1Noteworthy changes in release 1.4.1  (8th May 2017)
2~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
3
4This is primarily a security bug fix update.
5
6* Fixed SECURITY issue with buffer overruns with malicious data. (#514).
7
8* S3 support for non Amazon AWS endpoints. (#506)
9
10* Support for variant breakpoints in bcftools. (#516)
11
12* Improved handling of BCF NaNs. (#485)
13
14* Compilation / portability improvements. (#255, #423, #498, #488)
15
16* Miscellaneous bug fixes (#482, #521, #522, #523, #524).
17
18* Sanitise headers (#509)
19
20
21Release 1.4 (13 March 2017)
22
23* Incompatible changes: several functions and data types have been changed
24  in this release, and the shared library soversion has been bumped to 2.
25
26  - bam_pileup1_t has an additional field (which holds user data)
27  - bam1_core_t has been modified to allow for >64K CIGAR operations
28    and (along with bam1_t) so that CIGAR entries are aligned in memory
29  - hopen() has vararg arguments for setting URL scheme-dependent options
30  - the various tbx_conf_* presets are now const
31  - auxiliary fields in bam1_t are now always stored in little-endian byte
32    order (previously this depended on if you read a bam, sam or cram file)
33  - index metadata (accessible via hts_idx_get_meta()) is now always
34    stored in little-endian byte order (previously this depended on if
35    the index was in tbi or csi format)
36  - bam_aux2i() now returns an int64_t value
37  - fai_load() will no longer save local copies of remote fasta indexes
38  - hts_idx_get_meta() now takes a uint32_t * for l_meta (was int32_t *)
39
40* HTSlib now links against libbz2 and liblzma by default.  To remove these
41  dependencies, run configure with options --disable-bz2 and --disable-lzma,
42  but note that this may make some CRAM files produced elsewhere unreadable.
43
44* Added a thread pool interface and replaced the bgzf multi-threading
45  code to use this pool.  BAM and CRAM decoding is now multi-threaded
46  too, using the pool to automatically balance the number of threads
47  between decode, encode and any data processing jobs.
48
49* New errmod_cal(), probaln_glocal(), sam_cap_mapq(), and sam_prob_realn()
50  functions, previously internal to SAMtools, have been added to HTSlib.
51
52* Files can now be accessed via Google Cloud Storage using gs: URLs, when
53  HTSlib is configured to use libcurl for network file access rather than
54  the included basic knetfile networking.
55
56* S3 file access now also supports the "host_base" setting in the
57  $HOME/.s3cfg configuration file.
58
59* Data URLs ("data:,text") now follow the standard RFC 2397 format and may
60  be base64-encoded (when written as "data:;base64,text") or may include
61  percent-encoded characters.  HTSlib's previous over-simplified "data:text"
62  format is no longer supported -- you will need to add an initial comma.
63
64* When plugins are enabled, S3 support is now provided by a separate
65  hfile_s3 plugin rather than by hfile_libcurl itself as previously.
66  When --enable-libcurl is used, by default both GCS and S3 support
67  and plugins will also be built; they can be individually disabled
68  via --disable-gcs and --disable-s3.
69
70* The iRODS file access plugin has been moved to a separate repository.
71  Configure no longer has a --with-irods option; instead build the plugin
72  found at <https://github.com/samtools/htslib-plugins>.
73
74* APIs to portably read and write (possibly unaligned) data in little-endian
75  byte order have been added.
76
77* New functions bam_auxB_len(), bam_auxB2i() and bam_auxB2f() have been
78  added to make accessing array-type auxiliary data easier.  bam_aux2i()
79  can now return the full range of values that can be stored in an integer
80  tag (including unsigned 32 bit tags).  bam_aux2f() will return the value
81  of integer tags (as a double) as well as floating-point ones.  All of
82  the bam_aux2 and bam_auxB2 functions will set errno if the requested
83  conversion is not valid.
84
85* New functions fai_load3() and fai_build3() allow fasta indexes to be
86  stored in a different location to the indexed fasta file.
87
88* New functions bgzf_index_dump_hfile() and bgzf_index_load_hfile()
89  allow bgzf index files (.gzi) to be written to / read from an existing
90  hFILE handle.
91
92* hts_idx_push() will report when trying to add a range to an index that
93  is beyond the limits that the given index can handle.  This means trying
94  to index chromosomes longer than 2^29 bases with a .bai or .tbi index
95  will report an error instead of apparantly working but creating an invalid
96  index entry.
97
98* VCF formatting is now approximately 4x faster.  (Whether this is
99  noticable depends on what was creating the VCF.)
100
101* CRAM lossy_names mode now works with TLEN of 0 or TLEN within +/- 1
102  of the computed value.  Note in these situations TLEN will be
103  generated / fixed during CRAM decode.
104
105* CRAM now supports bzip2 and lzma codecs.  Within htslib these are
106  disabled by default, but can be enabled by specifying "use_bzip2" or
107  "use_lzma" in an hts_opt_add() call or via the mode string of the
108  hts_open_format() function.
109
110Noteworthy changes in release 1.3.2  (13 September 2016)
111
112* Corrected bin calculation when converting directly from CRAM to BAM.
113  Previously a small fraction of converted reads would fail Picard's
114  validation with "bin field of BAM record does not equal value computed"
115  (SAMtools issue #574).
116
117* Plugins can now signal to HTSlib which of RTLD_LOCAL and RTLD_GLOBAL
118  they wish to be opened with -- previously they were always RTLD_LOCAL.
119
120
121Noteworthy changes in release 1.3.1  (22 April 2016)
122
123* Improved error checking and reporting, especially of I/O errors when
124  writing output files (#17, #315, PR #271, PR #317).
125
126* Build fixes for 32-bit systems; be sure to run configure to enable
127  large file support and access to 2GiB+ files.
128
129* Numerous VCF parsing fixes (#321, #322, #323, #324, #325; PR #370).
130  Particular thanks to Kostya Kortchinsky of the Google Security Team
131  for testing and numerous input parsing bug reports.
132
133* HTSlib now prints an informational message when initially creating a
134  CRAM reference cache in the default location under your $HOME directory.
135  (No message is printed if you are using $REF_CACHE to specify a location.)
136
137* Avoided rare race condition when caching downloaded CRAM reference sequence
138  files, by using distinctive names for temporary files (in addition to O_EXCL,
139  which has always been used).  Occasional corruption would previously occur
140  when multiple tools were simultaneously caching the same reference sequences
141  on an NFS filesystem that did not support O_EXCL (PR #320).
142
143* Prevented race condition in file access plugin loading (PR #341).
144
145* Fixed mpileup memory leak, so no more "[bam_plp_destroy] memory leak [...]
146  Continue anyway" warning messages (#299).
147
148* Various minor CRAM fixes.
149
150* Fixed documentation problems #348 and #358.
151
152
153Noteworthy changes in release 1.3  (15 December 2015)
154
155* Files can now be accessed via HTTPS and Amazon S3 in addition to HTTP
156  and FTP, when HTSlib is configured to use libcurl for network file access
157  rather than the included basic knetfile networking.
158
159* HTSlib can be built to use remote access hFILE backends (such as iRODS
160  and libcurl) via a plugin mechanism.  This allows other backends to be
161  easily added and facilitates building tools that use HTSlib, as they
162  don't need to be linked with the backends' various required libraries.
163
164* When writing CRAM output, sam_open() etc now default to writing CRAM v3.0
165  rather than v2.1.
166
167* fai_build() and samtools faidx now accept initial whitespace in ">"
168  headers (e.g., "> chr1 description" is taken to refer to "chr1").
169
170* tabix --only-header works again (was broken in 1.2.x; #249).
171
172* HTSlib's configure script and Makefile now fully support the standard
173  convention of allowing CC/CPPFLAGS/CFLAGS/LDFLAGS/LIBS to be overridden
174  as needed.  Previously the Makefile listened to $(LDLIBS) instead; if you
175  were overriding that, you should now override LIBS rather than LDLIBS.
176
177* Fixed bugs #168, #172, #176, #197, #206, #225, #245, #265, #295, and #296.
178
179
180Noteworthy changes in release 1.2.1  (3 February 2015)
181
182* Reinstated hts_file_type() and FT_* macros, which were available until 1.1
183  but briefly removed in 1.2.  This function is deprecated and will be removed
184  in a future release -- you should use hts_detect_format() etc instead
185
186
187Noteworthy changes in release 1.2  (2 February 2015)
188
189* HTSlib now has a configure script which checks your build environment
190  and allows for selection of optional extras.  See INSTALL for details
191
192* By default, reference sequences are fetched from the EBI CRAM Reference
193  Registry and cached in your $HOME cache directory.  This behaviour can
194  be controlled by setting REF_PATH and REF_CACHE enviroment variables
195  (see the samtools(1) man page for details)
196
197* Numerous CRAM improvements:
198  - Support for CRAM v3.0, an upcoming revision to CRAM supporting
199    better compression and per-container checksums
200  - EOF checking for v2.1 and v3.0 (similar to checking BAM EOF blocks)
201  - Non-standard values for PNEXT and TLEN fields are now preserved
202  - hts_set_fai_filename() now provides a reference file when encoding
203  - Generated read names are now numbered from 1, rather than being
204    labelled 'slice:record-in-slice'
205  - Multi-threading and speed improvements
206
207* New htsfile command for identifying file formats, and corresponding
208  file format detection APIs
209
210* New tabix --regions FILE, --targets FILE options for filtering via BED files
211
212* Optional iRODS file access, disabled by default.  Configure with --with-irods
213  to enable accessing iRODS data objects directly via 'irods:DATAOBJ'
214
215* All occurences of 2^29 in the source have been eliminated, so indexing
216  and querying against reference sequences larger than 512Mbp works (when
217  using CSI indices)
218
219* Support for plain GZIP compression in various places
220
221* VCF header editing speed improvements
222
223* Added seq_nt16_int[] (equivalent to the samtools API's bam_nt16_nt4_table)
224
225* Reinstated faidx_fetch_nseq(), which was accidentally removed from 1.1.
226  Now faidx_fetch_nseq() and faidx_nseq() are equivalent; eventually
227  faidx_fetch_nseq() will be deprecated and removed [#156]
228
229* Fixed bugs #141, #152, #155, #158, #159, and various memory leaks
230