FA<@44-3EDA?/7:1$EA@&$,C?A/;)-9D0H@!3+/C!&.:D%)/0#E3C<9*$)0.C(#'+-G"+)2&<*<?(:=(;8*//+FE(E,<+1*E(0&-03(!"=C,*@.=BH-0&959!()>3#:B#3+035@7*A*@06'%=:;5HA$!7?("8!&/,6C:52-3<C/67+3062)+1)'9B=4,B0>/7A32++5A/85.1>5=>E+
@r5499
AGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAANGGAATTATCACTGTTGATTCTCAGAGGCTTG
+
>2E=H&F%')H)'@/.&#+9G:"./B2E376/<-9G#?F%6B/4E!5G9C")7?1=.;HF?4<8;.?.@3(B%%B#,,5A+.&5@4:5C%/EG+@@6:("BA1969;@C@$?7/?77.$(0+E2:""<A+G)?7HG,1BE8DH&6G08,>.#%(
@r5500
CATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCGTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAG
+
>(=>>80F/-FB4=.)05-E-3$9B#F0CH8<;A"+GA(C&B3&-C$A:G.:/@F:=B<357@G&B;;13B3<H,BA69510&F+>8(094>8?.!9-,(;,")>.7A8.)5A$!3?.EBC>2-#")<0##!2=830!=<@3'B"G,-)1$:G1$@E*D1.$!"4=E'3@1FB%;A%E3B')3=)HC*$!*H;F&+-A(@F/(."5(<=A08,(>!A+!CGH4,D7B:/+C>?,,-@B>G6FH3F%/#.'E<1!!/>*D9EBDH2F><:17%:?A,:6,G;&2D$%C;*BEE500H/"/.'$:969(519F+4&$3=;91;)((*;A%A:D,2A>='.+-*F:"(+(-+(90B!&?,B?+;$-7.+.17@8AC%G")A47)-8;)5$15:)A=B'5;ADG5<;;''BE@,%7A6C?.C:#/?2#=,H'B8!DDFBG=<63+=HH,H=CG4296
@r5501
GCACATTATCCNGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCTTCCCTATATCGACAAGGACATTTTTTTTCGTGNGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAANTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATNTATCAGTGCCTAGCAAACTGGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGNCGCTTATC
+
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
@r5502
TGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATNGCACCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCNTTATTTATTTCTGATCTCGGTCCGTTACCGGAAAATTTTNCCTGGTTATCGCCGGGAGGGNAATATCAGAAGTGGAACGGCA
+
B751:#2/F-/(15A&(%#:1=6A*0)*/;2GA/3F(D(,&"=1E?+50-DC=8,7:)F#'$<&6$+$*%04;:568/:%!5,<B(!<D&E7+(8H'()*574!7:(;43G<GH5!AFH3#7@H6:$C$8#!G&6!"GFA:!>!-DBB3G4H<(<2=8G4?9G?%GH+=>C'+BF29;3);.00+0)8227"B34<72=0;$/7!/6GFH5G5>>E8EF3-*#@"$AA?%C<./56@CF0H=6B6G$C1.+4#!++8D<CD3%8A*<@4$@??.&0=BB6
@r5503
TTCTGCACTTCCAGCTCTGCAATATATTTTNTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTAACTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCNCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGNACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAACGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTNGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAAGAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGTGCAGGCAATNCATGACNACTGGGGATTTGACGCAGACNTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGNGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAACGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTNCTGTTATCAAGCACTGCACTGGTGAGCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTNAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAANGGAGAGTGAGATCGGTTATGTAAAAGATAACGCTTGTNAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGG
+
#+!")$++"+#+)"(#'**$&%+++%#&$'&#(%+!)%(!'$&%%('*!$!"&+!&")!*##*+$+(&)'$#+%()#&%#(%&'')$''&*"#(#+*+('!($#&($''#"""+&*$!!''&!%!$)+*+)##%'&"+('+!)%*)!#)!)#")"$(***!*((&#&$'%&%*+"!*""$*))+++&&+"$%)'%'&!&*%**"'&)'!%&'&)+'&'")%("('"(&%+!%#&(!)"'&#'%"#"$%)**"!$&!%*+!*+%'%"*$&%+$!&'&"*)&#'"&''$&)$"$+)(%(#((*('%%)"+'"&!%%'(!&)$#&+)#%+*)$+%(&!)&'+****((""#)+&'#!"$(&+")*')+&"!&$"*!!!$#'&%'+)"*#("#&%+(!+%)%###!#'%)++"&'#&)(%$&**!!+$##+&"(+')$#'(&'!%'$)&#'!")%'#%*("!*&!$()()$)'#*#$"'$$)"'!&!$&(")+)+"#*$&!!&"")&+"(#*&)%#+"&)*($#!"+!'(#')!#!))("!*%("%)(+)%$+)!)'%*''"+&+!&(*"*+!)#!$"#$+##+*'#**"'*+*"#('"&$&)'!#+%++$#!*#+(&&$$")$+!++(&%+)'$&$%+%'"%"!+!%(#+$'!$*&%*"$+"""$'$&!*)"+%"+%#"*"'#!!%)'"!)'#)!%**$!$&*%!&'(!#'!()#%$$'((()'*#(&"(&#'$*#"&*+(*)+%&+(#'"*!(%)!()""*+#*!$!&'+(')"#*#'#**($"$"&((%()!%#((!&+!($"(+%*%"+"#)!$!)+"##$$&$'%#")%')'*!"*&'"'(+%+'"+*)*#!*%(#*+'+&#+'"*&##"")#&%'+!"')'$&*&+'%&*"*)"+)(((#*+&%""()*$'')%&'"(#'+)!!'!+%#%%!*)(('+$!*&$'&%$#(&&((+$*+!("%!!&*&('$#*)'&#'$!$%#*"("#((+$(&'%"$$$%')+#("+$$*++!('*#"')"#%$'&'"(%++#('*%##*)(("!&(*'""#'"&*!+'!!!"*"!'"($$'(!&+$%"!(+$#$)#)!#"(!""!+&(+#&(*+)#!#*!)##"*))()!"$("!(
@r5504
TCTGANTNNNACTTGNCNANNNTCGNCNNTNCTGNNCNNNNANNANGCNNNCNTNNANNNTTNCNGANCANTGGGNNNNNTNTANNNNNGNNNCCCNNNAGTTGNANANNCCCNNTGANNTNNNNGGTAGNNNCNGNACNNNAGNATTNCCNGTN
+
$##$!$$!!$#$#$$#$!"!"""$#$"$!$##$#$#$"!!$#""!!!#""!!"#!#"""#"$!$!!""$!!$"#""##!!$#!$!#$!!##"#$##""$"!!"##$!#!#$!$!$#!!##$!!#"!"$$#$##$!""""!#$$$!$#$"$$!#"#
@r5505
CTGGTTATGCAGGTCGTAGTGGGTGGCACACANAGCATTGCACTAGNTTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGAAAAANAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATTCTATGTTACAGGTCACTAANACCATCTAAGTAGTTGATTCATAGTCACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCTCTATCAGT
+
00H)%-7H"*.@*;/)(6F=BB="'5'D"*($/7.57"46%*.H?33*G63/9()5,,8!C/&&!,8$#$-,-46*?$:B-"8*%90C%;6$/!#!5:BG).0/<01(0<CD9B%5EA;%%E.2B?@!6:3E#%3)G*">B3H=(/'."'D413-!0&-3+/6:!G"0;(AC/4;-@)$&!6,#4'EA->/4HHH$H%D3#541#1)5!D1=B,G>+44$&0D:?0C75BGE%/+$3(40>23?E1,3)&)+'A-/6AFB'7BD,?*-B;@A;,H14789D3BC-(464'"*@"2.-+#2&.D&EB0(34B<)78#?(17>H=5.$&6G?=8EC@@<3#D8-9-4D=
@r5506
NANANCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCGGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCNGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAG
+
#%!((+%$(%#$*$#*+%$$"%(!+"("$)&"'(%!#!!+"""#"+&(*)%&+'+(")""'$#)!*&(!!#"')#!))#$)'!(+'!'("%*)"))$+'!!*$!+++'")$#+(!'+'")!(")*#'#*&"%#!'""'"(&+$%$&+&&')%%%#)$*$')$''(("#)
@r5507
TCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAG
+
6(%DAF@@BE/:;6H3'B$/!8,<$762??!<%A,H)02%:F$>&"@60-E7)D48>)")8<3G=AD634#1)C5/+:,52G9*4?5G*'2G:'%A@71@#.-:.'C)A'/="%26%@=A(/B-BE79A(1)";B-1?1&!DF<<8?A>%&*#/(+2*659'4)3!'.D?-B.D&
@r5508
CGTCGGTTNCCGTAAATCCTCCNGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCC
+
)"(%***')+*+))!*"#*('(+&"#)"#)(((#*')''%$#*(!!%'$!$$+&(*()($)"!+('$!"*'%'$!(!+$*&#%$&%$!$%&"#**%"%*)!%#+*+#($&$)%#&!)**'!**!+!#%+##'
@r5509
GGCGTCCATNTGAGGCCAAACGGCGNCTCTTTGNCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGC
+
5A@5>'=('6A7&F<,EHG;1*#G2GFF<:54<"+EG-9H>=.;E-!%CHG"'@)+9;C+B)H;E,7H23A-D7."B76A.>'DG&-:74
@r5510
ATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACNTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGNCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGANCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTTGGTGGNCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAA
+
)2.B;F-8?<?/,(3@>*9;04,/B10HE(+5D0#:@'9+'H5<$4"-6<,'-=3=#6A$-0C1!4.8A9554@500E8H7CEE-:;!BG9!D+DBE$492C!<%FH+8+((4+2==3#=@->=7/%/,&F+1"!<?.5$8$A8CA>B+>:;@,):!D'&62'*$D8(!3559'DF&F.*7+BA.G(7C7F;<-#7/#%7H$A1/BC4?E"50,6G/>"#%H9"=!&&"H$F'(:%*58><4.7A94;,46*$F.'10)'H;8@"E;$DA6;E;H/GE)&4-DH;!'6=,B=9,18,;997!;:2EH$=!.5&3C5$3HE3.-*!=#-85@@#%07*7F1$2/E)AF9#&:66.'*7='BE6"46)H?93G23=HC)<0G,FC,A$<E!&CF;5H=96-$<D638*6=@%2$2F90&A5E.?87$42"27>>*D.6-<
@r5511
TGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTCAGTGAGGNCGACCGGCGGCTGCAGGTGCANAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTNANAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGNCTGGTNGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTNAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCNGAAGCCATCCGGGCACTGACCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCNGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCNGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCANCCTTGCAGCATGGGCGGCAGCCATTGGGGCCGGTGGTATGNCNGGCCTCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTNTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCNTGGTTTCTCCGGAGATCAGCACGGCAGACGAAGGGGACGGNGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGT
+
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
@r5512
TATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGACAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTC
+
AH82'><'6A;*'#C<G).(G"?..7)B8-%%1C+%AA),B3H2E8E-GE@)9"$(G,.?'@$$/#>6334=?*4/'%-(C9;.H8'B175*H+,)'-8(0.9*.9$.:=@6=0.@03)!,4-08#1$!@E'.%F;?AG3!>;=2,G9E9/B=!G%D%.("D;0-H-67#8E=2*7D#5,$5"4'B)ED*")#&@79("9@,'.,'5<91@4+&G9=#%'D,>)@;AE-/C3=8,""2<E5!#;8GH&=6!(>(22>(*!(,D?/"D/0+#8.(H+<-5(F+(&7@=*>/
@r5513
TGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGANCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGC
+
:#1,,:0.!G6E#=>#-21?C"C&0$4F1=-DA;*!,$<9E#AE7:>;&H)3E&!;%:<6@=;,75A6=@?:H:;15/>,9(4BE.4$A7"8$"&=
@r5514
AAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCA
+
<-14-"$5968;%"+35$=+76=2@&G'B2&:!(8+(B!8A&F04HA%G)0:4;=(/
@r5515
TAGGCATCCCACCAACGGGAAAGCAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGNGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATA
+
+!;0-7$4AB>*'5&A);49$H<9A#FDHH47G?6A<2*D(#8*A6<G"0='#(!0#>:>:?F07?'&&$:D&G-C6BB#&!88F5$"@B4%(&>CBG/;0%?2#8?G9."B3;(>>E/-@>HA&B)9#C7&H=
@r5516
NGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTAACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCATCCACACTGCTTTCACGCTGTCGCGGNAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTNTTCAGCTATCGTCACATTACTGAGCGTCNCGGAGTTCGCATTCACACTGCCAGTGATNTCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGAGNAAGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACTAACATCGGCGTTTCATTCCCG
+
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
@r5517
GCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCNGCCCCNGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGANGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGNGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTT
+
7:4<B;>B/18*.+=))H/-*;B!DC,##G:9>%$!E'"<E9)%A*,))&;('!;:D3-(8%06)>62H2+"DCB3!,47$</$2+"@5.<)C<!E$&F"1C7D<EE>9&6,615G>+23=?-H%"=&HH3).9.2ABFD3%6'.E)B&#57E'7'E24',&!9+50951GDA=A;1*6#HG+%B:E./B3BF0H@G-.,7,E"9@<GCA>7"G>?@&64F+84#)=%=1-C/7'5F*A'=.24AGB8-#5&+%!&?*G2GC?:'=G"-&1=8>,#(=$$3&!05'"%#@(";!57=(G@-6+"12+=B(1A73FC>3>!!EA*:)";E-;*B<>-92;/0C?E.>>7$BE%><,2@/B#F>&,HH.76A?&'7<,;>552/F3BE(:.1-11-,0.%1:6D!(7C!G>#1125GH8'!6A?.!G8@GD'.CH"#@1/1A?#.F<&B4;("%*5<8A50
@r5518
CGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATA
+
&5."/CDH;,%;CCF?+1H9:B(B-1)$85'2<74;"$EF'3$3.HC=.H"#3,/G'1C@-=*0"*H$,7#=43;&D+13$;67'*AB+'4%H(-7;/;84!3=&'=533%',;C>77&34,H<%70#<*5<?AH8-F$D/HC-)
@r5519
ATGTTGTCTGCGATTGACTCTTCTTTNTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGNTNTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATNATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTG
+
4625%(;87&554?76>03C07:#3+4;%'F90."110AGEB-&G94?(F""71=6,/:'BD>4C(DBA:;(4.+@)4:D84H21HA,D(G*57<%*+&=AB'@GD'0-)>$%-;#2BC>5D##D>-$8GAC,@?B7%,3=5>7<3C9>05.%,#=FDD$+EC6H08..#<%;4:FF*'#?><!(4A&B)+7;0E-;>@.-72;A*/+@(-/E278>8)(##H5;8/,33#-=%%1A7&H@5&?A%DA=*.=F0!'#8++HA%03A7H"$F$FD972;<27<6=/%D4E';6="2C'">E7(*44D.1<.0>(52C(+4?AB57F
@r5520
AAACCGTCGGGAGAGCAGGCNGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGATAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTNGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGANCCGTAATTTGTGCCACGCATCATCCCCCTGTTCNACAGC
+
+>D/=3EH+$!+8(>+9(6D/$?"?+$7G;::.AC78"3CE0C%,,''+9=:(45)-DE*GHHG81'B"C7@<H964"??)D:&$#/9'-->=;D0;=&'&G<@,,3"(;76;:"5-$=5;-'B,-6H)HF;@@'D>+'.0;$9(B&64>%6#FG7*+/?%B==E0*&>)?)0EBC)4)8;'#=0!4%"$1/?.F7%30?:@B8!#D.H0-;@(<H7=//527-49'(8)="';F7C3C1<:93E6*6B,G+9AC1B6C8*=4-;$:0-5@6<8-D?>-;?A/C)=>5===4*85DC*C68)70-)%'H+&81&0(+
@r5521
NGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCTGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGNAACAACAG
+
",D732<CFC/"$$*#E*G$'4)'%E%@-<+B<'6&291B&>CG*>1=5>/:&F8F$7AF18:8+.(?-9*2D$)/5;26B-)FBA.:,H$4&?9G>H0(,+C+&')5H:,;EA8?-=,G+G/?$F;#%46*==14:?:3F3#A*70?:"C>(>30@C,.+>:-!(;46.,D.(>?B;<@AEE/G&*A=H8<E>)7E@>7$C*+41751&/63'<.
@r5522
CTGGCNTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACNGAACCGTGATGTCAGTCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGNAACTGCCGGTCAGGNCACNCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGCTCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCNCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCANCCGCCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACNGGGCGTGCGCGTT
+
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
@r5523
CNAATNAATNCNCNTACNTGTTGTGCAGATATAAACCGAAAC
+
%)&"*#((%$)'%!%'$#+'##"$+%%&'&)!'**!(!(+'$
@r5524
CCAACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTANTGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACNGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCANCCAGCGGTGCC
+
'$$%'+$"(*"(('#)%++%#!#)!+!!&%#!!!%&"*#")++*#!$!(+'+("#$#'#+((!"$$%!!+%&%+"+#&%)&()'+#(*&*'+&#*!*!!)&(('+)*!%)&%!')$'#(&*!%)!%+'+$'"+*'#$'&&)!&$'$!"&$&!&&$!'$&""##'(!$'#(&*"(+!#+*!*$!'(!#%)!+)*$'!$$!&+$!'!$*""#+#))+&*'&"$#'"('+
@r5525
TCTTTTCATCTATCTCAGCATTGGTGACCTTCTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAANGNTCTNTTAAAATATCTCCGGCCTCATCTTTTGCCCGNACGCTAATGNCTGAAAATTGAGGTGACGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTTTTAAATGTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCNTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGNCCGATGAAATGCATATGCATAACATCGTCTTTGNTGGATCCCCCCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGNTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTANNTCGATGAAGATTCTTGCTCAATTGTTAGCAGCTATGCGCCGACCAGAACGCNTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCNACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAG
+
**%(("&)$*)'(#+)%$"!'&$%+#$#%*&"#'+(&(")'*()%+"$*#$*#!#$%+*(*%%*#("&%%%%%+#$*&%"*&"&!'+"++!!+*&("!#)')&%"+*"&!$"*$%""*')))(&*''$&&+%$)))(*+)#!!$(*))('(++#)#('#"!+##"())$$+$'#+(+!*#)()!*)&*+$#('(*#!+##)+!$!&+((%%+%#*(%'&+#*!%"'"$"++)(+)%$!$)#")*$+(*)&!"&%*($!&"!(+)!&&%"(#**+!&%(+##&(+*&#%%#)(!)&!+(")")&#$*+'*#$%)#%!)(")#&)'*)+)')("'"+$$%')#"*)&#*)&$")$'$#!#&+**!$&+&$$!#$'#)+'%&)%*$!+*(+$+++#*($((#(("(#$!('%&+#&%")(%$("(#("'$(&%'"$!#+$(&%'"&&$(*$#*!$$"%!)!)''"+""("$&(!"+!)*(!*&'$*&(%(($**%'%*&+!%(*((&!#(!'"$'!$+)$&!!!++()(%%$'#""#!*'!&"*#&%')(#$&%&)&"$+##'))*!#)###"'%')(#"&#&%&*$*(*+((+$$#!$$&+*('#')$"*&#")(#$)+%+'#)"*($&%('&+#'&%&)$#('"%+**'%"*%$$)#'$('+)$&"%+*%+$!+*'!($"%(#!#!'%("$&*)'*'$!(+")%)!$$!(%"!&+'*$'!(!(&%++&#("!+)+(&'%+&&'!*+"(((!%+'!)"'(*'%'%+*$+""'!)%!!&"!%*$!('*%!%)*+)#+$(!#"!&*)$$!+"*++&!)$%+&(!$%&)("!&&!))'%*&"#*)'%'!&)$'*'*')"''+!!##))*!$$+(*$(+&#$(&)#&&&("*$'!)$*#!"$(%"#'+)*)"!#"*%%(%++)$&&(!&!"#""+!&*##(&#*$(!+)'!)&'"&*$)%"$##%'#"!!#((%)+"")+#&!$*'#$''(*!$*&#(*$"#'$&(%)!(
@r5526
ACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGCCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATNGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTT
+
G/=@:79H&C$"-?#(5#(@DA"6/:G,,-<>(-:DD)!=:.0!527.'#2?74C#*+AA-'(%.;%'B&%0'?0.A90C155A<'0)?9E/%AG%!0;0<-A*"G*+;+37>7D/81F2F.2:-2:G7*<<F8,@0*//(A6&18%2)<0*=69!',1.F004))E8?*?$B;G-4067&&D>8)54G@,CH.<9F"7?#BH-%;#9$BG6&"&
@r5527
AGTTCACGACGCNANGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTGACCAACAAAA
+
$$&&'(#)&#*#((%&'*&+(!*(+"""&&(#()*+*%+!!'#$)##)++$$"$+$%()
@r5528
CGANAAAAGNNTATCTCGNNANNCTGCTANNAATNAGCTAGCNNCNCCANCNNTNGTNTGGNNNNTANGNANNAGNTGCNNCNNTGAANATNCGACNNNNNNNTNANNNCNGNNGCNNNGCCAGNTTGTGTGCNTTANTNNCTNTNCNNNNGNATNTGNCNNNCNNAGNCGNNNNTANTNGNNNTNANNNACCATAGANGNNNAACTTNATNNANAGNTACAACANNCTGNTCNNTANCGAGCCTNNGNNNAGNTNNNNNNNNNTCNGATNCNTGNTGACNTGNNNNNNANTCGTANGNCGNNNNNCNNGANNNANCNATGTNTNACTNNANGNCNTNANNNGCNNGAGCNTGNANTTACCNNANNCNGCCTTANNNCNGNNNCGCTAGNANTGNANCACNCCNNNTNNNTNNNANNNAGTGTAATGACGCCNCACTGCNCTCCNATNNGGTCNANNCNNNNNNTNGNAGNAACNCNNNNNNGNTCGTGANTTNNCNNTGAGCTTNNGNNGNTCNNNNNNNNNNCNCTGTNNTTTNGANNAANNGCTCCNNGCGTCTCTTCNG
+
"$$"$$"$#!#$!$"!!#$"$#!#!"$"$!!##$!$$#$"#$!"$!$##"""!$!""#"##""#""#!!!$#$#"!$"$"#$#$##$#"#$!!$$!""##!$#!!#!$!#"$!###$"#"!$"!"$#!$"!#$$$!##$!!$#!!#$#$"!$!!"#""$!!#!$!"!!!"#"#!!!##$#!!""$!#$!#!$$$$$##$"#""$#$$!"##!!#$!$$#"$##$!!!#"$#$$"$$"$"#$#"!#!$$$$!#"""#!!#""!!!#$$"#"#$$$"#!#$!#"!!#""!$$"!$$""!$$$#"!#$"##$###!$!"!!""!""$!##!#!""!$"#$!$$"$##!!#!"$$#""###!!#!!"$!$"!####$"!$##!$!!#"!"$!$""##!"$!$"$!""#"#!!#$$#!"###!$"$"!$#!#!#"$"##$##"#"#$#!#!!$#$"""""#!$#$""""#"#!""$"##"##"$#"""!!$"$$"#$#"##!!###"!!"##"#$!$"$"!!!#!$""#!#$"#$$"##"!$#!$$!!!#####!""$$#!$###$$#
@r5529
CTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTANATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCNTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGNAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTNCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAAGTGTTTTAACTCGTGAGGTGTTTTTANTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATATTGGTCAGATAGGATTAGAAGGACGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATANATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCANTTCCCCACTTTNTTGCNGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTAT
+
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
@r5530
AAANACGNGAAAATGCACGNCATCGTCAACGACGTTCNCATGGTTCATCGCGGATGGAGTGAAAGAGANGCGCTAT
+
&((!%'#$*#)+%%&'"*')+%"+$&$"$"*#"++'&!"'*+&"+$))'+'**('+'+&*!)'$&%!*$&(&$&!*
@r5531
CAGTTCGCCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTG
+
7B<<E@FG8;!-+,;?,&F44EHC0.8G/3$&7E;<,9-HA>D21E/&D:"31>*B.4*!7:;.A$$1G0=.<@,1+H)A3.3G<$G4$H-#/'-&*A@#H',"3H+'B(='25&*C+?@/986?#%$B5?0)%4!!19:!>*4C99.!-,@D:*?0#,02@@&,D"*:16.26&*+:$D.!./,'3#F6B>6*;2)!<,F!DHGH/94<DC8>E:67#!&A9B3>$,17)2/55/
@r5532
GCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCNCCAGAAGCCACGCCCGTTAGNGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGACATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGNCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATTGCTTTGATGATATCCCGTTTCAGAAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGNAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGT
+
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
@r5533
AAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGNGTATTTTAAATAAAAACATTAAGTTATGACGAA
+
D4:G6#!?'=2;7-,+;):02%@9=G@?FE!$%)5#;/5?2F00>0")B)589G:/G2@32:((47.(G8-C58>B0F:)?1$'+H',=FH/#+%5"+@2E>>*3G4
@r5534
CNGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCNGGTACCCGTACTGTCACCGTGACCGATGACCATNCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGG
+
!#'"*+$&((&!*$))*##'%)"""+($#%#'#&$$'!"""!*+)"((##&))))#+'+)$+&+)*'#'*!%+))#"!+&)*!(%)'*''*%$*"+#!'*+"))&!&%*)
@r5535
GCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCNGTTTTTCAGCGATCCNGATATGCATCCGCTGNATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCC
+
+.).@#)G71@:?+FED3?;GH?5=D9-H-F877<33D8:2912.D6<B-92,(6/2(,=;"!/@54D5&9$/71@2C,H5.G7-1G%ABDC)%=0+,G<H9&&+*/#F9E?=D=+G-<2,#-"@:C(!;?3AC/3G<G5;,G*"#HD=&90=$4=%./F(1%"9;&3>.D*C#!05F7!)';EFG:).,(636C-1/G9;/H.E1$E5E)?)+/$,8A(E$:8"E>(<@<5E
@r5536
NAGGNGATNGCACCNATCTTGCCCTNNAGTATTGNTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCGATGTCGGCTAATCGATTTGGCCATACTACTAAATNCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCNCAATTTTCACNATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTATAATCACCGCAATTTANTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATNAGTAGTATTGAACTTAACGGGGCNTCGTATTGTAGTTTTCCATATTTNGCTNTCTGC
+
"#)#"%''$*'%$$(%))%#!&(!(#")*##*&#!+')%#!()$&%+(%&!"#$)&)#+#+"+$)"!'#)")"&*)$"*!!%*'+%"$"%*"+%)('%("$)!#*+"(+')()!#(#!$'#$+&)&&&#!*()!+%*&+&&%!#$+(&+!&%"&'"%'$%$!)'"$+''$#$%$"+'(%!)$+(*'($(')*'$!'#$)&$+!')")*'!!'%$!""&'#(%)#"#(%#$*%$"+++$'%$!'+%"+!'(&*#'%)$!'"))"#%""*+")%$'''"&+"'!'+!#&*+($!))%!+&)$+""!&)+''&(!!%(!'$$"'$*$)!#!""(!)+()!""!'**#&'#))(+(+&$*!&!(*"+&'!#*($)%+'*"$)'%"%%(+#%)((+%&()'*"")")*"!)%$+$'%%$#$#+)+*#&($&'%''*&")"'+%"%(*(")*#(#$#"%+("((($&'%'&("&(&+)&&+$(*#!(#+%+$*#'$$*#"$!($$*%)''%+!&('%&%("*#'&(("$#'+"+%*$&'&''&$%)$'%*$(+#)(#%)&"+&**!'&*!$%*)&+%"(&"+%!!)&$'%$!#&+&+*'*%***%+$)*$"&%))+!#*%+#($#)$)$$#*)"&$&(!!)#+(*#%$+)+*$*'&($#&*#+!"#!!+%'%$&&'!!!*%&)"&!+($!*+#"!%"%*(#%()*$"%!)(#%($%'%)$#+'!!")$(%"'+)#!*%+)()%($+!*+($)%%*')#!#$)'%%!!!*&)))')&*&))%*$)")'!(##%+"%'(&
@r5537
CTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTNATAGATCNAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCNCGGTTGCCGCCGGGCGTTTTTTATTGGTCAGCATCGCAGCAAC
+
;-'=00*+'2F=4<C166+89,,!G0A;+-=.>0",?"E!>(/2&98''B=0AA?@,C8,+64;)>B!;3?,'F.*?,F0-7"*)HFE!8A:6$'(<=-&3*?!FA&;HC@?+/9%$F8@@+ED$+;*$<0()(F=81(4'9B:
@r5538
GTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATNCTTNGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACNGAGTAGACGAAAGTGATTGCGCCTACCCGGAAATTATCGTGAGNATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCNGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTTGTCGCGATAGATGATCGGGGATTCAGTANCATTCACGCCGGAAGTGAATTCAANCAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTACGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCC
+
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
@r5539
NNCNNNNNCNGANNNGNCNANTNTTNNNCTNNNNNNNCGNTCTNTCANCNCNGNACNNNTGNTCACCANGANNCNCGGNGNGCTNNCATTNCATCGNCGGNNATNNGCGNNANGTNTGCCTNNNCTNNCTNCANGNNNANAGN
+
!###!$$"$$$$!!"$#!#$!$$"#!$"$"#"$"#!!"$#""##$$$!"!"$$!$#"!"!$###$$"$!##$"$!##$"#"!$"$!$$!#!"#!!#"!#$!!$#!!##$#$#!$#!!##!#"#!""!!""!##$"!!"$"#!!
@r5540
NCTGACAGGAGNATCCAGATGGATGCACAAACACGCCGCCGNGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGAATGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACA
+
&(/1G"@9423:@FD66?"G93(:5E3.F*G-8G03!@*F+4D?6.7>E4?="FD@-=0!*=?%7?@:$-348H9?=0F573B6?6B#/B13:FF/G5F45>;8$<$'<8H::!1",6@#1*4$+@F9D'D",2/%A+3G1@65@4BD0A?2B.H6G*<2,'>#"*72?=)-&<69C#$.<8EE-0'A$.',>17%6GA@006)@"*85"4D=G>E8.(09<<<%$>@)").,!)+@D3$2)73=<#3HD6(16D!4BF!12'=##3A
@r5541
ACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGNTGTAAATGTTAANTTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGG
+
5"4C@,?7:>E<C'%%,?(/;>E07-BG63*F-5(#?34*5H5:65/33DA#>#&-H$(1H<$<&3#C6F)BH"+:7-0?,E(*0#;"<,AE9-37@H@/;>;@%C+
@r5542
ACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATC
+
=C:>52E(8#/---/D:&8=E?=ED<G>'7%C";84#1%)
@r5543
CATAGGTAAAGCGCCACGCTCCTTAATCTGCTNCAATGCCACAGCGTCNTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGTAAGCAGCTGG
+
*"3?63B@&GA<-'11/%.-29'44A;*66'<,>*6<4C*6F901&>=6D>>G,8*$;$'<-%72<#;*;)C&<8&-C73*A448&13<=2@8;,0*74('"8119*F8<3-2G70(D'$(
@r5544
CATCTGCGGATTCACTTCATGCTTCGGCTGGACATATCCCCGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCT
+
DC(0G,E>6,DF=-B+FH41CFCH=:=>/@?=!+C7D;?"1H+)='?2:&*$7?9E*$@21:>DA2H-/4D*)H7,>>=C<>;
@r5545
NTTCCNGGCTTTGGCTTTAGCCACTTCGGTTCATCAGCTCNGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCNTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATCTCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCNCAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACNNGTANCTATGAANACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACG
+
$*(*)#(*%*''+#!"$*#()*)!'%%'&$"$#+#+$)+)%&$"!()'!%(%&#$"((+$)''+')"'&%&#++%$$&'(!$"#$#"#%$#)*+'&"+!!%(+'#'$%*$)$(%&$(+#%')&)&+*('!%'&((!)%'"%+&$('"*)##"*!$+#%***))*(*&())%%)%%$$*)%%"*$&'#(*"('(('(*%!*%&"')#!'&!*$"&$!+%*")&$***%'"#!(&+'#&#*#)$$&$(#(#"$#&#+&&(("+)+(!%+(&+)!*'(%+'$"+('+'(+"%!%&"('+%(#!$&%**$'(*%'&%#'#&()%#%!%$*$"+"%+%#)(&*(!"(""%(%$%'*"%$&)#+")+#'+*')*'"(%#&&**&$)(&*+("%&$*$(+*$&()&+#**!!")%$'*"+#(*%''!+"')
@r5546
CGTATCGTTTCATCGGCGCGGGCAATGGNGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCTCAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCC
+
2=DE"9:9C-4901.A3:)?)%F</EE86>2D.=;"9>>9H$=50";.B>DA03</',=0&**$*1A.)!/24(><<20C0*A=?,#+F9$*<@(-/)1'97(21@G6F-,=@%>(9B!43=#B>!6(#"@,4D(>D:96&C>E>.0.5$&=4GD-73F+-5+-'"H,-F=B9,(4"66%0D$$#!.=D'68*2G":FB#6D&0H*;548*-!3;3)/A-6557<6/:%(/,47>>+5AE=;%70"H#%4'>B
@r5547
CTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCG
+
GH*<D3!69<;.(7.,G.)G?4,8)1534@#!EDE2@8A8@/0#=
@r5548
GCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGA
+
-=7C2BF)?$+@+0E4!9,:"4#1#D-E<26=$:;3$+-':"5$'
@r5549
CAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGNTTTGAATGACTTCCCCAATTATTGGAAAAGANTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAG
+
7+G9?FE;?H@1GGA;F9@7/$BB#9*2$*4"21H7>2&"(8=)%'2C#-4%B!(8/(&B&>@>>6G0&;E)F,DB3E)5FC?(2)+H)1?)63/B2+&G69)9+-3A6E,B"=**CCG9@A;25*9!"E&E0+$5H"<5@1%EGE
@r5550
ACTGGACTGAATTAGTTGCCAGCTNTGATCCATATANTATTGAGATAAAGNCAAGACCAATATCNAAGTAACTAGATAAGAGGAATCAATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCAATCGGATTTA
+
;0.#9:A+>G7+:#"$5(8',85(*&5@$B<5#/#/HA$6:=%.E%&')&B!@2H2HD;@BB8@7)&)?4D9(&C<2<29#<>BE-@'$,D&$6!!;;2H;9<>=C36?%$F"8CB>"!B<?C,F1;E/;FH-H=)#C8&%#<"<#=).%7$#&1+CB*$*3)1F34$+1=#)EE9C3G4%7?0;?6?#8='0B!%!70</1B)>8.-;120:0B6@+9BC'!0'/(5?@.1>?H7.4/4'
@r5551
CCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGNATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGNAACATTCACGCCGGAAGTGAATTCAAACAGGCNTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCG
+
64*E7F&!%/6,@1GE,@1($"!.4",*"B!!G!@-C9?,<$0,C?F/DB'%B=$'HA9'G(D@"!*FD4/,F2387&:5&&!4&8C&.%2;'D%76*G3#=5)F96C+2611($25=F(>#;-E52./@'?1A;F(%F%$-G#C/1CGAG07+?<<+?)D.0'+8*4+,"6@$B/<4%E!(G9?"%*G4$3460:>",B@D-BH5'>@&'+%1D>4D!5<-#-/=!%''GDG%9.GB4G$B2HAHG23D#<?A(.471--%B=HC;/;?*8(.+./*!+!+*9>/68#)'"+><(91E72C=5<<+GH8E3<B-C6<&)H+D&.@+=+'<2H;'&C,@%7GD-6?'5?@GD=(=2<361)G5@C+6@"C7*%.<?#""B></?(@%=<7E0>4E4.@+>'-E<7C"D8-H<&*.&2D>9,!E4>&*"E%7,+:(;1A=8872!33+;A&94#HEHC"$7E6G8"5G-8$
@r5552
AATATGGGAGAGAAAGNTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATNGACAAGGACATTTTTTTTCGTGAGCAATGGGTATA
+
E48.@?0+.1-#.B-7EBG5'./>F./>":$0+$3<,$7?+"'575<.7H7$%2E6HD=B>E4C,1->AG8B;26"E;B1'&./%F#110G=BD2,74,&4
@r5553
NNACGNCCCGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGTAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGGGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACAATCACCGTGAACGGCGTTGNTGCAGGNAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCNGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGTAAACCGAANCATTTNGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAATCGGCGCGTTGCTGGTGGCGATGTC
+
%#%(*'%+()*)#$)+)+%(+#!+'+)#!#&#*"&&()(%'"#!!$$$(#&%)+##&'%)%*)'&*!%'('&&&''"#&(($)"+)+''&(*#&('+)#)"+#")%")%"&"++'('$+$(!#!$$&%#&%*'$'&#(!)"&)##&"&&+"''%%'%&$)()%%+&*)"#!%'%"*!((+#$)!%&&)!$)%)'##$#!!!%"&'(!(+(&%%&!(!$&+%''"$*%!%"*)!&)'$+'+!&$"(+&(($'"$#&'&+(''(&**#'')))!%%!*'#(*!"$#"%'(&!$&)%*!$##%%'!)')(*$!'%$"()**!#!%$!&$(&%*$)!#(*+)"!%+#&$+&!')'#)%%*'!"*%$%%+%*)!&!%%($'#"#'&&&%%#$#+*#&!))%")"#&!'+*)+*$*$%%%("((("")'&!(&&&+"!")!%%!"$#)%&"%()#)&+%*$*++$#))+'$**#(%)&)+&)#++%$'##&#'#!&(*#&'(+)"+!""%**+!#))&(!$"'()&*+)%+!""!&"'(#*&'#"#"&%#)"#&"%($&+%$*(%++#%!$()!'+&'#&"*"$&)$$)!)(*#$"%&+'*
@r5554
ATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAACTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCA
+
H6A#C>250!!7C99'?@5+8%678949@'/A7#>!()?>4H=@99)$;<C<?B>>'!8)?#GE25D5)BF8)7=6!.D(3<!;<'CE,!?(EB;:2&:A4B*G4564DG#7FH=C7;:7087<E&/*&896&=<:@C-F)2)20*CA9+6#9<5@CH(&:-BC$>2,G/-:H(E@!@E-&:741=(,'9@&GH5<6;569B79H,&&H+:4*1D!CDF?D&,E5#7272!>A"B=&<6"E0#1>4F#A9F>A329)1<;G,A6/0C1H"@A+,&F="9<=EG#AH!C:$)2%<=+;+CD83!C!'32+7?D&95%!>;9"",/+@!*A.(;;D2.*!?<GB=$%B5:-##4$*(2@A5=4(84H2C,
@r5555
GGCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGNAAACGAAAGGGG
+
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
@r5556
NCTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATNCCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGGGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAATGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAC
+
'9&8H-,=:0';?F1D2$/0%#$!$72.":*1/3A&#%"7B8+?8)G''*!3.=0:F?,$26<'A,6/42:2>(F/=-!G1CGD9E"+,*B?#;68),1D"<*'2,%(6A;8:G9.)1A;B"FEEG!":*B<@9G<)2+A35:"(4*<#-<*H/">0?.66%/,"HBB"#'$A#'=:')D.6;&F+-+#(@6%1."16B&1@8D%H+9/7'>::1$2,G"@C1)9GAE0+A</*.353F25/BF14=-!C)E<FE&F'*:?'!0@<'#D-#.6.>$$1;*B!0('"0=%$/H/,$"#,*+D:E??G4A*"%'A5::+G)@.<'8(%;CBD/42E75@#)"?6.<4/G%:!:&8"=F./>G"@>(;5D(?(0+EF)*+G@#&%7+D<*C3%0H.C5/HE,D56>B(3:/&.;8GA)>,GG)*.-#88D96")#9(=82".AG
@r5557
TTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGNATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGNACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAA
+
&.C,&$?BBF@"'9FG9-A.%'C50:;,6$6/>E!,A)-!9#;B>3.E&+5H8$>B@@;3&90/9#'%$78(.58!BD*+7);0@5+(F.%)@(44"%'H)'1>.>0?$&56%%,$/H8<79H5B5/7!1@(:)+<+@GA7F2B"+H-A80B$HE%52C-H%D8E''0+)43:!74H21:9D",BG001?%72C39>CB45:,0'!3F))7,-5*%7/BH;08&28(G06;C9<?&E%CF,.(24<D0(%H398C*#CF3,$?>)8B-2(9"=,!GB$--"E%F+"9.B;9'AB#G5)61-=(%!&F6(G61(:87(>"1!1*)3=62DD'1=ED27)/G31"3%7*F$?<!D7$"#&$39*7!2"=@'2(B?E:3
@r5558
TAATCCGGANAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCGGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTG
+
.3B8"B&2+->D!,GF67$1'4D=.2<.>1=H6,=!3/5"2F9,1("!=?$<G+CC26HHD6;<G<9*;E4<=55!F.$E9%34869H0=55-)H8C@D43F&3B6@:9('1>E;;0?@3;1!'++=?7<1!141E,<3B,*6*?5/+2(,<#9B$73H<%,A1A0@G#$+&C)*3GED&73DC+493DF#9"EDABD4A%
@r5559
GACCATCACCGAGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCNCCCTGATGAAACGGCAGGCAGAACAGGCGCAGTCAGACAGCAA
+
+G>)'1*51C<?1:#9(&C#@42<-3D.<*8AA5)-(=@F!A"35'+A&)(9?=%1?A"0<-EFH;.'91$4'5@H$*137$F"=5-2(7'@-62?,7.14<1G,1GA,")CB$.@'D9@6G$<>+'12?B7'*H7D+1&(%&E<62*)>&13!)/"8',0C7FG,5$40:-HC%&0$A**%14-#$G@H=4*>C6*,E,!=-.H):6%?;2;,$-:.3D&?H#99?2E5F6,F>@F)?.D
@r5560
CCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCATCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGNCTGCGGGCGGTTTTGTCATTTANGGAGGGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCANACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATNCCAACATATCCNGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACNTANCGGTGGCTGGGTGACNGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGNGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAANAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCNGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGCCTTGGTGCGGCGGATGGGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGNGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAAC
+
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
@r5561
GTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCNGTGCGTTAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGACTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCACTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGNAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTNGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATNGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTANTAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTANTCCCGATGCTTTTNGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTAATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCG
+
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
@r5562
CNTGAATNAACAANCCGCGCCNTCNGGGTAACTCACGGGGTATCCATGNCCAATTCTGCGGCATCGAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCANGGCAGTTCCGGCTGTCGCCGGTATTATTCGGGTTGCTGATGCGCTTCGGGCGGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACNAACTGGTATCCCNGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCNACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAG
+
'))&%&$!%$#!&((&'("$*#%*!)+%&$++*!(&$*))!*"%+!$+%$%'#&+&&&+$%&!+&*$(#%%#)+&()**#""#&(#+#*"'$&$*&)$%&+&+$'!(#(#!%()%%%%&!(')+%+$"##!)"!#'(**%&+&("#&%+(+)"&+&""+!&%%(&*&%(%$)'*"+(""(!)''#'+%"*+%))&*!'#)#)!!(+%(*%$#(&"%'#!%)&'")!)+)"+&!)&+)%&"+'**#+#(*$*+)#&*&#""!!!&$+)'*'""++*))+'"))!&%%'!$#)'*$'#*+'*%($+#'+!&!"%(!#&)!$#&"$!'(+%!#*!*"&'*#'#$
@r5563
TGTCCACGCCGACGGAAACGGATGCCGCTGTTTTTCNGGGNCGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGNTAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGANAGAATCAGCTATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGNGGCTTCGTGGTAAGCACGNCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTNCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCAACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTNCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGNAACGGCCAGAATC
+
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
@r5564
TGNTNANCACTTTACGGGTCCTTTCCGGTGATCNGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGNTTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCNCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTNCTTGTGGTGGGTAACCGTCGTATNCCCGGCGCGTTNATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTNCCGCTGACCACGGCGTTTAAACAAAATNTTGNGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATANTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTT
+
$!'("$%%+(*"!#*!+)#&('+"(%(")+*&'&)))*#)$)+#'##)'$&+%*&+%$&*!&$"&%((&)&)%'+***!)$'%$&'!#*'!""$"$")&'**$#*%+*&''!"%&&!*&$&#+!&)%('(#!"$))$)+)+%*%(&'&#&&*)!+%%$##%!++!'"!*#)#(##'#$%'*&%*)"#$!%&&*++#)($+'$$+!''*+'$'+)"%+&"''%&$($*"+$&%'+%)!&(''+%&)+&("#)!)+"+*&$"&*)&&%+)#"#+&&+!("&%%+&$++)$&&#%%+$)"+&)!$)'+")(&''(&+#+)*)(#!$%'''*&''%*)%&%#$'#"(")!&**$#+''"!*'*(##*$')&%+&$*)#(()&!%(+*!(#"'+*+")"+%$%&!+&+)%%%"'%+*%!%"!"$!&&'%)%*'$$("*%%%+)!!"*'$&&"(&+'#((+&""%*$""!"'!+"**#&'$#'!(#++!+$++#"*!&%#%*#"!#!$*)+&*#'"*#!)*''##*(
@r5565
TANNNANCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTANGGAGCGTGGCGCTTTACCTATGATNGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGNTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTAGCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCNTGATAACGCCATTACCTCCAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTANTGACNTGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCAGATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGNGAGANGCTGATCACNATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACGCGCGCTTCCAGCGGA
+
%%(!$'$+*%'#')")&#&"#"$*+&(&!'&)"$)#+&++%"%$+"+*%))*(&)*$')'!!+*!%+(''*++'"%*!(*+!%'$#%+'"+"&$#"+'(+$!"'*##!%$'*($#&)!)#*))(!#+#!%&(#''(!!&#!(*+'+&#*!)!(+""%)&&")*&'')"''#%+*)"*%*&)%'*&%$$&)*!!'#!)&&#('!'"%'!(*)%&'+()($#(((&(+$!'!""#!((&!"%$#*!%(!)$+&&('%%*(&!'#'&"#!$&(!)%!()))("%&(&!#()#)'!*!!#!+*'+()$$$&&!+*$$!$&"##"")!*"'%#))!+%)*"("'&**$(+''($!(#+*!%#("*#"+%)('($(%('())+'**$$)#$!'&("('(*')(&"'&$'#)%++++('$''&!$$*%&"$(!''*'!+&(")$(%&$!##)'*!&$+*%(""*+($"'(#&!!((&$%(%%$%&!!!$$+*%&&"(#(##$%+*!(&'&+&+%&'#"%($'$&***!"(""*('')'%))$(*$%)!)('*+)!"**%%#('&!$(+++)""('!!*#*+)$*'(+'+($(!*+((*$!!)%'')*%!)*++'#))$#!!*+#+'!#%##)!)"+!*"&+(('))'%%))')(%!'%+*+""#)$('$#!#%!((((#$+)")$')'#+*&!&""(*&&!'+%+"&+$!(!+*()"$$(##(#!%$+(+&'#+)#('&*+"$&**)%"&)%'$$#!'$*$+$+#$%$+&!%""")+(+(%(#"##&"!+&%#(+*)*!$$("*+#&!%)+!!$(%&!"*"$)'!("%"(+"!))$++')"$&)&&)+)#*)%$'('*"&&%%&%'$'#*$*#"&+)"$(*('%%#%!#'+&!&!*+**!*)!((+$"&"!)*!+#"'"'$)"%)$#*&(+"'$'(#&&"*#%*%'((*))$%!$)&*''!&("&*'&!%#(%+(*(")')&%%")'&)+&"'#)"%++&)$%
@r5566
TTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGTTATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAANACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGNCAGANCGGTATGAGNCGGAATATATGCGTCACCTTCACCAA
+
$FA5:783"D7+*?A<9"0?-H'/D<"#D4H*!8(/D:3<&+B*'5;B0A:#09447B?=<"9H=@E-D;2::32+@2((E?4C*-#$2:>&,8)18.)-B'+<*=<.8D*B3<D<3<(EE>,B4C$92F!;>8GC.2@7-4G!;="E<!6>)E)G!*)(9%.#>?$.*1G&,;>;-?<!;3:8'4'&-*H@3$$6>&#AA2>F+.))7*"6!$#.4'7B4A!E=BA/"9<$1B#BC?<3@*$H&D45<0+>>E</0)&$@@79&2'.F"1<9G7'.1449'
@r5567
TANCCNTCATCGAGATCTTCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGNTTTGTTCAGAACGCTCGGTTGCCGCCGC
+
((#'%+$$!'+&""+!"*("*&*+)#"))**!*#))&(&"%+))&$+!!'#'()&)*"%)*+&)*++&*%!*)"))*!$**(!'')#($'!!()+('%++#'*#)$&$&%#&#!$!%)($$"++('%$&)"+'+$'"'!"#*#$"#$*#'#(%+'$"&((+&&
@r5568
GACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTANAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACA
+
8&7H14<H63+4!8(4-@AC45)D,(?FDC()**)<+<(B43B4=+8#+A'E?H#%#9%GE@'7!(&7(G96!B;86<'&<,3&3C.#G$3,.7BG%!09,:<(%=3G3%:&0-F&B6
@r5569
AATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGNTTCATCCCTATATCGACAAGGACATTTTTTTT
+
1*,#9D(%#;-9(?8F'-2%F"8FA<-B1<*#';7#0**88>46<.@)26!20''1=A,!G7H@67$C4<:>(77%.D9D&'+E7(&05G-H!:86ADDC=!!0053%G7#%(=5BD1$03"F7-/#+)B@
@r5570
NGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCC
+
#4&*A@B431H932H?81<912FEC,#83;$B!<>$-4@?>>D83#B#1=!8:&4B9.>3/<*DF
@r5571
GCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCANCGCTGGCGGCGTGANACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATANGTGCCGTCGTCGTTCTCNCGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCNGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCANGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGNTGGCAGCGTGATTTCACGGNCGAGCGTCAGCGTCCGGGTCTGGCT
+
17(83#DH/+;.09D7+;:GFGBF7B+9>=?)55215'&A6/5>(388=0H;*&#0+DFD887$9%894;%H@4A?61DG19C?3)=?H?35B=,='8$5CCB3/3'1#6(101.2*A$%G0"A>*8-F:(=G=;16""&@+@15'"G/1@:?/?@AE24;4'1DHC;<&583?!4@.>G<'.(+#2!,*/+97H:!+HG1%G#:+<*6'<7E1"*C=$C!.!,'H"2;=9,A;9,B,EC,(.E7;'C'?GF"7.6-:,?&<EEE='?;CD(0C<2E#4FF!08!4))+(:2"#4?$(";94$,+&#=#7*<4-'#&D+EF37BC.)-;0@*%*8A:E3HG/%(1D42B(:*7#G7C6%=>:&5(268,:/+:'!*8%A-#7=>H&2E0%/<D,(E0>E'8<+)'?>,B%H*0@9E30:/+%69(H+B+646BD--&,/?3>3A9>HFA/
@r5572
TCCTGGCATGACCAANGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTT
+
1#5?&;#FEH(C"B=1$,3%,H49:$$C8E!05#->:H!A824CG&)7-'A-&14)>A
@r5573
AAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATANGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATT
+
+"#+%%"##$+$$)+#'%&+##&!+$$(!!)"&+++&%$#'*(!#)'$($##$#+&)'%%!(#'""$"!*()#*"))%#*#&$"("&!%)%#')(+!#+(%$#!)"''$%**!(+("!*$'"#'$%!""%&&*"&'$*)&##'+'''"+)
@r5574
NAAATNNNNTNTGAAAAGANAGGATACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTGTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCACCAAAAAGCAGCTGNCTGACATTTTCGGTGCGAGTATCCGTACCNTTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGNACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGANGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCATAGGAACT
+
&&*%*#%"##)&%%#)*%((%'&($+%&#!*#*"(!)&""!#+*$&*)%+**'!#)"+(*"'+%&#((+%+*)$)&####$%$%"""%%)($$"*)*!$+%&$$('%#)(('(!''!''("!*$*+"#*)"(%$'+)%%$!*$*%"&$+(&+$%'((*(*%!#(**)+'&$)$$*)''"%+*%!$*!))''+&+++'+()#)&(!"#%#+***#'*+(!!")()#&*+)'#*"#""+!&+*)'((%!!(%%(&)&*(*$$($!!*$)%%*%)&!(&"$'&)$'!'&+*$%##*+&*!#!*&"&!$(!+#%%)+(!%(#))*)(""$$+(((!&"'*(&&'##*$""**+$$)#&!#"+)!++!$'&)$$$#"#&#(%*)$+$'%(%(*+++!")
@r5575
ATTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACGCAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGANTGAAAGTGTGGATGCAGCCCTGTTGCC
+
!=(39<.'A/H6&.(#32):/FD*!+(>9BF&'&*F(+:=&(HE1D5!6?>=)#C#;9)+:CF4<.F*$E3EE;(+3"16'92:046A9*02!,,>-EH.*=C8?A&+'-D>078G!.A8>"&E5F#;=#(*:B77$8FGGC-(D7(@9732:F!75<@7B5',&5")1+3'G%)>D98'68#&%$@:"="<0"7>&HA;3@8,)9#18(=B/G@25$3.2&."=DGC1-,/6HG@2A%.1H2
@r5576
GGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGNGTGCGTCGCTGCCATTTGTCGGTNTACCTNTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTG
+
44*:?<)1<6),'0'=G*CF?85%)6"-B'E8B8B"F>DA9D$9G8;0/A66)E7-#,@&7G(/B21#>7G9(2F4';F=5H!8:;("*8#F21DG19D".5:1F/CH?F18)A&#<#&GAF0#4C8>:H0+"&E&//'&'02.-&;"!)-2+?,/*5,C#D")!&"?$0*F<'4,5<1G8',*"@&,B"%0(&84:*$0BF130B#2&77E?+@D*<*EC$$0@)9F1A78B!."CD9F
@r5577
GTGTTACCACTACCCCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATANACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACNANACGNCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAACATCGAAGTTACGAACAANAAANCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGC
+
53B.0F"2/E*<-'6"D!48BF;8/4*0%&>-B'87)&3(BA46#ED!*(&B5"A7?7?7:A?;)4HF,D-&8C255D%*+$H.AB;!/A:>!<&2*<1&4&,B1@0-)68A2H?>"<1-+22;1.FD;0(0.1()84,9@./+;%)D'8*7"</C$>;5@A!-*84(5?22!*D67B/C1=H)D+G?<,B,)AB32=4B0-5.C*30@,*E>1E:3AD,*,6A/5?5270$/C&*#%D=%6#&.C4-H*$F59),666%-2%E9C@*BEAH*<$3!9"@E+B;"@9/8FD03:"DF#G'G"*D=H=%-<G1#EFA86%D&B5*+(40,>CC$E>!2C03
@r5578
GGCTGANTANGNATGTCGCTAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGCTTCNTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAANACGCCTCGAGTGAAGCGTTTTTGNTATGCGGTAAAACCGCACTCAGGCGGCCTNGATAGACATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCATCATTCCAGTNGAACTCACACACAACACCATATGCANTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACATCATTTAATACAGAGCCGTGTTTATTGAG
+
*"&#"("&%"'!)&''*'&+#""&((!(*#'"%##)'*)'%"+(+$*(()$+#'#''")+((!$&$%%)*"++"$+*$"()&&"#"+*#%)%(((#+(#'$$'#"'#+(#(+"!!#++*+!(%++("##(+&'%&($)+&)$$*+*#)$$)&$""')!(##*%((*!&&*&!!#"'#)#(""#)&!$&##"&+*+(#''"%#('$)"&$&+*'(&)('&'+(+)"!%*%%&#"*&*%!("))**")(%$%*!)*%"'*)#%"+$(!&#(('!"%%(*%(#!$"(%#%)&()*(&!%+"))!)*$(($$&$#$%(+#((*&+&!*%+&'+*')*"(!+$("#!$$#")("&&!+&!+&'$&*''%$#'!()#"&!+"%&(&)&%)&#))*+)&*%*")%%&%+&'*$))$'+)$)$(*
@r5579
TAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGGCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGC
+
G&5=F1B*8H)2$0C4GH4G/8=?7E:7B&+<2!<:$D++?)$2#'(-.+F.7971!!>C1C(G>.90$!$:08"8G9152"E6##.@F(E0!1C347$:%%4$3<,C&+*)%=5(D"46;@A6FAH-,9'*;99&82"):'<35',F:"H9-?.>EB4
@r5580
CCAGAATCACTATCTGGATAATCTNGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACNATATTCCTGAACAACTGAGCAAACGAGTGAGGTACACCGACAAATNGCAGCGACGCANACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATNTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAATTACAGGAGACTCTGNCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGAGTATTCCAGATTGTCCTGGGGGC
+
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
@r5581
GGCCAGACNGGCACACTGATTCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCGTCGCGAGTTTTGAATGGTTCGAGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTAGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCNAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACNGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGC
+
D'6C&,.&%'AFE45:<1G*524.-%/$32BFH8(,(.A,81.!8@&09!EFB.A*%-5E@12D;:2$!-1"757-8F8DG.@E&C4@,F**BDEE&2G;7EA(5">+,7AD@=!F>1.D91@2.'1(CB3B<AB261!9;0+62!(<435*<D/E&0CF/1*),E;AE62=*6*-9);#--:'7#74=G%;,E;9A?!!4<:+3)/>,;4F7410;+8*E>676-H0$>,<>(*5B.#2-&>>CCF'5B=2"'E)2&G,B8279.D@&7+B"-"0?4F/0C3B&*48F)C6&9$;F0/D>$C/=/?"D2(GH*%#7/6-&"35@&)%>4F1AF4&7@.(B"'.%HB-B&%)32(/3>%'G@H#<$(,G.G=:'G)&!%%@E",3;,2H>EF/;B"'C+?**?$G$#):FD8D/.;'"-;+22,2>C)>5G:/4*9D(?#?8H=GBB(DF38(96(E0C3&?5"36'E,0+9A4*A$7)F
@r5582
NTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCANGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGG
+
"CCF6F5$.HF'/%9E?<;!+E*').-!=A-%80?<!*E6BD?H@/?3#HB$H=D3&BH9)4?3#-++73F"888=0>3.!-51),$)%%'-+8$"HE)AA!D&AGE:DG,F"EDA$BB:="<1<HA1(CC<0?F=.G9C>>9,@0E/#FB@!;,$%/&10AE%C)51?+1,=*8-)-E::)!+6<+/7FE;D,&38'(/%(9A:6D9%#)./<B8?&<F&8(3'4F#<8585<(>&&77?F9"#7C%A;$E0#/?5#$1FD/0B4!);/+*C9>6/DC56@?9B1A
@r5583
TAAATGATGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACANCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGCGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACTATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATTGACATNCTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTNTGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATTAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCNCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACANTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCANTACCAGCAGCNCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCC
+
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
@r5584
ACACTACACAAANCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGNGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGGCAGGGCTGTGGACATAGTTAATCCGGGATTACNATGACGATTCATCGCACCTGACATACATTAATANATATTAACAATATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATANGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTGTCTGGAATTGGGCAGAA
+
0:'+'0/!;>:*(2.<5;),)0$6)C04C?E>+D!"D6BG)9,7:,DG?<C=<)%;(>H7C.+%#5E*GE+0$,8*&DB,;!+-,F>*8>0H)!5C*!>;.B5GC-+*;/HG5&)EE;,;H*;8(30?=H5FF%-&:<B&/5'DG53:!?,>3'%B:$4CGG9/G<0";8"C-)703/7;=4;H5"!=2.$746!=&:-+4F*3&,4B6$(%D&)CD:%>>/>@;E62.1(4<FF:9(:2>(=C%!>E%.#H<435&8!H:<%:&:4-H=><.;#/"BB(E!A*E8@(:454-14+H.D@3>5B:/3.)C$54!7.7&&9/0:33-')!"6G,E,+%*"759A@6.G3(B+;5<3D:?%3B93*G1??%EF8$/66*FA<D2$4</G4AH230,)0%;8=/&00>F?&D/!45</723H'?B57-:-,;$A**10HG6459/D/,>E*096=386F7F---
@r5585
AGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTGCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGNCCGGAGTTCTGCCAGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGANTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCNTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGG
+
=DB&9.$A;7G:%B?-C1G15)&.2#GF$48B?1CH-5A>;:9;>$2#D79")?.<)H8#G>&9E6?B-&=0H$44&"AA:42'5A?1)>0?(D?&2CE>C:),%*:#%"<#'19:!F/5)7/@%/@>EE""6EE3<)H;6@F0<>39$4(;B:F79(DF7A32>H(-4%7!36$F8&(.B17E"118F454-!.@6&D2,)"',GG*GE"$3FB6'>-$=$)7B.&'/*=47@1>*/1#='>1C8!'HBCF9+1;!/B0&=9D30H"G8B-*(,*B#>(D6(G3B/7<">"%/#B)./-6!$);=&=36-436>4C44D@:AG+'.HC?D$60F1;258C9@'F&3.(%BE8F8G2@-3<#&48H$6:+12/A.E&;HF/;"B3>?/@E>4A><>@(;2>E56%EA),:AF;!'->;'7->?0,7G<?9*"%,@-B2&'+42#4(+9%&805
@r5586
CAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGNATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGNACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATNTCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCTCNGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTATTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGANCTTACAACCGCTCAGGCATTTGCTGNATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCANGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCTGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATNCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGNGTGGGGCGCGTACTGGTGCCTNTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATAC
+
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
@r5587
GGGGCGGCTTCAAGCGCAAGANGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCNGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAG
+
'@FA2C."C4!H3-2A!8=<$>/%0G.$@G<C67$')A8?,(,5!41E.0-3.>>"7757*DC#5)FC@A8183@H%&C51EH+*5&F0@&96B6*'&2>&"/-)HGEA$A2B1'367*$:A=:2*#A#%'14?9%84&150D!-=EA(FA,5*?B%CD536B'?#-"-G#E4/""
@r5588
GACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGNGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAAC
+
*3(!":C!@FGE"@?E,)(>A6&-C&3:*:F.0(0)>,=>51"17+0>-3H@,+?7"8&)H)8EB36G85@E6<2.C86&!<<6C5DE6;""-AD,CF<:F!9<3',1FA2&=H4>.>42''?;<2DB0C>>37=9(;DA(5G,%:##"E4H%'@H,E"C1GHGD?104+H=,B);&>F-,09$F6H=.6'#?&C1EE5)@*&'@C4=9/09$H9@E6(46&)>*A:.445#DC+-DA:#.++<
@r5589
CCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGANAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTATTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTNCCGCGAGGTTGAAGCGGCAT
+
.(&=/B-H>@G>"B221""-C@(:F<AAGAE0&<.H(=8#=A(A?H74FB'G$F5F7>@":E-=36C"=5$E4$9D#BGFB,%&CDF'$'FB3#$B%0;2-:;=>:,)#:1(.>.)B3=+'2/"GC*<H7,,=6"3'<+&)@<<@$<4B),><=>C$#1'2'-CBB@%.,@-#1D+.#>4<:"@>/8D*?&08.H:=7!,5->>/A9F?#B.'G!214($'5(:7*5)4D+3=)%:&B39:AC%+1)(3E/CD=2.@H8G)@+@GB/*2!8$320!@D=?G2!05!EA092,+$:'9:H+3<.$::H=0*/'522B"B3$,F&9%?8+<3!.D
@r5590
CCGATCCGACGCATCTGNTCACGGTCAAAGTTAACCATCAGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGNTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCCAGTTGGGTCCACTTATCGCGGATTTNGGCCGGGCTCAGCACGTTACCGNACCAGAAGTTGTCCTGGCNTGCCCAGCGGAACAGCACA
+
"0;A(AE&)'$-<'6E@9.!8)F22G'+34'(?=@F7EDF2#H,BC/*&#*D4>-D"*4?'88C:&6;$<,%>/.6/<<;4@$&/BHEHD+7:.)1C/:)&G61*B%<DDCCG!"+$-=?BB*11A;'E1B1%;4/DE?1G+*5BE,22@3B22B+#"39(6'=+"?@%C$<B-;)!?3?2=G+1HB'.&CC1<!5'!#7C@98!=':$H(D9(<F--&A#'>"-'@7+)9%1D#===@
@r5591
CATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTT
+
/8*H"#B;>E8/H*A@$5(03,@4(F=D:332G@1+854;F6#1*@*5#C2",::1#/'<@,.3%H@/F0,AD&B9!=(@&E@5HBGC;6>G))F(2%);3<>@=>)5F+:#45*18#4>+B4D*;71(24F&;)"E%4GD---$.CE.!$H!3A>9&D375*A);!:8C6@5;-
@r5592
TTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGT
+
H.AH;2C+*3DHHDA#47&0"2+B</E.=+/)7'"&;(4!B:$1<$G@--F;&@/*%,A<9B=%8FE9;E0&2.9,&8$3+6".5(5%9<?.?%,65G),#H9'!)>EC4$H$9#/A5A(;<,5
@r5593
GTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGCAGTACGGTCNGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGNCGCTGAATGATTTTCTCTGTGCCATGACGGANGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTNAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGNTTGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGACGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAANTCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCNTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAA
+
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
@r5594
GNACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGANGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAANTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAA
+
(-(/7@*83<DB+7+!'F;G+95;'76.2?3='FA3@6!,!!4E6,:##5&"'!H(9,#2*)#*,;:F90E%+5G%0=<&;D;:7:!G4*6H=,8A'8@7+*)8--0/61*="*6%@0;<5H)-:#9CHH82)00E47=9;/3891%E=&G):9--"+=6'E$(>)ED0.@G(.#/83"7B-/%9BG'*B->H<)!ED0A(A-'@5AF*-3<'F9E(
@r5595
GCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTCAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCNNCCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTAAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGG
+
H?.8'DDE!A!.G&<9-+=*3;5DGH!)(6&,>*:*!6%#@D!E9A*3B:"&.7B9H3=+<E3<)3@B>%&;3'.8FH@%$14/D-%:+6&2(;#GFD-2>#/278@@H$.+3783"$9'1</&@6:F2<'88>%8;(G6<75>B<8'C18(A;-:E:%F;&"(4A70*+.B<69$':&H'@@?:%C97$(>09'G3G6'@+.0?8"A/D9-H2F6FE..*G#!)4=*B%-B2A?-H%*0")30C#77-H9@,26"5:9+CBG@$1*"=',8-$%<%"<3%"84F).B!H/".*'6>/%D';G?@3$3>)!58;$*,FA=35D)4G*96*/,E,(73,4/5(A502+85-;(>13H@E=$D6B7G:*0>+B0984.!,6)H@(($<CHHF/;3$6$<E(,54(G1-A*CE>H%%?BEB1@.&)$&61-/*'C'+:&A!7HA8##;:..5"(C@0:,=5E":%E,EB'(@>*9>=
@r5596
CTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCNGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGA
+
>BB#+7/,A*4D@;3#FG5.F);H!%?@='1=:$78D+E-.2.93G*)!)7G:D8#.45/%A5D@/)$$B/)7DD?;#1/7-#FE5%*A;)3963""?H8@E.3BGAA,79CB6?3:&+;?/?A&CF",25$"09"+-"7",55E9C-:>>).?,3=(6/>FFGH*4"=:97#5)70*=E.B,E<'%+6BB@&>)/+8(1H+8&$-H#/#<>$>8.$FD*.!!,5-B-7@,
@r5597
NAATAAGCCCATAGANAGCTTCGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGNGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGACGTTTGACNTCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAAGCACCTTGCGNTAATGCTCTGTTACAGGTCACTAATACNATCTAAGTAGTTGATTCATAGTGACT
+
#'(*'$)('"(*'()**'$'$+*!!%+#'$$!!$"*$)#++$"*'#()$('&+&%$*%"!*#')!$!))#)+#)"!&#")(()"!'"(!'!!&*(%(%#&""#"$+(#+&()))&&$&*$!$"'&*)+$!!)++%"(**''+)++&$$"(&)%)*$!!&&'++#%)#$(&*)!*(#!$)$"))*'&&#)%&+%&*"+%!%+#!"+%"$!"#%&#++$)%*#(#*)(+%*)'&(()*$((&*#!'(*'%&"'&('&&""#)(+#%%(*'$$$!(#"%)"*!$')%&%*%"'"&#&+!'*#!(#%'$$+()&+&(+$"$)!#$'*&'"(""))(#&#(+("#+")&'&)+!*((+#')%+!%(
@r5598
TTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGATGATGCCAGAAAAACATGACCTGTTGGCCGNCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTG
+
2<F7G<FC6-#)0,!A)7*4F5@@18H!%$87659-:5"=+A#*:$*;EAE,2H!$B.<0"+??E0B+>4BF-2/4/%H2=>.*,H(!78@8!7*&7.9;!755B(%<'1.><C'546
@r5599
TTNTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAANATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCGTTAATGGCTTGGGCTAAAAATNCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAANTGAGANTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACNAATAAACAATCCAATGGGTGACGATGTTATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATNCAAAACCTTACAGAAGAGCAATCTATGGTTNTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAGGGTCTATCGGATTTAGTNCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTNCATTGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCACCTAATCCGGAATCGCACTTACGGCCAATGCTTCCTTTCGTAACACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAANAGCGTCACCTTCATGNCGGTCAGTGCGTCCTGCTGGTGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGANGGTTATCNGNATGTTTTTTATATGAATTTATTCTTTGCAGGGGGGCATTGTNTGGTAGGTNAGAGATCTGAATTGCTATGTTTAGTGNGTTGTANCTATNTATTTTTCAATAAATACAATTGGTTATNTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCANGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCGCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAA
+
&'!*(+$!(!$"!$$*)*&)%"&*'$$'%%$&''$$&&*&)$"#'$#''($)&#*&'**('&&(+"**!'&+'"$!##++**%*$%)++(&!(*''$#*#+$#$#++'('$"*&*(%#"*"'"()#*%%%#&$!")!&#&%+*+'+!()()'$"(#$(&%%$*%#%"+&"''#'*'"!**$#+(&!+)%'%+$#+$'+'#!(#&*)$#*"$+"&'!*)"$&$+"%))$'"+%!''%%*#"(##&*+'&!)*%!((#)*"")#"*%!'#$'$!'$$+*+'$$+"*'#)&"$"$%)))"*"$*#$*!&))($!+)'$+)%#'"$'"%!('!#)+(!"++"'''+!+'#&&&$*++&%*%"&(+$&%$!&'(##%&*%%"!&%*&!&)**&&))%$#((!'$)&(%$("!#&"&"(!*(&)'$(%*$!*"+++*&$%*%#)&'+$&*)$))!*+#(&'"#+#!*'%"#'+)*%*)*#'&&%"%))&(''$#&''(!!%(&')#"&$+%*"'&$$%#*&!*'%('$&"*(+*"+*"#$!"*(%%%%&+"#*+%"$)*'*(##$(*&'%'#$"'%+&"('*('%($"&$$+%"%#!('($*%#+"&('!%+(%+*"&"$#%'$!"(&#+'++*!&*+&#&!%)+""$'&'&(')*'("$'#%"%*#"&&$(#*#"+!#$#$"'#*')#'$#+($!())&#+"('**$!"'$)#+%)!'('&''#(*!!##&!**!+($$+$'+*&%")*!'+%%*&!&*)!(((!)!!*"*)"!%(!'$*&(!"+(#(*&'"!)#)"$+**$'#$$!$!'#"'))($(+$$#!%'#&("$%$!%""#%+*(%'"$%)))$''"+'&!!!"*()"*&"()#$)%('+##+%&+%&%$)*#"$)(**')*)+&(&*!%&%$"$(!)+)(*&)!!'#*#(+#*'(%)&$*(%&&&)))+!*!!*%"*'##*'!'$&('!''+""+%!$!)++!%"+!''&'&'&)%!)+%'"+**&"!+'$))!'%!*+!")$+!&)#*$+!('%$#&"++!""'%&(+*(&*$&'$'#)!(#"%#"**%#'"'*!(#''))%"&%%*"'((+!)&"&(#%"++%%+''&)$+!+*%$"!*$"!#"(%%!+'#"*#()$&++)$(#!#$))$##!+&"((#)%'$++"++&&("$+&&&('$)(#($!!*+$#"$$#&+*'(*!"*!((%##()%*!++(%)#'&!!)&*$&'*"+"%)+&'&)%(&*"'&#&)"+)#!+!#$%+')'&'+#)+!'+&"$(&)*(+)'&"+*&"*&!&!++&&!$)+*%$'!*+%"*+%$#&!*(+%($$&$(%"!'%)!"!"'%%#*)")*!#*(%&&'#'&$*)%"(&')**'%()''+(#"!'*)!!#)!%(*(+%)+""&+&!&"&+)&#%*+)&%"''*!'!*$#+&$"$#$*)+(&'&'$+++*))!!+*)%*++"!++**%(!$"('&%!")$&*%%*#!!*"(&+!(&%((%$+$!'+!$""+$%)'"%%)!%#$!+&"'&)**+("+#)""!%"$+)&$)*#&*!*+*"&+'**&%'#&''#)#!#()%%#"!+!#!'$(%"!$("!))*!'+%!%*%*('#+&$&'*$&&+)("#$+'#*"!#%+'$$**'*'"+()#"(&$+!$*$(#!)%&%%'%*)!*"'&&&#%#'%$&+$&+#'!(#!*+)''%&(")%$(!&#&+*%)('#$#%!(*$!!''!)!+($#)&*&&!#'&('$##+)'%)*(((*'&+'!+!$)%+%*'*"+%+#'#!)!%$#"+'$+!%$"(&**%"+%$+*!#')&+&!"#)+)"$"$&!'*'"!$$(!$)*%&*$#+'$'(*%#+")!%%
@r5600
NNACATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCNGGCNACGCGTTATNTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCNGGGAGGGGAATATCAGAAGTGGAACGNCACAGCCTGGGTGAAGGATACGGAAGCAAAAAAACTGTNCCGGATCCGGGAGGCGGAAGAAACATAAAAAAGCCTGATGCAGCTAGCCTGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAA
+
##!++"*'*(!'$"(%#"'#!"$*++))'(&*)#%!(#$+##%+)#*&&%)))&*&")'(')(*"!&#$!+"""+"#%$(*%(*""*')%)$*##"!**$")+$+"(!+*(+*""#$#(&*!%+*!(&")###!))#'%'")''%%+&&(+"+'"##++%'$$'+%'+&*(+**$!#$'())')!'(#!)#!)*&"&+()#!'&)&#(#(!!#(('+!&%!*"#)!'#!)$)*$#)'(%++))!#'!#('**++&(++&*'*!$##%#($!)$!&"+!+"&&++((&*&'%#%")"'#&+%"'!(')&#+#(''#*"))"+%$)'%))$!&))$$!#"##*(#!!$(!)!#+("$#'%&)"')!))$""!)+#%%$+#'%("#)&))!$+'+#$%&!$#+)"+(&&&*)&*$#%%!"#'*%+"*
@r5601
GGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATAACTATGCCGGTATCAGCACNGGTGG
+
935C1"<@7+E*;,1#14HC'!(!6E06.D),@9A?#$?2/G:<>;7HE>=C'@;+=60++;!,G"3**H#/.F%9;;,=#F15+0H!>5B*:;/(/!A@G)2))D*@:$/.*/,'.,C4$01197=)%#+F<C"<;
@r5602
CCTTTCCCGATTAANAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCATAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTNCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAANAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGG
+
1F=HB"@2@G)B')C=H-8B8"5'A*9?02&:H;&-0")'EF<35:?CE@7:(%8&)1F60%51@D,!D->A60339+<1'6;-;D#)>C-A4<:72,9F?($>3>8*G$'$/".=.5>1$G'B$0!090#*C8G=4!8B?6%#><04C<>0)(8G,65-&4@(',.B:@DHA7?E;590HFE!/,DG$A&7%=$43:?,,&=5,B5(450-/',&>:$!#8+1/2,"5@*E('$64!/*F*#*/0-)@92B''5!&9)*5,"/1=,H4'=:E&*;H@,##"#*8;)%%5*7G4B*".5#<*/
@r5603
TGNTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACANCAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTNAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGNTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGCTGGCCTGTATAGCTTCAGTGATTGCGATTCGNCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGNCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGNAATATCCTGCATTCCCGAACCCATCGACGNACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTNAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGNCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTCATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATNAATCTCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGT
+
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
@r5604
NTACCGCCTCGTNCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACNATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGCCAGTCCGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAA
+
0=)%H5*=A34>/&#0-4;H$'/'@'4)=&=31)B':(>D8!$B74<D)?$=D0/("5GGFBH55'E--D6%%6'.C#G5<771$C",'3DDE<22#%F1*28@>:;3?G574D?&9,1#D0<F-<7'.792'A36<66#D%%F%$:(3*0"!633-8(=&=9?-<29<(E/';#E2DB=6($%DF%4*>77%:&4=,=:1%;".!GC&$?E6;?EC1?3=7F9"@*0375?H=098-3G1<
@r5605
TGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGC
+
A*#H2?"$1>F#&:=&=-GH:;)*5G)+(@'9F#6"4''4@@,8AF787;0=/3!"<%,#+A4/"";:52!7*'#7)9?*+798$"*H*$560*'#)*8&.
@r5606
GATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTNATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTGCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGNTATCCGTCAGGCAATCGACCGTTGCAGCAATATCTAGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGACCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGNCTGNCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATCCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGANAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGAT
+
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
@r5607
TACAGCGCCGTACCAAGATACCGCGTGCTGGTTTCAACCTGTNTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCG
+
;F2+,6'GF)4D"-3!+,"'.B?E:416!6:"?G27%#C$B8)5F(5?2@*+(."B#=:8":A=>#9/,*F!;)46'*@7)F*8+<#16C*#D4
@r5608
TNGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGNCGGA
+
AA*3C29%%H2/?<&G;.-7)=?B1(:((545B:==*8-A$::-H<>??D;!.B>C=H=C%*"1
@r5609
GCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGNCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAAT
+
:#&EA3E*5'?(/C8DA4=/,>/)0-&B,93?A8+25-"31(,;):(@423$8)F?3E""<'B2!:+<C5+&,76"?2FG+.'!&*8=E%,?'($0$2-*3/A8?:?AC-A+3B6>!
@r5610
CAGCGTGGTGCTCTGCCCTTTCACCACNGAGGTGCTGGCAGGCNTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCTACATTGGTGACNTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACANATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTNCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATNTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCACAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGT
+
,0;0((=@1%:1-)5*>1G?9B:':(,1"+8H7100<#H*1:794"+/<8?(*.H>GF2!:F!*8@%&DAC>$<@A"**0/5-+%G$;+H?*0.(A571+E'.59(,,,H9)!@>4D>9%D63468,D4HF735(4"E-A1E?&<*F9B%8""E.+;$A#20'*H.*;@:"8?*2!EG?8$"?57@?9/</*3&:G!)$9'9'G3$7='@(#A2F7B)#>?*#AG@9<,;"72#>%B.%35FB6F+.=:BE6%D7$,1.2*;*@!5FC*7@*C-<HAB$"+"8DHAEH.!4<EA(/$<##?<=%4$H#-A1$.-D03>A!8+2B633+105.)6B<$<,E'8/%&.$H,G<0F'6(1*>H8&@/(&/1&.B9.&H*5/70:C.6#%,"/7"002D6$&%"G?HDG/!!*70=G
@r5611
TCTGCGCGTTCACGTCCGGATGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTNGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTANGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGT
+
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
@r5612
CTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTNAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTNCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATC
+
:9=0?4,!.;1*$(8A-404;F-31>3:*?2,>1A5.')+8;$%9;"./&=!H4.$!<H!>@3:,("=12:!E0<5="F-=0D"$?D4C2F!":@6*9/"03#<1,'?(87#;AC1F(:#G6,%.2'&&G!)AE8<>)!*?)!E.G48+52;&BA7(B+34'G.0GFD.%D,$<*C"D!76=3A:EAA+'1/6!&-A/EH6/#=B#%!!7H#61>179E3&04=?A9=;+<+/3(AFF&459&#A$D33D.58=G(H4=)#H?D&-A/5F".*"6,9@@-??*D%("/"?C,.@A??B$<0'+C'!;,9<'(+:6:;G?/"H:A?5C'?,/##=,C@@F8-('F;=C(A*+D/#.>BE5;$=EH0"8,5@&'!@D+F<?**-(;(H@;H->?9*9>8<?H=<%#8,A&D<)>,!!190=6=B3$-3=%H@&=E;7
@r5613
AACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTGCCCCTCTAAGTAATGAGGTGTTTAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTANGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGG
+
??,?(<;$-8))6%#GB';1H!=*F.1C(.F8H0F:B(>$%56':7@D:FG"A>.490?">C%9D2=)&8$7;!54'-%@B3;8DF@)--&97GHC)'.895FG-*E,)C-0@@37>,4H.0*?'D-2)F4BC?34&DB=@B.A4A4F#((4%*?@02:?C77.A+3>!<,9+,;&%52@/2.2"(+60G-H18A>)4HB9EFD5*
@r5614
GATGAAGGGTAAAGTTAAAAGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGNCAGCCTCCGGCCAGAGCACATCCTTATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGC
+
7F#04=03*7,.$:;F&@,;D13,!"'AFF*@2.C(-)"6#3:';!1,%!2B78H"&".=)4?)DC-9)6@2?.G><<2*)GDD"-1.=F(CA5D=B@>2=GE-(4DH%%E4'5B@:'?9E!)D+=-"8#)GB(#(G(&+'%/3,',%73,&<>=';0;B%(D,0-;+7<FF'B-.
@r5615
CATGGTGAAAAATGCGATATCGGNAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCCCTTATTCATTAATAGATAANAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATNAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATNGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCGGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAANTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGNAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAATGGATATTTNCGATCGCTTGTTTCAGTTTCGTTTAGTGCANTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGAAGATAAATTCACNAAATTGTTTTATGTCAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGNNGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCNGCTTTTTTACGAACATTAAGCGACTTNCTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTNGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATAN
+
D7:)C7+.(:,G9F-69+%C0G"=?5"1@3?F(@##H#B-"/EA7@1)@*:+"?H#0:'&EH'5'?'?9&/@$(EC+E-,9$&;=8585B6@E+5C.-&ED+@:<-.73F#DE679)G6,5(0B%F"@80'5F2).=+@9:D=D8E2;!E1+"@-'FD'B<1.3*@>!<(1C;))#&H99%3=@+.53&2>?C"7<,#F7?;BAA167'B@4/"A:'15E";>!,%7%1D#+HD1'-H:!-F8>-!B%47FC"(C47G9+&!-/81%&!*1;!#<+<4+0?E$8)@:5"'872481-(0:?#*4!3./&$G>C;10GD*=2/>3=3*/D(!(F>#!1%FABE!E>$A/#7!0A7;,7*:25+)"7E@)<B&@->=060B958=@'DF8'>1B2@C58*!0(=@AH%9@$$=5DH)=4++7A29%?/=HC218112?#C7.;)+C14)$%>!F>738"+DD'F.4H9H8(2@,%+<1@;/G<#):%9/(,!)-HC"8287,.:(./4)-1A(.34,(26$1AA%C.B"C6<5=1+1*%1491?87+GCF)F-A+"%@-C+F2%E1,%*.#8%'0$&27:8A?F83<.C9<%+-34#,2BB&),=&75HD28@E1)0%C*GG,F+8;>.5!))F@>'(C8246%/CC:<%+H)E07$0$B)&2-64-)1'.:+.GF4AHG7(>$:2A&'19B<@8F==H9.07H7!'')$>/4H<#E5)1.);<:14$B16H4@.-1<:+2B-A0,<>=*CC8$:5?C-<C!/47$.2+2E30!C+;*!%/9?-C9B1350,$3A*A,((<=!337G"D$0-.1+#2.+F-B&#GD':/#.=,D12C<G7&!:2%;E:A-'$)!H<A<7=*.1?A&01+7%6;3;/"&B=B0(B524=5+9?5#1:*(FD3('7:1(7-64!1;),:',;2$G"!>/E2:"@&.,E0/C<!>=,77",74)8-67D(7>B6"0A.E'GB,/+6;,$C*8C",,5$%#=5&5>F/<G(0-@,H3,8'DB3-"A38D,H)64&???G8+649C,5=-9G9,70&2+;??%558(!-!@-2*-1;04%&D:B9'!-0(6(&+A8CB<)?,@$)%%E#(8(2(0:"$1?$$@8"078582D.5'2EA;5&;D,EC);7'6@(/E%1"2;/"E($G<(1&A:='7>:==%5;4F(G/8E$/@#78".#,8CCH2AB4(95+FC:AB8#-5)?F,0;=>3E4/&H$%B%;3
@r5616
CCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGNATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGT
+
4#"<::A5B?@D!H1!,!D.&8;*@E!+'F00*!59538AE$,2A&@,06E1E'@65G>,=H6@!+1!/H0;@@!3A#1;+/"H;1&F49F#1>@7-C=)6$+1#F.E22*'(?GE)&15H7:D4.$2))H6AFEFA00"/;638+>*=E-?,'8)=-A3;1)4C*>48%:.'6DF#$4?A-2*)6(@9H5*
@r5617
AACTGCTGGATAAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACACCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGNATGCAGNTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTNTAGTGTCAGATGATGACCGTA
+
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
@r5618
NTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACNCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCNAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACANTGACGCCGGA
+
&A?(9?H8/,H/:*6)+2!9#B+CFB/7,>-:H#;E+8:9$5!!38D1H/0&+3A->)6'A3/",AFH2!DA=>5*B;&*5H37*27E4?H&B:)G4B<4?A?*"@-.B9";7>G4EE5H!$A$3&&<F$!>@32D73E@E6/E=A"(C2E)F77EE@>)-C+H$3A);.06)?(%!.+:$408:2?)+D:%05;/E3D.@>:(*5'";3GHG9@'A@"?C/.>?5;,217E-E31;,!'-#>7C.DG6)0-'#A!F/7DH0)6%2&C:/0$31/0H3&.@=&6(*,=&@!):17FH;E50$?$:3B6G&C>9,#-:
@r5619
CCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTATCAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGNGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCTTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATG
+
&0/=*H!046,),29G,6=6BD?!F$+/"*8C3)?<7;D5F7@*!0C<C-2B="E>"HE@=;"@?448'+?.*?((67F?42"7<H*?:/9:!(@DB(54?F>9*(%.>,7/&/*#$"A((3$B+76(76E91$BHDD72?##:4/$"81C/3#"40</?F'0H!E,-,3:EA:/>6F6%D)'6&F2&!?-;0B$A;/G$#,,)=H.G>
@r5620
TTGCATACATTCAATCANTTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAA
+
-662,)9+**5A"<%(:@;H'@,B+!=:&&*+:/0**!5<;=G"?7'@*EDE,@>.!;*#;E7F9H$,:A(17$24H*AE%*-(A::F7*-5:.9B,:)G;H62>709A8
@r5621
GAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGNAGAAACGTTGTATGAAATAACGTTNTGCGAGTA
+
;?<H4,@#3!0=4A47B:7<A.#03'A8/#01H1@/FE06"C=BH"4+<;825:F=0G*EGC&:/B'&%''/./D!&HC+7"F'4A:A<85C=0'54)C+8<GG-73(!-9D%2<E
@r5622
GGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGNGGATGGG
+
9;#C0E+E5FH2=6%9D0+:E@=53C0-$%="-,70>G#HF)%+.0?(*9.$+).E)<F?->?"#FAF<!>?H<4?/34$"!2@)*?5B#1596!E%2(1$,*A@@+%"B$*E;(2;+A1==*+E<#7+/F9@C3%6F7994(:CF$C3)7>0A-<+.#+F*?-$$(F2+?*;1@BB+2-+'H9:C>4&#>D-<)FC>05C*8<:)(F2-%/.DF,415H#)+/@!(>,8.59*8+;9AF'9$A#B30'
@r5623
ACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGNTGGATGAACGGGAAANAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCNTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACT
+
19%+)/'+F7!%&D@6,&D1>,34%%F8D/0%D,8)9!>4))9&-G6F6D0-@<DC5D%D'&$":H3;96?F$4H9(9=BA)=*2*,19+-D0/"0E7!3;@D$*:-@,.%1,@&C1.&DC$A8#4-.G8B6@$,<F,$;5.14?G5"88$E<GDB!A2B5A5#).+%.2.'8<<2E2&<1?'9.F5.-A<C<=>>C7H$9+5-.005(:3(-$&E1)93'3<H,&9=D=B+4<69.>C+3!E5@;!,,D%?1*#?8)5C+!H22:@(92+2-*HC,'>G2=@2,!?56$G*.?3:*!!)0#*/!(*&B1G/3;9-?<-D2$-)+4=:35)"%+E**C2D16)4D=#AF:4>!?.C@523)#9>6+<,2(C"!GA)H4"
@r5624
NTGGGAATAATAAAAAAGGAGCCTGTTGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAANANGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACNGTTTCGCGGTGCTTCTTCAGTACGCTACCGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTNGCCTGACGGGCAATGCTGCGAAGGGCGTTTTNCTGCTGAGGTGTCATTGAACAAGTCCCNTGTCGGCNAGCATAAGCACACNGNAT
+
&DG>A0>F/?@-D4.0;D+E5#)#%;@72#957:,'071E*AF&"6(4?"H830#G<"4B?;B3+(>&E$5DE084!6>D'EB"H-"5!<B4$8A*"";6<2@:;(-5A):2E7,?;.<$,E&G(;.F0#.EF&>2HF5""(<*2A6.AH;7('C+(=-H-5..D:3GEE2488;(D:0&C@*#&!0HC'&"!D>%#A)9<2&7*'@03C,D,.F4@2)@)H$G0597=9E0D#D1@C@BD8$BF>/69$>*@E+8+%400*>2F"//(G-+DG==:9(BCD*@.85.3@!6/3+>)*>%&3BE>>3+%A
@r5625
AGCCCACCGATTCCGGCGGGCNGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAGCGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGNTTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACG
+
+&#!"%'*$$(%!)%+(#+&)'%$*%'$$)(%%((%)"*'$&!)('')%*(&#&!*$!$%)*!"%%!(#!+#&#%*(!*#*%'+*'*&+#+)*&'(((()'"#"!!%*(")#&'%""!))(("$&!)**#%%!'!#$"$)&*#"&!($&$'")&"%(!#&"+()!*+'+)'$&)*+("'%+#"#"(++++!&*'+"+*%"(#&#'))*%"!(*&(&+(++#)#%$"(#"'#&($"&((#!!"$++'(+(!%!#%%++'(#''(&+$+"!"&(++$'+*#+#'&!%'')+%'(%&!*%$"+(%#%$%&&(&)!)%)+'#)(+'$%(+*%"(&&('+#*&*(%)&*+#$"%*&$))(''$)*#)()#%
@r5626
GGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGCAACAGTCCAGCGTGNAGGTGTNTGCGGGCGATCGTCAGGAAGACAGTGNTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGCCGNTGGAG
+
F<&3F.H%HDB966''EE'%-(>(86!9!3:?7%E>/1D*=(*'/A(#H9@H?-B98DC&04794A)A+;5-D9&C8584?9$A<CH,E;+C/2@,>-.7"3<<7$D2"3$014B1"C%;*(;B;8F),3C+D"@E%2*
@r5627
GGTCACTAATACCATCTAAGTAGTTGATTCGTAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCNCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAANTCGTGAAAGGTAGNCGGATCCCCTTNGAAGGAAAGNCCTGATGCTTTTCGTGCGCGCATAAAATACCTCTGTGCCGGATGAAAGCGGNTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTT
+
-##3&",<B8(E!+C384HF#A*B?)1"G-2E)"F'37A@C6$;,'@;-@#-.;4<:?31%7>"*-+80('8(=:A+12"9!7H+&+:F&6&!A45,*23D&-&>1H!*!3"=/)%-C-3<<3,B%'E6=:><4)3GA%(%=&E18:3*9$H8D'341,D5)-++<!>8)>;8=5BG<9@7!912A?7H+<91/E<(8H#,%-A='4H0=F0:0,>8GE#+6?;#%,H;#$31=))5)>!<"F=G#:5B752B?F$F,((--/?@/<-+$4,38>.,=,?-$8"@EHEF87>$0'34&)>B/%3+@#A@6;&%0;#79H&+2EH1@D4784G628$9(AH!#A-:C&!$@?=AB546(9&H=H?*+#+?A2+%H&9=2/)A=D,"$3)(E7<,?#D>'A0=59$8=-?57:@E4:""GB:*"D.9:27;D5%4?%828@!+=AD4)"C(+<C@GC=4D5,4F$-20A3E.B0:.C(!&$"#BA5)1"A=,"3#C;'
@r5628
ACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGAAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTG
+
6!#DE>".=54C#8)G-+88H>4+0'.8F2!5(,F"3"C=@6;>CC6C*+$GD1<7<&:;B:C>&D3G%2$7;>=?+?!>CG9@>1&H%9/DB$&0?4>+71=>8;A-G@G5'8#6F?&@2-6!&+422G<H#)=7+6=?#:;=4&>B1?F%;;!,/=78CA@9%+#,1805@,.0F5?;6E#?<*D9%496HAH4G';5&H+4.>*G+'"FAG4..(-7'(!?CC/D51<B.6G9!C)C3G%3:A?B4A93C>&@+";>)!G<G03D>D/A#A,.E6'34F//5BHH+?:B(?6-01B(:%/H6/7,2,6'9@$%>>!G5
@r5629
ACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCACTGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGC
+
/:70H*?#5D5-=<-//;#-<&/E>&0'?F<0B9A=0B'<#F25E*;!*9G+@5!!4$:CAC&GHF6CAG*?C4?H-CH?;)'HC$/G))&D5>)=2:;7!2G=(2>*18?"B6C!&@A"5?!HFH"&;B?@0=.C2*>(C(AA=729C"5E#@B:"9H&8':8?&&1F?+F;9./@6"3//7)$-'7>;,E?A):6=/%55:2!"(0?1&-=H%$G!64A%F"7E71+G7.&;>!7+8-4=GG$@=1&0#D/:81%9+3:3E!/42F*5/A@7!<=<6!)"<#1
@r5630
CATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCANTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGC
+
3DG,*B30)0=E-/">HA>9$#"=1>.??4;&6B7H&F:$A5(1":9.D#<%E#7@+34=-#8G;59/(.-+C(,+<&(E!((/E0$<'5D.'4<'2+*>0BGF@HE8A/=E2B7#---&B&#63*.6@>.04-B+9+!+3'?;0$&=>."#+5:H(C@%-)E&=':-2A8*C%G<:5AB48F2(?''H9==98E(":<?62?601009!>F1AG$;!0-<D-@.%.*4B.($3!*")D-(E=3+G%7*>A?:3(&<!&ADA;4/(6"+4.4##'@96E&'*9B--D(*#1:=239819%'1@8"FF+#1.8,0"6G2!H+:'83%<718*+#+6#EGFH2040C1":
@r5631
NGATATCCGGACGGATAANATTTATTGCTTCTCTTGACCGNAGGACTTTCCATATGCAGGATTTTGGCACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAANGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCANCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAGACAATTGCATNTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTNATTACGTCTTAACTCTTCATATTTANNAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAA
+
),E3..%C8@4+**42$F,.70%(!.-DG-8&68-5GA!00;1@C.?G$&E1.H%*G53.7:%'>B+?$,9(2$-8?8A:'D.'82H<F.'1%D!?1D/64#)89'<A!41,B)*:-2A$/G(*(FD,6?(>@5/$$!(!"<2.*A>1!?,17H5CE=-6**/#5$0C)(=-#*?,8FD3&.47>':+(A%@@)93%B'%F143)3D-(#(?/"$CF!/%E#.4A?!.?.H$483($051B6"@*-D=3=2+6?=>DB1E@0H"2'$16AFDA0!+92"F!=&+@BD'+9!++?+@)<0;'$.,*7"*/798.@%89!#<F:(<$DA#FA&8#+?9'<;+F6:.<:#=&:1>A3,8#:&@:565"'(%!)!=-2<)?'4G%8C,1&>A?H6FG:!"3>(+4D>87>B&*(=2+=A.4)-1'=-*!:4A'0<,#CD%"0)>'>3.
@r5632
TCATCGCCAANAAAAGTGGCGATAGTGAATTTAGTCTGGAT
+
F)G9*;G5"=;H4&3$=98.7A,53D0"#,#E2:G/4H=E"
@r5633
NTGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAA
+
$(.6*8#H&H+(E,!,G$$D7*B1$'3/)<);?=(0<G,!AA+!@&">ECE!;3"2F"62<6%<1A6A4&=<;0F/&<A9D!?B48=2HE@:0#@0''#!#)2"F-/3@H'/29F-3'=-@#:/*%1!2,8DF
@r5634
GCAGGAGGAGTCCGGTATGGCTGAANCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTGCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCTACAGGNGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCNGTGCGATCACCCTGCCGATGGTGGGGGCCACC
+
619.$4&)**.:8>F:47FG+D=&86$'0-04?%9+71C+#(6=:7#1$,2BC@GD+A27<'</50,-$1*5BAF<?$>:68#'&4)!"C>-77D=*B)6+)00.*1/;@E07E9(0!6%:1%$<2B!<'7(,'=<(C6HB6->:(6-=>*!#E2968<F'".(A+(5E<8=%?1G<426'B#%5G5*79<+E"(.$9@?H(1=3=14.0/+"3"6H'9+B$?6521)EE@,$G:,G-,,,%><4%*D&%33,>HC&B>DE6".642;"&"&#(E3;EFG4?+?*CB*"G&H:/.?<FE@@$D+BF0&CAD($$%?1A2'B!+"C*74=($?4HCE?4C9-EG<6$?:553AD0+GG4G?'5"+2"H/&763E>A/.H:FE'!1=CE:/A/;$B
@r5635
CGACNNTCGNGTGAAAANGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCNGGCGTTTCGTCAGAAACTGANCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACAGGAGNCTCTGCCTGATGGCGCTGTAATTTATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGAGGCTGCCGCCATTGCCNGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAA
+
$&*%$!'**"&#%++#&%#+$)!)###))")#+$&*")&&*+(%%*'&")"$+")!+("*)%()*+&('#"&("$')"%'%&!++'$(('"'*&"#*!))$%)+!+(!%!(%#+&%!&+&')'(!$'%!")+$(*%%!(#)!*%%+("&!&+$($'""*''%)$'!'"#'"&+"!!+"&!)$)&"+)!&&*''"*(&))$)&')''&!(%(("#%&(*+#&%$(#*#%)%(*%)$&'&&*!**%)$)*()"(*(#)(++)($*!)'"++"!%&'!(*'"'$*('')(%&%$!+)!"+%!'$&$+##+(&*&*&%&+(&(+)("(%)&)!%'(##&'*""'#!(+%*""$)('!($!(+&+'+*(#*#&%&'!$##&("+#*'#&#!)&+*#+'"#!+&!(&#!%$($$#&("*!&!%(&#"+&"%'))+
@r5636
CTGCCGNGCTTAAGGGCAAATANACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGAGGATATNGAAGCCTACGCNCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTNGGCGCTGTGTCGAGTGCCTCATTGCGTCG
+
F$!DB=B+B-!$&,;)9-A1%E='*4"=$@+#C;FF32G.>"?B74#$(.$<=0+$E6"+F'/6@5>'?$9#9B10(',.A>8*2(G')!424@<C8<D)3+H!$C<0=AG)C$+?H."1;!"A)1,44F6>)B*;1E3?.*A806-"9>-$?+:6=>+52#2(HG0G;$:#+,73><7@,$*48A=)-/?H)*9$!+2=H4CH64*GD&8"3B1D-&2;/:A(#(+7494</.55$>7*G#7("1
@r5637
CCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCNAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGNACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGA
+
*+"((+&$'#+'"*%(!&"&#%&"(%!)%%*!**#$!&+#!$*)#%+(#('(&%$"*+&*)))"#)#+()+(!*"+%#%&%&&&#$%*)++((%&!##&"+#"&('*#!(+**%+*$&*"*#$%'&%)!++#+*%+##'$("%!$!))*&#'()'#%!%'*!!!##*$+%&&***)!&!#&!"!!$+%)))#+#!**!!"$'!!"$')+(%&+'(#%('%'
@r5638
CGAAAAAANATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGAATAATGTGCAATAGGAAGAAAATGATCTATCTTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTNAACCTGTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTNCTAACANTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTATCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGAACTTCTAATCCTATCTGACCATTATANTTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGG
+
(*+)++(&*"*+&%&+$("($+!($$#+%('&!#*$#$*''#&"!')%&$*$!'&+)%*"$!&#"(!+%%)'%('&*&("#&&#%"$&''+"%%*!!!("+&#*!#"()&*($(*()(&)&#"&($$$+(*'+"*'(!)!)))!#!"")%$*#"#)'('*#$*&("!))+#%$#!*+!*#*!&'*&+!+()*$%(!$$(*"&'!)!*(*)*'+*&'!*+"+##!&%%!$)&)+"!#(+%!#'%$+$"#(!%'!+!#(&!*""*(%'*'$)"*+"'%++%("#$$!&'+''*("+#%*$!(+")$!(&!&$"*()'#%#!%##(!'+""'""%'("(!()&%(+%$$')%%'*$))$+$&)$"$*&+#%''+#*&'%!#"(*)#%**%"'&#$'$)&('$"(%$*#$**+(*($'&!!*)%'+##+&#%$*"*)"##')'"&"*$%(#*'*%'(&#$*&*'"$)&$$"$!!()())')"$)%)+!*$$))%!++"(*((%'$(##%&%#'#"%(%"&'&"(#+'"')%"#&$(&%!(#"&!)"%()("()*$#)&"&($"+!!((+$$&!(((&*#"&%')+)&((%$)!$#$)")"%!(%$!*'!+#**+!$$%'%'($%$%&#"'%%!**'%!!(!%!*$%++$(&+%(+$'""+)$%$"##++&!#(#("**!#)$#(++!$*$")(!#%$%*!+!+)!%)%(!&*##''(%++$*!('(&%&)+)!'#%"$')!'%'('&)#&
@r5639
NTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACACAGCGCCCAGC
+
&))+(&$(('*+'&#($+$&!+!'*!&$%('&')*%+("&+*!%!#!%+!)&%'*%+*#!*""$(&#+'%&!+)&'&%)$)%(&)!&'&%(+&*%')!(&'+++#$#"#)+"*"+%&##&)"''$)"(#'('&**!!'))"$&$'((*&##$#))"(%
@r5640
NANNCAAATCGTNATNCAAATTNNNNAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTNTTTGATGAGCATGGTGAAAAATGCGATGTCGGAAATGTTAAAANTGGCTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCANTCAAGTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCNAATTAAGCGATGATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATG
+
!*""&)$"%"$%&*'%#&*$!')!"!&*++(&&(**(%&$")(''%%%%+))!&$)**+*"$$(&)+"&*'"#*"$!%!(()$#&%%*))!%+(*+#+"'+##&#%%$+%)'!)(')++*%#*(%)+!#'!')('$%''"$%*%%#+'(&+$!*'#)&)$!%##!%$#!("&%)&!"&&)$*('&!'"&!%"("#)*'&$"""%)%!!)%!*"(%##!&(%!&'+'&+''!'!)"$&"%)$$&''##((&!#"&+(!'!"*'&(*++&#"'!'+)&$!')'++%#&")$%$$&""$!%%%+'#(%*#!#"%+%$$%"&((!$'!&(*+)*'*)&)!"!"+"$(""'%"(#&#*%%"*$$#%'$%$'($+!*"&!&((("*&!$("%&!("&*%'("'&'&+''*#+)!)"#)((#%)#%$)+*&)!&$&&)%)*'+*(&!#!##(!!&)'!('!!"$#('*(!)))#($&("'#+"%#&+#(($$*('##+"+'"$#"!"*!")(+)&")"+*)+("%)&*)%+&&$!($''&$#'(%+%*(""$%')&"$#")+"')**&'%(**%&%('%$$')
@r5641
CATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATGCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGACTTTTGAGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTGATCCC
+
)@?.0"4422-1H"<%>,BF9&=:BH..65)&9&?"#7/C/9?!9F(0B=B/F3A1"'41($:%)8B8H53>H&1<F+?,41+57>;,A70F1<?("3%:0(?-A3B3<D)7B$C-81@;C*=$56>,3:!,.0).'.<,'#43FH!DG5B:/#B:3+>2%1"EB;=:%/(:;45;;@GF!.:4-*>>&.D?=:5546>FG8#5'6?%$C4ACG'!B*1#%EGE,043.7
@r5642
CNCANNGAAAACNTGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGANTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCNAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCGATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACANGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTGCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGGGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCNTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACNNAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCACGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCAGAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGNGTGCAATATCGGTACTGTTTGCAGGCAGAGCGGGATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGNTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGANAACAACCGGATGCNGGTGCGCACCAATACCAACTGTATGCGCATGTGCNCCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGAGAAATAANCAATACCCTNTNTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCNCAGACTGTGAGCATGAGCCCC
+
(#%%!(!+&%'!&&!!!'*&''%***!")&+*(*&$!(&%+%'!$*()"))%''*%*&((*&&)**(++%*$*"%&&#"("()!*++$()*#)*+"(###$"($$'(('&&'"+'(&(&!&#&&*)+$#((&*)$'!"!+!)*!()$(+*"$()&!'#&)!&%)'!&*)#*+'"*$+&!'#"+!$)%%+#%$"#*%*(!&%&'&'*+!'!'(#$'$'&''#*#!'!"&)("$'"+&+%&)!+!*!$+*%))'("!*""%)))"#!&%$$!)$*%'#!*+)+&$($'%$("%%')"*&$+%(($*)%&*&'+*"&!((%**!$#$+#"%)"!$!#+!"+"!*&'$$()"+"$#%)+)'%!'%#%&(!!*+*'(#(+$+%%"($&%'&$*%!*!")'!)))%"%%++('$+%&"(+$"*($+)&%!)+)$*'))++'))&(%&*$+)"%)'+#$%$&))!$#)"")+"(())!!+''(**(%+#)"(*('")"#+(!+%%*$"#)#*)+*&#)%$%#&&)'&)'"*+$&%")()!!$*%*"%$(("++#)%#%*#+'!$""(++#"#*+#("%)"&$((!!%#)$(+'()+'$*#((#"+$#'&#+##"'+%(%#"!+*+$"++$+#+$'*"*%'$$(")++!$&+"$*%$++%'"''"()(*+*)#%++)&&#"'!!$$%!"#)%"()'&')'#)&%&'+&&++#&&)!#$#!*%#*$(')*'+%*%##!&(*"*!(*+*#))$((#%!*'$""&)$+(#($$(#&&)'())'+$&!+!#")+$")"#$+()"'#()%%++%+%*'*!!("*"*")+""))!(&+$!+%*&$"%!')!%'&*!****"&)&!'))$)(#*'!"%*)+""'#(+$)&'("''*)&'+%++)(!"!'!"*+&%*##"%**&$##$'+)((&&'%*!*#'+!%((%'+&*&&"'+)*&((%$'##&#)!(%"#(&"**)"'#(+(%+()#$+!'"+(+")!$+"$+(+(("*+$!*+!&'%+"(!"'+$"$')*)"$+&'()&$!*""+*$&"$'!$'($('+#%(!!+(''&%*)$""!')%')&%"++)#%&'$!&(*$!($#)"!*$*#)**&&%%'!+!&%"!%*'"''&!$"#(*!*)*#%*))(%+)""#*#%&)"+*(!*''%"#%"!"*'%$#(&#$!*&+""'"%)#%%&((+!$$!%)
@r5643
ATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCANGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGANGAAAAAAAACCGACTTTAGAAATATCAACAGCANACTCAAANCATGACGAAAAACCATATTTC
+
AD?&=@E@23%$H54%:/&,=@($,F=BAF$%>6C.%.GBDD10=&FH@#?>8A'G>(!0#H>D=(1@;9&G*58C,,*=GB#B3-C)(;%G30><D:%;?&4#08/D:&)F((=E/=D?,2AD#/)5&=B;#4))>+,-/*&F$!0=?A<G(!7?>"-B,3>/(71,:F#-=7H+"/#?@*4A<?2-5+"H@=02'7H(C!@7E*5;?@C<4><"9-072&(DH/"*C<)>1A>4-%5&$G$G(5*$?FH9.G91D.!F'.(D+DG<1*G,%C:A@6#@EG76(%;%1$@,H--H1/*7F#*E3F:82;;#>(?&,DD/'@:>"02*G>)"E/$<H(0)H?H16)65D9")D&E->CCF4?936+E+9$<);BH(B!:<E;)2%@6B254*.B><*?C35-28D"B>%'2"G7++;/:?!81=-.$//-D;4:/1"6>4"0%;404/3)!:D#A&+1&)+$B6A)05.5/>"H3<%=6:E=AA%#*+!F0=C%8E!*E/G!B4,(!2-*5$E%-&(3-D/A/;8&$D+(@2F71B#879'$/4(,3<A?<@*1&+G41&>")=2$>4;
@r5644
TGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCNAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGNTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGANTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCC
+
-+%,/.+2/'BF)#?5+7,"=@420;FH,&#A&AE#)$:,D#>*7*#=++?!2##')1C@3F9D@C8)%E6:16)3G782H+*'%:(?<#57$:,E@"!%*:/$@6$"$-053D8F>;H?403FD&E"'@%0*3@3?926)=<?+F3@4'A*3%5,%&!/+7;7H#<=?1.H"0@8%7@@64"/F/F"9"&3F5'2'?3D!+,9;D4C3G54D2600*7E/1-G#/(!;4&/5G:1*&+G7:%(#%G@)G*$?4-!@H8A6G<))+606-&&.1-6@6?)!E!1-4DAA&*$E9&4$>$600H'CD-*D"H*#/=3(<?-4?=&08CD3/H-")?':D80B%C#%$04)3:5F80?3>E3
@r5645
CNNCACNGANNAANCCTAACACNCNNNAGNTNNTNGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTA
+
"!"&'&&&)&(($!!%"'')"(%$#"#"'!)#"!%+"%(+%'$++)(*&!&$+$()'(#%!#(+#(!$(#+**""*)*"'**"""$
@r5646
TTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATCAACGAAGACGCCTGGTCNTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCAC
+
-0%-B>;#H'%AG-8BFC<>C#'%"B0D!$;=@HH7>GF3=4FF=<C'<G;4?A1:H<H?8G89H?0<+H4FF3@!!6!59=,E&4>F94H52,0$F2D)0C6*@CB>4AH+B4+(.7DD19-&$+#'G5',)4/.2-'(A4&>E%)-F1"'27;4+FG#71@,C:2.G(.D5+8>&"E=9=$G1&=(2,/;@(-'E5!00C4);A#//!6/37')4'07<30(!#;A*BH@@-A1D4-/9$(>3)."F::#"3,=-)G,3%&8,<8()@$02H++!14G9,FA%!H#F47G@3#
@r5647
CTAACCAATTCATAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAAC
+
A>'(.7@:'7(**(=E:<2B5+HD;*E:).(2:G"+7+:1<17/1&$7"''/<1.*';*%"=075'(0H;;(3/##+$>E(-*0H;<!DH%5,')"E&,2:*:"#75362>(#<>1C&)C?&-<)('-;AB3>D%&GEH*3/.:@%;?=7B5%?("DH6F*&GA$9@0+",,
@r5648
ANCAATTTTTTNGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACNGCGACTACATTTCAGTCTGCGTGCTACTTCTGTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTT
+
966(E8GF>3<?'3,?H=":/-*C&;4HE+BH!6?)C"H"0+H9)+F#;A30C0,*F/+ACDG@A'(%0!70(+*'H+5(4:+)6+@602?H'$6@47.2!HAD+%H55'<G4$3E&(B8D@:<<=@28?7D@+HC+#"<E:8,<81=$H==:3A%A'GBC3(4*)G6?3;>0H@3%%))2/4/-8F&./1HFA2?>,.H.%67H'"8136:<"/'80,!%5EH$?#@A'%'=-3$5=F6<!C)$8.4".,6->G31#8,1>,42<#(&!+,*D"=5(18H"/9::+,HD":>+#0!!D&)028.62/@C*)699EA:*":.@C%*?1';>=A77"H@)>C9+B>>B('%9%</445:9)?A/</'4=>-0%*++(G$$98<,8$;(8"<!.E;-'G)6C20H@("69(0D;3!!1;A93%&>>8+.+'E1/#.=?.@/;<#B
@r5649
ATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCG
+
<"-1/-FE$(1$9/>3HC!,2A"5B5@+.3-1)>BE<0()"5-6E.H<2&&/0#3+C1@:-<"4,"7"<,;!9,5&E50)()$)-3;)/$?794+,)*8=.&-*%C'AH-D1<AA;70'/$9#AF&CF>?CH$+>D<H>5EFFBD6#HH0F>%<*$3"$!
@r5650
AAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACANCTAATAATC
+
;?=/B'B*G93,#AB'@;;%,#1B7943*GFGF>.+@&=9+EB")2?,+A2D-*'-8@GF>2F-79C,"$;%H98@BC%2E2-<9
@r5651
CTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGAGGACGCAGCACNTCCGGCCGGGCATGATCCTCCGTCATGGCACAGAGAAAATCATTCNGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGNACTCCACATCCATGCTGTAACGCCCGGCTTCATCAGGATTCTNTGAGCCCACTGTGTTNACCACCACCNTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTG
+
%&+)%&(('+!($$#)%+(+&'*+##())"%*'!%"!&)&#"#)!$!))($"*!&*(*#'#)"*%)")'&+!+$&%"$+&*(*!*(+*'$!'""")()"("&#+*)+%!*(%'$'+!+")*"#('%%*$'$"&)!+'&""!))!#)+$&&++(%""$)$%*#'$)'"*%!)'%#&#(#"!'###!!%+)$**'*&)!)!*%)'&')')!&('''(%(%$!$#&#'+#&%#)'+)*$$&+$&'#!&$$)*"+!#*#"'*%)'+!(%$%!(*#%"&%!+)$+*'&)!)"$'!#'($!*##+%$"+(%!)+&%#)&!#"("!&'*)'"'#$&+$$*((!#+#(%)''$"&%'"'$%)*$)')&
@r5652
CGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGTGNTACTGGGATGATCNTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGNGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGANACCGAAGCGT
+
)E"7#C9&A+7F9-)&,2#?A3EGC#:1+,CE=<?!HA'&;0%/H&/</BB8F7$G+"6;4@&%.8:%7D:3@%?'.-B&B,"%2.5A,3!4@A/C/?*5#5:)+:8-=(?"A*E+@%$1)4G'&<&(E=416=81*%E#G/05@601%+>B/E?"*=-8HG""FE+$#9A.<21:
@r5653
GCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTNCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTNAGAGGCACCTGTCAGATTGAGCGTG
+
GA>.-0A'G&C=,&<('2?FH,.C>'F4*A=4@8A%"7,)$.B=AA-E>#2.@EC1A7G$#)>HBB/?<1*-+D8DBA"8'#3!'B4;+"-5B"A(+D#0GH+"-@C80/+6D(4H!!8*G./>,F)B*:D1E79&G7>)<BG</B55*,5A2=8"+-)6GA('+>A*5CA#B7>#721)B2<<B,2
@r5654
AATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTNTATAAAGGTTAGGGGGTTAATCCCGGCGCTCATGACTGCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGNGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCA
+
4?!")1*>7H"=D5C4@48"@!CA6;<D+H#E8H1+A,8A==?18H'.A51&".?4B:>&=FG.=C.1(*94$60DA71?5D9;>.6E$AB'%C5@AE=&3:-F&6!+,9C)D*"6/0!#=?0*+G0F.G.H//7&0-6-A33*>*.-->27"GG5@:"5($).!,<76F((4A!,("=E'+/B"H?/:--6@=/H72(/48+A%2%2'/$3HFB',.""#2+((E"*9F('@H(=0*(55C13A2884F0E47*H'>;863A0C6.C"?70CD6)#70:&EHGB/(8.?/=78,,@/8A#8
@r5655
GACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGNTACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCNGNTGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAAC
+
F@%4%-+6;8?%/F(G3;5-$7%&92->.:DFFC6GCHDD#45,@,)-3,1&5H-$&;$AFC'=':-/2:,1-.9.?)1-9GH5(/2756E21D/'F&"CHE,D6+5FE<,7+<:H*1<;><9)#2$=3-A#33/153-GG%G7;;,81:78;-F,,!DB-=:;6H/82<43G.;=A:9G#)G52(=AB,>7FA)..2A2+E<9,=6<38,=A."*0#&:7D:EBEG875CF'35)/BECEE2+11+%E?076*#7?G==<3"'B12G,-41.GF@"'&,;?7FD4A,5B-F*":*F(03%,.+:*(C!C"7D08#H65:@4%8-?8>,=:"HG=;H<=$!;@3#2>6-339<=+.$6/F*;3GDF6DBA&/050B<=H==81/*8F:@+*8;%"E/2B)7CD**=4C'9"H
@r5656
CACGCAGATTNAAATGTAGTNGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCANCGACGTTCTCATGGTTCATCGCGGATGGCGTGAAAGA
+
0$@:G*!G<5*4,/8=0=(&G6'+E(6?<$.CFH,-E<),3-:G@'-)5!"F,5A/,!=#44>'DH8/!15/?E5;615=2"D0!37<'.G$@>76H#%0.7"+.!(>@A>+2/7(
@r5657
GACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAAGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTANCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATA
+
;B$.=31$D)0E'!"E"=&!!37&&5D8!0F?CF8.>E4&0A#,DA%-H@6<*)#"H7!9=,7<,A5H-#(!'&%.<*3'F'0>#,$%8'=HFB$>6/=BE;'2+&0!7.$8)*.A78.EH93F.(,?4!,6,"#%#-8C'AC#!4#.,(.C'2;$43G'#6/&9:G4/0/F!F<E$0DBB$2HG@H"*<"1;2',!%!8(02-1/=!=2H>@G@')E@EE:./H6&%7CA?.2(8
@r5658
CGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTNAATGAACGCAATATTCACAAGCAATGCNTGGTGTGCAACCAGCACNAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTACCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATGACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGANGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGAT
+
EF$)'+E>D/C/?15.@E119'B303D>+??9F223+F*6.4/=5,A8=.B/3*(,$44+-?"F-@G":-*1:(E83=H%2<!!9/3>.=3G2CB795*38%#F9-#$.(#64512+)8,:?,=%G3G2>C@:3F5)/B(:9!)(;G%EBF=E33"?.C&6:%)-@#7'01$&5%=-@-9>+13+&H<G+<@F7D==?-)&#::B,3"0'#9FH$42'9,@*D,:*5>2D@-./#@C**01*CFF9<FG5(6HH1;-2E:0'0%8;F&AC)2';%H0B69C8"1#!&*9>4+E+)2:!;6*D'8&@C&!!((()G%?**4::4-C$@+($%A2/2.F@%781B&):;AGE>-7!$;F4/E#3711>+B--/#-#&4$F>,!:'<CEEAG5@9"'4-'C3:78;&3%G(6.B)CACA9,+!4DAADB?B""B+?#>.=E2
@r5659
NTCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTGCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCGAGTTTTCGCANTAGATGAGGTACACCAAGCGATTCATCCCTATATNGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCGGGAACTCCGGGTGCTATCAGATTNTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAANCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACT
+
!?B>H22*>@D(?!-;)?./A)/F0):AC-'8F8%%66<B+E8%)559$$F,2FA%8*9$1G:/:-<.0=)2G/!49E3")4F,-=FH/-7!AH15D!E1B$'<C'D./%>A>5$-3#@=872@'+,%?;<'>H%#<5-(+;H4=@3H=E+("1'*F55?=8%C.E;:1%8D36&;5!C;;AE-8:7%-3=C&3,A(3FF>55C&:E6"D'B-;H7<95*F/>=E&B?#:F3,#8C9)8/(!%+:D-7>4;%"#%--?="G%4->;,#,+4GB9*:?E.C=3)8AC#A>&25@&#3540<%19&()CAC5#B5#(70A'"(#$5/-.#9&9":(:-7)46B$&<
@r5660
GGNNNTNTTCNACCTGNCNCCNTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCANCCTGTNACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCNGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTNTCAGCGGNGACGGTTAACGGCAGGCGGAACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCNGGCGAAACCCGATCTACCCAGAAATNTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCNGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGNCGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTT
+
&*)#')'*"&!&)&*("")&*")&"*+**'**#$&*(#*!+((+(+)!+*'%+$!$)*%*)&"+)'"!(+)&!)"*#+%(%()!'"%'&!+!)*!*)%%&)"+%++("#+(()))$)%&'"&(!*#$#&&&&+##)&$+'$$'(!"!+$&)#&+*(&"*"*)%#+!#(!+&##')%)'&()+!("+$&"*&!%!#"))$$*%*"+$&%(!%!')"((#$$)!*$*+%('(*!(""$*(''&!!&+**(("&('"++(+'$$%!*&*+&(%(+*)!**$%#'"!#&$""(!%*$$)*!*)***!$)""&!'&"$("%%''"'!($*)*")*$!%*%"!'%&&)"!*")!#%()&&"*)&(%'###+!)(!((##!()%%#++%&+&#$#+$"$%*$&%$)&(')!(%''$%$(%*'"+$("&*(#%("+")#***&%+$%%!!*+*!%)&!'*'+%(%%$!"("!#+$**&*(!*!*'%!('&+"(%#*""+**)%*()'+&**($#++!)*!(#&('())%%&(+&*$'#$$)!*"+$)+**#"%+")!$%)%+))$*&%$+&($+*"
@r5661
GCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCC
+
<:6-G4"HD+E-1%@4?4)::1#<29)!)5':2=$->'>3/;18&+8A=6*@A$9(;"0'+;C)A!C5?=6"..#';@A3##$;45CC#4(-$8GF(>G&0@36B(820E$9E-6>,'"9"D'4*92F111A%(2E!DD(3,0/!)EE:?%A,78BC
@r5662
ATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAAT
+
-%,FF&*A4.75/G=0?70,G8?=@B<E;:AB7>?%/'5$H;B4<C7$GF4D=D$1=@G!<G*"3=D?=4+=1?FF>@A(F/D<9-G6+'=H%9*76*;+"60!=#*19/0F70)6>'31C(4H"4?$37@%77$,DA*1'=/1.@*;2E><AAGAF5;A4H
@r5663
NGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCATANCAGTANCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGACATTTAGCTACGCTTTCGAGTCTCATGCACCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGTCCGCCCCTTTGATTTCTTTCACNATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCANATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATAAACGGAAGTTCATCTGCTTTA
+
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
@r5664
AAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTNATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCC
+
<9B*$"6,4(574+'>'F"2CH%?*G(DD63$*''%-)0:)=@@<.#5G*,(;4"0'-:602>#=>%-5?B8#A<D6H;C'#?.%"9.019AA5F1??*1B756;7@2H'::9;
@r5665
CAACTTAGTATAAAAAAGCTGNACCAGAAACATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACGATGAATCAACTNCTTAGATGGTATTATTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTNCTTGCGCTANTTTTTNGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATCACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACANTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTAT
+
'&('++#+'*!#)*'"$+(#$%)!!+%*)+!)##+#**%$""('+)"((*)#!&(#"'&"&!'(('%"&!")"*&&&!%#+&!*''('(++!+*"**'!""!*+#%+#$&++#!'&%++!(&*($)'$)($"((+)*$%&)%""%!$%"$&$*!()(+**(%)*$%*)"()&)$($%$$++'&)(&$)**("$&'*'*+("&%$*+$+!(&&+$'&++'!$$#++%"((#%*&%&'%#+%&&!#"(**#*%+*&+"(%#"&+%+)*+&"!)'*)%)$*(!#)%"+#+&!)!'&+&'!(#!"!*+""!$$$*&!++'&$#$*&&!'+"!&"*(%&*#"#$*%###!*"+#+$))+'%%&**(*%)!*)$))*'++$+#'!!'%'+%$$&&&!+'*$$)$%$''+(+'#('"&&)#")$#+')#)"%'")&&)$'*&'&&'!'$&!*))'#)*!"('$'!)"!!)+*'!(
@r5666
CATCAGTATTTCCCGCTGGCAGNTGGATCTCGGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGGGAGGATGAATGACGCGACAGGGAGAACTTGCCGCTGCCCNTGCGGCACTGC
+
+*!&''!'+%"&("'(+%''+''!%"#**$*!$"*!!!''+'*"#%%$&%'*+*$))$*""+'"+#)*###')$**%"#*!&!("#*"+#)+(+'$#'$(!$%)%+#!)*"("'$"$$%!"*&!%#(*'((!!&&&)('+"$*(+#!&$%+$!)+*#)#*!+$&*$"!%
@r5667
CCNACTGCCCTCCAAATCNGCNGCCAACGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCNCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTNTTTCAGNTCAGACACGGAAGTGGCCGTAAACTCNACCCTTCGTCCGT
+
"$)*&++*%%+)'$)')'*!+!%&(&("%(!"+)+!'*&$)&*&####+'"(&!"!"*(%%)'+'*&)&*%$"&$'+))*)!(%)$)%%!(!$'()"("')!'"*!$(+(#&'%"!"("#(!"*((*&(*!%(*)+%#&!)"($&(*$'+&&(!$$$'$%)'%)##!*$''*+'%#"$%$('$"!#(%!*)%!*""'#'&%$!$&&#$)()%!(+&!"$)#$*#
@r5668
ATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTNAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAAT
+
75;?G;?:87$**,(!D9<8:G5$EH.*=:E$(##03A4!>/1+4C=*%H41805DG>A87)&":)0$!<B8-61C<&,5A"("7!*&13CC@.&0@,:,@7*4?'D@A?@,;EGC#7-=HG!+A""A7@9((+/(,8/''1D>@@0-*,+4.<+8"=09AEFCHG1+?5+:D1%(E'HHA8G53.4%-411*:DE4D=21*3G0H=8C=$B(D?.
@r5669
CAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGNTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGTCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCNATCAGGCGGGAC
+
&<-,;>@07B".!6E!.?>$**=DH5CDA94B$12:(2AH;C/&"+-5591A6EB<B/C>%#8:<>%5%9.'H4../'C3129:-:=$08<E$'BC!9H8CF#646<5E251-9+@+B/7G)5=07D7>&$B=";*@+D.H?4C())0D8"B?(D<,F#!=1#18?G'+.)95=F';"&,5"!4&(3FB$'@5F%#;='<H6
@r5670
NGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGAAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGNCAGCTTCAGTTCTCTGGCATTTTAGTCGCGCTGGNCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCNCATGACANGTAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTNCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTNTGCT
+
(+*+"A?>-=&9B'HD'93&*19):'97@.$=-8A)=C6-,B":)6#!F29.GCC9,+5#9=CG/"(?%"1G%25F(:#99DF;4(5/.E1*.(A#8E+7'D<+G1$<!):.B04"'#"?7@65A:9@>C#.!8F;F$$4!6D&D%=8&;2=2=?,5#F&6<!C.G%##7A0A0G@.?>+%%A"*-+!*:#645'DA!/8F.7;D=&=/29!::@&)="/8H!+F19&)),<39&C!&C19@H@(B5+0@1C52"%:-=#@8H+:%%<C5H$;*D%@?D%',.8%.7F5018#///)*5-0D0:%-E.3)&),;54B8:3G@5D$/)B,!3'>C7$)*9:#:91%>7=F%=(*C$B%,B.$."/5&8+'5#;#/((%#G4!4$-2:9?6,+51D
@r5671
CGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATNGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCNTATAATNTTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATNGAGCCTGTTTGTCTGCGCGACGTTCGCGGCGCCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATT
+
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
@r5672
CGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTNTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTGCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTTCTGCACCATCCTCTTCCTGAAGGCTCGCCAGCNGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAANCAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTNACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAAACAGTTTCTTGTTCTTCGCCATCCTGGGAAGACTCCTGTTATCAANCACTGCACTGGNGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTANCTATCGACATCNTTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATACCAGAGTCTGTAGTGTCAGAT
+
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
@r5673
NGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAANATGGNAAATATGTCGATAAATGGGCAATNCGAACGACGGCAATGATTGCCAGAGAACTTGGTAAATAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTANCTAAACAGGAGCCGACTTGTTNTGATTA
+
!?+D($3$;9:#A.E=EA&465)F3;").(9'!89=C'B,58+F,,@4..073<>47<.1=7H"'=2E<%,*A?B%79!'!>::A5-D<@;FB#4!4:CA<-=!'2'<'B8/%%3!AA;+?+=((2!>56'H.#+$!,B:D-/=#0E?5+&0+F=!%099,9/A5'%/"?1:.B?-8?5:.0)$D13-E3/G=-40;,G6-;.)1/468%B@>HG)%6'')7@8F0H?/@:/5#C/DH-!'
@r5674
TCCACCGTACTCGTGATAATAATTTTNCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGNATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATNTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATNTGACACTACAGACTCTGGCATCGCTCTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACNTCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTANCGGGTCTTGTTCGATTAACGGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAACCTGGNTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGA
+
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
@r5675
AGCAATCCCCCAATTTGAGGGATGTTTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGA
+
53160(H=H6B$+;9:'0:7.D(AA89A(=508$6,:5'')8:-.,A4)5)C<G.B2<B9)E/H/8($")G.&:<3:FG*'
@r5676
AGAGGNCTAAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAG
+
$'%!)*&%+*%%$'(+#)!!+#)%$'*!'*("+'*#&%*#$*'+*!&
@r5677
GGCTGGATTNGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGCAGGCGCAAAAGTAGCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTACATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTNCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGT
+
03<9?$3=4B;,>$9+(54@:$@H@G!F(+H"D'*(*)B3)9+&=?@2$=3@$).:<".$%C>7E/9#1#AA7H).#-%-7/>3G5$5';$H#8+C(>6!#1A#"+*661F(BFD.C/!+6'EC@+73/$28?G9&)9,-H@B'E@$0+$(*9HC(H!@3$42)0'-$1@"/D:85>C/(-6?4/?G(70("<=9.'8"E04+1?664!99+;*>,-0$B#186#@-*:);?=6A(.7A3
@r5678
GGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGA
+
.)$$))+??;3<)8*@:-8F,H6H$2)%&?F'?;'G8D=E%1;;':>6>5;:>?;,#=#9B!0F!!;8'*F"?=C#D618+%+3*,,=G;034#F69A0<17,"9CH*!.'>@=*GB@)97D&A!5&1B<*!-C5$4@19"?>)54;3.)'+6$0$D+!D5=A@.08H:.00/)H*%
@r5679
GAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGC
+
.2,(C=A-'EF)<%+DH4,&44$F6#3</55(6:&B9)3:%G(G'B!(6)=%&@+-G<.*?#,3,(1F%%?4,A/1>G?&&0-4H?+<4F7B-"!''"?5B/?$:AEBH4%,@(6*?-D?EC.1!57/D=E!/((/!=#=*<+G;E,-8H=A*56DC22:((-A7H:,$3'B-<+C3H8=B90#
@r5680
CNGATAGATAGCCACGGACGTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTNTGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGA
+
-74&!(+1.&4"8%$>!HHE$'@?&).F1;<1/?H,:7A=,9;3@C>#4,61(7A(F7*>429D%#53F>9*4'*-1(62@C48BDB71B:?<28=89:0;C;7(4)H-/%E0&AB)3C6610B*
@r5681
ATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTNTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATCGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTT
+
8(681->4F<98;+8</<#+>&%<"FC@8.*BA9'*45&2E3A"=04DD1A3*=&+?;H2-(*6//<'@E-#G>21#!2'-H;6/EAE#7*D2457!-'.-*C'H"+7;E)B?1*A"9'E)8&,H1GG,"%6&$0/B:-;5%"H,E#!2&+4BG4/2"&:F.9A1C.7=.A#G;G@+,F3@
@r5682
AAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGNCTACATAATACTGTAAANCACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTGTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGNGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGA
+
101F8F>#&#='9#+:<G<89-8&26!;15>-,?5"?7-H6*'?))>F=6>E69>DC<'+<2;CE1!E);$$(="8;*/<="59@F+488:>8D:,;H4G=,#!6>(E&017B9'<>!2A<H7>>3>)?;$7(2,;&#E::1/F!8<;*#<0%A:%3*6-<,!$-AC%G!BE$3';C7,115B0:GH$*@4B!>7"(%9@2:(C',#$@#8-A,G;CG.1.'9H<D!%1<*<H:/1&'#/+GGB&=&9:2A0;6:27A$3+BH;'?A71($H)78'+4!F=-+G2?4D;5.H)2A$*>/5$<?9;*?2'FE(?C/81D)16HB47%&-3;;,*1>%5BF'=1$291!,A.,$
@r5683
AAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTAATGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTNAAGAATGCCAGAGACTCCCCTGAAGTGGTGGAAACCGCATTCTG
+
F+05E17"E?,98<3D.3)*!-5+-(;B#8HBF%@>)'=7@$@1;.398FC7F%?B$-3'3)/;4E>5.)H+<??#5?/$8)@226<+1//(6)H34%&?<3B@&0&,9C-F%A?#@21*B48'$:;*FB$!8'H+'6AF.%6H8E@69>&B//1)5)(7/1(*3%&?E:,&+B,
@r5684
GATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGG
+
A1#5-;$618)&3B!!)!582@!A0;4,8<)$-F2;3!2F.&-A76,''>-<&$/01'@*E$>9=/1*HE/-')#$FD.A-9+"D@;*>F7)3/4738?0=H.FAA.H5
@r5685
AAATAAAATCATTATTTGATTTCAATTTTGACCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTAT
+
>?181BF0.?A.5,FBHH%*H6H$4$(8;@B8C<5.=A5/&6?""94C2G/-3C/27'+-8?(6*?-58E5E+8$'0CG(-4,/:C3>0%A>-9'E"$D&E!7B%$1?6:)F$A53996
@r5686
CTGCAGCCAGTCCGGCGACATACGGAAATAGCCTCCGGCTCACC
+
&%2;8AHE7#,5/CCA>A;60@+A4/)79$CE:9B8'=@F>H6&
@r5687
NATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTNATGAACGACGTGNTCCT
+
,@$)3+268!-/)6"%=?D?F'!78+,8!659*=F+35C36"A@0B+DD0%H;H34&=/'4,H=G"/F>C?;<H".$)
@r5688
AANNANGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGACAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTTTGTTGCCGCCAAATAAATTGCGGTGATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATTCCTACAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTATTACAATGTTTTATCTTACTGCCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAA
+
!*%!*)+(!+)#+$)$%''$+#+!'%&&)%))((#&("*%'(*$'+&*$$!+$)(&%**'!!!#"'#&+#*!)!!&%"$*$%(%'#*'##"""!"')(&*!%)#"!%&%!+"&"$&*%))$*&#&%!&+!%"'$)%&%+*(%!+"+%&"'"$#%)'(*#'*+**&*#%$"$#('#*!!'"")*&$#*#$*!('"(*+)*"#%%#$"%'#$+#%)$#+')$&%!&+!!+&(+'!%*$*$+%#*($+&"*+%+*&+'$*&'%$"!*$&)$(!(+"+&"!#+"&+("$*)''*)("#')'&%%)+&))'$*#%'#$*)#*%+&#%*+'*$#
@r5689
CACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGNGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAG
+
%-<19&-G))"4'2HH?6;1G-5:*&61+98=)=!!8(<;*=,'2$AB'79&5G<%8-',43>&'=$)(8%BB"?>?&48528@/#3")0$-!0C8H6'E09;/')'"D/;:):5C<1EG+?F:94-/.
@r5690
TAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACNCATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCACGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGG
+
55A*#.;"57=#&-9-0G/9/(>8;/A6?CBF$@H-4;&E/6E6#!3")1,<<"A457.,!0#,8(EFE*"=<4)7F.B/)6D%0$D&!H+#'/-00>B;-AF"#;!(3";E$'5-.3%.6;#&/;
@r5691
NAANCTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCNTCCGAACAGGACGATATTGTAATTTCGCTTAATTACGAGGTCATTGCAGTAATTGAGTTGCAGTTTTACCANTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCA
+
'(*$)+('*($(!$&"*(&%")"$)%)!!++#"%!*!**%$#)'+)'**#+&!$&!'&+$*#&)#)#"!%&'#)&!)'!!#)*$(#)&*"$*'**$+#%&*(('#*'('+*"*%+&+*(+&'")$$(#(""(+**#+*(*+#%%&#'$'#%"&!')(""'##*!!)+#"&%&"&#"#("!#%&"(&+++(%+#$&$+!#%#&$)%+(*(%$*"%%'%&"!)!&()#$(%%*!(##*''!)'"*"$"""#'+'%*#%+!(""!)+"#+%)
@r5692
ACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCA
+
,";(2<+DG912,2&:1!6!.4&0!6@&-=$D$10&51HBA6AF-8!#D#38173>('6!&5#!+-&3@,H4%>>"5AF)@G"67(1*"@G/H-%!+?A)69,B.(2:2D:F&D/D<%!38;AD</,:4<CD
@r5693
CTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAACTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGNTAGTTGATAGCCTTTTGTTTGTCGTTNTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCAGCCCCATAGCAGCCNTCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGANATACATTTGGTTGGCAAACTTGAGTGNTTTNACTGCTGGCGTATGACCAAAGGAACGTGTNCGCGCCTTTGATTTCTT
+
60('+1.C;7!25<E),4.678'HG(6-(>*AA!7!,)8"*C$(?0C$<83+;2?4?5G!BC'A*7H='9<4=@C/C+(:"F&$H/F5/C=;%2"-3<9).6#%%"=$,#,G#=;CB(@B@?EB.(/#E:+>C?'>(:CF-<B!#)3ABC8D;$7HB(C78<&+7F/?*C+.9&$5D<-#(G$7CEG<6>-$B:B)24";&>E$55%1<"91(61D&6+C;;:DBB=+7D'1&E/H>5HF(C>+D08$*<(>C!&C&$8"3;#AH&#ABC%D@H*,!<72G@?)B4"*F22$G!?><?65#,)EGC,G#DHA!;46BH(@.=EE,!-%9)9-B6>B:%$?7$/</H/;H%"#1=3DF1E&//45C7;BHE,73@$H;10F6:>&)9068%FFA=9#<.EEAC20E@=3%4C(<!;088>>@(?7F?>9E-'$C-55GA.<2!)14AB>F?=GG942EG58F?#D-/1A>
@r5694
CCAGGCTGAAAAGGGCCATTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGNGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGNTCTCTCCAGAGNTTCNTTAC
+
B'2A'EH&@!7"9+59D6&,2$4?$(G&!')D,G7>"?B+:B%.;"GB5$0&//4'#)2.'=E9D8<<=!*90<8**C-E6C.%2B=,-;460<8!C>0.<2%7H5H>2B%8:#;$/)/;-&E+>79;FH(%><(*3A.-/.H9E<,F=3AF)(H!$8'C8>?9H*,?HH$+:%2A8,'A5C/+(-%7/2*F9H)!A<EFGH/+@/%<2!@C*2#1++,=1#B5.A'G-4-"*6;.
@r5695
TGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAANCGTAATTATCATCTGCGCNNGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGNCAGTGCCGGACGGCTTTGGCGNCACGGAGCNGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGNACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGNATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGANGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGNAGACGGCGACAGAGCTTGTTGAAGATACNCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACANCGCGCNGGGCTGTGGC
+
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
@r5696
AGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGNTCATGTCGTTGGCAAGCGCNCATACCGGTTTTATGTCACGCACACGGGCGATTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGTGCAGAATGCCGTCCACCATCGGATCGCNGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCNGTCATCATCACCGGATG
+
*34&&!0&4,7F0B?(6(CEB'5>&D8F'DB(<H;+7):7C=2)?.-8)<%.*>-6:-<!F&931'0E!A4G*;;*G7B/+(#72C>?CD-@$BC/D*?+:/>=3?58"G(;8:0)2DGH$?8$=+.G@<;>"%+4!CC*G+7G#/F541B35!/,4,>0%50'1=,@+B76B/1.>%'&H1;&*462)!G*H?"2-7%$'%7"?224('=G*9!4";7.&)0./&8::5"H,(D7D#"D?3D/7G9772:3@;00,B62D$1E-=60(>'<C7C3&5HD0#2<F,@#"8*.?*B;<8?35$24+3$<)1-70%.A9-5HF?$E':!@#:94!87%36.9''")(2'F4!.!#>EH.*$970F7*!*'C)A?B(>#=.:=-<=743:;67$
@r5697
CCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTANACCTTTGATAATTCATTACTATTTACTGAGAGCATNCAGAACACTACACAAATCTTTCCACGCTAAATCANAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGNACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATA
+
9=C;0@E9"E">9;B%0)#,5C81++3!2B;EE(A:G8E@%?99$G#$2CFD"BG69'*1AH;)1>!)/H5%&9=$.?(%75&B0/:.1;>@"B3!<B-2AG#*29C<(/8.A2F&EC=+CF*=725:D$2H.<.B&/%B-;"$>3;<$+;2.!.12=H%G/))?C2;A6728$F02.@&G!F78,/G@1G8,<=.A@$93DGG5#+;2>6HAB:).<8'-:5:(5;'2:@E?&5D-#+?42>82E=/2D3EG#DCF8;G.#/@0+A?BGD)*8F0EE3:40;B:E6+,.2<<,'<AGG:2#EA:AB&6.,4#>&B>B)>!"2<G1!))$DD3/@.7D!+7BE**(!'+*H;6#H9')1C@4=8>
@r5698
AATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACANCCACCGACTTTTCACGGTAGTTTTTTGC
+
CD'79G2.>1,:!2AA!>B<'!@)?'G2'D#3A$*4C5C8@=';+8F6<GC:47=*@E3E;E#DB1(-/!/"F243A;?;"H!><:(*=)1E<-"($$8$D,*/.&+'19+31$/E@6.0.C!H4945EAG=F$>!C>.@:5=A6.H%0@#G27;>E-2:!,!&/83":DA%?)G336+4
@r5699
GGATGGCGGAAGTTATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACNCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACANTTACGCCG
+
$2:>F:!B2)A$B$:?0@!-#<60.C%"0+;3-E'7"%.857G.B"#=5F@(3(+9#B/1>H8"E'79H#92<&>53%B=#3C"G4BH)?3:+H*#F$,>D?&%'H:7
@r5700
CTGATTTCTTCTCGTCTGCCGTACTCNGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACANTGTACTGACCGTACTCCNCATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCANCACCACCGTGGTGCTGTTACGTCTGGCTT
+
)@726,C>B$H@;-!32"#,G3!)?1CCG?6"E3=12!F?;&:++-#1(0>,.%&=<&HC"3@<*4>A/*:&B?$8:%9@1$?*0=:$A90,#--10=@E6DF8*C)F4:&)?.B:*862,G9C.+*#CE0#%337)&%%E/#52166))3BD3(>%'C3GF$;;(!=>:,&>87A0$7EE+0%=*3.)74>72C0.+$%:)GD'6739BC9-<"2=4$F5/"F(D4?8C76:)$48D'$0=BE/)$1@>-"/$>A/&/G/'6/0D:E6!G53=55A?2A397*%/#>$#;F"-'/+$0%F4"B5A"%5,+D+1.@0>
@r5701
TATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCANTTTGTTACGCAACCAATATTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGNGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTNACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGNGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGANCATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTAGTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCA
+
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
@r5702
GATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATGCCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACNATTGTGTATGAACGCTCNAAAAAACATGGGCTGTTCCGGGTGATCCCCAAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCNAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCA
+
*74:.4+22"G&96*1+(FA9<%;;H+&48*C(()"1.67A$)C>F28-8D70&,#B444A60@$<G?A,CG/7BD;9BB0C"6<-@>:-;C($@+<#9%?6&=9(#9,A>ECH):;C14@1"=:<)@73%@(;5)2:G/*')A*"?</,;=25(37?'51#**!2)#?18#+13H00/(7?1:163&#C#!0&F-@2-,2)A:@6&"-)D5)%H5G>//>4#/.:<@EC&%E5-#*#4G:<6,9.%%2*(F@);.C>1&'0AH)F$)@8?B5=9-+0$,7@A<86C$%&4)
@r5703
GGNGTGGTTGNCCGGAGAGCAGGGGCAGCAGGCGNTGCTGGCGTGGTTTAATGAAGGCGATACCCGNGCCTATAAAATCCGCTTCCCNAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAAGCGGCATGACCGTGACGCCTGCCAGCACCTCGGNGGTGAAAGGGCAGAGCACCACGCTNACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCNGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTGATCCGGAGAGTCAGCAATGTTCCTGAAAACCGAATNATTTGGTGACCGTCACGNTTTCTGAACTNTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACG
+
*((%%')"''%*#%)+)+"&!##(&+'$*#!&'+%!#"&$$++)#(&%%(#'*+&!*)(#&!(()#)+&*&$'("+(!)"$'+(&(('$'#%')*'))$(+!*&(%''&&(%'(##$!'+$'!"$'*"&&%#+!($$%"#+'*%&(''&)$!*%"!*&%#+*'"!*+'''*"()*#''+$$'#"++%*''!"$"%&*)($$$%#"$('%%"!&(*$+)%*&$&*'()+)*#'$*''($##)&*(#"$'*$#&#))*"()%+**(!$*%&#!'#)))"()')%((')')(!$$+'"*('&**'"*!)$)"!#*%(!&*($$*$(!&#"#!'+'$!'%#&)&""#$!""$%%%%'!$')%)+&)'$&%#%$)&(&(+!$)+))*$)("("+$"$"$('&%&+(#+$&&&)&+&)"#($!!!'#(''#"*&&#!%#*$(($#((+"&"#''+)!&*%$!)))'#"%)+%(*&&%"()$*!#$%&""+!#!+*"+")'#''!$)%!*%'$*'%''#($*"!$'%$%&+$#)#%$&'*#)*#*&##!'%('#$!'($((%!&#!&+!#&$+&'%)(%%"*&$'%#%*($)")+$$#%&!%
@r5704
ATTACGGNTCACCAGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCANAGCGTTTNGTTCTGCAGCTGGTCT
+
?$!63!:)G9*:G/BA:CBG2C57.7?:99F(A1D7FB%(1565!&#%1(*9"*B,"2C60<:&!<,?)F/>3%/F>?G<'<A;)98-7.;-!5#$<4C2?"44-FD),=-+%3!8>:/D1B><!D3!</0.:$(D
@r5705
GTTCACGGTGATGGTCATACCAATGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTNCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGNCGTNCGGGAAGCGGATTNTA
+
D34"A99-H)>/8%C>66B,1?31(<639CE,A,@H7GC%<0@?".*-F9!4=?#B:!#D97'44D'1:A2=!1&8-1C-E0;C1F-#+<?'2!-<E!'-'+$6,G=?76H6#C"?&@.#2F%G75>36@'F:=#@+=EC6)@,>A49?$7'5H9#8=)>.B#$9#$$0G7*3.#A)-GFH5!+D##5!H<-ABEH4C3'-"->47?F3:>/(6#!2*'%(B/9(090"&)C@E<D4.$#)!*!%0:;4F.79F:!<-+8*5AC95<FC/D"/=#!,/GE,,@65E+3H&754A@?D/<1*A279"!8HF5,GHB7@(4A<((@)!7"
@r5706
NGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGNCAACATTGAGTTATTTTCAGGAC
+
$((&++'(#"&$*($'!&'%$+(*#"%$"&$!$#(++''+#$+*+)&+&$$("!#%%'"!)$#$*$%$)+(#(+($+#'&!*%))'+**$)'#&%**((&#%$%$!+"(*"+$$$($(+(!!)($'!+#*#*)!)(#'"&%"!))'&)"+"
@r5707
AGGGATANCAATCCCCCAATTTGNGGGATGTTTGATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTG
+
+')'$$!$&%%*%")'+()#*$#&#&$)$*"%!+$"!$$)&'(&+"$!!(*#&$'$&!+!+%&'"+"%%&#(&)''$*)!%*)+(!!'"##((*$")&&'&)&&#(++$"*'++&%%()*)*"&&)$(""($%(!'&$!'
@r5708
NGGTNCTGNGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGCTGCTGGGCACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTNCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGATGTGANATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTNCGCTTTACCTTCGNTGTACAGGCACTGGTGGACACCACCNCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGACACAACGTAACGNTGG
+
'#$##%!)#+)(&&&)##&#)+(!!!!'%&&&%*#'&$%!'"+$!(!!%""(&#**)&%%!$*!$$!!'*!%%()$*%$&'%*(*('(%*)%(!&)%!$$"$(*"$!*$+#'"&)$'%+**'%%&!*!)(%!)!*'"'&(#'!''**%!#'')(+&"%)#!('!"*#''&!'''$(+('!+*"'!!*'+%%(#(+++++)'!)&**!&((&'%+'&++$''"""+()&')(&#!!#&*%)#)$+#*!#!"$+%'#")#&##$"$"*##*!$#!)+*+*)#!("("!%%%%*#)+#$%++"+"%(+)#%%'!*#%&*"$)!""&))#('%*
@r5709
GACTTANAGTAANCCATCTACGATATCAGACCACTTCATTTCGCATAAATNACCAACTCGCTGCCCGGCAACAACAGCCAGTTCCATTGCAAGTCTGAGNCAACATGGTGATGATTCTGCTGCNTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCG
+
%)!(*)$((""#&&%*&'"''$+*$)#&%#&)")#'"*))&'("+)+%+++'%%%*!++%*+!'*$'&)+#*(*!*%!$!((+!)+)++$(!*&#+'"+%*)+$'+$&(&%&%$''%%)!*!$'&)+**%"#)$)%+$$#)%()'*$&#*#")++##%+#)'"!*"$"!#$"))*%$#!#&#!%+!')'
@r5710
CGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACANCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCAACGCTAACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCANCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGC
+
,'.-%?!D<-%#,3&;;>$D,E,=G58%B&B!*81EF%/%@+.C)H?G+1%!9A>@,F.0&?EG=2A/8CGE3A5$.31&0!9!;":6,;$D7$<:)E(-":*"70@53D5=(4/D-+;>#%CA2/1<D"1+A8B8$@5AA!:50=%2'147C4:8+2C)?G#D%!3"E;8=!54%>/8+@!,-+&2:/-G8+'1>+2'+)8((;55F
@r5711
GGTACAGGCATAGCGTCCTCACATTTCATAGNTAATGCCATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGNCGCTGGCCANCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGTGCCATGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTACAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCNGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCANTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGNTTACCCACCACAAGCACGCTGCCGCCTTTCAGGGATGAACGCTGCCCCTTTTT
+
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
@r5712
GCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACNGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATA
+
=C:D(5-#)E"#A6#E$4@,#$DD5/<1H"!*)::=<:2..501%<@4/*@E!8>B)A@6/."/<#@>B7(+.C:#1/--!'3!BGGA$#'A1?8B1H+$A2@.+7>*@8E543@
@r5713
GCACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTNTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATNCGGCGACCAAAGCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGGTCGCCGTCGCCGCAGCAAATTGCGGCGAGATTCGGCAATGATGAACCAAAANAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACNTGATACAGCCCCNTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGACAGATGATANGCATCCCGGAACAGTGTGTAACAGTCCGTCACANCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTT
+
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
@r5714
TCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCATG
+
C9+'#(9"9+*-DAB$$#13?:4#*&F&-;%0";1?E5/)*:?;4&E%46$8E=&;9H+'?86&)8H=#B$H!#+"%"6EB,"<A@<@"'/!0C14B(@4"5+&7F;H'%.3,D>1;D>,:5,:7#$*',F05F01,D/;*3-B-C2DG+*50'9"H3FB@=#;">AHE?97"?:<;GA'&#.B?'!HE<'2ED-2'%.G?;$$.B+!=-E>%:6//H<??*7*/A6&#D3*/(3?$%4-;).F3;@
@r5715
GCAGGGGGGCATTGNTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGNGTTGTATCTATTTATTTTTCAATAAAT
+
94H)C6F@DD=F;@0C'5*C#36D"&:-C=;C,=7FH(1"4.4<8C5F=E9%8C6A(("C)H.;209'>*5=2%1A/2C
@r5716
CCATTGGCGGGGGTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCANATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGNCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACNAACGGACAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAAACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAANGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTACTGTAAGAAAGGTGCGCTTNGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGAGTGACGCGTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGC
+
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
@r5717
GCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCG
+
CB%D58>8<#,8.D73G?'1E19%5;2*("&4C?#<*"19'FBC*)?9E"!19(F>"?F$>-F1D+66(@5E3)*$@E.5F:C2010=
@r5718
TTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTATCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCNTAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGA
+
F388A14<&(::<F*%'$!'-7.7%0;=42###'5@94"1H>7D5&)4=)FD*2(&27/#H+CEB;<F=:1%'=)/=2?H2(.8#)4?+GBA456?4H#4(H"F2*EF-,EB#F$1>0@2-A'#<-440;DG(G"?6G25(?-(8(-D93)>:;G)5#A.4F,4@0(H"E,&373#*A@.70*G'1$8E;'3$$>;4H;4G%:9F%H2'><'*;F;%'15G(=&2,H=+B=;F+-@F,CB#2C/
@r5719
GGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAANCTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCNTCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGNTCTGCTGGGTATGCACTTTTCCCGGCTGACGTACACCNTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCNTCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGNGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGNGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCAAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGGGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTNCCGGTGCGATCACCCTGCCGATGGTGGG
+
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
@r5720
TCCGTGTTTGAGCAGTCAATGCTGCGGTATATCGCTGCCGGGCTGNGTGTCTCGTATGCGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCA
+
25=9/0&?'6C%>4-+2+D?.:G7#$B.B45;.+##';:++<@<G<3)9&($=;=E<G?E:>2<0(&6<6!6D!9$2**#",+<147-$":1#1%F+C.B,#):54D+.5;.8A*$##!7B%,.78@#=!1E%/1)GA*EA>1G632(CHC=:89-@H@+F=;D?,0FC/;#5:)B"B"/38-6<?A4&/'/CF=&)9"-E5&B%
@r5721
GCCCCCCCTGTTGCAGCAGGATCAGCCNCGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGCAAATCCCCGCTTTCTGTGCNGCCAGCGCCGGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGNCGCCTGACTCTGGCCATCTCCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCG
+
7"E-D4&0(219?.F-@2<6@C/%2"H?/=(:E0$2;0627=!864H2@=!C,,>"$19<B(:F=A:""/87BB-$'49H6)D/-9'DG96B?D':E(!(!%0:>@<=;#!99H6)>HCF*>5G9$'D'8&/*7F%:GH?&7D=;)#0!-0G5:H&0<25,B-97)9(,!66&4#CF472H656,<0(;H-.)'<8<%DC+3HFA&%>%1)+/DEA@:5%#).2=.#:#"C?!--!=70+8F@-,E:F+=:31!)@4?0A@?"!B(!G69#2C@*G5(0@=73/,
@r5722
CCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGAT
+
:=>4D70G=E31&2&3(-AC>:;$:D!/+,6!E6=>7--DB(#2G183/35"95
@r5723
GGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGANAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTANCGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCT
+
C.,+G;;643()/-"79%#8?(@H3!#&'.#(A%>),@@,62=/-1+50$F/>C1'8>GC&H/.5448H$,)='/8H"+81..45),(03-..07@4;A5.<*,GA-201:@B6;<'G8F;6#6A*'&9HHE126%9B8)!#>H+@G6<EE@$@ECD*(C'#9G%'&00B4A<%14$C+'E&8*77?<&$"9F#@.3;/&8@3/4&.15?"*EF6DA!7'<7FC#;4>GAC,C?C&#/74"C0!>%H?#3<2+B.H5@E
@r5724
GCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACA
+
C(?,F-/*/H>B&>)8#.73?9H0$;7G:6A*5%311>0%2
@r5725
CGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATNTTTTCCGCCCTCAGCGAACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGNTATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTG
+
-C.!>8=#;5,=F6B@&A/')0D=75F?$-..1:-0EA'=%&2)8<$%G?9E;97G/!?:99(1'C;?EE3>A8H@4%$+)&#+=#<#C+-(4/=(4=::,>&/.(%:B9>BC*)5/6C2G=E%6/6;*+8A,$(@1!1);:?,F4%3D%56)6A(@$+G,D,A+3;A=!3F2-:$C=C?-$)'H61C;H)&"
@r5726
TAGGTAANGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGA
+
!4"%3B?(-4*:F1&!3/.E>;8;A'A4/(F',$2;9EDG3!H6FF692:A?2,9
@r5727
CTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCNCTCCAGCCGGACTTCAGGCC
+
:4D=H?.?GC'7A7-C"-0,?D??#/,71"BHB(>:E<",65C*,431'0<-#9E93>954'-&0*FF967B5+D.(#().(5-:-$5F>>0B#HAE;,0;AD$,(#A8(?7F@@94*<#8D=,((EA.F66C.*-3(,90!1
@r5728
TTCANGGAATATTTGTATGCCGANTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGNAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCNTTGATACTCATTTATAAACTCCTTGCAATG
+
*)&("$+%!!()'&'&+%!"&!))"!+%+)+#'%*!#%)&&(!"&+&&)')!%&*%##+#!#$#%%)*&+"#%"*)''**"#%!(%#(+"*(')'!(++"%"&*$(+#*(#!!*+'+(+("+")!$$*'()%(+)"#!%+*!%!$$*&'*$)(#+!$%+*$("#"!%*
@r5729
GTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGNGTGGCATGTTTTCGTCTTTGCTCTAGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCNCCAGATATAAGCGATTTAAGCTAAGAAAATGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAG
+
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
@r5730
GGCNNNNTNCNGANCGGNTGNCTNGGNNNTCNGCCTGAGNCTGNNCCCNGCNNTANNGTTNCTCCNTGANNNNNTNGNNNTNNNGNCCNGGTC
+
!#$!#$"$####!!!"!#$""#"!""!##!$!$$$$"##"#$#!$$$$"##$$$$$!"$"#""#"!$$#!!#!!$!""##"#"!$""#$#""#
@r5731
ACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGANGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCNTCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGTAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTT
+
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
@r5732
ATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCNGACTCCGCCGGAGGGATTTGAATCCTCCGACNCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAANATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAA
+
.0,-2#GF=0EH543#$6#;<9=;E&@&-0>C2E<$9BH7"B$)"B-4;8B;-2'?C$*:H)2>)/>7#B'"@(94$>B-8#&8%F08G@>93&-$(:$!G7F<!/3'%DC%!@%C,$&!!C"F$97-14:B36&26A>515#-6$D3?)A(??H183)7H49-2B06,3?;-'!AB7'.%6;!?811FF(AH%E:9.-1@CC<;7!+@B'"@@#=<42':.%FE"B5)#;>9;9;,6,-3'836CB*D3G!39CE//)!%*09H.3C@"B8;@;C*DB=3E3)57HH5%=D929%0"C9*&;6/0*C=.AD,,B?4%B"6?;-0<3F-DD>+(A%1'%8(*%/=7::@'8!%H(G2,E+H&31DB908B0(8ADH0H0)2+B/:,;2G?2D.$:7H.?::;B)0E($18-&@*+:7#3+0<;69?ED0<8C6%4-5#39E9#%53C(:3&#*.A)>&9(3!-4&7/E?.E2A,@2@G"B":
@r5733
TCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATNCTGAATCAATNATGTCTGCCATCTTTCATTAATNCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATNATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCNGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACNGGCAATGCTGCGAAGGGCGT
+
+%'$$++%$'%)$%+%(*!%)*+(++&%*!(+*'&&'!'&!%&!(#')!&!%*%#%#!+&(+%+&*#'#"!"!)#&(#&"!##+"#$(&%'''!+'"$#*&'%!)('*($*')")&)"*!*$$#$'+')'!+*$)#!')''("!+*%*'#%!$*(')"+%##)&$)'"+%*!%#*(%$!'("*#&#'*)!+"%+!!#&*$("")*)!('%!!"*!(('("!*"!($!!#'!+%"#+(%($)('$#$()!"&$$$$!%#&*!!&')*&*"''+%("'*&"*&!+%#%'(($!$$+!!'!%*$&(**#+$'*&&'*('+'+)#&#+')'$%&&&&%%()*&()"+)+*($$')+"!)&"*"$+%"&%'"($#+")($"!"'''*"(+)*%"'!&!+#("+*+(""%)&&'#&'%+'&*!$%)+"*)+%!+(*(%'"$"*")$!+"()&$()$"&&&(*$)+$'%%*
@r5734
CGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCNACGAAAGGGTTTGATGACCAGACCCGCCGCCT
+
().'?$>/#=>E@%6@"2/48"=)7::<>:A4)-:G#65@<3+H+3G6''35+D?E$*1"BE:CE</-!"/E.)DC)4"?:6A'>+,70G9*6:>1BD.@H6?9B377!'F;D0D@8-#6
@r5735
ATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGGACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGT
+
H'@3#&205.:(1F;'5C%3);:!8!FE<7!E/3%'=0>*A?H<AC&%75C&6E647B4");*844@<8=/=,D.#50C90H&=/40"13FF8"HB%-"BF(#G'4H$/DAG'&(>.$7F+)44.83424GCE37E/B+E84>,;98H#51D62(.39=AF.;7(:@*9C+E$B*1B$G::2$/?!#@.<0;5(;7?:-F83F(<ED!*E('4&0@!0/1;0.#9?)""?C40%&,,E<(*%B@G20:C#484=&472?=ACD>0:G8:%;!03H-#?C/?4H1,&=+#E.*A:-3#H*H!8@</'$D=-61$)2;#6B%<3$?)6+-/2%(B(H9!83!4&0D0D&(?A=5<:<%/;!C(>@,B&7&#3
@r5736
NCTTTATGACGTAACATCCGTTTGGGATGCGAATGCCACGGCCCCGTGATTTCTNTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGCAACGCAGATCGGATG
+
"*A':#0E(HG>3*A!FH-%!H!**&9?0$2:";G:4ED=@D'#8?9G64@4$#E#!($#3#1G&GFB188>0<&@A29H;5(E('H%$HE@B+".'D3>40@&71.3=+03:H>5-)$$0=
@r5737
ACGATATCGAAGCCTACGCGNTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTGTCGAGTGCCTCATTGCGTCGCTTTTTNCTGTCCNACAGTANTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAG
+
@H@?:#E6;'H(&)&B8'-*.'3,?H&=1#)113%:-D$6"%;+8<7=9/90/:A/;-%5@5&25AE4.9(F(/1D")6F3F@-@F+B;*?3?<5@$@>#$-&>*?.B9?5/?F'+.@.B//"#'%(+!(12D9BHD6%64D&*;.%E4,3E3@CE6D*>)
@r5738
NAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGT
+
%FF1D,F;"96>.8777G#22'/0D8.$H0A#!+:6A=!5,G%8:73DH871*=:G8&BAD)
@r5739
TGGCGACGGATTTCGTTCACTNCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGTTCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCANGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGNGTTTNGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGG
+
'D&<D:9)&!H))=6<756(199E.4-+&H@>,**1+&*!(+8<&@)G*((<1&99)G%5)5'-.%0#)A/8!E>="0-!&57*/-EA@4"0;()03:!+E=DGF&9(03B'<"0AE/*?&@;*$.7=/'HG1.*>3--D-26;&(81GDE.3)#-<);A4.-=H$%)(HBC!*;1H>?"+=(&B7F%9B"E*)+0A/96%@(BE'3&3-2/8=7F@#%<4H<,3,%H%+"8H3@9G&G(8,*E;$8$"A=/0DC?=/4,97:G&DG,G>7<0<?#697,F-48>C';E83-21/?%+H<C@E5749*D37,%9&&H?C?@$"4007/G/G6!>;21AH(<H;$A46+G37G?F3G:(1E0=.A<
@r5740
AGCAAGCATCTACTCCAATAAACCAATATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATACAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGANGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGANCAATTGAGNCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTCGCAGAANGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATCACTCCATAACTGGGACAGCAGGCCANTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCNGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCNTGAAGCGGCGCAATATGCTCACTGGCGACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGNTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTC
+
))'++%'$+%%&#)#(*#%"%$*#!'+*%#('&$(+#&'(&)'")')*#'"$+(!(+&*!(++$$*#*&*+)!$))%!(*%%*!'*'!)&+')&%(#*((*$*"*'+$#!(%#('&))%*)()!&'"$"++#&")'&%("*'%)&!*%)!&!&#(+%*(#")##("+$"!###*+$&&&)%&(*'$'*'()+$)!!)&)&(*"+"")('$&**(++!#&*$!*'*'(!%($"#'"'(!)"%)#)$($'"'#+$+!'*%*$!*&()&"&#&$+(%+#")"+()#"*+&"+$+#$*$'#(*('"&(+*!'+'(%&!+')*"++$*#+$%#*%$)($"(!#!"*#&('*'"$)+%%(#$"$!'&#$"%(#+'&$"+'#+"'(+'!''+)%)"%!#!+!&+%!*!%$+'!'%'&'&(+'$'#!"%#!'%#*%$*!&'#%)"'%%)$&%'#*()'$!)!+"#)&)$*)$!')%'+'*($)#&'!&('$(("+!"&(%'$*''#($+'*+%"(##"%)"+*((($%$&")'%#)('&("&!'"(+*&!"!$%+*'"'"&''%"()(*#")&$&(%"#($&)!*''(!$"++!")(!%)"(!%)$'$#!'+)#+&!$)!+!+!&'(+!&
@r5741
NAGNNNCNGNGNNNGGTNGANNTNTNNGNCNNNGGNNNNNNNANANNNANNTNNGGNTTTTNAANNCNACNNTGNNNCNNNNNGGNNNTNNNTANNGNNTGNTNNTACNCNGGCNGCNGGNNNTCNCTANAAATNNATNAGGNNTNNTCNCGNNNACNNTCTNANNNCNNNNCATCCNTTNTNNNATNNTNTTNCCNNATTNNCTGTTNGNNTTNGACTATCNANANNCATATNNGTNNTCTNCAANNNCNNAGGNTGCGNNCNNNNNTGANTGNCTNNGCNNNTCNNNCCNATNGNAANNNTNNCANCNNTCACCNNCCTGTGTNGTANTCCANTGNGATNCTCGGNNNNTNCTNTNNNNNNCTNAGCNATNTANNCNANTNNNCNNNGNNGTANNGTANNAAGNCTTTNGTNNTANNCNTNNCTCNNGTACCNTTNCTCGNAAANNNATACGTCCTTANCANGTNNTATCNGNGANGGGNAANNTTNNCNNTNACCCNANNANTGNNTNNNNNCGNGGCNNCTGATNTGGNNCCANNNTCTGTANGNNTNCTTNGAGNGNTGNGNTNNNANNTTCCNGATNNCAGNANTNNAGCNANAANNNGTGNNNNNNCGNTTAACNATNNTCNTGGTACCNGNNCNAANNNNGNAATNNNCNGCGNNTGCNGNANTNNNNNANTANGTTTAGAANGNANNNNTNAANNCTNGNCCNGNCGGNNGNNNAANNAATNTNGTAACNCGANGNATAACNGACNTNNNGTNGCNNNACTNNTAAACGNATGNNGNNNATGGCTANNNTNTTNNNGGCTNTNNGGCATTACTCGNNGNNNNTNTNTTTNANCANNACNTGNNNGAANAANNTGCCCACACTGNNTGNATTATNCANNCAAGTATNNNNCCNNTANNNNNTTAANNNNAGTANGNNNCNNCNNNTTACACNNTNNTTTANNNNNTANNNTCTGTANGCGNGNNNAAANGNAANNNCATCTNTNNNNNGTTNCNAGNNTNNCACNNNATNTTGAANNNAANTATTGNNANNANNAATTNNANNNCNANACCNCTTNANATGNANAGGTACNNCGNGNCGNACNACANNANCNNNCGGNCNANTCGANNAACACNTTNCNATNNTNTNACTNAATGNNNNNCTNNNTNCTTANNAT
+
$!!$#"!$$!""#!$#$"!$""$""###!!!!!""$"$"!!!$##"!!#$##"!$$!#$"$"$#"##!$!##""!"##$$"#""!!!!""$$""!$$!$"$!#""$"##""$"$$""#"""!#!"!"$"!#"$#$"#$!$$!!!"#""!!$$!!#$$!""$"$#!$$"#!!""##"$!#$#$!!#$!""$$"$!!"!#$$$#$"$$#""""!!!!!!!$!!#"$$"#$"$""#!##""####"!#$"!!"!""!$!"!$$!#!!"""#$!"!"#"!$"!!$!!"#!!$#!!"!!"!"$$$!"!""$#!""$"$!$$$""$$$"$$#"#"$$!#!"#!!$#$!!"#!"$#!!#"##$$!$!#$!#$##$"$#!$###"#$$$##"!$""#$!#!$"!##$"$$#$"""#"$"$$!#$$$"!#""#"!$"##$#"#!"""$!!##$$""$$##$$$$#$$$$$"$!!#!#""!$"#$$$#$#$"#!!$"#!!$$!"!$!!"!!"#"!"$"!!#!#!!!$"###!#"$#!$!$#"#!"!$!$!##"$""!#!$!!"$$"#"#"!"""!####$"!"$!$$$!#!!!"#$"!$""##$!$"$#"!!!$!"$!$!!"$$"!"!"##"#$!"!$!!!#!#$!""!#"$!$"!"!!!$$!!"!##!"!"$!###$!$""!#"!"##$$#"$##"!!""""#!"!#""#$#!!!#$!#$"#"$"$!##$"!$$!!$#""$"!$"#$$!!"!!!#"##$!##$$"#""$!"##"#"###!$$#$"#$!"#$#!"!!$!$"$#$"!"!"#!#$#$""!$!$!"""#$$!"#$$$!##!!"!!!$"!#"#""##$$#$!$"$!"!$$#$""!###!"$$"$!"!"#!!#"!"$!#$"!####!$$$#!$#!"!$$""!!#"$##!#$##"$#$"!!!#!#$#!!$##"$#!!#""""##!$!!"###!##!#$#$#!!!!!"!##"#!"#$!$#!"$#!#!"!!!!!$"!#"!$!!#"!"!##"$"#$$#!$$#"#$"$!##"$!"$"!"!"!$!!$""#!!!$!#!$"""#$#!#"!#!$$""#"#"#!$"$!$$#$#$$$##!##"!"$###"$!#!!$!$!$!#"#$#""#""!!$!!"$"!!#"$!$##!"!$#$#$##$##"#$!"!$#
@r5742
ANAGGAAAGGGGGTTAGTGAATGCTTTTGCNTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCACCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCNATTCTTTGGGACTCCTGGCTGATTA
+
*#*-5:36/D@')#28A5".A9A>%85GC'3G/@':"?!C>@?3C."%/8%%HB480>4>CG$))>@AF)?#D>&H/F9>-(G!EF5+DCGF$*3'2H'$%.?08"G+=151EC"BGG:+:@F'H*/"#7$DC.+(.(B.D%#6(3&19*<1CC6:0+6#"#(661:%=%GHB'H0'$"-
@r5743
AGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCAGTGATGGCATTCTCTGGTTTTCGTCATCC
+
.<$)5F)5,G!*77."@12C*H<">&=$&$!7;E//;$-43B6E(-9&,,71D28&>&);/':#';>3!.7?/#B'?1%""#48DH32,=0A/B567:799A52@2AG')=3$=<0'7'&H)7FH&D$0=$=?CG#=&&682B'%E>$=+B-7&$.8GG+6:/7H9A+C6F=(D=
@r5744
AAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGAAGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTTTCGTAATCGNGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACATTTCCACGCTCTGATAAGCCATCAATCATCANTTGCTCATGGTTTCCACGTACAGCTCTGAACCAG
+
265==18%>%:B&%1,#82,G8"!7'1#E@'H-!:G6E=85/@AHD8GA24%8FB,6A61!8$H13H9,>!?8$&:/%D%?;BF3D%,9&?BGA36*/"4?)9-':D@?1+=A7(=?(+.E6A$18B43*21!!86'@F-81%.$?<,(:DGG;D60D'F/3.-2'<B&-28..':!.:5+3?9:&'<G-06?8C6G>-=-,H45.E1"6,!0H6"(4*#5;=10A#!.B-;:<C13':8H&0HF4(
@r5745
TCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTTACGTGTGACCGCATTCAANATGTTGTCTGNGATTGACTCTTCTTTGTNGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTCGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCCCTGTTTTGGCANTATCAACCGNACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGGACTTGCAGTACCTTTGCCNTAGTATTTCCTTCAAGCTTTGACACACCACG
+
%(&)#:13>4(G8E1"?.%CG(H$0,0!90501?@'&)$G/G3B&)1D(A6&H='H,C3G./E@!H4<"DA2*4@>D-HA:,D5$$C,"-2%%3),0>$+#C#4):5>1B,55#C%F@>1'<"+%/,AF+.46(2;@%)2E#4%5@'B8>*E8A+)%'/29+-)6%002!:)A?8:+8+"3@;%&<3">H,E,&/%/0(+3@+6H$D(+F"<!'G$2#0>'50,E7A;61*#$,:*G4E=<C,<3&&?A&%',%4)35F79*!H%/0#/5F10AB,/?.60/$/2='/;)G7%,%;FEF#?8F@>$A;A62A85B#73-2?A&A@+G4'-!)8C$-D=1DC86'0DH=CG!.7DF:@/=9,'9F.F@:8?FC82@+,8!4F19!F=*9GF:&':#G$7,;77":!,(;@#G%5/$,60>.2
@r5746
GATGCCCAGCGCCTGTTTCTTAATCACCATAACCTNCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACG
+
.89/3A4298--D)'%>*%05BA"2B<$E/&A97*B.615,@1>9E.2:<1!+;&A$?76+#66%84BEA#?'%>C)8D.3;6!=>B0?
@r5747
ATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCG
+
F/A)5>C+F/=($(@1</?#%.##")D(/=C1?;28+4C"3+=#?4@D%*8F@0-6%H'=B4=8.912?),B:)H-EH;;2)/FE2.?038D*%6,8&2C.($5;F$@)7#7F>"+"F
@r5748
CGTTCACGCATCAGGCGGNTATCGTTAGCCCACCCAGCANAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTT
+
1"/G2*H=#'2'2DD<(@2@2.!#482/$7G?=8*9;1<F!"=56=%5180@?:@#@F#)-'?=D$"-B0"%!7!CF;2F<G;#H6*3?9<+#B?9FHH*"(04DA1G)-3/#5C:@:@++16:'BH)D89+G('>'57;"B0%:CC6<B@9G86E".
@r5749
CGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGAGCGTTACAGCGGACGACGGCAGCGGCTGNTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGNAACTGGCGCTGGGGAACTACAGGCTGACAGTCCNGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATNGTTCCGGATTGCCGCANCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTNGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTAC
+
:$H5+((BE7'&/(577CB4$9H":'!@878%//(6)D>;&H%('!4272<=:;=3G?D25?6-?&23(@/DED""&G'21EA,>>1'?;1@=0CB99!;>B2FA623G')B>0B8=F(<5%5:<?G#5>5323'6;+C%"&EF4*E2;C$3..52GF4%(906'G*BGH0:7FB:.+C'@(==$H$(=*H=G;G;4A.6:/*CH=750<=E"&7*F1B>()>%H+9>FH906?&B3D=HEA'F!,C0G'7$)ED&5%331GF=1DH,0B2#3E)(&1/<4&,5)7A'H$,%1H/,3+%5'-;'$6?"#?3>)'")4%!70ABH4FH/1)@E(">7;)5G,&+@(%(E#@A<"D6D6-1H0!9$7,6E80D:"9$391@+<)H2B516&$0+G(@%4;/'5EEG7BA04&0@31!4$F8>G8G)$(7C-:#F0>/01*;;F4=H7;(#08@6"!&
@r5750
AGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGNTGGATATGGGCCGCAGTGAGGAGAATAACATCACACAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATNGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCCGTGTTGAGTGCCNCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAANCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTG
+
E:.B.54>H3924A!/388>328@B9*2*&;<1;$E:=<DF3:"F1$%,%';</*B6'77.!&G.)#D7/47$D12B4-1'@.$)?'9-4#'.<7(!,.?/.,D48'$!:&G'=H#9(E+5E0E:&<3&*=/)+90.,%#;GF7&C(9@-&25>++E,41".)$!9A.56BF0D:C?;*A7%=2"/*E)>3$-9C7H#B3?;>+'7##G?8.?5A%&E98++*&3;A&F@@;D871H$=(DC+6<+0B@=A<55;<$,%!:>/E88>AG/.(.,H-,);$&HB8#4C4F@7-6,7$.?D77:<?<HB%DFG''?!8F%!>7##F9=C*H=+<6B-G)&<G(7:5'F!7)8".=4-)EBA5,?*5%95.F(#:&$-&;-**CE%636"&>?)>'2>?;C&(H1D;%G"=$H'&G$C**-.GB?19"2=B<0=%0$7<@G"9@?,0H:4;'68C+!12;F8=,?0<+%H8.4,AF?"E+@?37=<!E>)
@r5751
ACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGACAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAG
+
/"#65$C$7(=CCC%D0<!4%"*3*1"C7H4('&575%(C.8F5=,/D+E86D/.C);C#<1'$8;'%*@*:G7C*H-,H-7=%#F>%)(>8H;&?52H2&'#0+7769G/5$$'//=)$@#H3D)3),(0@C64-3DG>.:=A?/<3,(8.+%%?.A%6*%A)C5@$'".-'A*CH!%G7B:"G>&;*3=>:1G=9E/+2#E92!?C1&"D@A5A9'$$255+.':&F1/%(>FC07-7/@=@'3"=;0/DEE@*&4,A-%
@r5752
GACACGGAAGTGGCCGTAAACTTCNCCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCTGGTCATGCAGTGCNGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTA
+
DE=;&9.6=A6H4E&<>803/8F!*!".<F@F-?)<60&43,=5<8>DH8(A/D2?#=*G#$:04B+@075,#)1=D,"14$(00%6?F)9D$/%#463F9C*C"FB0'=&B7H,/$G67';.9/3$.5"2!0"B.!&,-?DC$&"AG(19
@r5753
TGTCCGTACAACTGGCGTAATCATGGCCCTTCTGGGCCATTGTTTCTCTGTGGAGGAGTCC
+
.>?>E0B:-@.:27+9*C%@/#F30A*'/@BC*:!49,0+=@1-H5&,A$1#%<:"#(:GG
@r5754
NGGNTCACGGACGCGAAGAACAGGCACGCGTGCTTGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCCGTGACACTGCGCTGGATCNTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCAT
+
!+!B"@5,2G6785?&@G7@@54$DE$-!.47,%ED33/BG>5C$C%G&%G81AA$#74D91B4;279#8+=HG+%1E-$63500"8.#&+#;149&)52!581!"F*CH:?<F+-:2)B?H.@",'5,<B/))'/*8(F,0?8#>?B,$:+&"99D0>22)*;A,'HB4A-GC7CG
@r5755
GGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATNTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCNGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGNGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCCTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTAAGATACAACGTAACGGTGGCTGGGTTACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTG
+
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
@r5756
ATGACAACCACGGAATGGATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATNGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCNGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCCCATTAACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCAGCGACCTCGCGNGTTTTCGCTATNTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCNTACCATTCAGAACTGGCAGGAACAGGCAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAATATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGNAGAACTGCGGCAGGNCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACNAACGCCATCGACTTAGGCGTGCGCA
+
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
@r5757
GTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTACATTGCCGTCGTTGTCGGGCGGGGATATCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCTTGGNCGTNATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGATCCGGCAGTACAATGGATTACCGTAAGACNGAAATCACTCCGGGGTATATGAAAGNGACGACCACTGCCAGGGACGAAAGTNCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGANTAATCCGGCAGCGTCCGTCGGTGTTGATATTGCTTATGAAGG
+
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
@r5758
TGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTC
+
%=04!1/"2H,DG<,,-$CA!-BB.%B0-A&:H248)G6!!$@4?6A2G&'%2(":
@r5759
TCTTCGCTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCNTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAAT
+
E4&1@'.DE@-8>)!F,G(1F>23&&$'*7,71*(3+.F?5#'1-*?%(22,,/:!DFG.*+BH2,E64<@&'#%"6$+E-75/3G>3%>6B0@G0,:+-H,%9EB;C2:#87E'>E>%FC0*("$>D$+(4%=+C)H!H!73+=1C$:#B/"5G0<EB+@6F
@r5760
GATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACA
+
8"&,*'!")?F)2,;'F<10@)+1$#2&<C=0(B@;;.4.(?6+,;1=7$67!45D"&+
@r5761
CGNANAANCNAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGNAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGAGCCTGCTNCAACAGGGGCGGCAGGTGAAGGACTCCTTCGNCNGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTNTGCCTGGTATCAGGGCAACTCAANCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGNCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAANGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGCTGACCACAGACCCGACGTCGGGGCTGACGGAGATGGCTCGCCAGTTCCATAACGTGTCAGCGGAGCAGATNGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGNTGAAGCCGGGGCATTGCAGNCGGCGAACGAGNCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAANATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCANAGCCATGTGGGATGCGGTGCTCGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATCAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGANAAGGCCCGTCTTGCGCTTGAAGCCGACCGAAAGAAGGCTGAGCAGCAGACTCANCAGGACAAAA
+
(*%'("*#$*''&%(+'*!*$!"%#&&#)*!#'*#!&$(&''(*%'))*#!*)*&&'$#!'*$+(*!#%*'$!*)*!!)!"(#+#$"'+%)#&$#+#*%*&#+)%)%#%$!%#$(&+#"%*'+#(%$*+&%&(!$$%$%*$&*%)+$%"!*)%$*#"'('"(&"#+"#!%%*%"'%&"++%(!#)))')&#**#&''&!++$"%'#$'###*("!*%('%*"!!&+('!*#)#)(*%$"(%#&)!'!$)'($$()"#%%(+%"#%!!&#')")$+'%!+#'"!+##+!+!&+$*'!!(&#()$%#&'&*"("&*&%$%##"*$'!()'("!"**)&*)'%))()&$"')&'*('*(%(#!'*'!)$'$'"($$&*!'!$&(#!'*!"(+*#$+)&&&%&$%*!'(&*%&(($"'#%#(%*)(%)"+$+*#!('+&")(*$*+%$)$&$+*$+$!*')#))$()&"%*'+'%&""#%$')$*!'$*&*+"*)#'*()!*)%+'#!&''(*)'+%#("(*!$*)$*+*'%+*'$**&)!*'(!&))('&"#%'%"!%)'"%!""+("(%*)**(#'*$(!*%'*(#*(&+!!%$(##%*&%$$+&%'%''!$)#*$%#!#"%$#&!*#)'"%$%(''(%)($+'*!$("*")++$!!++#!**%$++&%##*%*($&&%"(%&("&&&!%'#!&*&"*"'%!'(+$)"')&$*)#*")*&*&$*$*+'!)#"$$%*$+("!(#'+"*++)($!**$'"*(%!''$#&)&)!#!+'%'!)%"*%"")(##"#%%+#+)&%!!(%#!"'%'$"&!(')#($+!$&&)#''"$+"$*+#&)%&%#)!)!)("%"#$*&!*!&')*%')()'#$'!(&")&+&$&*"($#)!"&"#*'&)($%%#)*$&)&&(!)(("&"!)!%#*)%$')"!'(%$)'("+"&)%&*)$%'+"!'(*"(&'(++$(#+#)(($)#"&!'%+!*+)!$$'&!)'!&)!&(*"(&!$'&*%##&($"$&)*''"(&))*+%+&!+%)*!%&(
@r5762
ATTTTGCAACCGGAGGATTTACGGGTACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATCNGCGGCTATGNCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCG
+
+$"!#"&(()+)+&"%)$$&')*+$))#)!)*$%'#*''%!&%!%!$$(("&'"#+#'()'$!"%)&'*$*%(+#*"($$+++)*()"#"++#'%+#&(&+"#'((*$#+('+("!%""'$*)!+%&("#++!#'*)+%+"%($"%'&"!(&*!#&%%+*%++)'("++"+&())%*%$&*&#"%!"+"++!%%&)#
@r5763
GCCGCNNGCAAGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCTCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTNCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCAGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGNAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGNGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAG
+
''')'&%*%%*(+"+$'$($#!#'+*%(%##"''*#"%#!##"%*'+"&#")'(!!"#'&)(*('&'*!()&(+%')!'*$'&+'*+('&%%%%&"%%!)&+*'$)%'*%&"+"$*)&%$)'&%)#"")*!&)"+%$)!&'##!&*%"'"'$)#%(*)()+'!&&)'$+#&()"%)(%$+*%&!#""+)##)(#!)(!"$)$+%')%#)%&$""%**(&!*&*"%$$$+"+)+%')''%'*&&&)%&!%$!$)'!*)+!#((!"*!$'"#'$!%"))+!*)!#*$%&(%#!"#+$)&)+&%&%($%*'!!"(+$'$+'&'($"$'*"$(&)+%((#$+'&!#"*!(%%)#+'++%&%"#+!##")$)*%"+""+$%%%&%*('(#$(!(''#"%"#+''$*"'*)&&$+*)+&"!(%!*))&!(##%'&%)+&)#%(')!+"#+%'+$')%%$'*"+*'"%!!(&*$)+&%%($*%")#%"')(%$+'+#%)%&(%#
@r5764
GATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCGAA
+
28;C*B!D9E1<0;$>0,@D#CHFF+=&HA<*F6DAC<.&*57,;34C;/H%<<)61!1%517AC),8F&18F2E/=(0"</D83294G=4ED1CE&G*=;@/2,;6&/<75:6F$7)/AC";#=!9!C!&2CH.8D24*6G+->'G(.'&D*)(<70%78>*'F80
@r5765
CTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTAGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTNAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCNAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCCCTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATNCGGAGAGATGGGTAAGCACAACCAAANAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAGGGTAATTCCATGACCGCACCAACAGGCTCCAACTTTCCTGACGGAATGTTAATTCTCGNTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTNANCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCTTGAAGAGACGTTTGGCTGATCGGCAAAGTGTTCTGG
+
5B!A-B43$";"C%1/<0=#''(>BG0C"/F#?,(=00>91!AB1"3,1?8@0&H6%A82!H4;7,&?'!G&/;"/13:1=4$$2752909-G&HGGA"&24?!'68;5%.B2=>19'HBDEC&>C$:C7B7#2'@E/EHC2)06$0:=!FG1:&1))G'(4=?*"4+#3,89$+-G3+12=-,$G9#(=3#&(/,7D0E65C4C+:HAD$H=&E0832.E)$)D'8"1>5FD*0684=+(>:3A/E%$=65D(=*,'46)8''*':B>%<:3H4&(A+/AHHA(.GE#9(:A03/&>7-7;;1GH$<*A3)H?6H+A+>F;(#@&C7(%?5+8&4)#E,@2&2=,G/!7=6/<D,&AGC:6"@1>G!;B-2.3D8G5*0-.5!%)!3427!@-);$<>!E&"D+A&2C36;'"*72017G&,5,/B0;2@41D<)6&$EA!77H,>F)E,07*&C'13D&H1?61>7>A?/H=#(9A@+6/#'F-E@!@5A52<*4=4F&%!2A1E#/?.?/%@=$63G<>BG-C@+&1B:2>E+4?;%HB<C4:C-%<8='.HF-@7=!(5355B&A3)+:5&)?+8(#7%D!*GH4+C,&14>77G9G7'42H3@84H3?%1'F8@&!?!CCEA-:;6%5-147*&"5A*%?C')#H7:<5#.E#45-?;@0)'97;$))?:&,%12(>09&?$:E!A;B!:&&7+:)&088?$9)6(19@6C;22-7*EF0!@>'&+<@06C+)H)-/&$1,C
@r5766
ATTGCCCTGGNCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAGTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGGGGCAGCNCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGCATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGNCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGC
+
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
@r5767
GGTACTTTCCCAACTATGACCCGCGTATGAAGCGTGANGGCCTGCATTATGTCGTGACGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGN
+
:*$C2@HE'<"-:>+&!>-G@;0*@8*"=96D'BDE&@BHB,A'&2&+)BD'$64;;@9C+<C;%,7+A=:-8@A90<A1171@;!)B$$F%.,6/=
@r5768
TAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGTCGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGANTATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTNGCNCTTGATCGAATATTTCT
+
D541;$%-4/--*B!2!A8>*'%+A**2B&=G2E*GG-&H&7!525)=3%;H"'+C*(2AE?A9.B"7.CG3C%@/31H#%B5G7=);C"F3"@2--E=4A9H5F(96%&(=%A($(5*A+;D<'H&'4!?E91%B-#-G>1$!7#B('73?45:A>8?>2EB"::)><"</600.AF.8D0@/;;>(!>3H5=A,.D(9;%D83<E!5""+@09B&&E'*?'*%4(3&/E?*?=81?(89.9.H,=6+43@90<G))>BH/=#43AD0%F+).(=4DB9*2F8&-+ADH>1@2=C5=+A@4-7,4+))=3/!!$"H$
@r5769
TTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAANGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCCG
+
4#65(03H8EB*2=+//28+*B;@-.12?86?0)6%?;F,%!)H.3C354G?!@4<74/,<8<1'$A/GC4HH%H(8-%:*<";C>A97>21D8'AA@./$1853!87)45)G$B2"7:)<&)%>E:(:$8<%<:.!<(E=!?!>*@!@$%/4$F+/C.B)46G.(&?!&5,4"75-6..@4:<2H,;5:0@.H5<"78H#'H76E":%>:%5D+(F%=1AB@7*+/?-GB>+4$D&EE+&@
@r5770
GGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACNCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATTCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCA
+
)+)D@6+3.'?'5*1;"-B9+3*C73%$-5+#-39?,@)G2+8>G"C9F&8)=3$(?>=+4F?5%<#!1<%;2/25#+>00@H/46&@7/<F'%7,A(CA<?(,=85043?D.)%8.<(.+(.E1<71C@#8*5BHGEA;?G3,"C(#2+6.+"..%1*>-"/??,@H="/A89.0&+2H'&E+??ADB1%C*B<!""4&>8>&(?B'&?&=/,#,6@*A:>EGB>,1)9,2>*F2(;=B<90)"C#;EH32,>>"7@>-=F>F430,1B&4*7F),6*<$-@
@r5771
AGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCA
+
90@5:>GBG*FBB/6095<-G6H(@,CH$.&&7?1A!>)G?#2>8
@r5772
TCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGANCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATT
+
H4%7+"A:6&>E:BG=+"CH*H>",;C%$.;<5<.?*..B@&7D69!)A2?%>'>=32'0F5E'4.85D8>672!DFGDE*-:..0;3;'&9C.,(+;E(=.5%08(F6'--1;049D7H)A
@r5773
CTTNAANGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTAGCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTANAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACNATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCA
+
()%'%*!+)$+!$"'(&*)+"())&(%(&%$"###$+(#)+!$$%"(&("!#%&#+%&)#(&+$&%!+!%#&))#'#%&(**"#(#'")('&&(&!%#"*+%)##%#(%!*))#)"+*!++&#$*+!(&()#()!*$+&#%'$+)%#%)"%''!*!&('!'!&'$"'$*!'!+!)"!!(#'*)(($)"+)##)!+"&**%)")#""+)+$*"'#*#)%%!%'*'%))(%#*"('%"%##%)+))##(+"'#&('+(+*)')!(*&$%*')%!!$'%'&#)+(&%*+($##'#$%)!!+**+'+'&)!'(%)!"%'+(!*(#(+)%%())%')()"$'')"*$!!&#&++&!**(!"'**%!+(!(+&+&#!!%%#*&&++!+)#($*(()+$&""")!#%)+&%!&(
@r5774
GCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACG
+
9/@A-#-1F9#:+98(5;D9>6-:2*'C0#AB'$?.@8'D%5<.F2?.6'#B+H?3'&/1A"<"+G>!AF$CC*B5G
@r5775
CACAGCTNTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCGCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGCTATNTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAG
+
E**D'B&748A8/+-FE..;4D$6-25*3:+!A)'5-F445(&".H=-!!$:2;$HF'9%?H$D6);!H.0:2%$/+@'5*?ADGG5='3-E!A$9CF-.548(*B$.1>,$@#<<,%&E#H'7*',@"&:"E(G"9-6&B$,80G:C/G633755-&<46+--@#3),B12)G3)0&<7*F0,9?-=+<B+*@B+F'4:2"#:+$1,0#GG36AH!4E+%@F)*8H6!14/??0E;>AC"1>,E;C7F0?G=FG0#.?2"'2%&*%32C5+1</9)=.&*D*.%)31F;C%?>+.!&2/E#4@0H=&F39(?
@r5776
GCATATCGAAGTTTNCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGGCTTCCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCACACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGAGGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCNCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGNTGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCANGAC
+
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
@r5777
CTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCATAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTNTATNTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGGCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATACCGATGGCGATAGTGGGTATCANGTAGNCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAAC
+
&)$(+*++((''&!*!(#%!())'+!)#+(*)$+*")!+"+"(&!!*&(+&("$%'*'#$(&#$&"%'*"&$(%*#!%$#*(%&&)!$"$"()#"*)&$')$+'%*#+'!)"$"&&!(&$##++!&)"'#"+"!!(#%!!#"(&&(&#%*$%$!++$!"*)"(!##*%*$)(#$(%""+((#$'%'%&+!"'+#)(($*&*)&&('()$"$!'))#$#'%*!(!%!$%(!+"#$$+%)"**$#%#++'$)$+*$((#'##!%!###($")!#+')&+%(*#%'(&+"*!&"&+%!*$"+''($&)$&!!)%"**+$**(%*)&#"%"(++#$*$"##+)$($#($()*"%''#$++**$$"((')&'&)#$((*+!'##''"'+*$$!**)"&!)&(#'*$"+%!%*!)'#"&#*"+*+*$&%$($($')!"!&&)%)!$#)#&)($#%$!$'$)#
@r5778
TGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGNGCGTTTTCATACGCAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTT
+
2A&A*'.8G>9"'%/3FC;E(D8<:;@&868(50#%(6"2C1F&CC/974?9/2CE#;/G%<.#*G>$H>H?:C?$*174F/3:H,:6)9.7+6-;D72$%2+130D6A4<4%&*(,B3>A=08192+-A-:,8;+25?6(BG7+%::>1&(?A.9=+(7A@"$6:"-&2-+/'.8:B&5?H3#,2@F:*,''&B;D7;%)F&8A@),8;E$??>C%!<=&2:.@7(.=7B@7HF,7)+@,:/-B@/B80B@38&"%A,*#(@,51!*%1?7<(:'D,'**57C4#84/@AA780/66*"&GD+'.@0.+@%C3!.C<>B!-34%G4A*E!C/!?B)7"7):D!(<B78:#.$D&$2%H)9E
@r5779
GTTTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATNTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGGTCTCTTTCTCTGATGAAGGCCTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCT
+
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
@r5780
NNAACNNNACTNTAACATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAAGCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATNTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATACTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCNGGACGGTATCGCGAAAATGTATTCAGAAAATTATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCNATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACNGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGNAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAG
+
$!!!'%)%))'!!!*('+(%!+*&%&(!(%%$"!&+#+*(&'##!(&#+$#&*"%&*')(!"#!*'(!(&$#'*#$*$"&+#"#!'%"$+&!'#+"")''$&("*#)!'*!!**#&''%)!)$%'$()%)*()"(*&'!(())%&!'!$+$!"%*)($!)%"()(&!)&&%$$&!#$$'"'!((%#*'(!%$%"%*+%"''(#!$'"$(%%(!+#(#$)*"!&*##&((*#"$+*++'*&+$)#(&%&!"+)&+'(%)$#*'*+#+')!!'#'!!%((!(#)''+%!&#"+*#%%"%!'#"+&'!!!"'#*&'*")!*"&''!')#*%))$$$+!($*#)"$*)+#$&*&')"**"&)))*(&%"(%!'!%('''!+$*&)$%)&#&""*(")#"%''%!))*("'!*#$!'(#!&%#"!*#&#%&%(($&"%)$#)"')+*+%((!&#')#'&"+'#!+&'(")*%!*&&''+$&$$((%#!!#$&***#$&&*"#!')*)%)!('#%&'!+!()')'*"#)+%()&"+)##%%&*&&*%+&+)*)#%!)')"(&'#!'##("$!%+!"&+#'&'#!!!()'%*)'!)($&&$+!"'('+&(&%*'!*#+!)"$+#*$%""'+')%&)(%&&$&+%(#("#&%)("&('#&"+*&*"$+"'('*'#'($!()&&+'%%'%'$(%$++%#(!")+$"&"((!*+&&(#*%)'#+#'$+!+&$*%!(*%(""(%'%&$)(!)*('('%+!*$+(&"&*$'(#&)!%)!(*%
@r5781
ACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTCATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTNATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGANAAAATGAATAAAGAACNATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTANTTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCATTG
+
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
@r5782
AGACNCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTA
+
=&@+EF2'$<!)C6<$E4E5-#AG()#FA62B#2G!-H$GHH106?1C/
@r5783
GAAAGAATGGNCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTTGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGNTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCT
+
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
@r5784
GTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATCTCCTGCATNAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCNACAGAAAGGATTTCCAGCCCCCGTGCTCTTC
+
3B07FE(2%))"!G-:D:2/!4A98:2%97B;E2@5(!+56/G*-C001=4&$46H5'BF16A!F*D-?G:(7;>A4,58"4(0?B%>1CB4&>4G.(4"4"%39>;-3*/-@*!"C*3)';*$596)A5.1:22>-!D8H-FC+G009.>8BF3>@B(H)4'4<+<&B*B--;-9#*BA@C8?>="E5@H,B*&$.1@1G>'5&0D'(<E":CE#"7'5?>*33'01#>2#2?F90%H+7B4545.*4H54<#/H0''G$)4"D6,/0C!A
@r5785
GANNNTTAACNANAATTTGNTTNNAGNANNANNNCCGNTGTCCNNNAATGNANNCTGGCTGAANNANCNNNCGNNNTTTCNNTNTTNGNNCGTNANGNNTNNNNNATTANNNNGNNNCANCNNGANNNNNGANACNNNNNTTNNTNCNTNGNANTTNNGTGGNNCAGGACCNNTNNNNNNCNNNCAGTCNGNTCNNCATCNNNNGTNGTCTTNANNNTNCCCANCNANNTNTCNNANNNANNNTGNNNANCNTNGAGGNNNTNNNGTNANAGGGNGACNTNTGCCTNNNAGGNTATTNNAACNANANGNNNTNNNGNAGANCNT
+
#"#!#"#$"$!""#$#$#$"$!!!#!!"$"$""!$$""!#!$!"###""#!""!""!#!!!#$$!"$!"$"##"!"$$"##!$!"!!$$#"$$$$#$"$"#!!$"##!##"!#"""!"!!#!$!#!!#$"!"#"""!#!!$##!"$#"##$!$!#$"""##"$!#!#"#$##!!#!#"""$"!"!!""!$!!$$!$"#!"!"$!#!!"$#$"!$$"#!!$#$"#""!$""#""##!"!!$$#!###!!$$$"$#$"$""$!#""!!#"!""$$!!##!!##""$$!!!!!!"""$!!!!"$"!$!!"!!$!"!!$$"""#"$!"
@r5786
TTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCC
+
9/,75#*C:32!6><6@.62F2!C35+$$A*G2?7)$@3-A2<>H90A&3<$89"&/
@r5787
ATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGNCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAA
+
7G(<A"#@119=27.+>$%4@'(56:+,66A&<=4,4B3#6:CG'B96*+*BFDE?.ACG<76!4G*1'$#*)<*58!.&-.&?B?8)>1@.>5B7@$:D(7:'%4,:?6*2"H/.:A#7.$C,7)>C*#A8C/F$1&#%2!H+-1.:.H:4C,D
@r5788
NAGCTTTANCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCNGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAACTTTCCTGACGTAATGTTNATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTAAAGANACGTTTGGCTGATCGGCAAGGTGTTCNGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATGTTCATCGAATTAGGGGANTTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTCCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTNATAAANTCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGNTTCAGAAGANAAATCGCTCTAAAGCTTCAGTTGAAGATATTAANANCAGCCNCGCAGATGACGAATCATTGNGATTCCCGTCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTNTANTCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGTGCNAC
+
!"!##")%+"(!#)"$*!')*+'$+&+'!$$+%%!%))$)"("(+%"%(+&)+"+"$"#*$#"+*%"+)!&+%(!#$#)"''((#)#)#!$'&#++$)*!')&#)&'*!!!$"$#$("!"*)#'+()+$%")(%('&#%&"****+"+*$*+))*#%&#)%%+)+)$(('#&**$"+)**($)#)#%&"%"**!(+#'#'+**$)+*)%"+*'!*"!(%)%+)+$$%(%&$*+&''**#)(*(*))&!!+)&"($'!'+#)&#"(!%#&!)#(#+*(+)%%$*)+&'!*#(!$*(+"+!#%!#$'')*$+"#%)*#)#**%+')+!%%('&&!"+"("+*$!()%+*"%"#%*(%!%("(#%%!%&"#&("!$)&*%)!$'!&'%'(*)*"(#*&)&%*&)#"&#%!%"'*!+%'')%(%'$&&*$!#$('%((!!##!)#+"&!!++'&+'$'!)+'("!#%%"'"&'!+(+#"*)+!(!!'*#$&"*&'(&(*$*##(")(%#!&*%$*)#&'+!()(&!)!"(#%+"+#)'('#()*'($#*"'('$"'*+&+$!"("%%%&)#(*#*+*&#"#(((%%+"&"+*"&%%'%!#+$(*$##+$"$*$+()#"'%"%(+!)$)"%'#"#'&$(#&#)&'&%)%(%&%%#!+(+&+"&#*%'%))+$)!#*!(#((*%'++##$+#+*$)!!%))('%*%'+$$")&)&)"!!(*!)'#&!)$*)'"&))%##*$!"'$**+#"!*''%**#*+%"&)&'(&+(%!+"$'!)+"!(#!$$(#*#"$*&'*)%"&$)#'"*"&"#%')%&&)!*)'$*)"$&+'"$(+!&+'%!%!!+(#$$$)+*")++(!+")&&(!'&#!$$*%((*+
@r5789
CCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAATGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGNTCCCGGTACGCAGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGNCGATCAGCAGAGTGCTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTANTTNCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCNGCAAATCCGAAGGCCAGACGGGCACACTGAATCATAGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGGGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCC
+
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
@r5790
ANGGNCCANGTCTTATCCGACGNTCGGTCCTGCACGAACNTCAGCGTCTGCCCGTTCCATACCGG
+
$!(+%$!*+*#%"*'(*+"+)!"$"'!!&'!"'++"&#")(#!)+$#+&$(("&+%"+##*!(%&
@r5791
GGNGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGC
+
%()'*)'+%%#('%)#!)%''"!&(%(")%(+"&!'*$+"*&'*'!((")*#'%"+*"#!)"&&"*&*$&')$)#"$(+*#'$"!$*&!#)"&%&'(#%*&$*+)$)&*!$(*%*%#+%+'#*+!%##$"'($!)**'(%%&!!%&%'(#!'!'#%&+#(%!*'*!"'##("##*%%&$##''!(')#('($")&)%#+
@r5792
NAGGANTANAAAANGTTGTAAATGTTAAATTCTCAAGAAACACACATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTAGATAATTCANTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCAGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAT
+
#&*('!('*&+!+"(##!#%&'))!*'+$!!"*!#$)&%!'$(''($()%&#(%"&++()*"&&&%%!')&)##(*$'%+#!(*')"$!$+*+!+"*&)+!+!'*'+)")"+##$()*'!+*&&""#"+(()#))*+$%*'(+)+%)&!')$##&*(%$&+*!&!("****()'&%+""($&#!))(*%'+%&"!%*#)(%$!#+))&%!'&&$''%(+($&(!(!)$**)*+$("%*%"($+#$$+%'!&)()$)"#+"(#&"#(%'*%*#(%+%%%%"""%##+(&(%()+&'''')($'%$'%)$*+")"+!+'!"*!&(&#)$)$*%%
@r5793
NCANTCGCNTCCNAAANGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACACCACTCCGGTTAACGATGAAACCATGCAGGAGCTTAACAC
+
'*%!''*#!((&%('%'"**$+!&$$&#(*&""!!"&&(!)+)!)+!&!*$!!""&#'$!+'()+$"$%!!&%&++(("**%)$"!(%)+*$)$**&!''(+!&+"'#$&'!"(+%""&#"*("'&(#+#$)'+"&*$"'"$+)'")'*$&*((*#%!&"%)*(#$&*&#$(('"!(!$$(%'%''("#%()
@r5794
GGGTGGCTCCGGCGGTGAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGT
+
FD9"20#7).=,!7&?"0>)<D42"G4D!:F/F9767:*&7D/8D&4B.8<=HE1.<G',),7%>*7."0%8.(<$=E(.>*:#1$,7:@E8*"03,?@@BHA@*()B=0-&(:=!6?F74"27)=5(G&CFC5=3@D+@-=*-)/CFF<<*>4>*?<"'7F49'"G5A=@(C,2-B+4+E8
@r5795
NGGTANNAGCATTNNCGGCCNNNGTTGAACCGCTCTGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCGCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGANACAATACAGCACGACCGCTGACGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCNGCATCAGGACGCAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTNAGTTCAGTCAGGCTGGCGGGATCATTTTCCGCAAAATACGGTAATTTATTNTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGT
+
&!'$)%#'*&'!!&'")!)*##''+(%*!#*'#*+"(&(!$)&$*'!+$+$%+!*"#(%(+!'!(!)*'!"*'(%$%(+&"#(+'$%"&#&'$##"#&$'*!*(+!)*!(!%$"($)'$#+!+!+"+')#*(&"#)#&("))%!*(%"%+#''+$&!$)%*(+%$("#"%*$#&&'+$)*&$&%'*&$"(!#'&'$*'#+++$%""&!%$)*'%!(')&)&%&'*+($(&+#!!!+!*$*&*&#!"'%$+#"%%%%!&($*%"!()#%'""("&+"(*+'$++&)*%))!&()!'%"*+#(**$#(&(&)$'+!$&##$$(("#&%&""+)"#%("$$#*$%%+($)")('&(##"$*(((!$''$'*)&+")!%''")%)#*#%&!$!'%#$&)!$$''*%(!"")+#!'%+$)#*(++**(#!+*+&""#("(*')!+(()*)'!$+%"((+!##+#"#%%)(!%+%%(&)(&"!!%%)#%)%!)#*)+#$#"*!'#)#(%#(')!')#)+$*#%*+)"(*#(&#$&#*%'*)&*%)*'"!(+%&'%)#%*!($*''"'!&)%(("#$%%$&$#(("%##)"$'"*&'(+#")$(!#!!!'$&&!#)#)#+#')&")"&"$**(%&"(%$!''*#$&!"&%($"**)"$!"%*%$"'!')'*"#"'(!+#
@r5796
AATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTAGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATNTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGNTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAACCGAAACAGTTATGCAGGCTCTAANTATTACCTGCGAACNGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCNTCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTGAAATTNACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTGTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTANCAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCGTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCNGATAGTTNATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAGTTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAA
+
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
@r5797
CTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATCCCGCCAGCCT
+
@0*/7,-C0<94##9-=5".,!(%45>@&%4G1"',"D-3><@$(%8*E*G1(;%(
@r5798
CACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAANAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGNTTCATCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTC
+
/90H=0;!'*&GB*)HF$&H2%?48:8'2+5)%<622E)D;%?+*"+/4;>4?/9&!0C,&/!278>.-0F;1G"7F;7?(B@0*H82%6)!@;DCD;1*A0)?EF65$G6%;5!>7HFA$"&9?E?%=9C'3%7@:3+9E:,9:)&6G''0&1669B-H91C*F1();.6G)GC7>%26;'@!%+!1"4-/<'AF<BG&#=/@&AG%.C*,%6%'(G7-AE&:>/H=1)2(39(7,-A@>258,C!A!)1DACH:4&48@#"?-@+%!7-<%C<'=C1%@#*2'A4&3E,#,@0#2<1!!G;:@D7C34F$>1/""<ECB"=;*7!<&#1+)>#H3>)!"#+';(87H(G#H@-(F#F';5<'D#C-98)-+-7?A%?=BG&7!0(6!@?<.<8,%.!=A(=D@7E4CC$#D$72G50G<.6HA9
@r5799
TGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGT
+
H)./&GB6HD==!$%14'!C62-EBC?*A!6;/.@*:@H;0$>,<?"8$FA#8!<(3$F@8:!85A,?G'-:1>DB.=H/*8&;;2+
@r5800
GAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGNGATGTCTTTTTCCGTCNCCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTATCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGNAGCCGGAGG
+
;C9(AB*-+")?B"6>"1!H:FD*."3C//'>/>(982@GE?$?!?"C$/A6+=7$-;(..8F3/*B793',?#>D(G&.G>30%&+:75:;?B><,9'HFB;G9/2.%GF)7>%1H=-A96465&@$&#2HB%2A@;3@=7((:A?2D#)12*B?2?>"1E8$F1=E(9=82<&G**FF-%-8?>B0746-630C$5<<'F#>1&!34CBC$-A:F4*5)*F-9F"=?>$3/1;!.2,&"B(4%$(96F
@r5801
CCCNTAAGANNTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGATGTTCGGCCGATGAAATGCATANGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATT
+
#)"%'$(#&!&"&)++$'!&&%+!!($$)!(#!*'()+)'%(#'++*#*(")&!)$*%(!)%+%*"'!#($)'%))$)$(('+)$'+(&(++"$+%+(%*($$%$(%+%)+)#(*("%%+*))+*%*&)$##!$'"&#)'#!$!!'#!""%%$*&
@r5802
TGAGTCACCCAGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACAGGCGCTGCGGCGTAATACGCGGCAATTTCACC
+
,"3$9+-@)04G$0$F5-:$CA@A4D:%216+&*CF7A5F,;E@&#.017>@D#2/=!,%?CE9G?-AGD?@-&<7(#<7>
@r5803
TGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAAAAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTTACAGCGGACGACGGCAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGTCGGTAAATGCGTGGGGAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGACAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCANCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGNAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCTAGC
+
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
@r5804
ATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGNTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTNGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACANAAAATTAGNGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATGTTTCTGGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTNGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGGATAAAATACCTCTGTGCCGGATTAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATAT
+
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
@r5805
TTTTTTGCNNGTATTGCCGCCGCTTCTGCCGNACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCC
+
G8;+1?HC&'7)5+9HC5:1,(-E6&9@H"!-1)(4#4/"$*H'&/;2$(;+,"8?3H0)(4<"?BD!):1!>57&G6!'9?*255;!:46%"
@r5806
NGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGNCGCTGGTTATGGTCAGTTAGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGANGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATAAAAGCAGTCTGTCAGTCAGTGCGTGAAGCNACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACA
+
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
@r5807
TNTGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCGATACGTCGGCGGCGCGTTCTGCACT
+
$'G5%&%/39?,:'HC''4.C!0"4>;30:8>,C+;G4A4A!/%)B8"=1!G""G=G)$%8/GG41?7/!6'9:G7
@r5808
TAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTNCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGCAATGTCATTAAGCAGTGGAGAGCNCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATACGGAACAGAATC
+
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
@r5809
AGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTCAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCNGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGNTCCAAGCATTGTGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCNTAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGT
+
A9?7*,=0,,/</'@H7&35FE4F2@+9.+04C4$E&C3E>%G+76;>7%E>A>/?E#""#G%$.,59!E8?==&>63@5<G4*5!'83$.3G!>*?F,08>*H6F;+&524.E#C<58.72/''#1<!..<@C"$!F/+%)#4DD!1,#!'H:2BD/9$D96><54C)!6C>C/BG3:$G*/"F>82<:'C&FHH3"0+39=@8$/B*))3=,(7/66HA:<H,<:"@@A?>)$>H/+36+?-*9E8*D8+<2#(!(0&*'3F)=HC0(AC5D$"4D"'?1"/6.3&+>,'&%,/&,.+18$?49@"F6</F75EH)/#G+*F47:A%HD4%$>?H%/7"E*%;":9DDH(50F.%4<A1D:49ED?0A+78A@+01@$#AC:>E#2"F).C9H,G=/"+%/#$7-84,+H48A2>=G=,;F"ABD&>:;1E5!4DD.?=9,B&FF9%)0)2:H73H"2/F$.
@r5810
ANNNNCTCCACGGNTNGCAGNNTNATNNNNNAGNNGCACANNTTNGCTNNCGNNNNTNNCACCNCATNCGCGNANNNNNNNNNNNCNACCNGNTNNANANGATTNGNNTGNNTNNNTNNNCNGANTNATNNTNTNCNNCNANGNNNNNTNCNNNNANCNGNNTANTGNANNCGNNGNNGCNNNCNCNNNNNTNAANCANNNNGNNNANANNNNGNNGCNNGTAGTNNTTANNGNCGNCNANTNNGGCNNNNGTANNGNNANGNNCACGGNGATGTCNNCANNNGNNGGNNNNGNNCAGNNTGNTACTTCTNGNANNAAGCGNNNNNCCNATNTNNGNGGNCNCANANGNNANANTGACNNNATTCNNCGNGCTNATNTNNNNGNANTNCTTANCNCNNNGTCNNCNGTNNNTGNCCCNANGCTNGNTCTCNTNACTCNNNNCNGNNNTGCAGTNCNANGCANCCNGTN
+
$$!!$""#"$$!"!!"##$!$$#!##$!#!!##"#$#$#!"!$!$"#$##$$""!#$!"$""""$!#!###!""""!!"###"!"$#!###"!$"!#""#$$$##!#!!"!##"#!!!""!"!$!!$$"#!""!!###$"#!$!"!""#"#!!$$"#$$$!#$#!$"$$""$"$#$#$#$#!"!$"!$$!#!#$#"##!###$""$!!!"##"!$"$"!!##"!$$!$$$!#""$#!$!!$!!!!$#""!"$"$""#""$!#!!$$#!$#$$"#!$$!$$""$!$!"!$!#!##!!$$!!"#!#$###$!#"$$$$$$!#$$#"$"#"!#"#$###!!$$$!!"#$$$#!!$#"$$!"#!!""$$!$#$!$#"##"!$#"!$#$#!"""#"$!$!$!$$"#$#!$$!$"!"$#$$$#$!"!"#!"!"$$!#""""$"!""!!"$$"!!"#$$$#$!!$"#$""$"$""
@r5811
NTTACNTNNNCAANCATTTGGTTAGGAAAGCGGATGTTGCGGGTNGTTGTTCTGCGGGTTCTGTTCTTCGTTGAGATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGNTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGNGNCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGNAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCNCGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAANGAGCTGGGCTATGCGCTGCAGCATCAACTGANGATGGTAATAAAGCGATGAAACATACTGAACTCCNTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTNATGGTCGCCCCGCTGTTTNTGATGAGNCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACNGCGATACATGGCACGGAGCTG
+
"'&&(#%&""%'&""+'$&'*%%$%!&)(+)+)+#&)"$!"%+)')#&(*'&("$&*%$+""%"+%()%$"(%&"')#)%''*%)!!("%''#"'$#$!)&&'*(*"')!!()$+'"##!%&$$&")!$*%)"$(!&!%&*#%#"#*')*%'+%*&"+!(!+)""&(!+"#'##$%"(!''*"+!*)(&(($$'$$#'((&'&%("+!'+(+*&$()"&#+%%##&!!*'$%&+&"$"+%!+$'#+#$!'''(!"))#*)#(&"!!&)&&%')#"(%&%+*$*$)#("!#&$)'*&&!#)$"+)%%''$*%!+('$*"('$'##&"$#!%$!%)&)(%(+('$$"$""#!&$+!'"%#%&!(("%!)"!'##'$(**##%&"%'$#%")%!+#')%++)(+&##$)!%)!(+$)"####&'&!(&(*"#'&&(!++(&+$$+%&!#+&#&+(()#"&$+'$)$*%$)*"&#'&*$()*)"'#)'!)"(("+)%(+"%+)('*&*%'(%$+$"((&%&!!('!&&%''$)$#*$%$%#$$))"'!#(+)$$($#$*!#(##(+!')&&"+$#!!$%#'+)&")")+!)%$(%#'&#"+#($"+##&)"%)()()**((**!+("!"((*$%$%"$*)!(%#!(!'((*+$+'*(($)+&$$$+%!)!'*+'"'*())#"*$"+&%+))*'!'"#+*(&(&++$'*%&"'($&%&"('&%%%%#**+)(%&+%(*%+++#+$'(*&'*#'((**""'#+&)$(*&!+'$)*&($!)#$!*%"$+'$%#+%('"+"&)$&*%++&&")$"%&&(#'%#(&'%")"%)!+'($
@r5812
AGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGAC
+
6D-0D6?E#70A$')&F9/)=HGF#"B4:AC7!H@')A/.%'$2;,F#(=>34!0$=;'<C4H3F:66?0(":CC88G3::3E=2$5$:<B@HH02=@B@%#4=C:,/480->!7,&=4F9BA%F5('?$HFB8-8"&.A:=<HB.'8>&1.
@r5813
NCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTACCGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATA
+
''(;0(99&(E5G53">B27!G">3?F4F&'/@>A*:#;GE/%<7-(H$'">H0DD%#.7B!78""/1,)/'<#=G)06@,*-063606&2/#H0?B5'9$&>=,;#5!/#B&-:&82EH&3"F9*!:B+@+2"@G"*#)7/C:'8@
@r5814
TGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGNTAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCTGGCTAATGTCTGAAAATTGAGGTGNCGGGTTAAAAATAATATTGGCAACCTTTTTTATATCCCTCTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAANCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTNCACNGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGACTTATCTTCTGAGCCAGACTCTTGTCATTTGTTTTGGTAAA
+
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
@r5815
GGTACGCTGCAGGATAATGTCCGNTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGCGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTGATCCCATGTTTTATCCAGGGCGATCAGCAGAATGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAATATTTTCGACAATGCGCTNGGCTTCATCCTTGTAATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGGCGTAACATCCGTTTGGGATGCGACGGCTACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCCTCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTNAAAGTCCATGCCATCAAACTGCTGGTTTTCATNGATGATGCGGGACCAGCCATCAACGCCCACCACCNGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCNAGCCAGCNTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCNACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTNTTTCTNTTCACGGGCGAGCTGCTGGTAGTGACGNGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGNGTTAATGGCTGAACTCCTGAAATAGCTGNGAAAATATCGCCCGCGAAATGCTGGGCTGAT
+
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
@r5816
TGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCAATGCCGTAGCGCGGATGGGTCAGCATATCCCA
+
>C%E6:480G"$C0:8.@6A=..>23/4G%CD@H2#=""">1&'<-'C6(G'7<G*2?7B=!8D4,/7#*B?2<9HF3'@$59?%5-6"
@r5817
GAGCACACCATGCAATATGCCATTGCAGGNTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAACCACCCGTAAATTACGTGACGGATGGAAACGCCTNATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCNTATAAAAAATGGATATTAANACTGAAACTGAGATCAACCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTNAGCCATTAACGCTTATTACATTCAGAATCGTCTNGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGGAGAACTGGCAGACGACCTGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATNACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACANGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATG
+
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
@r5818
TTCCNGNANGGCTGNGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCANGACCGNGACGCCTGCCAGCACCTCNGTGGTGAAAGGGCAGAGCACCANGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCATTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAANATNCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCNGGAGAGTCAGCGATGTTCCTNAAAACCGAATCATTTGGTGACCGTCACGCTTTCTGAACTGTCAGC
+
(&'&))%*%%*)#"&&+))%%')*+(#($+#$(&$)&"*!#)*#&$!(")*'%#&#&)&%)$')!$()%($()$)*(&)!"$)$!%##($#*")*'!#!"&!)!**'*&"!)&$(($!""&'&'+*!%!$#!#")#""&*"'""*$&(*))&($#+)#$'&%"#&+(&"("!)+*%'"#+"()%$'!$"!'+&+)")&(&*()!$+&%*%))'*#$$)%+!$#+&+%$(%)%'*+$%%'*+!)'*)"#*#('!%!"&&*)&%*!#&)+%$)!&#(($+*)#)&*(*$'"()*&%"*$"(*#+#)&#)')'#&*()$+#'')!$#$+"((#$&!#&&)*')+)""$('#%'#'!"%&*'+)$#&$%#+#!#$%+%)#"&(+%$*!)%$!%%!!&+&)"*&%"$%&#''(""&#&$'""%*(*'&+)))"#*#%)'!&+)()"&*+&#''+!"*#"(!')"++%!!')'$%*))*+%"%
@r5819
CCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGNCGTGNAGA
+
65"A<=-$"4-#A#H87$:A>63>?CD8@3/BF##6)*BA4'B=>)";$21A>F>-0&&CC".C>#;.$%(+?;7'8F(-9D,;C7=<<*';":54+0;G38/<H!<7H0F),(H@)A8=1"*#/!!1'662.(%A:E&9(0,3&1$A235$/&0&7A'6HE'H"'%E=@;+0G%@28E?;%9+?6'(9#F.@>9H@*.AE5#=.
@r5820
GATTACGAAAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGA
+
0@1H3"!73?96D;,1G.-<*BB:/*H#9;E($AA'H%0.6@:.B)>85:
@r5821
AACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACANAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGC
+
92'-&77DA34#$=+?7&%$(>,3D5.'4G=->$)EE#.@#5?D"1B%+)H$?,(68!=/B)G4*D0A,";&-E":60/GC$@B,89A>=>7/$DH15E$#'(&),6)5.?G$?*%5735%34?6,&1034A:67;E0'&/"H.E<1@9FF?;0211F@C91,''9B$=>2/1A@0'<3=(E6,.>ED/0060?AG?;F*1B;E4G@&>30%!9';C=8()(5@,1(,2.5:*=F//-G;?AH/AG)D$@B:.2(?9*B05C,",&9)F7<>#,,0$/8>0FB8F+@D;.9A.5.,7G:!5B$DA0G0'?$9B)9849?G)%;
@r5822
GACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTAATGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCACTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAATGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATANTTTTTCAGGTCAGACCCGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGC
+
:6$9CAH1((FH:&:A:4.*1+!:&1:(*(16,>;A2G"A+"6&B+,'G>-,F6B?<7D=GE%3%2?57AB5'2-DC(GB)C6'@;D4D=+3D(3*--0+3A7DD83*1A&H1%@<D#?'F,'@,+$C8<-'D4()/9FG?#,<&#?;:)F2-B-G90?B"?A)F2<.<@8@),:A),$3:0=DF4:&,C7B>(#@E6#!$:('B;>>!2-&D(2D#25C97(B''?BC+<CH,D<#+<H2#,*A&#*C=97G!GF2A7*./0+#85#4$'61HB+@'GH=&@C3'"A9&>A=8EB*1*07@B,!46G3$(%,B;4:8+?4!;3?=,@8D)003B"*GB":!C*.=*.<2/06$1(C@+A/>1?1C<<+.3AG@#,",0BAA9>84*"-5BF@7646!GG1"#.!)F+
@r5823
GTCAGATCGGATGTGGTAGGCCNGAAAACAGTTCTGGCNAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCTAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTNAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTANGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTGCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTT
+
""B"A=#2?88*8!?%H<D,$,?!1&<*E7FA!/#5+<:FFG6#@F8@+'=7.7@D493.,1:!/DAG0.!9>7&:D1G,"&)4@<$:&+A)"&:&*.?:,7A"1B?%HF?9'A'(;2D$)+1"(&=8D=-1"7%E&)100(4:-CH:H%1%!:(>+*@FG.9&/?5@;>-..9D>5E(<,BD#A5/7.D<00*5G2*4?C1.3F%%26>E%&<?.4@:23E"'1E#=:"&"6:*4"(,(<B6),@?/74669<3.*/G2F@*,F3#7(E8%4C0<>$0/.C!45>ABD.CG='>!1D(.?A=?:((?')(7/)!!-!DE2"(8#C5C$C5,#&HA!0G<*H-1(%3C"3%9AG$C0)0795+26*<!H";?;!)E->#4C)<<>)B+8+?(8$&%F2)C3(E+AA)*/2=D-'<>(C+.9C/A5@
@r5824
TCTGCTTAAGCAGGTAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCNATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGNGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGANCCAGCGGGGATTGTTCACCGTGGTGAGT
+
&BF>HA&37)<H5<)G8=%6H,%HD!2H5(&)='&83-%?,>)28#3FFB3;CE/4/9%G*@!>#?)D"3:$8:%9@5A%CG/9B/2%03*9E3#'%-3/H(/AF39=*7@?F8<9E*!C0:"1+7"=50H)/H/A'9%;G!;,=4%=7==,4<*:/E<1.<*1&*>-(&4/28$,4,;-5B@H>@:9"+24H
@r5825
CGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAG
+
4=%80>*2%63#%GF!%$-H20:#/=!E<5C/;8HG!'"D/C$)-B$;9?G;@E6*=#'5D2>H;=%,H::6:>A3)F?H25F5#!9&)579&":%6!-76.:G?&E!$6%5!E(2&$<55,3H44,">+A+>0:=-;AA6F--+AHB"2&:G6FB,(:!.9/E:'587%E*,?E.F$/=)!
@r5826
GCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAACTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGNAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAANCATGACACCGGGGCACGTTATTTGATGGTCGCNCCGCTGTTTTTGANGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCANATCGAAGTTTTCCTGCCTGCTCAGGTGCCNGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTATCAGATTTGATCACCAGT
+
FF6G%,)"+&C:*,0(*;'-;!H1(F,1D+@#>BF)!/&!&+/H0H$.6'ED*+=)C;7*F;!<2#C&4H:@"4G408&/:5B8@1%0>@H5B4(4.%A.B"3:6+.E>HD6&3GB!86=0>,G0'><17(0B3;0&3A*4*@F.-9%21BH#(11'6$5H7.?7&0H/<#G,D,*2'552:3H*8=%7EH0-%=;0?!#<FDB+,70#?$?(E21:7:ECB,4909@,)6('HB,;@2)0H=+80<BD&0+18:*DBD0."4&D/H46;+B2,'<,6,G?<@*"(F&.;0@0+'6.C.!G+9(H7H-/E$3=F1'*$0A4;-7"4(B)61%7<,/BE$*1E+2/7G/E96EE9)G@+9938<4.9%E0H)()3F1GA97<EA?=&!"07(#=1!GBF?H?)=%:".AG>?0E
@r5827
CTGCTGCCGGTTTGTTTTGAACGGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTACCATTTTTTTCATGGTGTTATTNC
+
2-.-D$<B-D;$H@0.7!81"3%EE)H.)D;1!.!A6CAE%9C@DB,#5(@,C?'2/H"2F=+B<*-+G2(D:?&G;D.8!%0F&(+!!%=HCF-5!)">!&
@r5828
GTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTT
+
H?.=",/5C(2**<"!*#$4/!-07"?&#+5+D4@A&,,)5$06362<(3A-*7('BA=D&61A(1"F
@r5829
ACNATCNNTTCCCGATNAAAAAATCTGTCAGATCGGATGTGGTCGTCCCGAAAACAGTTCTGGCAAAACCAATGG
+
*($!)(!(#+%$&)+!')+'+''&$#'"("&$("($%*'**)$$'+""(#+"%'&*(%'&'*++")*%(!''#$+
@r5830
GAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGANTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGNGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCTCGGCCTGGCCAGAATNCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGAT
+
.G=C2#B0??HD<6(?">@=.*5<E:59G.C(A5B9:-+2."&E067>D1B(2A>81=&'-)!=)#0.31'8.;<C1$3#G'&!7%"6=;E,:3C<2CG/!-36H-D8@041<9#;1:2&:9!<+C%*"1:F&&&1%:+!-E&EB.1?8#!'$D$!/'3F1>A0*@-;$3/D*H!.7@H/H'";!G5(;-@E""+<!6G(#A2G)C8E4"?6/*A,B6)84,F)+6!-4)?'=!8G/179?;'&2)&?CC?G0>+5,@;?G3:*32CEBB8+68HA.&8@"#%'(''.3H32,9,0A4C(/4:*B&,!0;$#8@:?:&%7?B;>H@<%:$'H$8B5(AE4
@r5831
CATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTNCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCTCGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGA
+
B'DH6#3&0H7@H58=.,F/#2A,*+7:.3>'<(D9,/B$!/F>!?57-,&+-HD!!;C@;8%6=*7(/)386:-311=4#6.C0A79FC2*9G@3'0C2(473>C@E!<+E#8EE'G=H)B42%#!A/<+(,D$*&8=#H<34A3'"!,;-*4@5$F-+?97E&&0:$(5-!;G+9$D=#5HF8BB6.,+,':@'9(7&2+'B-&?F:,+/61!9E%)'BD<9EA?35<7F&+@<?9G9$C9%$>'2@A(!C8-<(69(?+A").H8#$2DG)4E2(,&1614G9!-,FHA=(8?9(7><-E/DE4'HAHG2!&-8:;-!C,&!HD,8);2'9,4+B367?4E26$01D*5(33H7*';H@.*@:-CF1?=/2DA5
@r5832
ATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATANCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCNATTGGCGTACTGACGGATTCATCGTTGGGGNCGGTTATAAATTCTGATTAGCCAGGT
+
0$DC34:77:G#@,H)30),@%(B8!D(9C=3*":?$%+,HBC#)*3(3=F@42>5*48%+@02*@EA,E-@55:%!7,$!/;%4E521)(@42-F.&?!DG/E>@#*D=AD+D'15-H&-;7#>>0)44!4/12B!&'DF;8:2<7)/3>1)D8@#B$@FF#=+35/H3FH%6@,1(%0>E#-,GD/"4
@r5833
CATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAGAAAGAAGAAGTAANCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGAAGATAACCTTCTTAAAGCTATTCAGG
+
14*4,,>'9/FC,")<71*B>B.89><!22,HC"40D@39D.4,#:D@H&%A7DF;+F'>"1!>4B!>F/-&$&'(!#7:.H9!&F?)+/"7/*;(@;4AF@*?3B"&=FF585+-.=H(GC)4&<@!6(CH3B8.;433("-8'!H4EA*-@<("B<BC(*!84D=#;G'E/-D;7C?H*0'&7'H3'1>F,
@r5834
NTCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGC
+
$F.-E0E(+H'#,!1&6#'-="&:47)CBB-4"--@F<)E7A@9<3A%C+!EA7$">%.5/#,G(@2G7F7.E(4>-6+B9))957*(&$!)0C.&'+"B=AH7*0@0
@r5835
GAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCNGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTCCGCAGATTATGTCGNTGATACTTCGTCGCTGTCTCGCCACAC
+
<1C1<64AD".E!)=,.-6+$0,#?2==3/"G59.GF9H1H+3A(;?FF$#="=+.#9E5--/D<%%G2:H3*87':@2E6*37C0:&65BF!9).'.5&;5$>H;E%>!AE+&108.1#/=GE?!?-=!FBB6<93>54.-7<=>2E:G9>B4<@F3!,??B3>:.4AH=#6<#25='$;/,&;!9%):?9A1E%D%8>8<6&?>''*H$:(8*<F48.3*9%!+G-=.64<,-*HD@@$8G@.&C,"-07F<!:&5=BG$,A=#C':7*$$'@9+!=2<1,%):.;D#/8):>C?F*'%0:+?A9/5)+E49.)."'C9,(>4>-5??D0+H;7>/473H-@3E,9BD0E$'A;)$&6,<)56G5-0":!0%2!?&)("34""78,FD)?:&E;F2
@r5836
GCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAAATCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCNCCAACAANATGCCGGNACAGTACGACGAAAAGGCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTNTTCGGGAAAACGNGATCACCACGATGGAAGAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGCTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGNGNAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCNGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCA
+
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
@r5837
TGCNNNGNNCANTNTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGA
+
'*(("!(#!)&$&&+$*"$%+**)")'!!*)++$$('+!'!'!#%(&$*%+$!$%)%*)!$"!!$+""(**!#"!(''&"*(!)+"++*#%#!#"((&'"!$$)%)!!'(&)(*%')$'$*&&#(#
@r5838
AGAAAGAGCTGGGCTCTGCGCTGCAGCATNANCTGAGGATGGTAATAAAGCGATGAAACATACTGNACTCCNTGCAGNCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCNCNCCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACATGGCACGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGTGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCNATATCCCGGCACTGTCAGATTTGATCACCNGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGGCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCNGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGNTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACNGCTGAGTCCTATGACGACAGCTAACTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGTTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGA
+
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
@r5839
TCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGANGCGGCAATACAGCGGTATCTGGGAAGGATCGTTTAAACCGGCATACAGCAACAACATGNCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACNGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGNCGTGNGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTA
+
./'"5#>>5(@=#5$;HAAE6::4E"?-ED&;H"-F8018<5!&&H9'C(H8>'E)&8874C!A'"/9/&:B$A$".E8>"*D7F6E>><D>2)9)831;($/C<EDH4!*$@A(4@=7;5:.=,6*;**4E07&=(G=<'F?B1:5$+99!G'+)'!GAG."$?,(2>:"-*HG:*<6CFD;2;13%'?A(%&:9=;;3F@41)E'=BH.;E%<+C&2A9<?C5!2&+66'.42&6"&7$H@5'#3(H"8>@=0;7.3?>;<+G8GHA7$G,0-,8A3(4$#$526C=<?)-E=C7-9FH$:%&80818>#4.3A(0>'G&<=17EFE>-!*+G'D666-0#@C1&9<6)5?):<<?G9<+")#=!@('*@C=+H$91*<7)#G>%,!&@G4=CH#&@*'1$3<<B!4A0CG#7C)(*;&,&//<8"<@2.-8E$%75",<@BGG5C-(8&"6
@r5840
GTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATNC
+
C0BC7%2D&G-DFH")&7%523FF3B>.G64A4F%,?9-7B@?C"/32@9E=B3"0"/G@,,A'7B$%F0=!9;E4-5>:?BF/5?8;E%A";=)$;?/;C0;>.":*7&B5;-A
@r5841
ATGTAATCNACGNAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTNAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGCCTGCTGAACCGGCGCGAGGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACNGAGGATGACGTAATGCTGATGACGGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGT
+
")$*&''*"'*&$*+)*&*##$!(&*))+%"*"!+(+)#$$'&((*+$$%)+""'!(%)*"!!""#%%*($)"(*)'&)&)"**$$&)!*%$$()"$*)($"#)'&!($)#%$+%$)+%%("(!)+$'&"&()!#%%#"(!!$'!)#*+#*(*'"*$'%!!%%"$*("*++'$+$*(&)%%'$*)#)!!&!"&"'!+)&'#$)"'$&'*)$)"$)#))+#'*%"%$")+$)"(*#%")"$#$+%$*(('$*&)&!#&!%&)(+*#$#!&'!%%!#**&#)$'#)&)'!(#(#'$&&*&&$!')(#(!#)&!)#&'(!*$'$*'&'&%&+)+"$"++%(+(#%**'%!+")#*)"%%*#%$&"+
@r5842
CANTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCNTTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGNGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAG
+
76;;AA"5:;59<.,3-F/)@57G4:9D19)4;72/9H72;2C:4G&-#6>*!$C/;D0>GE<(G@C'&GB>9=.5,9/<A4F4%E<D-B71(B-0H.=?-G&6609A.@<;@";*HE*<20<2.H"/7B=1<#&AH:G1!$,75%&6"B$4(-E$#4&&A+:5;D$&B/D
@r5843
GTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCT
+
4F@!70&3&E$+=*H0<:*4HF)(1'@-1&+(#90<!4.=C,.E5)G&8(5G+.A0>D@80@'.H0)0:=G(C>!E!!<$!#$7*4)@&):8:'*69H3+$!=9
@r5844
TCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCC
+
9;9@E0BG;2*0$!A.:2*C8"4%A)/+G(F%F(4AD?'D&/:<=
@r5845
GCGTTNNCNCAGTNTAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACNTCCTTGTGTTTTGTTGATGNTTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGNAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGATGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATACTAATATGAAGGNTNATTCCCTGGTGGTTGACTGATCANCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGANCCAACACGCAGTCTGTCACTGTNAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGNAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTA
+
"!&")!%#&"#*'+)+'*!!)%((%&()(&&($*&)(+("("#'$))'($(*$+!('&*&&)()(*#!)*"!!&"!+(#%$%$&#(')&&&'!$)'#!#+)"!'%'*!'!*'$&%")!*"!$+!$#+(%*#"(!$%+&%(+!($$#(+*)$!+")')*$"'"'"+&'#'())"+'#)!#(+#''""(!%#"#!+&%%#(+!++#'+'"*%(#$$*&!!"((&)&"!+!)'&+!'(""&'#"'!$$'(&#$!*+!$(*+'*%'$"%&!")'*+#%'%*'!#%"#"'#**'+++((!"*)'%!)"#*+*#((&$%#!+*#(#$#&&*!'*$+!+%!$'$"$&)&*+"+&&(&)'#''#$)(!&+(*$&'#!+&*!)!+(*'*%*'+&+''&#%$"*($)!!&#*!'(!(#'$$!&++#'!%$)"(#%*'#&$&(#'++#*!$)""(#*$"')$'*((!"#)%%%%(*'+)(!%"&!%*('+$##!#"!"&'"("'("!%)+&(*&+#*''%"*!++('#"+%)%%(()#(&+)'$+"#%!+*$$%*'+"%(&'&&'*&'**'""'+*+%#*$"()&!(*#"(')&%(&#'#!!")#*!(!+(+%)&)%#%")"&**%'%"%$$*+&$*$$'*$''##+)+'*#(*$*)%++&!)&&+%(!(+'))"*%%#)*"!+)("&*(%)'#!$'!**"%)*"*%+%*)*#!'(!")&(%*'%&(#%!$$$$((%+'*)+(*#!#$"!#*)$(*)#*$($*(+#&*$"$!!!$$)#'+
@r5846
NAAANGNTCAGTNGTGGTAGATTNTCCATACTGACTCCAGCCAGA
+
#'#'$!"!*!**%!%!#&#)"'%!#+$#()!!"((+##+#$'%*%
@r5847
AGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGNTGAAAAAGAAACANCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGGTTACGATAACGTAAGGAATTATTACTATGTAAANACCAGGCATGATTCTGTTCCGCATAATNACTNCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCNTTCTTGCGTAGCAATATGACATCTCTTCAGCTATCTCAGCNTTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTC
+
+)"!'*)+'&$+%('!&**#&)#*()+*$"!&((&'#(&*!+*))+"%"()!$+"$%(!+)!'')&!"+)%((!$#"")+$(+!)(&*(*(*'&("&($!*'%'*$$&%'&'%##*%*'!%'"!)+)'"***(*'#%'*%$##$#))%%#$)((+(*#&(!'%!&#$!&*)*#')(&*#'$*(")!&')!+'!&*"#"&%)"!##"(*($'"%#(#('*))'+++*'!*##")&#'&)*$#&%)$(!%&'#)(&&+()&''&*+#(&%+!'&*#%)%++)%"$%'!(+#%*(#'*!&**%*#$$!#$$""%%%&'%%()#)'!"($#($"'+*%'**&'*(&%(')#*)'%#+')"&%)
@r5848
AAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGACGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAACTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGNGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGNCGATCAGCAGAGTGTGAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAANCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTG
+
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
@r5849
TTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAGTTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCATGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATA
+
CC!2)C*('<F:#>"/E'9-F,@,&ECA?)#)A#D.3;A8'79*1'2;')#3<"17+7@7FH3!C<H>-&A;16(D9@4:>#+&D5$#@4%AD>;8:***?<3B:F!B:7"<(<48;#=1D54!9&E$%9D9(4FAH91!/16(3%$E2!?)5%F-&E6+';<<8'B<!D638;G>&+;
@r5850
TTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCNTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAAC
+
F2;;)0#'F&#@9//9D.D?<A'#$@)%7.D2E;$9D52+@9=-#.644D3'2+;@H>A@C1$$?G?>29/FA37CC<E/5#,4(<F=@#/7=)$@$E9+'!'.'),.!%;?";,/@G%A0167/G1&!H))=';#E;'"E-62EG4)"=&F:>>2F:7#BC'&&#8FB'8D1>>AA.E@6C&7><=?;H9*?E=H9+"B1;A6BE-$@&GC-2/(EF8,6$/0#,C.#0C<5C5,C3+
@r5851
AATCGGCATTCGTGGAGGCCGTCGGCCGGGCGAGCGATGATGCGGAAGGTTACCTGGATGTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAG
+
-#'&3GG"(5A"E*GA&(.)C.FG4,18,6:"C%-?=4#;(C2)&F,?891.?(")B"E8.>7,%'&4(&!.(.G><E"33#A2'/>-8?0;83><%,,C(-9<A>'=%%/D':3CH)93$E'F.@.;@'G%752#9"=
@r5852
NNGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTAGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGTGNACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCNGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAANCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATTGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGT
+
)")(;;4?,<.;/E0<AF5+,E=$0%?$A72!&CD(+!A;"5*&A>D$E<614<F/.>G*:%5/6$*>)'"#;+3:5B!1A$(<F#3G-7G%0#)C3A;H-2/7F@!C&2G':!=#'HB&*<66F>,68%>-$E?%!/2CC"99:;D-4@65E01-0G:F,D&@;0-B#H>8?4!66"%E<;-'(C$F==54C%6@B?).=8=?#?>F07D4$+'F.05=#GA#5'%2<=/2A(=43=@E-=B#(.2GF%/G?>*!7/H>$9/+%<@)';89A0+:D/+.E2B@"'1/1B-AE=0H0>&+!"%'H3,D*(1#+$*<&H"0@9)H,A1>*+&@1B+?-..E<=5$>9*A>BH8:?/6.@!'.G420E8@3)/#"@.9*;4'*#%?,G6:HFH/;:''+/GH180'AAC4.=/+107</'=D.&**E,,E7=::=:?3&<(G05@F,"0C"7'H%85.B
@r5853
GAGTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGNCGAACAGGGGGATGANGCGTGGCACAAATTACGGCTCGGCGTCATCACCACTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCNGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTNAAGCACTGG
+
7CH.(!@717BHFF/A=00D9"E76G?"4.!*'1F1C=)1+4>'E+$+'<7HAFD6.FE4,7>A3#*0)#F+A!HG%;-&:29***$(C"=A?3*&1$9EB7<?+3AE5&6"H'F(7?>F<8DG8:<D:<.B,#6(%*'?$$-'.D1AH%93+2B3<$1)+'+55H%#*)454'04(BH3&D0%!F&+D7(C(212G(?9!&7&6%E%+%!6B2C<?7?,+@&DC?G$2G5C2B1.;?4,%6+."$5?7&%8%+0'3!@"B=;:038F)>%7'/D
@r5854
TATGCATCGATCATTTGNAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTNTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTNACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCANGGATTCTGTCGACCCACAGGAACTGATCANCACTCTTCGCCAGACAGCATTTAAAGGTGATG
+
?(/6%<F>@"$=<F(8?@E/9"*?(3G@745E=--(/,4<-;1C/30+3H;77!;@3;:0+.F65&1<)2+8<G8#%2%7;=)($B0126@<!%G"=>4-5+>%"G1)&=%$F"5B!"G#),&&/8-,-<CF&-7*;#?3!C(0$<G;+.,%(;1-1;&9F#*=)G71%,,G;/93A.2!9B?HFA%1/78>5H?DE>F>2.2+.(44&8;B"B0E:>D/;C9;+..=(85'1EG/.*:=071#314=75.*?2/?)'&5!'D&BG?28$$E'*;1(@
@r5855
GTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAANAAAGAACAATCTGCTGATGATNCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGT
+
.8:D5!?*F*;/E<@,+8E6!(+%'?&!,?!;H?5/1@'3(*D),"?:9+&;B./&/G8'-$D5''BA6$&E"-E4<5/'/%/A56@5$)64/5@1)@?#G1/)"-A?#1"%E3'3#/G3>"?8++%2).*:?/456-7:H>>7""6;=8&?.:((015882'8+1<7:5007;9:%HE=.67<3@G7%)&!*D+46:+0+2?<4:G->"@+GA;%>02'@5/>@2>1/BD'!?/B$1E>+6@:6,-B+<5CE&5.4?8)8/=A.1"=;8,G>C,>E6,C5,!67"#-+<"7'1433$844'+-819EE=<#.7,)0DA(-E-0)).F0-3!,2'(D&A5>4;:0'E98%64GA<'G96#EC2D3##6+<A44@F(7?9*3442!9A1@)HA@8#.=9573$*:@3>7!@,=*&;,.E*)G2<64;,<-D"/5E<>B=7H$;,BH"9>G63B7AGA3.88DHH73H>6/4.*@C
@r5856
TATNTTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCANTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGANGGGCCTTTTCACGATCATCCCAGTANCGCGCCCGCGCTTCATCGTTAACAANATAATCATCCTTGCGCAGATTNCAGATGTCGTCNGCTTTCTTATACGCAGCCTCTGCNTTAATCAGCATCTCCTGCGCGGTATCAGGACNACCAATATCCAGCACCGCATCCCACATGGCTTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCNCCGGATTCATCGC
+
*:'8>*.FC,B%(DF(F;H=%/;A)F%(46H%HB(41?B%8H&!-?.<(6.E&$3@+5A0G=6@;C=>FDF/:2"!B4""1=':1EE'C3+6B=27;6F>-0HGC)%8C2/0*87&!()+:1=),/)9B72>43G/AE<@EG$.'>)9$/34:'%G%6+5D?@@2+3.9)22A2,6*#*G;#!?*,+:;50-/-;D#D!4&9H.=:=A)8*!B.A-D*(!#1E7+H)F:1!D6;'9<5<8$C2:;8B&$;7:+A:9/'?<(7;"C?:#58/A#*?4&DCG1&0*;07H*'B?0';,&>'EF.B/B<'9"G$?-(H.)D,'C$-<00E2@:C,%1(?65B<F9(D.8H,*"'%CH0?%=H8!32%7B>/<68#G;):!&6BAB064='"9@;/C,5G0G&##)-2<
@r5857
GGNCTANCNCTNAGNCGNCAGCCNNNNGGNTNNNGTTATNGCNNNCGGTNCGAANNCNNNTGNNTGTTNTNNNGTNNNNNNNAGCGTNGTNAGTNGNNGTTNCGNNNNCNANTNNNTCTCCCNNANNCNNNCNTNTNANCNTTNANTAANNNAGCCTGGNGAGGAGCAACGGNNNNATNNANNNNNTNNTNNNAATGTAGGNNGTNNNNGGTNNANANAANCGGNNNANNCCGNNCCNNNNTNNNTNCNTCNCCGTNCTANNACCGNTNNNTTNNTGTNNCGCGNNNGATNNGNGNANGTNANNNTCGATTTTNNGTTNNNNNNCNTANCNTGCTGCCCANNNGTCNGNCNAANTNGGCTCNNNNTNNTNNANANNNCGCNNNACTGNNNANATNTAANNGCNNNNTCAGNTNNATNGNACGNCNCANTCNCGNCAANNNTTCANNTGNNNCNNNGNANCNACNNNNNGCAACCANTNCGNTGANGATANGTNNTNCGGNTANCNNNATNNATNCNNAACGNNNNCANTTNNNNGTGNTNNCNNNNNNGNTNTNTCNNNCNGNTNCNNNGGNAGNTNGNCTNCCC
+
!"!"#!""$$$$#"#$"!"#"$#"!##$#!!#"#$!$"#"#"$$"""$$"$"!!#$$""!"!!#"$#"""!"!"!!#!"!!#!#!"$"""#""""!"!#$!$#$$!#!"!""#!$""##$##"#"!!$!!""!"!#""##"!"!!!!$$!#"#""$!#!!$"$$!$$$!$$!"#"""$!!"!#""#$##!##""#$!$!$!$$$#$!##$$!#!""$#"$"$$$"!$##$"!""!#$"#""$!$$#"$$!#"#""!$"$$#"!##!##"!""!"!!"##!#"#$!!!$$###!#$!#!$$!"""#"#""#$$#!""#"$!!"!"#!$#$"!$$"$"$#!$!"##!$$!!$!!#"!"$$"$$!#"$"#!""$!$$!"!!!$"#$$$!"#!$$$!$#!!#!!$$!!$!#$#$"$#"$$$#"#"#$#"$"$#$!##"##!#"!!"$$!#"!!!"###!$!$!$""!"#$""#""###"!$!$#$"$"""$"$"#$"!$!"###$$""#!#"##!$#"$#!""!$#!!$$##$"!$"#"$!"$#!"!!$!!#!!$"""#"#!!"##""$##!$$!"!#$"!!"$#""$#
@r5858
CACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAANGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCNGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTNCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCNACTTTGGCGGCTTCCTTTCCATTAACAAACTTTNGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATNTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTNAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGACTGGCTGCAGGCTGAAATGNAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCCGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCNCTGTGTGCCGCA
+
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
@r5859
TTNCCGCAGAACACTGCGCCGGTATCGATATANATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGGAACGTGT
+
)+)%+)"$%($"(%$'#*)&!!!"#'$$!"#*'%$!($'"$$'&*#'+"%+'!&&&&+*&%!%)+%(&&*!$$$+%'##'*#%*%%!$$
@r5860
AGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAANCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATNA
+
E'E!.%ECB5-!F:<DC*.(&20&*$@63569HE4'FA7F8.!+'F>2#0;*@<@(.6D:B$@+23.5AC;#5A##)D?=!D+:BDCG$8&BB043CG2E$*4D75#6.>-D4((-4+')'+EA?H@&%A5ED5*:4<E$5&%C*4=<*3%B%'@7HE:>C8F'>8.*=#55E1
@r5861
CNCTNTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGANAAAGTCTATCTCTCACAAA
+
(#'(+"'&)$&)!*(*'$#(&"&#&*!&$(+*&++)++$!&%$)*$$*$%)++)*%**#&**#!)%"!)
@r5862
GCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGNGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCNCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCAC
+
5&FAEGFGDE>.0)21=4$H3>,6:EG(A96D%$H?=#E":+CGD&9,86DC89G23'EG-@*%!H&@"/*<A/6'<E,$7A5?@A.<C:+$F3(9(>F384A"#/...D#$<%%';H6>D%EG.;:63D(C"94>;$0;?274);:B>55-A;CCDE75DCFG0.F;.->','=1<D=20D"#CDD5@H9(%='14"4>FA)'4/+,*+05
@r5863
GTCTGCCTGATGNTCCACTTGAAGACATCACCACAAAAGAAATTCCGGCAATGCTCAATGGANACATAGACGAGNGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGANCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAANACCTGAAAATTTATCAAGCA
+
DB8"7.$=G'>?&1G687#6((.1>4;/51!9H%5D@E/E6"$/6<<+0061(?*'74"!:/;BBF8(!?##.'#/%$(=4C1'0D4*=4BC1B&E+=6-&:9C4716*,'@93&,)+38'B<.86'C'9@#A-C3H:4/:'!G:,C"CD,/;646&!.',2A)9)'&H"%12<G!2=89%%=84$502$G,+84&+9)*G%H:.BCHAEEH$;*$*#!35#$8=G+(+F0%9)C>-.;8((G*D
@r5864
CGTGCGGAAGGTGGACNTGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGTATATTGCCGTCGTTGTCGGGCCGGGNTACCGGTGTGAGTCATCTGAAAGGGATTAACGTNAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTNTGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTNACAAATCAGTAAGCAGGTCAGTGCCTTNGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACANTGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGANAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTANTCCGGCAGCGTCCGTCGTTGTTGATATTGNTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTNACGGATTCANCGTTGGGGTCGGTTATAAATTCTGATTANCCAGGTTACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACNTAACAGCACCACGGTGGTGGTGAAAACGGTGGGCTCANAGAATCCGGATGAA
+
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
@r5865
AAGGACTTAAAAAGGTTGTAAATGTTAAANTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACNAATATCCATGAACATAAAAGATATTACTATACNTTTGATAATTCATTACTATTTACAGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGNACGCGCTAAACCCTGTGTGCATCGTTTGAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAANATTAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTNTGCGAACTTCAAAAAGCATCGGGAATAACACC
+
%)+(!$&*)(&*#$*')++)$$")')!("(!(!&*#&$#")$'$*+*)+%"")""##)((()##($#(*&*!"+*('%*'$+')'"!$*#*&'$))(+$'()&"*!&**!(*)("&#')'&!&!''"("#'&))#*+*"$!!%)!'#"&')$*()&)$(!+!"%$!($&$($'*#&*"$!*(*'&$')##*$+"%"''+#&$($+++*!'+'&%'$*#%'")")(%*'$&#'*+%'#"'+"&'+%#))+*'!)"&"*%(&#(&$%)'!!!+#'!$$#&$("$)'$&&)$$'"'$"#(+%$)*$&$(!'!*!)&'&$&''(*'*"$+*#&+&%!*'"+%"(++!&)*%**(#++$#*!%*$")&)!+%'$$!*$&*))$($)$''#""+(&(#+$"!#&*&#+'!!*$#))"!($#%)&&&()*!*"%)'"(*!%(#'$#*(%()%!))&"$$''#!#*%*%*)$#(*'%((#$+#)($#$!#))'"%)(+!&*)+&%$"'%*!%#+!(&"!'(*)+)''"!"!+"*&*%#$
@r5866
TATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCNGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTGACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCCGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGNTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGNATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGT
+
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
@r5867
CNCGTCACCCACATGCTGTACTGCACCTGGGCCATGTGAGCNGANTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTANACGGGCATTTCAGTTCAAGGCCGTTGCCGTCANTGC
+
*$#</-9?>D#*6=#9BD<:<C@*G7*$?G;?@$#>H0<9F#)-;'1-$%)D=B245GE2--:2#GA6.6F166@C(*+)((-50GCH'$F),#B?'(:3H&7?*G58:;A178+)B978+C*4F,BDF,+4G
@r5868
CGTTCAGCCANCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTT
+
:?"H@@>6>:(G:*002.:@B$?&7//E5$'.$06D)$$$7%/)39D%B3$
@r5869
GTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCTGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCNTGTTAAACGNCGTCTTTAAGGAATGATGAACATGAAAAGNAAANTCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCCCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAGGGCGGCGACCTCGCGGGTTTTCGCTATTTNTGAAAAGTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCGTAACTTAATGTTTTTATTTAAAATACCCTCTGAAANGAAAGTAAANGACAGGTGCTNAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTNGCTGACATTTT
+
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
@r5870
CATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTA
+
5&.."6976.+'>5?80-G(!803D3>/'G/"8:(,D2;18%A*
@r5871
GGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTAGCAGTAAAAGCTCTTGGAGTCCTGAAACAGAAAGCCGCCGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTAC
+
(C#,3/*G='9/046B'CE2D&6+6B''6@)*F&72D=<B)#$"3#90,::EF'9!F#+*D88!=&7982)D$$5;.A#+.7!318?H45'?%$E1&!?A"6G"%<C6?"**@F-9:78!FF'#D>E0280:%=@8$G9%-/7"@4-5B/$/+8,28&31CF6/9'"G#F6/%/DB
@r5872
ACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGANGCTNCCGGATTAATCTGTATACCTGCACTCCACGCCANTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTNCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTAGCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCNCACACTGTCCGTCAGCTCATAACGGTACTTCACGNTAATCCCTTTCAGATGACTCACACCGGTATCCCNGCCNGACAACGACGGCAATGTACCGGTTTCACTTGAAAATAGCCCTCCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGNAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATATACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACNCCCGTTCCNGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACGTCGATGGNAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGNTCACGTTTCCCCGACCCGCTGGCATGTCAANAATACGGGAGAACACCTGTACNGCCTCGTTCGCCGNGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAANGTCAGCGGAAGCAC
+
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
@r5873
TGATTCCTCTGCTGGCCAGGATTTTTTCGTATCGATCAAGCCATGAATGTACCGTAACGGAATTATCACTGTTGATTCTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCAGGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGTAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTANGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTC
+
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
@r5874
CGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAAACCGGCTGGTTGCCTCATTCGTGGAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCCTCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTNGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACANGACGTTATTCAGCGTCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTG
+
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
@r5875
ATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTAGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGCTATGCGANGCTGGACAATCAAGGGGAAACCCGCCAG
+
'!+"(()'!$)*)**$&)("$$'#)!'%$%$)!&%"+))"'#&$*+'&&"+&$#!)))+%()$!"""!$&"!)"!%)()+*+!$+$&$*)%+"'!)#!''$)$+%((*'&#!!#(+&+!)*!"&*$!#((*%%**&#"'++#&(&($$%)$)%+###%)&%!'!+"$%))%%%+'$%$$$(+&#'(!((*"'+#!&"*
@r5876
CGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGGAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCG
+
0>4;D3@"/,:;"#!G0B???+6(C)+0>?,=*HBE#7D;D!?"!+05EB=-/'-!<%!>F;-B/948E<+?!D"D&5)$D9##!"#='42<6"?0C/;@!9>7@#0
@r5877
TGCCGGGAATGGTTTCACCCTGCATTCGCTAATCANTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGANCGCGAAAAAGCGGAAAAAGCAGCGGAGAAGAAACGACGACGAGAGGAGCAGAAACNGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAANCCGTAAACGCCTTCATCAGNGAAAGAGA
+
&+"*$()'!(*)!+$")#)"'(&&'!($&'$+"!*!($+*'(!#")*)'&!"()&(%+**#%(&&*$+%+%*!'$%!$#")%&!#"&+*#%$(+%"'%$")$#"*(#!(+%%)'%*&)#!#!""&(%''%&+"$!%(*&%()+&#$!%#$&))"%#'!&(%((+'&#!&*+))&$!")(+$"**(")+&)%%#*&!("%)*%)%%"'**'$(!&+$#&&'(+&+(!#'&"#%$!"&%)!%#+*"!!!%
@r5878
GTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTT
+
H7&8."=AG@415(8D>>":H!@'8$<'8776-++<!)":;#1+A>!G8;!6"7+=3/.8<22-8--2(EB<*/%3*844B&E/>E;",,.<:5/%0
@r5879
GGGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTGGTGATGACGCCGAGCCGTAATTTGTGNCNCGCATCANCCCCCTGTTCGGCAGCTCTCACATCGNTCCCGGTACGCTGCAGGATAATATCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATG
+
*+!)(!(&"(#&%)"("+*%(""&%(())+'#)*%($%*+!'%#"!)"(&&(&#!#$($'))!%''#$!*%'%+)*#!&*$&$#(%&!+&'!!+!%+!*&$!!%$($!'$""#')&&(%+#")!!#$$"'"&!&%!($!)!!(('%)('&*+%&!"'&!'#&($)()*('"(")&$%!''!*'&"')&*)('*)+%)*&%#!%$($(+$&)&#!!!$+##'(!%%##$+*)%!&#%+!&#*&'#*)"$"+*+&$"$!"*()&($%#$#!+*)"&((+(!!%+(#+)"!')
@r5880
CCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGCCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGACGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTT
+
HD6@.-<=+"77H5$8B7A('F/4516+"B>,'(4/B@)'#8)#<?/78#?6'%C"(-!:'<83&.?E;+C,5E2))$*+9*'F0"1EC0->F>>DH5%H4,$2#?1&%#!+C>"!&;,:.?&2)B<?=8-=C$=<E3$72BH38(0D"=)2D80.EAF;9"$C2/H1/EEA;%*//D1<F:#);4)AE%HEC':$H4,
@r5881
GATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGNCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCNCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCGGAAACNGTNCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGNGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGNAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCATCGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAG
+
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
@r5882
GAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTTATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTNGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTNGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCG
+
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
@r5883
CGTTTCCGTCGGCGTGGACAGTANAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCNGATCACCTCCNGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTT
+
3%1)"A!5=G6F&4D'7;=!*ED8B2(72+E',H7,@%>%)@G#,<<")+0C:A=,:8:2*$.%@?(<;9.B3875!5F9A:4(H."""8B4$890$%B+#2690;.:A@60";(??H$1%362"/=.;">+7$G30;&6<,(8'DD2$-<91-F)
@r5884
NCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCNGGCCAGCTTGGGATCAGCAGCCTGACGGATGCG
+
!G+&5?=02=6D'4)$49BF'G:><(-2).,81DB0F*)E/4*F%*59%7-/)BEG*$E%8;@#":A5-6C936<<""#)&;7<5%H#:4DE:,66G>%F6;2A6%6!>0#;,2:$?/>1.?@=5<5=--F:H82-EC2@=;#;)'H+?,E;*<*,/;;D,7:5
@r5885
CATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTNAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGNCATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTN
+
1H7")8.;$;5C!>1#B(F8)1.#,41@.=#3*?-4"08@$G?C63B(;&-;##0(G;B0(4==:52H>2C3C.13A443D$89;*'>5G3#6>176H:(,5$E%%9H+.%14+>-3)>,:F<'C6,?ED74<:0H?+0%3HE0!&!%C(A=27&;G64*23%7&?6/!D,:<BF2+C@<G0?/1#32
@r5886
TGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAANTGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTAACGGGCAATGCTGCGAAGGGCGTTTTCNTGCTGAGGTGTCATTGAACAAGTCCCATGNCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTNCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAG
+
).E%>%$?F$D9F7%%CC#E%<%+@4D2,FD;>G!,)F,@);,"8A"1D4;.7<BG*-,/E$$)2G@D/9@BB2@E-B82*!>A@6&1-G47-4GD+(.(%<;G2GG9,-)6B.>),?%'3G,39B16+)0H(1:6%=8B;D*#5>EA=@<&"')66/5B)G46-#%,EG".30?8:C5A"@@EB01!8)-G#2##7&%>)>G(A8/%/?E;.G'%37@(5)F)2>BD7$9D.F"E+&='6,5&7<2E0*$H0D2*D8+EH3D4(;'$1/E(7=74?>?<'6D/".%G2/!C?*,1&4CA,&>6::DH6=B@$/=1:E2/BAB%<4A<;)B;376;&%38A41-'(#>(06EE#,;=5257/C7A<)-*&B,@;(*2H64E#)DF/<,6(!!B)H"C)?=>09)2,&.9FC2237&@&-:#:D&E;E3A%=4+&1:C114)$!"(9(E,?4-"-/HC259-$4"-4->2H2D=@,'(0F(0:"*6264D+
@r5887
GAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAA
+
H1>1B;-H-5FA6#-H!<EG:F*G>15$;**,>C>!D)F&=HG4?F.D@D.4G.>#CG?=F*2:*HH%8<61=D.!9;E)5&<2-685/$1<9H:1;F%6@>3(0?<&G41A72GG6,(9!B%.$7*''H;&F0;?0B+8*,(:2#B<B!6
@r5888
GCGCGGANTGNTTCTTCAGCGGCCTCTGCAGCCGTTCGNAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCNTCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGCTTTGAATGCCCGCGCAGTNCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGNCTGGTCATCAAACCCTTTCGT
+
($%)&&&"&&#'"%%($###!($'%$$++%+#'*$+&%(%"%')$%$'!)&%+*#"*'%!$+)''#+!"*)%'*%))!(+'!$#&%!$+''"%((!$#$#(*+!#+'(#(#!"'%#+(+*"*#$%((**#!$%%(%"&(+%*&'+#!&!!!)!("!$#!'+!$+#""+')*!$$&&&*#+*$'#'*+#)'))#'($'%($)")&(&$&"$&+%!$*'%&)&('*"!$*"!+'%&!"+&)$"!)('")%$)''($%*'&+#+&(+(+"*#'*)!)##(())$"$''()($%!%)!'(')*#%)#%!$)%$)&')%*)"'*'(%*%&#))*!$'+'&#$*&$%'&)!"%')$("*!*''%*"&#($'#$&'"&)!(%'**!&)*%#!)&')"#("!&*$)'%$&"!#$!#*(!'"$)')*#(+*%%
@r5889
TCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGNCAACTACNGCAATGTACCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACTTTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACC
+
=F$FF:3'?'!-$)$)!5'/&!D)$C>-<-@G>F4F&;?>+F1/EG/H-3/48F4C.%3&.4!):/9H#29*"-.8DB#(826:.+<4)5!$#&<H'=F$/.A1,D37FC56/?D>3:HA)F@!*+&-G,;?>%$8AH!8&."F5G#0190E10(9(?/0@@C5=5F/:F+'2$43#H*H=.+=4/3G#72F"=19#BGAE76<7%678#C!731-BB1E
@r5890
AATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGACAGTGTCGCACTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGANAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCCCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTNCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGNATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTNAT
+
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
@r5891
TTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGNTTTTCATAGATCCACCCCGTAANTCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCNGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTANCGAACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCA
+
"<&'92(D#==8/1.+C3:+=;C.C@,?3&;/C4&.<7A"C(@H%#<"0;@G17%+=57#>GB%B2<-;C<5C<GE3+41&57&%>)8!7$D3,D=D+-'46'GD<=$+62>B6#@CD0*3H&=4?B0/.;9@B2A!F!H<56)D(!<%;!G7HEBE,A2/$&+&4A"5A+%4*)85<'/@'!%93,A(3&"+!@7+%DA7.2E7E"-49;D4?2DDA%?'@(H))45&E%=<?$>$<.#D)8@?/<G=00&>&5EF59A!0-C@$.+(G692:-69HDH0(C#)E@,#H@!""6<DF>$E4,$AA03"9B##!>+64H>'(.&$0A69./HG*+<;&G(;6)*<H87$*-2);9%)B-G&B1E:BF81$E,4B.$586E2F4;;1%A$G1
@r5892
NCTNANNCNNNNANNTNNNGGATCCANACNNTAGNCAGAAANANCCTANAANNNANANGCGATTNNNGNGGNATGNGCNNGNNTNNNANNNNNANAANCACGNCNAGCNTNANAANNTATTTNNNGNCGNGANNNNNGCNCNCANGNNNCNTANNTNANCNTANCANNTGGNTGNTNTNNNNNNNANNNACNTCNNCNANCNNANNNNANCNNNTANNT
+
"#"$##"$#!!!#"!$!!"$"$#$"#!"$"#!$$#$#$""$"#!#$$!!$###!$!$!$$"""""#$"!$"!!$"#!#!!$!!$!!"#!#"""!"#$!!"####!""!#"!#!$!"$#"$$"""$!!#$#!#"!!#"""####$"$"#!$!#!!$!!!"#!$$#$$"$"$$$"$#!"#""!"!##$!!"$!!!!$"!#####"!###!$#$$$#"!#"#
@r5893
TCAGGCTGAGCACGGTGTACGTCAGCCCGNAAAAGTGCATATCCAGCAGNACATCATGANAATAATGGGTACTGTAAAAGCGGTGCCAGTGGGCATACTCCGTGGATGAGATCCCGGCAAGCATGGCACGCCAGTCGNGTCGCCCCATNTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCNAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACGTACCAGACAGCCGGTACACCACGTTTTCAGCATGANAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCANTCAAGGACGGCATCTGCGTCTTCTGCGGACGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCGGGGCTGACAGTTCAGAAAGCGTGACGGTCACCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCAATNACCGACACNGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGGCATGCCGGTTGCCNCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACATCCCACATTGGTGACTTTCACCGTGCGGGTGANCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGANCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGNTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCAGCAGATTNCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATC
+
#)+!%&*#")%)!(&#$*)+#'#'*(!++'($)%"%!"'$''+%+#$"++*%%&"*)$+")%"$'&')())$$%#"+%"+%$()*))$#&(+'$+$*($&!$$#$%#%&+$'$!$)*'$&++&(!&#!)$+%*")%)##$+$&$*)")$!!"%"%!(*$"(%"#+!+('"(%%)%"(*(!"&(#&"+%%*)&&(($%'("'&(%$")'!+($%''*##&"("("*"%+'%#)((%'!&%'')'%#!*+*)&*'+#&!(')'""*")%+'"&#$#!&%%!*)#(#$)+%()'"#"+*'*"##'))""$'"!%&#&(&)&)%""+%$)+*)#*$)%+$$)$''+'!$'*)&)'#*'#!*(%#'++)&!%!+#'#&'#&**)%)&'$&+!!&%+#*+)*'!+"&#+!''+"%*'"')%*&#)*!&&"+$#(#)$+!!##+'(*&!+&(!*!#!!$!#)*$#"$%'&+')'*)+")'*$!!!%'')(!(!!+!''&'((#'"+!)'&!'$%)*&)%#)#$!+*+&"$'$#%'*'"#%$'!+*!+(!"$%&+'*(+'*"&$&&!'""!'"!!+(#")!)%!($+)%!$$'""%+(#%&&"!""*(%&%'**$++%'*+'*+#%+(%%%)($*)&)"*#'"'''$$#!)(#"!#'$*%"$&'%((+%"#+(#"*+"++*&(('*($**$)+'!&&$+"'*)&"%!(&&)")%+'('*#+&$((++%&)**"!')+&%%!*&"(*$''#!+#$&%!+))+$!$''!(#!'$(+%("#$&&%(#!!+$#!'*''$#!"(+%&!'#+)'"""+'%"*#)$!((!+%$*"%)**#'*+*"+))%%&#"+("%$#&)"!&%'!"()#'%$%%*'*'%!&+)$$%%$%$+'#+($*#$"'**%%#"(#&+!$)$"*)#$$'&)*%''&%*!+$"$"%)&(!!(%$"#**$'#&!$+&"*)'*)*$$''(##"'*+'(#((*))(!()(*(''('(%%+!#")(&&%"$!'$%#')#)#!!"'&'$+*&)!()#)+"'+&')%%*)$+'$'#!'&''&&$!$#$(!+'')(($!!'(%$+#(%%(*'$'+%+#!'#%(++$%(%""!&)"*!)&"!&(("('&+(!'!'$*(#'#!"(+'(&!'+*$(!+!"%#$&##%")&&#)(!%"%"#)'(
@r5894
AACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCNCAGAACTGATGAGCGACCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGGAGAGAAGAAACGACGACGAGAGGAGCAGAANCAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAAAGACNGACTTACCATGNATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGNCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGNATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGNAGTGAGGCCGCATGACGTTCTCAGTAAAAACCNTTCCAGACATGCTCGTTGAAGCATACGGAAATCAAACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAANACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGT
+
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
@r5895
TGNTNTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCNTCGGGTCATAAACGGCAAGATGCGGCGCGGCGGTTATCTGAAAATAGCCCGGCGTGAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTCCCCANGCATTTACCGACCGGACTGTCAGCCTGTAGTTCCCCAGCGCC
+
%&)+)!$#!")!"$&))(!)*+'(+#('+)!#$'#%$*'&)#*&++''#')+#"&$*&!#%+'*++#%#!)&!(&+()%+#)")$+%%%#*!#()$$&(!*$"+&(!&$!('*')#)!+!##)(*+$*!(*$()$')++&*#%%&*"&$%#)++#%#*'*!''$'(+$($!&##$!&+)!%($*%!#%%"#)')&'+)('"*'!%!'+!&*$)%$"##&!"&*%!&&&!$#
@r5896
TGGCGCAGCTTCACCCGTTCCGTGCTGTCNATGATGACAGATATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCGCGTCAGGCGGT
+
;>.#D2:H,AB9;2+:3-)26A2)23'.;=7/@EB<E0(6+C02FE87$3#!1?,;$%;F/EB/<%"(7,B-G(!(7/032.C9,/32'1+1==$5"0!B&4:+G<(77.5H8>(.3A20*19GG8!$<*"):,
@r5897
TTGNGGGGNNGGNNNNNNTGNTANTACNNNNTTCGTAGNNCCGNNNTCNCNGNCNNNNNCNGNNCGCNNNNNNGCNAGNANAGAAAATCNCTGACNCANACAGNNNNTTANGACNNNACNANANGNNNCANNANNGANNCANNNACCTTNNCNNGANNNCAGNGNNNTCGNTNNGCGGNCTNNCTCNNNGGATNNAANTGNCTCGNNNCNNAGTNNNCNNNNAGANNTAGNCGTGGCNA
+
$"$!$"!!""$#!!""!$##$!#"$"!!""!#$$##$!!!#!#!!!#$!!!!!!!!!!!$"$!##$""!""""!$"$$"#!$!$"##$##"#$##"$!$#""!"!!!"#""!$"!"$!#!#$"!"!##$#!"#!!""!!##$"$#$$#!!$#"""$$!""$##$###"!!!#!!#!#!!!#!#$$""$!"""#""$"!"$"!#!$#!#$##!"$!!""!"""#"$"!!""!#$##"!##
@r5898
TGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGNGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGANACTGAGCG
+
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
@r5899
GCAGGANATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGCTATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTNGATTAGGCAGAGACAGGCGAATCCCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGAGAATCAACAGTGCTAATTCCGTTACGTTACATTCATGGCTTGATCGATACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGNCACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGNAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCNCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATNTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGNGATTTATGCGAAATGAAGTGGTCTTATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAGATGCTCTCCGAATATCAATGAAGGANACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGA
+
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
@r5900
CATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATCCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCNCCAGGCCAGTGCTTTAGCGTTAACTTCCG
+
5'9,/.DG4%:7A:>6,2+>'"55/(.))8=!D2#'4G=06H,<8(G:*:7'B>96!3%#8)91493*.'66/:;?@F?7.2>#1!1?D.:<6?B8-C5H.0=*A/$33$GED1+F99EC>5+@'/A589""4+7'3/EDBH08;H-
@r5901
TGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCG
+
=5>,9B412E,!7(64?<5>*0'G.&BC7/F*5)//F>(/)G71>E7=+25C6C>4:.&8=B+AF94B#D>,E)1-9@5.>7(@,*A'%53G/DH&B<D=-,<--554(/E169','0+G?>=H,%5"+2<FE!(-/6@#.-B0A/*&'76;0(3"B.-
@r5902
TCAGGATNTCTCNNTCATGNTNNTCTCTATTACATACGTTTTCCATCTAAAAATAAGTAGTATTGAACTTAACGGGGCNTCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTNTATACCAACGATNTAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTGCTAATAAGCCGATAGATAGCCACGGACTTCGTNGCCATTTTTCATAAGTGTTAACT
+
#'%"*%&#&#%("()#"!$!($+"#"+$"(+"$)&+*(%$!$$()+")$+(&)!))&)#&+"!($***$))&##*')"%"!+)*!!!(%(%+&$"$$'$+*$+&%)*""(*##!$#&(&$)"'+%(&%"!')#"!)#+$*+)$)+"*')$%"#"##+*++)'%&++(&&"*%!+("(+#*#'+(#)"&&$*#(("$$&"%%$#++!#)*%&)#)%(!&'!%+'"*+')'")#&'&"'(+#!)"*'#$(&%*&)"!!'"$%+**+")+*+&%"+($)&%&!#(#"$$'(!*""(!(*'"!
@r5903
GCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCG
+
6;<D.$1H=2)./3@.7DB(%%65DH313*+%#1(A)17!9H9@*+#'E=?+/BA#?!3*'9,)E-)>;6+&E;"/(=:1)032)E<C,<4@1E5"'/=2-C(&4>'4%671,FDB/)1D)<HH.6
@r5904
CCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAANGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACTTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGATTCTTCATCGAANTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAN
+
3*;G2%=BG>@.0B7:+A33*A5*+'2("&+$G''>F3*<B(?HD&F+@B2*C0!;;84>:H;H81G6;A0<G6.0,147D,B/--,>>,7G;,@;1*8$*0'"@D8'.E>'%6/6?22F3HDF7<0)4%F%)C615!0/C:!G(<1,*AA243=BEA230#<"#3&,E=0?E4>9&,1DB-(6G==<H;@=7?=76#?).CEGF1%)G@@/7+'/@3@-("",&34C-3G-(8C;:G?&F032657D57H5BF?'@@(CC@/>9%<1AE2.F*$A""./E!A,&E&4HE?#=?*4<=(D/)?7C;A!@4/&!183#->/-%E,B-="B-:4:H$)C)AEE3;>@..$?;?&'5D)6!$-:,5
@r5905
NCCANTNCANNATNAATNGNCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAAGCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCA
+
$$)$#'$*#!%&*&)&$"'+(+!'*%'++'$#!&%!(')*+%#''#(*%('!+**&&)*$'#++"""("#!)+'+#'!($!%!+!$!%&)"&!)(+!#*##'*&)'!"('#!&*%#!%!#+'++#*(*#+)!')$"#'(&)!'#$%)'$**)*
@r5906
TCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCGGTCAAAAATCCGCAGGCCAGAATCAAAGTNAACCGGGGGGATTTGCCCGTAATCAAGCTGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTACATCCCTGAAAGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTANCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACNGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACNGGATGCACTGGAGAAGCATGACACCGGGGCACGATTTNTGATGGTCGACCCGCTGTTTTTGATGAGGCGNATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACATNGCACGGAGCTGCATATCNAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCAC
+
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
@r5907
TAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGNCTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTG
+
,6!=/;"-&A+=-FF1<?)7;#$E78&F72,A6"5$@*:D'!)H'HB7</D<FA='?@3H-6$(=56</&(1@05HF%1""4
@r5908
GGGCGACCATCAAANAACGTGCCCCGGTGTCATGCTTCTCCAGTGCA
+
+4(5/?."+982H*!:+$HG=E056*?D64='=D&(G5>9&%FG/7(
@r5909
GCTGATGAACCGAAGTGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAGGCAACAACCATTCGATTTGCNAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGNGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATAAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCNCTTGNTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGCCTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGNGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTNACTGGAATCNATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGANACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCNAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGNCGTGCGAGGAAAACAAGGTGATTGACCAACATCGANGTTACGAACAAGAAAGCTTCGAGCGAG
+
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
@r5910
ACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCAC
+
C'H=,&C!H+"#*'%F!4G4C)<!96GH8=%:<=D=8!C$7H#'8:C9*>-/2$>';D!#DB9:E08D;90>FB:@?#.!+=F<+-%=AD*6-=G:&-A?<D2F@;D.*/!"E"@'$B:19,/AE<;92$6D+(H-!**H:%D"8$8=87C+6=H$EF&:81G=?@0,3$3*&E(15;)6(;>>81D+68&=36@'4<5F##.G:=C<5D+"G,.$""+BGA*3-'="2G@*B:6<:0%)H61
@r5911
AGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATGACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGGCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAACATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCCGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGG
+
"8<D!%EEH""#:7.F-;F/A#3=,'@97C44$84(-+230.F!+C39>-<F3B'%=;H/D+'!,(<AF$(9*$@.@!%8$&=;$<6G7F!H06H@"1B4C,B".20::A7A</%F6#(@"/?A@5.3<::&?A.)2!6-*E>-:<%@1!@F),F8A?H:;H*(125>7&7./,/*="@?/A>3D=@%@92'::H04'C2;5?=E-.F@&(+:C,C(CH/=C6A(=01'!#/G)<9;<FH$1EG6G.'@%E+8@)%C-.=><,>:(,0#!!.F92A1F<&%D65$=7;5"=.F81B(+'!G.&2*AB*:;!7%H'*/HF/'4(H5:&6$/58A!C,-."=>12>AB>H7<9-(2+E7;?#(2%(/=>:B49;G==$>(?$+4*;>GA*C*$/15)<!H7,CE)9>'?DG;H61-DF?)8E!3C;$/*#<6
@r5912
NCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAGAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGNTACC
+
"A"#!'$?;<0!1C;,02D(*1+E/600;30'+B;)C"77>.ADF6FC-A$=-2,4-,HA'!HD#&#6;#GC-,=F3387(72B(B?/:B'C676*#>'FD'C<CGF:").*#47?3:H!?!@59@&(.88:>G;A+G&21(%*F4!2,&@+D.4E2=$
@r5913
CCGNNGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTANGCATATTTTTTACACGAATCAGANCCACGGAGGGATCATCAGCAGATTGTTCTTTATACATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTANAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCNCGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAGCATTCCTAATATTTGANATAAATCATCAACAAAACACAAGGAGGTCAG
+
)'#!"+&"'+(+%(+(%+"&''$'*(*))###&&'+!+)%%"')#'!+'#+$%$$)'%)+"&""&*+%"(%&)%+%%")&)*%%&%'&("'%))'(*$!&%)!()#!&("*)!$+!&(#**)($$%'++)+$)**+!$#()*++!%(""*"#!"#!"*)!!'+((##$#%&)%""*&"#"$*$'*"$!&&(++)"'))&$'+'"+!)*!&$$)#$$'+&)+*+!*('*"&*&&$*)'%')+$!%!%%"#&*'*"!!%!*$!%"'#&*)")"$$(+$))#(&+&'+)'"&*&)("'#*!$!(&(%!!$#(#(#+%!%+))&$"$**()+)#%)!(*'$*$$%)&'(&!
@r5914
TGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGNTCCGGTCAGTGGCGGACTGTCCAGTGGGCTTTTCTGNTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGGTGTTGGTTGCACTGCTGAGCNGCACTATCCCCTTTCTCGTNGTGTCCGCATCCTCAAGCGCGACCGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTNCACGTATTGCCGCCGCTT
+
1'(:(2@#*%<45"@=&F0"4AB4A4DCF<;'=,E*@$&9C),+E"?E!GD.E,6D5127<%C+9>5H?<G=E,4+:C1(*2=='C+H5&$2H?/:<C6>:$*A@F)CG7+-7!:,9.!>@$0*-&H4##'#<;DAA*87'=G-6?=1A1%3'+'=3!,4464"C=3?$+$'+4>(:F74@)3C<@7'%:6+FD=F+H<2#=!E($:*41B=6$+0?280%9=($C.6#$D3HAG(G'"/BD&?E:7'>"")!"%H9
@r5915
TATCGACGTACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAANAAATGGATATTAATACTGANACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGCTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACACGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCC
+
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
@r5916
ANACCGTNTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGT
+
%'?;7*C8+A+!3E7;#@3:%'F4B#E9;:;H7>7E&.*5'">=7F)=0?05++C;'#A#$#9)A/41BH.-79'$1!2FH&D2*">08'(=F5+-(G30'9%A<B%@:
@r5917
TTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGNGTGTGTTACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAA
+
3A./<1-C5FF@01''E#.GC'5?%(9'=E-/0AE%G9H9+A=2+28G/@H0D*H7G"G%/+3-H0:.81D#-6'>4:9%3#%"<D'390*$&&%.>-A2A68E8,2!F"..&490.5#8:>!0F"1(404'?;&0*)+'G//?0B*"1!D&.))&GBG<2(A/52)C@$.?C7E83>:$=9,7#?D;H1"67-A:
@r5918
NACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTANCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGNTGGCGCAGCGTCGGTAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGA
+
&:E>>.74/(+&;54$4!:'E80;;.-@8;A%$%4<0<=A*0E/(544F@5H7'!,<:>9H@GF-6(':2B7'C>0-'E.(,",H$);<)0F&(BB5E-F@D6)G:E;60C22)$64-'DC;-6#C/A@1H48:A9E<2*1%/>'!7E6!9$2(<C@E%>,'/':90=#',7D6!D!/8#=47@H(*1?2C6;853,H:.
@r5919
GTAAAAACNTCNTCCATCGATTTTATGAANATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGNAGAGAATTAAGGAAANCAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGNTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTNCTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGNCGACCAGAACACCTTGCCGATCANCCAAACGTCTCTTCAGGCCAGTGACTAGCGATAANTTTCCCCACAACGGAACAACTCTCATTNCATNGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATTACCCCCAAGTCTGGCTATGCAGAAATCACCTGCCTCAACAGCCAGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTANGCTCAGGTGAGAACATCCCTGCATGAACATGAGAAAAAACAGGNTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGGTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTNAATGCATTGATGCCATTNAATAAAGCACCAACGCCTGACTGCC
+
)#$%(((('$")(%&%&%+!(!#%'!++!$$(+*('+$"!!)%!!*!'!*(!**"(&##($'"&#!'!($!*")&$"&$(*#%)"(**&"%(#+%&!&("&+"))%+'!('#$%*)'%'++###"(#+'!)#!+""%$*(+)%(&"('"#+"#*"(&**$($(''&''&''"!'($!"&&+!)"(!!$+*(##+'$'(+)"!"($+')$$!#%'(*(('!'#))''+(#"")'"#*#+**"#(&%+%(&(&(!'#$&)(*&+%%*"#)&!$")"&%))&'($*''!$!&$&%$*)$+'(+#&"'&'$&&#+*$!''+#%*(('+)"'%++"!!%*%*""&'%$(&##$+&&'%&$***)#+"&(#%!#+#%''%"+#&#+%')%$!$#+&+!+(%#$+''%**%!''!(!'+'%&")++*%#()%!&&("+')!()!+(*#&(')'$&!'(&%&%*')%*!$%&$+%"&'%*#)%'&"'!*$!#&"$#!(&')(+'&+*%&%&&!*($(*+()&%!"**$&)"'#%+")(")')#&%&+)$$'*'!'*'(*$!(***'+!%')%!+&*+*'+)&""#!!#(('*'($$%+"%*)""(!)$'$$"$("")+)&$'%))""&%#&"#(!#%&&#"(*!(%!%#"&!&!*%"&)(*(#$"*"$'!$+"#!#*+!%()#&)#+'*!!()&(%+)!!*(($!%)$)&!(+#&!%%##!#'+%")+"$"$)!$#*+"$&*()%!'*++)$(##"(%'+!*&+"+$#'(%("+('+(()"+(#$&#)")+"*$*"#"(#"!"$*%++#%)(+(#"(%$%'%%#('$"&+'!'#'#!(!$!$&*+#"'$&%&!+$!*$!*+*&
@r5920
TGNGAANGNGATNAGCGTTACCGTTTAGCGGTGCTTCTTCAGTACGCTACGGNAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTNTTTGATTTCAGAATTAGNCTGACGGGCANTGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCANTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGC
+
*"$*%("$'"&)"++%"%+""%+(%+'#&$%%"'#$$&#"+%'"#"$%!)#*"$')#"+'%%#*"#""&#$(($&%$(%*&#($''(")%&)!#''++(+%$+!)))'"%"&#(&(*!)"&!")$"#+**)(%"(!$'%#!!("%'$*$!+#)*!+(&$"!%%)$&()'!"*!!)++%%#')'(#)$+"""%+"*)#)#%$!!#'+("%)
@r5921
NGGNNAGTNACGCNTGCGCAGGCCGACGCANAGGAACTGNAGAATGCCAGAGACTCCGCTGAAGTGGTGGNAACCGCATTCTGTACTTTCGTGCTCNCGCGGATCGCAGGTGAAATNGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCTGAACTGGAAAACCGAC
+
!$!"$&$'"%#'&**+*&*$#!)(!&!'&%(&&!+""((&""#!&+*"*+'+&*+''"#%'*)+#%"""#!)&#%'##%+!'!!"""&*$'($(($%")#%+"!"*%!"'&!+!++")(!(+*+"+)*"!!$%*&))$(+*''+!)$"!"!+$(%"#)&")!'#'!&)#')!+)%%())++
@r5922
TTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTTATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCG
+
.0:)*:.=A$)(#0&#%=-FA+%!@"BE2$"+5*.@C/%:>8F+$GDC=7@-061A>:E!G1@B*!-36+/?@)*9FH:HD5FB0/.-G67&$GG5E%-D4,85;$"87'*#$?$9;=E'*1E,<"91,31F@3)/9.*F?"C);&C0@>!<(3!4E!.)B;B#'*;)**4
@r5923
GTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCNTCGCGATATATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCNGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGAGCTTTAGCGTTAANTNCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAACTAAGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGTAGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGACTCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAANATCTGGGAACAGAGCGGCANTAAGTCGTCATCNCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCNGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCTTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCNATGCCATCAAACTGCTGATTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATG
+
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
@r5924
NNAANNAACANCGCCTNTNNGCNNAAACNGTCGGGGAATTNCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATNAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCANTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTNAATGATTAGCAGTTATGGTGATCAGTCAACC
+
"!&%#$%')(%$*)%('*!$%#"##)""()(&"+%)*#+&!)%$#(!%$)'#"$(%(('")*$!$+(#(*+&!()#!&'')*&###$('#&$++"*+#)*%%"!))#+%*'%'"!$*!!$%!#(&#$''"'!&%++*")#"+"$+&!#&!#!!#($'&*'&*(((+)!"&&")&'%#%*&&&"$+&*&'"&$%$&%!*""++"&+'")!++*''!&&%*!)"$"&'*"(!(#!'$)"+!#"#**$("("''%#'!""((!("#*&"%)')!!%$#'&%'&&')%&!**$)&$')%#$!*&
@r5925
GTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGT
+
-?-#-FD"".D,F-.489ADD9#'4:37;.<<H!@'.//38'."6(C>4:0**!A%%CE&+>;F?:+H-*5:*F$?E5
@r5926
GGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTGGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAANTTGCGGCGTGATTCGGCACTGATGAACNAAAACAGCACAGCAGCACNTCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCNGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTNCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACNA
+
6E>/(#H(0D7"D419$$8>B@,2A:E.=E+7D./0*A8C2D43*A*.!'B$=/B($/EB55:2'>"5.05!6))<'83??E'1:D@F=-;B!#80),#/7CA+.F":3=@,9%;'#5"96($E7G..$@AD79EE7;14B9(E(5/*:8A282&07"F7#*).054F9&#@<'":6H+0(/?5>G!8#5FB("EB+<-F'3CF)("%H>>D?E-*+C)G(+D5#H56=*?9B,AFA-C6'0A37G9;;2'+E$$7HB81:7EE:<C,A';C'F?D<6;!GAA84++C/;29>7*A8!H))C5-=D64BH)6>)?6(!-/8DD2?0-D#/DH#(*)0!?/H;=!B@.(A,'.$FED0)@0+%#3?;9F'.-<=B#3EE%)5::7C<#?:6+#9F6$!4C15B1:=2.-5(4>,%-A)3<6"1B7"GC<44*:/-:,H"4%!B@3D19GFG/:6
@r5927
NNTANNATTTCGCCATAACTGTAGTNAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTNCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATNCTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCNAAATA
+
)#(*"##'*%&)$+$*))'!&(+(&#*%)#&)*$"!)!*("#"&%"&"$!*"$$#$%!*$%&!%!""#"$&$'"!$*!$##!%))+"%$#'+$$*(*'%%!#))!%##*!%++'')$#!)")$)+)"$!)+#***'!(%(++(!*%(#'*+&#($'!&!+!!*($%(++!##)+(*&+((#($!$!!""*$&)%$+"&+'!%!&$(!!)#%$$"!'#($$$)+&''&!&+$)%!$)!)&$)&)&))%)"'+*((*%''$$$%$#%%'++*$''#&(%')"+"*&"$)%"!*&)%+$%)%)%%()%*)'#'$&"""#'$&&*("(%$&)%+!+!((+#%!'!(!+)'%'&%!!%"""!&+'$!')#
@r5928
CAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCGTCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCNCCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCNTCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCNACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACGGCGCATCGCCGAGNAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTG
+
+!EH*.+'C,>3/3+H8B<;(14'CB11(A71%'4,A5H9'!:'D$';$E%(&<,"F-G)HD*BE>;--?EE"&BG=+C'5B3()D)*3?<A!FD:>16)2"-AH/0??+0D/9F>DB"-)&+./8#;G)/#934BG78!'>G:3&$C=+6@9:0A4D+;5?G(&C+,>4:*'F+9B:(E64:+.:3!;H;*%CD)'E.F*HE/9"7;$5C+!/E:A*$-G,(H'>%H(H7?D'+$,'".1,65:H'6+&>?@'EEAB:$293$CF@"$(%=*);1(-04;)(&#'@A700%=<)#3>:=E(#88GGG5::3&)30=E=&!-%D%((4/:043H-"<D:/C'6.:0&E&-F>+!4(
@r5929
ATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATT
+
'5<C:.G8C.>!@D$9:+'5800DF%;G"&+97@-$G$E>F2$<7H9-
@r5930
TTGACGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCNGACCGAGNCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATNATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACNCCCATTAGTGANACGCTTCATGGTGAGCGTGTTATCCCGTTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAG
+
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
@r5931
CGGTAGGCGATCTGNTCGTTGNTTTGAGTCTGGATGCGGCCTGATTTGACGAGCAGATGGCCAGAGTCAGNCGTCATTTTTCTGGTACGGAAAGTGATNCGAAAAAAACAGCGGCAGTCGNTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCNCAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGNGGGCAAAGTCCGTGGCTGAT
+
2@148(*27C5,,9+B2+##,G,#1+*+0B8>*E1.9+H<9GE@'*)+=((9D<#5-$D!5&50#"=7:2G427&,G@HE+=:2A95A2,5-6<DG$>*E7+"%)!A;G;*56B$,5E;*?7"@;<,@$9-3=*".-G;.")('"CF0+#"847D;H476&-4-'"'/>F&<'G/4,H:>:8'01.,7<C61@%<')?@=!!3D?65+,HB>91-1;9+&1$&(*B,5*;-H.5AC#4$@-%4+D8C'&=FAD*-)B@32@;%F&
@r5932
TTGGNGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCC
+
*!$'$&$+)+))((&"))&&#$"#$'"(%+$""*!$%")*$*'$(!'*&")&+()(!&#)$&#$)#()+(%')(!"#(&(##'!'#)(&((&!%""*#&#!"!""!((&###)'!')"$))$*%)$%*!*)&)##%&'(#)*#*(%$*""%*!"!#("&%((#%*#$*#)&(#&!+*")##
@r5933
ACCGACCTCNGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGAATGCTCCGCACGGGTGCATTCATTCNGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCTGTACCGTGGCCTCCTCANGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGCC
+
2<;)4B")5>(CA$2!<$E:)63D5>)?+':B*<A>C:1,E$>,G@;H:0/0/E>42/@.<7B%A'(#'%7,";0;1*F>,5&>#G6@E#,"3/<?&"D&H?)&9!B*$!3:,,$?1G(D(';7/A91C621%GE2%-B=%GH6B((843D<.-'44/D("7F0C6>/@H"&/8@41@%$)!<'*2076H:!H>)=;%+9F.DF;'4)G)6D$&$C&*!#&?@ECG="%9)-=<@51&0E=)-=.534GE0G;;9"C;7/.08?%+G69,2C-."*F(+=&;#2E@:104/"<0(&ADB'3'D0?=9%BCD
@r5934
TTTGNTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATNATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTCGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTAATATTGNTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATG
+
0(4B&@.##3+H827&)0<A1G&#46=5<#A,@GF&D#G+33%<@1+.-""<@B:C"=@$-DB+)-(:@9!G?5D4B9-H1>:>),D$.&H:/6#<,=&F/3C03H6'5>7-+%0>2B"5C1?!9#<,-#':?G=AGE<*):2,;0)#6A424<&..6(=6856GF2.(DHEG52"@,:4BE02*<+E"B*-7=<=86"**A;0)3.39:=B<E#CCC78-2;(C@68<)$*.%:H=8F3G@90/,E<5%:+B3:)5E(HFA$4&9$=B'(0>5F!@D"!76@$/A*6#8C,D,=2*C.8*:A"?!'G-?.&*E,<F0&C63*,;->1#)13A;;%F"';1<2%6"/FG::1?C'35/)%!*;8'@
@r5935
ANCNNTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGATGTATTAATCAGGCTGGCGCAACATGCTCTGCTTATAGCNATTNCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGGTACATCAGGAATATTTGATTCAGATGANATGACTATCAAGGCCGCCTGANTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTCGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAA
+
&(!"!+$+%'!#&)(%(("&%!%**%%'+)$$")++&*!$(%##'+'"#!"#)!)*"+))!%&#$&)#"'%'"#"++)(((!+$*"((#%#)'&$+"''$!(&#&"#)'$#(##'(()+!&+#(&$(!)"%!"+$$**#*!&&+$%"'*%+')%$"")"&"!%+*)'$"!'%$""&*%!&*+&+&*(*(#%%%*$*(!$'((""*(!!!&'**+$"($+*)!)!!$$!&("'"$$"*"$&)%'!)&%&!&#%%#*""#%)''''+)*$*$#+#%!!$+#!&)))%"&%"'+)%"!!)$'*#'+))$%)+*)%"%*#*')'*&!"&+%(')&*(+++&"$&!!''&)'$&)+*+$$*('(+"$%)##+#(')+#%%+!(+$"'$!*"&"%%#"#%(%(""*$!(++&!%++#+$'+'")*")")%%"(%'&%(*"!!
@r5936
AATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGNGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGNTGGA
+
3<3<6B92#D0:.F<H<E-=$,*B9"5"7*%C*???A-(9B:A4<D24C@E?D"'0*B@H51=@4"0E-&=G;@$48G#(116*D()#1'&+E=;=5%?G(9;@A"%&B,!@0!H$%4F*AB=16"H!()"B!F+8#!85'?)D=!7/0)&@16.!6%$#GHA)*/&G&*#6:E!D('&:,'A3###30G6%/%/!"G#B.H07$'-#*?$B<)C@?GF,,'/<>(@3*'5!C;87G/<*(2)<1G36BB5--86;881&0A&B2$8-17><)%15>,*@2?:(B=C(D:-:%!46;3=,=(+@C43=BAG60:#?B,$'*7F#97,34H"AH.EA)906&%*@(8.A1B8/BAF&'"!#<*-6
@r5937
CATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGC
+
3?&"8#H1>,"$5;0-95'1H.28(-"",7!<6:A<<8<@:*>"28=
@r5938
TNAGTTCGCNCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGANC
+
*"(&*&+%')'$!!&)%'($%&'$(%##"#+%*$!"'%*$!"(&"&*!'%*%#+$!#$)"&'!!')+"((+))"!"+"&#!)"("&'()%
@r5939
CTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTNATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAACGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAA
+
7A6&*C4!67-B#@@1/9:)A>C/$7&D,4!5-*6HH)*>'*<@8%>&)F73D9%@<#!8+B>B#(C;$%!6."#;!47+(6;CB4/)G798G3B0(#'/;>F&!0""2-.=1@.*16E,5?*=&3,B6(=;+(>/=>*3AA(.5H>DAACH.>=)F('(=BD2$!85E<)3#4);(*/D4@8>55;(E.062+67!!D(+*@:F<33F9/06-C$.!,,4+:.2$&E(17FD4H#3#6,AF68-),66>*'$.).:@D3)"F631-A4>)40HD<A&+(DC?$:3FG6/70%G8C509F957/;%=<D)'*8#$+9=,%$)/-
@r5940
GAATTACGCCCAGNTGAGCTACTCCACGGCACGGGCGAGTGCGAACGAGTCGTGGGCGTACTTTNTGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGNACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAANTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGTTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGNCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGTCACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAGCAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACATCGGTCAGGAGACCATTGATGNCGGACTGGCTGATGAACTTGTTAACAGCACCGAT
+
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
@r5941
CGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGNCGCNGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGNCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAA
+
;0'>+1;2F,HD2.;:F!9=2@:#A;("/;4:&?$4*D*@53!:'<0.F>,>-&D;+4:63,";3-CD89(A-7&$=;;$8A-1>C<'155$+!5,,BCFC712.840=6E0?).+,G)8=2E6:##*0#2&)>=4G1:97"8H7GCH44B(!,&H6H272)11/5D
@r5942
CCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACCTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATCTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAACTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGNTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCT
+
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
@r5943
TGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATC
+
7?*G@69?-6%3)8H9=62H?2/>$';C@-8B<H'1=*/0A'">?8#(7=@>2"-,-;+.&5!&,2,CD6*C3<H+4BBDD493,3'GH30B55.)#33F@H,/53>86;9C4":&?C75A*>1+FG)($#+,/=8%9BCC**2@D$!E*H4087B+8:E(=G27*$>HG@'C1'?#$;5/)$-7E3*(6#$DH>+7989=6+A/=A7+->>:8",5/)!&4E++,(1F=G@>3!<!<,1F(1<?<D6D*AAAC=*1%>8D$",A4@<301H9;7H,BDE>)2'")H?4'5;(5-H/???).2').>)>7D<6)4EF34*B:!;)0G;0*'527;<%%$"&;;0A'A%3+87EA7<(&B?%+
@r5944
TCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGNGACTGCAATATGGGANAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCATTTCCGGAACTCCGGGTGCTATCAGTTTTTNTGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATNTNGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGNAACGTTTCAGCAGCTACAGTCAGAATTTATTAAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGNAAACTNGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAANATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTNCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACA
+
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
@r5945
GTAGTAAATATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTC
+
4AECC"A484C/+58<*#)&>%9,H?1>5@1E.-455FB3>)92-'-7,B
@r5946
CAGAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTTTGCTTTCGCCACCCTCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTACATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATCACAGAAAGGCNGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACNCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATCAACTCCGGCACGATCTCGTCAAANCTCGCCATGTACTTNTCATCCCNTCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCANAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGNAATCCCGGGAGGTAAACGCGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCNTACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGCTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGT
+
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
@r5947
TGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGANTTCCCTNTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTGTCNTCGCGGCACTCTGGCGACACTCCGTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGNGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTAACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTGCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGANAAGACTCCGCAT
+
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
@r5948
TATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTNCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCNTGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAA
+
F.='"*>7?<#@C=@6.H=5A1HC9!-,1-<20&B.CH?-"H7$.71*6+HG$+3H:;;B-C-F!9/=E3#"%3%!*;$:1??-2BD-8-$;!=8180'<8:!'04=?)@3.+'>&BF",:76@=>-G,0#F6CB!.6B&?98/*#,&5!-3B:=A!!:?GF?:7!'3FG4!#-#,-9H56/7"1/:7<4&)E6+-*/G"F?*C+DG%"G'EF.5%G3"/)'@/97;>,ADD$(&'%#'!,ECC1)$AF!+F!=;*A6-*G$,F&.A:GH4<#15@-((0"C/F$<=*C/),CH1&=326-?"2')(37D/%G/0/@ED,('&1DB)GG0?C:+5(@17.@F"EG+E.:=6-H%>/
@r5949
TGTTCTGATACAGGTTGGTANCCAGCCAGTAGTGCGCGNTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCATCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACNTGTTCCATCGTGGTGATCCCGTTTNCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAANTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGCATTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGA
+
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
@r5950
NTTAAATCAANGCNAAGNNCAGACTGANAGNNTCAAGTGTATGACGGGCACAGAGGCAATT
+
!)$**&$*"'*(&"**'#%*$'"%$)($''%"*+!+"$!('("!$($+((+('#%!)*#&*
@r5951
CTCGGTGGTTCTCGTGTACCCCTNCAGCGAGAAATNGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTNTAAGCCCAGATAACNGGCCTGAATATGT
+
+BA=3H)+?)"A)(8GC9.33F@;;&3!6,>0$<5F+E7:F4<$>**@>/%3:>#"=A.%,+'5#/2-*#<'(1='G"H*2$,A(#$5?63<0G(579&1G384#80!>27<7*0=9BG'$-(584>)(1D,+A3.DC'+2E<=($60C550H@4266@228!;;55@0914>-8*+$;+2B/(..2*<EC>1B41D#6
@r5952
CTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAATATAGTAGTCAATGCTTT
+
(673@3AD8*.0,#,D+!H3A$1?:G>:==&4."B,8(>3E9(D23@>1@+HE63%4#(0H8A%*@3.>.@B9.+;50'%E/6$@$7#G&E<&%:)8:)B<G+/A7)'67ABH@9<6942G>G>3,A0"$$!@).H
@r5953
TTATTCAGCGCCAGCGGATTATCGCCATCCTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTNCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGGTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCNGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGNGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTNCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCANGGCAGCATGAGCACTGTCTTCCTGACGATCGCNCGCGGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATNATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCNTGACGGGCGGTATATTTCTCCAGC
+
1!8!6(("(?6F0"=B5**$>"6-A-7F199<+7+)7<';&-3<:;';GG68H@:(<(($1!<0!(C)8#6,(<E0''D+F3>/!"#%3#F9AC;*!<3.A>/C2#<D'D'<@A0!4>6F3/<&F0*<>0-*F*360--0-B1#;;HG>>=-3A'"';+<F7+H"CG*8A>+DHG,73;.G@$;>#1@%=!>6=FFCG>(;30?.8;'GG4G7B<*D9'*+57A*(#F?97>>6)0?<6=CB4E"5+!&-&HHE63D*84*C%-&C"&F>,A)5</G%!>2!GA!/EG94,(B8E;4HC-&6F-&04C17F6E64E+B&68'B$EAH$+13-1')%,!/G5#>D-&51-&.8:./:49/'6%HFA!!#GB?(652(7.<8FAB$:':")370-AF@#0B;6?-3%@+64A)04,CH0$850*8'CBHD!:%33,,E?A:+;#3<-33:8G;!C;(EF3*=B$57=;-C@*#3)G1=BA52*+/;*150@"0/?8,7C/292(+6G&*2!<'+G%3=D3E(%6'E49.=.;,!15275+.")0)0!5?+,438>?D.3/927>?&7$/;:!?$4%HG!'.7$%,),-*)7F#))3=7G
@r5954
CAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACCCCCACAGCTTCCGCTGTCTGCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTNATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGNTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCC
+
G$@2#>C0B/:F)8FE6H)C,=+9;/>"&0'14B8,+4E;7BF9F52*D2E30*.5)5>782G;-!>'!,(3E7<GD7804)3G+"/(+8,F59H-6AH.G*651E>%<#!BD4@!<,>-$H+D@/7D01@D>.83,2*$9D'E*!>,56$6&@>7!&?/CC<:3<27.#;&,7>;3'!%<+20CH=?2A<55*C0H*8#5%/<%?&%@#(5A8=BD)"*"H(?GD:.."HF#!D1$G-6(2!"897@,F!*+-$11"G>A%"/!&!D5(CF+<(6C3<.22'BA5F)H0.B58$</H31#A.>%<0%1(7>@*>BG615$,*D/>9E?D*27=A82;4C:4+./%/1'/B<;7'?2(E;@@>G*-=4?!0:7H%&"@3HGE<%*'0,"@:!657CB#CA@$>#$8-+:%>,/8(3!5F1!#>0$/DFH>FB"E2!5+
@r5955
GGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGNCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGC
+
&C0B?*;B$1H08+#7$*,C5/2<05<@,?4=9/.#.40>C=6F77"4?'D.D?+E==C%C;@4-=+;H2=+"98>B81319<%#71C2'$/93)$872D;3F/:&<#@'9B<8&95E($-?GH8DD/43#:F<9H!
@r5956
NCCATATGGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATAAGTCATTGGATGTTCACAACCTGTATCCA
+
&*&H"D7+46$(-*'2?4=B2?"1%62#23@CG7619;%"=")?40!2H:=0->$=>51*$*'79=+@$04//!F2$=73)>FBD,?/3.$9-*!/?!2B'<)58=G-36E%H=*C4GC,<2!AAB;>5+C"H6>#D+E'<E17$6G#180+8FE)@358BH7)*-""4+=2%>B)D@@83<'<=%2*H1
@r5957
CATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAA
+
61"8@$"C;%D?3G<-'A!(/F'-06G,C3,'55#6);&''2HB*G6
@r5958
AAAAGGATTCGTTCACTTCCGNTAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGGTACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGANTTGCTTCAATAAATTCTGACTNTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCTGAGTTCCGGAANTGAAATTTGCATATACCCATTGCTCACGAAAAAAACTGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGNGGCACGATGGAACTAAATTAATAGGCATCGCCGNAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTT
+
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
@r5959
CTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCNGTCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCGCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCCTCGCGCCGGTGCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGNCGGCATACTCCGTGGATGACATCCCGGNAAG
+
-D@!%+<3'*'2H$*G(5@:.0&-)>#>317D@1G*'<>8$E/1E,-:2"C5G:F5!B-1G!.?D#>A+2=5"3118E3F4#;==2=GA$1(>0(?;9.D7<-=D4%-&B''=<6&A84)"!.<G?F;:2"&=H**!9='B.2%?FEH-G"-BDGC-B&G<(*5,5<<4D;A?+B"B&!&+/.&>:"24F;,D6H7%#2+0CD8/.;,=F'A*"*BGGF3#&FG3G-,AFA0%'&10&2/-&36(@E*>!97:G:!>2G7*9#4H$:AE1D4'-:1-<0;0-,.6:%$?-!*G/@-@1!+2"H::(8::-B2,*31H0%"+$F1F
@r5960
TGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCNTAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACNNTATGAAAACCCACGTTGAGCCGACTATTCNTGATATTCCGTCGCTGCTGGCGCTGGCNCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTNCACTAGTGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTANGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACA
+
FD36H6!89,-<?>&9:0*#'E2C8H+04=#;:'2F%/#?>'A0:ABAH/4(:9&8F0:?H(,#'3CB"AC=,9+E=G2>CEH;;-<9"!,/C*3*%%%=:!/?@5:-"/1074481>F!9/<8>=$$(B:G<GH<:'@4GF$%-G?=*B/B.2170))1,(//;/>=E@03>29F-09F!>/*=H<>#/->6A'@D<F3(66:>7!5E47$/09((B*3A(1)D%'FE7.A(7=:A+1.>E)F)C#@,*74%E?ED:G/1ADA4*6!6>,$"9.E*%;2#F,:<H91;DG+*:A*C=F24A!@B95C:;>:83&,6,@;+H2B"+11E=""4"/)+#A+<:5);$FD.>%(/5>.!&&
@r5961
GTTCATCTCCTCACAGATAAAAAATCGCCCTCACACTGGA
+
E76?#!9(&4>2F;*8H?.H0B>C:,.</=";=2;<0:+H
@r5962
CAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCNGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATNCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATNCGGCACTGATGAACCAAAACAGCACAGCAGCACATAGCCCGGCTGTGCCGCTGACAACGGCACCTGANACAGCCCCGTCGCCTCCAGATTATCCAGATA
+
G@8/B)";%1%7@+7A3$@71$DD!1C/@!B?E<0'*/8H*/=F9+(9)9?<>B(,D+G-,&*:C46>)392!B9:0,:?,4>H2.:A55?8=62,)!>))C;)-*(G"-7"5B*+(A*880<#F&5@;%;D68%<-"=,?G-,-2:57><>/+!$B&6+.+:GG,4'2%;,;0%<&#%+;!73B@3!(C(6<@+*4#77.F;,=6?(E#4/4&(%5#99$&C2>!,1/=(>*:34!59(!%#4''A$3&4$:*22F+B:FCD1&0/*'6%E4;.+#85>F@*H7/>$8=7:@6*C6+!0?=445GBD@%-%((@:;7:=?E)=G2F)F21-54HGH@57B3'@C,89/*:H=0+?%H:2E&'2H%1HC48-1=$0>C
@r5963
ATTGCTACTTAGTCNGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTNGATTACTGTTATTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTNTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTANTTAGGANTAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTCTCACGAAGGTCAT
+
1.,8#C(721"B26;(#E'382-.6+&*4<C0=87>15BF/5<3/6#:0)-:16>D"$1"A<("G*(3@=#)#5(G&*+:*-9&&(!!:9/A"#4G>:@($1,&:<?;FG))G&%&3.!DE1<E/F.7%;E:;'0;#@;9-#)H$3GHH2@B?D>19-5$=#"+2567:BE;GDB01$?@"35H;79"0&'"-,,2*287'+*A0A,5&>@AC2(B:2=8G:>H%H4>(5")E($*.,GF:"F&,;+=4G?(=GFG8AF;7F:0'BC3"=&!-?;+?4H)D.""#>92$)9<767.D(//-6E.)6*F!@E-40.)H1=;E+H814%4>=),1%643=4FGG>;%7FC**#<'5)&9G*C$1;EA>:HC55"$977C?0*CG+A!D
@r5964
AAAAGTGGAAATCCGACAATTCTGGCAAACCATTTAACACACGTGCGAANTGTCCATGAATTTCTGAAAGAGTAACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCANACTACTAAATCCTGAATAGCTTTAAGAAGGTTATCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGGCCTACAAAACCAATTTTNACANTTCCGATATCGCATTTTGCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCNGCTC
+
.B89.#F-H2E2#5B!2893'A*E780;9-BEA"37C$4<7!*9*1A?!2,$'H!8CF?*;B6<"1F"(275<B)*!7B16.;#3$3#1F1/1<BH!,18:.,0$2>F6A'$(C5C=9$41>G1B(,.7:-AG$1+:+@C30=?52)&.4F!F8>,1=/;??HG7=:4A*.8CD:D!3/C6'(>G!0B&+'<B&'+4+=A8'=2;%6B7F=4+3:A9/@>C,,$+<.;5@01H)4?56==/;=?94/4<1$>B.D17.B*E>$;H&:<8<4B<H::'%8:1.#5;@HA'BC$8-=C#5&A3G35D&&:B:4!97,C34"4ABE&=FFD$"G."3:54H047"$&B#E642:H-19F8F>;C1<,<5<!55@%4.5B#;(%!38%<?;<,*.9&5$D'A"$?>)!$
@r5965
TAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCCATTTGCAAATACCNGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACNGGATCCCATGTCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAANCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTNATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGA
+
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
@r5966
TANGANNNNCATCTNNTAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATCAAACATCCCTCAAATGGGGGGANTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGCATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGNGGGACAGCAGAAGACCNGACCGCCGCAGAGTGGNTGTTTGACATGGTGAAGGCCATCGCACCATCANCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCNGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCNCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCATCAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTG
+
")#!'"#$"*%()!#'#$+""+'"+('#""++'!+#'*%$(*)"**&!#!(#!**#+(&(''"")+%)$"''%&++)&#$!$")!(!#'#)()'#+&#&%&!&)#&)*!"'%($%)*'#(+(*""!'!$*!&#"#+$*!)'(#%%*"%+&""$"&'*!%(+*+"#'+$$)%'%&&)%*%'&&'$%*(#%)'$$$($!#''&*%$!!'+%$#*$'"&#+"')'#'!($!+&**'(#*$#%)#!"&$%')*+#($+#)#'#$"!$')))#+&+!%*#)%'%(&'#%*"*)#$"&+$!!*+&+"$("'+&)"&!#$!*&+(%%''"+&"+#)'*)*"!!%*#&'$%%)*%*&#)"%')"%)(*#+$)%!''&'"+))**('$%%*(+*$+##$%'*$!*"$"&$"%()")!#$#**%)&#)#*!%'(''!$#%)&$*+)"*'%("$())$+''*"#'$!$*&+&(!+""()!#&'+$*)"!+$+(%**$*+)+!'%&#'(!$#+!#"""!+'&'!')'%#$!&&*$)&(!%*%'$##'&)%*)+*(%+'*!(&+&"%+
@r5967
GAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTNCTGCTCATTTGCCGTCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAANTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACNTGCCGGACTTNTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTNTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAAGTTTCTTTGCTCGGCATAAACATCCCTTACACTGGTGTGT
+
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
@r5968
CTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCNGTCTTCACGGACTTCGTTGCTTTCCAGTTAGCAATACGCTTACTCCCATCCGAGATAACACC
+
,G(.,248*C9!$5A=7"98<&+=4HF3C*0))4;%38A(E>:@:@6%!E/H27&-3.5>%C%G-!AC:?*HCG.4?>.'CF0=!4(%'FE(#4!/H*&39'78G#=;1=E7:6!:G<)3G$32FE1F(B5#/6!!#2)0/-EB)E72<+5F&H2<24.?..%#/GEA=HH!$A#*'H(.13&9GF6>C)-6@(D??>F>%A0',)&,(=/%,9,(.?8B7,H>?/:?&=31!:7$4:":C!)=3*7.2.EC6H-%>H-%1$.3B3!,3-834-6*+/;DH293!66+
@r5969
AACGNACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCAT
+
=EE(='%A=>=E8F7C*EF-BH15G7$H(;/),+-:)'."0B"G$E/<)4B6%9+3E$>C+/?A'#0#G1HF"?$-;0#.9'@##C*((
@r5970
TTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCANAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCAGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATTAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCNTTTGATGACGATGTTGAGTTTCAGGAGCNCNTGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGTTGGNAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTNATCACCACTCTTCNCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTT
+
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
@r5971
TNCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTTGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATC
+
(!*+"#*)&")')$&*+*!!%(!'))+)"%%#')#)$!))'')%(#"&)+&()'%"$&#$'%""!))$"'"!$*)(!%##!(")(*!'$*$%$"$((#"$)'$!!$)!%$$$$($))&#%!&%%+"!$*")+$'!%+
@r5972
CGGCCAGAATNTCTATCTGGATAATCTGGANGCGACGGGGCTGTATCAGGTGCCGTTGNCNGTGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCNGCCTTNACNGNCATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCATCAGAAACTGAGCGNCGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCCGCACGTCCGGGTTAACNGCGCAGTTACAGGNGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGNCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCACTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCNCCGTATACAGACAACGGATAACGGTAANCNGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAATCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGC
+
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
@r5973
CAAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCCTTTGGTCATACGCCAGCAGTGAAACCNCTCAAGTTTGCCAACCAAATGTATATCGATACCGTCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGC
+
&+!+(#)*"+%$#)((%)$)&*'(%*+)!+*!))#%""+%(!!#(&'"&#!(')('(&&!"(($%++"#&*&!($&%(#(!)%+#"$**''$#&$'+#)%#'""$!'#$+)""&%(#)!***)+(*)))#&%&%"(++*%$!"$#(!#!&%%%"!##%'")#+($!&*''$&!$)##&*'&(+!%($")&%'#"%')(*#(%#&+!$&!#*$&%%'$#(%!$$+$%%##"%#"+!%)!&(!$#$++))*#&#((%!)!'%&!$"%#''%+%$(+'*$!%!(#&('!)"&+%))((+)'"&!#&%))'(+*)&&+!+")'($$)+)
@r5974
CCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGC
+
)%CE6&+(#;1'@0-/&2!<#.4BG3*F%1!??A?#!A"4B(D)&7H9<>?%@61EC#+G.,%H9-$<1:%7<$F5G*/./9HHG'BE2FF9+3-
@r5975
GAGCGAAAACGCACGTTTNCCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGNTCAGGCCACCTGGGNTACCAGTTCGT
+
03@E?D;05="C?'FB%@)=;FGA&<+7-*<5H-(:"H%B,5(#-3,/-:CH=/*%%!E>3E6%(00?F)81')E)>+$748&8(@;6"E(0#+&>;:>%
@r5976
GCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCAT
+
F0%>(#%)#7@6*("/:@G?,GAA==2*#6;H;=A"H+(%)B200535B@>'>5"#C7:4;1'$F?")A-+&1HB/"8:=DA9<F"!-:$*,EE-BFF<E&/?/@D;9CH#;#!935/30);9/!
@r5977
GGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACACCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCNGAATAACNTCATGTCAGAGCAGAAAAAGACCTGGGCGNCTGAAGACCAGCTTCGCGGGAACTGGATGGC
+
-<90."/EF6C%0%H;;,0$<2-,0.5D:H%B$G+AH,(3>2&6B*79#B,.!8;@:)5--9/480D$6/!-)%E+E6720#)94?%%C2%G%#.,!DHFHHF%1F"=&9-/!A?8?)1>--4+(/H/(,?+F#</'5HGEDB804A/:<H2@</=.&>7<B-!?0B1%+(."@15?=<GA),@@GF14FD;C&1=>2#99*.):+>,4&#@!)/2D22<$+'6G@)B?(3<H(5-:-H<-9)&#G!:</2?G;$B-0@9.)*;H25(<$:/.6.2*4&4GF=6'
@r5978
TCCGGGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCNCTGCCGCGGCAGACGCAAAAACAGCGGNGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCNAAAAATTCGGCAAAACGTGCAGAAGNTATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCNACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGA
+
&7)!!6$0=(3(F*5?E080";5*$'?D@E46-<G;19=DB:4!90BH'(97!'<E83".5E56"*.E>@.?35?(1@1'>)&H&<00,!:!-99+3(%6F8:;F2@D;H2')'GC/D97(A<GD<?;(&GAC,:)/3,&B,<)%B!-,'4%0@3*'E<*8"%<&*A?")+ED6?84@!):*H@@=&;%@%=/E$2CA(@$5G?09?826?GC7E).@4,6E8'/<G-?-D!@,C*2"%D@%)A/@8*"=F+DF?A#;C*,-5("@;"*'>G;,D,#*=183C"$).*B3G9C'H-@"*F886"9E&/*0@'G3&,3F2(*D:+2?2G*B9*E",$%D?4H*E),2B$6(?DD2-2H6-A)@D*1;40E;;6AF!1B@-;G(D
@r5979
ACNTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACNTGGTACGTTTACGGTGGGCTA
+
')*+'+!($+!+))*"*"&*"%)&#"&*)"'(*%+!!$+#($)'")&!'!'#'*"#!"&#!$%!'*&+%(#$+!%+!"("!!#!+!))'$+$&"+'$!#(")!'!&(&)"&""!((&%&)*+!)%&%$*+"+)
@r5980
CAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAAT
+
/0"6>*"'81'F4*?@E=;",%8D?6)%<*><>34,E"7888A8961.1E2%0<A4H%,1E%!2>F/4C,CF#C<8E2!.0#5(4#@1-1B0$$C/76"HE)-!&?93G)D@%;H%27$>#$D1
@r5981
TGATGATATCCCGATTCCGGAAATCAANATGNCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAANACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCNTTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCNTTCGTACTCAATAGTTCCTGGCTGGAGATGTGCCTCGCTGGCCTGCCGCAGTTCTTCAATCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAANCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTGCCTGTTCCTGCCAGTTATGAATGGTANGGATACTCGCACCGAAAATGTNAGCCAGCTGCTTTTTGT
+
??A2);,,@5>,#F/7"D!0%(,!79@;@D7)1'B(#"G5&.&#?;E!6!!?+5@.H(0E2B=)4!.5HBDD+*>!@0+57"H)52<:*"$4!H@%H3/831>?H'@D!E+%$23:0=EC5!&,/!4"D(>4#DA+6'369&G%D:27"/BHE=502B/F<&#')/?A*6!F:0'27H4F>DDA%"'<,.%"%:@@0&FC(C(*3)C7=3HC'"H<""D")F'F:HG,A4!1*&70B.!00"4-5'2A/,$H97C>'1%%F)/8EC$F8,#.9;-<2?B7G)$'F27H;7F%&C:093+.$#G99G)7C!0/"#<(8.43<)C=5HH,C/G,31!7<71'3(061DF&98=#)>:-7==E=49A*+D$G*/D%%D91$+>43:0"8??$0/>)2!+"@@4B6,B$;8BG!BEB44'76?)'<,C''?F<5:##)*'#$H"&%'%H#<H1(6"#B@<C*G
@r5982
GTTAAAATATTACTTCAAATCTTTCTGTATGAAGATNTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTNAGTGAAAACATTCCTAATATTTGACATAAATCATCAGCAAAACACAAGGCGGTCAGACCAGATTGGAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACCGTNAATTGTTTTATTCTGAACTAAAACNTCAC
+
0H+.+364?3<:83E:,'1$CA=7C-H(&E0#)29CD'$0<A;<C(+F/H=643C.7H9:--0:5!1E%#12$5*9)7>4##;;0*?0),.+AD2@8#>9'D!CC%3"F$EG/7;57"A*GEE@D2:A948*=.!1>,&05C<%<*7"=9+:@<>*A)1$G$-<D(3'/*<.D$!!*<;-;5-F1%"%-+24B)E..1>6""D1/EHG!#.A9H#%A).%C=+/>/1'>AD4.;#09C!.ED6E8%2?$#0<.<"D/A/+)#/;*3&=FD0H53$(0)>#&*6%6&&%.+*:'"4E34'>#3F;G(:'GC.85/44E'A,.=F4(51>G6<+%AHC3;:>0
@r5983
GCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCNGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGNGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTNCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGNGACGAAAAAACGGACCGCGTTTGCCGGAACGNCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCNCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCGGAAATTTAAGTTTGATCCGCTGTNTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCNCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTNTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGCCCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGNTTCTGCCGTGCTTAAGGGC
+
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
@r5984
GTGNANTGCNGCNTNNTNAANCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCC
+
*("$!!*"#$!'!$!!'!)%*+""%#)&)*)%)!'!)"$$%*++)**#$!+&##'##&!'!!+!*&&&+(()"*%)%#'*##+"'*&+!(*$+'$
@r5985
CTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAG
+
+%%+"!*$"''"#**)$"!%$+*%()&$""""*"&+%(+#$!$*"
@r5986
NGCCACCGGCCGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATNTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGC
+
&'?G!=H,:'9/)CBD2*A51B(G#D?&@/G>-('A!2:+0=BG1C?.,2?-C>H7<35#<'91*+.&!7E7!%F<6;*&0:E?+<C6AH1<(C5%H=%5&75H@=F!(2#H/.&**/EF@<?/3G=>01F84FEE;@G?%
@r5987
CAAAGGTTCATTACTGAACACTCGTCCGAGAATAACNAGTGGATCCTTTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACNCGAGAACCACCGANCCTGATGTGGTTAAAAGACAGGCACANTCTTTACTACNGCAATCCANTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAGATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGANTGCATGGTTAAGCNTGAAGAAATGTTTCCTGTNATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTACTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTTCATTCCAACGAGTGAATACACGGAGCAATGTCG
+
$#%+&"+(!'&")'!&%$!*')**+))$%'!#&*#&*!!""$'&!+)!"+((#)'&)*##!*##(!$+*#('*"&'**(&')('''#%$('*+'#('+!!*"+'*('*!'*''*&(&&*##+$#&+&*%)%#!!$#&'%%$%)(%#$%#*"!$*)*"&$+%#+!'!(&&&%*%(&'%(*!+$%!$'!&*'(+&*)+"!+(+$&+(&*+%+(&#"%%*+*)!%("(&)("!'"$&$*'&'#!&)!()"(&*$'*$#&)&+!*'*)$&"&*(!"!)&+*+&+$"+&+!$*%'#(''"$(*''$'%"&+!$*$''""$!%&))##%'%+*#$)#'*)%"$"#$)"+$("!)''(#%%))*"*+)'*)'*%*'+##!*'")*(%(()%"&'#())%"))*#*&%%)+%"%("(!+&)'')'*($)&++#!*++"+&''$+"#!()))((+%+&)++(+"$%&#&$")(**'*#+&'+&%#((+&&)$++')%"+)"#!##)&))%###+(&&*$)!!+*##("*((&"+'(&"'+%%&+#$!#("*
@r5988
GATAGCCGCAAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCGGACCANAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTANTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGANATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGNCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCNGATATCAGTGGCAGTGTGANTGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGCTGGCCGTCAGGTACCCGTACTGT
+
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
@r5989
NCTGCAACAGGCTGCCAGCGATNCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCNATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTAAAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTT
+
"*@15#84C38(5'?4&>++&$FH209A4B1*1DDH<'42>,9"D?*$5)'E%063B>423%4C"3F%,F@1+.G@()(*,,D>B91/#/3/"B9.'-C5/HH+9="GC<B$-%=<%A,'+(7A#D.7:<!+*76G:B5%D+2,$?6+@-1<6</:.?*G&!9%3E''0"FE5:(H'973/=7*,+HHB4*&(3E-;D3+!=?86,8!((1E=*$0&)9%D$-G$-0:E*>D,)B!F6,!1#*D<*#5C=G48.,><4<("4*<4)9*>"%G/*'A?-#HC:5&#'6&'CD'*0*#$EG;.*7226;=105-5058$/#"5B'2!CC>9<$9!-8*A44CA6/9,-B35=9#+=D+#6;.,3=8FFDE5)-;':,);/9$#::(8)&8<FD'
@r5990
TGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTNTTCGGTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCGCATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATGTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTNGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTNCTCAAANTCTGACAGTTCAGCAAGANATCTGATTCCAGGCTTTGGCTTTAGCCACTTCNGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGT
+
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
@r5991
TCTGGCCAAAGTCCATCCGTGGCTCCNCGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAANACCGGGANATGGACCCGTGATGGCATT
+
;A:G/*:58G2.H%84@.#6*!@4"*8":BEF%/FC#6+7&B;/$,'9H&3D(/.6:$3D$?EB69-,>)E(=8C7G:+584A8%20A?&+HF6>,H4;/314(<!=:*3)H?C:C.)?*(68GA7,F#'F<;5G/H@.%GB:H#F&:+A6'<6<EC4"<C)B71&+)B@'#BC<*"39DCC7;<AG5.$3<G;:2C>8)&B6!!G.327+,95*7+7-G.?7@(04#./:5/@3<$EA*&6>C'B<'3DA;>9-E8=B;&@!F-DEB@F.*@&BE-G&6H&-2(,F/+,&?1>8<%9-'B:#0.
@r5992
GCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGA
+
8%=%8:!".A1BBGAA9>)DE'"H14)GB047AG7(H?4B&98@DCG5@2158B,,AF?A;B*&<8A8-=CH4&(#
@r5993
AGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAG
+
2G-:D%F0?3HFA@?&3%"?#6$>'-+G?B/:>F?E+F+8*G5,A3H@&8/?<:-A.&!6H<=#%>
@r5994
TGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGNCAATAAATGCGATACGATTGNCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCA
+
:BC)&.8/0;':1"955/(-FF();8((1<;786:+.@%.AA*6(?/A8#57$#=5"4),@0&"/3D:@A<B-8)$?&+;42$2#<#68C@G.1AA,+807.D82??-#-.?.1&H,='15:1
@r5995
CGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCATTT
+
82AHF91)=/;B.)<'9:%<#(7>#;*0$#@A.#42(!7>>F,+H4
@r5996
GGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAG
+
HH1>#<!:/4@$-9)92!*58>&E.%FF1()"9&/".7GHEH0!.(@&).0
@r5997
TATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTC
+
=.),=9@"0G:EB+:2:6B$HD:,-)?*2<)5A!&&3-%9?8!@E
@r5998
TTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGT
+
03ADC=()$5$'=;7C"=*3,:+%!3+B&50@3+08)$A9G5-A;2<(7C+*@B9#G'5%8B'A,D)-H=(;B">DBA>(**C+)'G',
@r5999
NGACACGGTTGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTNCGATAACCTGTTCGATGCTCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGACGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGANGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCNTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGCGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTAGCCGTATCAGC
+
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
@r6000
NAAATAGGNCNNGCNNTCNGGTANTANNCTNNGNGNNGCNGGCTGGTANCATCTNNTNNANANNTTNGCTTNCTNCNTNTACGAANTNCTNNNTGNAGCGNAAGANGNGCNNNATNANCNNTANNTTTCNTNCNNNNCNCNNCNGAGNNNN
+
$""#!!!#!"!""""#!#!"#$$!"$!$#!!!$!!!#!$""$$$!"#!!###$#""$!##!!"!##"#$$$#!$!#$""""#!!###!$""$""$$$##!$""$!$$!$$!$$"#"$$""##$#!$!$!"#"#"!!#$#$#$$!#$!!!#"